Search Result
Results for "
cytometry
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-D0950A
-
|
|
DNA Stain
|
Others
|
|
Methyl Green zinc chloride is a potent fluorescent dye. Methyl Green zinc chloride is a DNA stains of cells and electrophoretic gels. Methyl Green zinc chloride can be used as direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm .
|
-
-
- HY-D0988
-
|
|
Fluorescent Dye
Apoptosis
|
Others
|
|
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).
|
-
-
- HY-131008
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescein tyramide is a green fluorescent reagent (λabs: 494 nm; λem: 517 nm). Fluorescein tyramide is widely used for tyramide signal amplification (TSA) with a low-abundance in IHC, ICC, in situ hybridization (FISH) and flow cytometry (FCM) applications .
|
-
-
- HY-15941
-
|
Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
|
Fluorescent Dye
|
Others
|
|
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
|
-
-
- HY-P990169
-
|
|
PD-1/PD-L1
|
Inflammation/Immunology
Cancer
|
|
Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse/human phosphorylated PD-1/CD279. Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12) can detect the phosphorylated form of the PD-1 ITSM by both western blot and flow cytometry .
|
-
-
- HY-D2341
-
|
|
Fluorescent Dye
|
Cancer
|
|
6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .
|
-
-
- HY-P990836
-
|
|
Interleukin Related
|
Inflammation/Immunology
|
|
Anti-IL-9 Antibody (MH9A4) is a kind of mouse IgG2b κ chimeric antibody inhibitor, targeting to human IL-9. Anti-IL-9 Antibody (MH9A4) reacts with human IL-9 (interleukin-9) and does not block the binding of IL-9 to the IL-9 receptor. Anti-IL-9 Antibody (MH9A4) can be used for the detection of flow cytometry and ELISA .
|
-
-
- HY-P990274
-
|
|
Transmembrane Glycoprotein
|
Others
|
|
Anti-Canine CD34 Antibody (1H6) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to canine CD34. Anti-Canine CD34 Antibody (1H6) reacts with canine CD34. Anti-Canine CD34 Antibody (1H6) can be used for the separation and identification of CD34 + cells. Anti-Canine CD34 Antibody (1H6) can be used for detections of western blot, immunohistochemistry and flow cytometry .
|
-
-
- HY-P990810
-
|
|
Arenavirus
|
Infection
|
|
Anti-LCMV Nucleoprotein Antibody (VL-4) is rat-derived IgG2a κ type antibody inhibitor, targeting to LCMV nucleoprotein. Anti-LCMV Nucleoprotein Antibody (VL-4) reacts with lymphocytic choriomeningitis virus (LCMV) nucleoprotein. Anti-LCMV Nucleoprotein Antibody (VL-4) stain LCMV-infected cell internally with no surface staining. Anti-LCMV Nucleoprotein Antibody (VL-4) can be used for the detections of immunofluorescence and flow cytometry in LCMV infection .
|
-
-
- HY-P990816
-
|
|
SARS-CoV
|
Infection
|
|
Anti-SARS-CoV-2 S protein Antibody (NTD, SARS2-29) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to SARS-CoV-2 S protein. Anti-SARS-CoV-2 S protein Antibody (NTD, SARS2-29) reacts with the N-terminal domain (NTD) in the spike (S) protein of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). Anti-SARS-CoV-2 S protein Antibody (NTD, SARS2-29) can be used for the detections of flow cytometry and ELISA in SARS-CoV-2 infection .
|
-
-
- HY-P990847
-
|
|
E-Selectin
|
Inflammation/Immunology
|
|
Anti-E-Selectin Antibody (CL2) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human E-Selectin. Anti-E-Selectin Antibody (CL2) reacts with human E-selectin also known as CD62E, endothelial-leukocyte adhesion molecule 1 (ELAM-1), and leukocyte-endothelial cell adhesion molecule 2 (LECAM2). Anti-E-Selectin Antibody (CL2) directly blocks the binding of E selectin to carbohydrate ligands. Anti-E-Selectin Antibody (CL2) can be used for the detection of flow cytometry .
|
-
-
- HY-P990246
-
|
|
Adhesion G Protein-coupled Receptors (AGPCRs)
|
Inflammation/Immunology
|
|
Anti-Mouse F4/80 Antibody (CI:A3-1) is an anti-mouse F4/80 IgG2b monoclonal antibody. Anti-Mouse F4/80 Antibody (CI:A3-1) can clear macrophages. Anti-Mouse F4/80 Antibody (CI:A3-1) can be used for research on inflammation conditions such as endometriosis. Anti-Mouse F4/80 Antibody (CI:A3-1) often used for flow cytometry analysis and immunohistochemical analysis .
|
-
-
- HY-P990002
-
|
|
c-Kit
|
Inflammation/Immunology
Cancer
|
|
Anti-Mouse CD117/c-Kit Antibody (2B8) is an IgG2b antibody, targeting to mouse CD117/c-Kit. Anti-Mouse CD117/c-Kit Antibody (2B8) reacts with mouse c-Kit (also known as CD117), which is expressed on hematopoietic progenitor cells, mast cells, and acute myeloid leukemia (AML) cells. Anti-Mouse CD117/c-Kit Antibody (2B8) can be used for the detection of flow cytometry, immunofluorescence and immunohistochemistry in cancer and inflammation .
|
-
-
- HY-P990826
-
|
|
YB-1
|
Others
|
|
Anti-YB-1 Antibody (21A3) is a mouse-derived IgG1 chimeric antibody inhibitor, targeting to human YB-1. Anti-YB-1 Antibody (21A3) reacts with human Y-box binding protein 1 (YB-1). Anti-YB-1 Antibody (21A3) can be used for the detections of immunohistochemistry, western blot and flow cytometry .
|
-
-
- HY-P990856
-
|
|
Transferrin Receptor
|
Cancer
|
|
Anti-CD71 Antibody (OKT-9) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD71. Anti-CD71 Antibody (OKT-9) can recognize CD71 also known as Transferrin receptor protein 1 (TfR1). Anti-CD71 Antibody (OKT-9) can be used for the detections of immunohistochemistry, immunofluorescence and flow cytometry in cancer, such as leukemia and lymphoma .
|
-
-
- HY-P990190
-
|
|
MHC
|
Others
|
|
Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) is a mouse-derived IgG2b κ type antibody inhibitor, targeting to Swine MHC Class I. Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) reacts with the swine leucocyte antigen (SLA) class I. Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) can be used for the research of flow cytometry experiments .
|
-
-
- HY-P990303
-
|
|
Nuclear Factor of activated T Cells (NFAT)
|
Others
|
|
Anti-Mouse 2C TCR Antibody (1B2) is a mouse-derived IgG1 type antibody inhibitor, targeting to mouse 2C TCR. Anti-Mouse 2C TCR Antibody (1B2) recognizes determinants on the variable regions of both the α and β subunits of the TCR (T cell receptor) expressed by the mouse cytotoxic T lymphocyte clone 2C. Anti-Mouse 2C TCR Antibody (1B2) can be used for the detections of immunofluorescence and flow cytometry .
|
-
-
- HY-D0163
-
|
|
DNA Stain
|
Others
|
|
Methyl Green is a non-intercalating fluorescent labeling agent that selectively binds to the major groove of DNA. Methyl Green electrostatically interacts with the major groove of DNA through positively charged groups, exhibiting key activities such as high affinity, resistance to photobleaching, and stable fluorescence emission. Methyl Green can be directly measured by microscopy and flow cytometry, with peaks at 633 and 677 nm. Methyl Green can be used for fluorescent labeling of the nuclei of embryonic tissues or cells, or DNA staining and cell activity detection in gel electrophoresis[1][2][3].
|
-
-
- HY-P990870
-
|
|
CD19
IFNAR
Interleukin Related
|
Inflammation/Immunology
|
|
Anti-CD19 Antibody (4G7) is an anti-human CD19 IgG1 monoclonal antibody. Anti-CD19 Antibody (4G7) reduces the killing effect of CAR T cells on Raji cells. Anti-CD19 Antibody (4G7) can be used for research on immunology. Anti-CD19 Antibody (4G7) is often used in flow cytometry. The recommend isotype control of Anti-CD19 Antibody (4G7): Mouse IgG1 kappa, Isotype Control (HY-P99977) .
|
-
-
- HY-P990142
-
|
|
MHC
|
Infection
Inflammation/Immunology
|
|
Anti-Mouse Vβ4 TCR Antibody (KT4) is an anti-mouse Vβ4 TCR IgG2b monoclonal antibody. Anti-Mouse Vβ4 TCR Antibody (KT4) can reduce the proportion of Vβ4 + T cells without affecting their function. Anti-Mouse Vβ4 TCR Antibody (KT4) can be used for research on immunology and infection conditions such as virus infection. Anti-Mouse Vβ4 TCR Antibody (KT4) is often used in flow cytometry .
|
-
-
- HY-P990141
-
|
|
MHC
|
Inflammation/Immunology
|
|
Anti-Mouse Vβ8 TCR Antibody (F23.1) is an anti-mouse Vβ8 TCR IgG2a monoclonal antibody. Anti-Mouse Vβ8 TCR Antibody (F23.1) can clear Vβ8 + T cells to alleviate immune conditions. Anti-Mouse Vβ8 TCR Antibody (F23.1) can be used for research on autoimmune conditions. Anti-Mouse Vβ8 TCR Antibody (F23.1) is often used in flow cytometry .
|
-
-
- HY-D2438
-
|
|
Fluorescent Dye
|
Cancer
|
|
CDDP-PEG-Cy3 is a CDDP-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Cisplatin (CDDP) (HY-17394) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .
|
-
-
- HY-P990198
-
|
|
Galectin
|
Inflammation/Immunology
|
|
Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is a rat-derived anti-mouse/human Mac-2/Galectin-3 IgG2a monoclonal antibody. Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) significantly inhibits IL-6 expression (inhibition rates 34.7% and 55.3%). Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is often used for immunoprecipitation, western blot, immunofluorescence, and flow cytometry .
|
-
-
- HY-158742
-
|
GL13; SBB-A-B
|
Fluorescent Dye
|
Others
|
|
SBB-Analogue (GL13) Biotin (GL13; SBB-A-B) is composed of a Sudan Black B (SBB; HY-D0213) derivative conjugated to biotin. SBB-Analogue (GL13) Biotin detects robustly senescent cells. SBB-Analogue (GL13) Biotin is deprived of the false positive staining disadvantages of SA-β-gal due to serum starvation and cell confluency. SBB-Analogue (GL13) Biotin can be used in flow cytometry and immunofluorescence analysis, etc .
|
-
-
- HY-P990232
-
|
|
IFNAR
|
Others
|
|
Anti-Mouse IFNγRα/CD119 Antibody (2E2) is an Armenian hamster-derived IgG type antibody inhibitor, targeting to mouse IFNγRα/CD119. Anti-Mouse IFNγRα/CD119 Antibody (2E2) reacts with the mouse IFNγR (interferon gamma receptor) α chain also known as CD119 and IFNγ receptor 1. Anti-Mouse IFNγRα/CD119 Antibody (2E2) is a non-neutralizing antibody and does not block the binding of IFNγ to the receptor. Anti-Mouse IFNγRα/CD119 Antibody (2E2) can be used for detections of western blot, flow cytometry and immunoprecipitation .
|
-
-
- HY-P990862
-
|
|
Transmembrane Glycoprotein
|
Cancer
|
|
Anti-CD326/EpCAM Antibody (Ber-EP4) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD326/EpCAM. Anti-CD326/EpCAM Antibody (Ber-EP4) reacts with human CD326 also known as EpCAM (Epithelial Cell Adhesion Molecule). Anti-CD326/EpCAM Antibody (Ber-EP4) is useful to distinguish between cells of mesothelial and epithelial origin. Anti-CD326/EpCAM Antibody (Ber-EP4) can be used for the detections of immunohistochemistry, immunofluorescence and flow cytometry in cancer, such as colon cancer .
|
-
-
- HY-D2435
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
Cancer
|
|
CDDP-PEG-Cy3 is a MTX-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Methotrexate (Amethopterin; MTX) (HY-14519), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .
|
-
-
- HY-P990195
-
|
|
MHC
|
Others
|
|
Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) reacts with the mouse H-2 MHC class I alloantigen (all haplotypes). Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) can be used for the flow cytometry and immunofluorescence experiments .
|
-
-
- HY-D2428
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Infection
Inflammation/Immunology
Cancer
|
|
OVA-PEG-Cy3 is a Cy3 (HY-D0822)-labeled OVA-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Ovalbumins (OVA) (HY-W250978), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .
|
-
-
- HY-P990275
-
|
|
Transmembrane Glycoprotein
|
Cancer
|
|
Anti-Mouse CD326/EpCAM Antibody (G8.8) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD326/EpCAM. Anti-Mouse CD326/EpCAM Antibody (G8.8) reacts with CD326 also known as EpCAM (Epithelial Cell Adhesion Molecule). Anti-Mouse CD326/EpCAM Antibody (G8.8) can be used for cancer research, such as lung carcinoma and colorectal carcinoma. Anti-Mouse CD326/EpCAM Antibody (G8.8) can be used for detections of western blot, immunohistochemistry, immunofluorescence and flow cytometry .
|
-
-
- HY-P990811
-
|
|
Influenza Virus
|
Infection
|
|
Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) is mouse-derived IgG2a κ type antibody inhibitor, targeting to influenza virus nucleoprotein. Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) reacts with influenza virus nucleoprotein (NP). Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) can induce passive immunity to influenza A virus. Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) can be used for the detections of western blot, flow cytometry and immunohistochemistry in Influenza A virus infection .
|
-
-
- HY-66020
-
6-FITC
1 Publications Verification
6-Fluorescein Isothiocyanate
|
Fluorescent Dye
|
Cancer
|
|
6-FITC (6-Fluorescein Isothiocyanate) is a derivative of fluorescein used in wide-ranging applications including flow cytometry.
|
-
-
- HY-159841A
-
|
|
Fluorescent Dye
|
Others
|
|
Filricianine sodium is an hydrophilic fluorochrome. It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
-
-
- HY-D1240
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Rhodamine 101 inner salt is a bright fluorescent dye with excitation and emission maxima at 565 and 595 nm, respectively. It can be used in various biological applications such as fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy, and ELISA.
|
-
-
- HY-N16309
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.
|
-
-
- HY-129547
-
|
|
Fluorescent Dye
|
Others
|
|
Fluo-3 pentapotassium is a fluorescent indicator for intracellular Ca 2+ that is used in flow cytometry and cell-based experiments. Fluo-3 pentapotassium produces fluorescence with an emission maximum at 525 nm upon binding to calcium.
|
-
-
- HY-D2736
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
-
-
- HY-146245F
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
Cancer
|
|
FAM-labeled ODN 1826 sodium, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. FAM-labeled ODN 1826 sodium can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy or flow cytometry.
|
-
-
- HY-172269
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 is a bright, green-fluorescent dye widely used for labeling aldehydes or ketones in polysaccharides or glycoproteins. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
-
- HY-150725B
-
|
|
Toll-like Receptor (TLR)
IFNAR
|
Inflammation/Immunology
|
|
FITC-labeled ODN 1585 (sodium) is a potent inducer of IFN and TNFα production. FITC-labeled ODN 1585 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
-
- HY-150743B
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
FITC-labeled ODN 2395 (sodium), a C class oligodeoxynucleotide, is a TLR9 agonist. FITC-labeled ODN 2395 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
-
- HY-146244B
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. FITC-labeled Agatolimod (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
-
- HY-150724B
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
FITC-labeled ODN 1018 (sodium),an oligodeoxynucleotide, is a TLR-9 agonist. FITC-labeled ODN 1018 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
-
- HY-W090090
-
|
Pyrromethene 546; BDP 493/503 lipid stain
|
Fluorescent Dye
|
Others
|
|
BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
|
-
-
- HY-D2000
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 488 is a hydrophilic rhodamine-based fluorescent dye with strong absorption and high fluorescence quantum yield. ATTO 488 is suitable for flow cytometry (FACS), fluorescence in situ hybridization (FISH) and most other labeling uses (Ex/Em: 500/520 nm) .
|
-
-
- HY-150726B
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
FITC-labeled ODN 1668 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. FITC-labeled ODN 1668 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
-
- HY-146245B
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. FITC-labeled ODN 1826 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
-
- HY-D2760
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 acid is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
-
- HY-150738B
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
FITC-labeled ODN 2088 (sodium) is a potent TLR3, TLR7 and TLR9 inhibitor. FITC-labeled ODN 2088 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
-
- HY-W440911
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Cy5, MW 2000 a red fluorophore polyPEG with lipid hydrophobic tails. The Cy5 fluorophore is commonly used in applications such as protein and nucleic acid labeling for imaging, flow cytometry, and genomic applications. The dye has an excitation peak at 651 nm and an emission peak at 670 nm.
|
-
- HY-D2760A
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 acid triTEA is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-150751B
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
FITC-labeled ODN TTAGGG (sodium), a inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. FITC-labeled ODN TTAGGG (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-D2434
-
|
|
Fluorescent Dye
|
Others
|
|
HRP-PEG-Cy3 is a HRP and Cy3 (HY-D0822) labeled PEG. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm.
|
-
- HY-150741B
-
|
|
Toll-like Receptor (TLR)
Interleukin Related
|
Inflammation/Immunology
|
|
FITC-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. FITC-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-D0090
-
|
|
Fluorescent Dye
|
Others
|
|
MQAE is a chloride ion (Cl -) fluorescent probe that can be used to measure chloride concentrations. The fluorescence intensity of MQAE decreases proportionally as Cl - ions increase. MQAE has high cell permeability and is suitable for fluorescence detection such as confocal microscopy and flow cytometry (Ex/Em=350/460 nm) .
|
-
- HY-D1883B
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5-COOH bromide, a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH bromide can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-W440908
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Cy3, MW 2000 is a fluorophore attached PEG lipid. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The dye has an absorption wavelength that peaks around 548-552 nm, and an emission maximum around 562-570 nm.
|
-
- HY-D1883
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5-COOH (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-D0721
-
|
6-Carboxyfluorescein diacetate
|
Fluorescent Dye
|
Others
|
|
6-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
|
-
- HY-D0025
-
|
|
Fluorescent Dye
|
Others
|
|
7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm) .
|
-
- HY-P4900
-
|
|
Caspase
|
Others
|
|
Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy .
|
-
- HY-D2012
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 488 iodacetamid is a fluorescent dye suitable for single molecule detection applications and high-resolution microscopy for use in flow cytometry (FACS), fluorescence in situ hybridization (FISH) experiments. ATTO 488 iodacetamid has an effective excitation wavelength of 480-515 nm. When using an argon ion laser, the excitation wavelength is recommended to be 488 nm.
|
-
- HY-D1883A
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5-COOH TEA (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH TEA can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-D2761
-
|
|
Fluorescent Dye
|
Others
|
|
DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.
|
-
- HY-N16316
-
|
|
Fluorescent Dye
|
Others
|
|
Meso-Cl cyanine 7 free acid chloride is a Meso-Cl cyanine fluorescent dye. Meso-Cl cyanine 7 free acid chloride can be used for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry (Ex/Em = 778/805 nm) .
|
-
- HY-N16307
-
|
|
Fluorescent Dye
|
Others
|
|
Meso-Cl cyanine 7.5 free acid chloride is a Meso-Cl cyanine fluorescent dye. Meso-Cl cyanine 7.5 free acid chloride can be used for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry (Ex/Em = 815/825 nm) .
|
-
- HY-164190
-
|
|
DNA/RNA Synthesis
|
Others
|
|
m7(3'Ma-Biotin)Gppp(2'OMe)ApG ammonium is a Biotin-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Biotin by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-D2459
-
|
|
Fluorescent Dye
|
Cancer
|
|
Alexa Fluor 430 NHS ester is a compound that couples green fluorescent dye Alexa Fluor 430 to a protein or antibody. Alexa Fluor 430 is used for the generation of stable signals in imaging and flow cytometry. NHS ester can be used to label proteins, amine-modified oligonucleotides and other primary amines (R-NH2) containing amine molecules .
|
-
- HY-D2440
-
|
|
Fluorescent Dye
|
Others
|
|
cRGD-PEG-Cy3 is a Cy3 (HY-D0822) labeled cRGD-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. cRGD can be used to modify lipid for improved stability .
|
-
- HY-D2443
-
|
|
Fluorescent Dye
|
Cancer
|
|
AF594 DBCO is a fluorescent labeling reagent that combines AF594 red fluorescent dye and DBCO (dibenzocyclooctyne). DBCO is a commonly used chemical biomarker group. AF594 DBCO (Excitation wavelength about 590 nm, emission wavelength about 617 nm) can be used to label proteins, cells and other biomolecules for fluorescence imaging and flow cytometry detection .
|
-
- HY-D1020
-
-
- HY-164191
-
|
|
DNA/RNA Synthesis
|
Others
|
|
m7(3'Ma-Peg5-FAM)Gppp(2'OMe)ApG ammonium is a FAM-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of FAM by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-D2437
-
|
|
Fluorescent Dye
Antibiotic
|
Cardiovascular Disease
Cancer
|
|
DOX-PEG-Cy3 (Doxorubicin-PEG-Cy3) is a Cy3 (HY-D0822) labeled DOX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. DOX is a broad-spectrum anthracycline antibiotic with cytotoxic properties .
|
-
- HY-153232
-
|
|
Fluorescent Dye
Liposome
|
Others
|
|
eGFP circRNA-LNP is a lipid nanoparticle (LNP) containing eGFP circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
|
-
- HY-126821
-
|
|
Fluorescent Dye
|
Others
|
|
Fluo-3 and related molecule Fluo3/AM are used as a fluorescence indicator of intracellular calcium (Ca 2+). Fluo-3 may be use for flow cytometry and confocal laser scanning microscopy using visible light excitation (compatible with argon laser sources operating at 488 nm). Fluorescence intensity increases about 40-fold after calcium binding.
|
-
- HY-D2706
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 3000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2712
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 500000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2708
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 10000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2710
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 40000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2709
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 20000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2707
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-164189
-
|
|
DNA/RNA Synthesis
|
Others
|
|
m7(3'Ma-Cy3)Gppp(2'OMe)ApG ammonium is a Cy3-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Cy3 by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-D2705
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 2000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2711
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 100000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2431
-
|
|
Fluorescent Dye
|
Others
|
|
Galactose-PEG-Cy3 is a Cy3 (HY-D0822) labeled Galactose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Galactose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
|
-
- HY-164188
-
|
|
DNA/RNA Synthesis
|
Others
|
|
m7(3'Ma-Cy5)Gppp(2'OMe)ApG ammonium is a Cy5-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Cy5 by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-D2430
-
|
|
Fluorescent Dye
Bacterial
Fungal
|
Infection
Cancer
|
|
Chitosan-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, Chitosan and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Chitosan exhibits antimicrobial activity against various bacteria and fungi .
|
-
- HY-164187
-
|
|
DNA/RNA Synthesis
|
Others
|
|
m7(3'Ma-Cy7)Gppp(2'OMe)ApG ammonium is a Cy7-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Cy7 by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-D0722
-
|
5-(6)-Carboxyfluorescein diacetate; CFDA
|
Fluorescent Dye
|
Others
|
|
5(6)-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
|
-
- HY-D2433
-
|
|
Fluorescent Dye
|
Others
|
|
Glucose-PEG2000-Cy3 is a Cy3 (HY-D0822) labeled Glucose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Glucose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
|
-
- HY-P11110
-
|
|
PD-1/PD-L1
|
Cancer
|
|
RK-10 is a PD-L1 binding peptide. RK-10 conjugated with Cy5 (HY-D0821) or Biotin (HY-B0511) can used to detect PD-L1 expressing tumors with flow cytometry or immunohistochemistry. RK-10 can be used for cancers like NSCLC, breast cancer, squamous cell carcinoma and melanoma detection research .
|
-
- HY-D2601
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG NH2 (MW 3400) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 3400) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
-
- HY-D2600
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG NH2 (MW 2000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 2000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
-
- HY-D2602
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG NH2 (MW 5000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 5000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
-
- HY-D2441
-
|
|
Fluorescent Dye
|
Cancer
|
|
TAT-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, Cell membrane penetrating peptide (TAT) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. TAT-PEG-Cy3 can be used for cell targeted delivery and biological imaging .
|
-
- HY-D2599
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG NH2 (MW 1000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 1000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
-
- HY-D2466
-
|
|
Fluorescent Dye
|
Infection
Cardiovascular Disease
Cancer
|
|
Dextran-CY3 is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
-
- HY-W800695
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 405 DBCO is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 DBCO reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures.
|
-
- HY-111330
-
|
HPF; 3'-p-(Hydroxyphenyl) fluorescein
|
Fluorescent Dye
Reactive Oxygen Species (ROS)
|
Others
|
|
Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
|
-
- HY-D2603
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG NH2 (MW 10000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 10000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
-
- HY-D2588
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 PEG-NH2 is a polyethylene glycol derivative containing CY7.5 (HY-D0926) fluorescent dye and polyethylene glycol (PEG) and an amino group. The CY7.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy7.5 PEG-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
-
- HY-W800680
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
- HY-W781921
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 Alkyne is a popular labeling dye used in Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
- HY-P990850
-
|
|
c-Myc
|
Cancer
|
|
Anti-c-myc Antibody (9E10) is a kind of mouse IgG1 chimeric antibody, targeting to human c-myc. Anti-c-myc Antibody (9E10) reacts with human c-myc, which is over-expressing in several types of human cancers including lung, breast and colon carcinomas. Anti-c-myc Antibody (9E10) can be can be used for the detections of western blot, ELISA, immunoprecipitation and flow cytometry .
|
-
- HY-153231
-
|
|
mRNA
Fluorescent Dye
Liposome
|
Others
|
eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .
|
-
- HY-153231A
-
|
|
Fluorescent Dye
Liposome
|
Others
|
|
eGFP mRNA-LNP (500 ng/μL) is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .
|
-
- HY-D2426
-
|
|
Fluorescent Dye
Transferrin Receptor
|
Cardiovascular Disease
|
|
Cy3-Transferrin is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Transferrin (HY-P3267). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Transferrin can bind to and mediate the transport of iron .
|
-
- HY-D2436
-
|
|
Fluorescent Dye
Microtubule/Tubulin
Apoptosis
|
Cardiovascular Disease
Cancer
|
|
PTX-PEG-Cy3 (Paclitaxel-PEG-Cy3) is a Cy3 (HY-D0822) labeled PTX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. PTX stabilizes tubulin polymerization. PTX can cause both mitotic arrest and apoptotic cell death. PTX also induces autophagy .
|
-
- HY-116215
-
|
|
Fluorescent Dye
|
Others
|
|
2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
|
-
- HY-147861
-
|
|
Topoisomerase
Apoptosis
|
Cancer
|
|
Topoisomerase II inhibitor 11 (compound 3d) is a potent Topoisomerase II inhibitor, with an IC50 of 2.89 μM. Topoisomerase II inhibitor 11 shows 92.46% inhibition on renal cancer cell line A498 with an IC50 of 3.5 μM. Topoisomerase II inhibitor 11 causes cell cycle arrest at the G2/M phase leading to cell proliferation inhibition and pro-apoptotic activity .
|
-
- HY-D2439
-
|
|
Fluorescent Dye
|
Cancer
|
|
RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .
|
-
- HY-D0150A
-
|
|
Fluorescent Dye
|
Others
|
|
(Z)-Thiazole Orange iodide is an asymmetric cyanine dye whose fluorescence highly depends on the local environment.(Z)-Thiazole Orange iodide is essentially dark in solution; however, its fluorescence increases a thousandfold when (Z)-Thiazole Orange iodide is introduced into double-stranded DNA and RNA (dsDNA or dsRNA). The maximum absorption of Thiazole Orange in complex with DNA is 509 nm, and the maximum emission is 532 nm. Thiazole Orange solution is widely used for determining the percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.
|
-
- HY-D2505
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG-NH2 (MW 1000) is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG-NH2 (MW 1000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
-
- HY-D2506
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG-NH2 (MW 3400) is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG-NH2 (MW 3400) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
-
- HY-D2508
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG-NH2 (MW 10000) is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG-NH2 (MW 10000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
-
- HY-D2751
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. BP Fluor 488 dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
- HY-D0815
-
|
|
Fluorescent Dye
DNA/RNA Synthesis
|
Others
|
|
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
|
-
- HY-W800694
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 405 alkyne triTEA is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 alkyne triTEA reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. A probe for copper-less detection (BP Fluor 405 DBCO) is also available for application where the presence of copper is not acceptable.
|
-
- HY-D2507
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG-NH2 (MW 5000) is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG-NH2 (MW 5000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
-
- HY-P99829
-
|
PF-06647020; ABBV-647; h6M24-vc0101
|
Antibody-Drug Conjugates (ADCs)
Microtubule/Tubulin
|
Cancer
|
|
Cofetuzumab pelidotin (PF-06647020) is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101; HY-12522), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research .
|
-
- HY-W800692
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 350 Azide is a blue-fluorescent, azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
BP Fluor 350 is a water-soluble, moderately photostable, blue-fluorescent probe optimally excited by the 350 nm laser line. It is routinely used for generation of stable signal in imaging and flow cytometry. The brightness and photostability of blue dyes are best suited to direct imaging of high-abundance targets.
|
-
- HY-D0938
-
|
CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester
|
Fluorescent Dye
|
Others
|
|
CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus .
CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
|
-
- HY-161283
-
|
|
MAP3K
|
Others
|
|
JT21-25 (compound 9h) is a potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with IC50 of 5.1 nM .
|
-
- HY-D2765
-
|
|
Biochemical Assay Reagents
|
Others
|
|
BP Fluor 405 Cadaverine is a carbonyl-reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Another common application for BP Fluor 405 Cadaverine is cell fixing by treatment with formaldehyde or glutaraldehyde.
BP Fluor 405 is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode.
|
-
- HY-D2554
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-NH2 (MW 5000) is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG-NH2 (MW 5000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
-
- HY-D2553
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-NH2 (MW 200) is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG-NH2 (MW 2000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
-
- HY-D0938Y
-
|
CFSE (solution); 5(6)-Carboxyfluorescein diacetate succinimidyl ester (solution); 5(6)-CFDA N-succinmidyl ester (solution)
|
Fluorescent Dye
|
Others
|
|
CFDA-SE (solution) (CFSE (solution)) is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus .
CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
|
-
- HY-D2552
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-NH2 (MW 1000) is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG-NH2 (MW 1000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
-
- HY-D2555
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-NH2 (MW 10000) is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG-NH2 (MW 10000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
-
- HY-P990849
-
|
|
c-Fms
|
Others
|
|
Anti-CSF1R/CD115 Antibody (2-4A5-4) is a kind of rat IgG1 κ chimeric antibody inhibitor, targeting to human CSF1R/CD115. Anti-CSF1R/CD115 Antibody (2-4A5-4) can neutralize colony stimulating factor 1 receptor (CSF1R), also known as CD115. Anti-CSF1R/CD115 Antibody (2-4A5-4) can be used for the detections of immunohistochemistry, functional assays and flow cytometry .
|
-
- HY-D0917
-
|
|
DNA Stain
|
Cancer
|
|
TO-PRO 1 is a DNA-binding fluorescent dye for non-living cells (Ex/Em=515 nm/531 nm). TO-PRO 1 can intercalate into base pairs of double-stranded DNA and produce stronger fluorescence. TO-PRO 1 is suitable for necrotic cells or late apoptotic cells with damaged cell membranes, showing green fluorescence under fluorescence microscopy or flow cytometry. TO-PRO 1 can be used to distinguish live cells from dead cells and distinguish cell membrane integrity. TO-PRO 1 can be attached to the surface of Feraheme (FH) nanoparticles (NPs) to obtain fluorescent dye-functionalized NPs for drug delivery studies .
|
-
- HY-D2738
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond.
BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
|
-
- HY-D2768
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 430 NHS Ester is a water-soluble, green-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 430 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection.
|
-
- HY-P990854
-
|
|
Transmembrane Glycoprotein
|
Cancer
|
|
Anti-CEACAM1/3/5/6/8 Antibody (6G5j) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CEACAM1/3/5/6/8. Anti-CEACAM1/3/5/6/8 Antibody (6G5j) reacts with an antigen epitope shared by human carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 1, 3, 5, 6, and 8. Anti-CEACAM1/3/5/6/8 Antibody (6G5j) can be used for the detections of western blot, ELISA, immunofluorescence immunohistochemistry and flow cytometry in cancer .
|
-
- HY-D2771
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 405 NHS Ester is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 405 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection. BP Fluor 405 conjugates can also be used for the detection of abundance targets.
|
-
- HY-W800701
-
|
|
Biochemical Assay Reagents
|
Others
|
|
BP Fluor 546 DBCO is an azide-reactive probe that can be used for imaging azide-tagged biomolecules via a copper-free click reaction. The DBCO moiety reacts with azides to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 546 DBCO is an ideal alternative to copper-requiring fluorescent alkynes.
BP Fluor 546 is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 dye conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, which are often used for generating stable signals in imaging and flow cytometry.
|
-
- HY-D2763
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
|
-
- HY-150175
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O2 •−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O2 •−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O2 •− roles in inflammation, mitochondrial stress, and other physiological processes .
|
-
- HY-D1809
-
|
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 405-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=405 nm/431 nm.
|
-
- HY-D1805
-
|
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 647-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=650 nm/665 nm.
|
-
- HY-D1808
-
|
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 488-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=490 nm/515 nm.
|
-
- HY-D1804
-
|
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 680-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=680 nm/701 nm.
|
-
- HY-D1807
-
|
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 555-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=555 nm/565 nm.
|
-
- HY-D1806
-
|
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 594-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=590 nm/617 nm.
|
-
- HY-D2745
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection.
BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.
|
-
- HY-D2747
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 405 acid is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The carboxylic acid of BP Fluor 405 is a reagent of choice for the preparation of custom activated esters that often are not commercially available. Examples of such activated esters include sulfo-NHS, TFP (2,3,5,6-Tetrafluorophenol), and STP (4-Sulfo-2,3,5,6-Tetrafluorophenol, Sodium Salt). Another common application for the non-activated carboxylic acid is peptide modification during solid phase synthesis, which usually requires in-situ activation with peptide coupling regents, e.g. HATU. BP Fluor 405 acid is also often used for control experiments, and for calibration.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0950A
-
|
|
DNA Stain
|
|
Methyl Green zinc chloride is a potent fluorescent dye. Methyl Green zinc chloride is a DNA stains of cells and electrophoretic gels. Methyl Green zinc chloride can be used as direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm .
|
-
- HY-D0988
-
|
|
Dyes
|
|
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).
|
-
- HY-15941
-
|
Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
|
Fluorescent Dyes/Probes
|
|
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
|
-
- HY-D0163
-
|
|
DNA Stain
|
|
Methyl Green is a non-intercalating fluorescent labeling agent that selectively binds to the major groove of DNA. Methyl Green electrostatically interacts with the major groove of DNA through positively charged groups, exhibiting key activities such as high affinity, resistance to photobleaching, and stable fluorescence emission. Methyl Green can be directly measured by microscopy and flow cytometry, with peaks at 633 and 677 nm. Methyl Green can be used for fluorescent labeling of the nuclei of embryonic tissues or cells, or DNA staining and cell activity detection in gel electrophoresis[1][2][3].
|
-
- HY-66020
-
6-FITC
1 Publications Verification
6-Fluorescein Isothiocyanate
|
Fluorescent Dyes/Probes
|
|
6-FITC (6-Fluorescein Isothiocyanate) is a derivative of fluorescein used in wide-ranging applications including flow cytometry.
|
-
- HY-D1240
-
|
|
Dyes
|
|
Rhodamine 101 inner salt is a bright fluorescent dye with excitation and emission maxima at 565 and 595 nm, respectively. It can be used in various biological applications such as fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy, and ELISA.
|
-
- HY-D2341
-
|
|
Fluorescent Dyes/Probes
|
|
6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .
|
-
- HY-D2438
-
|
|
Fluorescent Dyes/Probes
|
|
CDDP-PEG-Cy3 is a CDDP-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Cisplatin (CDDP) (HY-17394) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .
|
-
- HY-D2435
-
|
|
Dyes
|
|
CDDP-PEG-Cy3 is a MTX-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Methotrexate (Amethopterin; MTX) (HY-14519), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .
|
-
- HY-D2428
-
|
|
Fluorescent Dyes/Probes
|
|
OVA-PEG-Cy3 is a Cy3 (HY-D0822)-labeled OVA-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Ovalbumins (OVA) (HY-W250978), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .
|
-
- HY-129547
-
|
|
Fluorescent Dyes/Probes
|
|
Fluo-3 pentapotassium is a fluorescent indicator for intracellular Ca 2+ that is used in flow cytometry and cell-based experiments. Fluo-3 pentapotassium produces fluorescence with an emission maximum at 525 nm upon binding to calcium.
|
-
- HY-D2736
-
|
|
Fluorescent Dyes/Probes
|
|
BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
-
- HY-172269
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 488 is a bright, green-fluorescent dye widely used for labeling aldehydes or ketones in polysaccharides or glycoproteins. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-W090090
-
|
Pyrromethene 546; BDP 493/503 lipid stain
|
Fluorescent Dyes/Probes
|
|
BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
|
-
- HY-D2000
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 488 is a hydrophilic rhodamine-based fluorescent dye with strong absorption and high fluorescence quantum yield. ATTO 488 is suitable for flow cytometry (FACS), fluorescence in situ hybridization (FISH) and most other labeling uses (Ex/Em: 500/520 nm) .
|
-
- HY-D2760
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 488 acid is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-D2760A
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 488 acid triTEA is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-D2434
-
|
|
Fluorescent Dyes/Probes
|
|
HRP-PEG-Cy3 is a HRP and Cy3 (HY-D0822) labeled PEG. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm.
|
-
- HY-D0090
-
|
|
Fluorescent Dyes/Probes
|
|
MQAE is a chloride ion (Cl -) fluorescent probe that can be used to measure chloride concentrations. The fluorescence intensity of MQAE decreases proportionally as Cl - ions increase. MQAE has high cell permeability and is suitable for fluorescence detection such as confocal microscopy and flow cytometry (Ex/Em=350/460 nm) .
|
-
- HY-D1883B
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5-COOH bromide, a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH bromide can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-D1883
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5-COOH (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-D0721
-
|
6-Carboxyfluorescein diacetate
|
Fluorescent Dyes/Probes
|
|
6-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
|
-
- HY-D0025
-
|
|
Fluorescent Dyes/Probes
|
|
7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm) .
|
-
- HY-D2012
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 488 iodacetamid is a fluorescent dye suitable for single molecule detection applications and high-resolution microscopy for use in flow cytometry (FACS), fluorescence in situ hybridization (FISH) experiments. ATTO 488 iodacetamid has an effective excitation wavelength of 480-515 nm. When using an argon ion laser, the excitation wavelength is recommended to be 488 nm.
|
-
- HY-D1883A
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5-COOH TEA (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH TEA can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-D2761
-
|
|
Fluorescent Dyes/Probes
|
|
DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.
|
-
- HY-D2459
-
|
|
Dyes
|
|
Alexa Fluor 430 NHS ester is a compound that couples green fluorescent dye Alexa Fluor 430 to a protein or antibody. Alexa Fluor 430 is used for the generation of stable signals in imaging and flow cytometry. NHS ester can be used to label proteins, amine-modified oligonucleotides and other primary amines (R-NH2) containing amine molecules .
|
-
- HY-D2440
-
|
|
Fluorescent Dyes/Probes
|
|
cRGD-PEG-Cy3 is a Cy3 (HY-D0822) labeled cRGD-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. cRGD can be used to modify lipid for improved stability .
|
-
- HY-D2443
-
|
|
Dyes
|
|
AF594 DBCO is a fluorescent labeling reagent that combines AF594 red fluorescent dye and DBCO (dibenzocyclooctyne). DBCO is a commonly used chemical biomarker group. AF594 DBCO (Excitation wavelength about 590 nm, emission wavelength about 617 nm) can be used to label proteins, cells and other biomolecules for fluorescence imaging and flow cytometry detection .
|
-
- HY-D1020
-
|
7-AAD
|
DNA Stain
|
|
7-Aminoactinomycin D (7-AAD) a fluorescent DNA stain, is a potent RNA polymerase inhibitor. 7-Aminoactinomycin D selectively binds to GC regions of the DNA. 7-Aminoactinomycin D also has antibacterial effects .
|
-
- HY-D2437
-
|
|
Fluorescent Dyes/Probes
|
|
DOX-PEG-Cy3 (Doxorubicin-PEG-Cy3) is a Cy3 (HY-D0822) labeled DOX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. DOX is a broad-spectrum anthracycline antibiotic with cytotoxic properties .
|
-
- HY-126821
-
|
|
Fluorescent Dyes/Probes
|
|
Fluo-3 and related molecule Fluo3/AM are used as a fluorescence indicator of intracellular calcium (Ca 2+). Fluo-3 may be use for flow cytometry and confocal laser scanning microscopy using visible light excitation (compatible with argon laser sources operating at 488 nm). Fluorescence intensity increases about 40-fold after calcium binding.
|
-
- HY-D2706
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 Dextran (MW 3000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2712
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 Dextran (MW 500000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2708
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 Dextran (MW 10000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2710
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 Dextran (MW 40000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2709
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 Dextran (MW 20000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2707
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 Dextran (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2705
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 Dextran (MW 2000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2711
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 Dextran (MW 100000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2431
-
|
|
Fluorescent Dyes/Probes
|
|
Galactose-PEG-Cy3 is a Cy3 (HY-D0822) labeled Galactose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Galactose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
|
-
- HY-D2430
-
|
|
Fluorescent Dyes/Probes
|
|
Chitosan-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, Chitosan and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Chitosan exhibits antimicrobial activity against various bacteria and fungi .
|
-
- HY-D0722
-
|
5-(6)-Carboxyfluorescein diacetate; CFDA
|
Fluorescent Dyes/Probes
|
|
5(6)-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
|
-
- HY-D2433
-
|
|
Fluorescent Dyes/Probes
|
|
Glucose-PEG2000-Cy3 is a Cy3 (HY-D0822) labeled Glucose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Glucose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
|
-
- HY-D2601
-
|
|
Fluorescent Dyes/Probes
|
|
ICG PEG NH2 (MW 3400) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 3400) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
-
- HY-D2600
-
|
|
Fluorescent Dyes/Probes
|
|
ICG PEG NH2 (MW 2000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 2000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
-
- HY-D2602
-
|
|
Fluorescent Dyes/Probes
|
|
ICG PEG NH2 (MW 5000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 5000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
-
- HY-D2441
-
|
|
Fluorescent Dyes/Probes
|
|
TAT-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, Cell membrane penetrating peptide (TAT) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. TAT-PEG-Cy3 can be used for cell targeted delivery and biological imaging .
|
-
- HY-D2599
-
|
|
Fluorescent Dyes/Probes
|
|
ICG PEG NH2 (MW 1000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 1000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
-
- HY-D2466
-
|
|
Dyes
|
|
Dextran-CY3 is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
- HY-W800695
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 405 DBCO is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 DBCO reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures.
|
- HY-111330
-
|
HPF; 3'-p-(Hydroxyphenyl) fluorescein
|
Fluorescent Dyes/Probes
|
|
Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
|
- HY-D2603
-
|
|
Fluorescent Dyes/Probes
|
|
ICG PEG NH2 (MW 10000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 10000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
|
- HY-D2588
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5 PEG-NH2 is a polyethylene glycol derivative containing CY7.5 (HY-D0926) fluorescent dye and polyethylene glycol (PEG) and an amino group. The CY7.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy7.5 PEG-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
- HY-W800680
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
- HY-D2426
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-Transferrin is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Transferrin (HY-P3267). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Transferrin can bind to and mediate the transport of iron .
|
- HY-D2436
-
|
|
Fluorescent Dyes/Probes
|
|
PTX-PEG-Cy3 (Paclitaxel-PEG-Cy3) is a Cy3 (HY-D0822) labeled PTX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. PTX stabilizes tubulin polymerization. PTX can cause both mitotic arrest and apoptotic cell death. PTX also induces autophagy .
|
- HY-116215
-
|
|
Fluorescent Dyes/Probes
|
|
2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
|
- HY-D2439
-
|
|
Fluorescent Dyes/Probes
|
|
RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .
|
- HY-D0150A
-
|
|
Fluorescent Dyes/Probes
|
|
(Z)-Thiazole Orange iodide is an asymmetric cyanine dye whose fluorescence highly depends on the local environment.(Z)-Thiazole Orange iodide is essentially dark in solution; however, its fluorescence increases a thousandfold when (Z)-Thiazole Orange iodide is introduced into double-stranded DNA and RNA (dsDNA or dsRNA). The maximum absorption of Thiazole Orange in complex with DNA is 509 nm, and the maximum emission is 532 nm. Thiazole Orange solution is widely used for determining the percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.
|
- HY-D2505
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-NH2 (MW 1000) is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG-NH2 (MW 1000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
- HY-D2506
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-NH2 (MW 3400) is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG-NH2 (MW 3400) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
- HY-D2508
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-NH2 (MW 10000) is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG-NH2 (MW 10000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
- HY-D2751
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. BP Fluor 488 dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
- HY-D0815
-
|
|
Fluorescent Dyes/Probes
|
|
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
|
- HY-W800694
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 405 alkyne triTEA is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 alkyne triTEA reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. A probe for copper-less detection (BP Fluor 405 DBCO) is also available for application where the presence of copper is not acceptable.
|
- HY-D2507
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-NH2 (MW 5000) is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG-NH2 (MW 5000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
- HY-W800692
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 350 Azide is a blue-fluorescent, azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
BP Fluor 350 is a water-soluble, moderately photostable, blue-fluorescent probe optimally excited by the 350 nm laser line. It is routinely used for generation of stable signal in imaging and flow cytometry. The brightness and photostability of blue dyes are best suited to direct imaging of high-abundance targets.
|
- HY-D0938
-
|
CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester
|
Fluorescent Dyes/Probes
|
|
CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus .
CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
|
- HY-D2765
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 405 Cadaverine is a carbonyl-reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Another common application for BP Fluor 405 Cadaverine is cell fixing by treatment with formaldehyde or glutaraldehyde.
BP Fluor 405 is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode.
|
- HY-D2554
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-NH2 (MW 5000) is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG-NH2 (MW 5000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
- HY-D2553
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-NH2 (MW 200) is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG-NH2 (MW 2000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
- HY-D0938Y
-
|
CFSE (solution); 5(6)-Carboxyfluorescein diacetate succinimidyl ester (solution); 5(6)-CFDA N-succinmidyl ester (solution)
|
Fluorescent Dyes/Probes
|
|
CFDA-SE (solution) (CFSE (solution)) is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus .
CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
|
- HY-D2552
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-NH2 (MW 1000) is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG-NH2 (MW 1000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
- HY-D2555
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-NH2 (MW 10000) is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG-NH2 (MW 10000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
- HY-D0917
-
|
|
DNA Stain
|
|
TO-PRO 1 is a DNA-binding fluorescent dye for non-living cells (Ex/Em=515 nm/531 nm). TO-PRO 1 can intercalate into base pairs of double-stranded DNA and produce stronger fluorescence. TO-PRO 1 is suitable for necrotic cells or late apoptotic cells with damaged cell membranes, showing green fluorescence under fluorescence microscopy or flow cytometry. TO-PRO 1 can be used to distinguish live cells from dead cells and distinguish cell membrane integrity. TO-PRO 1 can be attached to the surface of Feraheme (FH) nanoparticles (NPs) to obtain fluorescent dye-functionalized NPs for drug delivery studies .
|
- HY-D2738
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond.
BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
|
- HY-D2768
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 430 NHS Ester is a water-soluble, green-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 430 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection.
|
- HY-D2771
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 405 NHS Ester is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 405 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection. BP Fluor 405 conjugates can also be used for the detection of abundance targets.
|
- HY-W800701
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 546 DBCO is an azide-reactive probe that can be used for imaging azide-tagged biomolecules via a copper-free click reaction. The DBCO moiety reacts with azides to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 546 DBCO is an ideal alternative to copper-requiring fluorescent alkynes.
BP Fluor 546 is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 dye conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, which are often used for generating stable signals in imaging and flow cytometry.
|
- HY-D2763
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
|
- HY-D1809
-
|
|
Dyes
|
|
Vari Fluor 405-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=405 nm/431 nm.
|
- HY-D1805
-
|
|
Dyes
|
|
Vari Fluor 647-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=650 nm/665 nm.
|
- HY-D1808
-
|
|
Dyes
|
|
Vari Fluor 488-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=490 nm/515 nm.
|
- HY-D1804
-
|
|
Dyes
|
|
Vari Fluor 680-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=680 nm/701 nm.
|
- HY-D1807
-
|
|
Dyes
|
|
Vari Fluor 555-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=555 nm/565 nm.
|
- HY-D1806
-
|
|
Dyes
|
|
Vari Fluor 594-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=590 nm/617 nm.
|
- HY-D2745
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection.
BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.
|
- HY-D2747
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 405 acid is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The carboxylic acid of BP Fluor 405 is a reagent of choice for the preparation of custom activated esters that often are not commercially available. Examples of such activated esters include sulfo-NHS, TFP (2,3,5,6-Tetrafluorophenol), and STP (4-Sulfo-2,3,5,6-Tetrafluorophenol, Sodium Salt). Another common application for the non-activated carboxylic acid is peptide modification during solid phase synthesis, which usually requires in-situ activation with peptide coupling regents, e.g. HATU. BP Fluor 405 acid is also often used for control experiments, and for calibration.
|
| Cat. No. |
Product Name |
Type |
-
- HY-153232
-
|
|
Drug Delivery
|
|
eGFP circRNA-LNP is a lipid nanoparticle (LNP) containing eGFP circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
|
-
- HY-153231A
-
|
|
Drug Delivery
|
|
eGFP mRNA-LNP (500 ng/μL) is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .
|
-
- HY-W440911
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy5, MW 2000 a red fluorophore polyPEG with lipid hydrophobic tails. The Cy5 fluorophore is commonly used in applications such as protein and nucleic acid labeling for imaging, flow cytometry, and genomic applications. The dye has an excitation peak at 651 nm and an emission peak at 670 nm.
|
-
- HY-W440908
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy3, MW 2000 is a fluorophore attached PEG lipid. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The dye has an absorption wavelength that peaks around 548-552 nm, and an emission maximum around 562-570 nm.
|
-
- HY-153231
-
|
|
Drug Delivery
|
eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4900
-
|
|
Caspase
|
Others
|
|
Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy .
|
-
- HY-P11110
-
|
|
PD-1/PD-L1
|
Cancer
|
|
RK-10 is a PD-L1 binding peptide. RK-10 conjugated with Cy5 (HY-D0821) or Biotin (HY-B0511) can used to detect PD-L1 expressing tumors with flow cytometry or immunohistochemistry. RK-10 can be used for cancers like NSCLC, breast cancer, squamous cell carcinoma and melanoma detection research .
|
-
- HY-K1095
-
|
|
|
MCE Live & Dead Bacterial Viability and Counting Kit is based on dual-fluorescence staining technology, which can effectively differentiate live bacteria from dead bacteria and enable quantitative detection using flow cytometry. It can also be used for quantitative analysis of various bacterial mixtures.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P990169
-
|
|
PD-1/PD-L1
|
Inflammation/Immunology
Cancer
|
|
Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse/human phosphorylated PD-1/CD279. Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12) can detect the phosphorylated form of the PD-1 ITSM by both western blot and flow cytometry .
|
-
- HY-P990246
-
|
|
Adhesion G Protein-coupled Receptors (AGPCRs)
|
Inflammation/Immunology
|
|
Anti-Mouse F4/80 Antibody (CI:A3-1) is an anti-mouse F4/80 IgG2b monoclonal antibody. Anti-Mouse F4/80 Antibody (CI:A3-1) can clear macrophages. Anti-Mouse F4/80 Antibody (CI:A3-1) can be used for research on inflammation conditions such as endometriosis. Anti-Mouse F4/80 Antibody (CI:A3-1) often used for flow cytometry analysis and immunohistochemical analysis .
|
-
- HY-P990002
-
|
|
c-Kit
|
Inflammation/Immunology
Cancer
|
|
Anti-Mouse CD117/c-Kit Antibody (2B8) is an IgG2b antibody, targeting to mouse CD117/c-Kit. Anti-Mouse CD117/c-Kit Antibody (2B8) reacts with mouse c-Kit (also known as CD117), which is expressed on hematopoietic progenitor cells, mast cells, and acute myeloid leukemia (AML) cells. Anti-Mouse CD117/c-Kit Antibody (2B8) can be used for the detection of flow cytometry, immunofluorescence and immunohistochemistry in cancer and inflammation .
|
-
- HY-P990231
-
|
|
Inhibitory Antibodies
|
Others
|
|
Anti-Rat IgG1 Antibody (RG11/39.4) is a mouse-derived IgG2c κ type antibody inhibitor, targeting to rat IgG1. Anti-Rat IgG1 Antibody (RG11/39.4) reacts with the Fc region of rat IgG1. Anti-Rat IgG1 Antibody (RG11/39.4) can be used for detection of flow cytometry .
|
-
- HY-P990230
-
|
|
Inhibitory Antibodies
|
Others
|
|
Anti-Rat IgG2a Antibody (RG7/1.30) is a mouse-derived IgG2b κ type antibody inhibitor, targeting to rat IgG2a. Anti-Rat IgG2a Antibody (RG7/1.30) reacts with the Fc region of rat IgG2a. Anti-Rat IgG2a Antibody (RG7/1.30) can be used for detections of immunofluorescence, flow cytometry and ELISA .
|
-
- HY-P990836
-
|
|
Interleukin Related
|
Inflammation/Immunology
|
|
Anti-IL-9 Antibody (MH9A4) is a kind of mouse IgG2b κ chimeric antibody inhibitor, targeting to human IL-9. Anti-IL-9 Antibody (MH9A4) reacts with human IL-9 (interleukin-9) and does not block the binding of IL-9 to the IL-9 receptor. Anti-IL-9 Antibody (MH9A4) can be used for the detection of flow cytometry and ELISA .
|
-
- HY-P990274
-
|
|
Transmembrane Glycoprotein
|
Others
|
|
Anti-Canine CD34 Antibody (1H6) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to canine CD34. Anti-Canine CD34 Antibody (1H6) reacts with canine CD34. Anti-Canine CD34 Antibody (1H6) can be used for the separation and identification of CD34 + cells. Anti-Canine CD34 Antibody (1H6) can be used for detections of western blot, immunohistochemistry and flow cytometry .
|
-
- HY-P990810
-
|
|
Arenavirus
|
Infection
|
|
Anti-LCMV Nucleoprotein Antibody (VL-4) is rat-derived IgG2a κ type antibody inhibitor, targeting to LCMV nucleoprotein. Anti-LCMV Nucleoprotein Antibody (VL-4) reacts with lymphocytic choriomeningitis virus (LCMV) nucleoprotein. Anti-LCMV Nucleoprotein Antibody (VL-4) stain LCMV-infected cell internally with no surface staining. Anti-LCMV Nucleoprotein Antibody (VL-4) can be used for the detections of immunofluorescence and flow cytometry in LCMV infection .
|
-
- HY-P990816
-
|
|
SARS-CoV
|
Infection
|
|
Anti-SARS-CoV-2 S protein Antibody (NTD, SARS2-29) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to SARS-CoV-2 S protein. Anti-SARS-CoV-2 S protein Antibody (NTD, SARS2-29) reacts with the N-terminal domain (NTD) in the spike (S) protein of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). Anti-SARS-CoV-2 S protein Antibody (NTD, SARS2-29) can be used for the detections of flow cytometry and ELISA in SARS-CoV-2 infection .
|
-
- HY-P990847
-
|
|
E-Selectin
|
Inflammation/Immunology
|
|
Anti-E-Selectin Antibody (CL2) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human E-Selectin. Anti-E-Selectin Antibody (CL2) reacts with human E-selectin also known as CD62E, endothelial-leukocyte adhesion molecule 1 (ELAM-1), and leukocyte-endothelial cell adhesion molecule 2 (LECAM2). Anti-E-Selectin Antibody (CL2) directly blocks the binding of E selectin to carbohydrate ligands. Anti-E-Selectin Antibody (CL2) can be used for the detection of flow cytometry .
|
-
- HY-P990826
-
|
|
YB-1
|
Others
|
|
Anti-YB-1 Antibody (21A3) is a mouse-derived IgG1 chimeric antibody inhibitor, targeting to human YB-1. Anti-YB-1 Antibody (21A3) reacts with human Y-box binding protein 1 (YB-1). Anti-YB-1 Antibody (21A3) can be used for the detections of immunohistochemistry, western blot and flow cytometry .
|
-
- HY-P990856
-
|
|
Transferrin Receptor
|
Cancer
|
|
Anti-CD71 Antibody (OKT-9) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD71. Anti-CD71 Antibody (OKT-9) can recognize CD71 also known as Transferrin receptor protein 1 (TfR1). Anti-CD71 Antibody (OKT-9) can be used for the detections of immunohistochemistry, immunofluorescence and flow cytometry in cancer, such as leukemia and lymphoma .
|
-
- HY-P990190
-
|
|
MHC
|
Others
|
|
Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) is a mouse-derived IgG2b κ type antibody inhibitor, targeting to Swine MHC Class I. Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) reacts with the swine leucocyte antigen (SLA) class I. Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) can be used for the research of flow cytometry experiments .
|
-
- HY-P990303
-
|
|
Nuclear Factor of activated T Cells (NFAT)
|
Others
|
|
Anti-Mouse 2C TCR Antibody (1B2) is a mouse-derived IgG1 type antibody inhibitor, targeting to mouse 2C TCR. Anti-Mouse 2C TCR Antibody (1B2) recognizes determinants on the variable regions of both the α and β subunits of the TCR (T cell receptor) expressed by the mouse cytotoxic T lymphocyte clone 2C. Anti-Mouse 2C TCR Antibody (1B2) can be used for the detections of immunofluorescence and flow cytometry .
|
-
- HY-P990870
-
|
|
CD19
IFNAR
Interleukin Related
|
Inflammation/Immunology
|
|
Anti-CD19 Antibody (4G7) is an anti-human CD19 IgG1 monoclonal antibody. Anti-CD19 Antibody (4G7) reduces the killing effect of CAR T cells on Raji cells. Anti-CD19 Antibody (4G7) can be used for research on immunology. Anti-CD19 Antibody (4G7) is often used in flow cytometry. The recommend isotype control of Anti-CD19 Antibody (4G7): Mouse IgG1 kappa, Isotype Control (HY-P99977) .
|
-
- HY-P990142
-
|
|
MHC
|
Infection
Inflammation/Immunology
|
|
Anti-Mouse Vβ4 TCR Antibody (KT4) is an anti-mouse Vβ4 TCR IgG2b monoclonal antibody. Anti-Mouse Vβ4 TCR Antibody (KT4) can reduce the proportion of Vβ4 + T cells without affecting their function. Anti-Mouse Vβ4 TCR Antibody (KT4) can be used for research on immunology and infection conditions such as virus infection. Anti-Mouse Vβ4 TCR Antibody (KT4) is often used in flow cytometry .
|
-
- HY-P990141
-
|
|
MHC
|
Inflammation/Immunology
|
|
Anti-Mouse Vβ8 TCR Antibody (F23.1) is an anti-mouse Vβ8 TCR IgG2a monoclonal antibody. Anti-Mouse Vβ8 TCR Antibody (F23.1) can clear Vβ8 + T cells to alleviate immune conditions. Anti-Mouse Vβ8 TCR Antibody (F23.1) can be used for research on autoimmune conditions. Anti-Mouse Vβ8 TCR Antibody (F23.1) is often used in flow cytometry .
|
-
- HY-P990872
-
|
|
Inhibitory Antibodies
|
Cancer
|
|
Anti-CA19-9 Antibody (1116-NS-19-9) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CA19-9. Anti-CA19-9 Antibody (1116-NS-19-9) reacts with carbohydrate antigen 19-9 (CA19-9), which is overexpressed in certain cancers, such as gastric and pancreatic cancer. Anti-CA19-9 Antibody (1116-NS-19-9) can be used for the detections of immunohistochemistry, immunofluorescence and flow cytometry .
|
-
- HY-P990198
-
|
|
Galectin
|
Inflammation/Immunology
|
|
Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is a rat-derived anti-mouse/human Mac-2/Galectin-3 IgG2a monoclonal antibody. Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) significantly inhibits IL-6 expression (inhibition rates 34.7% and 55.3%). Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is often used for immunoprecipitation, western blot, immunofluorescence, and flow cytometry .
|
-
- HY-P990232
-
|
|
IFNAR
|
Others
|
|
Anti-Mouse IFNγRα/CD119 Antibody (2E2) is an Armenian hamster-derived IgG type antibody inhibitor, targeting to mouse IFNγRα/CD119. Anti-Mouse IFNγRα/CD119 Antibody (2E2) reacts with the mouse IFNγR (interferon gamma receptor) α chain also known as CD119 and IFNγ receptor 1. Anti-Mouse IFNγRα/CD119 Antibody (2E2) is a non-neutralizing antibody and does not block the binding of IFNγ to the receptor. Anti-Mouse IFNγRα/CD119 Antibody (2E2) can be used for detections of western blot, flow cytometry and immunoprecipitation .
|
-
- HY-P990862
-
|
|
Transmembrane Glycoprotein
|
Cancer
|
|
Anti-CD326/EpCAM Antibody (Ber-EP4) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD326/EpCAM. Anti-CD326/EpCAM Antibody (Ber-EP4) reacts with human CD326 also known as EpCAM (Epithelial Cell Adhesion Molecule). Anti-CD326/EpCAM Antibody (Ber-EP4) is useful to distinguish between cells of mesothelial and epithelial origin. Anti-CD326/EpCAM Antibody (Ber-EP4) can be used for the detections of immunohistochemistry, immunofluorescence and flow cytometry in cancer, such as colon cancer .
|
-
- HY-P990195
-
|
|
MHC
|
Others
|
|
Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) reacts with the mouse H-2 MHC class I alloantigen (all haplotypes). Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) can be used for the flow cytometry and immunofluorescence experiments .
|
-
- HY-P990275
-
|
|
Transmembrane Glycoprotein
|
Cancer
|
|
Anti-Mouse CD326/EpCAM Antibody (G8.8) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD326/EpCAM. Anti-Mouse CD326/EpCAM Antibody (G8.8) reacts with CD326 also known as EpCAM (Epithelial Cell Adhesion Molecule). Anti-Mouse CD326/EpCAM Antibody (G8.8) can be used for cancer research, such as lung carcinoma and colorectal carcinoma. Anti-Mouse CD326/EpCAM Antibody (G8.8) can be used for detections of western blot, immunohistochemistry, immunofluorescence and flow cytometry .
|
-
- HY-P990811
-
|
|
Influenza Virus
|
Infection
|
|
Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) is mouse-derived IgG2a κ type antibody inhibitor, targeting to influenza virus nucleoprotein. Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) reacts with influenza virus nucleoprotein (NP). Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) can induce passive immunity to influenza A virus. Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) can be used for the detections of western blot, flow cytometry and immunohistochemistry in Influenza A virus infection .
|
-
- HY-P990850
-
|
|
c-Myc
|
Cancer
|
|
Anti-c-myc Antibody (9E10) is a kind of mouse IgG1 chimeric antibody, targeting to human c-myc. Anti-c-myc Antibody (9E10) reacts with human c-myc, which is over-expressing in several types of human cancers including lung, breast and colon carcinomas. Anti-c-myc Antibody (9E10) can be can be used for the detections of western blot, ELISA, immunoprecipitation and flow cytometry .
|
-
- HY-P99829
-
|
PF-06647020; ABBV-647; h6M24-vc0101
|
Antibody-Drug Conjugates (ADCs)
Microtubule/Tubulin
|
Cancer
|
|
Cofetuzumab pelidotin (PF-06647020) is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101; HY-12522), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research .
|
-
- HY-P990849
-
|
|
c-Fms
|
Others
|
|
Anti-CSF1R/CD115 Antibody (2-4A5-4) is a kind of rat IgG1 κ chimeric antibody inhibitor, targeting to human CSF1R/CD115. Anti-CSF1R/CD115 Antibody (2-4A5-4) can neutralize colony stimulating factor 1 receptor (CSF1R), also known as CD115. Anti-CSF1R/CD115 Antibody (2-4A5-4) can be used for the detections of immunohistochemistry, functional assays and flow cytometry .
|
-
- HY-P990854
-
|
|
Transmembrane Glycoprotein
|
Cancer
|
|
Anti-CEACAM1/3/5/6/8 Antibody (6G5j) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CEACAM1/3/5/6/8. Anti-CEACAM1/3/5/6/8 Antibody (6G5j) reacts with an antigen epitope shared by human carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 1, 3, 5, 6, and 8. Anti-CEACAM1/3/5/6/8 Antibody (6G5j) can be used for the detections of western blot, ELISA, immunofluorescence immunohistochemistry and flow cytometry in cancer .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N16309
-
|
|
Structural Classification
Lipid
|
Fluorescent Dye
|
|
Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.
|
-
-
- HY-N16316
-
|
|
Structural Classification
Lipid
|
Fluorescent Dye
|
|
Meso-Cl cyanine 7 free acid chloride is a Meso-Cl cyanine fluorescent dye. Meso-Cl cyanine 7 free acid chloride can be used for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry (Ex/Em = 778/805 nm) .
|
-
-
- HY-N16307
-
|
|
Structural Classification
Lipid
|
Fluorescent Dye
|
|
Meso-Cl cyanine 7.5 free acid chloride is a Meso-Cl cyanine fluorescent dye. Meso-Cl cyanine 7.5 free acid chloride can be used for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry (Ex/Em = 815/825 nm) .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-D2443
-
|
|
|
DBCO
|
|
AF594 DBCO is a fluorescent labeling reagent that combines AF594 red fluorescent dye and DBCO (dibenzocyclooctyne). DBCO is a commonly used chemical biomarker group. AF594 DBCO (Excitation wavelength about 590 nm, emission wavelength about 617 nm) can be used to label proteins, cells and other biomolecules for fluorescence imaging and flow cytometry detection .
|
-
- HY-W800694
-
|
|
|
Alkynes
|
|
BP Fluor 405 alkyne triTEA is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 alkyne triTEA reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. A probe for copper-less detection (BP Fluor 405 DBCO) is also available for application where the presence of copper is not acceptable.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-146245F
-
|
|
|
CpG ODNs
|
|
FAM-labeled ODN 1826 sodium, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. FAM-labeled ODN 1826 sodium can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy or flow cytometry.
|
-
- HY-150743B
-
|
|
|
CpG ODNs
|
|
FITC-labeled ODN 2395 (sodium), a C class oligodeoxynucleotide, is a TLR9 agonist. FITC-labeled ODN 2395 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-150724B
-
|
|
|
CpG ODNs
|
|
FITC-labeled ODN 1018 (sodium),an oligodeoxynucleotide, is a TLR-9 agonist. FITC-labeled ODN 1018 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-150725B
-
|
|
|
CpG ODNs
|
|
FITC-labeled ODN 1585 (sodium) is a potent inducer of IFN and TNFα production. FITC-labeled ODN 1585 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-146244B
-
|
|
|
CpG ODNs
|
|
FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. FITC-labeled Agatolimod (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-150726B
-
|
|
|
CpG ODNs
|
|
FITC-labeled ODN 1668 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. FITC-labeled ODN 1668 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-146245B
-
|
|
|
CpG ODNs
|
|
FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. FITC-labeled ODN 1826 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-150738B
-
|
|
|
CpG ODNs
|
|
FITC-labeled ODN 2088 (sodium) is a potent TLR3, TLR7 and TLR9 inhibitor. FITC-labeled ODN 2088 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-W440911
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG-Cy5, MW 2000 a red fluorophore polyPEG with lipid hydrophobic tails. The Cy5 fluorophore is commonly used in applications such as protein and nucleic acid labeling for imaging, flow cytometry, and genomic applications. The dye has an excitation peak at 651 nm and an emission peak at 670 nm.
|
-
- HY-150751B
-
|
|
|
CpG ODNs
|
|
FITC-labeled ODN TTAGGG (sodium), a inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. FITC-labeled ODN TTAGGG (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-150741B
-
|
|
|
CpG ODNs
|
|
FITC-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. FITC-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
|
-
- HY-W440908
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG-Cy3, MW 2000 is a fluorophore attached PEG lipid. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The dye has an absorption wavelength that peaks around 548-552 nm, and an emission maximum around 562-570 nm.
|
-
- HY-164190
-
|
|
|
Cap Analogs
|
|
m7(3'Ma-Biotin)Gppp(2'OMe)ApG ammonium is a Biotin-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Biotin by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-164191
-
|
|
|
Cap Analogs
|
|
m7(3'Ma-Peg5-FAM)Gppp(2'OMe)ApG ammonium is a FAM-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of FAM by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-164189
-
|
|
|
Cap Analogs
|
|
m7(3'Ma-Cy3)Gppp(2'OMe)ApG ammonium is a Cy3-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Cy3 by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-164188
-
|
|
|
Cap Analogs
|
|
m7(3'Ma-Cy5)Gppp(2'OMe)ApG ammonium is a Cy5-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Cy5 by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-164187
-
|
|
|
Cap Analogs
|
|
m7(3'Ma-Cy7)Gppp(2'OMe)ApG ammonium is a Cy7-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Cy7 by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.
|
-
- HY-160050
-
|
|
|
Aptamers
|
|
CD63-1 aptamer sodium is a high-affinity and specific DNA aptamer targeting the CD63 protein (Kd: 38.71 nM). CD63-1 aptamer sodium efficiently binds to CD63-positive cells, including breast cancer MDA-MB-231 cells and CD63-overexpressing HEK293T cells, with moderate binding affinity (Kd~100 nM) as assessed by flow cytometry .
|
-
- HY-153231
-
|
|
|
mRNA
|
eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .
|
-
- HY-160051
-
|
|
|
Aptamers
|
|
CD63-2 aptamer sodium is a high-affinity and specific DNA aptamer targeting the CD63 protein (Kd: 78.43 nM). CD63-1 aptamer sodium efficiently binds to CD63-positive cells, including breast cancer MDA-MB-231 cells and CD63-overexpressing HEK293T cells, with moderate binding affinity (Kd~100 nM) as assessed by flow cytometry .
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
