Search Result
Results for "
formulation
" in MedChemExpress (MCE) Product Catalog:
68
Biochemical Assay Reagents
7
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-157049
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Biochemical Assay Reagents
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Others
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Caprylocaproyl Macrogolglycerides is a lipoidic excipient/vehicle in an oral capsule formulation. Caprylocaproyl Macrogolglycerides can enhance the absorption of small molecule compounds .
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- HY-Y0873N
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Polyethylene glycol 3000
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Biochemical Assay Reagents
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Others
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PEG3000 (Polyethylene glycol 3000) is a solvent for a large number of substances. PEG3000 can be used as a carrier material and modifying agent. PEG3000 is widely used in a variety of pharmaceutical formulations .
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- HY-Y0873B
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Polyethylene glycol 2000
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Biochemical Assay Reagents
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Others
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PEG2000 (Polyethylene glycol 2000) is a solvent for a large number of substances. PEG2000 can be used as a carrier material and modifying agent. PEG2000 is widely used in a variety of pharmaceutical formulations .
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- HY-A0104J
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Hypromellose (Type II,Viscosity:5mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s); Celacol HPM 5000 (Type II,Viscosity:5mPa.s)
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Biochemical Assay Reagents
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Others
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HPMC (Hypromellose) (Type II,Viscosity:5mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. HPMC (Type II,Viscosity:5mPa.s) is widely used in agent formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior .
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- HY-153235
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SARS-CoV
Liposome
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Infection
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COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein. COVID-19 Spike Protein undertakes the functions of virus binding with host cell receptors, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design. COVID-19 Spike Protein mRNA-LNP can be used for RNA delivery, vaccine formulation and design targeting SARS-CoV-2 .
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- HY-B1278A
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- HY-170609
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Bacterial
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Infection
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Antimicrobial agent-36 (Compound 8b) is an antimicrobial agent that significantly inhibits the level of DNA gyrase, with an IC50 value of 4.56 µM. Antimicrobial agent-36 can also be used for the preparation of nanopharmaceutical formulations, for the research and development of novel antibiotics .
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- HY-156100
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Liposome
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Others
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C12-4 is an ionizable lipid for lipid nanoparticles (LNPs) formulation.
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- HY-160705
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Liposome
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Cancer
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PNI 132, an ionizable lipid derived from the patent WO2020252589A, is useful in the formulation of lipid nanoparticles.
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- HY-142985
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Liposome
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Metabolic Disease
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Oleyl Mesylate is a derivative of Oleyl Alcohol. Oleyl Alcohol has been incorporated into various formulations for drug delivery .
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- HY-W749404
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- HY-W128313
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2,2,2-Trichloro-1-phenylethyl acetate
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Biochemical Assay Reagents
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Others
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Alpha-(trichloromethyl)benzyl acetate (2,2,2-Trichloro-1-phenylethyl acetate) can be used as a fixative in soap fragrances, especially suitable for soap and cosmetic perfume formulations, acting as a harmonizer in formulations. Alpha-(trichloromethyl)benzyl acetate is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-D1228
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Fluorescent Dye
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Others
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Pigment Red 22, a coloring agent, is used in the formulation of cleansing products, makeup, moisturizers, and night skin care products.
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- HY-B2221B
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Hydroxyethyl pectin glycosidase
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Biochemical Assay Reagents
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Others
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Hydroxyethyl cellulose is a non-ionic, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
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- HY-10980
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AN-2690
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Fungal
Antibiotic
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Infection
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Tavaborole (AN-2690) is an antifungal agent with activity against Trichophyton species, in a topical solution formulation for the potential treatment of onychomycosis.
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- HY-B1384
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Vitamin A palmitate; Retinol palmitate
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Endogenous Metabolite
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Others
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Retinyl palmitate is an ester of Retinol and is the major form of vitamin A found in the epidermis. Retinyl palmitate has been widely used in pharmaceutical and cosmetic formulations.
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- HY-145794
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Liposome
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Cancer
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ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery.
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- HY-W196368
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Reactive Oxygen Species
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Inflammation/Immunology
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Thymohydroquinone is a monoterpene molecule. Thymohydroquinone has antioxidant and anti-inflammatory properties. Thymohydroquinone can be used for pharmacokinetic studies and regulatory toxicity studies .
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- HY-16387
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VEGFR
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Others
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PF-00337210 is a potent and selective inhibitor of VEGFRs, designed for treating age-related macular degeneration via intravitreal injection. The formulation strategy focused on developing an ophthalmic solution that would precipitate upon injection into the vitreous, ensuring sustained drug delivery. Challenges included maintaining low dosing volumes, selecting safe excipients for intravitreal use, and addressing the drug's unique physicochemical properties. The final formulation, an isotonic solution in a citrate-buffered vehicle with NaCl, demonstrated stability, potency, and recovery through intravitreal dosing syringes. It formed a depot upon injection into vitreous humor, representing a novel nonpolymeric in situ-forming depot formulation for intravitreal drug delivery .
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- HY-Y0873A
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PEG400
Maximum Cited Publications
20 Publications Verification
Polyethylene glycol 400
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Biochemical Assay Reagents
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Others
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PEG400 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances. PEG400 is widely used in a variety of pharmaceutical formulations.
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- HY-N12028
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Others
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Others
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Acacetin 7-O-glucuronide is a glucuronide isolated from the methanolic leaf extract of Acacetin. Acacetin 7-O-glucuronide has potential applications in the development of nutraceuticals and pharmaceutical formulations .
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- HY-157374
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Biochemical Assay Reagents
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Others
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Beef Heart Infusion is a non-selective microbial culture medium formulation. Beef Heart Infusion provides nutrients for microbial growth. Beef Heart Infusion can be used for the culture, transplantation and rejuvenation of microorganisms.
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- HY-10980R
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AN-2690 (Standard)
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Fungal
Antibiotic
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Infection
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Tavaborole (Standard) is the analytical standard of Tavaborole. This product is intended for research and analytical applications. Tavaborole (AN-2690) is an antifungal agent with activity against Trichophyton species, in a topical solution formulation for the potential treatment of onychomycosis.
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- HY-B1278AR
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Vitamin E acetate (Standard)
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Endogenous Metabolite
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Inflammation/Immunology
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DL-α-Tocopherol acetate (Standard) is the analytical standard of DL-α-Tocopherol acetate. This product is intended for research and analytical applications. DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition.
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- HY-W127434A
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(12R)-Octadecane-1,12-diol
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Biochemical Assay Reagents
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Others
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(12R)-1,12-Octadecanediol ((12R)-Octadecane-1,12-diol) is a compound characterized by a linear chain of 18 carbon atoms with two hydroxyl groups (C18H38O2). This colorless substance has unique properties owing to the presence of two hydroxyl groups in its molecular structure.
Whether derived from natural sources or synthesized chemically, 12-Octadecanediol finds applications in various industries. It is often utilized in the formulation of cosmetics, personal care products, and pharmaceuticals due to its emollient properties, enhancing moisturization and conditioning effects in different formulations. The compound's distinctive structure may make it suitable for specific uses in research or industrial processes.
In industrial contexts, 12-Octadecanediol serves as a valuable chemical intermediate for synthesizing other compounds. Its specialized structure and adaptability in formulations make it a significant component across diverse industries, contributing to the development of products for various purposes.
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- HY-106673
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Hydrocortisone probutate; HBP
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Glucocorticoid Receptor
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Inflammation/Immunology
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Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation .
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- HY-143209B
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Liposome
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Others
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DSPE-PEG3400 is a phospholipids-polymer conjugate that can be used in drug delivery applications. DSPE-PEG3400 is a material for the formulation of nanocarriers for achieving prolonged blood circulation time, improved stability and enhanced encapsulation efficiency .
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- HY-118896
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AKD-2023; DPX-3792
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Parasite
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Infection
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Acequinocyl (CRM) is a certified reference material categorized as a naphthoquinone acaricide.1 Acequinocyl has been found in Cannabis. Formulations containing acequinocyl have been used to control mite populations in agriculture. This product is intended for research and forensic applications.
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- HY-W441001
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Biochemical Assay Reagents
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Others
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DSPE-Fluorescein is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Fluoresceincan be used in drug delivery research .
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- HY-118547
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2-Benzyl-4-chlorophenol
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Bacterial
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Infection
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Clorofene (2-Benzyl-4-chlorophenol) is an aryl halide fungicide widely used in hospitals and homes as a broad-spectrum fungicide in general cleaning and disinfection disinfectant solutions and in soap formulations. Clorofene has antibacterial and carcinogenic activity .
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- HY-114335
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NF-κB
Fungal
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Infection
Inflammation/Immunology
Cancer
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Triphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica . Triphala inhibits NF-κB activation. Triphala exerts antifungal action . Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities.
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- HY-167932
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RU486 methochloride; RU 38486 methochloride
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Progesterone Receptor
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Endocrinology
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Mifepristone (RU486) methochloride is a glucocorticoid antagonist that blocks peripheral glucocorticoid and progesterone receptors. Mifepristone methochloride has been shown to have minimal effects on intraocular pressure in treated rabbits. Mifepristone methochloride was developed as a water-soluble formulation to enhance ocular penetration of the drug.
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- HY-120435
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Bacterial
Fungal
Influenza Virus
Antibiotic
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Infection
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Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin shows activity against bacteria, fungi and some viruses. Tyrothricin containing formulations are used in sore throat agents and in agents for the healing of infected superficial and small-area wounds .
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- HY-W127452
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Biochemical Assay Reagents
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Others
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Undecylenate SodiumIt is an organic compound belonging to the class of carboxylates. It is formed by the reaction of undecylenic acid and sodium hydroxide. Undecylenate SodiumIt has a variety of applications in the cosmetic and personal care industries, especially as an antifungal agent in products such as face creams, lotions and shampoos. In addition, it can be used as a preservative in various formulations.
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- HY-166560
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Biochemical Assay Reagents
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Others
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DSPE-Fluor 488 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Fluor 488can be used in drug delivery research .
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- HY-166849
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Biochemical Assay Reagents
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Others
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B22&" is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B22&"can be used in drug delivery research ."
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- HY-143692
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- HY-N0455D
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(S)-(+)-Arginine butanoate
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Biochemical Assay Reagents
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Others
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L-Arginine butanoate ((S)-(+)-Arginine butanoate) is a compound consisting of L-Arginine and butanoate. L-Arginine is one of the essential nutrients in the human body and participates in various biochemical processes. Butanoate is a short-chain fatty acid commonly used as a food additive and solvent in pharmaceutical formulations .
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- HY-W440987
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Biochemical Assay Reagents
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Others
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DOPE-mPEG (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. DOPE-mPEG (MW 1000) can be used in drug delivery research .
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- HY-W800741
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Biochemical Assay Reagents
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Others
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Undecyl 8-bromooctanoate is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. Undecyl 8-bromooctanoate can be used in drug delivery research .
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- HY-W016445
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1-Amino-1-deoxy-D-glucitol, 98%
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Biochemical Assay Reagents
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Others
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D-Glucamine, 98% (1-Amino-1-deoxy-D-glucitol, 98%) is an amino-sugar derivative and can be used as an excipient in pharmaceutical formulations. D-Glucamine, 98% can also be used as a substrate for sugar transporter pathway assay studies .
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- HY-Y0921S1
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1,2-(RS)-Propanediol-d2; 1,2-Propylene glycol-d2; Propylene glycol-d2
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Endogenous Metabolite
Isotope-Labeled Compounds
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Neurological Disease
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(±)-1,2-Propanediol-d2 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents .
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- HY-Y0921S
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1,2-(RS)-Propanediol-d8; 1,2-Propylene glycol-d8; Propylene glycol-d8
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Endogenous Metabolite
Isotope-Labeled Compounds
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Neurological Disease
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(±)-1,2-Propanediol-d8 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents .
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- HY-Y0921S2
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1,2-(RS)-Propanediol-d6; 1,2-Propylene glycol-d6; Propylene glycol-d6
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Isotope-Labeled Compounds
Endogenous Metabolite
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Neurological Disease
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(±)-1,2-Propanediol-d6 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents .
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- HY-B1278AS
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Vitamin E acetate-13C4,d6
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Isotope-Labeled Compounds
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Inflammation/Immunology
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DL-α-Tocopherol acetate- 13C4,d6 is the deuterium and 13C labeled DL-α-Tocopherol acetate[1]. DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition[2][3].
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- HY-W440989
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Biochemical Assay Reagents
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Others
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DOPE-mPEG (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-mPEG (MW 5000)can be used in drug delivery research .
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- HY-166606
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Biochemical Assay Reagents
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Others
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DSPE-polysarcosine66 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-polysarcosine66can be used in drug delivery research .
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- HY-19873
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Photosensitizer
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Cancer
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SL-052 is a hypocrellin-based photosensitizer that has recently shown promising results in clinical and preclinical testing for cancer photodynamic therapy (PDT). SL-052 is encapsulated in biodegradable polylactic-co-glycolic acid (PLGA) polymer nanoparticles optimized using single emulsion solvent evaporation technology. The SL-052-PLGA nanoparticles were more effective in PDT treatment of subcutaneous SCCVII squamous cell carcinoma compared to polyvinylpyrrolidone (PVP)-based and standard liposomal SL-052 formulations. A longer time interval between drug injection and tumor illumination can improve tumor cure rates, and SL-052-PLGA nanoparticles showed the best therapeutic effect among all SL-052 formulations.
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- HY-166680
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Biochemical Assay Reagents
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Others
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DOPE-PEG-FITC (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-FITC (MW 5000)can be used in drug delivery research .
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- HY-166648
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Biochemical Assay Reagents
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Others
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DSPE-PEG-Maleimide (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-PEG-Maleimide (MW 2000)can be used in drug delivery research .
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- HY-W440828
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Biochemical Assay Reagents
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Others
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DOPE-PEG-COOH (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-COOH (MW 3400)can be used in drug delivery research .
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- HY-W440997
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Mal (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Mal (MW 5000)can be used in drug delivery research .
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- HY-W250302
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Biochemical Assay Reagents
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Others
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Methylbenzethonium chloride is a quaternary ammonium compound commonly used as a preservative and disinfectant in a variety of personal care and healthcare products. Methylbenzethonium chloride has several properties that make it suitable for these applications, including its broad-spectrum antibacterial activity against bacteria, viruses and fungi. In addition, it is used as a preservative in cosmetic and pharmaceutical formulations to prevent the growth of microorganisms.
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- HY-W591450
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Azide (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Azide (MW 3400)can be used in drug delivery research .
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- HY-W440993
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Amine (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 5000)can be used in drug delivery research .
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- HY-W440996
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Mal (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Mal (MW 3400)can be used in drug delivery research .
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- HY-W591448
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Azide (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Azide (MW 1000)can be used in drug delivery research .
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- HY-166846
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Biochemical Assay Reagents
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Others
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DOPE-PEG-FITC (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-FITC (MW 2000)can be used in drug delivery research .
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- HY-166644
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Biochemical Assay Reagents
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Others
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DPPE-PEG-amine (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DPPE-PEG-amine (MW 2000)can be used in drug delivery research .
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- HY-W591451
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Azide (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Azide (MW 5000)can be used in drug delivery research .
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- HY-W440992
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Amine (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 3400)can be used in drug delivery research .
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- HY-W440826
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Biochemical Assay Reagents
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Others
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DOPE-PEG-COOH (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-COOH (MW 1000)can be used in drug delivery research .
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- HY-W440829
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Biochemical Assay Reagents
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Others
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DOPE-PEG-COOH (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-COOH (MW 5000)can be used in drug delivery research .
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- HY-W440994
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Mal (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Mal (MW 1000)can be used in drug delivery research .
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- HY-W127445
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Docosanamide
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Biochemical Assay Reagents
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Others
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Behenamide is a fatty acid derived from plants such as rapeseed oil and can be synthesized by a variety of processes. Behenamide has unique properties that make it useful as a slip agent, A lubricant and release agent, it is also used in personal care products, including cosmetics and hair care, as a thickener and emollient because of its ability to improve the consistency and texture of formulations.
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- HY-W127627
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Biochemical Assay Reagents
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Others
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Tween 85 is a nonionic surfactant belonging to the class of ethoxylated sorbitan esters. It is used as an emulsifier and solubilizer in various industries such as pharmaceutical, cosmetic and food. Because of its ability to blend oily and water-based ingredients, Tween 85 is often used in the formulation of creams, lotions and ointments. In addition, it is used as a dispersant for pigments in the production of paints and coatings.
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- HY-166857
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Biochemical Assay Reagents
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Others
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DMPE-PEG-amine (TFA) (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DMPE-PEG-amine (TFA) (MW 2000)can be used in drug delivery research .
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- HY-166654
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Biochemical Assay Reagents
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Others
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DSPE-Amide-PEG-Rhodamine (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Amide-PEG-Rhodamine (MW 2000)can be used in drug delivery research .
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- HY-W590667
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Biochemical Assay Reagents
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Others
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C2 Ceramide-1-phosphate is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. C2 Ceramide-1-phosphatecan be used in drug delivery research .
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-
- HY-106673R
-
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Glucocorticoid Receptor
|
Inflammation/Immunology
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|
Hydrocortisone buteprate (Standard) is the analytical standard of Hydrocortisone buteprate. This product is intended for research and analytical applications. Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation .
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-
- HY-166833
-
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Rhodamine B (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Rhodamine B (MW 5000)can be used in drug delivery research .
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-
- HY-166651
-
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Biochemical Assay Reagents
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Others
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DSPE-Hyd-PEG-Mal (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Hyd-PEG-Mal (MW 2000)can be used in drug delivery research .
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-
- HY-118896R
-
|
|
Parasite
|
Infection
|
|
Acequinocyl (Standard) is the analytical standard of Acequinocyl. This product is intended for research and analytical applications. Acequinocyl (CRM) is a certified reference material categorized as a naphthoquinone acaricide.1 Acequinocyl has been found in Cannabis. Formulations containing acequinocyl have been used to control mite populations in agriculture. This product is intended for research and forensic applications.
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-
- HY-166852
-
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Cy5 (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Cy5 (MW 2000)can be used in drug delivery research .
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- HY-148124
-
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Drug Isomer
Parasite
Antibiotic
Bacterial
MMP
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Others
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6-Epi-doxycycline is the C-6 epimer of Doxycycline (HY-N0565), formed as a degradation impurity through epimerization of Doxycycline under abnormal conditions (e.g., high temperature, pH changes, or humidity). 6-Epi-doxycycline is commonly used for the detection and analysis of impurity levels in pharmaceutical formulations .
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-
- HY-W010900
-
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Biochemical Assay Reagents
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Others
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Tetrahexylammonium bromide is a compound that belongs to the class of quaternary ammonium compounds. It is a salt with cationic properties and thus useful in various industrial and biomedical applications. Tetrahexylammonium bromide is commonly used as a phase transfer catalyst to facilitate the movement of reactants between immiscible phases in various organic synthesis reactions. It is also used as a surfactant and emulsifier in the formulation of detergents, personal care products and pharmaceuticals.
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- HY-B0661C
-
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YM12617 hydrochloride; LY253351 hydrochloride
|
Adrenergic Receptor
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Endocrinology
|
|
Tamsolusin (YM12617) hydrochloride is a highly selective alpha-1A adrenergic receptor antagonist used in the treatment of benign prostatic hypertrophy, demonstrating effective biological activity in alleviating associated symptoms. Tamsolusin hydrochloride can also be quantified using a validated spectrofluorimetric method, showcasing its potential for routine quality control analysis in pharmaceutical formulations.
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-
- HY-A0087R
-
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Biochemical Assay Reagents
Reference Standards
PPAR
Estrogen Receptor/ERR
Cytochrome P450
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Others
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|
Octocrylene (Standard) is the analytical standard of Octocrylene. This product is intended for research and analytical applications. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation .
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-
- HY-166848
-
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Cy5.5 (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Cy5.5 (MW 2000)can be used in drug delivery research .
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-
- HY-112768
-
|
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Liposome
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Others
|
|
PEG2000-DMPE can be used to synthsis a LNP. PEG2000-DMPE enhances the entrapment efficiency depending on the increasing portion in the liposome. The optimal formulation for animal study is that DMPC/PEG2000-DMPE/CH=50/5/45 at the weight ratio of drug/lipid=1/20 .
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-
- HY-100375
-
|
ALKS 8700; BIIB098
|
Keap1-Nrf2
|
Inflammation/Immunology
|
|
Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity .
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-
- HY-166850
-
|
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Biochemical Assay Reagents
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Others
|
|
DOPE-PEG-Cy5.5 (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Cy5.5 (MW 5000)can be used in drug delivery research .
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-
- HY-129923
-
|
|
Cytochrome P450
|
Neurological Disease
|
|
(R)-Omeprazole sodium is a gastric acid resistant compound with activity to inhibit gastric acid secretion. (R)-Omeprazole sodium is metabolized in vivo, and its metabolism is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. (R)-Omeprazole sodium exhibits reversible direct and metabolism-dependent inhibition of CYP2C19 .
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-
- HY-145530
-
-
- HY-158569
-
|
|
Endogenous Metabolite
|
Others
|
|
SAR114137 is a highly effective drug with potent biological activity. SAR114137 exhibits altered amorphous content characteristics during physical processing of the crystalline active pharmaceutical ingredient. The amorphous API content of SAR114137 is significantly reduced when processed by different jet grinding techniques. SAR114137 exhibits good chemical stability in pharmaceutical formulations .
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-
- HY-W012412
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Tetrapropylammonium chloride is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and is used in various industrial and biomedical applications. Tetrapropylammonium chloride is commonly used as a phase transfer catalyst to facilitate the movement of reactants between immiscible phases in organic synthesis reactions. It is also used as a surfactant in the formulation of personal care products, detergents, textiles and pharmaceuticals. Additionally, it is used in the production of certain types of polymers and resins.
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-
- HY-W013076
-
|
tetra(decyl)ammonium bromide
|
Biochemical Assay Reagents
|
Others
|
|
Tetrakis(decyl)ammonium bromide is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and is used in various industrial and biomedical applications. Tetrakis(decyl)ammonium bromide is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, cleansers and pharmaceutical formulations. It is also used as a phase transfer catalyst in organic synthesis reactions, facilitating the movement of reactants between immiscible phases.
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-
- HY-W738314
-
|
|
Biochemical Assay Reagents
|
|
|
Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is a chemically modified cyclodextrin with good cosolvent activity. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is widely used in compound formulations to improve the solubility and bioavailability of compounds. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate helps improve the release characteristics of compounds.
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-
- HY-W250302R
-
|
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Biochemical Assay Reagents
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Others
|
|
Methylbenzethonium (chloride) (Standard) is the analytical standard of Methylbenzethonium (chloride). This product is intended for research and analytical applications. Methylbenzethonium chloride is a quaternary ammonium compound commonly used as a preservative and disinfectant in a variety of personal care and healthcare products. Methylbenzethonium chloride has several properties that make it suitable for these applications, including its broad-spectrum antibacterial activity against bacteria, viruses and fungi. In addition, it is used as a preservative in cosmetic and pharmaceutical formulations to prevent the growth of microorganisms.
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-
- HY-W101253
-
|
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Biochemical Assay Reagents
|
Others
|
|
Tetraethylammonium (iodide) is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is commonly used as a phase-transfer catalyst in organic synthesis because it facilitates the transfer of reactants between immiscible phases. It can also be used as an electrolyte in electrochemical devices and as a surfactant in detergent formulations. Its unique chemical properties make it an important ingredient in a variety of industrial applications, including pharmaceuticals, agrochemicals, and materials science.
|
-
- HY-159176
-
|
|
Cytochrome P450
|
Cancer
|
|
Antitumor agent-183 (compound 3f) has antitumor activity with metabolic stability. Antitumor agent-183 inhibits cancer cell growth, with IC50s less than 5 nM for A549, HCT116, and HS578T cells. The albumin-bound nanoparticle formulation of Antitumor agent-183 has prolonged retention in the tumor tissues .
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-
- HY-15321A
-
|
MK-0663 hydrochloride; L-791456 hydrochloride
|
COX
|
Inflammation/Immunology
|
|
Etoricoxib hydrochloride (MK-0663 hydrochloride) is a synthetic nonsteroidal anti-inflammatory drug with cyclooxygenase-2 inhibitory activity. Etoricoxib hydrochloride can inhibit the conversion of arachidonic acid to prostaglandins, thereby reducing inflammation and pain. Etoricoxib hydrochloride is used to inhibit osteoarthritis and has anti-inflammatory and bone remodeling effects. The formulation of etoricoxib hydrochloride is prepared by emulsion solvent evaporation technology and exhibits good cell compatibility and enhanced alkaline phosphatase activity .
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-
- HY-134120
-
|
DL-2-Hydroxystearic acid
|
Biochemical Assay Reagents
|
Others
|
|
2-Hydroxystearic acid is an alpha-hydroxy fatty acid commonly used in a variety of personal care products, especially cosmetic and skin care formulations. 2-Hydroxystearic acid has unique chemical properties that make it an effective emulsifier and stabilizer, improving the texture and shelf life of cosmetic products. It also has a potential physiological role in improving skin hydration and elasticity, although its biological function is not fully understood.
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-
- HY-115415
-
|
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Liposome
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Others
|
|
1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt has unique chemical properties that make it an effective tool for encapsulating drugs and delivering them to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
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-
- HY-W127785
-
|
N,N-Dimethyldodecylamine N-oxide; Dodecyldimethylamine oxide
|
Biochemical Assay Reagents
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Others
|
|
N-ethyl-N-oxido-dodecan-1-amine is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power.
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-
- HY-166992
-
|
|
Biochemical Assay Reagents
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Others
|
|
1,2-Dioleoyl-sn-glycero-3-PA (ammonium) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. 1,2-Dioleoyl-sn-glycero-3-PA (ammonium)can be used in drug delivery research .
|
-
- HY-W101256
-
|
Triethylmethylammonium tetrafluoroborate
|
Biochemical Assay Reagents
|
Others
|
|
N,N-Diethyl-N-methylethanaminium tetrafluoroborate is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is commonly used as a phase transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. Additionally, it is used as an electrolyte in electrochemical devices and as a surfactant in detergent formulations. Its unique chemical properties make it an important ingredient in a variety of industrial applications, including pharmaceuticals, agrochemicals, and materials science.
|
-
- HY-W012167
-
|
|
Biochemical Assay Reagents
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Others
|
|
N,N,N-Trimethyldecan-1-aminium chloride is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and thus useful in various industrial and biomedical applications. Decyltrimethylammonium chloride is commonly used as a surfactant, emulsifier and disinfectant in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a phase transfer catalyst in organic synthesis reactions, which involves facilitating the movement of reactants between immiscible phases.
|
-
- HY-143702
-
|
NBD-DOTAP
|
Fluorescent Dye
Liposome
|
Inflammation/Immunology
Cancer
|
|
Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research .
|
-
- HY-115369
-
|
|
Biochemical Assay Reagents
|
Others
|
|
cis-13,16,19-Docosatrienoic acid methyl ester is an ester form of docosatrienoic acid, a rare omega-3 fatty acid not found in the normal phospholipid polyunsaturated fatty acid pool Easily detectable, it inhibits the binding of [3H]-LTB4 to porcine neutrophils at a concentration of 5 μM. Methyl docosatrienoate is more fat-soluble than the free acid and may be more desirable than the free acid in some formulations.
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-
- HY-115340
-
|
|
Biochemical Assay Reagents
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Others
|
|
Decanoic acid sodium, also known as Decanoic acid sodium, is a salt of the fatty acid capric acid. It is easily soluble in water and has a slightly soapy smell. Decanoic acid sodium acts as a penetration enhancer, which means it increases the absorption and bioavailability of drugs across biological membranes, including the intestinal epithelium and the blood-brain barrier. This property makes it useful in pharmaceutical formulations to improve drug delivery and effectiveness. Furthermore, Decanoic acid sodium has potential applications in food preservatives and cosmetics due to its antibacterial properties.
|
-
- HY-B0216S
-
|
17α-Ethynylestradiol-d4; Ethynylestradiol-d4
|
Estrogen Receptor/ERR
Endogenous Metabolite
|
Endocrinology
Cancer
|
|
Ethynyl Estradiol-d4 is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W007174A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,4-Anhydro-D-xylitol is a compound belonging to the class of sugar alcohols. It is derived from xylitol, a natural sweetener found in many fruits and vegetables. 1,4-Anhydro-D-xylitol is commonly used as a low-calorie sweetener and excipient in the food and pharmaceutical industries, and as a filler or binder in pharmaceutical formulations. It has also been investigated for its potential use in the development of biodegradable plastics and other sustainable materials.
|
-
- HY-125619
-
|
|
Liposome
|
Others
|
|
1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
|
-
- HY-W008974
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-(Dimethyl(octadecyl)ammonio)propane-1-sulfonate is a class of quaternary ammonium compounds. It is a surfactant and cationic detergent with amphiphilic properties and therefore useful in various industrial and biomedical applications. 3-(Dimethyl(octadecyl)ammonium)propane-1-sulfonate is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a reagent in analytical chemistry, especially in the analysis of proteins and DNA.
|
-
- HY-129923R
-
|
|
HBV
|
Neurological Disease
|
|
(R)-Omeprazole (sodium) (Standard) is the analytical standard of (R)-Omeprazole (sodium). This product is intended for research and analytical applications. (R)-Omeprazole sodium is a gastric acid resistant compound with activity to inhibit gastric acid secretion. (R)-Omeprazole sodium is metabolized in vivo, and its metabolism is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. (R)-Omeprazole sodium exhibits reversible direct and metabolism-dependent inhibition of CYP2C19 .
|
-
- HY-139554
-
|
KBP-7072
|
Antibiotic
Bacterial
|
Infection
|
|
Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
|
-
- HY-134338R
-
|
|
Parasite
|
Others
|
|
(R)-Omeprazole (sodium) (Standard) is the analytical standard of (R)-Omeprazole (sodium). This product is intended for research and analytical applications. (R)-Omeprazole sodium is a gastric acid resistant compound with activity to inhibit gastric acid secretion. (R)-Omeprazole sodium is metabolized in vivo, and its metabolism is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. (R)-Omeprazole sodium exhibits reversible direct and metabolism-dependent inhibition of CYP2C19 .
|
-
- HY-N0711
-
|
Cymophenol
|
Notch
Apoptosis
Fungal
Endogenous Metabolite
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
|
Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .
|
-
- HY-B0380B
-
|
GIC-1001
|
Biochemical Assay Reagents
|
Others
|
|
Trimebutine 3-TCBS (GIC-1001) is an innovative formulation designed to release hydrogen sulfide (H2S) in vivo. This compound combines trimebutine with an H2S-releasing antagonist (phenyl 3-thiocarbamate) and exhibits enhanced anti-nociceptive effects in a mouse colonic distension model, superior to conventional trimebutine. GIC-1001 can reduce visceral pain and discomfort associated with lumen distension in a dose-dependent manner, showing potential superiority .
|
-
- HY-112766
-
|
|
Liposome
|
Others
|
|
DPyPE is a neutral phosphatidylethanolamine lipid composed of a polyisoprene alkyl chain with two pyridine-containing phosphine ligands. DPyPE is mainly used in liposome formulations and to enhance the efficiency of gene delivery in vitro and in vivo. For example, DPyPE can be mixed with cationic lipids such as VC1052 (HY-156616) (in a 1:1 ratio) to form the vaccine adjuvant Vaxfectin (HY-142998). DPyPE assists VC1052 in binding to negatively charged pDNA to form a uniform liposome complex by regulating the fluidity and stability of the liposome membrane .
|
-
- HY-137499
-
|
|
Liposome
Endogenous Metabolite
|
Neurological Disease
|
|
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
|
-
- HY-165604
-
|
|
Liposome
|
Others
|
C14-490, an ionizable cationic lipid (pKa = 5.94), is used for the synthesis of lipid nanoparticles (LNPs). C14-490 LNPs is used as the basis for subsequent study of in utero gene editing in HSCs. C14-490 LNPs are used to encapsulate SpCas9 mRNA and TTR sgRNA using optimized B5 formulation parameters and surface conjugation to CD45 antibody F(ab’)2 fragments-Systematically optimized Targeted Editing Machinery LNPs (STEM LNPs) .
|
-
- HY-W250168
-
|
Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10
|
Biochemical Assay Reagents
|
Others
|
|
Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.
|
-
- HY-P99974
-
|
Nanoparticle albumin-bound Paclitaxel; Nanoparticle albumin-bound ABI-007
|
Microtubule/Tubulin
Apoptosis
Autophagy
|
Cancer
|
|
Nab-Paclitaxel is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel, in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel was associated with higher response rates and better tolerability, with favorable pharmacokinetic properties . (The product size below only indicate the effective content of Paclitaxel. The actual albumin quality depends on the batch. The ratio of each component in this product is Paclitaxel: albumin = 1:7-1:11).
|
-
- HY-167680
-
|
GSK823093
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings .
|
-
- HY-W754025
-
|
|
VD/VDR
|
Others
|
|
Pre-vitamin D3 decanoate is a derivative of vitamin D3 that can be converted into the active form of vitamin D in the body. Pre-vitamin D3 decanoate is first converted to 25-hydroxyvitamin D3 in the liver and then further converted to 1,25-dihydroxyvitamin D3 in the kidneys. During preparation, vitamin D3 may react with the triglycerides in the formulation to form ester compounds, and this esterification affects the stability and bioavailability of vitamin D3. Pre-vitamin D3 decanoate can be used in the study of certain diseases associated with vitamin D, such as osteoporosis, autoimmune diseases, and certain cancers .
|
-
- HY-W414697
-
|
D-Ribo-phytosphingosine (C17 base)
|
Bacterial
|
Others
|
|
4-Hydroxysphinganine C17 base (D-Ribo-phytosphingosine C17 base), also known as D-ribo-phytosphingosine or PHS, is a crucial compound present in the membranes of fungi, plants, bacteria, marine organisms, and mammalian tissues. It plays a vital role in preserving the structural integrity of membranes, regulating cellular growth, and mediating the heat stress response in yeast. Additionally, PHS serves as a precursor for the synthesis of important lipid mediators such as PHS 1-phosphate, inositol phosphorylceramide, and KRN7000 (the α-anomer of galactosylceramide). Furthermore, this phospholipid promotes keratinocyte differentiation, making it a valuable active ingredient in cosmetic formulations.
|
-
- HY-N0711R
-
|
|
Notch
Apoptosis
Fungal
Endogenous Metabolite
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
|
Carvacrol (Standard) is the analytical standard of Carvacrol. This product is intended for research and analytical applications. Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .
|
-
- HY-134809A
-
|
CADA hydrochloride
|
HIV
|
Infection
|
|
Cyclotriazadisulfonamide (CADA) hydrochloride is a specific CD4-targeted HIV entry inhibitor with activity against HIV-1 replication. Cyclotriazadisulfonamide hydrochloride can specifically downregulate the expression of CD4 receptors on the cell surface, effectively inhibiting HIV transmission. Cyclotriazadisulfonamide hydrochloride can inhibit HIV-1(NL4.3) and SIV(mac251), and has a synergistic effect when used in combination with cellulose acetate (CAP). Cyclotriazadisulfonamide hydrochloride can also be used as a microbial gel formulation to maintain CD4 downregulation and antiviral activity, and is a broad-spectrum anti-HIV agent.
|
-
- HY-W127785R
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-ethyl-N-oxido-dodecan-1-amine (Standard) is the analytical standard of N-ethyl-N-oxido-dodecan-1-amine. This product is intended for research and analytical applications. N-ethyl-N-oxido-dodecan-1-amine is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power.
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- HY-134098
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Adipic acid diisopropyl ester
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TRP Channel
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Others
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Diisopropyl adipate is an alternative plasticizer and a TRPA1 activator. Diisopropyl adipate activates TRPA1 and enhances FITC-induced contact hypersensitivity (CHS).Diisopropyl adipate also serves as an ingredient in cosmetics and drug formulations topically applied to the skin. Diisopropyl adipate can be used as an excipient, such as emollients, plasticizers. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-N3387
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Apoptosis
NF-κB
Akt
MMP
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Inflammation/Immunology
Cancer
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Licoricidin (LCD) is isolated from Glycyrrhiza uralensis Fisch, possesses anti-cancer activities. Licoricidin (LCD) inhibit SW480 cells (IC50=7.2 μM) by inducing cycle arrest, apoptosis and autophagy, and is a potential chemopreventive or chemotherapeutic agent against colorectal cancer . Licoricidin (LCD) inhibits Lung Metastasis by inhibition of tumor angiogenesis and lymphangiogenesis as well as changes in the local microenvironment of tumor tissues the anticarcinogenic effect . Licoricidin enhanced gemcitabine-induced cytotoxicity in Osteosarcoma (OS) cells by inactivation of the Akt and NF-κB pathways in vitro and in vivo . Licoricidin blocks UVA-induced photoaging via ROS scavenging, limits the activity of MMP-1, it can be considered as an active ingredient in new topically applied anti-ageing formulations .
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- HY-141582
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N-Stearoyl phytosphingosine
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Biochemical Assay Reagents
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Others
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C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. Cer(t18:0/18:0) consists of a phytosphingosine backbone amine linked to a C18 fatty acid chain. Cer(t18:0/18:0) has the function of regulating apoptosis, cell differentiation, proliferation of smooth muscle cells and inhibition of mitochondrial respiratory chain. It also suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue. Formulations containing cer(t18:0/18:0) have been used as skin protectants in cosmetics as they reduce water loss and prevent epidermal dehydration and irritation.
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- HY-W012952R
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Biochemical Assay Reagents
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Others
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(2E,4E)-Hepta-2,4-dienal (Standard) is the analytical standard of (2E,4E)-Hepta-2,4-dienal. This product is intended for research and analytical applications. (2E,4E)-Hepta-2,4-dienal is a naturally occurring organic compound that belongs to the group of aldehydes. It is an unsaturated aldehyde with two conjugated double bonds, giving it unique chemical and physical properties. (2E,4E)-Hepta-2,4-dienal is commonly found in various plant sources, especially in spices such as parsley and coriander. It is used as a flavoring agent and food additive in the formulation of various foods such as baked goods, snacks and beverages. It is also used in the fragrance industry, especially in the production of perfume and cologne.
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- HY-141582S
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N-Stearoyl phytosphingosine-d3
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Isotope-Labeled Compounds
Biochemical Assay Reagents
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Others
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Ceramide 3-d3 (N-Stearoyl phytosphingosine-d3) is deuterium labeled Ceramide 3. C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. Cer(t18:0/18:0) consists of a phytosphingosine backbone amine linked to a C18 fatty acid chain. Cer(t18:0/18:0) has the function of regulating apoptosis, cell differentiation, proliferation of smooth muscle cells and inhibition of mitochondrial respiratory chain. It also suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue. Formulations containing cer(t18:0/18:0) have been used as skin protectants in cosmetics as they reduce water loss and prevent epidermal dehydration and irritation .
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-
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HY-L048
-
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442 compounds
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The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds. Additionally, identifying novel drug targets is challenging because there are many similarities between fungal and human cells. The most common antifungal targets include fungal RNA synthesis and cell wall and membrane components, though new antifungal targets are being investigated. Nonetheless, fungi have developed resistance mechanisms, such as overexpression of efflux pump proteins, overexpression and changes in drug targets and biofilm formation, emphasizing the importance of discovering new antifungal drugs and therapies. Due to the limited antifungal arsenal, researchers have sought to improve treatment via different approaches, such as the combination of antifungal drugs, development of new formulations for antifungal agents and modifications to the chemical structures of traditional antifungals, etc.
MCE offers a unique collection of 442 compounds with validated antifungal activities. MCE antifungal compound library is an effective tool for drug repurposing screening, combination screening and biological investigation.
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| Cat. No. |
Product Name |
Type |
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- HY-D1228
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Dyes
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Pigment Red 22, a coloring agent, is used in the formulation of cleansing products, makeup, moisturizers, and night skin care products.
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| Cat. No. |
Product Name |
Type |
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- HY-Y0873N
-
|
Polyethylene glycol 3000
|
Co-solvents
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|
PEG3000 (Polyethylene glycol 3000) is a solvent for a large number of substances. PEG3000 can be used as a carrier material and modifying agent. PEG3000 is widely used in a variety of pharmaceutical formulations .
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- HY-153235
-
|
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Drug Delivery
|
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COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein. COVID-19 Spike Protein undertakes the functions of virus binding with host cell receptors, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design. COVID-19 Spike Protein mRNA-LNP can be used for RNA delivery, vaccine formulation and design targeting SARS-CoV-2 .
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- HY-145794
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|
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Drug Delivery
|
|
ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery.
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-
- HY-Y0873A
-
PEG400
Maximum Cited Publications
20 Publications Verification
Polyethylene glycol 400
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Co-solvents
|
|
PEG400 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances. PEG400 is widely used in a variety of pharmaceutical formulations.
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-
- HY-157374
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Microbial Culture
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Beef Heart Infusion is a non-selective microbial culture medium formulation. Beef Heart Infusion provides nutrients for microbial growth. Beef Heart Infusion can be used for the culture, transplantation and rejuvenation of microorganisms.
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-
- HY-W127452
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|
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Drug Delivery
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Undecylenate SodiumIt is an organic compound belonging to the class of carboxylates. It is formed by the reaction of undecylenic acid and sodium hydroxide. Undecylenate SodiumIt has a variety of applications in the cosmetic and personal care industries, especially as an antifungal agent in products such as face creams, lotions and shampoos. In addition, it can be used as a preservative in various formulations.
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-
- HY-142985
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|
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Drug Delivery
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|
Oleyl Mesylate is a derivative of Oleyl Alcohol. Oleyl Alcohol has been incorporated into various formulations for drug delivery .
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-
- HY-W128313
-
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2,2,2-Trichloro-1-phenylethyl acetate
|
Biochemical Assay Reagents
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|
Alpha-(trichloromethyl)benzyl acetate (2,2,2-Trichloro-1-phenylethyl acetate) can be used as a fixative in soap fragrances, especially suitable for soap and cosmetic perfume formulations, acting as a harmonizer in formulations. Alpha-(trichloromethyl)benzyl acetate is a kind of biological materials or organic compounds that are widely used in life science research .
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-
- HY-143209B
-
|
|
Drug Delivery
|
|
DSPE-PEG3400 is a phospholipids-polymer conjugate that can be used in drug delivery applications. DSPE-PEG3400 is a material for the formulation of nanocarriers for achieving prolonged blood circulation time, improved stability and enhanced encapsulation efficiency .
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-
- HY-W441001
-
|
|
Drug Delivery
|
|
DSPE-Fluorescein is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Fluoresceincan be used in drug delivery research .
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-
- HY-166560
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|
|
Drug Delivery
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DSPE-Fluor 488 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Fluor 488can be used in drug delivery research .
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-
- HY-166849
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|
|
Drug Delivery
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|
B22&" is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B22&"can be used in drug delivery research ."
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-
- HY-143692
-
|
|
Drug Delivery
|
|
SQDG inhibits topoisomerase I and P-selectin receptor, exhibits anti-inflammatory, antiviral and antitumor activities. SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations .
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-
- HY-W440987
-
|
|
Drug Delivery
|
|
DOPE-mPEG (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. DOPE-mPEG (MW 1000) can be used in drug delivery research .
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-
- HY-W800741
-
|
|
Drug Delivery
|
|
Undecyl 8-bromooctanoate is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. Undecyl 8-bromooctanoate can be used in drug delivery research .
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-
- HY-W016445
-
|
1-Amino-1-deoxy-D-glucitol, 98%
|
Carbohydrates
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|
D-Glucamine, 98% (1-Amino-1-deoxy-D-glucitol, 98%) is an amino-sugar derivative and can be used as an excipient in pharmaceutical formulations. D-Glucamine, 98% can also be used as a substrate for sugar transporter pathway assay studies .
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-
- HY-W440989
-
|
|
Drug Delivery
|
|
DOPE-mPEG (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-mPEG (MW 5000)can be used in drug delivery research .
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-
- HY-166606
-
|
|
Drug Delivery
|
|
DSPE-polysarcosine66 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-polysarcosine66can be used in drug delivery research .
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-
- HY-166680
-
|
|
Drug Delivery
|
|
DOPE-PEG-FITC (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-FITC (MW 5000)can be used in drug delivery research .
|
-
- HY-166648
-
|
|
Drug Delivery
|
|
DSPE-PEG-Maleimide (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-PEG-Maleimide (MW 2000)can be used in drug delivery research .
|
-
- HY-W440828
-
|
|
Drug Delivery
|
|
DOPE-PEG-COOH (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-COOH (MW 3400)can be used in drug delivery research .
|
-
- HY-W440997
-
|
|
Drug Delivery
|
|
DOPE-PEG-Mal (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Mal (MW 5000)can be used in drug delivery research .
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-
- HY-W250302
-
|
|
Biochemical Assay Reagents
|
|
Methylbenzethonium chloride is a quaternary ammonium compound commonly used as a preservative and disinfectant in a variety of personal care and healthcare products. Methylbenzethonium chloride has several properties that make it suitable for these applications, including its broad-spectrum antibacterial activity against bacteria, viruses and fungi. In addition, it is used as a preservative in cosmetic and pharmaceutical formulations to prevent the growth of microorganisms.
|
-
- HY-W591450
-
|
|
Drug Delivery
|
|
DOPE-PEG-Azide (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Azide (MW 3400)can be used in drug delivery research .
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-
- HY-W440993
-
|
|
Drug Delivery
|
|
DOPE-PEG-Amine (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 5000)can be used in drug delivery research .
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-
- HY-W440996
-
|
|
Drug Delivery
|
|
DOPE-PEG-Mal (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Mal (MW 3400)can be used in drug delivery research .
|
-
- HY-W591448
-
|
|
Drug Delivery
|
|
DOPE-PEG-Azide (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Azide (MW 1000)can be used in drug delivery research .
|
-
- HY-166846
-
|
|
Drug Delivery
|
|
DOPE-PEG-FITC (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-FITC (MW 2000)can be used in drug delivery research .
|
-
- HY-166644
-
|
|
Drug Delivery
|
|
DPPE-PEG-amine (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DPPE-PEG-amine (MW 2000)can be used in drug delivery research .
|
-
- HY-W591451
-
|
|
Drug Delivery
|
|
DOPE-PEG-Azide (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Azide (MW 5000)can be used in drug delivery research .
|
-
- HY-W440992
-
|
|
Drug Delivery
|
|
DOPE-PEG-Amine (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 3400)can be used in drug delivery research .
|
-
- HY-W440826
-
|
|
Drug Delivery
|
|
DOPE-PEG-COOH (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-COOH (MW 1000)can be used in drug delivery research .
|
-
- HY-W440829
-
|
|
Drug Delivery
|
|
DOPE-PEG-COOH (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-COOH (MW 5000)can be used in drug delivery research .
|
-
- HY-W440994
-
|
|
Drug Delivery
|
|
DOPE-PEG-Mal (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Mal (MW 1000)can be used in drug delivery research .
|
-
- HY-W127445
-
|
Docosanamide
|
Drug Delivery
|
|
Behenamide is a fatty acid derived from plants such as rapeseed oil and can be synthesized by a variety of processes. Behenamide has unique properties that make it useful as a slip agent, A lubricant and release agent, it is also used in personal care products, including cosmetics and hair care, as a thickener and emollient because of its ability to improve the consistency and texture of formulations.
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-
- HY-W127627
-
|
|
Co-solvents
|
|
Tween 85 is a nonionic surfactant belonging to the class of ethoxylated sorbitan esters. It is used as an emulsifier and solubilizer in various industries such as pharmaceutical, cosmetic and food. Because of its ability to blend oily and water-based ingredients, Tween 85 is often used in the formulation of creams, lotions and ointments. In addition, it is used as a dispersant for pigments in the production of paints and coatings.
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-
- HY-166857
-
|
|
Drug Delivery
|
|
DMPE-PEG-amine (TFA) (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DMPE-PEG-amine (TFA) (MW 2000)can be used in drug delivery research .
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-
- HY-166654
-
|
|
Drug Delivery
|
|
DSPE-Amide-PEG-Rhodamine (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Amide-PEG-Rhodamine (MW 2000)can be used in drug delivery research .
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-
- HY-W590667
-
|
|
Drug Delivery
|
|
C2 Ceramide-1-phosphate is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. C2 Ceramide-1-phosphatecan be used in drug delivery research .
|
-
- HY-166833
-
|
|
Drug Delivery
|
|
DOPE-PEG-Rhodamine B (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Rhodamine B (MW 5000)can be used in drug delivery research .
|
-
- HY-166651
-
|
|
Drug Delivery
|
|
DSPE-Hyd-PEG-Mal (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Hyd-PEG-Mal (MW 2000)can be used in drug delivery research .
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-
- HY-166852
-
|
|
Drug Delivery
|
|
DOPE-PEG-Cy5 (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Cy5 (MW 2000)can be used in drug delivery research .
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-
- HY-W010900
-
|
|
Biochemical Assay Reagents
|
|
Tetrahexylammonium bromide is a compound that belongs to the class of quaternary ammonium compounds. It is a salt with cationic properties and thus useful in various industrial and biomedical applications. Tetrahexylammonium bromide is commonly used as a phase transfer catalyst to facilitate the movement of reactants between immiscible phases in various organic synthesis reactions. It is also used as a surfactant and emulsifier in the formulation of detergents, personal care products and pharmaceuticals.
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-
- HY-166848
-
|
|
Drug Delivery
|
|
DOPE-PEG-Cy5.5 (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Cy5.5 (MW 2000)can be used in drug delivery research .
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-
- HY-112768
-
|
|
Drug Delivery
|
|
PEG2000-DMPE can be used to synthsis a LNP. PEG2000-DMPE enhances the entrapment efficiency depending on the increasing portion in the liposome. The optimal formulation for animal study is that DMPC/PEG2000-DMPE/CH=50/5/45 at the weight ratio of drug/lipid=1/20 .
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-
- HY-166850
-
|
|
Drug Delivery
|
|
DOPE-PEG-Cy5.5 (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Cy5.5 (MW 5000)can be used in drug delivery research .
|
-
- HY-W012412
-
|
|
Biochemical Assay Reagents
|
|
Tetrapropylammonium chloride is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and is used in various industrial and biomedical applications. Tetrapropylammonium chloride is commonly used as a phase transfer catalyst to facilitate the movement of reactants between immiscible phases in organic synthesis reactions. It is also used as a surfactant in the formulation of personal care products, detergents, textiles and pharmaceuticals. Additionally, it is used in the production of certain types of polymers and resins.
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-
- HY-W013076
-
|
tetra(decyl)ammonium bromide
|
Surfactants
|
|
Tetrakis(decyl)ammonium bromide is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and is used in various industrial and biomedical applications. Tetrakis(decyl)ammonium bromide is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, cleansers and pharmaceutical formulations. It is also used as a phase transfer catalyst in organic synthesis reactions, facilitating the movement of reactants between immiscible phases.
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-
- HY-W738314
-
|
|
Co-solvents
|
|
Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is a chemically modified cyclodextrin with good cosolvent activity. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is widely used in compound formulations to improve the solubility and bioavailability of compounds. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate helps improve the release characteristics of compounds.
|
-
- HY-W250302R
-
|
|
Biochemical Assay Reagents
|
|
Methylbenzethonium (chloride) (Standard) is the analytical standard of Methylbenzethonium (chloride). This product is intended for research and analytical applications. Methylbenzethonium chloride is a quaternary ammonium compound commonly used as a preservative and disinfectant in a variety of personal care and healthcare products. Methylbenzethonium chloride has several properties that make it suitable for these applications, including its broad-spectrum antibacterial activity against bacteria, viruses and fungi. In addition, it is used as a preservative in cosmetic and pharmaceutical formulations to prevent the growth of microorganisms.
|
- HY-W101253
-
|
|
Biochemical Assay Reagents
|
|
Tetraethylammonium (iodide) is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is commonly used as a phase-transfer catalyst in organic synthesis because it facilitates the transfer of reactants between immiscible phases. It can also be used as an electrolyte in electrochemical devices and as a surfactant in detergent formulations. Its unique chemical properties make it an important ingredient in a variety of industrial applications, including pharmaceuticals, agrochemicals, and materials science.
|
- HY-134120
-
|
DL-2-Hydroxystearic acid
|
Drug Delivery
|
|
2-Hydroxystearic acid is an alpha-hydroxy fatty acid commonly used in a variety of personal care products, especially cosmetic and skin care formulations. 2-Hydroxystearic acid has unique chemical properties that make it an effective emulsifier and stabilizer, improving the texture and shelf life of cosmetic products. It also has a potential physiological role in improving skin hydration and elasticity, although its biological function is not fully understood.
|
- HY-115415
-
|
|
Drug Delivery
|
|
1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt has unique chemical properties that make it an effective tool for encapsulating drugs and delivering them to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
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- HY-W127785
-
|
N,N-Dimethyldodecylamine N-oxide; Dodecyldimethylamine oxide
|
Chelators
|
|
N-ethyl-N-oxido-dodecan-1-amine is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power.
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- HY-166992
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|
|
Drug Delivery
|
|
1,2-Dioleoyl-sn-glycero-3-PA (ammonium) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. 1,2-Dioleoyl-sn-glycero-3-PA (ammonium)can be used in drug delivery research .
|
- HY-W101256
-
|
Triethylmethylammonium tetrafluoroborate
|
Cell Assay Reagents
|
|
N,N-Diethyl-N-methylethanaminium tetrafluoroborate is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is commonly used as a phase transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. Additionally, it is used as an electrolyte in electrochemical devices and as a surfactant in detergent formulations. Its unique chemical properties make it an important ingredient in a variety of industrial applications, including pharmaceuticals, agrochemicals, and materials science.
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- HY-W012167
-
|
|
Biochemical Assay Reagents
|
|
N,N,N-Trimethyldecan-1-aminium chloride is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and thus useful in various industrial and biomedical applications. Decyltrimethylammonium chloride is commonly used as a surfactant, emulsifier and disinfectant in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a phase transfer catalyst in organic synthesis reactions, which involves facilitating the movement of reactants between immiscible phases.
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- HY-143702
-
|
NBD-DOTAP
|
Drug Delivery
|
|
Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research .
|
- HY-115369
-
|
|
Drug Delivery
|
|
cis-13,16,19-Docosatrienoic acid methyl ester is an ester form of docosatrienoic acid, a rare omega-3 fatty acid not found in the normal phospholipid polyunsaturated fatty acid pool Easily detectable, it inhibits the binding of [3H]-LTB4 to porcine neutrophils at a concentration of 5 μM. Methyl docosatrienoate is more fat-soluble than the free acid and may be more desirable than the free acid in some formulations.
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- HY-115340
-
|
|
Drug Delivery
|
|
Decanoic acid sodium, also known as Decanoic acid sodium, is a salt of the fatty acid capric acid. It is easily soluble in water and has a slightly soapy smell. Decanoic acid sodium acts as a penetration enhancer, which means it increases the absorption and bioavailability of drugs across biological membranes, including the intestinal epithelium and the blood-brain barrier. This property makes it useful in pharmaceutical formulations to improve drug delivery and effectiveness. Furthermore, Decanoic acid sodium has potential applications in food preservatives and cosmetics due to its antibacterial properties.
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- HY-W007174A
-
|
|
Carbohydrates
|
|
1,4-Anhydro-D-xylitol is a compound belonging to the class of sugar alcohols. It is derived from xylitol, a natural sweetener found in many fruits and vegetables. 1,4-Anhydro-D-xylitol is commonly used as a low-calorie sweetener and excipient in the food and pharmaceutical industries, and as a filler or binder in pharmaceutical formulations. It has also been investigated for its potential use in the development of biodegradable plastics and other sustainable materials.
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- HY-125619
-
|
|
Drug Delivery
|
|
1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
|
- HY-W008974
-
|
|
Surfactants
|
|
3-(Dimethyl(octadecyl)ammonio)propane-1-sulfonate is a class of quaternary ammonium compounds. It is a surfactant and cationic detergent with amphiphilic properties and therefore useful in various industrial and biomedical applications. 3-(Dimethyl(octadecyl)ammonium)propane-1-sulfonate is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a reagent in analytical chemistry, especially in the analysis of proteins and DNA.
|
- HY-137499
-
|
|
Drug Delivery
|
|
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
|
- HY-W250168
-
|
Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10
|
Surfactants
|
|
Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.
|
- HY-W127785R
-
|
|
Chelators
|
|
N-ethyl-N-oxido-dodecan-1-amine (Standard) is the analytical standard of N-ethyl-N-oxido-dodecan-1-amine. This product is intended for research and analytical applications. N-ethyl-N-oxido-dodecan-1-amine is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power.
|
- HY-141582
-
|
N-Stearoyl phytosphingosine
|
Drug Delivery
|
|
C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. Cer(t18:0/18:0) consists of a phytosphingosine backbone amine linked to a C18 fatty acid chain. Cer(t18:0/18:0) has the function of regulating apoptosis, cell differentiation, proliferation of smooth muscle cells and inhibition of mitochondrial respiratory chain. It also suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue. Formulations containing cer(t18:0/18:0) have been used as skin protectants in cosmetics as they reduce water loss and prevent epidermal dehydration and irritation.
|
- HY-W012952R
-
|
|
Biochemical Assay Reagents
|
|
(2E,4E)-Hepta-2,4-dienal (Standard) is the analytical standard of (2E,4E)-Hepta-2,4-dienal. This product is intended for research and analytical applications. (2E,4E)-Hepta-2,4-dienal is a naturally occurring organic compound that belongs to the group of aldehydes. It is an unsaturated aldehyde with two conjugated double bonds, giving it unique chemical and physical properties. (2E,4E)-Hepta-2,4-dienal is commonly found in various plant sources, especially in spices such as parsley and coriander. It is used as a flavoring agent and food additive in the formulation of various foods such as baked goods, snacks and beverages. It is also used in the fragrance industry, especially in the production of perfume and cologne.
|
-
- HY-K0501
-
Maximum Cited Publications
220 Publications Verification
|
|
MCE qPCR Master Mix is provided as a simple-to-use, stabilized 2× formulation that includes all components for qPCR except sample DNA, primers and water.
|
-
- HY-K0533
-
1 Publications Verification
|
|
2× High-Fidelity PCR Master Mix is provided as a simple-to-use, stabilized 2× formulation that includes all components for PCR except sample DNA, primers and water.
|
-
- HY-K0510A
-
|
|
|
MCE RT Master Mix for qPCR II is a convenient, ready-to-use formulation for reverse transcription. With advanced reverse transcriptase, this kit can synthesize cDNA more rapidly, more specifically.
|
-
- HY-K0531
-
|
|
|
2× PCR Master Mix (with Dye) is provided as a simple-to-use, stabilized 2× formulation that includes all components for PCR except sample DNA, primers and water, in which bromophenol blue dye is included.
|
-
- HY-K0523
-
|
|
|
SYBR Green qPCR Master Mix (No ROX) is provided as a simple-to-use, stabilized 2× formulation that includes all components for qPCR except sample DNA, primers and water, in which no ROX Reference Dye is included.
|
-
- HY-K0532
-
2 Publications Verification
|
|
2× Fast PCR Master Mix (with Dye) is provided as a simple-to-use, stabilized 2× formulation that includes all components for fast PCR except sample DNA, primers and water, in which bromophenol blue dye is included.
|
-
- HY-K0521
-
2 Publications Verification
|
|
SYBR Green qPCR Master Mix (High ROX) is provided as a simple-to-use, stabilized 2× formulation that includes all components for qPCR except sample DNA, primers and water, in which High ROX Reference Dye is included.
|
-
- HY-K0522
-
|
|
|
SYBR Green qPCR Master Mix (Low ROX) is provided as a simple-to-use, stabilized 2× formulation that includes all components for qPCR except sample DNA, primers and water, in which Low ROX Reference Dye is included.
|
-
- HY-K1105A
-
|
|
|
MCE One Step Colored Rapid Gel Preparation Kit (12.5%) uses pre-mixed formulations of the upper gel and lower gel. Simply mix the reagents in pairs, add modified coagulation agent, and the gel will form quickly and easily.
|
-
- HY-K0511A
-
|
|
|
MCE RT Master Mix for qPCR II is a convenient, ready-to-use formulation for reverse transcription and can eliminate genomic DNA (gDNA) contaminations in RNA samples. With updated reverse transcriptase, this kit can synthesize cDNA more rapidly, more specifically.
|
-
- HY-K3014
-
|
|
|
Bi-27 Additive (50×), Vitamin A-Free is a customized variant of the standard Bi-27 formulation with vitamin A removed as a supplement for neuronal cell culture to support the low- or high-density growth and short- or long-term viability of embryonic.
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-
- HY-K0501A
-
|
|
|
MCE SYBR Green qPCR Master Mix (Universal) is compatible with all qPCR instruments. 2× ready-to-use formulations which consist of antibody-mediated hot start polymerase, MgCl2, dNTPs and a proprietary reaction buffer, produce optimal results in qPCR experiments.
|
-
- HY-K0511
-
|
|
|
MCE RT Master Mix for qPCR (gDNA digester plus) is a convenient, ready-to-use formulation for reverse transcription and can eliminate genomic DNA (gDNA) contaminations in RNA samples. The cDNA product can be directly applied as a template in a standard PCR and real time quantitative PCR (qPCR).
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P99974
-
|
Nanoparticle albumin-bound Paclitaxel; Nanoparticle albumin-bound ABI-007
|
Microtubule/Tubulin
Apoptosis
Autophagy
|
Cancer
|
|
Nab-Paclitaxel is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel, in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel was associated with higher response rates and better tolerability, with favorable pharmacokinetic properties . (The product size below only indicate the effective content of Paclitaxel. The actual albumin quality depends on the batch. The ratio of each component in this product is Paclitaxel: albumin = 1:7-1:11).
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-B1278A
-
-
-
- HY-B1384
-
-
-
- HY-W196368
-
-
-
- HY-N12028
-
-
-
- HY-120435
-
-
-
- HY-N0711
-
|
Cymophenol
|
Structural Classification
Monophenols
Preservatives
Classification of Application Fields
Labiatae
Phenols
Plants
Inflammation/Immunology
Disease Research Fields
Food Research
|
Notch
Apoptosis
Fungal
Endogenous Metabolite
Bacterial
|
|
Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .
|
-
-
- HY-137499
-
-
-
- HY-B1278AR
-
-
-
- HY-114335
-
-
-
- HY-N0711R
-
|
|
Structural Classification
Monophenols
Labiatae
Phenols
Plants
|
Notch
Apoptosis
Fungal
Endogenous Metabolite
Bacterial
|
|
Carvacrol (Standard) is the analytical standard of Carvacrol. This product is intended for research and analytical applications. Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .
|
-
-
- HY-N3387
-
-
-
- HY-W012952R
-
|
|
Structural Classification
Natural Products
Vaccinium macrocarpon Aiton
Source classification
Ericaceae
Plants
|
Biochemical Assay Reagents
|
|
(2E,4E)-Hepta-2,4-dienal (Standard) is the analytical standard of (2E,4E)-Hepta-2,4-dienal. This product is intended for research and analytical applications. (2E,4E)-Hepta-2,4-dienal is a naturally occurring organic compound that belongs to the group of aldehydes. It is an unsaturated aldehyde with two conjugated double bonds, giving it unique chemical and physical properties. (2E,4E)-Hepta-2,4-dienal is commonly found in various plant sources, especially in spices such as parsley and coriander. It is used as a flavoring agent and food additive in the formulation of various foods such as baked goods, snacks and beverages. It is also used in the fragrance industry, especially in the production of perfume and cologne.
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-Y0921S2
-
|
|
|
(±)-1,2-Propanediol-d6 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents .
|
-
-
- HY-B0216S
-
|
|
|
Ethynyl Estradiol-d4 is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-Y0921S1
-
|
|
|
(±)-1,2-Propanediol-d2 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents .
|
-
-
- HY-Y0921S
-
|
|
|
(±)-1,2-Propanediol-d8 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents .
|
-
-
- HY-B1278AS
-
|
|
|
DL-α-Tocopherol acetate- 13C4,d6 is the deuterium and 13C labeled DL-α-Tocopherol acetate[1]. DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition[2][3].
|
-
-
- HY-159176
-
|
|
|
Antitumor agent-183 (compound 3f) has antitumor activity with metabolic stability. Antitumor agent-183 inhibits cancer cell growth, with IC50s less than 5 nM for A549, HCT116, and HS578T cells. The albumin-bound nanoparticle formulation of Antitumor agent-183 has prolonged retention in the tumor tissues .
|
-
-
- HY-141582S
-
|
|
|
Ceramide 3-d3 (N-Stearoyl phytosphingosine-d3) is deuterium labeled Ceramide 3. C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. Cer(t18:0/18:0) consists of a phytosphingosine backbone amine linked to a C18 fatty acid chain. Cer(t18:0/18:0) has the function of regulating apoptosis, cell differentiation, proliferation of smooth muscle cells and inhibition of mitochondrial respiratory chain. It also suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue. Formulations containing cer(t18:0/18:0) have been used as skin protectants in cosmetics as they reduce water loss and prevent epidermal dehydration and irritation .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-B0216S
-
|
17α-Ethynylestradiol-d4; Ethynylestradiol-d4
|
|
Alkynes
|
|
Ethynyl Estradiol-d4 is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-153235
-
|
|
|
mRNA
|
|
COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein. COVID-19 Spike Protein undertakes the functions of virus binding with host cell receptors, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design. COVID-19 Spike Protein mRNA-LNP can be used for RNA delivery, vaccine formulation and design targeting SARS-CoV-2 .
|
-
- HY-B2221B
-
|
Hydroxyethyl pectin glycosidase
|
|
Thickeners
|
|
Hydroxyethyl cellulose is a non-ionic, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
|
-
- HY-145794
-
|
|
|
Cationic Lipids
|
|
ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery.
|
-
- HY-Y0873A
-
|
Polyethylene glycol 400
|
|
Emulsifiers
Surfactants
|
|
PEG400 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances. PEG400 is widely used in a variety of pharmaceutical formulations.
|
-
- HY-112768
-
|
|
|
Pegylated Lipids
|
|
PEG2000-DMPE can be used to synthsis a LNP. PEG2000-DMPE enhances the entrapment efficiency depending on the increasing portion in the liposome. The optimal formulation for animal study is that DMPC/PEG2000-DMPE/CH=50/5/45 at the weight ratio of drug/lipid=1/20 .
|
-
- HY-115415
-
|
|
|
Phospholipids
|
|
1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt has unique chemical properties that make it an effective tool for encapsulating drugs and delivering them to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
|
-
- HY-143702
-
|
NBD-DOTAP
|
|
Cationic Lipids
|
|
Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research .
|
-
- HY-125619
-
|
|
|
Phospholipids
|
|
1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
|
-
- HY-156100
-
|
|
|
Cationic Lipids
|
|
C12-4 is an ionizable lipid for lipid nanoparticles (LNPs) formulation.
|
-
- HY-160705
-
|
|
|
Cationic Lipids
|
|
PNI 132, an ionizable lipid derived from the patent WO2020252589A, is useful in the formulation of lipid nanoparticles.
|
-
- HY-112766
-
|
|
|
Phospholipids
|
|
DPyPE is a neutral phosphatidylethanolamine lipid composed of a polyisoprene alkyl chain with two pyridine-containing phosphine ligands. DPyPE is mainly used in liposome formulations and to enhance the efficiency of gene delivery in vitro and in vivo. For example, DPyPE can be mixed with cationic lipids such as VC1052 (HY-156616) (in a 1:1 ratio) to form the vaccine adjuvant Vaxfectin (HY-142998). DPyPE assists VC1052 in binding to negatively charged pDNA to form a uniform liposome complex by regulating the fluidity and stability of the liposome membrane .
|
-
- HY-137499
-
|
|
|
Cationic Lipids
|
|
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
|
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