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Results for "

hair loss

" in MedChemExpress (MCE) Product Catalog:

By Targets:	15-PGDH (1) Androgen Receptor (1) Antibiotic (3) Apoptosis (4) Bacterial (3) Biochemical Assay Reagents (1) Calcium Channel (1) Caspase (2) Collagen (1) Cytochrome P450 (2) Drug Derivative (1) Ferroptosis (1) Fungal (2) JAK (1) Melanocortin Receptor (2) Mitochondrial Metabolism (1) Platelet-activating Factor Receptor (PAFR) (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) Sirtuin (2) Sodium Channel (1) Src (1) γ-secretase (1)
By Research Areas:	Cancer (3) Infection (5) Inflammation/Immunology (6) Metabolic Disease (4) Neurological Disease (3)

By Targets:

15-PGDH (1)

Androgen Receptor (1)

Antibiotic (3)

Apoptosis (4)

Bacterial (3)

Biochemical Assay Reagents (1)

Calcium Channel (1)

Caspase (2)

Collagen (1)

Cytochrome P450 (2)

Drug Derivative (1)

Ferroptosis (1)

Fungal (2)

JAK (1)

Melanocortin Receptor (2)

Mitochondrial Metabolism (1)

Platelet-activating Factor Receptor (PAFR) (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (1)

Sirtuin (2)

Sodium Channel (1)

Src (1)

γ-secretase (1)

By Research Areas:

Cancer (3)

Infection (5)

Inflammation/Immunology (6)

Metabolic Disease (4)

Neurological Disease (3)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5253

Octapeptide-2	Apoptosis	Metabolic Disease
Octapeptide-2 is a biomimetic peptide that mimics the thymosin-β4 growth factor. Octapeptide-2 can promote hair growth, reduce cell apoptosis, and increase the proliferation of keratinocytes. Octapeptide-2 can be used in the research of hair loss and alopecia areata .

HY-P5247

Palmitoyl tetrapeptide-20 PTP20	Melanocortin Receptor Sirtuin	Metabolic Disease Inflammation/Immunology
Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide agonist of α-MSH. Palmitoyl tetrapeptide-20 promotes hair pigmentation and delays hair graying by activating the MC1-R pathway (AC₅₀: 0.16 nM), enhancing catalase activity to reduce H₂O₂ accumulation, and upregulating SIRT1 activity. Palmitoyl tetrapeptide-20 can be used in research on preventing hair loss and improving hair graying .

HY-163506

Ebselen derivative 1	Apoptosis Ferroptosis	Others
Ebselen derivative 1 (Compound 19) is a glutathione peroxidase (GPx) mimic with oral activity. Ebselen derivative 1 demonstrates significant protective effects against cisplatin (HY-17394)-induced hair cell (HC) damage both in vitro and in vivo, effectively reducing oxidative stress, apoptosis, and ferroptosis in hair cells. Ebselen derivative 1 can be utilized in the research of cisplatin (HY-17394)-induced hearing loss .

HY-116198

15-PGDH-IN-2	15-PGDH	Metabolic Disease
15-PGDH-IN-2 (Compound 2) is a 15-PGDH inhibitor with an IC₅₀ value of 0.274 nM. 15-PGDH-IN-2 can be used in research on hair loss, bone formation, gastric ulcer healing, and dermal wound healing .

HY-160692

AR antagonist 7	Androgen Receptor	Others
AR antagonist 7 (86) is an androgen receptor (AR) antagonist that can be used in the research of hair loss .

HY-P5247A

Palmitoyl tetrapeptide-20 TFA PTP20 TFA	Melanocortin Receptor Sirtuin	Metabolic Disease Inflammation/Immunology
Palmitoyl tetrapeptide-20 (PTP20) TFA is a biomimetic peptide agonist of α-MSH. Palmitoyl tetrapeptide-20 TFA promotes hair pigmentation and delays hair graying by activating the MC1-R pathway (AC₅₀: 0.16 nM), enhancing catalase activity to reduce H₂O₂ accumulation, and upregulating SIRT1 activity. Palmitoyl tetrapeptide-20 TFA can be used in research on preventing hair loss and improving hair graying .

HY-162831

MPC-IN-1	Mitochondrial Metabolism	Others
MPC-IN-1 (compound 4i) is a cyanocinnamate-based, mitochondrial pyruvate transporter (MPC) inhibitor, and is a derivative of UK-5099 (HY-15475). MPC inhibitors promote the development of hair follicle stem cells without affecting normal cells. MPC-IN-1 promotes cellular lactate production and promotes significant hair growth in mice, and has the potential to be used to inhibit hair loss .

HY-B1241A

Dihydrostreptomycin DHSM	Antibiotic Bacterial	Infection
Dihydrostreptomycin (DHSM) is an aminoglycoside antibiotic with antibacterial effect against Gram-negative bacteria. Dihydrostreptomycin exhibits ototoxicity that causes irreversible damage in inner ear hair cells, leading to hearing loss .

HY-B0612B

(S)-Lercanidipine	Calcium Channel Sodium Channel	Neurological Disease
(S)-Lercanidipine is a calcium channel blocker with antihypertensive and neuroprotective activities. (S)-Lercanidipine reduces oxidative stress and protects auditory sensory hair cells from noise-induced damage. (S)-Lercanidipine showed significant protective effects on cell viability in in vitro experiments, especially at low concentrations. (S)-Lercanidipine has been found to effectively reduce the hearing threshold of mice after noise stimulation and protect the survival of outer hair cells. The antioxidant properties of (S)-Lercanidipine are reflected in its increased expression of antioxidant enzyme genes and decreased expression of oxidative enzyme genes. (S)-Lercanidipine administration is effective in reducing noise-induced hearing loss both before and after noise exposure. (S)-Lercanidipine may alleviate noise-induced hearing loss and protect the survival of outer hair cells through its antioxidant mechanism .

HY-158012

LY3056480	γ-secretase	Others
LY3056480 is a gamma-secretase inhibitor (GSI) that inhibits Notch signaling. LY3056480 improves mild to moderate sensorineural hearing loss and is safe and tolerable. Intratympanic administration of LY3056480 induces hair cell regeneration and partial hearing recovery in mammals .

HY-B1241

Dihydrostreptomycin sulfate DHSM sulfate	Antibiotic Bacterial	Infection
Dihydrostreptomycin sulfate (DHSM sulfate) is the sulfate salt form of Dihydrostreptomycin (HY-B1241A). Dihydrostreptomycin sulfate is an aminoglycoside antibiotic with antibacterial effect against Gram-negative bacteria. Dihydrostreptomycin sulfate exhibits ototoxicity that causes irreversible damage in inner ear hair cells, leading to hearing loss .

HY-18237

KX1-004	Src	Others
KX1-004 is a potent and non-ATP competitive Src-PTK inhibitor with an IC₅₀ of 40 μM. KX1-004 protects the cochlea from hazardous noise and prevents noise-induced hearing loss (NIHL) .

HY-50856S

Deuruxolitinib CTP-543; Ruxolitinib d₈; Deuterated Ruxolitinib	JAK	Inflammation/Immunology
Deuruxolitinib, a deuterated Ruxolitinib (HY-50856), is an orally active JAK1 and JAK2 inhibitor. Deuruxolitinib demonstrates significant hair regrowth effects. Deuruxolitinib can be used for the research of alopecia areata .

HY-P0100

AHK	Reactive Oxygen Species (ROS)	Inflammation/Immunology
AHK is a bioactive peptide with antioxidant effect and has been reported used as a cosmetic ingredient .

HY-P5239

Myristoyl pentapeptide-4	Collagen	Others
Myristoyl pentapeptide-4 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .

HY-18673

PROTO-1	Biochemical Assay Reagents	Others
PROTO-1 is a hair cell protector and can be used in studies of ototoxicity-induced hair cell death .

HY-19590

Etarotene Ro 15-1570	Drug Derivative	Cancer
Etarotene (Ro 15-1570) is a derivative of Arotinoid (HY-106735). Etarotene is an orally active antitumor agent against DMBA (HY-W011845)-induced mammary tumor and causes toxic symptoms of hypervitaminosis A in rat model .

HY-B1241R

Dihydrostreptomycin sulfate (Standard) DHSM sulfate (Standard)	Reference Standards Bacterial Antibiotic	Infection
Dihydrostreptomycin (sulfate) (Standard) is the analytical standard of Dihydrostreptomycin (sulfate) (HY-B1241). This product is intended for research and analytical applications. Dihydrostreptomycin sulfate (DHSM sulfate) is the sulfate salt form of Dihydrostreptomycin (HY-B1241A). Dihydrostreptomycin sulfate is an aminoglycoside antibiotic with antibacterial effect against Gram-negative bacteria. Dihydrostreptomycin sulfate exhibits ototoxicity that causes irreversible damage in inner ear hair cells, leading to hearing loss .

HY-N2071

Cedrol 1 Publications Verification (+)-Cedrol; α-Cedrol	Cytochrome P450 Fungal Apoptosis Caspase Platelet-activating Factor Receptor (PAFR)	Infection Neurological Disease Inflammation/Immunology Cancer
Cedrol is a potent competitive inhibitor of cytochrome P-450(CYP) enzyme. Cedrol plays an anticancer role by inducing cell cycle arrest and Caspase-dependent apoptosis. Cedrol acts as a neutrophil agonist that can desensitize cells to subsequent stimulation of N-formyl peptides. Cedrol prevents neuropathic pain caused by chronic contractile injury by inhibiting oxidative stress and inflammation. In addition, Cedrol has antibacterial, hair loss prevention and anti-anxiety properties .

HY-N2071R

Cedrol (Standard)	Cytochrome P450 Fungal Apoptosis Caspase	Infection Neurological Disease Inflammation/Immunology Cancer
Cedrol (Standard) is the analytical standard of Cedrol. This product is intended for research and analytical applications. Cedrol is a potent competitive inhibitor of cytochrome P-450(CYP) enzyme. Cedrol plays an anticancer role by inducing cell cycle arrest and Caspase-dependent apoptosis. Cedrol acts as a neutrophil agonist that can desensitize cells to subsequent stimulation of N-formyl peptides. Cedrol prevents neuropathic pain caused by chronic contractile injury by inhibiting oxidative stress and inflammation. In addition, Cedrol has antibacterial, hair loss prevention and anti-anxiety properties.

Cat. No.	Product Name	Target	Research Area