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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

drug delivery carrier

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Intermediate (1) Radionuclide-Drug Conjugates (RDCs) (1) Apoptosis (1) Autophagy (1) Bacterial (9) Biochemical Assay Reagents (31) CDK (1) Endogenous Metabolite (4) Interleukin Related (2) LDLR (1) Liposome (12) NF-κB (1) NO Synthase (2) Parasite (1) Reference Standards (1) TNF Receptor (2) Tyrosinase (1)
By Research Areas:	Cancer (4) Infection (7) Inflammation/Immunology (5)
Oligonucleotides:	Fluorescent Lipids (3) Pegylated Lipids (7) Liposomal Film-forming Agents (1) Emulsifiers (2) Phospholipids (1) Polymers (3)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Oligonucleotides

Targets Recommended: Drug Intermediate Drug Isomer Drug Derivative Drug Metabolite Antibody-Drug Conjugates (ADCs) Peptide-Drug Conjugates (PDCs) Radionuclide-Drug Conjugates (RDCs) Drug-Linker Conjugates for ADC ADC Linker

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2247A

PLGA (75:25) 1 Publications Verification poly(lactic-co-glycolic acid) (75:25)	Biochemical Assay Reagents	Others
PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .

HY-164657

Polyamidoamine (20% in methanol) PAMAM	Radionuclide-Drug Conjugates (RDCs)	Cancer
Polyamidoamine (PAMAM) (20% in methanol) is a new type of drug carrier that has drug encapsulation capabilities internally and biocompatibility on the surface, and can be used as a drug delivery system.

HY-P10128

GE11 1 Publications Verification	Biochemical Assay Reagents	Inflammation/Immunology
GE11 is a active peptide and combines with colloidal drug delivery systems as smart carriers for antitumor drugs and can be used for cancer study .

HY-Y0873O

PEG35000 Polyethylene glycol 35000	Biochemical Assay Reagents	Others
PEG35000 is a polyethylene glycol with a molecular weight of 35,000 that can be used as a carrier material and modifier in drug delivery systems .

HY-112111

Poly-L-Glutamic acid (MW 700000)	Biochemical Assay Reagents	Cancer
Poly-L-Glutamic acid (MW 700000) is biochemical reagent.Poly-L-Glutamic acid can be used as the drug carrier for targeted delivery of anticancer agents .

HY-P10502

L57	LDLR	Others
L57 exhibits high affinity to the low-density lipoprotein receptor-related protein 1 (LRP1) with K_i of 45 nM. L57 exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 can be utilized as the carrier for CNS drug delivery .

HY-144027

Dolichol (13~21)	Biochemical Assay Reagents	Others
Dolichol (13~21) is a lipid carrier containing isoprene units. Dolichol (13~21) can be used for liposomes applied in drug delivery .

HY-144008

C8 PEG-Ceramide	Liposome	Others
C8 PEG-Ceramide is a lipid product. C8 PEG-Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .

HY-144008A

C8 PEG5000 Ceramide	Liposome	Others
C8 PEG5000 Ceramide is a lipid product. C8 PEG5000 Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .

HY-158209

Block polyoxyethylene-polyoxypropylene	Biochemical Assay Reagents	Others
Block polyoxyethylene-polyoxypropylene is a block copolymer composed of hydrophilic polyoxyethylene (POE) and hydrophobic polyoxypropylene (POP), which can be used to prepare biological materials such as emulsifiers, drug delivery carriers, and stabilizers .

HY-W440915

DSPE-PEG-FITC (MW 2000)	Liposome	Others
DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-W440917

DSPE-PEG-FITC (MW 5000)	Liposome	Others
DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-W440916

DSPE-PEG-FITC (MW 3400)	Liposome	Others
DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-W763557B

Poly(ethylene glycol) methacrylate (MW 500)	Biochemical Assay Reagents	Others
Poly(ethylene glycol) methacrylate (MW 500) is a monomethacrylate functionalized PEG, which is used to prepare composite materials, such as Poly(ethylene glycol) methacrylate-chitosan, and can be used as an ocular drug delivery carrier .

HY-W763557A

Poly(ethylene glycol) methacrylate (MW 360)	Biochemical Assay Reagents	Others
Poly(ethylene glycol) methacrylate (MW 360) is a monomethacrylate functionalized PEG, which is used to prepare composite materials, such as Poly(ethylene glycol) methacrylate-chitosan, and can be used as an ocular drug delivery carrier .

HY-W441009A

DSPE-PEG-Maleimide (MW 3400) ammonium	Liposome	Others
DSPE-PEG-Maleimide (MW 3400) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 3400) ammonium can be used in drug delivery research .

HY-166648A

DSPE-PEG-Maleimide ammonium (MW 2000)	Liposome	Others
DSPE-PEG-Maleimide (ammonium) (MW 2000) has DSPE phospholipids and maleimide to prepare nanostructured lipid carriers. DSPE-PEG-Maleimide (ammonium) (MW 2000) can be used in drug delivery research .

HY-112624B

Dextran T70 (MW 70,000) Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)	Bacterial	Others
Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.

HY-112760

18:0 mPEG2000 PE sodium 1 Publications Verification DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium	Liposome	Others
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .

HY-W250313

Polylactic acid PLA	Biochemical Assay Reagents	Others Cancer
Polylactic acid (PLA) is a biodegradable and biocompatible polymer widely used as a carrier for drug delivery systems and a structural material for tissue engineering and medical implants. Polylactic acid acts as a controlled release matrix through the hydrolysis mechanism of ester bonds, gradually releasing the encapsulated drug and metabolizing to non-toxic lactic acid. Polylactic acid has adjustable degradation rate, mechanical properties and the ability to composite with other polymers, and can be used in local or systemic drug delivery, orthopedic fixation devices and 3D printed bone regeneration scaffolds[1][2].

HY-D1005A5

Poloxamer 123 (L43) PEG-PPG-PEG, 1850 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 123 L43 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1850. Poloxamer 123 L43 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A13

Poloxamer 215 (P75) PEG-PPG-PEG, 4150 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 215 P75 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4150. Poloxamer 215 P75 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A20

Poloxamer 334 (P104) PEG-PPG-PEG, 5900 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 334 P104 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 5900. Poloxamer 334 P104 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A11

Poloxamer 185 (P65) PEG-PPG-PEG, 3400 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 185 P65 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 3400. Poloxamer 185 P65 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A7

Poloxamer 125 (L45) PEG-PPG-PEG, 2400 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 125 L45 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2400. Poloxamer 125 L45 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A15

Poloxamer 234 (P84) PEG-PPG-PEG, 4200 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 234 P84 is is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4200. Poloxamer 234 P84 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A12

Poloxamer 212 (L72) PEG-PPG-PEG, 2750 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 212 L72 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2750. Poloxamer 212 L72 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A2

Poloxamer 105 (L35) PEG-PPG-PEG, 1900 (Average)	Biochemical Assay Reagents	Others
Poloxamer 105 L35 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1900 Da. Poloxamer 105 L35 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-112624K

Dextran T5 (MW 5,000) Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)	Apoptosis Autophagy	Others
Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-156598

1,3-Bis(carboxyphenoxy)propane	Biochemical Assay Reagents	Others
1,3-Bis (carboxyphenoxy) propane is one of the monomer raw materials for aromatic polyanhydrides. 1,3-Bis (carboxyphenoxy) propane has been used as biodegradable carriers for drug delivery applications. 1,3-Bis (carboxyphenoxy) can be used for implant related research .

HY-112624J

Dextran T4 (MW 4,000) Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)	Bacterial	Others
Dextran 4,000 is a mucus rheology modifier. The dextran molecules in Dextran 4,000 can reduce the cross-link density of mucus through osmotic effects and hydrogen bond substitution, and reduce viscoelasticity and improve the mucociliary/cough clearance index by destroying the DNA-mucin network structure in mucus. Dextran 4,000 has the ability to improve the rheological properties and clearance ability of cystic fibrosis (CF) sputum, and can be used in the study of inhalation therapy or aerosol delivery of mucostatic respiratory diseases. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-W440903

DSPE-PEG-IA (MW 5000)	Biochemical Assay Reagents	Others
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.

HY-W440926

Stearic acid-PEG-NHS (MW 1000)	Biochemical Assay Reagents Liposome	Others
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.

HY-D1005A17

Poloxamer 238 (F88) PEG-PPG-PEG, 11400 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 238 F88 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 11400. Poloxamer 238 F88 reduces the aggregation of red blood cells. Poloxamer 238 F88 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-W440907

DSPE-PEG-Vinylsulfone (MW 5000)	Biochemical Assay Reagents	Others
DSPE-PEG-Vinylsulfone, MW 5000 is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine. Reagent grade, for research use only.

HY-D1005A9

Poloxamer 183 (L63) PEG-PPG-PEG, 2650 (Averag)	Biochemical Assay Reagents Bacterial	Infection
Poloxamer 183 L63 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2650. Poloxamer 183 L63 exhibits antimicrobial activity, that inihibits 83% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 183 L63 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A4

Poloxamer 122 (L42) PEG-PPG-PEG, 1630 (Averag)	Biochemical Assay Reagents Bacterial	Infection
Poloxamer 122 L42 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1630. Poloxamer 122 L42 exhibits antimicrobial activity, that inihibits 56% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 122 L42 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A8

Poloxamer 181 (L61) PEG-PPG-PEG, 2000 (Averag)	Biochemical Assay Reagents Bacterial	Infection
Poloxamer 181 L61 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2000. Poloxamer 181 L61 exhibits antimicrobial activity, that inihibits 91% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 181 L61 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A19

Poloxamer 333 (P103) PEG-PPG-PEG, 4950 (Averag)	Biochemical Assay Reagents Bacterial	Infection
Poloxamer 333 P103 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4950. Poloxamer 333 P103 exhibits antimicrobial activity, that inihibits 90% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 333 P103 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-112624E

Dextran T0.8 (MW 800) Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)	Biochemical Assay Reagents	Others
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-N0322B

Cholesterol (Excipient)	Liposome Endogenous Metabolite	Others
Cholesterol Excipient is a component of the cell membrane and a precursor of some hormones, vitamin D and bile acid, with oral activity. Cholesterol Excipient is a drug delivery carrier based on the lipid environment of the cell membrane. Due to its amphiphilicity, good biocompatibility and biodegradability, it can be used as an excipient in drug preparations. Cholesterol Excipient can self-assemble into delivery systems such as micelles, nanoparticles, and liposomes, and achieve controlled drug release by regulating membrane fluidity or responding to the microenvironment. It has the characteristics of high drug loading efficiency and good biocompatibility. Cholesterol Excipient is mainly used for research in the fields of targeted delivery of anticancer, antibacterial, antiviral drugs and treatment of skin diseases. Cholesterol itself is also an endogenous regulator involved in the cleavage of amyloid precursor protein (APP) mediated by β-secretase and intestinal absorption, as well as an endogenous estrogen-related receptor α (ERRα) agonist. Cholesterol affects the subcellular localization of APP processing enzymes by regulating the cell membrane lipid environment, which can promote the production of β-amyloid protein and its adsorption and removal by probiotics. It is used to study the pathogenesis of Alzheimer's disease (AD) and the cholesterol-lowering function of probiotics[1][2][3][4][5].

HY-D1005A21

Poloxamer 335 (P105) PEG-PPG-PEG, 6500 (Averag)	Biochemical Assay Reagents Bacterial	Infection
Poloxamer 335 P105 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 6500. Poloxamer 335 P105 exhibits antimicrobial activity, that inihibits 86% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 334 P104 exhibits muscular toxicity. Poloxamer 334 P104 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-128754

Monoolein	Endogenous Metabolite Interleukin Related TNF Receptor NO Synthase	Inflammation/Immunology
Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .

HY-128754R

Monoolein (Standard)	Endogenous Metabolite Interleukin Related TNF Receptor NO Synthase	Inflammation/Immunology
Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .

HY-112624I

Dextran T3 (MW 3,000) Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)	Bacterial	Others
Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-112624H

Dextran T2 (MW 2,000) Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)	Biochemical Assay Reagents	Others
Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM₂), and Isomaltotriose (IM₃). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .

HY-N0322BR

Cholesterol (Excipient) (Standard)	Reference Standards Liposome Endogenous Metabolite	Others
Cholesterol (Excipient) (Standard) is the analytical standard of Cholesterol (Excipient) (HY-N0322B). This product is intended for research and analytical applications. Cholesterol Excipient is a component of the cell membrane and a precursor of some hormones, vitamin D and bile acid, with oral activity. Cholesterol Excipient is a drug delivery carrier based on the lipid environment of the cell membrane. Due to its amphiphilicity, good biocompatibility and biodegradability, it can be used as an excipient in drug preparations. Cholesterol Excipient can self-assemble into delivery systems such as micelles, nanoparticles, and liposomes, and achieve controlled drug release by regulating membrane fluidity or responding to the microenvironment. It has the characteristics of high drug loading efficiency and good biocompatibility. Cholesterol Excipient is mainly used for research in the fields of targeted delivery of anticancer, antibacterial, antiviral drugs and treatment of skin diseases. Cholesterol itself is also an endogenous regulator involved in the cleavage of amyloid precursor protein (APP) mediated by β-secretase and intestinal absorption, as well as an endogenous estrogen-related receptor α (ERRα) agonist. Cholesterol affects the subcellular localization of APP processing enzymes by regulating the cell membrane lipid environment, which can promote the production of β-amyloid protein and its adsorption and removal by probiotics. It is used to study the pathogenesis of Alzheimer's disease (AD) and the cholesterol-lowering function of probiotics[1][2][3][4][5].

HY-158255

mPEG-PLGA (2000-80000) (LA/GA 50:50)	Biochemical Assay Reagents	Others
mPEG-PLGA (2000-80000) (LA/GA 50:50) is a copolymer, which consists of hydrophilic mPEG and biodegradable PLGA (molar ratio is 50:50) with a molecular weight of 2000 (mPEG) + 80000 (PLGA). mPEG-PLGA (2000-80000) (LA/GA 50:50) forms nanoparticles or microparticles, which is stable in aqueous solution at different pH values and elevated temperatures as well as in serum. mPEG-PLGA (2000-80000) (LA/GA 50:50) is utilized as carrier material in drug delivery systems .

HY-D1005A10

Poloxamer 184 (L64) PEG-PPG-PEG, 2900 (Averag)	Biochemical Assay Reagents Bacterial	Infection Inflammation/Immunology
Poloxamer 184 L64 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2900. Poloxamer 184 L64 exhibts short-term dermal toxicity characterized by slight erythema and intradermal inflammatory response. Poloxamer 184 L64 exhibits antimicrobial activity, that inihibits 60% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 184 L64 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-W127512

5β-Cholanic acid	Drug Intermediate	Others
5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .

Cat. No.	Product Name

HY-L214

Liposome Library

143 compounds

Liposomes are spherical or multilayered spherical vesicles formed by the self-assembly of diacyl chain phospholipids (lipid bilayers) in aqueous solutions, which can be made from natural or synthetic phospholipids and exhibit good biocompatibility and low toxicity. They can serve as delivery carriers for various bioactive substances (such as drugs, proteins, nucleic acids, etc.) and are widely used in biomedical and chemical research. The main advantages of liposomes include 1) Protective effect: Their bilayer structure can protect encapsulated molecules from enzymatic degradation, oxidation, and other influences, extending stability and activity; 2) Active targeting: Surface modifications enable active targeting, enhancing the concentration of drugs or molecules in specific tissues or cells; 3) Customizability: The composition and structure of liposomes can be adjusted according to needs, such as altering phospholipid types or adding targeting ligands. These properties make liposomes highly valuable in developing novel drug delivery systems, serving as nucleic acid carriers for gene transfection, studying cellular uptake mechanisms and drug release kinetics, as well as developing functional food additives to improve the bioavailability of nutritional components.

MCE contains 143 liposome compounds, which is a good tool for lipidomic-related studies.

Cat. No.	Product Name	Type

HY-W440916

DSPE-PEG-FITC (MW 3400)	Drug Delivery Fluorescent Dyes/Probes
DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

Cat. No.	Product Name	Type

HY-Y0873O

PEG35000 Polyethylene glycol 35000	Drug Delivery
PEG35000 is a polyethylene glycol with a molecular weight of 35,000 that can be used as a carrier material and modifier in drug delivery systems .

HY-W440916

DSPE-PEG-FITC (MW 3400)	Drug Delivery Fluorescent Dyes/Probes
DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-144027

Dolichol (13~21)	Drug Delivery
Dolichol (13~21) is a lipid carrier containing isoprene units. Dolichol (13~21) can be used for liposomes applied in drug delivery .

HY-144008

C8 PEG-Ceramide	Drug Delivery
C8 PEG-Ceramide is a lipid product. C8 PEG-Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .

HY-144008A

C8 PEG5000 Ceramide	Drug Delivery
C8 PEG5000 Ceramide is a lipid product. C8 PEG5000 Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .

HY-158209

Block polyoxyethylene-polyoxypropylene	Biochemical Assay Reagents
Block polyoxyethylene-polyoxypropylene is a block copolymer composed of hydrophilic polyoxyethylene (POE) and hydrophobic polyoxypropylene (POP), which can be used to prepare biological materials such as emulsifiers, drug delivery carriers, and stabilizers .

HY-W440915

DSPE-PEG-FITC (MW 2000)	Drug Delivery
DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-W440917

DSPE-PEG-FITC (MW 5000)	Drug Delivery
DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-W763557B

Poly(ethylene glycol) methacrylate (MW 500)	Drug Delivery
Poly(ethylene glycol) methacrylate (MW 500) is a monomethacrylate functionalized PEG, which is used to prepare composite materials, such as Poly(ethylene glycol) methacrylate-chitosan, and can be used as an ocular drug delivery carrier .

HY-W763557A

Poly(ethylene glycol) methacrylate (MW 360)	Drug Delivery
Poly(ethylene glycol) methacrylate (MW 360) is a monomethacrylate functionalized PEG, which is used to prepare composite materials, such as Poly(ethylene glycol) methacrylate-chitosan, and can be used as an ocular drug delivery carrier .

HY-W441009A

DSPE-PEG-Maleimide (MW 3400) ammonium	Drug Delivery
DSPE-PEG-Maleimide (MW 3400) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 3400) ammonium can be used in drug delivery research .

HY-112624B

Dextran T70 (MW 70,000)

Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)

Drug Delivery Thickeners

Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.

HY-112760

18:0 mPEG2000 PE sodium 1 Publications Verification DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium	Drug Delivery
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .

HY-W250313

Polylactic acid

PLA

Biochemical Assay Reagents

Polylactic acid (PLA) is a biodegradable and biocompatible polymer widely used as a carrier for drug delivery systems and a structural material for tissue engineering and medical implants. Polylactic acid acts as a controlled release matrix through the hydrolysis mechanism of ester bonds, gradually releasing the encapsulated drug and metabolizing to non-toxic lactic acid. Polylactic acid has adjustable degradation rate, mechanical properties and the ability to composite with other polymers, and can be used in local or systemic drug delivery, orthopedic fixation devices and 3D printed bone regeneration scaffolds[1][2].

HY-D1005A5

Poloxamer 123 (L43) PEG-PPG-PEG, 1850 (Averag)	Co-solvents
Poloxamer 123 L43 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1850. Poloxamer 123 L43 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A13

Poloxamer 215 (P75) PEG-PPG-PEG, 4150 (Averag)	Co-solvents
Poloxamer 215 P75 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4150. Poloxamer 215 P75 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A20

Poloxamer 334 (P104) PEG-PPG-PEG, 5900 (Averag)	Co-solvents
Poloxamer 334 P104 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 5900. Poloxamer 334 P104 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A11

Poloxamer 185 (P65) PEG-PPG-PEG, 3400 (Averag)	Co-solvents
Poloxamer 185 P65 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 3400. Poloxamer 185 P65 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A7

Poloxamer 125 (L45) PEG-PPG-PEG, 2400 (Averag)	Co-solvents
Poloxamer 125 L45 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2400. Poloxamer 125 L45 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A15

Poloxamer 234 (P84) PEG-PPG-PEG, 4200 (Averag)	Co-solvents
Poloxamer 234 P84 is is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4200. Poloxamer 234 P84 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A12

Poloxamer 212 (L72) PEG-PPG-PEG, 2750 (Averag)	Co-solvents
Poloxamer 212 L72 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2750. Poloxamer 212 L72 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A2

Poloxamer 105 (L35) PEG-PPG-PEG, 1900 (Average)	Co-solvents
Poloxamer 105 L35 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1900 Da. Poloxamer 105 L35 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-112624K

Dextran T5 (MW 5,000)

Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)

Thickeners

Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-112624J

Dextran T4 (MW 4,000)

Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)

Thickeners

Dextran 4,000 is a mucus rheology modifier. The dextran molecules in Dextran 4,000 can reduce the cross-link density of mucus through osmotic effects and hydrogen bond substitution, and reduce viscoelasticity and improve the mucociliary/cough clearance index by destroying the DNA-mucin network structure in mucus. Dextran 4,000 has the ability to improve the rheological properties and clearance ability of cystic fibrosis (CF) sputum, and can be used in the study of inhalation therapy or aerosol delivery of mucostatic respiratory diseases. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-W440903

DSPE-PEG-IA (MW 5000)

Drug Delivery

DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.

HY-W440926

Stearic acid-PEG-NHS (MW 1000)

Drug Delivery

HY-D1005A17

Poloxamer 238 (F88) PEG-PPG-PEG, 11400 (Averag)	Co-solvents
Poloxamer 238 F88 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 11400. Poloxamer 238 F88 reduces the aggregation of red blood cells. Poloxamer 238 F88 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-W440907

DSPE-PEG-Vinylsulfone (MW 5000)	Drug Delivery
DSPE-PEG-Vinylsulfone, MW 5000 is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine. Reagent grade, for research use only.

HY-D1005A9

Poloxamer 183 (L63)

PEG-PPG-PEG, 2650 (Averag)

Co-solvents

Poloxamer 183 L63 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2650. Poloxamer 183 L63 exhibits antimicrobial activity, that inihibits 83% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 183 L63 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A4

Poloxamer 122 (L42)

PEG-PPG-PEG, 1630 (Averag)

Co-solvents

Poloxamer 122 L42 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1630. Poloxamer 122 L42 exhibits antimicrobial activity, that inihibits 56% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 122 L42 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A8

Poloxamer 181 (L61)

PEG-PPG-PEG, 2000 (Averag)

Co-solvents

Poloxamer 181 L61 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2000. Poloxamer 181 L61 exhibits antimicrobial activity, that inihibits 91% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 181 L61 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A19

Poloxamer 333 (P103)

PEG-PPG-PEG, 4950 (Averag)

Co-solvents

Poloxamer 333 P103 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4950. Poloxamer 333 P103 exhibits antimicrobial activity, that inihibits 90% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 333 P103 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-112624E

Dextran T0.8 (MW 800)

Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)

Thickeners

Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-D1005A21

Poloxamer 335 (P105)

PEG-PPG-PEG, 6500 (Averag)

Co-solvents

Poloxamer 335 P105 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 6500. Poloxamer 335 P105 exhibits antimicrobial activity, that inihibits 86% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 334 P104 exhibits muscular toxicity. Poloxamer 334 P104 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-112624I

Dextran T3 (MW 3,000)

Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)

Thickeners

Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-112624H

Dextran T2 (MW 2,000)

Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)

Thickeners

Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM₂), and Isomaltotriose (IM₃). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .

HY-D1005A10

Poloxamer 184 (L64)

PEG-PPG-PEG, 2900 (Averag)

Co-solvents

Poloxamer 184 L64 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2900. Poloxamer 184 L64 exhibts short-term dermal toxicity characterized by slight erythema and intradermal inflammatory response. Poloxamer 184 L64 exhibits antimicrobial activity, that inihibits 60% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 184 L64 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-W583868

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE

1,2-POPE; 16:0-18:1 PE

Drug Delivery

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (H_II) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .

Cat. No.	Product Name	Target	Research Area

HY-P10128

GE11 1 Publications Verification	Biochemical Assay Reagents	Inflammation/Immunology
GE11 is a active peptide and combines with colloidal drug delivery systems as smart carriers for antitumor drugs and can be used for cancer study .

HY-P10502

L57	LDLR	Others
L57 exhibits high affinity to the low-density lipoprotein receptor-related protein 1 (LRP1) with K_i of 45 nM. L57 exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 can be utilized as the carrier for CNS drug delivery .

HY-P4080

MPG peptides, Pα	Peptides	Others
MPG peptides, Pα is an amphipathic carrier peptide that can be used for drug delivery .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-128754

Monoolein	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Interleukin Related TNF Receptor NO Synthase
Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .

HY-128754R

Monoolein (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite Interleukin Related TNF Receptor NO Synthase
Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .

HY-W050154R

Kojic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Parasite Tyrosinase NF-κB CDK
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .

Cat. No.	Product Name		Classification

HY-B2247A

PLGA (75:25) 1 Publications Verification poly(lactic-co-glycolic acid) (75:25)		Polymers
PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .

HY-W440916

DSPE-PEG-FITC (MW 3400)		Pegylated Lipids Fluorescent Lipids
DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-W441009A

DSPE-PEG-Maleimide (MW 3400) ammonium		Pegylated Lipids
DSPE-PEG-Maleimide (MW 3400) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 3400) ammonium can be used in drug delivery research .

HY-112624B

Dextran T70 (MW 70,000) Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)		Polymers
Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.

HY-112760

18:0 mPEG2000 PE sodium 1 Publications Verification DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium		Pegylated Lipids
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .

HY-144027

Dolichol (13~21)		Polymers
Dolichol (13~21) is a lipid carrier containing isoprene units. Dolichol (13~21) can be used for liposomes applied in drug delivery .

HY-144008

C8 PEG-Ceramide		Pegylated Lipids
C8 PEG-Ceramide is a lipid product. C8 PEG-Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .

HY-144008A

C8 PEG5000 Ceramide		Pegylated Lipids
C8 PEG5000 Ceramide is a lipid product. C8 PEG5000 Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .

HY-W440915

DSPE-PEG-FITC (MW 2000)		Pegylated Lipids Fluorescent Lipids
DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-W440917

DSPE-PEG-FITC (MW 5000)		Pegylated Lipids Fluorescent Lipids
DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-N0322B

Cholesterol (Excipient)		Emulsifiers Liposomal Film-forming Agents
Cholesterol Excipient is a component of the cell membrane and a precursor of some hormones, vitamin D and bile acid, with oral activity. Cholesterol Excipient is a drug delivery carrier based on the lipid environment of the cell membrane. Due to its amphiphilicity, good biocompatibility and biodegradability, it can be used as an excipient in drug preparations. Cholesterol Excipient can self-assemble into delivery systems such as micelles, nanoparticles, and liposomes, and achieve controlled drug release by regulating membrane fluidity or responding to the microenvironment. It has the characteristics of high drug loading efficiency and good biocompatibility. Cholesterol Excipient is mainly used for research in the fields of targeted delivery of anticancer, antibacterial, antiviral drugs and treatment of skin diseases. Cholesterol itself is also an endogenous regulator involved in the cleavage of amyloid precursor protein (APP) mediated by β-secretase and intestinal absorption, as well as an endogenous estrogen-related receptor α (ERRα) agonist. Cholesterol affects the subcellular localization of APP processing enzymes by regulating the cell membrane lipid environment, which can promote the production of β-amyloid protein and its adsorption and removal by probiotics. It is used to study the pathogenesis of Alzheimer's disease (AD) and the cholesterol-lowering function of probiotics[1][2][3][4][5].

HY-128754

Monoolein		Emulsifiers
Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .

HY-W583868

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE 1,2-POPE; 16:0-18:1 PE		Phospholipids
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (H_II) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .

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