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Results for "

nootropic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenylate Cyclase (4) Amyloid-β (2) Apoptosis (3) Calcium Channel (4) Dopamine Transporter (3) Drug Derivative (5) Drug Intermediate (1) Free Fatty Acid Receptor (2) GABA Receptor (7) iGluR (6) Isotope-Labeled Compounds (2) mAChR (1) Melatonin Receptor (2) nAChR (2) Sigma Receptor (2) TNF Receptor (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (7) Inflammation/Immunology (5) Metabolic Disease (7) Neurological Disease (37)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1124A

Fipexide hydrochloride 1 Publications Verification	Adenylate Cyclase Dopamine Transporter	Neurological Disease
Fipexide hydrochloride, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide hydrochloride reduces striatal adenylate cyclase activity. Fipexide hydrochloride has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide hydrochloride is used for senile dementia research. Fipexide hydrochloride acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection .

HY-B1124

Fipexide 1 Publications Verification	Adenylate Cyclase Dopamine Transporter	Neurological Disease
Fipexide, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide reduces striatal adenylate cyclase activity. Fipexide has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide is used for senile dementia research. Fipexide acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection .

HY-10932

Aniracetam Ro 13-5057	nAChR iGluR	Neurological Disease
Aniracetam (Ro 13-5057) is an orally active neuroprotective agent, possessing nootropics effects. Aniracetam potentiates the ionotropic quisqualate (iQA) responses in the CA1 region of rat hippocampal slices. Aniracetam also potentiates the excitatory post synaptic potentials (EPSPs) in Schaffer collateral-commissural synapses. Aniracetam can prevents the CO₂-induced impairment of acquisition in hypercapnia model rats. Aniracetam can be used to research cerebral dysfunctional disorders .

HY-P1146

Semax	Amyloid-β	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Semax is a BBB-penetrable adrenocorticotropic hormone-like peptide and can form stable complexes with Cu ²⁺. Semax is a synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10). Semax has immunomodulatory, nootropic and neuroprotective activities. Semax can be used in the research of central nervous system diseases such as Alzheimer's disease and cerebral ischemia .

HY-P1146A

Semax acetate	Amyloid-β	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Semax acetate is a BBB-penetrable adrenocorticotropic hormone-like peptide and can form stable complexes with Cu ²⁺. Semax acetate is a synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10). Semax acetate has immunomodulatory, nootropic and neuroprotective activities. Semax acetate can be used in the research of central nervous system diseases such as Alzheimer's disease and cerebral ischemia .

HY-B1558

Bifemelane MCI-2016 free base	Calcium Channel	Neurological Disease
Bifemelane is a nootropic compound. Bifemelan causes the first peak by stimulating release from intracellular Ca ²⁺ stores and the second by capacitive entry through store–operated Ca ²⁺ channels. Bifemelane will be provided as a pharmacological tool for basic studies on astrocytes .

HY-151951

Antidepressant agent 4	GABA Receptor Melatonin Receptor Sigma Receptor	Neurological Disease
Antidepressant agent 4 is an orally active antidepressant agent. Antidepressant agent 4 exhibits antidepressant, anxiolytic, performance enhancing and nootropic activities .

HY-151950

Antidepressant agent 3	GABA Receptor Melatonin Receptor Sigma Receptor	Neurological Disease
Antidepressant agent 3 is an orally active antidepressant agent. Antidepressant agent 3 exhibits antidepressant, anxiolytic, performance enhancing and nootropic activities .

HY-120547

UCB-11056	Adenylate Cyclase	Neurological Disease Metabolic Disease
UCB-11056 is a modulator of cyclic AMP generation. UCB-11056 can rapidly increase cyclic AMP levels in the rat brain in vivo and potentiate stimulated cyclic AMP formation in vitro. UCB-11056 does not stimulate cAMP formation on its own. UCB-11056 is a potential nootropic drug .

HY-B1124R

Fipexide (Standard)	Adenylate Cyclase Dopamine Transporter	Neurological Disease
Fipexide (Standard) is the analytical standard of Fipexide. This product is intended for research and analytical applications. Fipexide, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide reduces striatal adenylate cyclase activity. Fipexide has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide is used for senile dementia research. Fipexide acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection .

HY-10932R

Aniracetam (Standard)	nAChR iGluR	Neurological Disease
Aniracetam (Standard) is the analytical standard of Aniracetam. This product is intended for research and analytical applications. Aniracetam (Ro 13-5057) is an orally active neuroprotective agent, possessing nootropics effects. Aniracetam potentiates the ionotropic quisqualate (iQA) responses in the CA1 region of rat hippocampal slices. Aniracetam also potentiates the excitatory post synaptic potentials (EPSPs) in Schaffer collateral-commissural synapses. Aniracetam can prevents the CO₂-induced impairment of acquisition in hypercapnia model rats. Aniracetam can be used to research cerebral dysfunctional disorders .

HY-17554

(R)-Oxiracetam (R)-(+)-Oxiracetam; (R)-ISF2522	Others	Neurological Disease
(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam.

HY-129048

Fladrafinil CRL-40,941	Drug Derivative	Neurological Disease
Fladrafinil (CRL-40,941) is a nootropic .

HY-14840

Phenylpiracetam	GABA Receptor	Neurological Disease
Phenylpiracetam(Phenotropyl; Phenotropil) is a phenylated derivative of the nootropic drug piracetam.

HY-170719

4-Chloro modafinil	Drug Derivative	Neurological Disease
4-Chloro modafinil is structurally similar to known nootropics.

HY-117984

RU 35929	Drug Derivative	Neurological Disease
RU 35929 is a nootropic agent. RU 35929 enhances learning and memory .

HY-17456

Omberacetam GVS-111; SGS-111	iGluR	Neurological Disease
Omberacetam (GVS-111) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic.

HY-114946

N-methyl-4,4-difluoro Modafinil	Drug Derivative	Neurological Disease
N-methyl-4,4-difluoro Modafinil is categorized as a nootropic .

HY-119602

Rolziracetam CI-911	Others	Neurological Disease
Rolziracetam is a nootropic agent of the racetam family and improves short-term memory in rats and monkeys .

HY-118583A

4-Fluoro phenibut hydrochloride β-(4-Fluorophenyl)-GABA hydrochloride; F-Phenibut hydrochloride	Drug Derivative	Neurological Disease
4-Fluoro phenibut (β-(4-Fluorophenyl)-GABA) hydrochloride is a Gabapentinoid and is structurally similar to known nootropics .

HY-B0106A

Etiracetam UCB 6474	Calcium Channel	Neurological Disease
Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) .

HY-17456R

Omberacetam (Standard)	iGluR	Neurological Disease
Omberacetam (Standard) is the analytical standard of Omberacetam. This product is intended for research and analytical applications. Omberacetam (GVS-111) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic.

HY-108403

Phenibut β-Phenyl-GABA; 4-Amino-3-phenylbutanoic acid	GABA Receptor	Neurological Disease
Phenibut (β-Phenyl-GABA) is a GABA-B agonist . Phenibut acts as a GABA-mimetic, primarily at GABAB receptors. Phenibut has anxiolytic and nootropic (cognition enhancing) effects .

HY-113970A

Nebracetam hydrochloride WEB 1881 FU hydrochloride	mAChR	Neurological Disease
Nebracetam hydrochloride, a nootropic M₁-muscarinic agonist, induces a rise of intracellular Ca ²⁺ concentration. Nebracetam hydrochloride exhibits an EC₅₀ of 1.59 mM for elevating [Ca ²⁺]_i .

HY-W041333

Phenibut hydrochloride β-Phenyl-GABA hydrochloride; 4-Amino-3-phenylbutanoic acid hydrochloride; 4-Amino-3-phenylbutyric acid hydrochloride	GABA Receptor	Neurological Disease
Phenibut (β-Phenyl-GABA) hydrochloride is an orally active GABA-B agonist . Phenibut hydrochloride acts as a GABA-mimetic, primarily at GABAB?receptors. Phenibut hydrochloride has anxiolytic and nootropic (cognition enhancing) effects .

HY-B0106AS

Etiracetam-d3 UCB 6474-d₃	Isotope-Labeled Compounds Calcium Channel	Neurological Disease
Etiracetam-d₃ is the deuterium labeled Etiracetam. Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) .

HY-B0106AR

Etiracetam (Standard)	Calcium Channel	Neurological Disease
Etiracetam (Standard) is the analytical standard of Etiracetam. This product is intended for research and analytical applications. Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) .

HY-107482

Picamilon Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid	GABA Receptor	Neurological Disease
Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats .

HY-107482A

Picamilon sodium Nicotinoyl-GABA sodium; Nicotinoyl-γ-aminobutyric acid sodium; Sodium 4-(nicotinamido)butanoate	GABA Receptor	Neurological Disease
Picamilon sodium is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon sodium improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats .

HY-W017851

4-Phenyl-2-pyrrolidinone	Drug Intermediate	Neurological Disease
4-Phenyl-2-pyrrolidinone is a precursor and synthetic intermediate. 4-Phenyl-2-pyrrolidinone can be used as a precursor in the synthesis of compounds with anticonvulsant and nootropic activities and is an intermediate in the synthesis of bromodomain-containing protein 4 (BRD4) bromodomain 1 inhibitors .

HY-131528

Tenilsetam CAS 997	TNF Receptor	Neurological Disease Metabolic Disease
Tenilsetam (CAS 997) is an antidementia compound. Tenilsetam is an advanced glycation end product (AGE) inhibitor. Tenilsetam inhibits early retinopathy in experimental diabetes rats .

HY-N0264

Ligustrazine Maximum Cited Publications 6 Publications Verification Chuanxiongzine; Tetramethylpyrazine	Apoptosis	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) , is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats .

HY-17550

Sunifiram DM-235	iGluR	Neurological Disease
Sunifiram (DM-235) is an ampakine-like compound and an agonist of AMPA receptor with oral activity. Sunifiram can increase the release of acetylcholine in the rat cerebral cortex and exhibits potent cognitive enhancement effects with better nootropic activity compared to piracetam (HY-B0585). Sunifiram is promising for research in neurodegenerative diseases such as mild cognitive impairment (MCI) and Alzheimer's disease (AD) .

HY-N0264R

Ligustrazine (Standard)	Apoptosis	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Ligustrazine (Standard) is the analytical standard of Ligustrazine. This product is intended for research and analytical applications. Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) , is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats .

HY-N0264S1

Ligustrazine-d12 Chuanxiongzine-d₁₂; Tetramethylpyrazine-d₁₂	Isotope-Labeled Compounds Apoptosis	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Ligustrazine-d₁₂ (Chuanxiongzine-d₁₂) is deuterium labeled Ligustrazine. Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) , is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats .

HY-17550R

Sunifiram (Standard)	iGluR	Neurological Disease
Sunifiram (Standard) is the analytical standard of Sunifiram. This product is intended for research and analytical applications. Sunifiram (DM-235) is an ampakine-like compound and an agonist of AMPA receptor with oral activity. Sunifiram can increase the release of acetylcholine in the rat cerebral cortex and exhibits potent cognitive enhancement effects with better nootropic activity compared to piracetam (HY-B0585). Sunifiram is promising for research in neurodegenerative diseases such as mild cognitive impairment (MCI) and Alzheimer's disease (AD) .

HY-B1021R

Vincamine (Standard)	Free Fatty Acid Receptor	Cardiovascular Disease Metabolic Disease
Vincamine (Standard) is the analytical standard of Vincamine. This product is intended for research and analytical applications. Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation . Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research .

HY-B1021

Vincamine 1 Publications Verification	Free Fatty Acid Receptor	Cardiovascular Disease Metabolic Disease
Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation . Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research .

Cat. No.	Product Name	Target	Research Area

HY-105042A

Selank diacetate Selanc diacetate; TP-7 diacetate	Peptides	Neurological Disease
Selank (Selanc) acetate is a synthetic peptide derived from tuftsin. Selank acetate has anxiolytic activity, and is a nootropic, neuropsychotropic, antidepressant, and antistress compound .

HY-P1146

Semax	Amyloid-β	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Semax is a BBB-penetrable adrenocorticotropic hormone-like peptide and can form stable complexes with Cu ²⁺. Semax is a synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10). Semax has immunomodulatory, nootropic and neuroprotective activities. Semax can be used in the research of central nervous system diseases such as Alzheimer's disease and cerebral ischemia .

HY-P1146A

Semax acetate	Amyloid-β	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Semax acetate is a BBB-penetrable adrenocorticotropic hormone-like peptide and can form stable complexes with Cu ²⁺. Semax acetate is a synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10). Semax acetate has immunomodulatory, nootropic and neuroprotective activities. Semax acetate can be used in the research of central nervous system diseases such as Alzheimer's disease and cerebral ischemia .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0264

Ligustrazine 5+ Cited Publications Chuanxiongzine; Tetramethylpyrazine	Cardiovascular Disease Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Metabolic Disease Dicerothamnus rhinocerotis Umbelliferae Plants Inflammation/Immunology Disease Research Fields	Apoptosis
Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) , is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats .

HY-B1021

Vincamine 1 Publications Verification	Apocynaceae Cardiovascular Disease Alkaloids Structural Classification Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids Catharanthus roseus (L.) G. Don	Free Fatty Acid Receptor
Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation . Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research .

HY-N0264R

Ligustrazine (Standard)	Structural Classification Natural Products Source classification Dicerothamnus rhinocerotis Umbelliferae Plants	Apoptosis
Ligustrazine (Standard) is the analytical standard of Ligustrazine. This product is intended for research and analytical applications. Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) , is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats .

HY-B1021R

Vincamine (Standard)	Apocynaceae Alkaloids Structural Classification Source classification Plants Indole Alkaloids Catharanthus roseus (L.) G. Don	Free Fatty Acid Receptor
Vincamine (Standard) is the analytical standard of Vincamine. This product is intended for research and analytical applications. Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation . Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research .

Cat. No.	Product Name	Chemical Structure

HY-B0106AS

Etiracetam-d3
Etiracetam-d₃ is the deuterium labeled Etiracetam. Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) .

HY-N0264S1

Ligustrazine-d12

Ligustrazine-d₁₂ (Chuanxiongzine-d₁₂) is deuterium labeled Ligustrazine. Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) , is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats .

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nootropic

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products