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Results for "

active intermediate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Intermediate (25) 5 alpha Reductase (1) Amylases (2) Amyloid-β (2) Antibiotic (4) Apoptosis (9) Bacterial (7) Bcr-Abl (1) Biochemical Assay Reagents (10) Calcium Channel (1) Cytochrome P450 (3) Dengue Virus (1) Drug Derivative (1) Drug Metabolite (3) Endogenous Metabolite (19) Flavivirus (1) Fungal (4) FXR (1) GABA Receptor (1) Glucosylceramide Synthase (GCS) (1) Glutathione S-transferase (1) Glycosidase (2) Histamine Receptor (1) Histone Methyltransferase (1) Isotope-Labeled Compounds (5) Keap1-Nrf2 (1) Ligands for E3 Ligase (1) Liposome (1) Mitosis (1) NO Synthase (2) Proteasome (1) RAR/RXR (2) Reactive Oxygen Species (2) Trk Receptor (2) α-synuclein (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (6) Infection (10) Inflammation/Immunology (16) Metabolic Disease (3) Neurological Disease (12)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Cationic Lipids (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Targets Recommended: Drug Intermediate

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010076

Methyl 2,4-dihydroxybenzoate	Drug Intermediate	Others
Methyl 2,4-dihydroxybenzoate is a key intermediate and can be used for the formation of other active compounds .

HY-Y1230

4-Pentynoic acid Propargylacetic acid	Biochemical Assay Reagents	Others
4-Pentynoic acid (Propargylacetic acid) is an *intermediate* to produce biologically active compounds. 4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers . 4-Pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-Y0038

2-Bromo-6-methoxynaphthalene	Trk Receptor	Cancer
2-Bromo-6-methoxynaphthalene is an active intermediate in the production of anti-inflammatory agents like Naproxen and Nabumetone by Heck reaction. 2-Bromo-6-methoxynaphthalene has potential anti-inflammatory properties and Tyrosine-protein inhibitor properties. 2-Bromo-6-methoxynaphthalene can be used for the research of cancer .

HY-Y0038R

2-Bromo-6-methoxynaphthalene (Standard)	Trk Receptor	Cancer
2-Bromo-6-methoxynaphthalene (Standard) is the analytical standard of 2-Bromo-6-methoxynaphthalene. This product is intended for research and analytical applications. 2-Bromo-6-methoxynaphthalene is an active intermediate in the production of anti-inflammatory agents like Naproxen and Nabumetone by Heck reaction. 2-Bromo-6-methoxynaphthalene has potential anti-inflammatory properties and Tyrosine-protein inhibitor properties. 2-Bromo-6-methoxynaphthalene can be used for the research of cancer .

HY-41940

Dasatinib intermediate-1	Bcr-Abl	Cancer
Dasatinib intermediate-1 is an intermediate in the synthesis of Dasatinib (HY-10181). Dasatinib Is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity .

HY-B0989

Carzenide 4-Sulfamoylbenzoic acid	Drug Intermediate	Others
Carzenide is an organic synthesis intermediate used for the synthesis of active molecules.

HY-W012860

p-Tolualdehyde 2 Publications Verification	Drug Intermediate	Others
p-Tolualdehyde is the active small molecule, that could used as drug intermediate .

HY-W016779

Cyclopentyl phenyl ketone	Endogenous Metabolite	Others
Cyclopentyl phenyl ketone is an organic synthesis intermediate used for the synthesis of active molecules .

HY-113864

Diisobutyl carbinol	Drug Metabolite	Metabolic Disease
Diisobutyl carbinol (DIBC) is an orally active organic solvent widely used as industrial intermediates and fragrance ingredient. Diisobutyl carbinol and Diisobutyl ketone are well interconverted metabolically in rats .

HY-W708309

2-Methoxy ketamine hydrochloride	Drug Derivative	Others
2-Methoxy ketamine hydrochloride is an organic synthesis intermediate used for the synthesis of active molecules.

HY-W041194

Tropic acid DL-Tropic acid	Drug Intermediate	Others
Tropic acid (DL-Tropic acid) is an active small molecule that can be used as the pharmaceutical intermediate .

HY-W156596

3-Methoxybenzothioamide	Drug Intermediate	Others
3-Methoxybenzothioamide is an active small molecule, that can be ussed as drug intermediate .

HY-W041194R

Tropic acid (Standard) DL-Tropic acid (Standard)	Drug Intermediate	Others
Tropic acid (DL-Tropic acid) is an active small molecule that can be used as the pharmaceutical intermediate .

HY-W010611

3,3-Dimethylacrylic acid 3-Methylcrotonic acid; 3-Methylbut-2-enoic acid	Bacterial	Infection
3,3-Dimethylacrylic acid is an active small molecule, that can be used as drug intermediate .

HY-W877989

BWA-522 intermediate-1	Ligands for E3 Ligase	Cancer
BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7 .

HY-W000949

4-(Hydroxymethyl)benzeneboronic acid	Biochemical Assay Reagents Drug Intermediate	Others
4-(Hydroxymethyl)benzeneboronic acid is an important intermediate. 4-(Hydroxymethyl)benzeneboronic acid can be used for the synthesis of other active compounds .

HY-W078632

2-Mercapto-4,6-dimethylnicotinonitrile	Drug Intermediate	Others
2-Mercapto-4,6-dimethylnicotinonitrile can be used as an intermediate to synthesize biologically active compounds, such as aminomethyl derivatives .

HY-126181

5-Formylcytosine	Endogenous Metabolite	Others
5-Formylcytosine is a modified base, which is oxidized from 5-methylcytosine. 5-Formylcytosine is a intermediate of in the active DNA demethylation .

HY-115243

2-Chloro-1,4-naphthoquinone	Drug Intermediate	Others
2-Chloro-1,4-naphthoquinone is an reactive intermediate. 2-Chloro-1,4-naphthoquinone can be used for the research of various biochemical studies .

HY-W012860R

p-Tolualdehyde (Standard)	Drug Intermediate	Others
p-Tolualdehyde (Standard) is the analytical standard of p-Tolualdehyde. This product is intended for research and analytical applications. p-Tolualdehyde is the active small molecule, that could used as drug intermediate .

HY-133952

7-Oxotridecanedioic acid	Liposome	Cancer
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .

HY-40351

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine	Biochemical Assay Reagents	Others
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a key intermediate when preparing active pharmaceutical ingredient .

HY-W002011

Quinoline-2-carboxylic acid 1 Publications Verification	Glycosidase Amylases	Metabolic Disease
Quinoline-2-carboxylic acid exhibits antidiabetic activity. Quinoline-2-carboxylic acid can be used as drug intermediate for synthesis of various active compounds .

HY-135380

Atorvastatin acetonide tert-butyl ester	Drug Intermediate	Cardiovascular Disease
Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .

HY-76082

L-Pyroglutamic acid 2 Publications Verification	Endogenous Metabolite	Inflammation/Immunology
L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-41000

2-Amino-4-bromopyridine 4-Bromopyridine-2-amine	Biochemical Assay Reagents Drug Intermediate	Others
2-Amino-4-bromopyridine (4-Bromopyridine-2-amine) is an important intermediate, which can be used for the synthesis of other active compounds .

HY-I0308

1-Methyl-1H-pyrazole-4-boronic acid pinacol ester	Biochemical Assay Reagents Drug Intermediate	Others
1-Methyl-1H-pyrazole-4-boronic acid pinacol ester is an organic synthetic intermediate, which can be used to synthesize other active compounds .

HY-76082A

L-Pyroglutamic acid sodium	Endogenous Metabolite	Inflammation/Immunology
L-Pyroglutamic acid sodium is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid sodium is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid sodium can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-108932

Gemcitabine monophosphate Gemcitabine 5′-phosphate	Apoptosis	Cancer
Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles .

HY-108932A

Gemcitabine monophosphate disodium Gemcitabine 5′-phosphate disodium	Apoptosis	Cancer
Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles .

HY-14843

Imagabalin PD-0332334(free base)	GABA Receptor	Neurological Disease
Imagabalin (PD-0332334 free base) is an active compound with activity for studying neurological diseases. The synthesis of imagabalin involves the reaction of 3-methylvaleric acid and Meldrum acid. During the synthesis of imagabalin, an acyl chloride intermediate species, 3-methylvaleryl chloride, was revealed for the first time. The synthesis of imagabalin also provided new information about the reaction mechanism, indicating that 3-methylvaleric anhydride is an important intermediate .

HY-B2124

10,11-Dihydrocarbamazepine	Drug Metabolite	Neurological Disease
10,11-Dihydrocarbamazepine is the active metabolite of Oxcarbazepine. 10,11-Dihydrocarbamazepine also is an intermediate. Oxcarbazepine is rapidly and almost completely converted to 10,11-Dihydrocarbamazepine with probable Anticonvulsant efficacy .

HY-Y0185

4'-Nitroacetophenone	Biochemical Assay Reagents Drug Intermediate	Others
4'-Nitroacetophenone is a nitroaromatic compound. 4'-Nitroacetophenone is an important organic synthetic intermediate, which can be used for the synthesis of other active compounds such as Chloramphenicol (HY-B0239) .

HY-B0242

Sulfanilamide 2 Publications Verification Sulphanilamide	Bacterial Antibiotic	Infection
ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum .

HY-76082S

L-Pyroglutamic acid-d5 1 Publications Verification	Isotope-Labeled Compounds Endogenous Metabolite	Inflammation/Immunology
L-Pyroglutamic acid-d₅ is the deuterium labeled L-Pyroglutamic acid (HY-76082). L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-20128

Piperazin-2-one	Drug Intermediate	Others
Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds .

HY-N0420A

Succinic acid tromethamine Wormwood acid tromethamine	Endogenous Metabolite	Neurological Disease
Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries .

HY-30236

5-Bromoindole	Drug Intermediate	Cancer
5-Bromoindole is a chemical intermediate. 5-Bromoindole derivatives have anticancer activity against breast cancer. 5-Bromoindole can be used to synthesize GSK-3 inhibitors and anticancer active molecules .

HY-125598

Secologanin	Cytochrome P450	Others
Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin .

HY-N0420S2

Succinic acid-13C4	Endogenous Metabolite	Neurological Disease
Succinic acid- ¹³C₄ is the ¹³C labeled Succinic acid . Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries .

HY-W012997

Tetrahydro-2H-pyran-2-one δ-valerolactone	Endogenous Metabolite	Others
Tetrahydro-2H-pyran-2-one (δ-valerolactone) is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-W010611R

3,3-Dimethylacrylic acid (Standard) 3-Methylcrotonic acid (Standard); 3-Methylbut-2-enoic acid (Standard)	Bacterial	Infection
3,3-Dimethylacrylic acid (Standard) (3-Methylcrotonic acid (Standard)) is the analytical standard of 3,3-Dimethylacrylic acid (HY-W010611). This product is intended for research and analytical applications.3,3-Dimethylacrylic acid is an active small molecule, that can be used as drug intermediate.

HY-N4283

Coniferyl alcohol	Drug Intermediate Fungal	Infection Cardiovascular Disease Inflammation/Immunology
Coniferyl alcohol is an orally active lignin biosynthesis intermediate and antifungal agent. Coniferyl alcohol specifically inhibits the growth of fungi (Verticillium longisporum). Coniferyl alcohol inhibits the growth of Nicotiana benthamiana seedlings. Coniferyl alcohol improves cardiac dysfunction in renovascular hypertension and cardiac inflammation .

HY-N0420S4

Succinic acid-13C2	Endogenous Metabolite	Neurological Disease
Succinic acid- ¹³C₂ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

HY-N0420S3

Butanedioic acid-13C2	Endogenous Metabolite	Neurological Disease
Butanedioic acid- ¹³C₂ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

HY-B0242R

Sulfanilamide (Standard)	Bacterial Antibiotic	Infection
Sulfanilamide (Standard) is the analytical standard of Sulfanilamide. This product is intended for research and analytical applications. ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum .

HY-N3007

Naringenin chalcone 2 Publications Verification	Drug Intermediate Apoptosis NO Synthase	Inflammation/Immunology Cancer
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties .

HY-N14756

6"'-Deamino-6"'-hydroxyneomycin B	Antibiotic Bacterial	Infection
6"'-Deamino-6"'-hydroxyneomycin B is an aminoglycosyl antibiotic that can be produced by Streptomyces fradiae UC 75 and is active against both Gram-positive and Gram-negative bacteria. 6"'-Deamino-6"'-hydroxyneomycin B can be used as an intermediate in the biosynthesis of neomycin .

HY-W007509

1H-Indol-5-amine 5-Aminoindole	Biochemical Assay Reagents Drug Intermediate	Others
1H-Indol-5-amine (5-Aminoindole) is an organic compound containing an indole ring structure and belongs to the class of indole derivatives. 1H-Indol-5-amine can serve as a key intermediate for the synthesis of other active compounds .

HY-135380R

Atorvastatin acetonide tert-butyl ester (Standard)	Drug Intermediate	Cardiovascular Disease
Atorvastatin acetonide tert-butyl ester (Standard) is the analytical standard of Atorvastatin acetonide tert-butyl ester. This product is intended for research and analytical applications. Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .

Cat. No.	Product Name	Type

HY-W000949

4-(Hydroxymethyl)benzeneboronic acid	Biochemical Assay Reagents
4-(Hydroxymethyl)benzeneboronic acid is an important intermediate. 4-(Hydroxymethyl)benzeneboronic acid can be used for the synthesis of other active compounds .

HY-40351

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine	Biochemical Assay Reagents
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a key intermediate when preparing active pharmaceutical ingredient .

HY-41000

2-Amino-4-bromopyridine 4-Bromopyridine-2-amine	Biochemical Assay Reagents
2-Amino-4-bromopyridine (4-Bromopyridine-2-amine) is an important intermediate, which can be used for the synthesis of other active compounds .

HY-I0308

1-Methyl-1H-pyrazole-4-boronic acid pinacol ester	Biochemical Assay Reagents
1-Methyl-1H-pyrazole-4-boronic acid pinacol ester is an organic synthetic intermediate, which can be used to synthesize other active compounds .

HY-Y0185

4'-Nitroacetophenone	Biochemical Assay Reagents
4'-Nitroacetophenone is a nitroaromatic compound. 4'-Nitroacetophenone is an important organic synthetic intermediate, which can be used for the synthesis of other active compounds such as Chloramphenicol (HY-B0239) .

HY-20128

Piperazin-2-one	Biochemical Assay Reagents
Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds .

HY-W007509

1H-Indol-5-amine 5-Aminoindole	Biochemical Assay Reagents
1H-Indol-5-amine (5-Aminoindole) is an organic compound containing an indole ring structure and belongs to the class of indole derivatives. 1H-Indol-5-amine can serve as a key intermediate for the synthesis of other active compounds .

HY-133952

7-Oxotridecanedioic acid	Drug Delivery
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .

HY-76082A

L-Pyroglutamic acid sodium	Biochemical Assay Reagents
L-Pyroglutamic acid sodium is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid sodium is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid sodium can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-W127651

Dimethyldioctylammonium bromide

Dioctyldimethylammonium bromide

Cell Assay Reagents

Dimethyldioctylammonium bromide is an organic compound containing ammonium and bromide ions. It is commonly used in the production of detergents, emulsifiers and surfactants for various industrial applications. Dimethyldioctylammonium bromide is highly surface active and reduces the surface tension of aqueous solutions, so it can be used to clean and wet surfaces. In addition, it can also be used as an intermediate in the synthesis of other quaternary ammonium compounds.

HY-Y0141

3-Amino-6-chloropyridazine	Biochemical Assay Reagents
3-Amino-6-chloropyridazine is a nitrogen-containing heterocyclic organic compound belonging to the pyridazine derivatives. 3-Amino-6-chloropyridazine has the basicity of amino groups and the nucleophilic substitution activity of chlorine atoms. 3-Amino-6-chloropyridazine can serve as an important intermediate for synthesizing some active compounds .

Cat. No.	Product Name	Target	Research Area

HY-P5422

Caloxin 3A1	Calcium Channel	Others
Caloxin 3A1 is a biological active peptide. (This peptide belongs to caloxins, the extracellular plasma membrane (PM) Ca2+ pump inhibitors. Caloxin 3A1 inhibits plasma membrane calcium pumps (PMCAs) but not the sarcoplasmic reticulum Ca2+-pump. This peptide does not inhibit formation of the acylphosphate intermediate from ATP.)

HY-P5510

Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 HCV NS3 protease substrate	Peptides	Others
Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. (This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W012860

p-Tolualdehyde 2 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Drug Intermediate
p-Tolualdehyde is the active small molecule, that could used as drug intermediate .

HY-W041194

Tropic acid DL-Tropic acid	Microorganisms other families Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Drug Intermediate
Tropic acid (DL-Tropic acid) is an active small molecule that can be used as the pharmaceutical intermediate .

HY-W010611

3,3-Dimethylacrylic acid 3-Methylcrotonic acid; 3-Methylbut-2-enoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Bacterial
3,3-Dimethylacrylic acid is an active small molecule, that can be used as drug intermediate .

HY-W002011

Quinoline-2-carboxylic acid 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Glycosidase Amylases
Quinoline-2-carboxylic acid exhibits antidiabetic activity. Quinoline-2-carboxylic acid can be used as drug intermediate for synthesis of various active compounds .

HY-76082

L-Pyroglutamic acid 2 Publications Verification	Structural Classification Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-125598

Secologanin	Structural Classification Caprifoliaceae Iridoids Classification of Application Fields Lonicera japonica Thunb. Terpenoids Source classification Other Diseases Plants Disease Research Fields	Cytochrome P450
Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin .

HY-W041194R

Tropic acid (Standard) DL-Tropic acid (Standard)	Microorganisms other families Ketones, Aldehydes, Acids Source classification Plants	Drug Intermediate
Tropic acid (DL-Tropic acid) is an active small molecule that can be used as the pharmaceutical intermediate .

HY-W012860R

p-Tolualdehyde (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Drug Intermediate
p-Tolualdehyde (Standard) is the analytical standard of p-Tolualdehyde. This product is intended for research and analytical applications. p-Tolualdehyde is the active small molecule, that could used as drug intermediate .

HY-76082A

L-Pyroglutamic acid sodium	Structural Classification Alkaloids Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Pyroglutamic acid sodium is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid sodium is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid sodium can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-N0420A

Succinic acid tromethamine Wormwood acid tromethamine	Structural Classification Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries .

HY-W012997

Tetrahydro-2H-pyran-2-one δ-valerolactone	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Tetrahydro-2H-pyran-2-one (δ-valerolactone) is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-W010611R

3,3-Dimethylacrylic acid (Standard) 3-Methylcrotonic acid (Standard); 3-Methylbut-2-enoic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Bacterial
3,3-Dimethylacrylic acid (Standard) (3-Methylcrotonic acid (Standard)) is the analytical standard of 3,3-Dimethylacrylic acid (HY-W010611). This product is intended for research and analytical applications.3,3-Dimethylacrylic acid is an active small molecule, that can be used as drug intermediate.

HY-N4283

Coniferyl alcohol	Infection Structural Classification Monophenols Classification of Application Fields Simple Phenylpropanols Source classification Phenols Phenylpropanoids Endogenous metabolite Disease Research Fields	Drug Intermediate Fungal
Coniferyl alcohol is an orally active lignin biosynthesis intermediate and antifungal agent. Coniferyl alcohol specifically inhibits the growth of fungi (Verticillium longisporum). Coniferyl alcohol inhibits the growth of Nicotiana benthamiana seedlings. Coniferyl alcohol improves cardiac dysfunction in renovascular hypertension and cardiac inflammation .

HY-N3007

Naringenin chalcone 2 Publications Verification	Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Human Gut Microbiota Metabolites Chalcones Flavonoids other families Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Drug Intermediate Apoptosis NO Synthase
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties .

HY-N14756

6"'-Deamino-6"'-hydroxyneomycin B	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
6"'-Deamino-6"'-hydroxyneomycin B is an aminoglycosyl antibiotic that can be produced by Streptomyces fradiae UC 75 and is active against both Gram-positive and Gram-negative bacteria. 6"'-Deamino-6"'-hydroxyneomycin B can be used as an intermediate in the biosynthesis of neomycin .

HY-N1282

Seneciphylline	Alkaloids Structural Classification other families Pyrrole Alkaloids Classification of Application Fields Source classification Plants Compositae Sophora yunnanensis C. Y. Ma Disease Research Fields Cancer	Glutathione S-transferase Cytochrome P450
Seneciphylline is an orally effective hepatotoxic inducer. Seneciphylline is metabolized by CYP450 enzymes into active intermediates, which covalently bind to intracellular biomacromolecules such as proteins and DNA to form adducts, which in turn trigger a series of toxic reactions, such as inducing cell apoptosis and damaging mitochondrial function. Seneciphylline can be used in hepatotoxicity research[1][2].

HY-76082R

L-Pyroglutamic acid (Standard)	Structural Classification Immune System Disorder Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite Cardiovascular System Disorder	Endogenous Metabolite
L-Pyroglutamic acid (Standard) is the analytical standard of L-Pyroglutamic acid (HY-76082). This product is intended for research and analytical applications. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid standard can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-N2292

Kinsenoside 3 Publications Verification	Structural Classification Natural Products Classification of Application Fields Orchidaceae Plants Anoectochilus Inflammation/Immunology Disease Research Fields	Keap1-Nrf2 Apoptosis
Kinsenoside is the main active ingredient of the genus plant, and has various biological activities. Kinsenoside and Nrf2 depend on the protection of nuclear cells (NPCs), which significantly reduces their ability to survive. Kinsenoside Active NPC Medium AKT-ERK1/2-Nrf2 Signal passage, Prevent physical decline, aging, harmonious physical function impairment. Kinsenoside can improve the puncture guide model for intermediate vertebral wall discharge (IDD).

HY-N14758

6"'-Deamino-6"'-hydroxyparomomycin I	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
6"'-Deamino-6"'-hydroxyparomomycin I is an amino glycosyl antibiotic that can be produced by Streptomyces rimosus forma paromomycinus A67 15. It is active against both Gram-positive and Gram-negative bacteria. 6"'-Deamino-6"'-hydroxyparomomycin I can be used as an intermediate in the biosynthesis of paromomycin .

HY-113335

Trihydroxycholestanoic acid Coprocholic acid	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease .

HY-N3007R

Naringenin chalcone (Standard)	Structural Classification Human Gut Microbiota Metabolites Chalcones Flavonoids other families Source classification Phenols Polyphenols Plants Endogenous metabolite	Drug Intermediate Apoptosis NO Synthase
Naringenin chalcone (Standard) is an analytical standard of Naringenin chalcone. This product is intended for research and analytical applications. Naringenin chalcone is an orally active intermediate in the biosynthesis of flavonols. Naringenin chalcone induces apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties.

HY-N3187

Nimbin	Other Terpenoids Infection Structural Classification other families Neurological Disease Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	Flavivirus Dengue Virus Fungal Bacterial Histamine Receptor
Nimbin is an orally active intermediate limonoid found in Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier. Nimbin is promising for research of neurodegenerative diseases and viral infections .

HY-W012814

4-Methylcatechol	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite Apoptosis Reactive Oxygen Species
4-Methylcatechol is an intermediate in the degradation of some alkylbenzenes and an orally active suicide inhibitor of catechol 2,3-dioxygenase (C23O). 4-Methylcatechol induces apoptosis in melanoma cells through oxidative stress, but some studies have also shown that 4-Methylcatechol is carcinogenic. In addition, 4-Methylcatechol has antiplatelet and blood pressure-lowering activities. 4-Methylcatechol can also inhibit protein oxidation in beef but does not disulfide formation .

HY-W012814R

4-Methylcatechol (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Phenols Polyphenols Endogenous metabolite	Endogenous Metabolite Apoptosis Reactive Oxygen Species
4-Methylcatechol (Standard) is the analytical standard of 4-Methylcatechol. This product is intended for research and analytical applications. 4-Methylcatechol is an intermediate in the degradation of some alkylbenzenes and an orally active suicide inhibitor of catechol 2,3-dioxygenase (C23O). 4-Methylcatechol induces apoptosis in melanoma cells through oxidative stress, but some studies have also shown that 4-Methylcatechol is carcinogenic. In addition, 4-Methylcatechol has antiplatelet and blood pressure-lowering activities. 4-Methylcatechol can also inhibit protein oxidation in beef but does not disulfide formation[1][2][3][4][5][6].

HY-W014589

2,4-Di-tert-butylphenol 1 Publications Verification 2,4-DTBP	Structural Classification Monophenols Microorganisms Classification of Application Fields Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Fungal Apoptosis RAR/RXR Amyloid-β
2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances .

HY-W014589R

2,4-Di-tert-butylphenol (Standard) 2,4-DTBP (Standard)	Structural Classification Monophenols Microorganisms Source classification Phenols Endogenous metabolite	Endogenous Metabolite Fungal Apoptosis RAR/RXR Amyloid-β
2,4-Di-tert-butylphenol (Standard) is the analytical standard of 2,4-Di-tert-butylphenol (HY-W014589). This product is intended for research and analytical applications. 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities, and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of pharmaceuticals and fragrances .

Cat. No.	Product Name	Chemical Structure

HY-76082S

L-Pyroglutamic acid-d5 1 Publications Verification
L-Pyroglutamic acid-d₅ is the deuterium labeled L-Pyroglutamic acid (HY-76082). L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-N0420S2

Succinic acid-13C4
Succinic acid- ¹³C₄ is the ¹³C labeled Succinic acid . Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries .

HY-N0420S3

Butanedioic acid-13C2
Butanedioic acid- ¹³C₂ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

HY-N0420S4

Succinic acid-13C2
Succinic acid- ¹³C₂ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

HY-76082S1

L-Pyroglutamic acid-13C5

L-Pyroglutamic acid- ¹³C₅ is the ¹³C labeled L-Pyroglutamic acid (HY-76082) . L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-W002011S

Quinoline-2-carboxylic acid-d6
Quinoline-2-carboxylic acid-d₆ is the deuterium labeled Quinoline-2-carboxylic acid (HY-W002011). Quinoline-2-carboxylic acid exhibits antidiabetic activity. Quinoline-2-carboxylic acid can be used as drug intermediate for synthesis of various active compounds .

HY-20128S

Piperazin-2-one-d6
Piperazin-2-one-d₆ is the deuterium labeled Piperazin-2-one (HY-20128). Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds .

HY-W012997S

Tetrahydro-2H-pyran-2-one-d4
Tetrahydro-2H-pyran-2-one-d₄ is the deuterium labeled Tetrahydro-2H-pyran-2-one. Tetrahydro-2H-pyran-2-one is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

Cat. No.	Product Name		Classification

HY-Y1230

4-Pentynoic acid Propargylacetic acid		Alkynes
4-Pentynoic acid (Propargylacetic acid) is an *intermediate* to produce biologically active compounds. 4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers . 4-Pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-133952

7-Oxotridecanedioic acid		Cationic Lipids
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .

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