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iridoid glycoside

" in MedChemExpress (MCE) Product Catalog:

42

Inhibitors & Agonists

42

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N8046
    Gardoside

    		Others Others
    Gardoside is an iridoid glycoside that can be found in the roots of L. alba .
    Gardoside
  • HY-N0820
    Catalpol
    Maximum Cited Publications
    10 Publications Verification

    Catalpinoside

    		 HBV Infection Neurological Disease Inflammation/Immunology Cancer
    Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .
    Catalpol
  • HY-N5086
    Picroside IV

    		HBV Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .
    Picroside IV
  • HY-N0914
    Ajugol
    2 Publications Verification

    		 Parasite Autophagy Interleukin Related Reactive Oxygen Species (ROS) mTOR Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Ajugol is an orally active iridoid glycoside found in the traditional Chinese medicine Leonurus japonicus. Ajugol is an autophagy activator. Ajugol activates TFEB-mediated autophagy and lysosomal biogenesis. Ajugol also has anti-inflammatory effects. Ajugol has great potential in the research of asthma, non-alcoholic fatty liver disease (NAFLD), and osteoarthritis .
    Ajugol
  • HY-N2712
    6''-O-trans-Feruloylcatalpol

    		Others Others
    6''-O-trans-Feruloylcatalpol is a natural iridoid glycoside compound .
    6''-O-trans-Feruloylcatalpol
  • HY-N1206
    Specioside

    6-O-(E)-p-Coumaroylcatalpol

    		 Others Others
    Specioside is a novel iridoid glycoside extracted from Catalpa speciosa Warder (Bignoniaceae) .
    Specioside
  • HY-N11712
    8-Dehydroxyshanzhiside

    		Others Others
    8-Dehydroxyshanzhiside is an iridoid glycoside that can be isolated from Lamiophlomis rotata .
    8-Dehydroxyshanzhiside
  • HY-133109
    Trachelosiaside

    		Others Others
    Trachelosiaside is a natural organic compound belonging to the class of iridoid glycosides. Trachelosiaside is found in various plant species, especially in the roots of Trachelospermum jasminoides. Trachelosiaside has potential medicinal properties, such as anti-inflammatory, antioxidant, and anti-tumor effects. Trachelosiaside has industrial applications in the production of food supplements, cosmetics and pharmaceuticals.
    Trachelosiaside
  • HY-N0914R
    Ajugol (Standard)

    		Reference Standards Parasite Autophagy Interleukin Related Reactive Oxygen Species (ROS) mTOR Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Ajugol (Standard) is the analytical standard of Ajugol (HY-N0914). This product is intended for research and analytical applications. Ajugol is an orally active iridoid glycoside found in the traditional Chinese medicine Leonurus japonicus. Ajugol is an autophagy activator. Ajugol activates TFEB-mediated autophagy and lysosomal biogenesis. Ajugol also has anti-inflammatory effects. Ajugol has great potential in the research of asthma, non-alcoholic fatty liver disease (NAFLD), and osteoarthritis .
    Ajugol (Standard)
  • HY-N0820R
    Catalpol (Standard)

    Catalpinoside (Standard)

    		 Reference Standards HBV Infection Neurological Disease Inflammation/Immunology Cancer
    Catalpol (Standard) is the analytical standard of Catalpol. This product is intended for research and analytical applications. Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .
    Catalpol (Standard)
  • HY-N13109
    Caprarioside

    		Others Others
    Caprarioside is an iridoid glycoside that can be isolated from Capraria biflora L. .
    Caprarioside
  • HY-125543
    Karsoside

    		Others Others
    Karsoside is an iridoid glycoside that can be isolated from Scrophularia ilwensis .
    Karsoside
  • HY-N9352
    Cantleyoside

    		Others Others
    Cantleyoside is a natiural iridoid glycoside that could be found in the Roots of Dipsacus asper .
    Cantleyoside
  • HY-N11794
    7-Ketologanin

    		Others Others
    7-Ketologanin is an iridoid glucoside. 7-Ketologanin can be isolated from the Stems of Viburnum erosum. 7-Ketologanin involves in biosynthetic pathway of oleuropein. Oleuropein, is a bioactive phenolic compound, modulates several oncogenic signalling pathways .
    7-Ketologanin
  • HY-N2015
    Hastatoside

    		Others Neurological Disease
    Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep .
    Hastatoside
  • HY-N0409
    Picroside III
    1 Publications Verification

    		 Others Inflammation/Immunology
    Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .
    Picroside III
  • HY-N4221
    6'-​O-​Cinnamoyl harpagide

    		Others Others
    6'-O-Cinnamoyl harpagide is an iridoid glycoside isolated from the roots of Scrophularia ningpoensis .
    6'-​O-​Cinnamoyl harpagide
  • HY-N3839
    epi-Vogeloside

    7-epi-Vogeloside; Nervoside; Epivogeloside

    		 Others Others
    epi-Vogeloside is a secoiridoid glycoside and a iridoid glucoside, which can be isolated from Lonicera japonica Thunb .
    epi-Vogeloside
  • HY-N12840
    Logmalicid B

    		Interleukin Related Metabolic Disease
    Logmalicid B is an iridoid glycoside compound that can be isolated from Cornus officinalis and can be used in diabetes research .
    Logmalicid B
  • HY-N12202
    6′-O-β-D-Glucopyranosylphlorigidoside C

    		Others Others
    6′-O-β-D-Glucopyranosylphlorigidoside C (compound 1) is an iridoid glycoside that can be isolated from Lamiophlomis rotata .
    6′-O-β-D-Glucopyranosylphlorigidoside C
  • HY-N6008
    7-O-Methyl morroniside

    		Others Others
    7-O-Methyl morroniside is an iridoid glycoside (IG) extracted from Cornus officinalis fructus, used in many traditional Chinese medicines .
    7-O-Methyl morroniside
  • HY-N2015R
    Hastatoside (Standard)

    		Reference Standards Others Neurological Disease
    Hastatoside (Standard) is the analytical standard of Hastatoside. This product is intended for research and analytical applications. Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep .
    Hastatoside (Standard)
  • HY-N0494
    Gentiopicroside
    2 Publications Verification

    Gentiopicrin

    		 Cytochrome P450 HCV Inflammation/Immunology
    Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
    Gentiopicroside
  • HY-N0409R
    Picroside III (Standard)

    		Reference Standards Others Inflammation/Immunology
    Picroside III (Standard) is the analytical standard of Picroside III. This product is intended for research and analytical applications. Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .
    Picroside III (Standard)
  • HY-N2094
    Genipin 1-β-D-gentiobioside
    1 Publications Verification

    Genipin 1-gentiobioside; Genipin 1-β-gentiobioside; Genipin gentiobioside

    		 Others Inflammation/Immunology
    Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.
    Genipin 1-β-D-gentiobioside
  • HY-N15647
    Menthiafolin

    		Others Others
    Menthiafolin is an iridoid glycoside obtained from the methanol extract of Nymphoides peltata roots. Nymphoides peltata is used in traditional medicine to treat edema, and its related extracts Scopolin (HY-N0341) and Peltatamarins A have wound healing properties [1].
    Menthiafolin
  • HY-N5070
    Depressine

    Depressin

    		 Biochemical Assay Reagents Others
    Depressine is an iridoid glycoside that can be isolated from the methanol extract of the aerial parts of Gentiana depressa. Depressine can be used to reduce oxidative DNA base damage and strand breaks that are prone to occur during the preparation of silver nanoparticles (AgNPs) .
    Depressine
  • HY-N0494R
    Gentiopicroside (Standard)

    Gentiopicrin (Standard)

    		 Reference Standards Cytochrome P450 HCV Inflammation/Immunology
    Gentiopicroside (Standard) is the analytical standard of Gentiopicroside. This product is intended for research and analytical applications. Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
    Gentiopicroside (Standard)
  • HY-N3552
    Catalposide

    		NF-κB Inflammation/Immunology
    Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages .
    Catalposide
  • HY-N6246
    Asperulosidic Acid

    		NF-κB ERK Inflammation/Immunology Cancer
    Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .
    Asperulosidic Acid
  • HY-126232
    Verproside

    		NF-κB TNF Receptor IKK Infection Inflammation/Immunology
    Verproside, a catalpol derivative iridoid glycoside isolated from the genus Pseudolysimachion, represses TNF-α -induced MUC5AC expression by inhibiting NF-κB activation via the IKK/IκB signaling cascade. Verproside has potent anti-inflammatory, antioxidant, antinociceptive and anti-asthmatic activities. Verproside has the potential for the study of chronic obstructive pulmonary disease (COPD) .
    Verproside
  • HY-N0397
    Harpagide

    		Parasite Infection Inflammation/Immunology
    Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .
    Harpagide
  • HY-121125
    Aucubigenin

    		Others Others
    Aucubigenin, the aglycone of the iridoid glycoside aucubin, has been characterized through X-ray diffraction analysis. Its crystal structure reveals monoclinic symmetry with specific conformations adopted by its cyclopentane and pyran rings. The study also determined the absolute configurations of both aucubin and aucubigenin. Significant O-H O hydrogen bonding interactions were observed in the crystal lattices of both compounds, highlighting their structural stability and potential for intermolecular interactions .
    Aucubigenin
  • HY-N6246R
    Asperulosidic Acid (Standard)

    		Reference Standards NF-κB ERK Inflammation/Immunology Cancer
    Asperulosidic Acid (Standard) is the analytical standard of Asperulosidic Acid. This product is intended for research and analytical applications. Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .
    Asperulosidic Acid (Standard)
  • HY-N12203
    5-Deoxypulchelloside I

    		Others Others
    5-Deoxypulchelloside I is a magnoside glycoside that can be isolated from the aerial parts of the Lamiaceae plant Eremostachys laciniata .
    5-Deoxypulchelloside I
  • HY-N0512
    Loganin
    4 Publications Verification

    Loganoside

    		 Reactive Oxygen Species (ROS) TNF Receptor Interleukin Related Neurological Disease Inflammation/Immunology Cancer
    Loganin is a type of iridoid glycoside compound that possesses anti-inflammatory, antioxidant, and antitumor properties, and offers protective effects against acute lung injury and pulmonary fibrosis. Loganin exerts its protective effects against LPS (HY-D1056)-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI) .
    Loganin
  • HY-N0397R
    Harpagide (Standard)

    		Reference Standards Parasite Infection Inflammation/Immunology
    Harpagide (Standard) is the analytical standard of Harpagide. This product is intended for research and analytical applications. Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .
    Harpagide (Standard)
  • HY-N0512R
    Loganin (Standard)

    Loganoside (Standard)

    		 Reference Standards Apoptosis Keap1-Nrf2 TNF Receptor Interleukin Related Neurological Disease Inflammation/Immunology Cancer
    Loganin (Standard) is the analytical standard of Loganin. This product is intended for research and analytical applications. Loganin is a type of iridoid glycoside compound that possesses anti-inflammatory, antioxidant, and antitumor properties, and offers protective effects against acute lung injury and pulmonary fibrosis. Loganin exerts its protective effects against LPS (HY-D1056)-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI) .
    Loganin (Standard)
  • HY-N0648
    Monotropein
    1 Publications Verification

    		 Interleukin Related Keap1-Nrf2 Heme Oxygenase (HO) NF-κB Apoptosis Inflammation/Immunology
    Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
    Monotropein
  • HY-N0648R
    Monotropein (Standard)

    		Reference Standards Interleukin Related Heme Oxygenase (HO) Keap1-Nrf2 NF-κB Apoptosis Inflammation/Immunology
    Monotropein (Standard) is the analytical standard of Monotropein. This product is intended for research and analytical applications. Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
    Monotropein (Standard)
  • HY-N0806
    Sweroside
    1 Publications Verification

    		 Keap1-Nrf2 AMPK Sirtuin NF-κB NOD-like Receptor (NLR) Pyroptosis Apoptosis Autophagy PARP Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields .
    Sweroside
  • HY-N0806R
    Sweroside (Standard)

    		Reference Standards Keap1-Nrf2 AMPK Sirtuin NF-κB NOD-like Receptor (NLR) Pyroptosis Apoptosis Autophagy PARP Metabolic Disease
    Sweroside (Standard) is the analytical standard of Sweroside (HY-N0806). This product is intended for research and analytical applications. Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields .
    Sweroside (Standard)

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