Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65))

Cat. No.: HY-P990811 Purity: ≥95.0%: Data Sheet
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Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) is mouse-derived IgG2a κ type antibody inhibitor, targeting to influenza virus nucleoprotein. Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) reacts with influenza virus nucleoprotein (NP). Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) can induce passive immunity to influenza A virus. Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) can be used for the detections of western blot, flow cytometry and immunohistochemistry in Influenza A virus infection.

For research use only. We do not sell to patients.

Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) Featured Recommendations:

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Description

Isotype

Mouse IgG2a kappa

Recommend Isotype Controls

Mouse IgG2a kappa, Isotype Control

Species Reactivity

Virus

IC₅₀ & Target

influenza virus nucleoprotein

In Vivo

Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) (350 μg, i.p., at the day of and theday prior to H1N1 infection) shows robust protection from H1N1-induced secondary pneumococcal disease in H1N1-infected mice models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	H1N1-infected mice models^[1]
Dosage:	350 μg
Administration:	Intraperitoneally injection, at the day of and theday prior to H1N1 infection
Result:	Reduced the number of bacteremic mice and levels of bacteremia. Reduced pneumococcal lethality in mice infected previously with influenza.

Application

ELISA, FACS, Functional assay, Research in vivo

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Molecular Weight

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65))]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Purity: ≥95.0%

Select Batch:

Data Sheet (260 KB) SDS (251 KB)

COA (232 KB)

Inhibitory Antibodies User Guide (602 KB)

References

[1]. Haynes L, et al. Immunity to the conserved influenza nucleoprotein reduces susceptibility to secondary bacterial infections. J Immunol. 2012 Nov 15;189(10):4921-9. [Content Brief]

[2]. Dawson AR, et al. Phosphorylation controls RNA binding and transcription by the influenza virus polymerase. PLoS Pathog. 2020 Sep 3;16(9):e1008841. [Content Brief]

Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) Related Classifications

Infection

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65))Influenza VirusInfluenza A virusNucleoproteinH1N1Western blotFlow cytometryImmunohistochemistryInhibitorinhibitorinhibit

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