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Results for "

hypoglycemic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (3) Akt (2) Aldose Reductase (1) AMPK (2) Apoptosis (9) Autophagy (4) Bacterial (3) Biochemical Assay Reagents (1) Calcium Channel (1) COX (4) Cytochrome P450 (4) Dipeptidyl Peptidase (3) Drug Derivative (1) Drug Metabolite (2) Endogenous Metabolite (11) ERK (3) FAK (2) Free Fatty Acid Receptor (1) Fungal (3) G protein-coupled Bile Acid Receptor 1 (2) GCGR (4) Gli (1) GLP Receptor (1) GLUT (4) Glycosidase (15) GPR119 (1) HBV (3) HIF/HIF Prolyl-Hydroxylase (2) HIV (1) Influenza Virus (4) Insulin Receptor (3) Integrin (2) Interleukin Related (2) Isotope-Labeled Compounds (2) JAK (3) JNK (3) Keap1-Nrf2 (3) Mitochondrial Metabolism (2) MMP (2) Na+/K+ ATPase (2) NF-κB (9) p38 MAPK (4) Parasite (2) PEPCK (1) PERK (2) Phosphatase (8) PI3K (1) PKA (1) Potassium Channel (3) PPAR (7) Reactive Oxygen Species (2) Reference Standards (7) ROS Kinase (2) SOD (2) TGF-beta/Smad (1) TRP Channel (1)
By Research Areas:	Cancer (28) Cardiovascular Disease (14) Endocrinology (10) Infection (16) Inflammation/Immunology (32) Metabolic Disease (78) Neurological Disease (14)

By Targets:

Adrenergic Receptor (3)

Akt (2)

Aldose Reductase (1)

AMPK (2)

Apoptosis (9)

Autophagy (4)

Bacterial (3)

Biochemical Assay Reagents (1)

Calcium Channel (1)

COX (4)

Cytochrome P450 (4)

Dipeptidyl Peptidase (3)

Drug Derivative (1)

Drug Metabolite (2)

Endogenous Metabolite (11)

ERK (3)

FAK (2)

Free Fatty Acid Receptor (1)

Fungal (3)

G protein-coupled Bile Acid Receptor 1 (2)

GCGR (4)

Gli (1)

GLP Receptor (1)

GLUT (4)

Glycosidase (15)

GPR119 (1)

HBV (3)

HIF/HIF Prolyl-Hydroxylase (2)

HIV (1)

Influenza Virus (4)

Insulin Receptor (3)

Integrin (2)

Interleukin Related (2)

Isotope-Labeled Compounds (2)

JAK (3)

JNK (3)

Keap1-Nrf2 (3)

Mitochondrial Metabolism (2)

MMP (2)

Na+/K+ ATPase (2)

NF-κB (9)

p38 MAPK (4)

Parasite (2)

PEPCK (1)

PERK (2)

Phosphatase (8)

PI3K (1)

PKA (1)

Potassium Channel (3)

PPAR (7)

Reactive Oxygen Species (2)

Reference Standards (7)

ROS Kinase (2)

SOD (2)

TGF-beta/Smad (1)

TRP Channel (1)

By Research Areas:

Cancer (28)

Cardiovascular Disease (14)

Endocrinology (10)

Infection (16)

Inflammation/Immunology (32)

Metabolic Disease (78)

Neurological Disease (14)

106

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7910

Stachyose	Endogenous Metabolite	Metabolic Disease
Stachyose, a kind of oligosaccharides, act as a hypoglycemic agent .

HY-Y0004

2-Pyridinemethanol	Drug Derivative	Metabolic Disease
2-Pyridinemethanol is a pyridylalcohol, with hypoglycemic activity .

HY-15383

Glyparamide	Others	Others
Glyparamide is an orally active chlorophenyl-containing sulfonylurea. Glyparamide shows hypoglycemic activity and rarely causes hepatic injury .

HY-W011651

Carbutamide BZ-55	Phosphatase	Metabolic Disease
Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity .

HY-170692

Hypoglycemic agent 3	Akt PI3K NF-κB	Metabolic Disease
Hypoglycemic agent 3 (Compound H26), a derivative of corosolic acid, exhibits lipid-lowering and significant hypoglycemic effects and can be used as a hypoglycemic agent. Hypoglycemic agent 3 inhibits insulin resistance by targeting MCCC1 and can be used in the study of type 2 diabetes .

HY-130003

Hypoglycemic agent 1	Others	Metabolic Disease
Hypoglycemic agent 1 acts as a therapeutic and/or prophylactic agent for diabetes. Hypoglycemic agent 1 has an action for lowering blood sugar .

HY-N7910R

Stachyose (Standard)	Endogenous Metabolite	Metabolic Disease
Stachyose (Standard) is the analytical standard of Stachyose. This product is intended for research and analytical applications. Stachyose, a kind of oligosaccharides, act as a hypoglycemic agent[1].

HY-N3613

Conduritol A	Others	Metabolic Disease
Conduritol A is a hypoglycemic agent which inhibits the absorption of glucose and can be extracted from Gymnema sylvestre .

HY-135670B

Glycosidase-IN-2	Glycosidase	Metabolic Disease
Glycosidase-IN-2 (Compound 20) is an azasugar class of glycosidase inhibitor. Glycosidase-IN-2 has hypoglycemic activity .

HY-135670A

β-glycosidase-IN-1	Glycosidase	Metabolic Disease
β-glycosidase-IN-1 (Compound 33) is a piperidine derivative and a β-glycosidase inhibitor. β-glycosidase-IN-1 has hypoglycemic activity .

HY-N12241

Sterebin F	Others	Others
Sterebin F is a steroid isolated from the Stevia rebaudiana leaves. Sterebin F has hypoglycemic activity .

HY-162893

SX29	Glycosidase	Metabolic Disease
SX29 is an orally active non-competitive α-glucosidase inhibitor with an IC₅₀ value of 2.12 μM. SX29 exhibits hypoglycemic activity, and oral administration of SX29 can reduce blood glucose levels and improve glucose tolerance in diabetic mice .

HY-101048

Synthalin A sulfate	Bacterial	Infection Metabolic Disease
Synthalin A sulfate is a biguanylated diamine with antibacterial and hypoglycemic properties. Synthalin A sulfate against S. aureus with a MIC of 64 μg/mL .

HY-N7377

Butyl isobutyl phthalate	Glycosidase	Metabolic Disease
Butyl isobutyl phthalate is isolated from the rhizoid of Laminaria japonica. Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor with an IC₅₀ value of 38 μM. Butyl isobutyl phthalate shows a hypoglycemic effect and has the potential for diabetes treatment .

HY-N4147

Eleutheroside D	Others	Metabolic Disease Inflammation/Immunology
Eleutheroside D is an active lignan isolated from the root of Eleutherococcus senticosus, has anti-inflammatory and hypoglycemic activities . Eleutheroside D is an optical isomer of Eleutheroside E (HY-N0272) .

HY-W011651R

Carbutamide (Standard) BZ-55 (Standard)	Phosphatase Reference Standards	Metabolic Disease
Carbutamide (Standard) is the analytical standard of Carbutamide. This product is intended for research and analytical applications. Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity .

HY-113631

Amorfrutin B	PPAR	Neurological Disease Metabolic Disease
Amorfrutin B is a highly potent natural peroxisome proliferation-activated receptor γ (PPARγ) agonist with oral activity with K_i values of 19 nM and EC₅₀ values of 73 nM, respectively. Amorfrutin B has hypoglycemic and neuroprotective activities .

HY-170588

α-Glucosidase-IN-78	Glycosidase	Metabolic Disease
α-Glucosidase-IN-78 (Compound 12m) is an inhibitor for α-glucosidase with a reversible, competitive IC₅₀ 6.0 μM. α-Glucosidase-IN-78 can be used in research of diabete for its hypoglycemic property .

HY-163652

Glicetanile	Others	Metabolic Disease
Glicetanile is an orally active hypoglycemic agent, that stimulates the release of insulin from pancreatic beta cells, and lowers the blood sugar. Glicetanile exhibits potential in ameliorating the type 2 diabetes .

HY-N12647

cis-Hinkiresinol	Others	Infection Inflammation/Immunology
cis-Hinkiresinol is a bioactive constituent of Rhizoma anemarrhenae. Rhizoma anemarrhenae is reprted to have anti-pathogenic microorganism, hypoglycemic effects, anti-inflammatory, antipyretic effects and anti-platelet aggregation .

HY-135670

Glycosidase-IN-1	Glycosidase	Metabolic Disease
Glycosidase-IN-1 (Compound 9) is a glycosidase inhibitor synthesized from D-mannose. Glycosidase-IN-1 be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors. Glycosidase-IN-1 has hypoglycemic activity .

HY-128574

GLUT4 activator 1	GLUT	Metabolic Disease
GLUT4 activator 1 (Compound 26b) is an orally active glucose transporter type 4 (GLUT4) translocation activator with an EC₅₀ of 0.14 μM. GLUT4 activator 1 has a hypoglycemic effect. GLUT4 activator 1 can be used in diabetes research .

HY-121565

SaRI 59-801	Insulin Receptor	Metabolic Disease Endocrinology
SaRI 59-801 is an orally effective hypoglycemic compound with stimulation activity of insulin secretion. SaRI 59-801 decreases blood glucose in several species and to elevate plasma insulin in rats and mice .

HY-N11840

Mortatarin F	Glycosidase	Metabolic Disease
Mortatarin F (Compound 1) is an inhibitor of α‑glucosidase with an IC₅₀ of 8.7 μΜ. Mortatarin F is an renylated flavonoid that can be isolated from mulberry leaves and can be used for hypoglycemic research .

HY-168706

LXQ-87	Phosphatase	Metabolic Disease
LXQ-87 is an oral noncompetitive inhibitor of PTP1B with an IC₅₀ of 1.061 μM, showing hypoglycemic activity. LXQ-87 alleviates insulin resistance and promotes cellular glucose uptake, making it useful for research on type 2 diabetes .

HY-N0661

Alliin	Others	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Alliin, an orally active sulfoxide compound that can be isolated from garlic, exhibits hypoglycemic, antioxidant, anti-inflammatory and antitumor activities .

HY-122943

Moracin D	Fungal Apoptosis	Infection Cancer
Moracin D is a flavonoid that can be isolated from Morus alba. Moracin D induces cell apoptosis and shows hypoglycemic, antiadipogenic, antifungal and antitumor effects. Moracin D can be used for fungal infection and breast cancer research .

HY-126067

(-)-Pinoresinol	Glycosidase Apoptosis	Inflammation/Immunology
(-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest .

HY-156830A

(4′R)-TGR5 Receptor Agonist 4	G protein-coupled Bile Acid Receptor 1	Metabolic Disease
(4′R)-TGR5 Receptor Agonist 4 is the R enantiomer of TGR5 Receptor Agonist 4 (HY-156830). TGR5 Receptor Agonist 4 is an agonist of Bile Acid Receptor (TGR5), with EC₅₀ for hTGR5 and mTGR5 of 2 nM and 3 nM, respectively. TGR5 Receptor Agonist 4 plays important roles in hypoglycemic and weight loss .

HY-128923

SKF-34288 hydrochloride 5+ Cited Publications 3-Mercaptopicolinic acid hydrochloride; 3-MPA hydrochloride	PEPCK	Metabolic Disease
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (K_i: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides .

HY-N0820

Catalpol Maximum Cited Publications 10 Publications Verification Catalpinoside	HBV	Infection Neurological Disease Inflammation/Immunology Cancer
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-Y0624

4-Pentenoic acid	Endogenous Metabolite Mitochondrial Metabolism	Metabolic Disease
4-Pentenoic acid is a medium-chain unsaturated fatty acid. 4-Pentenoic acid has hypoglycemic and fatty acid oxidation inhibitory activities. 4-Pentenoic acid can affect blood glucose metabolism and energy metabolism through mechanisms such as inhibiting long-chain fatty acid oxidation, reducing gluconeogenesis, and promoting glucose utilization .

HY-N0661R

Alliin (Standard)	Others	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Alliin (Standard) is the analytical standard of Alliin. This product is intended for research and analytical applications. Alliin, an orally active sulfoxide compound that can be isolated from garlic, exhibits hypoglycemic, antioxidant, anti-inflammatory and antitumor activities .

HY-172811

DA-302168S	GCGR	Metabolic Disease
DA-302168S is an orally active and selective agonist targeting the GLP-1R, with EC₅₀ value of 1.32 nM. DA-302168S stimulates insulin secretion and shows hypoglycemic effects. DA-302168S decreases food intake. DA-302168S mainly activates GLP-1R of monkeys and humans, and exhibits little excitatory effect on GLP-1R of rats, mice, and dogs. DA-302168S can be used for type 2 diabetes and obesity study .

HY-N8264

Moringin 1 Publications Verification	TRP Channel	Neurological Disease Inflammation/Immunology Cancer
Moringin is a potent and selective TRPA1 ion channel natural agonist with an EC₅₀ of 3.14 μM. Moringin does not activate or activates very weakly the vanilloids somatosensory channels TRPV1, TRPV2, TRPV3 and TRPV4, and the melastatin cooling receptor TRPM8. Moringin has hypoglycemic, antimicrobial, anti-inflammatory, anticancer and neuroprotection activities .

HY-N5086

Picroside IV	HBV	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-N0820R

Catalpol (Standard)	HBV	Infection Neurological Disease Inflammation/Immunology Cancer
Catalpol (Standard) is the analytical standard of Catalpol. This product is intended for research and analytical applications. Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-172120

GPR119 agonist 3	GPR119	Metabolic Disease
GPR119 agonist 3 (Compound 21b) is an orally active agonist of GPR119 with an EC₅₀ value of 3.8 nM for hGPR119. Additionally, GPR119 agonist 3 exhibits hypoglycemic effects and can be used in research on type 2 diabetes and obesity .

HY-128447

Allyl methyl sulfide	Endogenous Metabolite SOD NF-κB GLUT	Metabolic Disease Inflammation/Immunology
Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications .

HY-W011220

Ciglitazone 1 Publications Verification ADD-3878; U-63287	PPAR	Cardiovascular Disease Cancer
Ciglitazone is a potent and selective PPARγ agonist (EC₅₀=3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells .

HY-128447R

Allyl methyl sulfide (Standard)	Reference Standards Endogenous Metabolite SOD NF-κB GLUT	Metabolic Disease Inflammation/Immunology
Allyl methyl sulfide (Standard) is the analytical standard of Allyl methyl sulfide (HY-128447). This product is intended for research and analytical applications. Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications .

HY-150723

PBI-6DNJ	Glycosidase	Metabolic Disease
PBI-6DNJ is an orally active and potent multivalent glycosidase inhibitor. PBI-6DNJ exhibits good inhibition activity against α-glucosidase from mice, with a K_i of 0.14 μM. PBI-6DNJ exhibits good hypoglycemic activity. PBI-6DNJ can be used for type 2 diabetes research .

HY-N0416

Cucurbitacin B 5+ Cited Publications	HIF/HIF Prolyl-Hydroxylase Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX	Others Neurological Disease Inflammation/Immunology Cancer
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-N0926A

Columbamine chloride 1 Publications Verification Columbamin chloride; Dehydroisocorypalmine chloride	Cytochrome P450 Apoptosis Parasite	Infection Neurological Disease Inflammation/Immunology Cancer
Columbamine (Columbamin; Dehydroisocorypalmine) chloride is an organic heterotetracyclic alkaloid extracted from plants. Columbamine chloride is a metabolite of Berberine (HY-N0716). Columbamine chloride inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 30.6 µM). Columbamine chloride induces apoptosis in cancer cells. Columbamine chloride can be used for antioxidant, anti-inflammatory, antitumor, antifungal, antiparasite, hepatoprotective, neuroprotective, hypolipidemic and hypoglycemic study .

HY-N0926

Columbamine 1 Publications Verification Columbamin; Dehydroisocorypalmine	Cytochrome P450 Apoptosis Parasite	Infection Neurological Disease Inflammation/Immunology Cancer
Columbamine (Columbamin; Dehydroisocorypalmine) is an organic heterotetracyclic alkaloid extracted from plants. Columbamine is a metabolite of Berberine (HY-N0716). Columbamine inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 30.6 µM). Columbamine induces apoptosis in cancer cells. Columbamine can be used for antioxidant, anti-inflammatory, antitumor, antifungal, antiparasite, hepatoprotective, neuroprotective, hypolipidemic and hypoglycemic study .

HY-U00012

Glyhexamide SQ 15860; Serbose; Subose	Others	Metabolic Disease
Glyhexamide is an effective hypoglycemic agent in adult diabetics.

HY-N0416R

Cucurbitacin B (Standard)	HIF/HIF Prolyl-Hydroxylase Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX	Others Neurological Disease Inflammation/Immunology Cancer
Cucurbitacin B (Standard) is the analytical standard of Cucurbitacin B. This product is intended for research and analytical applications. Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-173217

PPARα agonist 5	PPAR Phosphatase	Cardiovascular Disease Metabolic Disease
PPARα agonist 5 is an orally available, selective partial agonist of PPARα (EC₅₀: 3 nM). PPARα agonist 5 reduces lipid accumulation and upregulates key PPARα target genes, exerting anti-fatty liver effects. PPARα agonist 5 also exhibits significant hypolipidemic and hypoglycemic effects through partial PPARγ agonist activity and mild inhibition of protein tyrosine phosphatase 1B (PTP1B) (IC₅₀: 79.1 μM). PPARα agonist 5 has a good safety profile and can be used in the study of type 2 diabetes with dyslipidemia .

HY-B1103

Hydroxyhexamide (±)-Hydroxyhexamid	Drug Metabolite	Cardiovascular Disease
Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents.

HY-B0920

Tolazamide U-17835	Calcium Channel	Endocrinology
Tolazamide is an oral hypoglycemic agent used in the study of type 2 diabetes.

Cat. No.	Product Name	Target	Research Area

HY-P4860

Adropin (34-76) (human, mouse, rat)	Akt Gli JNK PKA	Metabolic Disease
Adropin (34-76) is a secretory domain of Adropin. Adropin (34-76) can inhibit cAMP level and glucose production in hepatocytes, and has a hypoglycemic effect. Adropin (34-76) plays an antifibrotic role by inhibiting the GLI1 signaling pathway .

HY-P3580A

Acetyl Gastric Inhibitory Peptide (human) (TFA) Human N-acetyl GIP TFA	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research of diabetes, insulin resistance and obesity .

HY-P10312

SPN009	GLP Receptor	Metabolic Disease
SPN009 (Sequence 3) is a GLP-1 Receptor agonist, with EC₅₀ of 2.84 nM. SPN009 attenuates the type II diabetes in DB/DB mice models .

HY-P3580

Acetyl Gastric Inhibitory Peptide (human) Human N-acetyl GIP	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7910

Stachyose	Structural Classification Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Albizia glaberrima (Schumach. & Thonn.) Benth. Human Gut Microbiota Metabolites Polysaccharides Microorganisms Labiatae Disease Research Fields Saccharides	Endogenous Metabolite
Stachyose, a kind of oligosaccharides, act as a hypoglycemic agent .

HY-N7377

Butyl isobutyl phthalate	Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields	Glycosidase
Butyl isobutyl phthalate is isolated from the rhizoid of Laminaria japonica. Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor with an IC₅₀ value of 38 μM. Butyl isobutyl phthalate shows a hypoglycemic effect and has the potential for diabetes treatment .

HY-N0661

Alliin	Cardiovascular Disease Structural Classification Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields A．Sativam L. var．Viviparum Regel	Others
Alliin, an orally active sulfoxide compound that can be isolated from garlic, exhibits hypoglycemic, antioxidant, anti-inflammatory and antitumor activities .

HY-N7910R

Stachyose (Standard)	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Microorganisms Labiatae Source classification Plants Endogenous metabolite Albizia glaberrima (Schumach. & Thonn.) Benth. Saccharides	Endogenous Metabolite
Stachyose (Standard) is the analytical standard of Stachyose. This product is intended for research and analytical applications. Stachyose, a kind of oligosaccharides, act as a hypoglycemic agent[1].

HY-N3613

Conduritol A	Structural Classification Natural Products Source classification Asclepiadaceae Plants Gymnema sylvestre (Retz.) Schult.	Others
Conduritol A is a hypoglycemic agent which inhibits the absorption of glucose and can be extracted from Gymnema sylvestre .

HY-N12241

Sterebin F	Structural Classification Terpenoids Source classification Cassia Diterpenoids Plants Compositae	Others
Sterebin F is a steroid isolated from the Stevia rebaudiana leaves. Sterebin F has hypoglycemic activity .

HY-N4147

Eleutheroside D	Classification of Application Fields Source classification Lignans Phenylpropanoids Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Disease Research Fields Inflammation/Immunology Araliaceae	Others
Eleutheroside D is an active lignan isolated from the root of Eleutherococcus senticosus, has anti-inflammatory and hypoglycemic activities . Eleutheroside D is an optical isomer of Eleutheroside E (HY-N0272) .

HY-113631

Amorfrutin B	Structural Classification Monophenols Leguminosae Source classification Phenols Amorpha fruticosaL. Plants	PPAR
Amorfrutin B is a highly potent natural peroxisome proliferation-activated receptor γ (PPARγ) agonist with oral activity with K_i values of 19 nM and EC₅₀ values of 73 nM, respectively. Amorfrutin B has hypoglycemic and neuroprotective activities .

HY-N12647

cis-Hinkiresinol	Structural Classification Liliaceae Source classification Phenols Polyphenols Anemarrhena asphodeloides Bunge Plants	Others
cis-Hinkiresinol is a bioactive constituent of Rhizoma anemarrhenae. Rhizoma anemarrhenae is reprted to have anti-pathogenic microorganism, hypoglycemic effects, anti-inflammatory, antipyretic effects and anti-platelet aggregation .

HY-N11840

Mortatarin F	Structural Classification Flavanonols Flavonoids Source classification Phenols Polyphenols Morus alba L. Plants Moraceae	Glycosidase
Mortatarin F (Compound 1) is an inhibitor of α‑glucosidase with an IC₅₀ of 8.7 μΜ. Mortatarin F is an renylated flavonoid that can be isolated from mulberry leaves and can be used for hypoglycemic research .

HY-122943

Moracin D	Structural Classification Natural Products Source classification Morus alba L. Plants Moraceae	Fungal Apoptosis
Moracin D is a flavonoid that can be isolated from Morus alba. Moracin D induces cell apoptosis and shows hypoglycemic, antiadipogenic, antifungal and antitumor effects. Moracin D can be used for fungal infection and breast cancer research .

HY-126067

(-)-Pinoresinol	Structural Classification other families Hernandia nymphaeifolia (C. Presl) Kubitzki Source classification Lignans Phenylpropanoids Plants	Glycosidase Apoptosis
(-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest .

HY-N0820

Catalpol Maximum Cited Publications 10 Publications Verification Catalpinoside	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Infection Iridoids Terpenoids Scrophulariaceae Inflammation/Immunology Disease Research Fields Cancer	HBV
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-Y0624

4-Pentenoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Mitochondrial Metabolism
4-Pentenoic acid is a medium-chain unsaturated fatty acid. 4-Pentenoic acid has hypoglycemic and fatty acid oxidation inhibitory activities. 4-Pentenoic acid can affect blood glucose metabolism and energy metabolism through mechanisms such as inhibiting long-chain fatty acid oxidation, reducing gluconeogenesis, and promoting glucose utilization .

HY-N0661R

Alliin (Standard)	Structural Classification Liliaceae Ketones, Aldehydes, Acids Source classification Plants A．Sativam L. var．Viviparum Regel	Others
Alliin (Standard) is the analytical standard of Alliin. This product is intended for research and analytical applications. Alliin, an orally active sulfoxide compound that can be isolated from garlic, exhibits hypoglycemic, antioxidant, anti-inflammatory and antitumor activities .

HY-N8264

Moringin 1 Publications Verification	Structural Classification Natural Products Neurological Disease Classification of Application Fields Moringa oleifera Lam. Source classification Moringaceae Plants Inflammation/Immunology Disease Research Fields	TRP Channel
Moringin is a potent and selective TRPA1 ion channel natural agonist with an EC₅₀ of 3.14 μM. Moringin does not activate or activates very weakly the vanilloids somatosensory channels TRPV1, TRPV2, TRPV3 and TRPV4, and the melastatin cooling receptor TRPM8. Moringin has hypoglycemic, antimicrobial, anti-inflammatory, anticancer and neuroprotection activities .

HY-N5086

Picroside IV	Structural Classification Neurological Disease Classification of Application Fields Source classification Metabolic Disease Plants Monophenols Iridoids Terpenoids Phenols Scrophulariaceae Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields	HBV
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-N0820R

Catalpol (Standard)	Structural Classification Iridoids Terpenoids Source classification Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey	HBV
Catalpol (Standard) is the analytical standard of Catalpol. This product is intended for research and analytical applications. Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-128447

Allyl methyl sulfide	Infection Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields A．Sativam L. var．Viviparum Regel	Endogenous Metabolite SOD NF-κB GLUT
Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications .

HY-128447R

Allyl methyl sulfide (Standard)	Structural Classification Natural Products Liliaceae Source classification Plants Endogenous metabolite A．Sativam L. var．Viviparum Regel	Reference Standards Endogenous Metabolite SOD NF-κB GLUT
Allyl methyl sulfide (Standard) is the analytical standard of Allyl methyl sulfide (HY-128447). This product is intended for research and analytical applications. Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications .

HY-N0416

Cucurbitacin B 5+ Cited Publications	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Cucurbitaceae Trichosanthes cucumerina L. Plants Endogenous metabolite Disease Research Fields Cancer	HIF/HIF Prolyl-Hydroxylase Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-N0926A

Columbamine chloride 1 Publications Verification Columbamin chloride; Dehydroisocorypalmine chloride	Structural Classification Alkaloids Mahonia bealei (Fort.) Carr. Source classification Quinoline Alkaloids Plants Berberidaceae	Cytochrome P450 Apoptosis Parasite
Columbamine (Columbamin; Dehydroisocorypalmine) chloride is an organic heterotetracyclic alkaloid extracted from plants. Columbamine chloride is a metabolite of Berberine (HY-N0716). Columbamine chloride inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 30.6 µM). Columbamine chloride induces apoptosis in cancer cells. Columbamine chloride can be used for antioxidant, anti-inflammatory, antitumor, antifungal, antiparasite, hepatoprotective, neuroprotective, hypolipidemic and hypoglycemic study .

HY-N0926

Columbamine 1 Publications Verification Columbamin; Dehydroisocorypalmine	Alkaloids Structural Classification Monophenols other families Classification of Application Fields Source classification Other Diseases Phenols Plants Isoquinoline Alkaloids Disease Research Fields	Cytochrome P450 Apoptosis Parasite
Columbamine (Columbamin; Dehydroisocorypalmine) is an organic heterotetracyclic alkaloid extracted from plants. Columbamine is a metabolite of Berberine (HY-N0716). Columbamine inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 30.6 µM). Columbamine induces apoptosis in cancer cells. Columbamine can be used for antioxidant, anti-inflammatory, antitumor, antifungal, antiparasite, hepatoprotective, neuroprotective, hypolipidemic and hypoglycemic study .

HY-N0416R

Cucurbitacin B (Standard)	Triterpenes Structural Classification Terpenoids Source classification Cucurbitaceae Trichosanthes cucumerina L. Plants Endogenous metabolite	HIF/HIF Prolyl-Hydroxylase Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX
Cucurbitacin B (Standard) is the analytical standard of Cucurbitacin B. This product is intended for research and analytical applications. Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-N6653

Lentinan 5 Publications Verification	Structural Classification Polysaccharides Agaricaceae Classification of Application Fields Source classification Lentinus edodes (Berk. ) Sing Plants Disease Research Fields Saccharides Cancer	JAK Keap1-Nrf2 Apoptosis
Lentinan is an orally active biocompatible multifunctional polysaccharide with biological activities such as anti-inflammatory, antioxidant, immune regulation, anti-tumor, hypoglycemic, and lipid-lowering ^[1][4].

HY-105935

Keracyanin chloride Cyanidin 3-rutinoside chloride; Cyanidin 3-O-rutinoside chloride; Sambucin chloride	Structural Classification Anthocyans Flavonoids Liliaceae Classification of Application Fields Source classification Other Diseases Phenols Polyphenols Plants Smilax aspera Linn. Disease Research Fields	NF-κB PPAR Reactive Oxygen Species FAK p38 MAPK ERK JNK
Keracyanin chloride inhibits NF-κB/FAK/MAPK signaling pathway. Keracyanin chloride exhibits antioxidant, anti-inflammatory and hypoglycemic effects, and is orally active .

HY-N0205

Pulchinenoside C 1 Publications Verification Anemoside B4	Triterpenes Structural Classification Classification of Application Fields Terpenoids Ranunculaceae Source classification Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel Cancer	Others
Pulchinenoside C (Anemoside B4) is Pulsatilla koreana Nakai that have many numerous biological effects in vitro, including enhancing hypoglycemic, anti-tumor, neuroprotective and anti-angiogenic activity.

HY-B0089

Acarbose 3 Publications Verification BAY g 5421	Structural Classification Polysaccharides Microorganisms Classification of Application Fields Anti-aging Source classification Metabolic Disease Disease Research Fields Saccharides	Glycosidase
Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC₅₀=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .

HY-N2000

Bellidifolin	Infection Structural Classification Xanthones Classification of Application Fields Source classification Swertia bimaculata (Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark Gentianaceae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	HIV
Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities . Bellidifolin also acts as a viral protein R (Vpr) inhibitor .

HY-B0089A

Acarbose sulfate Bay-g 5421 sulfate	Structural Classification Polysaccharides Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields Saccharides	Glycosidase
Acarbose (BAY g 5421) sulfate, antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC₅₀=11 nM). Acarbose sulfate can potentiate the hypoglycemic effects of sulfonylureas or insulin .

HY-N0807R

Swertiamarin (Standard)	Structural Classification Monophenols other families Phenols Zanthoxylum chiloperone var. angustifolium Plants	MMP NF-κB JAK Keap1-Nrf2
Swertiamarin (Standard) is the analytical standard of Swertiamarin. This product is intended for research and analytical applications. Swertiamarin is an orally active iridoid compound with hypoglycemic, hypolipidemic, anti rheumatic and antioxidant activities, which can be used in the research of diabetes and arthritis .

HY-105935R

Keracyanin chloride (Standard) Cyanidin 3-rutinoside chloride (Standard); Cyanidin 3-O-rutinoside chloride (Standard); Sambucin chloride (Standard)	Structural Classification Anthocyans Flavonoids Liliaceae Source classification Phenols Polyphenols Plants Smilax aspera Linn.	Reference Standards NF-κB PPAR Reactive Oxygen Species FAK p38 MAPK ERK JNK
Keracyanin (chloride) (Standard) is the analytical standard of Keracyanin (chloride). This product is intended for research and analytical applications. Keracyanin chloride inhibits NF-κB/FAK/MAPK signaling pathway. Keracyanin chloride exhibits antioxidant, anti-inflammatory and hypoglycemic effects, and is orally active .

HY-B0089R

Acarbose (Standard)	Structural Classification Polysaccharides Microorganisms Source classification Saccharides	Glycosidase
Acarbose (Standard) is the analytical standard of Acarbose. This product is intended for research and analytical applications. Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .

HY-N0655

D-Pinitol 3-O-Methyl-D-chiro-inositol	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Leguminosae Glycine max (L.) merr Source classification Plants Inflammation/Immunology Disease Research Fields	Influenza Virus
D-pinitol (3-O-Methyl-D-chiro-inositol) is a natural compound presented in several plants, like Pinaceae and Leguminosae plants. D-pinitol exerts hypoglycemic activity and protective effects in the cardiovascular system . D-pinitol has antiviral and larvicidal activities .

HY-N0761

Isoferulic acid 3-Hydroxy-4-methoxycinnamic acid	Structural Classification Classification of Application Fields Ranunculaceae Source classification Metabolic Disease Cimicifuga foetida Linn. Plants Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Disease Research Fields Endocrinology	Adrenergic Receptor Influenza Virus
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes .

HY-N0299

Stachyose hydrate	Structural Classification Polysaccharides Classification of Application Fields Source classification Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Inflammation/Immunology Disease Research Fields Saccharides	Endogenous Metabolite Apoptosis
Stachyose hydrate is an orally active prebiotic that enhances the growth and activity of beneficial bacteria. Stachyose hydrate has hypoglycemic effects and can improve inflammation by regulating gut microbiota. In addition, Stachyose hydrate can induce plant cell apoptosis (Apoptosis). Stachyose hydrate can be used in research on inflammation, gastrointestinal diseases, and agriculture .

HY-N2229

Rhapontigenin 2 Publications Verification	Infection Structural Classification Stilbenes Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Trigonella foenum-graecum Linn. Inflammation/Immunology Disease Research Fields	Cytochrome P450 Fungal Bacterial
Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC₅₀ = 400 nM). Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively .

HY-N2229R

Rhapontigenin (Standard)	Structural Classification Stilbenes Leguminosae Source classification Phenols Polyphenols Plants Trigonella foenum-graecum Linn.	Cytochrome P450 Fungal Bacterial
Rhapontigenin (Standard) is the analytical standard of Rhapontigenin. This product is intended for research and analytical applications. Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC₅₀ = 400 nM). Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively .

HY-N0655R

D-Pinitol (Standard)	Structural Classification Natural Products Leguminosae Glycine max (L.) merr Source classification Plants	Influenza Virus
D-Pinitol (Standard) is the analytical standard of D-Pinitol. This product is intended for research and analytical applications. D-pinitol (3-O-Methyl-D-chiro-inositol) is a natural compound presented in several plants, like Pinaceae and Leguminosae plants. D-pinitol exerts hypoglycemic activity and protective effects in the cardiovascular system . D-pinitol has antiviral and larvicidal activities .

HY-N7241

Saudin	Clutia lanceolata Forssk. Structural Classification Other Monoterpenes Terpenoids Source classification Euphorbiaceae Plants	Others
Saudin, derived from Clutia lanceolata, is a hypoglycemic compound that significantly enhances glucose-triggered insulin release from murine pancreatic islets. It belongs to a group of new diterpenoids with a distinct tetracyclic core, suggesting potential as a therapeutic agent for diabetes treatment. Proposed biosynthetic pathways outline alternative cyclization routes from a common precursor, with Lanceolide P (16) identified as a promising lead compound for further development in managing diabetes .

HY-N5083

Saponarin 1 Publications Verification	Structural Classification Flavonoids Classification of Application Fields Flavones Dipsacaceae Dipsacus sativus (Linn.) Honck. Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	PERK NF-κB p38 MAPK AMPK Interleukin Related COX
Saponarin is an orally active flavonoid compound. Saponarin can be isolated from Gypsophila trichotoma. Saponarin inhibits ERK/p38, NF-κB and MAPK phosphorylation and activates AMPK. Saponarin reduces IL-1β and COX-2. Saponarin has antioxidant, anti-inflammatory, hepatoprotective, hypoglycemic and hypotensive effects. Saponarin improves sleep disorders .

HY-N0761R

Isoferulic acid (Standard) 3-Hydroxy-4-methoxycinnamic acid (Standard)	Structural Classification Monophenols Simple Phenylpropanols Ranunculaceae Source classification Phenols Phenylpropanoids Cimicifuga foetida Linn. Plants	Adrenergic Receptor Influenza Virus
Isoferulic acid (Standard) (3-Hydroxy-4-methoxycinnamic acid (Standard)) is the analytical standard of Isoferulic acid (HY-N0761). This product is intended for research and analytical applications. Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes .

HY-Y0337

L-Cysteine 5+ Cited Publications Cysteine	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite ERK
L-Cysteine (Cysteine) is an orally active conditionally essential amino acid with hypoglycemic effects, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans. L-Cysteine can be used as an anorectic agent .

HY-Y0624R

4-Pentenoic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Mitochondrial Metabolism
4-Pentenoic acid (Standard) is the analytical standard of 4-Pentenoic acid (HY-Y0624). This product is intended for research and analytical applications. 4-Pentenoic acid is a medium-chain unsaturated fatty acid. 4-Pentenoic acid has hypoglycemic and fatty acid oxidation inhibitory activities. 4-Pentenoic acid can affect blood glucose metabolism and energy metabolism through mechanisms such as inhibiting long-chain fatty acid oxidation, reducing gluconeogenesis, and promoting glucose utilization.

HY-N5083R

Saponarin (Standard)	Structural Classification Flavonoids Flavones Dipsacaceae Dipsacus sativus (Linn.) Honck. Source classification Phenols Polyphenols Plants	Reference Standards PERK NF-κB p38 MAPK AMPK Interleukin Related COX
Saponarin (Standard) is the analytical standard of Saponarin (HY-N5083). This product is intended for research and analytical applications. Saponarin is an orally active flavonoid compound. Saponarin can be isolated from Gypsophila trichotoma. Saponarin inhibits ERK/p38, NF-κB and MAPK phosphorylation and activates AMPK. Saponarin reduces IL-1β and COX-2. Saponarin has antioxidant, anti-inflammatory, hepatoprotective, hypoglycemic and hypotensive effects. Saponarin improves sleep disorders .

HY-N0807

Swertiamarin	Structural Classification Monophenols other families Classification of Application Fields Phenols Zanthoxylum chiloperone var. angustifolium Metabolic Disease Plants Disease Research Fields Cancer	MMP NF-κB JAK Keap1-Nrf2
Swertiamarin is an orally active natural product with hypoglycemic, lipid-lowering, anti-rheumatic, and antioxidant activities. Swertiamarin can regulate the levels of pro-inflammatory cytokines, MMP, and NF-κB, and promote osteoblast proliferation. Swertiamarin has antioxidant and hepatoprotective effects against carbon tetrachloride induced rat liver toxicity through the Nrf2/HO-1 pathway. Swertiamarin can attenuate inflammatory mediators by regulating JAK2/STAT3 transcription factors in adjuvant induced arthritis rats. Swertiamarin can be used in the research of diabetes and arthritis .

Cat. No.	Product Name	Chemical Structure

HY-B0401S

Tolbutamide-d9
Tolbutamide-d₉ is the deuterium labeled Tolbutamide. Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic agent.

HY-B0401S1

Tolbutamide-13C
Tolbutamide- ¹³C is the ¹³C-labeled Tolbutamide. Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic agent.

HY-B0089S

Acarbose-d4
Acarbose-d₄ (BAY g 5421-d₄) is deuterium labeled Acarbose. Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC₅₀=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .

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