TIM-1

By Targets:	Small Interfering RNA (siRNA) (4) Transmembrane Glycoprotein (2)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Inflammation/Immunology (2)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (3) siRNAs (4)

Targets Recommended: Tim3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990154

*Anti-Mouse TIM-1/CD365 Antibody (3B3)*	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Anti-Mouse TIM-1/CD365 Antibody (3B3) is a rat-derived IgG2a κ type agonistic antibody, targeting to mouse *TIM-1/CD365. Anti-Mouse TIM-1/CD365 Antibody (3B3) enhances T-cell proliferation and responses by forming a stable TIM-1* complex and bringing TIM-1 into the T-cell receptor (TCR)-CD3 complex. Anti-Mouse TIM-1/CD365 Antibody (3B3) can be used for the researches of cancer, inflammation and immunology, such as experimental autoimmune encephalomyelitis, B16 F10 tumor and transplant ^[1] .

HY-P990822

*Anti-Mouse TIM-1/CD365 Antibody (3D10)*	Transmembrane Glycoprotein	Cardiovascular Disease Inflammation/Immunology
Anti-Mouse TIM-1/CD365 Antibody (3D10) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse *TIM-1/CD365. Anti-Mouse TIM-1/CD365 Antibody (3D10) can block mouse T cell immunoglobulin and mucin domain 1 (TIM-1) also known as CD365. Anti-Mouse TIM-1*/CD365 Antibody (3D10) can be used for the researches of inflammation, immunology and cardiovascular disease, such as graft-versus-host disease (GVHD), airway inflammation and atherosclerosis ^[1] .

HY-RS19510

Havcr1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Havcr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Havcr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Havcr1 Mouse Pre-designed siRNA Set A Havcr1 Mouse Pre-designed siRNA Set A

HY-RS00962

ARHGEF5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ARHGEF5 Human Pre-designed siRNA Set A contains three designed siRNAs for ARHGEF5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ARHGEF5 Human Pre-designed siRNA Set A ARHGEF5 Human Pre-designed siRNA Set A

HY-RS14526

TIMELESS Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TIMELESS Human Pre-designed siRNA Set A contains three designed siRNAs for TIMELESS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TIMELESS Human Pre-designed siRNA Set A TIMELESS Human Pre-designed siRNA Set A

HY-RS06021

HAVCR1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
HAVCR1 Human Pre-designed siRNA Set A contains three designed siRNAs for HAVCR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HAVCR1 Human Pre-designed siRNA Set A HAVCR1 Human Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area

HY-P990154

*Anti-Mouse TIM-1/CD365 Antibody (3B3)*	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Anti-Mouse TIM-1/CD365 Antibody (3B3) is a rat-derived IgG2a κ type agonistic antibody, targeting to mouse *TIM-1/CD365. Anti-Mouse TIM-1/CD365 Antibody (3B3) enhances T-cell proliferation and responses by forming a stable TIM-1* complex and bringing TIM-1 into the T-cell receptor (TCR)-CD3 complex. Anti-Mouse TIM-1/CD365 Antibody (3B3) can be used for the researches of cancer, inflammation and immunology, such as experimental autoimmune encephalomyelitis, B16 F10 tumor and transplant ^[1] .

HY-P990822

*Anti-Mouse TIM-1/CD365 Antibody (3D10)*	Transmembrane Glycoprotein	Cardiovascular Disease Inflammation/Immunology
Anti-Mouse TIM-1/CD365 Antibody (3D10) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse *TIM-1/CD365. Anti-Mouse TIM-1/CD365 Antibody (3D10) can block mouse T cell immunoglobulin and mucin domain 1 (TIM-1) also known as CD365. Anti-Mouse TIM-1*/CD365 Antibody (3D10) can be used for the researches of inflammation, immunology and cardiovascular disease, such as graft-versus-host disease (GVHD), airway inflammation and atherosclerosis ^[1] .

HY-P990875

*Anti-TIM-1/KIM-1/CD365 Antibody (2.70.2)* CR014; CDX-014 antibody	Inhibitory Antibodies	Others
Anti-TIM-1/KIM-1/CD365 Antibody (2.70.2) is antiTIM/KIM-1/CD365of antibodies.

Species:	Human (4) Rhesus Macaque (2) Rat (2) Mouse (1) Cynomolgus (1) Canine (2)
Tag:	His (9) Tag Free (2) Fc (3)
Source:	HEK293 (12)

Cat. No.	Compare	Product Name	Species	Source

HY-P73605

	TIM-1/KIM-1/HAVCR Protein, Human (HEK293) Hepatitis A virus cellular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1	Human	HEK293
	TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His) belongs to a family of immunoglobulin-like domain-containing transmembrane proteins is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. TIM1 (HAVCR1) facilitates attachment of a variety of enveloped viruses, including filoviruses, alphaviruses, and flaviviruses, that display highly conserved phosphatidylserine (PtdSer) on their surface. TIM1 undergoes tyrosine phosphorylation of its C-terminal cytoplasmic tail. TIM-1 can function as a co-stimulatory molecule for T cell activation. TIM-1/KIM-1/HAVCR Protein, Human (HEK293) is the recombinant human-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with tag free.

HY-P73602

	TIM-1/KIM-1/HAVCR Protein, Rat (HEK293, His) Hepatitis A virus cellular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1	Rat	HEK293
	TIM-1/KIM-1/HAVCR protein is a phosphatidylserine receptor that plays a crucial regulatory role in regulatory B cells, affecting their generation, expansion and inhibitory functions. It acts as a ligand for P-selectin/SELPLG and controls activated T cell trafficking during inflammatory responses. TIM-1/KIM-1/HAVCR Protein, Rat (HEK293, His) is the recombinant rat-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with N-His labeled tag.

HY-P73608

	TIM-1/KIM-1/HAVCR Protein, Canine (HEK293, His) Hepatitis A virus cellular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1	Canine	HEK293
	TIM-1/KIM-1/HAVCR Protein, Canine (HEK293, His) is the recombinant canine-derived TIM-1/KIM-1/HAVCR, expressed by HEK293 , with N-His labeled tag. ,

HY-P74510

	TIM-1/KIM-1/HAVCR Protein, Rhesus Macaque (HEK293) Hepatitis A virus cellular receptor 1 homolog; HAVcr-1; KIM-1; TIM-1	Rhesus Macaque	HEK293
	TIM-1/KIM-1/HAVCR Protein, a key member and costimulatory molecule in the T cell immunoglobulin mucin (TIM) family, is expressed on the surface of T cells. It not only directly enhances the antitumor effect of CD8+ T cells and NK cells but also changes the tumor microenvironment to induce more effective antitumor immune response. In addition, agonistic anti-TIM-1 monoclonal antibody or other ligands can enhance the function of T cells, increase CD8+ T cells and NK cells, reduce MDSC in tumor tissues, and inhibit tumor growth. TIM-1/KIM-1/HAVCR Protein, Rhesus Macaque (HEK293) is the recombinant Rhesus Macaque-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with tag free.

HY-P73609

	TIM-1/KIM-1/HAVCR Protein, Canine (HEK293, Fc) Hepatitis A virus cellular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1	Canine	HEK293
	TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His) belongs to a family of immunoglobulin-like domain-containing transmembrane proteins is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. TIM1 (HAVCR1) facilitates attachment of a variety of enveloped viruses, including filoviruses, alphaviruses, and flaviviruses, that display highly conserved phosphatidylserine (PtdSer) on their surface. TIM1 undergoes tyrosine phosphorylation of its C-terminal cytoplasmic tail. TIM-1 can function as a co-stimulatory molecule for T cell activation. TIM-1/KIM-1/HAVCR Protein, Canine (HEK293, Fc) is the recombinant canine-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with N-mFc labeled tag.

HY-P701042

	TIM-1/KIM-1/HAVCR Protein, Cynomolgus (HEK293, His) HAVcr-1; KIM-1; KIM1; TIMD-1; TIMD1; TIM; TIM-1; TIM1; CD365; HAVCR1; HAVCR; HAVCR-1	Cynomolgus	HEK293
	HAVCR1 is a co-stimulatory molecule expressed on the surface of immune cells, which promotes the activation and proliferation of immune cells, promotes the secretion of cytokines, and regulates immune response. HAVCR1 affects tumor progression and patient prognosis by inhibiting the MEK/ERK pathway. TIM-1/KIM-1/HAVCR Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with C-His labeled tag.

HY-P73601

	TIM-1/KIM-1/HAVCR Protein, Rat (HEK293, His-Fc) Hepatitis A virus cellular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1	Rat	HEK293
	TIM-1/KIM-1/HAVCR protein is a phosphatidylserine receptor that plays a crucial regulatory role in regulatory B cells, affecting their generation, expansion and inhibitory functions. It acts as a ligand for P-selectin/SELPLG and controls activated T cell trafficking during inflammatory responses. TIM-1/KIM-1/HAVCR Protein, Rat (HEK293, His-Fc) is the recombinant rat-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with N-hFc, C-His labeled tag.

HY-P73604

	TIM-1/KIM-1/HAVCR Protein, Human (HEK293, His-Fc) Hepatitis A virus cellular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1	Human	HEK293
	TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His) belongs to a family of immunoglobulin-like domain-containing transmembrane proteins is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. TIM1 (HAVCR1) facilitates attachment of a variety of enveloped viruses, including filoviruses, alphaviruses, and flaviviruses, that display highly conserved phosphatidylserine (PtdSer) on their surface. TIM1 undergoes tyrosine phosphorylation of its C-terminal cytoplasmic tail. TIM-1 can function as a co-stimulatory molecule for T cell activation. TIM-1/KIM-1/HAVCR Protein, Human (HEK293, His-Fc) is the recombinant human-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with N-hFc, C-His labeled tag.

HY-P74512

	TIM-1/KIM-1/HAVCR Protein, Rhesus Macaque (116a.a, HEK293, His) Hepatitis A virus cellular receptor 1 homolog; HAVcr-1; KIM-1; TIM-1	Rhesus Macaque	HEK293
	TIM-1/KIM-1/HAVCR Protein, a key member and costimulatory molecule in the T cell immunoglobulin mucin (TIM) family, is expressed on the surface of T cells. It not only directly enhances the antitumor effect of CD8+ T cells and NK cells but also changes the tumor microenvironment to induce more effective antitumor immune response. In addition, agonistic anti-TIM-1 monoclonal antibody or other ligands can enhance the function of T cells, increase CD8+ T cells and NK cells, reduce MDSC in tumor tissues, and inhibit tumor growth. TIM-1/KIM-1/HAVCR Protein, Rhesus Macaque (116a.a, HEK293, His) is the recombinant Rhesus Macaque-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with N-His labeled tag.

HY-P73606

	TIM-1/KIM-1/HAVCR Protein, Human (270a.a, HEK293, His) Hepatitis A virus cellular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1	Human	HEK293
	TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His) belongs to a family of immunoglobulin-like domain-containing transmembrane proteins is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. TIM1 (HAVCR1) facilitates attachment of a variety of enveloped viruses, including filoviruses, alphaviruses, and flaviviruses, that display highly conserved phosphatidylserine (PtdSer) on their surface. TIM1 undergoes tyrosine phosphorylation of its C-terminal cytoplasmic tail. TIM-1 can function as a co-stimulatory molecule for T cell activation. TIM-1/KIM-1/HAVCR Protein, Human (270a.a, HEK293, His) is the recombinant human-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with N-His labeled tag.

HY-P73607

	TIM-1/KIM-1/HAVCR Protein, Human (135a.a, HEK293, His) Hepatitis A virus cellular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1	Human	HEK293
	TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His) belongs to a family of immunoglobulin-like domain-containing transmembrane proteins is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. TIM1 (HAVCR1) facilitates attachment of a variety of enveloped viruses, including filoviruses, alphaviruses, and flaviviruses, that display highly conserved phosphatidylserine (PtdSer) on their surface. TIM1 undergoes tyrosine phosphorylation of its C-terminal cytoplasmic tail. TIM-1 can function as a co-stimulatory molecule for T cell activation. TIM-1/KIM-1/HAVCR Protein, Human (135a.a, HEK293, His) is the recombinant human-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with C-His labeled tag.

HY-P71365

	TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, C-His) Hepatitis A virus cellular receptor 1 homolog; HAVcr-1; Kidney injury molecule 1; KIM-1; T cell membrane protein 1; TIM-1	Mouse	HEK293
	The TIM-1/KIM-1/HAVCR protein is a phosphatidylserine receptor that is critical for B cell homeostasis, affecting generation, expansion, and inhibitory functions. As a P-selectin/SELPLG ligand, it facilitates trafficking of activated T cells during inflammation and controls T cell accumulation in the inflamed central nervous system. TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with C-6*His labeled tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81186

	TIM 1 Antibody (YA3545) HAVCR; HAVCR 1; HA; Vcr-1; hepatitis A virus cellular receptor 1; HKIM-1; Kidney Injury Molecule1; KIM1; KIM 1; KIM-1; TIM-1; TIMD 1; TIMD1; KM-1; TIMD1_HUMAN; T cell immunoglobin domain and mucin domain protein 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell membrane protein 1. 肾脏损伤分子1	WB	Human, Mouse, Rat
	TIM 1 Antibody (YA3545) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TIM 1.

HY-P84722

	TIM 1 Antibody (YA4419) TIM; KIM1; TIM1; CD365; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1	WB, ELISA	Human, Mouse
	TIM 1 Antibody (YA4419) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TIM 1.

HY-P82459

	TIMELESS Antibody (YA2204) hTIM; TIM; TIM1; TIMeless; TIMeless circadian clock 1; TIMELESS1	WB, IHC-F, IHC-P, ICC/IF	Human
	TIMELESS Antibody (YA2204) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TIMELESS.

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Cat. No.	Product Name		Classification

HY-RS19510

Havcr1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Havcr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Havcr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS00962

ARHGEF5 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ARHGEF5 Human Pre-designed siRNA Set A contains three designed siRNAs for ARHGEF5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14526

TIMELESS Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TIMELESS Human Pre-designed siRNA Set A contains three designed siRNAs for TIMELESS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS06021

HAVCR1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
HAVCR1 Human Pre-designed siRNA Set A contains three designed siRNAs for HAVCR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides