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erosions

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (1) Bcr-Abl (2) Biochemical Assay Reagents (1) DNA/RNA Synthesis (1) Drug Isomer (1) Histamine Receptor (3) Nuclear Factor of activated T Cells (NFAT) (1) Phosphatase (3) Prostaglandin Receptor (1) PTHR (1) Reference Standards (3) SARS-CoV (2) Ser/Thr Protease (1) Thyroid Hormone Receptor (1) TNF Receptor (1) TRP Channel (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Endocrinology (2) Infection (1) Inflammation/Immunology (16) Metabolic Disease (2) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119580

Leucocyanidin 1 Publications Verification	Others	Inflammation/Immunology
Leucocyanidin is an active anti-ulcerogenic ingredient was extracted from Litchi Chinensis. Leucocyanidin demonstrates a significant protective effect against Aspirin-induced erosions in rat models .

HY-119580B

(+)-Leucocyanidin 2,3-trans-3,4-trans-Leucocyanidin; 3,4-trans-Leucocyanidin; (2R,3S,4R)-Leucocyanidin	Drug Isomer	Inflammation/Immunology
(+)-Leucocyanidin is the isoform of Leucocyanidin (HY-119580), is an active anti-ulcerogenic ingredient was extracted from Litchi Chinensis. Leucocyanidin demonstrates a significant protective effect against Aspirin-induced erosions in rat models .

HY-119580R

Leucocyanidin (Standard)	Reference Standards Others	Inflammation/Immunology
Leucocyanidin (Standard) is the analytical standard of Leucocyanidin. This product is intended for research and analytical applications. Leucocyanidin is an active anti-ulcerogenic ingredient was extracted from Litchi Chinensis. Leucocyanidin demonstrates a significant protective effect against Aspirin-induced erosions in rat models[1].

HY-P99578

Tanfanercept HL036337; HBM9036	TNF Receptor	Inflammation/Immunology
Tanfanercept (HL036337) is an TNF-α receptor fusion protein that targets TNF-α. Tanfanercept is effective in ameliorating corneal erosions in a dry eye (DE) mouse model .

HY-13723A

Pimecrolimus hydrate SDZ-ASM 981 hydrate	Phosphatase	Inflammation/Immunology
Pimecrolimus hydrate (SDZ-ASM 981 hydrate) is a potent, nonsteroid and orally active calcineurin inhibitor. Pimecrolimus hydrate shows anti-inflammatory activity. Pimecrolimus hydrate has the potential for the research of atopic dermatitis and oral erosive lichen planus .

HY-P4800

Osteostatin (human) Human PTHrP(107-139)	Thyroid Hormone Receptor	Metabolic Disease Inflammation/Immunology
Osteostatin (human), a fragment of parathyroid hormone-related protein (PTHrP) 107-139, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis .

HY-121399

Gizzerosine	Histamine Receptor	Neurological Disease
Gizzerosine is an H₂ receptor agonist. It can stimulate the gastric acid secretion of broiler chickens, thus causing gizzard erosion in them. Gizzerosine has significant research value in the fields of agricultural farming and feed science .

HY-135186

L-Monomenthyl glutarate	Biochemical Assay Reagents	Others
L-Monomenthyl glutarate is a menthol coolant. L-Monomenthyl glutarate has a strong volatility and permeability, high concentration of menthol vapor has a strong irritation and erosion effect on human skin and mucosa. L-Monomenthyl glutarate can be used in food, tobacco and other daily chemical products .

HY-P4684

Osteostatin PTHrP (107–111)	PTHR	Inflammation/Immunology
Osteostatin, a fragment of parathyroid hormone-related protein (PTHrP) 107-111, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis, inhibits collagen-induced arthritis and inhibits osteoclastic bone resorption directly. Osteostatin can be used for inflammation and immunology research .

HY-17491

Proquazone RU 43-715; Sandoz-43-715	Others	Inflammation/Immunology
Proquazone (RU 43-715) is a chemically distinctive non-steroidal anti-inflammatory agent (NSAID). unlike most other NSAIDs, Proquazone does not have a free acid group in its structure. Proquazone may inhibit or arrest progression of bone erosions. Proquazone is an orally active anti-inflammatory, analgesic and anti-pyretic agent .

HY-W641445

ELP-004	TRP Channel	Inflammation/Immunology
ELP-004 is a TRPC channel inhibitor and inhibtis TRPC channel-mediated Ca ²⁺ entry. ELP-004 is an osteoclast inhibitor and inhibits osteoclast differentiation. ELP-004 inhibits basal Ca ²⁺ and related NFATc1 translocation in inflammatory osteoclastogenesis. ELP-004 reduces bone erosion in a mouse model of rheumatoid arthritis .

HY-108308

Ibuprofen guaiacol ester Methoxybutropate; AF 2259; Metoxibutropate	Prostaglandin Receptor	Metabolic Disease Inflammation/Immunology
Ibuprofen guaiacol ester (AF 2259; Metoxibutropate) is a potent and orally active prostaglandin synthesis inhibitor. Ibuprofen guaiacol ester has the potential for the research of edema and fever .

HY-122762

Cetraxate hydrochloride DV-1006	Ser/Thr Protease	Inflammation/Immunology
Cetraxate hydrochloride (DV-1006), an orally active anti-ulcer agent with mucosal protective effects, can be used for gastric ulcers research . Cetraxate hydrochloride is a potent acrosomal proteinase acrosin inhibitor with a K_i and an IC₅₀ of 0.94 μM and 3.3 μM, respectively .

HY-11007

GNF-2 2 Publications Verification	Bcr-Abl SARS-CoV	Cancer
GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC₅₀ of 138 nM .

HY-11007R

GNF-2 (Standard)	Bcr-Abl SARS-CoV	Cancer
GNF-2 (Standard) is the analytical standard of GNF-2. This product is intended for research and analytical applications. GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC50 of 138 nM .

HY-B0310

Nizatidine	Histamine Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Nizatidine is a potent and orally active histamine H₂ receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models .

HY-B0310R

Nizatidine (Standard)	Reference Standards Histamine Receptor	Inflammation/Immunology Endocrinology Cancer
Nizatidine (Standard) is the analytical standard of Nizatidine. This product is intended for research and analytical applications. Nizatidine is a potent and orally active histamine H₂ receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models .

HY-13723R

Pimecrolimus (Standard) SDZ-ASM 981 (Standard)	Reference Standards Phosphatase	Inflammation/Immunology
Pimecrolimus (Standard) is the analytical standard of Pimecrolimus. This product is intended for research and analytical applications. Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with a Ki of 117 nM. Pimecrolimus shows anti-inflammatory activity .

HY-13723

Pimecrolimus 3 Publications Verification SDZ-ASM 981	Phosphatase	Inflammation/Immunology
Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with a K_i of 117 nM. Pimecrolimus shows anti-inflammatory activity .

HY-N0656

Usnic acid 1 Publications Verification	Bacterial DNA/RNA Synthesis Nuclear Factor of activated T Cells (NFAT) Apoptosis	Infection Inflammation/Immunology Cancer
Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase .

Cat. No.	Product Name	Target	Research Area

HY-P4800

Osteostatin (human) Human PTHrP(107-139)	Thyroid Hormone Receptor	Metabolic Disease Inflammation/Immunology
Osteostatin (human), a fragment of parathyroid hormone-related protein (PTHrP) 107-139, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis .

HY-P4684

Osteostatin PTHrP (107–111)	PTHR	Inflammation/Immunology
Osteostatin, a fragment of parathyroid hormone-related protein (PTHrP) 107-111, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis, inhibits collagen-induced arthritis and inhibits osteoclastic bone resorption directly. Osteostatin can be used for inflammation and immunology research .

Cat. No.	Product Name	Target	Research Area

HY-P99578

Tanfanercept HL036337; HBM9036	TNF Receptor	Inflammation/Immunology
Tanfanercept (HL036337) is an TNF-α receptor fusion protein that targets TNF-α. Tanfanercept is effective in ameliorating corneal erosions in a dry eye (DE) mouse model .

Leucocyanidin 1 Publications Verification	Structural Classification Classification of Application Fields Litchi Chinensis Sonn. Source classification Plants Flavonoids Microorganisms Flavanols Sapindaceae Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Others
Leucocyanidin is an active anti-ulcerogenic ingredient was extracted from Litchi Chinensis. Leucocyanidin demonstrates a significant protective effect against Aspirin-induced erosions in rat models .

Usnic acid 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Plants Infection Usnea diffracta Vain. Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Usneaceae	Bacterial DNA/RNA Synthesis Nuclear Factor of activated T Cells (NFAT) Apoptosis
Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase .

Leucocyanidin (Standard)	Structural Classification Flavonoids Microorganisms Litchi Chinensis Sonn. Flavanols Source classification Sapindaceae Phenols Polyphenols Plants	Reference Standards Others
Leucocyanidin (Standard) is the analytical standard of Leucocyanidin. This product is intended for research and analytical applications. Leucocyanidin is an active anti-ulcerogenic ingredient was extracted from Litchi Chinensis. Leucocyanidin demonstrates a significant protective effect against Aspirin-induced erosions in rat models[1].

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erosions

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

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Natural
Products