1. Membrane Transporter/Ion Channel
  2. GLUT
  3. DS-1150b

DS-1150b is an orally active GLUT4 activator. DS-1150b has the activity of activating GLUT4 transport and can promote the translocation of GLUT4 to the cell membrane in skeletal muscle cells. DS-1150b has shown hypoglycemic effects in the Zucker obese rat model and can be used in the study of type 2 diabetes mellitus (T2DM).

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DS-1150b Chemical Structure

DS-1150b Chemical Structure

CAS No. : 1598439-44-1

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Description

DS-1150b is an orally active GLUT4 activator. DS-1150b has the activity of activating GLUT4 transport and can promote the translocation of GLUT4 to the cell membrane in skeletal muscle cells. DS-1150b has shown hypoglycemic effects in the Zucker obese rat model and can be used in the study of type 2 diabetes mellitus (T2DM)[1].

IC50 & Target[1]

GLUT4

 

Molecular Weight

535.67

Formula

C32H41NO6

CAS No.
SMILES

CC1=C(C(O)=O)C=C(C2C(C(CC(C)(C)C3)=O)=C3OC(CC(C)(C)C4)=C2C4=O)C5=C1C=C(C)O5.CC(N)(C)C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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DS-1150b Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DS-1150b
Cat. No.:
HY-173503
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