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Isoforms Recommended:	c-Fos

Results for "

cFos

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Akt (2) Angiotensin-converting Enzyme (ACE) (4) Antibiotic (2) AP-1 (4) Apoptosis (4) Autophagy (2) Bacterial (3) c-Myc (1) Calcium Channel (1) Drug Derivative (1) EGFR (1) Endogenous Metabolite (5) ERK (2) GABA Receptor (1) Insulin Receptor (1) Interleukin Related (1) JNK (2) MEK (1) Mitosis (1) MMP (1) Neuropeptide Y Receptor (1) NF-κB (7) NOD-like Receptor (NLR) (1) Nuclear Factor of activated T Cells (NFAT) (1) p38 MAPK (4) PERK (2) Phosphatase (1) Reactive Oxygen Species (ROS) (1) Reference Standards (3) RIP kinase (1) Small Interfering RNA (siRNA) (3) TNF Receptor (3)
By Research Areas:	Cancer (7) Cardiovascular Disease (5) Endocrinology (1) Infection (5) Inflammation/Immunology (8) Metabolic Disease (3) Neurological Disease (6)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2119

Sciadopitysin 2 Publications Verification	TNF Receptor NF-κB	Inflammation/Immunology
Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba . Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of *c-Fos* and NFATc1 .

HY-A0116A

Trandolaprilate hydrate Trandolaprilat hydrate; RU 44403 hydrate	Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease
Trandolaprilate hydrate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate hydrate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity .

HY-107621

U0124	MEK	Cancer
U0124, an inactive U0126 analog, has no effect on c-Fos and c-Jun protein or mRNA levels. U0126 is a MEK inhibitor. U0124 does not inhibit MEK at concentrations up to 100 μM .

HY-168895

c-Fos-IN-1	AP-1 ERK Apoptosis	Cancer
c-Fos-IN-1 (Compound P16) is a c-Jun inhibitor, and decreases mRNA levels and protein levels of *c-Fos. c-Fos-IN-1 also inhibits the phosphorylation activity of ERK* and the transcriptional activity of AP-1. c-Fos-IN-1 shows anticancer activity by inhibiting ERK/c-Fos/Jun pathway. c-Fos-IN-1 inhibits the proliferation and migration of gastric cancer cells (IC₅₀: 2.31 μM for MGC-803 cell). c-Fos-IN-1 arrests cell cycle at G2/M phase and induces cancer cell apoptosis. c-Fos-IN-1 inhibits gastric cancer tumor growth .

HY-P11321

IUB0271 acyl-GIP	Insulin Receptor	Metabolic Disease
IUB0271 (acyl-GIP) is a fatty acylated and long-acting glucose-dependent insulinotropic polypeptide (GIP). IUB0271 increases cFos neuronal activity in hypothalamic feeding centers and decreases body weight, food intake and glycemia in DIO mouse models, and these effects depend on CNS-GIPR signaling. IUB0271 can be used for type 2 diabetes mellitus (T2DM) and obesity research .

HY-RS16815

Fos Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fos Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fos gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fos Mouse Pre-designed siRNA Set A Fos Mouse Pre-designed siRNA Set A

HY-RS23255

Fos Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fos Rat Pre-designed siRNA Set A contains three designed siRNAs for Fos gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fos Rat Pre-designed siRNA Set A Fos Rat Pre-designed siRNA Set A

HY-120306

HHL-6	AP-1	Neurological Disease
HHL-6 can regulate the overexpression of *c-Fos* and BDNF proteins. HHL-6 has potent anticonvulsant and antiepileptogenic effects .

HY-RS05032

FOS Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FOS Human Pre-designed siRNA Set A contains three designed siRNAs for FOS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FOS Human Pre-designed siRNA Set A FOS Human Pre-designed siRNA Set A

HY-A0116

Trandolaprilate Trandolaprilat; RU 44403	Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease
Trandolaprilate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity .

HY-N11775

Eudebeiolide B Plebeiolide D	NF-κB Akt Nuclear Factor of activated T Cells (NFAT) Phosphatase	Metabolic Disease
Eudebeiolide B is a compound that can be isolated from Salvia plebeia R. Br. Eudebeiolide B inhibits osteoclastogenesis by regulating RANKL-induced NF-κB, c-Fos and calcium signaling. Eudebeiolide B can be used for osteoclast-related diseases research .

HY-A0116S1

Trandolaprilate-d6	Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease
Trandolaprilate-d₆ is the deuterium labeled Trandolaprilate . Trandolaprilate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity .

HY-N2119R

Sciadopitysin (Standard)	TNF Receptor Reference Standards NF-κB	Inflammation/Immunology
Sciadopitysin (Standard) is the analytical standard of Sciadopitysin. This product is intended for research and analytical applications. Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba . Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of c-Fos and NFATc1 .

HY-A0116R

Trandolaprilate (Standard) Trandolaprilat (Standard); RU 44403 (Standard)	Reference Standards Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease
Trandolaprilate (Standard) is the analytical standard of Trandolaprilate. This product is intended for research and analytical applications. Trandolaprilate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity .

HY-N3071

Picrasidine I	Apoptosis Reactive Oxygen Species (ROS)	Inflammation/Immunology
Picrasidine I is an anti-inflammatory and anti-osteoclastogenic dimeric alkaloid that can be isolated from Picrasma quassioides. Picrasidine I inducs cell cycle arrest, and triggers cell apoptosis by downregulats ERK and Akt pathways. Picrasidine I inhibits the activation of MAPKs, NF-κB and ROS generation, and suppresses the expression of c-Fos and NFATc1 .

HY-169451

Cannabidiolic acid methyl ester HU-580	5-HT Receptor	Neurological Disease
Cannabidiolic acid methyl ester (HU-580) is an orally active cannabidiolic acid analogue. Cannabidiolic acid methyl ester can enhance the activation of 5-HT_1A receptor and increase the expression of *c-Fos* and NeuN in specific hypothalamic nuclei of rats. Cannabidiolic acid methyl ester has anti-nausea, anti-anxiety and anti-injury effects .

HY-N0231

Bavachalcone 2 Publications Verification Broussochalcone B	Bacterial Antibiotic NF-κB PERK Akt Autophagy Apoptosis	Infection Neurological Disease Inflammation/Immunology Cancer
Bavachalcone is a potent inducer of apoptosis. Bavachalcone exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells. Bavachalcone acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway. Bavachalcone inhibits osteoclasts by interfering with ERK and Akt signaling pathways and the expression of *c-Fos* and NFATc1. Bavachalcone exhibits a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro .

HY-B1606

Chlorothymol Chlorthymol; 6-Chlorothymol	GABA Receptor Bacterial AP-1	Infection Neurological Disease
Chlothymol is a potent positive modulator of the GABA_A receptor subunit LGC-37, anticonvulsant, and antibacterial agent. Chlothymol inhibits Pentylenetetrazol-induced *c-fos* expression. Chlothymol inhibits the growth of Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA) strains, including LAC, with an MIC of 32 μg/mL. Chlorothymol has protective effects against epileptic seizures in various mouse models .

HY-P10506

CMX-8933	JNK	Neurological Disease
CMX-8933 is an octapeptide fragment of the goldfish brain neurotrophic factor ependymin. CMX-8933 increases the enzymatic activity of c-Jun N-terminal kinase (JNK), increases the phosphorylation of JNK and c-Jun proteins, and increases the cellular levels of c-Jun and c-Fos mRNA. CMX-8933 can be used to study the role of ependymin in neuroplasticity, learning, memory formation, and neural regeneration .

HY-N0231R

Bavachalcone (Standard) Broussochalcone B (Standard)	Reference Standards Bacterial Antibiotic NF-κB PERK Apoptosis Autophagy	Infection Neurological Disease Inflammation/Immunology Cancer
Bavachalcone (Standard) is the analytical standard of Bavachalcone. This product is intended for research and analytical applications. Bavachalcone is a potent inducer of apoptosis. Bavachalcone exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells. Bavachalcone acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway. Bavachalcone inhibits osteoclasts by interfering with ERK and Akt signaling pathways and the expression of *c-Fos* and NFATc1. Bavachalcone exhibits a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro .

HY-131721

14,15-EET-SI	Drug Derivative Mitosis	Others
14,15-EET-SI is a sulfonimide (SI) analog metabolized from 14,15-EET, which is also an effective mitogen. 14,15-EET-SI can stimulate the incorporation of [3H] thymidine, activate pp60c-src and initiate the tyrosine kinase cascade, mediating their mitotic effects. Additionally, 14,15-EET-SI can increase cell proliferation as well as the expression of c-fos and egr-1 mRNA .

HY-P10408

Candidalysin	EGFR MMP Calcium Channel NOD-like Receptor (NLR) ERK p38 MAPK	Infection Inflammation/Immunology
Candidalysin is a cytolytic peptide toxin secreted by the fungus Candida albicans. Candidalysin drives epithelial immune responses by activating the EGFR-MAPK signaling pathway, inducing MMP expression and calcium influx, and regulating the c-Fos transcription factor and MKP1 via p38 MAPK and ERK1/2 respectively. Candidalysin is essential for mucosal and systemic infections, activating NLRP3 to promote inflammatory responses, neutrophil recruitment, and Th17 immunity. Candidalysin activates LDH causing membrane damage and exhibiting cytotoxicity

HY-169021

JNK-1-IN-3	JNK	Cancer
JNK-1-IN-3 (Compound 9e) is an inhibitor of JNK1 that downregulates JNK1 gene expression and inhibits the protein levels of its phosphorylated form, concurrently reducing the expression of its downstream targets, c-Jun and *c-Fos, in tumors while restoring p53* activity. JNK-1-IN-3 exhibits broad-spectrum antiproliferative activity, particularly with high inhibitory activity against renal and breast cancer cell lines, demonstrating both in vivo and in vitro anticancer activity .

HY-P11291

NNC0165-1273	Neuropeptide Y Receptor	Endocrinology
NNC0165-1273 is an analog of gut hormone peptide YY (PYY_3-36). NNC0165-1273 has a superior affinity for Y2 receptor over Y1, Y4, and Y5 receptor. NNC0165-1273 has a potent anorectic effect and significantly reduces nighttime and ghrelin-induced food intake by producing early satiety. NNC0165-1273 inhibits ghrelin-induced cFos expression in NPY/AgRP neurons. NNC0165-1273 can be used for antiobesity therapies research .

HY-168482

NF-κB/MAPK-IN-2	NF-κB p38 MAPK	Cancer
NF-κB/MAPK-IN-2 (compound 14) is a potent NF-κB and MAPK Inhibitor. NF-κB/MAPK-IN-2 decreases the protein expression of p-p65, p-IκB, p-p38, p-JNK, and p-ERK. NF-κB/MAPK-IN-2 reduces the LPS-induced release of TNF-α and IL-6. NF-κB/MAPK-IN-2 inhibits nuclear translocation of p65 and c-Fos. NF-κB/MAPK-IN-2 has the potential for the research of sepsis .

HY-113443

12(S)-HPETE	AP-1	Metabolic Disease
12(S)-HPETE is a 12-hydroxyeicosatetraenoic acid. 12(S)-HPETE has the function of regulating vascular tone. 12(S)-HPETE induces the expression of c-Fos and c-Jun protein and increases activating protein 1 (AP-1) activity in vascular smooth muscle cells.12(S)-HPETE may play a physiological role in vasomotor regulation through endothelium itself and crosstalk between blood cells and endothelium. 12(S)-HPETE can be used in the study of cerebrovascular tension .

HY-175007

RIPK1-IN-32	RIP kinase NF-κB p38 MAPK TNF Receptor Interleukin Related	Infection Inflammation/Immunology
RIPK1-IN-32 is a RIPK inhibitor with anti-inflammatory activity. RIPK1-IN-32 inhibits nitric oxide (NO) release with an IC₅₀ of 3.26 μM. RIPK1-IN-32 significantly alleviates acute liver injury associated with sepsis through the RIPK1/NF-κB/MAPK pathway, therefore preventing the nuclear translocation of p65 and c-fos, which results in reduced expression of TNF-α and IL-6. RIPK1-IN-32 can be used for the study of acute liver injury and sepsis .

HY-176019

Methylcarbamyl PAF C-8	p38 MAPK c-Myc	Cardiovascular Disease Cancer
Methylcarbamyl PAF C-8 is resistant to the degradation function of platelet-activating factor acetylhydrolase (PAF-AH). It has a half-life of more than 100 minutes in platelet-poor plasma and possesses the activity of inducing platelet aggregation. In NRK-49 cells overexpressing the PAF receptor, Methylcarbamyl PAF C-8 can induce the expression of c-myc and *c-fos, and activate mitogen-activated protein kinase (MAPK*). Additionally, Methylcarbamyl PAF C-8 can induce cell cycle arrest in the G1 phase. Methylcarbamyl PAF C-8 holds promise for research in the fields of cardiovascular diseases and anti-cancer therapy .

HY-15026

ATB 429	Endogenous Metabolite	Inflammation/Immunology
ATB-429, a novel H2S-releasing derivative of mesalamine, demonstrates significant anti-nociceptive and anti-inflammatory effects in models of irritable bowel syndrome (IBS). By releasing hydrogen sulfide (H2S), ATB-429 modulates colorectal distension-induced hypersensitivity in both healthy and postcolitic rats. It attenuates abdominal withdrawal responses and suppresses spinal c-Fos mRNA expression, indicating its potential to alleviate pain associated with gastrointestinal inflammation. Moreover, ATB-429 down-regulates colonic cyclooxygenase-2 and interleukin-1β mRNA expression, effects not observed with mesalamine alone. The mechanism involves ATP-sensitive K+ (KATP) channels, as evidenced by reversal of ATB-429's effects with glibenclamide. These findings suggest ATB-429 could offer therapeutic benefits for managing painful intestinal disorders linked to inflammation .

Cat. No.	Product Name	Target	Research Area

HY-P10506

CMX-8933	JNK	Neurological Disease
CMX-8933 is an octapeptide fragment of the goldfish brain neurotrophic factor ependymin. CMX-8933 increases the enzymatic activity of c-Jun N-terminal kinase (JNK), increases the phosphorylation of JNK and c-Jun proteins, and increases the cellular levels of c-Jun and c-Fos mRNA. CMX-8933 can be used to study the role of ependymin in neuroplasticity, learning, memory formation, and neural regeneration .

HY-P10408

Candidalysin	EGFR MMP Calcium Channel NOD-like Receptor (NLR) ERK p38 MAPK	Infection Inflammation/Immunology
Candidalysin is a cytolytic peptide toxin secreted by the fungus Candida albicans. Candidalysin drives epithelial immune responses by activating the EGFR-MAPK signaling pathway, inducing MMP expression and calcium influx, and regulating the c-Fos transcription factor and MKP1 via p38 MAPK and ERK1/2 respectively. Candidalysin is essential for mucosal and systemic infections, activating NLRP3 to promote inflammatory responses, neutrophil recruitment, and Th17 immunity. Candidalysin activates LDH causing membrane damage and exhibiting cytotoxicity

HY-P11321

IUB0271 acyl-GIP	Insulin Receptor	Metabolic Disease
IUB0271 (acyl-GIP) is a fatty acylated and long-acting glucose-dependent insulinotropic polypeptide (GIP). IUB0271 increases cFos neuronal activity in hypothalamic feeding centers and decreases body weight, food intake and glycemia in DIO mouse models, and these effects depend on CNS-GIPR signaling. IUB0271 can be used for type 2 diabetes mellitus (T2DM) and obesity research .

HY-P11291

NNC0165-1273	Neuropeptide Y Receptor	Endocrinology
NNC0165-1273 is an analog of gut hormone peptide YY (PYY_3-36). NNC0165-1273 has a superior affinity for Y2 receptor over Y1, Y4, and Y5 receptor. NNC0165-1273 has a potent anorectic effect and significantly reduces nighttime and ghrelin-induced food intake by producing early satiety. NNC0165-1273 inhibits ghrelin-induced cFos expression in NPY/AgRP neurons. NNC0165-1273 can be used for antiobesity therapies research .

Sciadopitysin 2 Publications Verification	Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba Inflammation/Immunology Disease Research Fields	TNF Receptor NF-κB
Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba . Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of *c-Fos* and NFATc1 .

Trandolaprilate hydrate Trandolaprilat hydrate; RU 44403 hydrate	Cardiovascular Disease Structural Classification Alkaloids Pyrrole Alkaloids Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Angiotensin-converting Enzyme (ACE) Endogenous Metabolite
Trandolaprilate hydrate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate hydrate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity .

Bavachalcone 2 Publications Verification Broussochalcone B	Infection Structural Classification Chalcones Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields	Bacterial Antibiotic NF-κB PERK Akt Autophagy Apoptosis
Bavachalcone is a potent inducer of apoptosis. Bavachalcone exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells. Bavachalcone acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway. Bavachalcone inhibits osteoclasts by interfering with ERK and Akt signaling pathways and the expression of *c-Fos* and NFATc1. Bavachalcone exhibits a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro .

Trandolaprilate Trandolaprilat; RU 44403	Cardiovascular Disease Structural Classification Alkaloids Pyrrole Alkaloids Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Angiotensin-converting Enzyme (ACE) Endogenous Metabolite
Trandolaprilate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity .

Eudebeiolide B Plebeiolide D	Structural Classification Terpenoids Labiatae Sesquiterpenes Source classification Cassia Plants	NF-κB Akt Nuclear Factor of activated T Cells (NFAT) Phosphatase
Eudebeiolide B is a compound that can be isolated from Salvia plebeia R. Br. Eudebeiolide B inhibits osteoclastogenesis by regulating RANKL-induced NF-κB, c-Fos and calcium signaling. Eudebeiolide B can be used for osteoclast-related diseases research .

Sciadopitysin (Standard)	Structural Classification Flavonoids Ginkgoaceae Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba	TNF Receptor Reference Standards NF-κB
Sciadopitysin (Standard) is the analytical standard of Sciadopitysin. This product is intended for research and analytical applications. Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba . Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of c-Fos and NFATc1 .

Trandolaprilate (Standard) Trandolaprilat (Standard); RU 44403 (Standard)	Structural Classification Alkaloids Pyrrole Alkaloids Source classification Endogenous metabolite	Reference Standards Angiotensin-converting Enzyme (ACE) Endogenous Metabolite
Trandolaprilate (Standard) is the analytical standard of Trandolaprilate. This product is intended for research and analytical applications. Trandolaprilate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity .

Picrasidine I	Simaroubaceae Source classification Plants Quassia amaraL. Indole Alkaloids	Apoptosis Reactive Oxygen Species (ROS)
Picrasidine I is an anti-inflammatory and anti-osteoclastogenic dimeric alkaloid that can be isolated from Picrasma quassioides. Picrasidine I inducs cell cycle arrest, and triggers cell apoptosis by downregulats ERK and Akt pathways. Picrasidine I inhibits the activation of MAPKs, NF-κB and ROS generation, and suppresses the expression of c-Fos and NFATc1 .

Bavachalcone (Standard) Broussochalcone B (Standard)	Structural Classification Chalcones Flavonoids Leguminosae Source classification Phenols Polyphenols Psoralea corylifolia L. Plants	Reference Standards Bacterial Antibiotic NF-κB PERK Apoptosis Autophagy
Bavachalcone (Standard) is the analytical standard of Bavachalcone. This product is intended for research and analytical applications. Bavachalcone is a potent inducer of apoptosis. Bavachalcone exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells. Bavachalcone acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway. Bavachalcone inhibits osteoclasts by interfering with ERK and Akt signaling pathways and the expression of *c-Fos* and NFATc1. Bavachalcone exhibits a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro .

12(S)-HPETE	Microorganisms Source classification	AP-1
12(S)-HPETE is a 12-hydroxyeicosatetraenoic acid. 12(S)-HPETE has the function of regulating vascular tone. 12(S)-HPETE induces the expression of c-Fos and c-Jun protein and increases activating protein 1 (AP-1) activity in vascular smooth muscle cells.12(S)-HPETE may play a physiological role in vasomotor regulation through endothelium itself and crosstalk between blood cells and endothelium. 12(S)-HPETE can be used in the study of cerebrovascular tension .

Cat. No.	Product Name	Chemical Structure

HY-A0116S1

Trandolaprilate-d6
Trandolaprilate-d₆ is the deuterium labeled Trandolaprilate . Trandolaprilate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83898

	c-Fos Antibody (YA3595) p55; AP-1; C-FOS	WB, IHC-P, FC, ELISA	Human
	c-Fos Antibody (YA3595) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to c-Fos.

HY-P80081

	c-Fos Antibody (YA506) 1 Publications Verification	WB, IHC-P, ICC/IF	Human, Rat
	c-Fos Antibody (YA506) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to c-Fos.

HY-P80616

	c-Fos Antibody 3 Publications Verification FOS; G0S7; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	c-Fos Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to c-Fos.

HY-P85738

	c-Fos Antibody (YA5430) FOS; G0S7; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7	WB, ELISA, IF-Tissue	Human, Mouse, Rat
	c-Fos Antibody (YA5430) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to c-Fos.

HY-P86346

	c-Fos Antibody (YA6038) FOS; G0S7; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	c-Fos Antibody (YA6038) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to c-Fos.

HY-P86657

	c-Fos Antibody (YA6349) Cellular oncogene fos; FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus; FOS; FOS protein; G0 G1 switch regulatory protein 7; G0S7; Oncogene FOS; Proto oncogene protein c fos; v fos FBJ murine osteosarcoma viral oncogene homolog; AP-1; p55; FOS_HUMAN; Proto-oncogene c-Fos; G0/G1 switch regulatory protein 7.	FC	Human
	c-Fos Antibody (YA6349) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to c-Fos.

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