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microbial metabolism

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29

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3

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0172B

    Endogenous Metabolite Endocrinology
    Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate .
    Isolithocholic acid
  • HY-W015969

    Monoisopropanolamine

    Endogenous Metabolite Metabolic Disease
    1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .
    1-Aminopropan-2-ol
  • HY-W278566

    Drug Metabolite Cardiovascular Disease Metabolic Disease
    Saluamine is an important N-dealkylated metabolite of Furosemide (HY-B0135) that is produced by microbial transformation and bile metabolism .
    Saluamine
  • HY-41325

    7,12-Dioxolithocholic acid; 3-Hydroxy-7,12-diketocholanoic acid; 7,12-Diketo-LCA

    Endogenous Metabolite Others
    7,12-Diketolithocholic acid (7,12-Diketo-LCA) is a bile acid, which can be produced in the host-gut microbial co-metabolism of the bile acid pool .
    7,12-Diketolithocholic acid
  • HY-126574

    Endogenous Metabolite Others
    Pantothenoylcysteine is the biosynthetic precursor of CoA. Pantothenoylcysteine can be used to study microbial metabolism .
    Pantothenoylcysteine
  • HY-135024B

    Phenylacetyl Coenzyme A tetrasodium

    Others Metabolic Disease
    Phenylacetyl Coenzyme A (Phenylacetyl Coenzyme A) tetrasodium is an effector molecule of the TetR family transcriptional repressor PaaR. Phenylacetyl Coenzyme A tetrasodium changes the conformation of PaaR, causing it to dissociate from DNA and initiate transcription. Phenylacetyl Coenzyme A tetrasodium is promising for research of microbial metabolism .
    Phenylacetyl CoA tetrasodium
  • HY-B0172BR

    Reference Standards Endogenous Metabolite Endocrinology
    Isolithocholic acid (Standard) is the analytical standard of Isolithocholic acid. This product is intended for research and analytical applications. Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate[1][2].
    Isolithocholic acid (Standard)
  • HY-N10475

    Endogenous Metabolite Others
    4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone (compound 3) is a hydroxylated microbial metabolite of Yangonin .
    4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone
  • HY-W403633

    Bacterial Infection
    Hexahydrohippuric acid is a metabolite of Shikimate acid in both liver and kidney, under microbial metabolism effect. Hexahydrohippuric acid is made of cyclohexane carboxylic acid and glycinamide, and shows antibacterial activity .
    Hexahydrohippuric acid
  • HY-W102516

    Δ6-Progesterone

    Endogenous Metabolite Others
    6-Dehydroprogesterone (Δ6-Progesterone) is a steroid compound that can be found in Botryodiplodia theobromae. 6-Dehydroprogesterone is a metabolic product of Progesterone (HY-N0437) after a microbial dehydrogenation reaction. 6-Dehydroprogesterone can be used to study steroid metabolism pathways, microbial dehydrogenase activity, and the biotransformation of steroids .
    6-Dehydroprogesterone
  • HY-W015969R

    Monoisopropanolamine (Standard)

    Reference Standards Endogenous Metabolite Metabolic Disease
    1-Aminopropan-2-ol (Standard) is the analytical standard of 1-Aminopropan-2-ol. This product is intended for research and analytical applications. 1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .
    1-Aminopropan-2-ol (Standard)
  • HY-138933

    Endogenous Metabolite
    (±)-Geosmin is a natural organic compound with biological activity that causes earthy aroma. (±)-Geosmin plays an important role in microbial metabolism and is commonly used as a fragrance in food and air. (±)-Geosmin has also been studied for detecting soil and water pollution.
    (±)-Geosmin
  • HY-W752616

    Monoisopropanolamine-d6

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    1-Aminopropan-2-ol-d6 (Monoisopropanolamine-d6) is the deuterium labeled 1-Aminopropan-2-ol (HY-W015969). 1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .
    1-Aminopropan-2-ol-d6
  • HY-W278566R

    Reference Standards Drug Metabolite Cardiovascular Disease Metabolic Disease
    Saluamine (Standard) is the analytical standard of Saluamine (HY-W278566). This product is intended for research and analytical applications. Saluamine is an important N-dealkylated metabolite of Furosemide (HY-B0135) that is produced by microbial transformation and bile metabolism .
    Saluamine (Standard)
  • HY-N0321

    trans-Caftaric acid

    Others Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Caftaric acid (trans-Caftaric acid) is a polyphenolic antidiuretic, antioxidant and anti-apoptotic agent that can be hydrolyzed by intestinal microbial esterases. Caftaric acid exerts its antioxidant and potential anti-inflammatory effects mainly through intestinal microbial metabolism. Caftaric acid can reduce renal damage, restore electrolyte balance, renal function indicators and antioxidant enzyme activities in a rat albinism model, and further exert anti-oxidative stress and anti-inflammatory activities .
    Caftaric acid
  • HY-Y0520
    Itaconic acid
    2 Publications Verification

    Methylenesuccinic acid

    Endogenous Metabolite Ferroptosis Inflammation/Immunology Cancer
    Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .
    Itaconic acid
  • HY-B1145
    Chlorhexidine dihydrochloride
    Maximum Cited Publications
    12 Publications Verification

    Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine dihydrochloride
  • HY-W013699
    Chlorhexidine diacetate
    Maximum Cited Publications
    12 Publications Verification

    Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine diacetate is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine diacetate binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine diacetate has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine diacetate can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine diacetate
  • HY-B1248A

    Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine acetate hydrate is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine acetate hydrate binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine acetate hydrate has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine acetate hydrate can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine acetate hydrate
  • HY-B1248
    Chlorhexidine
    Maximum Cited Publications
    12 Publications Verification

    Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine
  • HY-B1145S

    Isotope-Labeled Compounds Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine-d8 (dihydrochloride) is the deuterium labeled Chlorhexidine dihydrochloride (HY-B1145). Chlorhexidine dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine-d8 dihydrochloride
  • HY-W017766

    PHMB

    Bacterial Infection
    Poly(hexamethylenebiguanide) hydrochloride (PHMB) is an antimicrobial and antiviral agent. Poly(hexamethylenebiguanide) hydrochloride is active against both Gram-positive and Gram-negative bacteria. Poly(hexamethylenebiguanide) hydrochloride works by adsorbing to the surface of cellulose, which can damage microbial cell membranes and interfere with metabolism. Poly(hexamethylenebiguanide) hydrochloride is widely used in medical, clothing and household textiles, and cosmetic fields .
    Poly(hexamethylenebiguanide) hydrochloride
  • HY-W738281

    Isotope-Labeled Compounds Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine-d8 is deuterium-labeled Chlorhexidine (HY-B1248) . Chlorhexidine is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine-d8
  • HY-B0608
    Chlorhexidine digluconate (20% in water)
    Maximum Cited Publications
    12 Publications Verification

    Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine digluconate (20% in water) is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine digluconate (20% in water) binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine digluconate (20% in water) has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine digluconate (20% in water) can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine digluconate (20% in water)
  • HY-B1248R

    Reference Standards Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine (Standard) is the analytical standard of Chlorhexidine (HY-B1248). This product is intended for research and analytical applications. Chlorhexidine is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine (Standard)
  • HY-B1145R

    Reference Standards Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine dihydrochloride (Standard) is the analytical standard of Chlorhexidine dihydrochloride (HY-B1145). This product is intended for research and analytical applications. Chlorhexidine dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine dihydrochloride (Standard)
  • HY-W013699R

    Reference Standards Antibiotic Bacterial Necroptosis Apoptosis Infection
    Chlorhexidine diacetate (Standard) is the analytical standard of Chlorhexidine diacetate (HY-W013699). This product is intended for research and analytical applications. Chlorhexidine diacetate is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine diacetate binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine diacetate has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine diacetate can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
    Chlorhexidine diacetate (Standard)
  • HY-Y0520R

    Methylenesuccinic acid (Standard)

    Reference Standards Endogenous Metabolite Ferroptosis Inflammation/Immunology
    Itaconic acid (Standard) is the analytical standard of Itaconic acid. This product is intended for research and analytical applications. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .
    Itaconic acid (Standard)
  • HY-N7921

    Bacterial Others
    Urolithin M6 is a polyhydroxy-rich metabolite with potential antioxidant activity. Urolithin M6 is produced by intestinal microbial metabolism and may act as an analog of tannic acid compounds. The production of Urolithin M6 in humans requires specific bacterial 3-dehydroxylase activity, which provides a new mechanism for its biotransformation. The metabolic profile of Urolithin M6 helps to stratify volunteers and further explore its potential role in health and disease .
    Urolithin M6

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