Search Result
Results for "
maleimides
" in MedChemExpress (MCE) Product Catalog:
137
Biochemical Assay Reagents
5
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-140740
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Liposome
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Cancer
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DSPE-PEG-Maleimide, MW 5000 has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-maleimide extends blood circulation time and higher stability for encapsulated agents .
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- HY-144004
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DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
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Liposome
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Others
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DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
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- HY-166648A
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Liposome
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Others
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DSPE-PEG-Maleimide (ammonium) (MW 2000) has DSPE phospholipids and maleimide to prepare nanostructured lipid carriers. DSPE-PEG-Maleimide (ammonium) (MW 2000) can be used in drug delivery research .
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- HY-144004A
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DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
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Liposome
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Others
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DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
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- HY-W011618
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Fluorescent Dye
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Others
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N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione .
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- HY-115756
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Others
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Others
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4-Maleimidosalicylic acid is a polar maleimide, and does not suppress IL-2 production in JURKAT T cells .
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- HY-W998680
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5-FITC-Maleimide
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Fluorescent Dye
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Others
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Fluorescein-maleimide is a fluorescein dye linker containing a maleimide group. The maleimides in Fluorescein-maleimide react with thiol-containing compounds or biomolecules to form thioester bonds between pH 6.5 and 7.5. Fluorescein-maleimide is specifically designed for fluorescent labeling of proteins, nucleic acids, or other molecules containing one or more thiol groups .
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- HY-137098
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Fluorescent Dye
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Others
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Sulfo-Cy3 maleimide potassium is a fluorescent dye with a maleimide functionality at the end a short alkyl linker. Sulfo-Cy3 maleimide potassium can be used for the labeling of antibodies and other labile proteins .
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- HY-D2182
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Fluorescent Dye
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Others
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Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
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- HY-D2180
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Fluorescent Dye
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Others
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Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
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- HY-140739
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Liposome
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Neurological Disease
Cancer
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DSPE-PEG2000-Maleimide is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
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- HY-D0069
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Fluorescent Dye
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Others
Cancer
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CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm) .
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- HY-140739A
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Liposome
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Neurological Disease
Cancer
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DSPE-PEG2000-Maleimide free acid is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide free acid utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide free acid covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide free acid can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
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- HY-W441004
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Liposome
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Others
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DSPE-Thiol is a phophalipid capped with thiol group. The thiol capped head can selectively react with maleimide. DSPE-Thiol can also be used for the preparation of phospholipid dimers .
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- HY-D1363
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Fluorescent Dye
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Others
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BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .
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- HY-151940
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Reactive Oxygen Species (ROS)
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Cancer
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Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species)-mediated effect of photodynamic therapy (PDT) in cancer cells .
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- HY-W879048
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ADC Linker
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Others
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DBCO-PEG24-Maleimide contains a maleimide and a DBCO group. DBCO-PEG24-Maleimide can be used for thiol-containing biomolecule conjugations. DBCO-PEG24-Maleimide can be used in click chemistry with azide-bearing biomolecules .
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- HY-159674
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N-Tetamine-polySarcosine45-Maleimide
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Biochemical Assay Reagents
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Others
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N-Tetamine-pSar45-Maleimide (N-Tetamine-polySarcosine45-Maleimide) is a pSar-lipid derivative. As a hydrophilic alternative to PEG, N-Tetamine-pSar45-Maleimide can be used in drug delivery research .
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- HY-D0098
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N-(5-Fluoresceinyl)maleimide
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Fluorescent Dye
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Others
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Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
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- HY-D2103
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Fluorescent Dye
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Others
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TAMRA-PEG3-Maleimide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Maleimide contains maleimide groups that react with thiol groups to form covalent bonds.
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- HY-D2104
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Fluorescent Dye
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Others
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TAMRA-PEG7-Maleimide is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
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- HY-W190932
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Fluorescent Dye
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Others
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TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
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- HY-W540192
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ADC Linker
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Cancer
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SCO-PEG2-Maleimide is an ADC Linker containing 3 PEG units. SCO-PEG2-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-156318
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ADC Linker
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Cancer
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SCO-PEG3-Maleimide is a cleavable ADC Linker containing 3 PEG units. SCO-PEG3-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-156321
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ADC Linker
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Cancer
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SCO-PEG7-Maleimide is a cleavable ADC Linker containing 3 PEG units. SCO-PEG7-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-156377
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Drug-Linker Conjugates for ADC
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Cancer
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Biotin-PEG7-Maleimide is a biotinylation reagent that reacts with thiol groups (SH). Biotin-PEG7-Maleimide can be used as Drug-Linker Conjugates for ADCs .
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- HY-D1592
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Fluorescent Dye
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Others
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BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .
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- HY-D1364
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Biochemical Assay Reagents
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Others
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Pyrene maleimide is a polyaromatic fluorescent hydrocarbon with a termininal maleimide group. The maleimide group will react with a thiol group to form a covalent bond.
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- HY-D2488
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Fluorescent Dye
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Others
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Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.
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- HY-157919
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N-6-(Biotinylamino)hexanoyl-N'-[2-(N-maleimido)ethyl]piperazine, hydrochloride
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Biochemical Assay Reagents
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Others
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Biotin-PEAC5-maleimide hydrochloride is a biochemical assay reagent, and can be used in biotin-PEAC5-maleimide (BPM)-labeling assay to assess modification of protein thiols by electrophiles .
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- HY-W739513
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- HY-156307
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ADC Linker
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Cancer
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Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-156312
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ADC Linker
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Cancer
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Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-156308
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ADC Linker
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Cancer
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Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-156391A
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PROTAC Linkers
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Cancer
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TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
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- HY-156391
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PROTAC Linkers
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Cancer
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TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
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- HY-156392
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PROTAC Linkers
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Cancer
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TCO4-PEG7-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG7-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
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- HY-W872575A
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PROTAC Linkers
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Cancer
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TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
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- HY-W872575
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PROTAC Linkers
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Cancer
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TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
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- HY-156322
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ADC Linker
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Cancer
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BCN-exo-PEG3-maleimide is an ADC Linker containing 3 PEG units. BCN-exo-PEG3-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which enables the further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-134734
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ADC Linker
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Cancer
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BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-156320
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ADC Linker
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Cancer
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BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-W800817
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Biochemical Assay Reagents
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Others
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TCO-PEG4-maleimide is a click chemistry building block containing a TCO moiety and a maleimide group. The maleimide group will react with a thiol group to form a covalent bond. TCO moiety is very reactive with tetrazine (3rd generation click chemistry).
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- HY-168938
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Biochemical Assay Reagents
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Others
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Poly(ethylene glycol) methyl ether maleimide (Mn 2000) is a polyethylene glycol containing Maleimide (HY-W007324). Due to the Maleimide functional group, Poly(ethylene glycol) methyl ether maleimide (Mn 2000) can be used to conjugate biomolecules containing thiol groups.
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- HY-151696
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ADC Linker
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Others
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TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) .
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- HY-D0152
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Fluorescent Dye
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Others
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Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time .
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- HY-D2498
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Fluorescent Dye
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Others
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Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .
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- HY-156311
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ADC Linker
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Cancer
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BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-W016550
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CHMI; NCMI; NSC 524431
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Biochemical Assay Reagents
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Others
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N-Cyclohexylmaleimide is a compound containing a maleimide group, and this maleimide group can react with NHS ester.
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- HY-W879049
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DBCO-NHCO-PEG3-maleimide
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Biochemical Assay Reagents
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Others
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DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
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- HY-W879036
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Biochemical Assay Reagents
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Others
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DBCO-PEG8-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG8-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
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- HY-157008
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ADC Linker
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Cancer
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(S)-TCO-PEG2-Maleimide is an ADC linker containing 2 PEG units. (S)-TCO-PEG2-Maleimide can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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- HY-W087027
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- HY-D0103
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Fluorescent Dye
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Fluorescein diacetate 5-maleimide is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
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- HY-157977
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Radionuclide-Drug Conjugates (RDCs)
Biochemical Assay Reagents
MMP
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Cancer
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DOTA-GA-maleimide is a bifunctional chelator containing a DOTA macrocycle chelator, a GA linker, and a maleimide reactive group. DOTA-GA-maleimide can achieve radiolabeling of proteins by forming a stable coordination complex between the DOTA macrocycle and radioactive metal ions (such as 111In) through the specific binding of maleimide to protein thiol groups. DOTA-GA-maleimide can be used for SPECT imaging studies of MMP activity-related cancers .
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- HY-133399
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PROTAC Linkers
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Cancer
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Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W441009E
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Liposome
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Others
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DSPE-PEG-Maleimide (MW 20000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 20000) ammonium can be used in drug delivery research .
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- HY-W441009A
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Liposome
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Others
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DSPE-PEG-Maleimide (MW 3400) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 3400) ammonium can be used in drug delivery research .
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- HY-W441009C
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Liposome
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Others
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DSPE-PEG-Maleimide (MW 4000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 4000) ammonium can be used in drug delivery research .
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- HY-W441009B
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Liposome
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Others
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DSPE-PEG-Maleimide (MW 1000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 1000) ammonium can be used in drug delivery research .
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- HY-W441009H
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Liposome
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Others
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DSPE-PEG-Maleimide (MW 40000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 40000) ammonium can be used in drug delivery research .
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- HY-171561
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Biochemical Assay Reagents
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Others
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DOTAM-Maleimide triTFA is a bifunctional chelator, combining the DOTAM structure with a maleimide group for efficient thiol coupling. DOTAM-Maleimide triTFA forms stable complexes with radiometals, promising for applications in molecular imaging and radiotherapy .
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- HY-W441009D
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Liposome
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Others
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DSPE-PEG-Maleimide (MW 10000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 10000) ammonium can be used in drug delivery research .
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- HY-D2187
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Fluorescent Dye
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Others
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6-TAMRA maleimide is a fluorescent dye composed of the fluorescent group of an avidin derivative and a maleimide group.
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- HY-133475
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PROTAC Linkers
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Cancer
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TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-133372
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PROTAC Linkers
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Cancer
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DBCO-NHCO-PEG2-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140307
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PROTAC Linkers
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Cancer
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Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-133374
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PROTAC Linkers
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Cancer
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DBCO-NHCO-PEG12-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG12-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-133373
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PROTAC Linkers
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Cancer
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DBCO-NHCO-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-120770
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ADC Linker
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Cancer
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DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-141278
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-133468
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG6-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1340
-
|
|
Fluorescent Dye
|
|
|
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
|
-
- HY-W1048661E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG-maleimide (MW 2000) is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG-maleimide (MW 2000) anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG-maleimide (MW 3400) is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG-maleimide (MW 3400) anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG-maleimide (MW 5000) is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG-maleimide (MW 5000) anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG-maleimide (MW 1000) is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG-maleimide (MW 1000) anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-140307A
-
|
|
PROTAC Linkers
|
Others
|
|
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide (TEA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133477
-
|
|
PROTAC Linkers
|
Cancer
|
|
(S)-TCO-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . (S)-TCO-PEG3-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-141184
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-171561G
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOTAM-Maleimide triTFA (GMP) is DOTAM-Maleimide triTFA (HY-171561) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAM-Maleimide triTFA is a bifunctional chelator .
|
-
- HY-W800787
-
|
|
Liposome
|
Cancer
|
|
18:1 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a maleimide group.
|
-
- HY-W800786
-
|
N-MCC-PE
|
Liposome
|
Cancer
|
|
16:0 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a maleimide group.
|
-
- HY-156488
-
-
- HY-131029
-
|
JF646, Maleimide
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-W800789
-
|
|
Liposome
|
Cancer
|
|
16:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.
|
-
- HY-A0023AS2
-
-
- HY-W097734
-
-
- HY-W800788
-
|
|
Liposome
|
Cancer
|
|
18:1 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a phenyl maleimide group.
|
-
- HY-D1566
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-156317
-
|
|
ADC Linker
|
Cancer
|
|
BCN-endo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-D2091
-
|
|
Fluorescent Dye
|
Others
|
|
PE-VF647 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. PE-VF647 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 665 nm.
|
-
- HY-W017588
-
-
- HY-174927E
-
|
DBCO-PEG-Mal (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 3400) (DBCO-PEG-Mal (MW 3400)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 3400) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927B
-
|
DBCO-PEG-Mal (MW 600)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 600) (DBCO-PEG-Mal (MW 600)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 600) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927A
-
|
DBCO-PEG-Mal (MW 400)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 400) (DBCO-PEG-Mal (MW 400)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 400) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927
-
|
DBCO-PEG-Mal (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 5000) (DBCO-PEG-Mal (MW 5000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 5000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927D
-
|
DBCO-PEG-Mal (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 2000) (DBCO-PEG-Mal (MW 2000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 2000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927C
-
|
DBCO-PEG-Mal (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 1000) (DBCO-PEG-Mal (MW 1000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 1000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-D1925
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 425 Maleimide is a maleimide ester derivative of ATTO 425, which can be used to label proteins or antibodies. The maximum excitation emission wavelength: 439/489 nm.
|
-
- HY-D1918
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 390 maleimide is a maleimide ester derivative of ATTO 390, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 390/476 nm.
|
-
- HY-D2093
-
|
|
Fluorescent Dye
|
Others
|
|
PE-VF750 Maleimide is a thiol-reactive double-dye dye that contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/777 nm. PE-VF750 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 777 nm.
|
-
- HY-155640
-
|
|
Fluorescent Dye
|
Others
|
|
5-FAM maleimide is a 5-FAM (HY-66022) derivative. 5-FAM maleimide can be used to label proteins .
|
-
- HY-174921
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Maleimide-PEG-COOH (MW 1000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-D2150
-
|
|
Fluorescent Dye
|
Others
|
|
AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 maleimide contains maleimide groups that react with thiol groups to form covalent bonds. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-174921B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Maleimide-PEG-COOH (MW 3400) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-174921C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Maleimide-PEG-COOH (MW 5000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-174921A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Maleimide-PEG-COOH (MW 2000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-D2092
-
|
|
Fluorescent Dye
|
Others
|
|
PE-VF680 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/701 nm. PE-VF680 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 701 nm.
|
-
- HY-174885C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acrylate-PEG-Maleimide (MW 5000) is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
-
- HY-174885
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acrylate-PEG-Maleimide (MW 1000) is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
-
- HY-174885B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acrylate-PEG-Maleimide (MW 3400) is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
-
- HY-174885A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acrylate-PEG-Maleimide (MW 2000) is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
-
- HY-W738256
-
|
MDTPA
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Maleimide-DTPA (MDTPA) is a monoreactive DTPA derivative (MDTPA) with maleimide group as peptide binding site, which can be combined with radionuclides to prepare radionuclide conjugates (RDC). Maleimide-DTPA can chelate indium-111 (111In) and label peptides and peptides with indium-111. For example, it has high stability when combined with OST7 incubated in human serum, which is better than cyclic cDTPA. Maleimide-DTPA is a good material for medical imaging or treatment.
|
-
- HY-133540G
-
|
Maleimido-mono-amide-DOTA
|
ADC Linker
|
Inflammation/Immunology
Cancer
|
|
Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D1546
-
|
|
Fluorescent Dye
|
Cancer
|
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
|
-
- HY-D1961
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 maleimide is a maleimide derivative of ATTO 565, which can be used to label proteins or antibodies.
|
-
- HY-D2002
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 488 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 maleimide is a maleimide derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
- HY-D2047
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 532 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 maleimide is a maleimide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
-
- HY-D2063
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
|
-
- HY-D1933
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 590 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 maleimide is a maleimide derivative of ATTO 590, which can be used to label proteins or antibodies.
|
-
- HY-D2059
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 700 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 maleimide is a maleimide derivative of ATTO 700, which can be used to label proteins or antibodies.
|
-
- HY-D2074
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 680 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 maleimide is a maleimide derivative of ATTO 680, which can be used to label proteins or antibodies.
|
-
- HY-D2021
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 550 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 maleimide is a maleimide derivative of ATTO 550, which can be used to label proteins or antibodies.
|
-
- HY-W087027A
-
-
- HY-W808757
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-maleimide is a biotinylated biochemical assay reagent, which can be used as a thiol-specific probe. Biotin-maleimide can also be used to prepare the biotin-conjugated polychelating agent .
|
-
- HY-D1871
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1618
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 maleimide tetrafluoroborate is a specific labeling reagent for sulfhydryl groups with the λex of 550 nm and λem of 580 nm. Cyanine3 maleimide tetrafluoroborate can be used for protein and peptide labeling .
|
-
- HY-148549
-
-
- HY-174941
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG18-acid is a PEG derivative modified with maleimide groups. Maleimide is a functional group that can undergo Michael addition reaction with sulfhydryl (–SH) groups and can be used for bioconjugation.
|
-
- HY-D2231
-
|
|
ADC Payload
|
Others
|
|
Cy3.5 maleimide is a relatively water-soluble fluorescent dye. Cy3.5 maleimide is soluble in organic solvents, including DMF, DMSO and acetonitrile and so on .
|
-
- HY-114350
-
|
|
Fluorescent Dye
|
Others
|
|
BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy .
|
-
- HY-D1869
-
|
|
Fluorescent Dye
|
Others
|
|
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .
|
-
- HY-W440718C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Mal (MW 10000) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W440718A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Mal (MW 400) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W440718B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Mal (MW 600) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-D2249
-
-
- HY-46225
-
|
|
Others
|
Inflammation/Immunology
|
|
DEX-maleimide is a coupling agent that can be used to synthesize conjugates containing single-domain antibodies (VHH) conjugated with antigens and anti-inflammatory agents. DEX-maleimide can be used for research on autoimmune diseases .
|
-
- HY-174953D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG-Mal (MW 10000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG-Mal (MW 2000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG-Mal (MW 1000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG-Mal (MW 3400) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG-Mal (MW 5000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W007324
-
|
|
ADC Linker
Biochemical Assay Reagents
|
Cancer
|
|
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
|
-
- HY-D2181
-
|
|
Fluorescent Dye
|
Others
|
|
Preactivated PE-Cy5.5 Maleimide is a Preactivated PE-Cy5.5 Maleimide, which is a dye that can be used to label molecules such as dye that can be used to label molecules such as antibodies .
|
-
- HY-W190746
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG1-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
|
-
- HY-D1362
-
|
|
Fluorescent Dye
|
Others
|
|
BDP 630/650 maleimide is a fluorophore which can be read on the Cyanine5 channel. BDP 630/650 maleimide is useful for fluorescence lifetime related measurements because of the long life time of the excited state .
|
-
- HY-W190755
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
|
-
- HY-W1048555B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-SCM (MW 3400) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 3400) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-SCM (MW 2000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 2000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-SCM (MW 10000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 10000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-161780
-
|
|
Drug-Linker Conjugates for ADC
CDK
|
Cancer
|
|
Maleimide-Val-Ala-PAB-SNS032 is a conjugate of ADC toxin and linker. SNS032 is an inhibitor for CDK, inhibiting the cell cycle at G1/S phase and cell viability of cancer cells. Maleimide-Val-Ala-PAB is a cleavable ADC linker. Maleimide-Val-Ala-PAB-SNS032 can be utilized for the synthesis of ADC molecules .
|
-
- HY-W1048555H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-SCM (MW 40000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 40000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-SCM (MW 5000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 5000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-SCM (MW 20000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 20000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-SCM (MW 1000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 1000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W068119A
-
|
2-Maleimidoethylamine hydrochloride
|
Biochemical Assay Reagents
|
Cancer
|
|
N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a cross-linker. N-(2-Aminoethyl)maleimide hydrochloride can be used to prepare MMP-2 sensitive nanosystem, and for cancer research .
|
-
- HY-W585396
-
|
|
Fluorescent Dye
|
Others
|
|
BDP TR maleimide is a linker of BDP TR dye which is commonly used for microscopy and fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5.
|
-
- HY-W011692
-
-
- HY-D2090
-
-
- HY-D2094
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
Cancer
|
|
PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
|
-
- HY-D1527
-
|
|
Fluorescent Dye
|
Others
|
|
N-(3-Fluoranthyl)maleimide is a thiol fluorescent probe with a lifetime of 20 nsec. N-(3-Fluoranthyl)maleimide has a maximum excitation wavelength of 370 nm and can be used to study the time-dependent processes of biopolymers .
|
-
- HY-165929
-
-
- HY-165935
-
-
- HY-166990
-
-
- HY-W278706
-
|
|
Fluorescent Dye
|
Others
|
|
N-[4-(2-Benzimidazolyl)phenyl]maleimide is a potent fluorescent probe with excitation maximum of 315 nm and emission maximum of 360 nm. N-[4-(2-Benzimidazolyl)phenyl]maleimide can be used for fluorometry of thiol compounds .
|
-
![N-[4-(2-Benzimidazolyl)phenyl]maleimide](//file.medchemexpress.eu/product_pic/hy-w278706.gif)
- HY-W591975
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Alkyne maleimide is a bifunctional linker reagent with a terminal malimide group and a propargyl group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
|
-
- HY-W1048553C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-NH2 TFA (MW 5000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-NH2 TFA (MW 40000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-NH2 TFA (MW 2000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-NH2 TFA (MW 3400) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-NH2 TFA (MW 20000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-NH2 TFA (MW 1000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-NH2 TFA (MW 10000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-174961C
-
|
Fmoc-NH-PEG-Mal (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PEG-Maleimide (MW 5000) (Fmoc-NH-PEG-Mal (MW 5000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174961B
-
|
Fmoc-NH-PEG-Mal (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PEG-Maleimide (MW 3400) (Fmoc-NH-PEG-Mal (MW 3400)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174961
-
|
Fmoc-NH-PEG-Mal (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PEG-Maleimide (MW 1000) (Fmoc-NH-PEG-Mal (MW 1000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-163675
-
|
|
ADC Linker
|
Cancer
|
|
Maleimide-PEG8-Val-Ala-PAB is an ADC linker composed of the cleavable Val-Ala-PAB (HY-125933) linker and the probe molecule Maleimide (HY-W007324). Maleimide-PEG8-Val-Ala-PAB can be used to connect Cetuximab (HY-P9905) monoclonal antibody and CDK inhibitor SNS-032 (HY-10008) to synthesize antibody-drug conjugates (ADCs) .
|
-
- HY-174961A
-
|
Fmoc-NH-PEG-Mal (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PEG-Maleimide (MW 2000) (Fmoc-NH-PEG-Mal (MW 2000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-116270
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136104
-
|
|
ADC Linker
|
Cancer
|
|
Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-167036C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG-Mal (MW 5000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 5000) can be used for drug delivery .
|
-
- HY-167036A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG-Mal (MW 1000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 1000) can be used for drug delivery .
|
-
- HY-167036D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG-Mal (MW 10000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 10000) can be used for drug delivery .
|
-
- HY-157920
-
|
N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
|
-
- HY-167036B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG-Mal (MW 3400) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 3400) can be used for drug delivery .
|
-
- HY-133540
-
-
- HY-D1654
-
|
|
Fluorescent Dye
|
Others
|
|
BDP 581/591 maleimide is a linker of the BDP 581/591 dye. It has a long fluorescence lifetime and can be used for fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5, for the labeling of sulfhydryl groups of proteins and peptides.
|
-
- HY-W590586
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG4-NH-Boc is a PEG linker containing a maleimide group and a Boc protected amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond.
|
-
- HY-W800803
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5-NH-Boc is a PEG linker containing a maleimide group and a Boc protected amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond.
|
-
- HY-166648
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Maleimide (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-PEG-Maleimide (MW 2000)can be used in drug delivery research .
|
-
- HY-D1600
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
|
-
- HY-166990B
-
|
MeO-PEG-Mal (MW 2000)
|
Biochemical Assay Reagents
|
|
|
Methoxypolyethylene glycol maleimide (MW 2000) (MeO-PEG-Mal (MW 2000)) is a biochemical reagent .
|
-
- HY-166990C
-
|
MeO-PEG-Mal (MW 750)
|
Biochemical Assay Reagents
|
|
|
Methoxypolyethylene glycol maleimide (MW 750) (MeO-PEG-Mal (MW 750)) is a biochemical reagent .
|
-
- HY-166990A
-
|
MeO-PEG-Mal (MW 10000)
|
Biochemical Assay Reagents
|
|
|
Methoxypolyethylene glycol maleimide (MW 10000) (MeO-PEG-Mal (MW 10000)) is a biochemical reagent .
|
-
- HY-136562
-
|
|
MAGL
|
Metabolic Disease
|
|
N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM .
|
-
- HY-W190924
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG8-Val-Gly is an ADC linker containing a maleimide group.
|
-
- HY-W591618D
-
|
4-Arm-PEG-Mal (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-Maleimide (MW 3400) (4-Arm-PEG-Mal (MW 3400)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W591618B
-
|
4-Arm-PEG-Mal (MW 600)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-Maleimide (MW 600) (4-Arm-PEG-Mal (MW 600)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W591465
-
|
4-Arm-PEG-Mal (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-Maleimide (MW 2000) (4-Arm-PEG-Mal (MW 2000)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W591618A
-
|
4-Arm-PEG-Mal (MW 400)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-Maleimide (MW 400) (4-Arm-PEG-Mal (MW 400)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W591618C
-
|
4-Arm-PEG-Mal (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-Maleimide (MW 1000) (4-Arm-PEG-Mal (MW 1000)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-167834
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Farinomalein A is a maleimide that can be isolated from Paecilomyces farinosus. Farinomalein A has potent inhibition of Phytophtora sojae .
|
-
- HY-128925
-
AMAS
1 Publications Verification
|
ADC Linker
|
Cancer
|
|
AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.
|
-
- HY-163790
-
|
|
PROTAC Linkers
|
Others
|
|
Desthiobiotin-PEG3-sulfo-Maleimide is a PEG linker can be used in the synthesis of PROTACs .
|
-
- HY-D1526
-
|
|
Fluorescent Dye
|
Others
|
|
N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm .
|
-
- HY-172505
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG12-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W800654
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-163789
-
|
|
ADC Linker
|
Cancer
|
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-W190922
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG4-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-130908
-
|
|
Biochemical Assay Reagents
|
Others
|
|
11-Maleimidoundecanoic acid is an intermediate for ester and amide linked maleimide monomers. 11-Maleimidoundecanoic acid can be used to generate copolymers .
|
-
- HY-W009037
-
|
|
PROTAC Linkers
|
Cancer
|
|
Maleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-159783
-
-
- HY-42359
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-131023
-
|
JF549, Maleimide TFA
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-172721
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3B maleimide is a mono-reactive dye containing maleimide group, which can selectively and efficiently attach Cyanine3 fluorophore (an analog of Cy3) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cy3B is an improved version of Cy3 dyes with significantly increased fluorescence quantum yield and photostability.
|
-
- HY-126506
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-PFP ester is a nonclaevable ADC linker containing a Maleimide group, 4-unit PEG and a PFP ester.
|
-
- HY-130085
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.
|
-
- HY-126504
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester.
|
-
- HY-172291
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker featuring a maleimide, a PEG spacer, a Val-Cit dipeptide, a PAB. and a PNP carbonate. Maleimide is a thiol-specific covalent linker which is used to label cysteine residues in proteins while the PNP group acts as a highly activated leaving group. Val-Cit linkers are cleaved by cytoplasmic peptidases.
|
-
- HY-152919
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure.
|
-
- HY-D2309
-
|
|
Fluorescent Dye
|
Others
|
|
IRDye700Dx (IRDye 700DX NHS ester) Maleimide is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
|
-
- HY-W011433
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-(1-Pyrenyl)maleimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W800670
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-amido-PEG5-alkyne is a PEG linker containing a maleimide group and an alkyne. The hydrophilic PEG spacer increases solubility in aqueous media. The alkyne group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-130084
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG2-VCP-NB is a claevable ADC linker containing a Maleimide group, 2-unit PEG and a VCP NB.
|
-
- HY-D1936
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 465 Maleimid is a maleimide ester derivative of ATTO 465, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 453/506 nm.
|
-
- HY-D1960
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 633 Maleimid is a maleimide ester derivative of ATTO 633, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-D1976
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 610 Maleimid is a maleimide ester derivative of ATTO 610, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 616/633 nm.
|
-
- HY-D1982
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 725 Maleimid is a maleimide ester derivative of ATTO 725, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
|
-
- HY-D1744
-
|
|
Fluorescent Dye
|
Others
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
|
-
- HY-D1948
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 Maleimid is a maleimide ester derivative of ATTO 594, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 603/626 nm.
|
-
- HY-46398
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Val-Phe-Boc is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Val-Phe-Boc can be used in the synthesis of the Deruxtecan .
|
-
- HY-D2020
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 665 maleimid is a maleimide ester derivative of ATTO 665, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 663/680 nm.
|
-
- HY-D2028
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 514 maleimid is a maleimide ester derivative of ATTO 514, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 511/531 nm.
|
-
- HY-W190927
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MC-Val-Cit-Doxorubicin is drug-linker conjugate for ADC. The maleimide can conjugate with thiol containing molecules. Doxorubicin is an anthracycline antibiotic with antineoplastic activity
|
-
- HY-D1986
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 620 Maleimid is a maleimide ester derivative of ATTO 620, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 620/642 nm.
|
-
- HY-D1994
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 647 Maleimid is a maleimide ester derivative of ATTO 647, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-155902D
-
|
Maleimide-PEG-Hydroxy (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 10000) (Maleimide-PEG-Hydroxy (MW 10000)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 10000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-155902E
-
|
Maleimide-PEG-Hydroxy (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 20000) (Maleimide-PEG-Hydroxy (MW 20000)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 20000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-155902H
-
|
Maleimide-PEG-Hydroxy (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 40000) (Maleimide-PEG-Hydroxy (MW 40000)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 40000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-155902C
-
|
Maleimide-PEG-Hydroxy (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 3400) (Maleimide-PEG-Hydroxy (MW 3400)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 3400) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-136097
-
|
|
ADC Linker
|
Cancer
|
|
Maleimide-PEG2-hydrazide (TFA) is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D0975
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
|
-
- HY-160981
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VCP-NB (Compound 17) is a degradable ADC linker containing a maleimide group, 4 PEG units and VCP NB .
|
-
- HY-W144703
-
|
9-Aminoheptadecane
|
Biochemical Assay Reagents
|
Others
|
|
Heptadecan-9-amine (9-Aminoheptadecane) is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains.
|
-
- HY-W800719
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-N'-(PEG1-t-butyl ester)-L-Lysine-amido-Mal is the amino acid, lysine, with a maleimide at its C-terminus, a Boc-protecting group on its α-amine, and an amido-PEG1-t-butyl ester on its ε-amine. Maleimide is a thiol-reactive covalent group used to conjugate cysteine residues, while the Boc and the t-butyl ester can be later deprotected to perform further reactions.
|
-
- HY-W800648
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG2-Amide is a PEG linker with a maleimide group which can react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W1049129D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-mal (MW 40000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 40000) can be used for drug delivery .
|
-
- HY-W1048552
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-mal (MW 1000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 1000) can be used for drug delivery .
|
-
- HY-W1049129C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-mal (MW 20000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 20000) can be used for drug delivery .
|
-
- HY-174914
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG4-mal is a PEG derivative composed of Biotin, 4 PEG units and Maleimide. Biotin can form a stable non-covalent bond with streptavidin.
|
-
- HY-W1049129B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-mal (MW 10000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 10000) can be used for drug delivery .
|
-
- HY-D2239
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3.5 maleimide is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
|
-
- HY-D2763
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
|
-
- HY-129655
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent which contains N-hydroxysuccinimide (NHS) ester and maleimide groups, allowing covalent conjugation of amine- and sulfhydryl-containing molecules .
|
-
- HY-W020780C
-
|
mPEG-Maleimide (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Mal (MW 3400) is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-W020780A
-
|
mPEG-Maleimide (MW 350)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Mal (MW 350) is a PEG derivative used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-W020780B
-
|
mPEG-Maleimide (MW 750)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Mal (MW 750) is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-160982
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG3-VCP-NB (Compund 25c) is a degradable ADC linker containing a maleimide group, 3-unit PEG and VCP NB .
|
-
- HY-126669
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VA is used for making antibody-drug conjugate.
|
-
- HY-W800679
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-Cyclohexyl-PEG3-Biotin is a PEG linker containing a maleimide moiety and a biotin group. Maleimides react specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The biotinylation can react with amine molecules in the presence of activator EDC or HATU. PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein. The PEG moiety also increases solubility of Biotin-PEG conjugates considerably.
|
-
- HY-129526
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate .
|
-
- HY-126668A
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VC-PAB-DMEA TFA is a degradable ADC linker containing a maleimide group and can be used to synthesize antibody conjugate active molecules (ADCs) .
|
-
- HY-171508
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Mal-PNU-159682 is a Drug-Linker Conjugates for ADC, composes of ADC linker (maleimide) and ADC cytotoxin PNU-159682 (HY-16700), and has anti-tumor activity .
|
-
- HY-137251
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo-MBS sodium is a heterobifunctional crosslinker with a maleimide group and an N-hydroxysuccinimide (NHS) ester group, which can react with cysteine residues and lysine residues on proteins. Sulfo-MBS sodium be used for protein cross-linking studies .
|
-
- HY-156518
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Glucose-malemide is a glycoconjugate consisting of a glucose molecule and a maleimide group of a linker molecule. Glucose-malemide can be used in the preparation of glucose-responsive insulin delivery compositions, thereby conjugating glucose to insulin .
|
-
- HY-D0151
-
|
|
Fluorescent Dye
|
Others
|
|
Tetramethylrhodamine-5-maleimide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-121030
-
|
N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide
|
Fluorescent Dye
|
Others
|
|
DACM (N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide) is a thiol-directed fluorescent dye (Ex=396 nm, Em=468 nm) .
|
-
- HY-W395122
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG1-PNP-carbonate is a amine-reactive compound. PNP is a good leaving group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-175218
-
|
|
ADC Linker
|
Cancer
|
|
Maleimide-Ph(3,5-F)-PEG4-Val-Ala is a cleavable PEG-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130818
-
|
|
ADC Linker
|
Cancer
|
|
N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) ) .
|
-
- HY-W590555
-
|
|
Liposome
|
Cancer
|
|
Thiol-PEG-DMG, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
|
-
- HY-W440722
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
Cholesterol-PEG-Thiol (MW 1000) is a PEGylated lipid that forms micelles in water and can be used to prepare liposomes or nanoparticles as drug delivery systems. The thiol moiety reacts with maleimide to form a stable thioether bond .
|
-
- HY-W440719
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-MAL (MW 2000) is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
|
-
- HY-174279
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MCC-AAQ-Exa is a drug-linker conjugates for ADC, obtained by condensing the linker with Exatecan (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs). MCC is an ADC linker containing a maleimide fragment .
|
-
- HY-W615173
-
|
|
Biochemical Assay Reagents
|
Others
|
|
NHS ester-C2-NHCO-C2-NHS is a heterobifunctional PEG linker, featuring a terminal NHS ester that can be used to label amine compounds and maleimide group for reactions with thiol groups.
|
-
- HY-W190796
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG3-NH2 is a linear heterobifunctional PEG reagent with a maleimide and an amine. Mal-PEG3-NH2 is a useful crosslinking reagent with a PEG spacer .
|
-
- HY-W440724
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Thiol (MW 3400) is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
|
-
- HY-W1048605
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-Mal (MW 5000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 5000) can be used for drug delivery .
|
-
- HY-W1048605C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-Mal (MW 40000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 40000) can be used for drug delivery .
|
-
- HY-126671
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Phe-C4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB is used for making antibody-drug conjugate.
|
-
- HY-W1048510B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-Mal (MW 20000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 20000) can be used for drug delivery .
|
-
- HY-W1048510A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-Mal (MW 10000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 10000) can be used for drug delivery .
|
-
- HY-126668
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VC-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VC-PAB-DMEA is used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W1048510C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-Mal (MW 40000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 40000) can be used for drug delivery .
|
-
- HY-W1048510D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-Mal (MW 5000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 5000) can be used for drug delivery .
|
-
- HY-W1048605B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-Mal (MW 10000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 10000) can be used for drug delivery .
|
-
- HY-W1048605A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-Mal (MW 20000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 20000) can be used for drug delivery .
|
-
- HY-126672
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-Val-Cit-PAB is used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-155901
-
|
Maleimide-NH-PEG-amine TFA (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-NH-PEG-NH2 (TFA) (MW 2000) is a PEG derivative that may be used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-13631E
-
Deruxtecan
Maximum Cited Publications
19 Publications Verification
MC-GGFG-DXD
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
|
-
- HY-W440897
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-SH, MW 3400 is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA. Reagent grade, for research use only.
|
-
- HY-126674
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Phe-C4-Val-Cit-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB-DMEA is used for making antibody-drug conjugate.
|
-
- HY-108639
-
MIRA-1
2 Publications Verification
NSC 19630
|
MDM-2/p53
Apoptosis
|
Cancer
|
|
MIRA-1 is a maleimide analogue. MIRA-1 can induce apoptosis in mutant p53 cells via restoration of p53-dependent transcriptional transactivation. MIRA-1 has anticancer activity .
|
-
- HY-126673
-
|
|
ADC Linker
|
Cancer
|
|
Mal-C2-Gly3-EDA is a cleavable ADC linker containing a Maleimide group. Mal-C2-Gly3-EDA is used for making antibody-drug conjugate.
|
-
- HY-W441007
-
|
|
Liposome
|
Inflammation/Immunology
Cancer
|
|
DSPE-MAL is a phospholipid compound with a maleimide reactive group. DSPE-MAL contains two saturated fatty acids and can self-assemble in water to form a lipid bilayer. DSPE-MAL can be used to prepare liposomes as nanocarriers for active molecules .
|
-
- HY-W440896
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
|
-
- HY-D2800
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG-MAL (MW 400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 400) can be used for fluorescent labeling and imaging .
|
-
- HY-D2800B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG-MAL (MW 3400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 3400) can be used for fluorescent labeling and imaging .
|
-
- HY-W040289
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-D2800C
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG-MAL (MW 5000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 5000) can be used for fluorescent labeling and imaging .
|
-
- HY-D2800A
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG-MAL (MW 1000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 1000) can be used for fluorescent labeling and imaging .
|
-
- HY-D2800D
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG-MAL (MW 10000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 10000) can be used for fluorescent labeling and imaging .
|
-
- HY-174809A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-Mal (MW 600) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174809E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-Mal (MW 5000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174809H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-Mal (MW 10000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-D2373
-
|
|
Fluorescent Dye
|
Others
|
|
CY5.5-PEG2000-Mal is used for preparing fluorescently labeled molecules. It is formed by condensing maleimide groups (Mal), PEG2000, and fluorescent dye CY5.5 (HY-D0924) .
|
-
- HY-174809
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-Mal (MW 400) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-D2374
-
|
|
Fluorescent Dye
|
Others
|
|
CY5.5-PEG5000-Mal is used for preparing fluorescently labeled molecules. It is formed by condensing maleimide groups (Mal), PEG5000, and fluorescent dye CY5.5 (HY-D0924) .
|
-
- HY-174809C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-Mal (MW 2000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174809D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-Mal (MW 3400) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174809B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-Mal (MW 1000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W190796A
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG3-NH2 TFA is a linear heterobifunctional PEG crosslinker with Maleimide (HY-W007324) and amine. Mal-PEG3-NH2 TFA is a non-degradable (non-cleavable) PROTAC linker .
|
-
- HY-D2497
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-145674
-
|
|
DNA/RNA Synthesis
ADC Payload
|
Cancer
|
|
HDP 30.1699, the derivative of α-Amanitin, shows considerable cross-links. The cysteine residues of the anti-HER2 THIOMAB antibody are used for conjugation of the cysteine reactive linker–Amanitin compound, HDP 30.1699, with a cleavable linker by maleimide chemistry .
|
-
- HY-126507
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG1-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules
|
-
- HY-D2381
-
|
|
Fluorescent Dye
|
Others
|
|
AF 488 maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach AF 488 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-126509
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-126508
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules
|
-
- HY-13631ES4
-
-
- HY-148459
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate .
|
-
- HY-W588728
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W588736
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-13631ES
-
-
- HY-13631ES3
-
|
MC-GGFG-DXD-d2
|
Drug-Linker Conjugates for ADC
Isotope-Labeled Compounds
|
Others
|
|
Deruxtecan-d2 is the deuterium labeled Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
- HY-W800805
-
|
|
Liposome
|
Cancer
|
|
DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
|
-
- HY-46346
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Gly-NH-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-NH-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
|
-
- HY-13631ES2
-
|
MC-GGFG-DXD-d4-1
|
Drug-Linker Conjugates for ADC
Isotope-Labeled Compounds
|
Others
|
|
Deruxtecan-d4-1 is the deuterium labeled Adenosine Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
- HY-149117
-
|
|
Fluorescent Dye
|
Others
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-W1048849A
-
|
4-Arm PEG-thiol (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG-SH (MW 5000) (4-Arm PEG-thiol (MW 5000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-W1048849D
-
|
4-Arm PEG-thiol (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG-SH (MW 40000) (4-Arm PEG-thiol (MW 40000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-D2883E
-
|
Rhodamine B-PEG-SH (MW 5000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 5000) (Rhodamine B-PEG-SH (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883B
-
|
Rhodamine B-PEG-SH (MW 1000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 1000) (Rhodamine B-PEG-SH (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883C
-
|
Rhodamine B-PEG-SH (MW 2000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 2000) (Rhodamine B-PEG-SH (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883H
-
|
Rhodamine B-PEG-SH (MW 10000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 10000) (Rhodamine B-PEG-SH (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883D
-
|
Rhodamine B-PEG-SH (MW 3400)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 3400) (Rhodamine B-PEG-SH (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-164088
-
-
- HY-W1048849C
-
|
4-Arm PEG-thiol (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG-SH (MW 20000) (4-Arm PEG-thiol (MW 20000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-D2883A
-
|
Rhodamine B-PEG-SH (MW 600)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 4600) (Rhodamine B-PEG-SH (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-W1048849B
-
|
4-Arm PEG-thiol (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG-SH (MW 10000) (4-Arm PEG-thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-D2883
-
|
Rhodamine B-PEG-SH (MW 400)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 400) (Rhodamine B-PEG-SH (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-45669
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
|
-
- HY-D2885B
-
|
Rhodamine B-PEG-Mal (MW 1000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-Mal (MW 1000) (Rhodamine B-PEG-Mal (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 1000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-49453
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
|
-
- HY-D2530
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2532
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2529
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-SH (MW 2000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2885H
-
|
Rhodamine B-PEG-Mal (MW 10000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-Mal (MW 10000) (Rhodamine B-PEG-Mal (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 10000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2885E
-
|
Rhodamine B-PEG-Mal (MW 5000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-Mal (MW 5000) (Rhodamine B-PEG-Mal (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 5000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2509
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2531
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2885
-
|
Rhodamine B-PEG-Mal (MW 400)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-Mal (MW 400) (Rhodamine B-PEG-Mal (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 400) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2885A
-
|
Rhodamine B-PEG-Mal (MW 600)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-Mal (MW 600) (Rhodamine B-PEG-Mal (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 600) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2885C
-
|
Rhodamine B-PEG-Mal (MW 2000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-Mal (MW 2000) (Rhodamine B-PEG-Mal (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 2000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2885D
-
|
Rhodamine B-PEG-Mal (MW 3400)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-Mal (MW 3400) (Rhodamine B-PEG-Mal (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 3400) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2512
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2556
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2557
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2559
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2558
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2589
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).
|
-
- HY-W800722
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-(PEG1-acid)-L-Lysine-amido-Mal is a PEG based linker with terminal malimide and carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
|
-
- HY-W591479
-
|
|
ADC Linker
|
Cancer
|
|
MC-Val-Ala-NHS ester is a cleavable ADC linker with a malimide group and an NHS ester group. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide group is reactive toward thiol groups. MC is reactive with thiol moieties. The NHS ester is able to react specifically and efficiently with amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond.
|
-
- HY-W1048545I
-
|
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG-SH (MW 3400) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 3400) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-W1048545A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG-SH (MW 2000) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 2000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-W1048545C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG-SH (MW 5000) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 5000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-173639
-
|
|
Antibody-Drug Conjugates (ADCs)
Topoisomerase
|
Cancer
|
|
AZD0516 is a first-in-class antibody-drug conjugate (ADC) targeting six-transmembrane epithelial antigen of the prostate-2 (STEAP2). The anti-STEAP2 monoclonal antibody (mAb) is conjugated via interchain cysteines to a maleimide-reactive, β-glucuronidase-cleavable linker (HY-173635) bearing the topoisomerase 1 inhibitor, Exatecan (HY-13631). AZD0516 can be used for the study of prostate cancer .
|
-
- HY-W1048545H
-
|
Amine-PEG-Thiol (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG-SH (MW 1000) (Amine-PEG-Thiol (MW 1000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 1000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-W1048545E
-
|
Amine-PEG-Thiol (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG-SH (MW 20000) (Amine-PEG-Thiol (MW 20000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 20000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-W1048545D
-
|
Amine-PEG-Thiol (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG-SH (MW 10000) (Amine-PEG-Thiol (MW 10000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 10000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-13631EG
-
|
MC-GGFG-DXD
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
|
-
- HY-W1048545J
-
|
Amine-PEG-Thiol (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG-SH (MW 40000) (Amine-PEG-Thiol (MW 40000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 40000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-143218
-
|
Tetraphenylethene maleimide
|
Huntingtin
Parasite
|
Infection
Neurological Disease
|
|
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
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-
- HY-118112
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
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-
- HY-173635
-
|
|
ADC Linker
|
Cancer
|
|
Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB is an interchain cysteines to a Maleimide-reactive, β-glucuronidase-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as AZD0516 (HY-173639) .
|
-
![Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB](//file.medchemexpress.eu/product_pic/hy-173635.gif)
- HY-113914
-
|
Elraglusib
|
GSK-3
Apoptosis
Autophagy
|
Cancer
|
|
9-ING-41 (Elraglusib) is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 0.71 μM. 9-ING-41 significantly leads to cell cycle arrest, autophagy and apoptosis in cancer cells. 9-ING-41 has anticancer activity and has the potential for enhancing the antitumor effects of chemotherapeutic agents .
|
-
- HY-138200
-
|
Cyanine5 maleimide
|
DNA Stain
Fluorescent Dye
|
Others
|
|
Cy5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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-
- HY-D1565
-
|
|
Fluorescent Dye
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Others
|
|
Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D1323
-
|
Cy5.5 maleimide chloride
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-153360
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
MC-GGFG-AM-(10Me-11F-Camptothecin) is a linker-payload conjugate used to synthesize ZW251. ZW251 an antibody-drug conjugate (ADC) targeting human GPC3. ZW251 consists of a humanized IgG1 antibody conjugated to a novel camptothecin-based topoisomerase 1 inhibitor, ZD06519, via a linker. The linker is the maleimide anchor and a glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) cleavable linker. ZW251 has high affinity with human and cynomolgus monkey GPC3. ZW251 displays rapid internalization in GPC3-expressing HCC cell lines, and bystander-mediated killing of GPC3 negative cancer cells .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W011618
-
|
|
Fluorescent Dyes/Probes
|
|
N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione .
|
-
- HY-D0069
-
|
|
Fluorescent Dyes/Probes
|
|
CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm) .
|
-
- HY-D0098
-
|
N-(5-Fluoresceinyl)maleimide
|
Fluorescent Dyes/Probes
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
|
-
- HY-W998680
-
|
5-FITC-Maleimide
|
Fluorescent Dyes/Probes
|
|
Fluorescein-maleimide is a fluorescein dye linker containing a maleimide group. The maleimides in Fluorescein-maleimide react with thiol-containing compounds or biomolecules to form thioester bonds between pH 6.5 and 7.5. Fluorescein-maleimide is specifically designed for fluorescent labeling of proteins, nucleic acids, or other molecules containing one or more thiol groups .
|
-
- HY-137098
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy3 maleimide potassium is a fluorescent dye with a maleimide functionality at the end a short alkyl linker. Sulfo-Cy3 maleimide potassium can be used for the labeling of antibodies and other labile proteins .
|
-
- HY-D2182
-
|
|
Fluorescent Dyes/Probes
|
|
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
-
- HY-D2180
-
|
|
Fluorescent Dyes/Probes
|
|
Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
-
- HY-D1363
-
|
|
Fluorescent Dyes/Probes
|
|
BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .
|
-
- HY-D2103
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA-PEG3-Maleimide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Maleimide contains maleimide groups that react with thiol groups to form covalent bonds.
|
-
- HY-D2104
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA-PEG7-Maleimide is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
|
-
- HY-W190932
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
|
-
- HY-D1592
-
|
|
Fluorescent Dyes/Probes
|
|
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .
|
-
- HY-D2488
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.
|
-
- HY-D0152
-
|
|
Fluorescent Dyes/Probes
|
|
Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time .
|
-
- HY-D2498
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .
|
-
- HY-D0103
-
|
|
Fluorescent Dyes/Probes
|
|
Fluorescein diacetate 5-maleimide is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
-
- HY-D2187
-
|
|
Dyes
|
|
6-TAMRA maleimide is a fluorescent dye composed of the fluorescent group of an avidin derivative and a maleimide group.
|
-
- HY-D1340
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
|
-
- HY-171561G
-
|
|
Fluorescent Dye
|
|
DOTAM-Maleimide triTFA (GMP) is DOTAM-Maleimide triTFA (HY-171561) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAM-Maleimide triTFA is a bifunctional chelator .
|
-
- HY-131029
-
|
JF646, Maleimide
|
Fluorescent Dyes/Probes
|
|
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D1566
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D2091
-
|
|
Protein Labeling
|
|
PE-VF647 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. PE-VF647 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 665 nm.
|
-
- HY-D1925
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 425 Maleimide is a maleimide ester derivative of ATTO 425, which can be used to label proteins or antibodies. The maximum excitation emission wavelength: 439/489 nm.
|
-
- HY-D1918
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 390 maleimide is a maleimide ester derivative of ATTO 390, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 390/476 nm.
|
-
- HY-D2093
-
|
|
Protein Labeling
|
|
PE-VF750 Maleimide is a thiol-reactive double-dye dye that contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/777 nm. PE-VF750 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 777 nm.
|
-
- HY-D2150
-
|
|
Fluorescent Dyes/Probes
|
|
AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 maleimide contains maleimide groups that react with thiol groups to form covalent bonds. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-D2092
-
|
|
Protein Labeling
|
|
PE-VF680 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/701 nm. PE-VF680 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 701 nm.
|
-
- HY-133540G
-
|
Maleimido-mono-amide-DOTA (GMP)
|
Fluorescent Dye
|
|
Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D1546
-
|
|
Fluorescent Dyes/Probes
|
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
|
-
- HY-D1961
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 565 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 maleimide is a maleimide derivative of ATTO 565, which can be used to label proteins or antibodies.
|
-
- HY-D2002
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 488 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 maleimide is a maleimide derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
- HY-D2047
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 532 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 maleimide is a maleimide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
-
- HY-D2063
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
|
-
- HY-D1933
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 590 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 maleimide is a maleimide derivative of ATTO 590, which can be used to label proteins or antibodies.
|
-
- HY-D2059
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 700 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 maleimide is a maleimide derivative of ATTO 700, which can be used to label proteins or antibodies.
|
-
- HY-D2074
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 680 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 maleimide is a maleimide derivative of ATTO 680, which can be used to label proteins or antibodies.
|
-
- HY-D2021
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 550 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 maleimide is a maleimide derivative of ATTO 550, which can be used to label proteins or antibodies.
|
-
- HY-D1871
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1618
-
|
|
Dyes
|
|
Cyanine3 maleimide tetrafluoroborate is a specific labeling reagent for sulfhydryl groups with the λex of 550 nm and λem of 580 nm. Cyanine3 maleimide tetrafluoroborate can be used for protein and peptide labeling .
|
-
- HY-D2231
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3.5 maleimide is a relatively water-soluble fluorescent dye. Cy3.5 maleimide is soluble in organic solvents, including DMF, DMSO and acetonitrile and so on .
|
-
- HY-114350
-
|
|
Fluorescent Dyes/Probes
|
|
BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy .
|
-
- HY-D1869
-
|
|
Fluorescent Dyes/Probes
|
|
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .
|
-
- HY-D2249
-
-
- HY-D2181
-
|
|
Fluorescent Dyes/Probes
|
|
Preactivated PE-Cy5.5 Maleimide is a Preactivated PE-Cy5.5 Maleimide, which is a dye that can be used to label molecules such as dye that can be used to label molecules such as antibodies .
|
-
- HY-D1362
-
|
|
Fluorescent Dyes/Probes
|
|
BDP 630/650 maleimide is a fluorophore which can be read on the Cyanine5 channel. BDP 630/650 maleimide is useful for fluorescence lifetime related measurements because of the long life time of the excited state .
|
-
- HY-W585396
-
|
|
Fluorescent Dyes/Probes
|
|
BDP TR maleimide is a linker of BDP TR dye which is commonly used for microscopy and fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5.
|
-
- HY-D2090
-
-
- HY-D2094
-
|
|
Protein Labeling
|
|
PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
|
-
- HY-D1527
-
|
|
Fluorescent Dyes/Probes
|
|
N-(3-Fluoranthyl)maleimide is a thiol fluorescent probe with a lifetime of 20 nsec. N-(3-Fluoranthyl)maleimide has a maximum excitation wavelength of 370 nm and can be used to study the time-dependent processes of biopolymers .
|
-
- HY-D1654
-
|
|
Fluorescent Dyes/Probes
|
|
BDP 581/591 maleimide is a linker of the BDP 581/591 dye. It has a long fluorescence lifetime and can be used for fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5, for the labeling of sulfhydryl groups of proteins and peptides.
|
- HY-D1600
-
|
|
Dyes
|
|
Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
|
- HY-D1526
-
|
|
Fluorescent Dyes/Probes
|
|
N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm .
|
- HY-131023
-
|
JF549, Maleimide TFA
|
Fluorescent Dyes/Probes
|
|
Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-172721
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3B maleimide is a mono-reactive dye containing maleimide group, which can selectively and efficiently attach Cyanine3 fluorophore (an analog of Cy3) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cy3B is an improved version of Cy3 dyes with significantly increased fluorescence quantum yield and photostability.
|
- HY-D2309
-
|
|
Dyes
|
|
IRDye700Dx (IRDye 700DX NHS ester) Maleimide is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
|
- HY-D1936
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 465 Maleimid is a maleimide ester derivative of ATTO 465, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 453/506 nm.
|
- HY-D1960
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 633 Maleimid is a maleimide ester derivative of ATTO 633, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
- HY-D1976
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 610 Maleimid is a maleimide ester derivative of ATTO 610, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 616/633 nm.
|
- HY-D1982
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 725 Maleimid is a maleimide ester derivative of ATTO 725, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
|
- HY-D1744
-
|
|
Fluorescent Dyes/Probes
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
|
- HY-D1948
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 594 Maleimid is a maleimide ester derivative of ATTO 594, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 603/626 nm.
|
- HY-D2020
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 665 maleimid is a maleimide ester derivative of ATTO 665, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 663/680 nm.
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- HY-D2028
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 514 maleimid is a maleimide ester derivative of ATTO 514, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 511/531 nm.
|
- HY-D1986
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 620 Maleimid is a maleimide ester derivative of ATTO 620, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 620/642 nm.
|
- HY-D1994
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 647 Maleimid is a maleimide ester derivative of ATTO 647, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
- HY-D2239
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy3.5 maleimide is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
|
- HY-D2763
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
|
- HY-D0151
-
|
|
Fluorescent Dyes/Probes
|
|
Tetramethylrhodamine-5-maleimide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-121030
-
|
N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide
|
Fluorescent Dyes/Probes
|
|
DACM (N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide) is a thiol-directed fluorescent dye (Ex=396 nm, Em=468 nm) .
|
- HY-D2800
-
|
|
Fluorescent Dyes/Probes
|
|
FITC-PEG-MAL (MW 400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 400) can be used for fluorescent labeling and imaging .
|
- HY-D2800B
-
|
|
Fluorescent Dyes/Probes
|
|
FITC-PEG-MAL (MW 3400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 3400) can be used for fluorescent labeling and imaging .
|
- HY-D2800C
-
|
|
Fluorescent Dyes/Probes
|
|
FITC-PEG-MAL (MW 5000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 5000) can be used for fluorescent labeling and imaging .
|
- HY-D2800A
-
|
|
Fluorescent Dyes/Probes
|
|
FITC-PEG-MAL (MW 1000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 1000) can be used for fluorescent labeling and imaging .
|
- HY-D2800D
-
|
|
Fluorescent Dyes/Probes
|
|
FITC-PEG-MAL (MW 10000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG-MAL (MW 10000) can be used for fluorescent labeling and imaging .
|
- HY-D2373
-
|
|
Dyes
|
|
CY5.5-PEG2000-Mal is used for preparing fluorescently labeled molecules. It is formed by condensing maleimide groups (Mal), PEG2000, and fluorescent dye CY5.5 (HY-D0924) .
|
- HY-D2374
-
|
|
Dyes
|
|
CY5.5-PEG5000-Mal is used for preparing fluorescently labeled molecules. It is formed by condensing maleimide groups (Mal), PEG5000, and fluorescent dye CY5.5 (HY-D0924) .
|
- HY-D2497
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
- HY-D2381
-
|
|
Fluorescent Dyes/Probes
|
|
AF 488 maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach AF 488 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
- HY-149117
-
|
|
Fluorescent Dyes/Probes
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
|
- HY-D2883E
-
|
Rhodamine B-PEG-SH (MW 5000)
|
Dyes
|
|
RB-PEG-SH (MW 5000) (Rhodamine B-PEG-SH (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
- HY-D2883B
-
|
Rhodamine B-PEG-SH (MW 1000)
|
Dyes
|
|
RB-PEG-SH (MW 1000) (Rhodamine B-PEG-SH (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
- HY-D2883C
-
|
Rhodamine B-PEG-SH (MW 2000)
|
Dyes
|
|
RB-PEG-SH (MW 2000) (Rhodamine B-PEG-SH (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
- HY-D2883H
-
|
Rhodamine B-PEG-SH (MW 10000)
|
Dyes
|
|
RB-PEG-SH (MW 10000) (Rhodamine B-PEG-SH (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
- HY-D2883D
-
|
Rhodamine B-PEG-SH (MW 3400)
|
Dyes
|
|
RB-PEG-SH (MW 3400) (Rhodamine B-PEG-SH (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
- HY-D2883A
-
|
Rhodamine B-PEG-SH (MW 600)
|
Dyes
|
|
RB-PEG-SH (MW 4600) (Rhodamine B-PEG-SH (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
- HY-D2883
-
|
Rhodamine B-PEG-SH (MW 400)
|
Dyes
|
|
RB-PEG-SH (MW 400) (Rhodamine B-PEG-SH (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
- HY-D2885B
-
|
Rhodamine B-PEG-Mal (MW 1000)
|
Dyes
|
|
RB-PEG-Mal (MW 1000) (Rhodamine B-PEG-Mal (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 1000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
- HY-D2530
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2532
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2529
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-SH (MW 2000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2885H
-
|
Rhodamine B-PEG-Mal (MW 10000)
|
Dyes
|
|
RB-PEG-Mal (MW 10000) (Rhodamine B-PEG-Mal (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 10000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
- HY-D2885E
-
|
Rhodamine B-PEG-Mal (MW 5000)
|
Dyes
|
|
RB-PEG-Mal (MW 5000) (Rhodamine B-PEG-Mal (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 5000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
- HY-D2509
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
- HY-D2531
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2885
-
|
Rhodamine B-PEG-Mal (MW 400)
|
Dyes
|
|
RB-PEG-Mal (MW 400) (Rhodamine B-PEG-Mal (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 400) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
- HY-D2885A
-
|
Rhodamine B-PEG-Mal (MW 600)
|
Dyes
|
|
RB-PEG-Mal (MW 600) (Rhodamine B-PEG-Mal (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 600) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
- HY-D2885C
-
|
Rhodamine B-PEG-Mal (MW 2000)
|
Dyes
|
|
RB-PEG-Mal (MW 2000) (Rhodamine B-PEG-Mal (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 2000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
- HY-D2885D
-
|
Rhodamine B-PEG-Mal (MW 3400)
|
Dyes
|
|
RB-PEG-Mal (MW 3400) (Rhodamine B-PEG-Mal (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG-Mal (MW 3400) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
- HY-D2512
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
- HY-D2556
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2557
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2559
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2558
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2589
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).
|
- HY-13631EG
-
|
MC-GGFG-DXD (GMP)
|
Fluorescent Dye
|
|
Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
|
- HY-143218
-
TPE-MI
Maximum Cited Publications
6 Publications Verification
Tetraphenylethene maleimide
|
Fluorescent Dyes/Probes
|
|
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
|
- HY-138200
-
|
Cyanine5 maleimide
|
Fluorescent Dyes/Probes
|
|
Cy5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D1565
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D1323
-
|
Cy5.5 maleimide chloride
|
Dyes
|
|
Cyanine5.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
| Cat. No. |
Product Name |
Type |
-
- HY-140740
-
|
|
Drug Delivery
|
|
DSPE-PEG-Maleimide, MW 5000 has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-maleimide extends blood circulation time and higher stability for encapsulated agents .
|
-
- HY-144004
-
|
DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
|
Drug Delivery
|
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
|
-
- HY-144004A
-
|
DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
|
-
- HY-140739
-
|
|
Drug Delivery
|
|
DSPE-PEG2000-Maleimide is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
|
-
- HY-D1364
-
|
|
Biochemical Assay Reagents
|
|
Pyrene maleimide is a polyaromatic fluorescent hydrocarbon with a termininal maleimide group. The maleimide group will react with a thiol group to form a covalent bond.
|
-
- HY-W441004
-
|
|
Drug Delivery
|
|
DSPE-Thiol is a phophalipid capped with thiol group. The thiol capped head can selectively react with maleimide. DSPE-Thiol can also be used for the preparation of phospholipid dimers .
|
-
- HY-159674
-
|
N-Tetamine-polySarcosine45-Maleimide
|
Drug Delivery
|
|
N-Tetamine-pSar45-Maleimide (N-Tetamine-polySarcosine45-Maleimide) is a pSar-lipid derivative. As a hydrophilic alternative to PEG, N-Tetamine-pSar45-Maleimide can be used in drug delivery research .
|
-
- HY-157919
-
|
N-6-(Biotinylamino)hexanoyl-N'-[2-(N-maleimido)ethyl]piperazine, hydrochloride
|
Biochemical Assay Reagents
|
|
Biotin-PEAC5-maleimide hydrochloride is a biochemical assay reagent, and can be used in biotin-PEAC5-maleimide (BPM)-labeling assay to assess modification of protein thiols by electrophiles .
|
-
- HY-W739513
-
-
- HY-168938
-
|
|
Drug Delivery
|
|
Poly(ethylene glycol) methyl ether maleimide (Mn 2000) is a polyethylene glycol containing Maleimide (HY-W007324). Due to the Maleimide functional group, Poly(ethylene glycol) methyl ether maleimide (Mn 2000) can be used to conjugate biomolecules containing thiol groups.
|
-
- HY-W879049
-
|
DBCO-NHCO-PEG3-maleimide
|
Drug Delivery
|
|
DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-W879036
-
|
|
Drug Delivery
|
|
DBCO-PEG8-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG8-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-W441009E
-
|
|
Drug Delivery
|
|
DSPE-PEG-Maleimide (MW 20000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 20000) ammonium can be used in drug delivery research .
|
-
- HY-W441009A
-
|
|
Drug Delivery
|
|
DSPE-PEG-Maleimide (MW 3400) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 3400) ammonium can be used in drug delivery research .
|
-
- HY-W441009C
-
|
|
Drug Delivery
|
|
DSPE-PEG-Maleimide (MW 4000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 4000) ammonium can be used in drug delivery research .
|
-
- HY-W441009B
-
|
|
Drug Delivery
|
|
DSPE-PEG-Maleimide (MW 1000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 1000) ammonium can be used in drug delivery research .
|
-
- HY-W441009H
-
|
|
Drug Delivery
|
|
DSPE-PEG-Maleimide (MW 40000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 40000) ammonium can be used in drug delivery research .
|
-
- HY-W441009D
-
|
|
Drug Delivery
|
|
DSPE-PEG-Maleimide (MW 10000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 10000) ammonium can be used in drug delivery research .
|
-
- HY-W1048661E
-
|
|
Drug Delivery
|
|
Biotin-PEG-maleimide (MW 2000) is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG-maleimide (MW 2000) anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661H
-
|
|
Drug Delivery
|
|
Biotin-PEG-maleimide (MW 3400) is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG-maleimide (MW 3400) anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661A
-
|
|
Drug Delivery
|
|
Biotin-PEG-maleimide (MW 5000) is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG-maleimide (MW 5000) anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661
-
|
|
Drug Delivery
|
|
Biotin-PEG-maleimide (MW 1000) is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG-maleimide (MW 1000) anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-171561G
-
|
|
Biochemical Assay Reagents
|
|
DOTAM-Maleimide triTFA (GMP) is DOTAM-Maleimide triTFA (HY-171561) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAM-Maleimide triTFA is a bifunctional chelator .
|
-
- HY-W017588
-
|
|
Biochemical Assay Reagents
|
|
N-(2-Hydroxyethyl)maleimide is a cross-linker. N-(2-Hydroxyethyl)maleimide is used for chemical synthesis .
|
-
- HY-174927E
-
|
DBCO-PEG-Mal (MW 3400)
|
Drug Delivery
|
|
DBCO-PEG-Maleimide (MW 3400) (DBCO-PEG-Mal (MW 3400)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 3400) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927B
-
|
DBCO-PEG-Mal (MW 600)
|
Drug Delivery
|
|
DBCO-PEG-Maleimide (MW 600) (DBCO-PEG-Mal (MW 600)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 600) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927A
-
|
DBCO-PEG-Mal (MW 400)
|
Drug Delivery
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DBCO-PEG-Maleimide (MW 400) (DBCO-PEG-Mal (MW 400)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 400) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
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-
- HY-174927
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DBCO-PEG-Mal (MW 5000)
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Drug Delivery
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DBCO-PEG-Maleimide (MW 5000) (DBCO-PEG-Mal (MW 5000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 5000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
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- HY-174927D
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DBCO-PEG-Mal (MW 2000)
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Drug Delivery
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DBCO-PEG-Maleimide (MW 2000) (DBCO-PEG-Mal (MW 2000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 2000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
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- HY-174927C
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DBCO-PEG-Mal (MW 1000)
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Drug Delivery
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DBCO-PEG-Maleimide (MW 1000) (DBCO-PEG-Mal (MW 1000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 1000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
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- HY-174921
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Drug Delivery
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Maleimide-PEG-COOH (MW 1000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
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- HY-174921B
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Drug Delivery
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Maleimide-PEG-COOH (MW 3400) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
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- HY-174921C
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Drug Delivery
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Maleimide-PEG-COOH (MW 5000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
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- HY-174921A
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Drug Delivery
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Maleimide-PEG-COOH (MW 2000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
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- HY-174885C
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Drug Delivery
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Acrylate-PEG-Maleimide (MW 5000) is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
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- HY-174885
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Drug Delivery
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|
Acrylate-PEG-Maleimide (MW 1000) is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
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- HY-174885B
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Drug Delivery
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|
Acrylate-PEG-Maleimide (MW 3400) is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
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- HY-174885A
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Drug Delivery
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Acrylate-PEG-Maleimide (MW 2000) is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
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- HY-133540G
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Maleimido-mono-amide-DOTA (GMP)
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Biochemical Assay Reagents
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Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W087027A
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Chelators
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Maleimide-NOTA (TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. Maleimide-NOTA (TFA) can be used for conjugation of peptides and radionuclides.
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- HY-W808757
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Biochemical Assay Reagents
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|
Biotin-maleimide is a biotinylated biochemical assay reagent, which can be used as a thiol-specific probe. Biotin-maleimide can also be used to prepare the biotin-conjugated polychelating agent .
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- HY-174941
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Drug Delivery
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Mal-PEG18-acid is a PEG derivative modified with maleimide groups. Maleimide is a functional group that can undergo Michael addition reaction with sulfhydryl (–SH) groups and can be used for bioconjugation.
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- HY-W440718C
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Drug Delivery
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Cholesterol-PEG-Mal (MW 10000) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-W440718A
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Drug Delivery
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Cholesterol-PEG-Mal (MW 400) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-W440718B
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Drug Delivery
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Cholesterol-PEG-Mal (MW 600) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-174953D
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Drug Delivery
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TPP-PEG-Mal (MW 10000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-174953A
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Drug Delivery
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TPP-PEG-Mal (MW 2000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-174953
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Drug Delivery
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TPP-PEG-Mal (MW 1000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-174953B
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Drug Delivery
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TPP-PEG-Mal (MW 3400) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-174953C
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Drug Delivery
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TPP-PEG-Mal (MW 5000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-W190746
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Drug Delivery
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Mal-PEG1-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
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- HY-W190755
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Drug Delivery
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Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
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- HY-W1048555B
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Drug Delivery
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Mal-PEG-SCM (MW 3400) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 3400) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555A
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Drug Delivery
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Mal-PEG-SCM (MW 2000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 2000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555D
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Drug Delivery
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Mal-PEG-SCM (MW 10000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 10000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555H
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Drug Delivery
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Mal-PEG-SCM (MW 40000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 40000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555C
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Drug Delivery
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Mal-PEG-SCM (MW 5000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 5000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555E
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Drug Delivery
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Mal-PEG-SCM (MW 20000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 20000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555
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Drug Delivery
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Mal-PEG-SCM (MW 1000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 1000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W068119A
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2-Maleimidoethylamine hydrochloride
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Biochemical Assay Reagents
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N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a cross-linker. N-(2-Aminoethyl)maleimide hydrochloride can be used to prepare MMP-2 sensitive nanosystem, and for cancer research .
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- HY-W011692
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- HY-166990
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MeO-PEG-Mal (MW 5000)
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Biochemical Assay Reagents
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Methoxypolyethylene glycol maleimide (MeO-PEG-Mal) is a biochemical assay reagent.
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- HY-W1048553C
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Drug Delivery
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Mal-PEG-NH2 TFA (MW 5000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553H
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Drug Delivery
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Mal-PEG-NH2 TFA (MW 40000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553A
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Drug Delivery
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Mal-PEG-NH2 TFA (MW 2000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553B
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Drug Delivery
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Mal-PEG-NH2 TFA (MW 3400) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553E
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Drug Delivery
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Mal-PEG-NH2 TFA (MW 20000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553
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Drug Delivery
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Mal-PEG-NH2 TFA (MW 1000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553D
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Drug Delivery
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Mal-PEG-NH2 TFA (MW 10000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-174961C
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Fmoc-NH-PEG-Mal (MW 5000)
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Drug Delivery
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Fmoc-PEG-Maleimide (MW 5000) (Fmoc-NH-PEG-Mal (MW 5000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-174961B
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Fmoc-NH-PEG-Mal (MW 3400)
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Drug Delivery
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Fmoc-PEG-Maleimide (MW 3400) (Fmoc-NH-PEG-Mal (MW 3400)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-174961
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Fmoc-NH-PEG-Mal (MW 1000)
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Drug Delivery
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Fmoc-PEG-Maleimide (MW 1000) (Fmoc-NH-PEG-Mal (MW 1000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-174961A
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Fmoc-NH-PEG-Mal (MW 2000)
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Drug Delivery
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Fmoc-PEG-Maleimide (MW 2000) (Fmoc-NH-PEG-Mal (MW 2000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-167036C
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Drug Delivery
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DMG-PEG-Mal (MW 5000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 5000) can be used for drug delivery .
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- HY-167036A
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Drug Delivery
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DMG-PEG-Mal (MW 1000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 1000) can be used for drug delivery .
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- HY-167036D
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Drug Delivery
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DMG-PEG-Mal (MW 10000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 10000) can be used for drug delivery .
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- HY-157920
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N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine
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Biochemical Assay Reagents
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Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
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- HY-167036B
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Drug Delivery
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DMG-PEG-Mal (MW 3400) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 3400) can be used for drug delivery .
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- HY-166648
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Drug Delivery
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DSPE-PEG-Maleimide (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-PEG-Maleimide (MW 2000)can be used in drug delivery research .
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- HY-166990B
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MeO-PEG-Mal (MW 2000)
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Biochemical Assay Reagents
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Methoxypolyethylene glycol maleimide (MW 2000) (MeO-PEG-Mal (MW 2000)) is a biochemical reagent .
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- HY-166990C
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MeO-PEG-Mal (MW 750)
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Biochemical Assay Reagents
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Methoxypolyethylene glycol maleimide (MW 750) (MeO-PEG-Mal (MW 750)) is a biochemical reagent .
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- HY-166990A
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MeO-PEG-Mal (MW 10000)
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Biochemical Assay Reagents
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Methoxypolyethylene glycol maleimide (MW 10000) (MeO-PEG-Mal (MW 10000)) is a biochemical reagent .
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- HY-W591618D
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4-Arm-PEG-Mal (MW 3400)
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Drug Delivery
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4-Arm-PEG-Maleimide (MW 3400) (4-Arm-PEG-Mal (MW 3400)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-W591618B
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4-Arm-PEG-Mal (MW 600)
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Drug Delivery
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4-Arm-PEG-Maleimide (MW 600) (4-Arm-PEG-Mal (MW 600)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-W591465
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4-Arm-PEG-Mal (MW 2000)
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Drug Delivery
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4-Arm-PEG-Maleimide (MW 2000) (4-Arm-PEG-Mal (MW 2000)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-W591618A
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4-Arm-PEG-Mal (MW 400)
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Drug Delivery
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4-Arm-PEG-Maleimide (MW 400) (4-Arm-PEG-Mal (MW 400)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-W591618C
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4-Arm-PEG-Mal (MW 1000)
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Drug Delivery
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4-Arm-PEG-Maleimide (MW 1000) (4-Arm-PEG-Mal (MW 1000)) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-163790
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- HY-163789
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Biochemical Assay Reagents
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Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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- HY-W011433
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Biochemical Assay Reagents
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N-(1-Pyrenyl)maleimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-155902D
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Maleimide-PEG-Hydroxy (MW 10000)
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Drug Delivery
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Mal-PEG-OH (MW 10000) (Maleimide-PEG-Hydroxy (MW 10000)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 10000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
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- HY-155902E
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Maleimide-PEG-Hydroxy (MW 20000)
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Drug Delivery
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Mal-PEG-OH (MW 20000) (Maleimide-PEG-Hydroxy (MW 20000)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 20000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
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- HY-155902H
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Maleimide-PEG-Hydroxy (MW 40000)
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Drug Delivery
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Mal-PEG-OH (MW 40000) (Maleimide-PEG-Hydroxy (MW 40000)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 40000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
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- HY-155902C
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Maleimide-PEG-Hydroxy (MW 3400)
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Drug Delivery
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Mal-PEG-OH (MW 3400) (Maleimide-PEG-Hydroxy (MW 3400)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 3400) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
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- HY-D0975
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Biochemical Assay Reagents
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Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
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- HY-W1049129D
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Drug Delivery
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Mal-PEG-mal (MW 40000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 40000) can be used for drug delivery .
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- HY-W1048552
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Drug Delivery
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Mal-PEG-mal (MW 1000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 1000) can be used for drug delivery .
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- HY-W1049129C
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Drug Delivery
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Mal-PEG-mal (MW 20000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 20000) can be used for drug delivery .
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- HY-174914
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Drug Delivery
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Biotin-PEG4-mal is a PEG derivative composed of Biotin, 4 PEG units and Maleimide. Biotin can form a stable non-covalent bond with streptavidin.
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- HY-W1049129B
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Drug Delivery
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Mal-PEG-mal (MW 10000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 10000) can be used for drug delivery .
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- HY-W020780C
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mPEG-Maleimide (MW 3400)
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Drug Delivery
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|
mPEG-Mal (MW 3400) is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
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- HY-W020780A
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mPEG-Maleimide (MW 350)
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Drug Delivery
|
|
mPEG-Mal (MW 350) is a PEG derivative used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
- HY-W020780B
-
|
mPEG-Maleimide (MW 750)
|
Drug Delivery
|
|
mPEG-Mal (MW 750) is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
- HY-W440722
-
|
|
Drug Delivery
|
|
Cholesterol-PEG-Thiol (MW 1000) is a PEGylated lipid that forms micelles in water and can be used to prepare liposomes or nanoparticles as drug delivery systems. The thiol moiety reacts with maleimide to form a stable thioether bond .
|
- HY-W1048605
-
|
|
Drug Delivery
|
|
8-Arm PEG-Mal (MW 5000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 5000) can be used for drug delivery .
|
- HY-W1048605C
-
|
|
Drug Delivery
|
|
8-Arm PEG-Mal (MW 40000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 40000) can be used for drug delivery .
|
- HY-W1048510B
-
|
|
Drug Delivery
|
|
2-Arm PEG-Mal (MW 20000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 20000) can be used for drug delivery .
|
- HY-W1048510A
-
|
|
Drug Delivery
|
|
2-Arm PEG-Mal (MW 10000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 10000) can be used for drug delivery .
|
- HY-W1048510C
-
|
|
Drug Delivery
|
|
2-Arm PEG-Mal (MW 40000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 40000) can be used for drug delivery .
|
- HY-W1048510D
-
|
|
Drug Delivery
|
|
2-Arm PEG-Mal (MW 5000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 5000) can be used for drug delivery .
|
- HY-W1048605B
-
|
|
Drug Delivery
|
|
8-Arm PEG-Mal (MW 10000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 10000) can be used for drug delivery .
|
- HY-W1048605A
-
|
|
Drug Delivery
|
|
8-Arm PEG-Mal (MW 20000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 20000) can be used for drug delivery .
|
- HY-155901
-
|
Maleimide-NH-PEG-amine TFA (MW 2000)
|
Drug Delivery
|
|
Mal-NH-PEG-NH2 (TFA) (MW 2000) is a PEG derivative that may be used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
- HY-W440897
-
|
|
Drug Delivery
|
|
DSPE-PEG-SH, MW 3400 is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA. Reagent grade, for research use only.
|
- HY-W441007
-
|
|
Drug Delivery
|
|
DSPE-MAL is a phospholipid compound with a maleimide reactive group. DSPE-MAL contains two saturated fatty acids and can self-assemble in water to form a lipid bilayer. DSPE-MAL can be used to prepare liposomes as nanocarriers for active molecules .
|
- HY-W440896
-
|
|
Drug Delivery
|
|
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
|
- HY-174809A
-
|
|
Drug Delivery
|
|
6-Arm-PEG-Mal (MW 600) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809E
-
|
|
Drug Delivery
|
|
6-Arm-PEG-Mal (MW 5000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809H
-
|
|
Drug Delivery
|
|
6-Arm-PEG-Mal (MW 10000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809
-
|
|
Drug Delivery
|
|
6-Arm-PEG-Mal (MW 400) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809C
-
|
|
Drug Delivery
|
|
6-Arm-PEG-Mal (MW 2000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809D
-
|
|
Drug Delivery
|
|
6-Arm-PEG-Mal (MW 3400) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809B
-
|
|
Drug Delivery
|
|
6-Arm-PEG-Mal (MW 1000) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-W588728
-
|
|
Drug Delivery
|
|
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
- HY-W588736
-
|
|
Drug Delivery
|
|
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
- HY-W1048849A
-
|
4-Arm PEG-thiol (MW 5000)
|
Drug Delivery
|
|
4-Arm PEG-SH (MW 5000) (4-Arm PEG-thiol (MW 5000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
- HY-W1048849D
-
|
4-Arm PEG-thiol (MW 40000)
|
Drug Delivery
|
|
4-Arm PEG-SH (MW 40000) (4-Arm PEG-thiol (MW 40000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
- HY-W1048849C
-
|
4-Arm PEG-thiol (MW 20000)
|
Drug Delivery
|
|
4-Arm PEG-SH (MW 20000) (4-Arm PEG-thiol (MW 20000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
- HY-W1048849B
-
|
4-Arm PEG-thiol (MW 10000)
|
Drug Delivery
|
|
4-Arm PEG-SH (MW 10000) (4-Arm PEG-thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
- HY-W1048545I
-
|
|
Drug Delivery
|
|
H2N-PEG-SH (MW 3400) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 3400) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545A
-
|
|
Drug Delivery
|
|
H2N-PEG-SH (MW 2000) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 2000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545C
-
|
|
Drug Delivery
|
|
H2N-PEG-SH (MW 5000) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 5000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545H
-
|
Amine-PEG-Thiol (MW 1000)
|
Drug Delivery
|
|
H2N-PEG-SH (MW 1000) (Amine-PEG-Thiol (MW 1000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 1000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545E
-
|
Amine-PEG-Thiol (MW 20000)
|
Drug Delivery
|
|
H2N-PEG-SH (MW 20000) (Amine-PEG-Thiol (MW 20000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 20000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545D
-
|
Amine-PEG-Thiol (MW 10000)
|
Drug Delivery
|
|
H2N-PEG-SH (MW 10000) (Amine-PEG-Thiol (MW 10000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 10000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-13631EG
-
|
MC-GGFG-DXD (GMP)
|
Biochemical Assay Reagents
|
|
Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
|
- HY-W1048545J
-
|
Amine-PEG-Thiol (MW 40000)
|
Drug Delivery
|
|
H2N-PEG-SH (MW 40000) (Amine-PEG-Thiol (MW 40000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 40000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4113
-
|
|
Peptides
|
Neurological Disease
|
|
TAT-NSF700 Fusion Peptide is a potent N-ethyl-maleimide-sensitive factor (NSF) inhibitor. TAT-NSF700 Fusion Peptide can readily permeate the cell membrane and interact with the intracellular organelle directly .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-A0023AS2
-
|
|
|
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-13631ES4
-
|
|
|
Deruxtecan-d5 is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
-
- HY-13631ES
-
|
|
|
Deruxtecan-d4 is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
-
- HY-13631ES3
-
|
|
|
Deruxtecan-d2 is the deuterium labeled Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
-
- HY-13631ES2
-
|
|
|
Deruxtecan-d4-1 is the deuterium labeled Adenosine Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W879048
-
|
|
|
DBCO
|
|
DBCO-PEG24-Maleimide contains a maleimide and a DBCO group. DBCO-PEG24-Maleimide can be used for thiol-containing biomolecule conjugations. DBCO-PEG24-Maleimide can be used in click chemistry with azide-bearing biomolecules .
|
-
- HY-156307
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156312
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156308
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156391A
-
|
|
|
TCO
|
|
TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-156391
-
|
|
|
TCO
|
|
TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-156392
-
|
|
|
TCO
|
|
TCO4-PEG7-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG7-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-W872575A
-
|
|
|
TCO
|
|
TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-W872575
-
|
|
|
TCO
|
|
TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-156322
-
|
|
|
BCN
|
|
BCN-exo-PEG3-maleimide is an ADC Linker containing 3 PEG units. BCN-exo-PEG3-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which enables the further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-134734
-
|
|
|
BCN
|
|
BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156320
-
|
|
|
BCN
|
|
BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-151696
-
|
|
|
TCO
|
|
TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) .
|
-
- HY-156311
-
|
|
|
ADC Synthesis
BCN
|
|
BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-157008
-
|
|
|
ADC Synthesis
TCO
|
|
(S)-TCO-PEG2-Maleimide is an ADC linker containing 2 PEG units. (S)-TCO-PEG2-Maleimide can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-133399
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133475
-
|
|
|
TCO
PROTAC Synthesis
|
|
TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133372
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-NHCO-PEG2-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140307
-
|
|
|
DBCO
PROTAC Synthesis
|
|
Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133374
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-NHCO-PEG12-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG12-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133373
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-NHCO-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-120770
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141278
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133468
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG6-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140307A
-
|
|
|
DBCO
|
|
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide (TEA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133477
-
|
|
|
PROTAC Synthesis
TCO
|
|
(S)-TCO-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . (S)-TCO-PEG3-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-141184
-
|
|
|
TCO
|
|
TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156488
-
|
|
|
TCO
|
|
TCO-PEG7-Maleimide contains TCO groups, and can undergo specific "click" reactions with tetrazine groups.
|
-
- HY-156317
-
|
|
|
BCN
|
|
BCN-endo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-116270
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136104
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-140740
-
|
|
|
Pegylated Lipids
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DSPE-PEG-Maleimide, MW 5000 has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-maleimide extends blood circulation time and higher stability for encapsulated agents .
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- HY-144004
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DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
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Pegylated Lipids
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DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
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- HY-144004A
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DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
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Pegylated Lipids
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DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
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- HY-140739
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Pegylated Lipids
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DSPE-PEG2000-Maleimide is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
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- HY-W441009A
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Pegylated Lipids
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DSPE-PEG-Maleimide (MW 3400) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 3400) ammonium can be used in drug delivery research .
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- HY-W441004
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Phospholipids
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DSPE-Thiol is a phophalipid capped with thiol group. The thiol capped head can selectively react with maleimide. DSPE-Thiol can also be used for the preparation of phospholipid dimers .
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- HY-W800787
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Phospholipids
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18:1 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a maleimide group.
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- HY-W800786
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N-MCC-PE
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Phospholipids
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16:0 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a maleimide group.
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- HY-W800789
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Phospholipids
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16:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.
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- HY-W800788
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Phospholipids
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18:1 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a phenyl maleimide group.
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- HY-W020780C
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mPEG-Maleimide (MW 3400)
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Polymers
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mPEG-Mal (MW 3400) is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
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- HY-W020780A
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mPEG-Maleimide (MW 350)
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Polymers
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mPEG-Mal (MW 350) is a PEG derivative used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
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- HY-W020780B
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mPEG-Maleimide (MW 750)
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Polymers
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mPEG-Mal (MW 750) is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
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- HY-W590555
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Pegylated Lipids
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Thiol-PEG-DMG, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
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- HY-W440719
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Pegylated Lipids
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Cholesterol-PEG-MAL (MW 2000) is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
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- HY-W440724
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Pegylated Lipids
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Cholesterol-PEG-Thiol (MW 3400) is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
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- HY-155901
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Maleimide-NH-PEG-amine TFA (MW 2000)
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Polymers
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Mal-NH-PEG-NH2 (TFA) (MW 2000) is a PEG derivative that may be used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
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- HY-W441007
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Phospholipids
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DSPE-MAL is a phospholipid compound with a maleimide reactive group. DSPE-MAL contains two saturated fatty acids and can self-assemble in water to form a lipid bilayer. DSPE-MAL can be used to prepare liposomes as nanocarriers for active molecules .
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- HY-W440896
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Pegylated Lipids
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DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
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- HY-W800805
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Phospholipids
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DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
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