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Results for "

bacterial growth

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (104) TGF-β Receptor (1) VEGFR (2) Antibiotic (42) Apoptosis (1) Biochemical Assay Reagents (7) Calcium Channel (2) Carbonic Anhydrase (1) COX (2) Deubiquitinase (2) DNA/RNA Synthesis (17) Endogenous Metabolite (16) Fluorescent Dye (1) Fungal (3) Glyoxalase (GLO) (1) HBV (1) HCV (2) HMG-CoA Reductase (HMGCR) (2) Interleukin Related (2) Isotope-Labeled Compounds (11) MicroRNA (6) Mitochondrial Metabolism (1) Monoamine Oxidase (2) NF-κB (5) NO Synthase (2) NOD-like Receptor (NLR) (2) Nucleoside Antimetabolite/Analog (2) p38 MAPK (1) Parasite (4) PDI (3) Phosphatase (1) Pyroptosis (2) Reference Standards (18) SARS-CoV (1) STING (8) Thymidylate Synthase (1) TNF Receptor (3) Tyrosinase (4)
By Research Areas:	Cancer (30) Cardiovascular Disease (4) Infection (102) Inflammation/Immunology (18) Metabolic Disease (10) Neurological Disease (4)

By Targets:

Bacterial (104)

TGF-β Receptor (1)

VEGFR (2)

Antibiotic (42)

Apoptosis (1)

Biochemical Assay Reagents (7)

Calcium Channel (2)

Carbonic Anhydrase (1)

COX (2)

Deubiquitinase (2)

DNA/RNA Synthesis (17)

Endogenous Metabolite (16)

Fluorescent Dye (1)

Fungal (3)

Glyoxalase (GLO) (1)

HBV (1)

HCV (2)

HMG-CoA Reductase (HMGCR) (2)

Interleukin Related (2)

Isotope-Labeled Compounds (11)

MicroRNA (6)

Mitochondrial Metabolism (1)

Monoamine Oxidase (2)

NF-κB (5)

NO Synthase (2)

NOD-like Receptor (NLR) (2)

Nucleoside Antimetabolite/Analog (2)

p38 MAPK (1)

Parasite (4)

PDI (3)

Phosphatase (1)

Pyroptosis (2)

Reference Standards (18)

SARS-CoV (1)

STING (8)

Thymidylate Synthase (1)

TNF Receptor (3)

Tyrosinase (4)

By Research Areas:

Cancer (30)

Cardiovascular Disease (4)

Infection (102)

Inflammation/Immunology (18)

Metabolic Disease (10)

Neurological Disease (4)

132

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Bacterial FGFR GHR VEGFR TGF-beta/Smad PDGFR TGF-β Receptor GHSR EGFR IGF-1R Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W045071

N-Hexanoyl-DL-homoserine lactone	Bacterial	Infection
N-Hexanoyl-DL-homoserine lactone is a *bacterial* quorum sensing molecule produced in the rhizosphere. N-Hexanoyl-DL-homoserine lactone, a bacterial quorum sensing signal, induces transcriptional changes in Arabidopsis and may contribute to tuning plant growth to the microbial composition of the rhizosphere .

HY-W034067

Silver nitrite	Biochemical Assay Reagents Bacterial	Infection
Silver nitrite is an inorganic compound with the chemical formula AgNO₂. Silver nitrite can inhibit cell division and *bacterial* growth by interfering with protein synthesis .

HY-D1117

NADA-green NADA hydrochloride	Fluorescent Dye	Infection
NADA-green is a fluorescent D-amino acid probe. NADA-green is efficiently incorporated into the peptidoglycan of diverse bacterial species peptidoglycan biosynthesis. NADA-green allows probing of bacterial growth with minimal perturbation .

HY-103658

Myramistin Miramistin	Bacterial	Infection
Myramistin (Miramistin) is an antibacterial agent targeting *bacterial* cell membrane. Myramistin can bind to the negatively charged surface of bacteria through its cationic properties, disrupt the integrity of the bacterial cell membrane, inhibit bacterial metabolism and growth, and induce cell death, thus exerting antibacterial activity .

HY-157374

Beef Heart Infusion	Biochemical Assay Reagents	Others
Beef Heart Infusion is a non-selective microbial culture medium formulation. Beef Heart Infusion provides nutrients for microbial growth. Beef Heart Infusion can be used for the culture, transplantation and rejuvenation of microorganisms.

HY-B1497

Silver sulfadiazine AgSD	Bacterial DNA/RNA Synthesis Antibiotic	Infection
Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on *bacterial* growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication .

HY-157372

Peptone Bacteriological	Bacterial	Others
Peptone Bacteriological is used as a medium material to provide nitrogen source and amino acid for bacterial growth .

HY-B1781A

Sulfachloropyridazine sodium Sulfachlorpyridazine sodium	Bacterial Antibiotic	Infection
Sulfachloropyridazine (sodium) is a sulfonamide antibiotic that inhibits *bacterial* growth .

HY-149169

Phevamine A	Bacterial	Inflammation/Immunology
Phevamine A is a small molecule bacterial phytotoxin that can be isolated from Pseudomonas syringae. Phevamine promotes bacterial growth by suppressing plant immune responses .

HY-B0343C

Sarafloxacin (hydrochloride) 100 μg/mL in methanol	Bacterial
Sarafloxacin hydrochloride 100 μg/mL in methanol is an antibiotic with activity to inhibit bacterial growth. Sarafloxacin hydrochloride 100 μg/mL in methanol is widely used in veterinary medicine to inhibit bacterial infections. The mechanism of action of Sarafloxacin hydrochloride 100 μg/mL in methanol is mainly achieved by inhibiting the activity of bacterial DNA gyrase. Sarafloxacin hydrochloride 100 μg/mL in methanol is also used in animal feed to improve feed conversion and promote growth.

HY-119606

Bacimethrin NSC 66577	Bacterial Fungal	Infection
Bacimethrin (NSC 66577) is an antibacterial agent and is thiamin biosynthesis antagonist.Bacimethrin inhibits bacterial and yeast growth .

HY-167812

Trimethylsilyl-L-(+)-rhamnose	Bacterial
Trimethylsilyl-L-(+)-rhamnose is a chemically modified version of the natural sugar rhamnose that has activity in studying the role of rhamnose in bacterial cell walls. Trimethylsilyl-L-(+)-rhamnose can be used to explore the composition of bacterial cell walls and their biological functions. Trimethylsilyl-L-(+)-rhamnose can help scientists gain insight into bacterial growth and resistance mechanisms.

HY-111903

Levomecol	Bacterial	Infection
Levomecol (Chloramphenicol), made up of Chloramphenicol, Methyluracil, is a broad-spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae. Levomecol (Chloramphenicol)) stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis .

HY-101479

Iclaprim 3 Publications Verification AR-100	Bacterial Antibiotic	Infection
Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC₉₀ of 0.06 μg/mL.

HY-131045

HADA hydrochloride 4 Publications Verification HCC-Amino-D-alanine hydrochloride	Bacterial	Infection
HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λ_em~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .

HY-126387

Moenomycin complex	Antibiotic Bacterial	Infection
Moenomycin complex is a potent transglycosylase inhibitor. Moenomycin complex inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs) .

HY-W748000

Kocurin PM181104; Baringolin	Antibiotic Bacterial	Infection
Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria .

HY-W039859

2-Chloro-4-nitrophenyl β-D-glucopyranoside, 98%	Biochemical Assay Reagents	Others
2-Chloro-4-nitrophenyl β-D-glucopyranoside, 98% is a substrate for β-glucosidase, used as a bacterial growth medium.

HY-W329071

Rose Bengal	Bacterial Fungal	Infection
Rose Bengal is a photosensitizer that acts on microbial cells. Rose Bengal inhibits yeast cells and other microorganisms growth and even causing death in the presence of light and oxygen. Rose Bengal can be used to inhibit bacterial growth, limit the colony size of filamentous fungi, and suppress the growth of "spreading fungi" like Rhizopus and Trichoderma .

HY-157351

E.Coli Broth	Biochemical Assay Reagents	Others
E.Coli Broth is a selectively concentrated broth that can be used to isolate, detect or culture E. coli.

HY-B1497R

Silver sulfadiazine (Standard) AgSD (Standard)	Reference Standards Bacterial DNA/RNA Synthesis Antibiotic	Infection
Silver sulfadiazine (Standard) is the analytical standard of Silver sulfadiazine. This product is intended for research and analytical applications. Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication .

HY-19487

Ribocil	Bacterial	Infection
Ribocil is a selective inhibitor targeting the bacterial FMN riboswitch, regulating the bacterial riboflavin riboswitch. Ribocil competitively binds to the FMN binding site, mimicking the natural ligand FMN to induce conformational changes in the riboswitch, inhibiting ribB gene expression, reducing riboflavin synthesis, and thus inhibiting bacterial growth. Ribocil strongly inhibits GFP expression (EC₅₀=0.3 μM). Ribocil exhibits in vivo antibacterial activity in a mouse model and can be used to study antibacterial drugs related to drug-resistant bacterial infections and bacterial riboflavin metabolic pathways[1][2].

HY-160679

BaENR-IN-1	Bacterial	Infection
BaENR-IN-1 (Compound 5) is an inhibitor of Enoyl-Acyl Carrier Protein Reductase (ENR) (IC₅₀= 7.7 μM). BaENR-IN-1 blocks the synthesis of fatty acids essential for bacterial growth by inhibiting the bacterial enzyme ENR. BaENR-IN-1 shows activity against *bacteria* .

HY-136638

ML328	Bacterial	Infection
ML328 is a selective inhibitor of bacterial AddAB and RecBCD helicase-nucleases with IC₅₀ values of 26 and 5.1 μM, respectively. ML328 is a gyrase inhibitor. ML328 strongly inhibits the growth of E. coli in the presence of phage. ML328 can be used for the research of bacterial infection .

HY-117963

Lincosamine	Antibiotic	Infection
Lincosamine is a lincosamide antibiotic with activity that inhibits bacterial growth. Lincosamine is primarily produced by Streptomyces lincolnensis. Lincosamine has shown efficacy in combating certain bacterial infections, especially against Klebsiella pneumoniae. Lincosamine ranked among 14 other antimicrobial compounds in its activity against Klebsiella pneumoniae in a test .

HY-143483

NBTIs-IN-5	Bacterial	Infection
NBTIs-IN-5 (Compound 5r) is a NBTI (Novel Bacterial Topoisomerase Inhibitor) DNA gyrase inhibitor with an IC₅₀ of 1.5 μM against Mycobacterium abscessus (Mabs) DNA gyrase. NBTIs-IN-5 inhibits Mabs bamboo bacterial growth with an MIC₉₀ of 0.4 μM .

HY-P3601

Brain Derived Basic Fibroblast Growth Factor (1-24) FGF basic (1-24)	Bacterial HBV	Infection Inflammation/Immunology
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research .

HY-B0200BS

Cephalexin-d5 monohydrate Cefalexin hydrate-d₅; Cephacillin hydrate-d₅	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Cephalexin-d₅ (monohydrate) is the deuterium labeled Cephalexin monohydrate. Cephalexin monohydrate is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin monohydrate kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-150330

DNA ligase-IN-1	Bacterial DNA/RNA Synthesis	Infection
DNA ligase-IN-1 (Compound 1) is an inhibitor of bacterial NAD ⁺-dependent DNA ligase (LigA). DNA ligase-IN-1 effectively inhibits the growth of Staphylococcus aureus in vitro .

HY-B0200S

Cephalexin-d5 Cefalexin-d₅; Cephacillin-d₅	Antibiotic Bacterial	Infection
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-161028

Antibacterial agent 167	Carbonic Anhydrase Bacterial	Infection
Antibacterial agent 167 (compound 13) is an inhibitor of pathogenic bacterial carbonic anhydrases. Antibacterial agent 167 inhibits the growth of N. gonorrhea strains at concentrations ranging from 16 to 64 µg/mL .

HY-B1207

Urethane 3 Publications Verification Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane	Bacterial Parasite	Infection Neurological Disease Cancer
Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress *bacterial, protozoal, sea urchin egg, and plant tissue growth* in vitro .

HY-125650

Pseudouridimycin 1 Publications Verification PUM	Antibiotic DNA/RNA Synthesis Bacterial Nucleoside Antimetabolite/Analog	Infection
Pseudouridimycin (PUM) is an antibiotic that selectively inhibits bacterial RNA polymerase (RNAP), with an IC₅₀ of about 0.1 μM and MICs of 4-6 μg/mL. Pseudouridimycin is a C-nucleoside analogue that's effective against both Gram-negative and Gram-positive bacteria. Pseudouridimycin inhibits bacterial growth in vitro and shows activity in a mouse model of purulent streptococcal peritonitis .

HY-157380

Salmonella-Shigella Agar SS Agar	Biochemical Assay Reagents	Others
Salmonella-Shigella Agar (SS Agar) is a solid medium that can be used for the isolation, detection and culture of Salmonella and Shigella.

HY-W009274

N-Acetylmuramic acid MurNAc; NAMA	p38 MAPK NF-κB Bacterial	Infection Inflammation/Immunology
N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity . N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme . N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape . N-Acetylmuramic acid inhibits the p38 MAPK/NF-κB signaling pathway, and exhibits anti-inflammatory activity. N-Acetylmuramic acid is orally active .

HY-D0024

Sudan I Solvent Yellow 14	Bacterial	Others
Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .

HY-P5723

Api137	Bacterial	Infection
Api137 is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain .

HY-125650A

Pseudouridimycin TFA PUM TFA	Antibiotic DNA/RNA Synthesis Bacterial Nucleoside Antimetabolite/Analog	Infection
Pseudouridimycin (PUM) TFA is an antibiotic that selectively inhibits bacterial RNA polymerase (RNAP), with an IC₅₀ of about 0.1 μM and MICs of 4-6 μg/mL. Pseudouridimycin TFA is a C-nucleoside analogue that's effective against both Gram-negative and Gram-positive bacteria. Pseudouridimycin TFA inhibits bacterial growth in vitro and shows activity in a mouse model of purulent streptococcal peritonitis .

HY-139424

SQ609	Bacterial	Cancer
SQ609 is a lead compound from a library of dipiperidines. SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells. SQ609 displays a potent antitubercular activity .

HY-101479R

Iclaprim (Standard) AR-100 (Standard)	Reference Standards Bacterial Antibiotic	Infection
Iclaprim (Standard) is the analytical standard of Iclaprim. This product is intended for research and analytical applications. Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC₉₀ of 0.06 μg/mL.

HY-W016477

Phenazine	Bacterial	Infection
Phenazine is an electron shuttles, which modulates the redox state of cells and the downstream gene expression related to biofilm formation and bacterial survival. Phenazines is a biocontrol agents, which affects the growth of plants and induces the systemic resistance in plants .

HY-135599

Lysine hydroxamate	Bacterial	Infection
Lysine hydroxamate is an amino acid hydroxamate that inhibits the growth of Escherichia coli K-12. Of the other amino acid hydroxamates tested, only L-lysine hydroxamate reduced the growth rate. The inhibition of growth by L-serine hydroxamate could be rapidly reversed by adding L-serine to the bacterial culture or by removing the analog by filtration. This reversal was specific for L-serine. L-alanine, glycine, or adenine had no effect on the inhibited culture. There was no evidence for active transport of the analog.

HY-149881

Quorum sensing-IN-2	Bacterial	Infection
Quorum sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1 .

HY-Y0444

D-Tyrosine	Tyrosinase	Metabolic Disease
D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .

HY-112176

Kanosamine hydrochloride 2 Publications Verification	Fungal Bacterial Antibiotic	Infection
Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few *bacterial* species. Kanosamine inhibits Phytophthora medicaginis M2913 and Aphanomyces euteiches WI-98 with MICs of 25 and 60 μg/mL, respectively.

HY-P5723A

Api137 TFA	Bacterial	Infection
Api137 TFA is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 TFA inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain .

HY-23848

8-Nonynoic acid non-8-ynoic acid	Bacterial	Infection
8-Nonynoic acid (non-8-ynoic acid) is a fatty acid that belongs to the group of octynoic acids. It exhibits antibacterial activity against gram-positive bacteria by binding to bacterial fatty acids. 8-Nonynoicacid also inhibits growth of gram-negative bacteria by inhibiting the synthesis of fatty acids. It is also capable of inhibiting growth of both aerobic and anaerobic bacteria in biochemical assays.

HY-W019776

Sudan I-d5 Solvent Yellow 14-d₅	Bacterial	Infection
Sudan I-d₅ is a the deuterated Sudan I. Sudan I is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .

HY-107780A

Cyclic-di-GMP sodium c-di-GMP sodium; cyclic diguanylate sodium; 5GP-5GP sodium	STING Endogenous Metabolite	Cancer
Cyclic-di-GMP sodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP sodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP sodium can be used in cancer research .

HY-107780

Cyclic-di-GMP c-di-GMP; cyclic diguanylate; 5GP-5GP	STING Endogenous Metabolite	Cancer
Cyclic-di-GMP is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP can be used in cancer research .

Cat. No.	Product Name

HY-L067

Antibiotics Library

730 compounds

Antibiotics are types of antimicrobial products used for the treatment and prevention of bacterial infections. Antibiotics can kill or inhibit bacterial growth. Although the target of an antibiotic is bacteria, some antibiotics also attack fungi and protozoans. However, antibiotics rarely have an effect on viruses. The major mechanism underlying antibiotics is the inhibition or regulation of enzymes involved in cell wall biosynthesis, nucleic acid metabolism and repair, protein synthesis, or disruption of membrane structure. Many of these cellular functions targeted by antibiotics are most active in multiplying cells. Since there is often overlap in these functions between prokaryotic bacterial cells and eukaryotic mammalian cells, it is not surprising that some antibiotics have also been found to be useful as anticancer agents.

MCE supplies a unique collection of 730 antibiotics, including penicillins, cephalosporins, tetracyclines, macrolides, etc. MCE Antibiotics Library is a useful tool for anti-bacterial or anti-cancer drugs discovery.

Cat. No.	Product Name	Type

HY-D1117

NADA-green NADA hydrochloride	Fluorescent Dyes/Probes
NADA-green is a fluorescent D-amino acid probe. NADA-green is efficiently incorporated into the peptidoglycan of diverse bacterial species peptidoglycan biosynthesis. NADA-green allows probing of bacterial growth with minimal perturbation .

HY-131045

HADA hydrochloride 4 Publications Verification HCC-Amino-D-alanine hydrochloride	Dyes
HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λ_em~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .

HY-D0024

Sudan I Solvent Yellow 14	Dyes
Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .

HY-D0024R

Sudan I (Standard) Solvent Yellow 14 (Standard)	Dyes
Sudan I (Standard) is the analytical standard of Sudan I. This product is intended for research and analytical applications. Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .

Cat. No.	Product Name	Type

HY-W034067

Silver nitrite	Microbial Culture
Silver nitrite is an inorganic compound with the chemical formula AgNO₂. Silver nitrite can inhibit cell division and *bacterial* growth by interfering with protein synthesis .

HY-157374

Beef Heart Infusion	Microbial Culture
Beef Heart Infusion is a non-selective microbial culture medium formulation. Beef Heart Infusion provides nutrients for microbial growth. Beef Heart Infusion can be used for the culture, transplantation and rejuvenation of microorganisms.

HY-W039859

2-Chloro-4-nitrophenyl β-D-glucopyranoside, 98%	Carbohydrates
2-Chloro-4-nitrophenyl β-D-glucopyranoside, 98% is a substrate for β-glucosidase, used as a bacterial growth medium.

HY-W009274

N-Acetylmuramic acid

MurNAc; NAMA

Enzyme Substrates

N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity . N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme . N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape . N-Acetylmuramic acid inhibits the p38 MAPK/NF-κB signaling pathway, and exhibits anti-inflammatory activity. N-Acetylmuramic acid is orally active .

HY-W016477

Phenazine	Biochemical Assay Reagents
Phenazine is an electron shuttles, which modulates the redox state of cells and the downstream gene expression related to biofilm formation and bacterial survival. Phenazines is a biocontrol agents, which affects the growth of plants and induces the systemic resistance in plants .

HY-157372

Peptone Bacteriological	Microbial Culture
Peptone Bacteriological is used as a medium material to provide nitrogen source and amino acid for bacterial growth .

HY-119606

Bacimethrin NSC 66577	Cell Assay Reagents
Bacimethrin (NSC 66577) is an antibacterial agent and is thiamin biosynthesis antagonist.Bacimethrin inhibits bacterial and yeast growth .

HY-167812

Trimethylsilyl-L-(+)-rhamnose

Carbohydrates

Trimethylsilyl-L-(+)-rhamnose is a chemically modified version of the natural sugar rhamnose that has activity in studying the role of rhamnose in bacterial cell walls. Trimethylsilyl-L-(+)-rhamnose can be used to explore the composition of bacterial cell walls and their biological functions. Trimethylsilyl-L-(+)-rhamnose can help scientists gain insight into bacterial growth and resistance mechanisms.

HY-157351

E.Coli Broth	Microbial Culture
E.Coli Broth is a selectively concentrated broth that can be used to isolate, detect or culture E. coli.

HY-157380

Salmonella-Shigella Agar SS Agar	Microbial Culture
Salmonella-Shigella Agar (SS Agar) is a solid medium that can be used for the isolation, detection and culture of Salmonella and Shigella.

HY-139411

White mineral oil Paraffin oil	Co-solvents
White mineral oil is the highly refined mineral oil, and is composed of saturated aliphatic and alicyclic nonpolar hydrocarbons. White mineral oil is biologically and chemically stable, and doesn’t support pathogenic bacterial growth. White mineral oil can resist moisture, extend, soften, smoothen, and lubricate .

HY-W014338

Phenyl(9H-purin-6-yl)amine	Microbial Culture
Phenyl(9H-purin-6-yl)amine is an antibacterial compound with the activity of inhibiting bacterial growth. The application of phenyl(9H-purin-6-yl)amine can be used to develop new antibacterial compounds. Phenyl(9H-purin-6-yl)amine has shown potential inhibitory effects in medical research.

Cat. No.	Product Name	Target	Research Area

HY-P3601

Brain Derived Basic Fibroblast Growth Factor (1-24) FGF basic (1-24)	Bacterial HBV	Infection Inflammation/Immunology
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research .

HY-P5723A

Api137 TFA	Bacterial	Infection
Api137 TFA is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 TFA inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain .

HY-13718

Oglufanide H-Glu-Trp-OH; L-Glutamyl-L-tryptophan	VEGFR HCV Endogenous Metabolite	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits *vascular endothelial growth* factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV)** and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .

HY-W748000

Kocurin PM181104; Baringolin	Antibiotic Bacterial	Infection
Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria .

HY-P5723

Api137	Bacterial	Infection
Api137 is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain .

HY-N11615R

Cyclo(Pro-Val) (Standard)	Peptides Reference Standards	Others
Tylosin (tartrate) (Standard) is the analytical standard of Tylosin (tartrate). This product is intended for research and analytical applications. Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1207

Urethane 3 Publications Verification Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane	Infection Structural Classification Natural Products Microorganisms Neurological Disease Classification of Application Fields Source classification Disease Research Fields	Bacterial Parasite
Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress *bacterial, protozoal, sea urchin egg, and plant tissue growth* in vitro .

HY-125650

Pseudouridimycin 1 Publications Verification PUM	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic DNA/RNA Synthesis Bacterial Nucleoside Antimetabolite/Analog
Pseudouridimycin (PUM) is an antibiotic that selectively inhibits bacterial RNA polymerase (RNAP), with an IC₅₀ of about 0.1 μM and MICs of 4-6 μg/mL. Pseudouridimycin is a C-nucleoside analogue that's effective against both Gram-negative and Gram-positive bacteria. Pseudouridimycin inhibits bacterial growth in vitro and shows activity in a mouse model of purulent streptococcal peritonitis .

HY-W009274

N-Acetylmuramic acid MurNAc; NAMA	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	p38 MAPK NF-κB Bacterial
N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity . N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme . N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape . N-Acetylmuramic acid inhibits the p38 MAPK/NF-κB signaling pathway, and exhibits anti-inflammatory activity. N-Acetylmuramic acid is orally active .

HY-Y0444

D-Tyrosine	Structural Classification Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Tyrosinase
D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .

HY-107780B

Cyclic-di-GMP diammonium Maximum Cited Publications 6 Publications Verification c-di-GMP diammonium; cyclic diguanylate diammonium; 5GP-5GP diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP diammonium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP diammonium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP diammonium can be used in cancer research .

HY-111903

Levomecol	Infection Structural Classification Plant Cell Culture Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial
Levomecol (Chloramphenicol), made up of Chloramphenicol, Methyluracil, is a broad-spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae. Levomecol (Chloramphenicol)) stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis .

HY-W748000

Kocurin PM181104; Baringolin	Microorganisms Source classification	Antibiotic Bacterial
Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria .

HY-107780A

Cyclic-di-GMP sodium c-di-GMP sodium; cyclic diguanylate sodium; 5GP-5GP sodium	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP sodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP sodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP sodium can be used in cancer research .

HY-107780

Cyclic-di-GMP c-di-GMP; cyclic diguanylate; 5GP-5GP	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP can be used in cancer research .

HY-N12108

Forphenicine	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Phenols	Phosphatase
Forphenicine is a bacterial metabolite that is found in S. fulvoviridis and an inhibitor of alkaline phosphatase. Forphenicine inhibits the growth of HL-60 leukemia cells at 10 µM. Forphenicine also increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE) .

HY-110382

Cyclic-di-GMP disodium Maximum Cited Publications 6 Publications Verification c-di-GMP disodium; cyclic diguanylate disodium; 5GP-5GP disodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	STING Endogenous Metabolite
Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research .

HY-N14351

Ferrocin A	Structural Classification Natural Products Microorganisms Source classification	SARS-CoV Bacterial Antibiotic
Ferrocin A is a lipopeptide compound that targets the SARS-CoV-2 RNA-dependent RNA polymerase (nsp12). Ferrocin A can stably bind to nsp12, and as an iron-chelating peptide, it reduces the concentration of free iron in the environment via complexation, thereby inhibiting *bacterial* growth by repressing the acquisition of essential metal cations. As an iron-chelating antiviral molecule, Ferrocin A may be used in studies related to COVID-19 and bacterial infections .

HY-B1828

Spectinomycin	Microorganisms Source classification	Antibiotic Bacterial
Spectinomycin is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin acts by selectively targeting to the *bacterial* ribosome and interrupting protein synthesis. Spectinomycin is also a noncompetitive inhibitor of td intron RNA .

HY-B0438

Spectinomycin dihydrochloride 3 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Resistance Selection Source classification Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the *bacterial* ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an K_i value of 7.2 mM ^- .

HY-107486

Nosiheptide Multhiomycin; RP 9671	Infection Structural Classification Microorganisms Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits *bacterial* protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .

HY-B1207R

Urethane (Standard) Ethyl carbamate (Standard); Carbamic acid ethyl ester (Standard); Ethylurethane (Standard)	Structural Classification Natural Products Microorganisms Source classification	Reference Standards Bacterial Parasite
Urethane (Standard) is the analytical standard of Urethane. This product is intended for research and analytical applications. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .

HY-N12255

COTC	Structural Classification Natural Products Microorganisms Source classification	Glyoxalase (GLO)
COTC is a bacterial metabolite with anticancer activity that is found in S. griseosporeus. COTC inhibits glyoxalase in the presence of glutathione (GSH). COTC also inhibits the proliferation of HeLa cells (IC₅₀ = 18 µg/mL), as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model .

HY-13718

Oglufanide H-Glu-Trp-OH; L-Glutamyl-L-tryptophan	Cardiovascular Disease Structural Classification Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	VEGFR HCV Endogenous Metabolite
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits *vascular endothelial growth* factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV)** and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .

HY-B0519B

Tylosin phosphate 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0519A

Tylosin 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0438R

Spectinomycin dihydrochloride (Standard)	Structural Classification Microorganisms Antibiotics Resistance Selection Source classification Mammalian Cell Culture Antibacterial Disease Research Other Antibiotics	Reference Standards Bacterial Antibiotic
Spectinomycin (dihydrochloride) (Standard) is the analytical standard of Spectinomycin (dihydrochloride). This product is intended for research and analytical applications. Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM[1]-[5].

HY-107486R

Nosiheptide (Standard) Multhiomycin (Standard); RP 9671 (Standard)	Structural Classification Microorganisms Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Other Antibiotics	Reference Standards Bacterial Antibiotic
Nosiheptide (Standard) is the analytical standard of Nosiheptide. This product is intended for research and analytical applications. Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .

HY-B0519

Tylosin tartrate 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-N14139

Dioxamycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Dioxamycin has anti-Gram-positive bacterial activity. Dioxamycin can inhibit Staphylococcus aureus 209P with a MIC of 3.12 μg/mL. Dioxamycin inhibits the growth of L1210, P388, IMC, LX-1 and SC-6 cells with IC₅₀s (μg/mL) of 2.7, 1.4, 6.0, 2.0 and 2.5, respectively .

HY-B0519AR

Tylosin (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research	Reference Standards Bacterial Antibiotic
Tylosin (Standard) is the analytical standard of Tylosin. This product is intended for research and analytical applications. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0519BR

Tylosin phosphate (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Animal Husbandry Antibacterial Disease Research	Reference Standards Bacterial Antibiotic
Tylosin (phosphate) (Standard) is the analytical standard of Tylosin (phosphate). This product is intended for research and analytical applications. Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-W012530

Phenylpyruvic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite PDI
Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity .

HY-122485

α-Copaene	Structural Classification Natural Products Classification of Application Fields Leguminosae Source classification Other Diseases Sindora Plants Disease Research Fields	Bacterial
α-Copaene is a potent attractant for male Mediterranean fruit flies Ceratitis capitata.α-Copaene can be found as a minor component in the essential oils of various plant species. α-Copaene can inhibit *bacterial* growth with a minimum inhibitory concentration of 0.5-1 μL/mL. α-Copaene suppresses biofilm formation by decreasing the hydrophobicity of the cell surface. α-Copaene can be used as an oviposition promoter of Bactrocera oleae .

HY-B0519R

Tylosin tartrate (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research	Reference Standards Bacterial Antibiotic
Tylosin (tartrate) (Standard) is the analytical standard of Tylosin (tartrate). This product is intended for research and analytical applications. Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-N11615R

Cyclo(Pro-Val) (Standard)	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Others Reference Standards
Tylosin (tartrate) (Standard) is the analytical standard of Tylosin (tartrate). This product is intended for research and analytical applications. Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B1350A

Fusidic acid sodium salt 2 Publications Verification Sodium fusidate; SQ-16360	Infection Triterpenes Structural Classification Microorganisms Classification of Application Fields Terpenoids Source classification Disease Research Fields Cancer	Bacterial Antibiotic Interleukin Related
Fusidic acid sodium salt is an orally available antibacterial agent that inhibits *bacterial* protein synthesis by preventing the release of translation elongation factor G (EF-G) from ribosomes. Fusidic acid sodium salt inhibits the inhibitory and activating effects of interleukins IL-1 and IL-6 on glucose-induced insulin production and exhibits antidiabetic effects in a rat model. Fusidic acid sodium salt improves the symptoms of colitis in rats and inhibits the growth of Toxoplasma gondii and Listeria monocytogenes EGD in vitro, but not in mice .

HY-W012530R

Phenylpyruvic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite	Reference Standards Endogenous Metabolite PDI
Phenylpyruvic acid (Standard) is the analytical standard of Phenylpyruvic acid. This product is intended for research and analytical applications. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity .

HY-W015954

(2R,3R)-Butane-2,3-diol	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Calcium Channel Bacterial
(2R,3R)-Butane-2,3-diol is a non-covalent, reversible agonist targeting lanthanum (La ³⁺)-sensitive calcium channels in bacteria (e.g., Escherichia coli) with an EC₅₀ of approximately 25 mM. (2R,3R)-Butane-2,3-diol binds to calcium channel proteins or related complexes, induces channel opening, promotes extracellular calcium influx, and triggers intracellular calcium transients, which may regulate bacterial physiological activities such as growth, metabolism, and signal transduction. (2R,3R)-Butane-2,3-diol mediates bacterial-host cell signaling interactions and affects the metabolic balance of intestinal microorganisms, and can be used to study lactose intolerance and other related diseases .

HY-12326A

c-di-AMP disodium 4 Publications Verification Cyclic diadenylate disodium; Cyclic-di-AMP disodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	STING Bacterial Endogenous Metabolite
c-di-AMP (Cyclic diadenylate) sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-12326B

c-di-AMP diammonium 4 Publications Verification Cyclic diadenylate diammonium; Cyclic-di-AMP diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	STING Bacterial Endogenous Metabolite
c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-12326

c-di-AMP Cyclic diadenylate; Cyclic-di-AMP	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	STING Bacterial Endogenous Metabolite
c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP (Cyclic diadenylate) acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-N6712

Thiolutin 3 Publications Verification Acetopyrrothin	Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Metabolic Disease Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial Deubiquitinase NOD-like Receptor (NLR) DNA/RNA Synthesis Pyroptosis HMG-CoA Reductase (HMGCR)
Thiolutin (Acetopyrrothin) is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. Thiolutin can be produced by Streptomyces. Thiolutin inhibits AMSH (IC₅₀ = 4 μM) and Rpn11 (IC₅₀ = 0.53 μM). Thiolutin is a dual inhibitor of BRCC36 and the NLRP3 inflammasome, exhibiting anti-inflammatory effects. Thiolutin effectively suppresses the interaction between BRCC36 and HMGCR, leading to the inhibition of HCC growth. Thiolutin attenuates pyroptosis and NLRP3 inflammasome activation. Thiolutin markedly alleviates renal injury and inflammatory process in IgAN. Thiolutin is an anti-angiogenic compound which can ease Doxorubicin-induced cardiotoxicity (DOXIC) ^{[1][2][3][4][5]}.

HY-N4314

Scutellarein tetramethyl ether 2 Publications Verification 4',5,6,7-Tetramethoxyflavone	Infection Structural Classification Flavonoids Classification of Application Fields Flavones Plants Compositae Genista maderensis (Webb & Berthel.) Lowe Inflammation/Immunology Disease Research Fields	Bacterial COX NO Synthase NF-κB
Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC₅₀= 20.08 μg/mL) .

HY-121120

Isosulfazecin	Structural Classification Microorganisms Antibiotics Source classification Beta-lactam Antibiotics	Antibiotic
Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .

HY-N4314R

Scutellarein tetramethyl ether (Standard) 4',5,6,7-Tetramethoxyflavone (Standard)	Structural Classification Flavonoids Flavones Plants Compositae Genista maderensis (Webb & Berthel.) Lowe	Reference Standards Bacterial COX NO Synthase NF-κB
Scutellarein tetramethyl ether (Standard) is the analytical standard of Scutellarein tetramethyl ether. This product is intended for research and analytical applications. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC₅₀= 20.08 μg/mL) .

HY-N6712R

Thiolutin (Standard) Acetopyrrothin (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Reference Standards Antibiotic Bacterial Deubiquitinase NOD-like Receptor (NLR) DNA/RNA Synthesis Pyroptosis HMG-CoA Reductase (HMGCR)
Thromycin (Standard) is the analytical standard of thromycin (HY-N6712). Thiolutin (Acetopyrrothin) is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. Thiolutin can be produced by Streptomyces. Thiolutin inhibits AMSH (IC₅₀ = 4 μM) and Rpn11 (IC₅₀ = 0.53 μM). Thiolutin is a dual inhibitor of BRCC36 and the NLRP3 inflammasome, exhibiting anti-inflammatory effects. Thiolutin effectively suppresses the interaction between BRCC36 and HMGCR, leading to the inhibition of HCC growth. Thiolutin attenuates pyroptosis and NLRP3 inflammasome activation. Thiolutin markedly alleviates renal injury and inflammatory process in IgAN. Thiolutin is an anti-angiogenic compound which can ease Doxorubicin-induced cardiotoxicity (DOXIC) ^{[1][2][3][4][5]}.

HY-W015954R

(2R,3R)-Butane-2,3-diol (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Calcium Channel Bacterial
(2R,3R)-Butane-2,3-diol (Standard) is the analytical standard of (2R,3R)-Butane-2,3-diol (HY-W015954). This product is intended for research and analytical applications. (2R,3R)-Butane-2,3-diol is a non-covalent, reversible agonist targeting lanthanum (La ³⁺)-sensitive calcium channels in bacteria (e.g., Escherichia coli) with an EC₅₀ of approximately 25 mM. (2R,3R)-Butane-2,3-diol binds to calcium channel proteins or related complexes, induces channel opening, promotes extracellular calcium influx, and triggers intracellular calcium transients, which may regulate bacterial physiological activities such as growth, metabolism, and signal transduction. (2R,3R)-Butane-2,3-diol mediates bacterial-host cell signaling interactions and affects the metabolic balance of intestinal microorganisms, and can be used to study lactose intolerance and other related diseases .

Cat. No.	Product Name	Chemical Structure

HY-B0200S

Cephalexin-d5
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-W019776

Sudan I-d5
Sudan I-d₅ is a the deuterated Sudan I. Sudan I is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .

HY-B1207S

Urethane-d5
Urethane-d₅ is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .

HY-Y0444S1

D-Tyrosine-d4
D-Tyrosine-d₄ is the deuterium labeled D-Tyrosine (HY-Y0444) . D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .

HY-Y0444S2

D-Tyrosine-d7
D-Tyrosine-d₇ is the deuterium labeled D-Tyrosine (HY-Y0444) . D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .

HY-B0200BS

Cephalexin-d5 monohydrate

Cephalexin-d₅ (monohydrate) is the deuterium labeled Cephalexin monohydrate. Cephalexin monohydrate is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin monohydrate kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-101479S

Iclaprim-d6
Iclaprim-d₆ (AR-100-d6) is the deuterium labeled Iclaprim. Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.

HY-Y0444S

D-Tyrosine-d2
D-Tyrosine-d₂ is the deuterium labeled D-Tyrosine (HY-Y0444) . D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .

HY-W751750

Urethane-13C,15N
Urethane- ¹³C, ¹⁵N (Ethyl carbamate- ¹³C, ¹⁵N) is the ¹³C- and ¹⁵N-labeled Urethane (HY-B1207). Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .

HY-B0519AS

Tylosin-d3

Tylosin-d₃ is the deuterium labeled Tylosin. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-110382S

13C20,15N10-Cyclic di-GMP sodium

¹³C20, ¹⁵N10-Cyclic di-GMP ( ¹³C20, ¹⁵N10-c-di-GMP) is ¹³C and ¹⁵N labeled Cyclic-di-GMP (disodium). Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research .

HY-B0268S2

Enoxacin-d8 hydrate

Enoxacin-d₈ (hydrate) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 μg/ml) and topoisomerase IV (IC₅₀=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

HY-B0268S1

Enoxacin-d8 hydrochloride

Enoxacin-d₈ (hydrochloride) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 μg/ml) and topoisomerase IV (IC₅₀=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

HY-W015490S

1,4-Naphthoquinone-d6

1,4-Naphthoquinone-d₆ is the deuterium labeled 1,4-Naphthoquinone. 1,4-Naphthoquinone is an inhibitor with broad-spectrum inhibitory activity targeting DNA polymerase, NF-κB and monoamine oxidase (MAO-A/B), with antibacterial and anti-biofilm efficacy. 1,4-Naphthoquinone is a competitive inhibitor of MAO-B (Ki=1.4 μM) and a non-competitive inhibitor of MAO-A (Ki=7.7 μM). 1,4-Naphthoquinone inhibits DNA polymerase pol α, β, γ, δ, ε, λ with IC₅₀ ranging from 5.57-128 μM. 1,4-Naphthoquinone inhibits tumor cell proliferation, induces apoptosis and necrosis, and has anti-angiogenic and anti-inflammatory activities by inducing oxidative stress, depleting glutathione (GSH), inhibiting DNA polymerase-mediated DNA synthesis and blocking NF-κB nuclear translocation. 1,4-Naphthoquinone can be used in anti-bacterial , anti-tumor and anti-inflammatory studies, including inhibition of melanoma and colon cancer cell growth and endothelial cell function, as well as LPS-induced inflammation models .

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