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α,β-Methylene-ATP trisodium is an agonist of P2X1 and P2X3 receptors and can cross the blood-brain barrier. α,β-Methylene-ATP trisodium can trigger a reflex pressor response by activating P2X receptors in peripheral muscles and the central locus coeruleus (LC); this effect can be blocked by the P2X antagonist PPADS (HY-108960). α,β-Methylene-ATP trisodium also activates noradrenergic neurons in the central locus coeruleus, mediating antinociceptive effects; this effect can be attenuated by the locus coeruleus damaging agent DSP-4 (HY-103210/HY-121602). α,β-Methylene-ATP trisodium can be used to study the pathological mechanisms of neuropathic pain, cardiovascular reflex regulation, and antinociceptive effects of the central nervous system .
MS37452 is a potent inhibitor of CBX7 chromodomain binding to H3K27me3, with a Kd of 27.7 μM. MS37452 can derepress transcription of polycomb repressive complex target gene p16/CDKN2A by displacing CBX7 binding to the INK4A/ARFlocus in prostate cancer cells .
α,β-Methylene-ATP is an agonist of P2X1 and P2X3 receptors and can cross the blood-brain barrier. α,β-Methylene-ATP can trigger a reflex pressor response by activating P2X receptors in peripheral muscles and the central locus coeruleus (LC); this effect can be blocked by the P2X antagonist PPADS (HY-108960). α,β-Methylene-ATP also activates noradrenergic neurons in the central locus coeruleus, mediating antinociceptive effects; this effect can be attenuated by the locus coeruleus damaging agent DSP-4 (HY-103210/HY-121602). α,β-Methylene-ATP can be used to study the pathological mechanisms of neuropathic pain, cardiovascular reflex regulation, and antinociceptive effects of the central nervous system .
α,β-Methylene-ATP dilithium is an agonist of P2X1 and P2X3 receptors and can cross the blood-brain barrier. α,β-Methylene-ATP dilithium can trigger a reflex pressor response by activating P2X receptors in peripheral muscles and the central locus coeruleus (LC); this effect can be blocked by the P2X antagonist PPADS (HY-108960). α,β-Methylene-ATP dilithium also activates noradrenergic neurons in the central locus coeruleus, mediating antinociceptive effects; this effect can be attenuated by the locus coeruleus damaging agent DSP-4 (HY-103210/HY-121602). α,β-Methylene-ATP dilithium can be used to study the pathological mechanisms of neuropathic pain, cardiovascular reflex regulation, and antinociceptive effects of the central nervous system .
DSP 4 Free base is a selective neurotoxin that targets noradrenergic neurons in the locus coeruleus noradrenergic system. DSP 4 Free base possesses the unique ability to cross the blood–brain barrier. DSP 4 Free base cyclizes to form a reactive aziridinium derivative that accumulates in noradrenergic neurons.
SP1 is an α-peptide encoded by the mating pheromone MFα1 gene in Candida albicans, which can induce cell growth arrest at the mating type locus MTLa in Candida albicans. SP1 can be used in the study of the prevention and treatment of Candida albicans infection .
JNJ10191584 (VUF6002) maleate (compound 40) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 maleate shows 540-fold selectivity to H4 receptor over the H3 receptor with a Ki value of 14.1 μM. JNJ10191584 maleate inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively .
JNJ10191584 (VUF6002) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 shows 540-fold selectivity to H4 receptor over H3 receptor with a Ki value of 14.1 μM. JNJ10191584 inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively .
DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons .
SP1 is an α-peptide encoded by the mating pheromone MFα1 gene in Candida albicans, which can induce cell growth arrest at the mating type locus MTLa in Candida albicans. SP1 can be used in the study of the prevention and treatment of Candida albicans infection .
NOTCH1 Protein acts as a receptor for membrane-bound ligands (JAG1, JAG2, and DLL1), determining cell fate.Upon activation, NICD forms a transcriptional activator complex, influencing differentiation, proliferation, and apoptosis.NOTCH1 negatively regulates angiogenesis, endothelial cell behavior, and impacts various developmental processes.It interacts with multiple partners, illustrating its involvement in signaling networks.NOTCH1 Protein, Mouse (sf9, His) is the recombinant mouse-derived NOTCH1 protein, expressed by Sf9 insect cells , with C-His labeled tag.
NOTCH1 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH1 Protein, Human (HEK293, Fc) is the recombinant human-derived NOTCH1 protein, expressed by HEK293 , with C-hFc labeled tag.
NOTCH1 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH1 Protein, Mouse (CHO, mFc) is the recombinant mouse-derived NOTCH1 protein, expressed by CHO , with C-mFc labeled tag.
Notch 3 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and plays a crucial regulatory role in cell fate determination. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes within the enhancer of the cleavage site. Notch3 Protein, Human (HEK293, Fc) is the recombinant human-derived Notch3 protein, expressed by HEK293 , with C-hFc labeled tag.
CTACK/CCL27 Protein, Human is a CC chemokine that binds to the chemokine receptor CCR10, attracts skin-associated memory T lymphocytes, mediates lymphocyte homing to skin sites, and plays a key role in skin inflammation. CTACK/CCL27 Protein, Human a recombinant human CTACK/CCL27 (F25-G112) protein expressed by E. coli.
TYR/Tyrosinase Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived TYR/Tyrosinase protein, expressed by E. coli Cell-free, with N-10*His labeled tag., has molecular weight of 61.3 kDa.
NOTCH4 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH4 Protein, Human (sf9, His) is the recombinant human-derived NOTCH4 protein, expressed by Sf9 insect cells , with C-His labeled tag.
NOTCH1 Protein acts as a receptor for membrane-bound ligands (JAG1, JAG2, and DLL1), determining cell fate.Upon activation, NICD forms a transcriptional activator complex, influencing differentiation, proliferation, and apoptosis.NOTCH1 negatively regulates angiogenesis, endothelial cell behavior, and impacts various developmental processes.It interacts with multiple partners, illustrating its involvement in signaling networks.NOTCH1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived NOTCH1 protein, expressed by HEK293 , with C-6*His labeled tag.
CTACK/CCL27 protein attracts skin-associated memory T-lymphocytes, mediating lymphocyte homing to the skin. It may also participate in embryonic cell migration. Nuclear forms of CCL27 induce cytoskeletal relaxation. The protein binds to CCR10, exists in monomeric, dimeric, and tetrameric forms, and heparin promotes oligomerization. Additionally, CCL27 interacts with TNFAIP6 through its Link domain. CTACK/CCL27 Protein, Mouse is the recombinant mouse-derived CTACK/CCL27 protein, expressed by E. coli , with tag free.
LY6G6D Protein is a leukocyte antigen-6 (LY6) gene cluster located in the Major Histocompatibility complex (MHC) Class III region of chromosome 6. LY6G6D Protein is involved in the JAK-STAT5 and RAS-MEK-ERK signaling pathways, and is a selective expression of colorectal cancer antigen. Therapeutic T-cell responses can be targeted through T-cell adaptors. LY6G6D Protein, Human (P.pastoris, His) is the recombinant human-derived LY6G6D protein, expressed by P. pastoris , with N-6*His labeled tag.
CTACK/CCL27 protein selectively attracts skin-associated memory T-lymphocytes, mediating their homing to cutaneous sites through CCR10 binding. Crucial for skin immunity regulation, CCL27 exists as a monomer, dimer, and tetramer, with heparin promoting its oligomerization. Interaction with TNFAIP6, particularly through its Link domain, implies regulatory roles in skin immune responses and inflammation within the skin microenvironment. CTACK/CCL27 Protein, Human (His) is the recombinant human-derived CTACK/CCL27 protein, expressed by E. coli , with N-His labeled tag.
LY6G6D Protein is a leukocyte antigen-6 (LY6) gene cluster located in the Major Histocompatibility complex (MHC) Class III region of chromosome 6. LY6G6D Protein is involved in the JAK-STAT5 and RAS-MEK-ERK signaling pathways, and is a selective expression of colorectal cancer antigen. Therapeutic T-cell responses can be targeted through T-cell adaptors. LY6G6D Protein, Human ((HEK293, Fc) is the recombinant human-derived LY6G6D protein, expressed by heterologous system, with N-hFc labeled tag.
LY6G6D Protein is a leukocyte antigen-6 (LY6) gene cluster located in the Major Histocompatibility complex (MHC) Class III region of chromosome 6. LY6G6D Protein is involved in the JAK-STAT5 and RAS-MEK-ERK signaling pathways, and is a selective expression of colorectal cancer antigen. Therapeutic T-cell responses can be targeted through T-cell adaptors. LY6G6D Protein, Human (HEK293, His) is the recombinant human-derived LY6G6D protein, expressed by HEK293, with N-His labeled tag.
DCT (Dopachrome tautomerase) is pivotal in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a critical step in melanin synthesis. DCT's enzymatic activity is integral to the complex processes governing melanin production, emphasizing its role in skin pigmentation and the regulation of melanin-related functions. DCT Protein, Mouse (His-SUMO) is the recombinant mouse-derived DCT protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag.
B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA class I histocompatibility antigen alpha chain G; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC G; T-cell A locus; TCA
HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. HLA-G Protein, Human (HEK293, His) is the recombinant human-derived HLA-G protein, expressed by HEK293 , with N-His labeled tag.
CTACK/CCL27 protein plays a crucial role in chemokine activity and cell chemotaxis. It regulates T cell chemotaxis and actin cytoskeletal reorganization, suggesting its involvement in immune responses and cell motility. CTACK/CCL27 Protein, Mouse is the recombinant mouse-derived CTACK/CCL27 protein, expressed by E. coli , with tag free.
B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA class I histocompatibility antigen alpha chain G; HLA class I histocompatibility antigen; alpha chain G; HLA class I molecule; HLA G; HLA G antigen; HLA G histocompatibility antigen class I G; HLA G3; HLA-G; HLA-G histocompatibility antigen; class I; HLA60; HLAG; HLAG_HUMAN; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC G; T-cell A locus; TCA
HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. HLA-G Protein, Human (His-SUMO) is the recombinant human-derived HLA-G protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV
WB, IHC-P
Human
Melanocyte Protein PMEL Antibody (YA2829) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2829), targeting Melanocyte Protein PMEL, with a predicted molecular weight of 70 kDa (observed band size: 100 kDa). Melanocyte Protein PMEL Antibody (YA2829) can be used for WB, IHC-P experiment in human background.
NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1
WB, IHC-P, ICC/IF, FC
Human, Mouse, Rat
Notch1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 273 kDa, targeting to Notch1. It can be used for WB,IHC-P,ICC/IF,FC assays with tag free, in the background of Human, Mouse, Rat.
DKFZp686O09161 antibody; MCPH7 antibody; OTTHUMP00000009566 antibody; SCL interrupting locus protein antibody; SCL-interrupting locus protein antibody; SCL/TAL1 interrupting locus antibody; SIL antibody; STIL antibody; STIL_HUMAN antibody; TAL 1 interrupting locus protein antibody; DKFZp686O09161 antibody; MCPH7 antibody; OTTHUMP00000009566 antibody; SCL interrupting locus protein antibody; SCL-interrupting locus protein antibody; SCL/TAL1 interrupting locus antibody; SIL antibody; STIL antibody; STIL_HUMAN antibody; TAL 1 interrupting locus protein antibody; TAL-1-interrupting locus protein antibody
ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 1
WB, ICC/IF
Human
ATP Synthase C Antibody (YA1633) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1633), targeting ATP Synthase C, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). ATP Synthase C Antibody (YA1633) can be used for WB, ICC/IF experiment in human background.
ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 1
WB, IHC-P, IP
Human, Rat
ATP5G Antibody (YA2205) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2205), targeting ATP5G, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). ATP5G Antibody (YA2205) can be used for WB, IHC-P, IP experiment in human, rat background.
Surfeit Locus Protein 4 Antibody (YA2465) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2465), targeting Surfeit Locus Protein 4, with a predicted molecular weight of 30 kDa (observed band size: 30 kDa). Surfeit Locus Protein 4 Antibody (YA2465) can be used for WB, ICC/IF experiment in human, mouse, rat background.
TRMT2A Antibody (YA1663) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1663), targeting TRMT2A, with a predicted molecular weight of 69 kDa (observed band size: 69 kDa). TRMT2A Antibody (YA1663) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human background.
NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4
WB
Human
Notch4 Antibody (YA2557) is a non-conjugated IgG antibody, targeting Notch4, with a predicted molecular weight of 210 kDa (observed band size: 36 kDa). Notch4 Antibody (YA2557) can be used for WB experiment in human background.
NOTCH2; Neurogenic locus notch homolog protein 2; Notch 2; hN2
WB, IHC-P, ICC/IF, IP, ELISA
Human, Mouse, Rat
Notch 2 Antibody (YA6134) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Notch 2. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.
Ly6g Antibody (YA6106) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Ly6g. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of mouse.
NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1
WB, IHC-P, ICC/IF, IP, ELISA
Human, Mouse, Rat
Notch1 Antibody (YA6283) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Notch1. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.
alpha pal; alpha palindromic binding protein; Alpha palindromic-binding protein; Alpha-pal; locus control region factor 1; NFE2 related factor 1; NRF-1; Nrf1; NRF1_HUMAN; Nuclear respiratory factor 1; transcription factor 11.
WB, IHC-F, IHC-P, ICC/IF, IP
Human, Mouse, Rat
Nrf1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 54 kDa, targeting to Nrf1. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.
ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9; Tether containing UBX domain for GLUT4; Alveolar soft part sarcoma chromosomal region candidate gene 1 protein; Alveolar soft part sarcoma locus; Renal papillary cell carcinoma protein 17; UBX domain
WB, ELISA
Mouse
TUG Antibody (YA5093) is a mouse-derived and non-conjugated monoclonal antibody, targeting to TUG. It can be applicated for WB, ELISA assays, in the background of mouse.
alpha pal; alpha palindromic binding protein; Alpha palindromic-binding protein; Alpha-pal; locus control region factor 1; NFE2 related factor 1; NRF-1; Nrf1; NRF1_HUMAN; Nuclear respiratory factor 1; transcription factor 11.
WB
Human
NRF-1 Antibody (YA5263) is a mouse-derived and non-conjugated monoclonal antibody, targeting to NRF-1. It can be applicated for WB assays, in the background of human.
Glycophorin A Antibody (YA5608) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Glycophorin A. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human.
HMB45 Antibody (YA5625) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HMB45. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human, mouse.
HMB45 Antibody (YA5749) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HMB45. It can be applicated for IHC-P, ELISA assays, in the background of human, mouse.
