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Results for "

Pim

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Pim (82) Akt (1) Anaplastic lymphoma kinase (ALK) (1) Apoptosis (24) Autophagy (5) Bacterial (1) c-Kit (1) Casein Kinase (6) Caspase (1) CDK (10) Checkpoint Kinase (Chk) (1) DAPK (2) DYRK (3) EGFR (1) ERK (1) FLT3 (1) Fluorescent Dye (1) GSK-3 (4) HDAC (2) Interleukin Related (1) IRAK (1) Isotope-Labeled Compounds (1) MELK (2) mTOR (6) NF-κB (2) PARP (1) PI3K (2) PKC (1) PKD (3) Reference Standards (2) Ribosomal S6 Kinase (RSK) (2) RIP kinase (2) Small Interfering RNA (siRNA) (9) Src (2) Trk Receptor (2)
By Research Areas:	Cancer (84) Cardiovascular Disease (2) Infection (3) Inflammation/Immunology (10) Metabolic Disease (1) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (3) Mouse Pre-designed siRNA Sets (3) Human Pre-designed siRNA Sets (3) siRNAs (9)

103

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: Pim

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-111552

PIM1-IN-1	Pim	Cancer
PIM1-IN-1 is a potent and highly selective *PIM1/3* inhibitor, with IC₅₀s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC₅₀ of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity .

HY-108605

PIM1-IN-2	Pim	Cancer
PIM1-IN-2 is a potent and ATP competitive *Pim-1* inhibitor with a K_i of 91 nM. PIM1-IN-2 targets the ATP-binding kinase hinge region not by forming classical hydrogen bonds .

HY-19322B

PIM-447 dihydrochloride 5+ Cited Publications LGH447 dihydrochloride	Pim Apoptosis	Cancer
PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor, with K_i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis .

HY-19322

PIM447 5+ Cited Publications LGH447	Pim Apoptosis	Cancer
PIM447 (LGH447) is a potent, orally available, and selective pan-PIM kinase inhibitor, with K_i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis .

HY-160006

PIM-IN-2	Pim	Cancer
PIM-IN-2 (Pim-2) is a *Pim* kinases inhibitor (IC₅₀ = 25 nM). PIM-IN-2 promotes cell survival, is antiapoptotic, and has exhibited an elevated level of expression in a variety of human tumors .

HY-RS10547

PIM1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PIM1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIM1 Human Pre-designed siRNA Set A PIM1 Human Pre-designed siRNA Set A

HY-143897

PIM1-IN-3	Pim Apoptosis	Cancer
PIM1-IN-3 (Compound HL8) is a potent inhibitor of *PIM1. PIM1-IN-3 shows selective inhibition for the PIM-1 enzyme. PIM1-IN-3 induces apoptosis efficiently in Colo320 cells. PIM*1-IN-3 has the potential for the research of cancer diseases .

HY-163442A

PIM3-IN-1 hydrochloride	Pim	Cancer
PIM3-IN-1 hydrochloride (Compound 19a) is an inhibitor of (PIM2/3), with the highest inhibition level being against *PIM3, having an IC₅₀* value in the nanomolar range. PIM3-IN-1 hydrochloride can be used in cancer research .

HY-175277

PIM1-IN-8	Pim NF-κB Interleukin Related	Inflammation/Immunology
PIM1-IN-8 is a *PIM1/p65* pathway inhibitor. PIM1-IN-8 suppresses the expression of α-SMA and collagen I in activated fibroblasts and blocks TGF-β induced migration. PIM1-IN-8 alleviates pulmonary fibrosis in a Bleomycin (BLM) (HY-17565A)-induced pulmonary fibrosis mice model. PIM1-IN-8 can be used for the study of idiopathic pulmonary fibrosis (IPF) .

HY-143898

PIM1-IN-4	Pim	Cancer
PIM1-IN-4 (Compound 8) is a potent inhibitor of *PIM1. PIM1-IN-4 reveals strong inhibition of five other enzymes, i.e., SGK-1, PKA, CaMK-1, GSK3β, and MSK1. PIM*1-IN-4 has the potential for the research of cancer diseases .

HY-147921

PIM1-IN-7	Pim	Cancer
PIM1-IN-7 (compound 6c) is a potent *PIM-1* inhibitor, with an IC₅₀ of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC₅₀ values of 42.9 and 7.68 μM, respectively .

HY-147920

PIM1-IN-6	Pim	Cancer
PIM1-IN-6 (compound 5h) is a potent *PIM-1* inhibitor, with an IC₅₀ of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC₅₀ values of 1.51 and 15.2 μM, respectively .

HY-147785

Pim-1 kinase inhibitor 2	Pim Apoptosis	Cancer
Pim-1 kinase inhibitor 2 (Compound 13) is a potent inhibitor of Pim-1 kinase. Pim-1 kinase inhibitor 2 induces apoptosis. Pim-1 kinase inhibitor 2 has the potential for the research of cancer diseases .

HY-143295

Pim-1 kinase inhibitor 1	Pim Apoptosis	Cancer
Pim-1 kinase inhibitor 1 is a *Pim-1* kinase inhibitor with an IC₅₀ of 0.11 μM for Pim-1 kinase. Pim-1 kinase inhibitor 1 shows anticancer activity to several cancer cell lines by promotes cell apoptosis. Pim-1 kinase inhibitor 1 can be used for the research of cancer .

HY-143233

PIM-1/HDAC-IN-1	Pim HDAC Apoptosis	Cancer
PIM-1/HDAC-IN-1 (compound 4d) is a *PIM-1* inhibitor, with an IC₅₀ of 343.87 nM. PIM-1/HDAC-IN-1 has strong inhibitory activity and selectivity against HDAC 1 and HDAC 6, with IC₅₀ values of 63.65 and 62.39 nM, respectively. PIM-1/HDAC-IN-1 exhibits apoptosis inducing potential in MCF-7 cell lines. PIM-1/HDAC-IN-1 shows pre-G1 apoptosis and cell cycle arrest at G2/M phase .

HY-168517

PIM-1/CK2-IN-2	Pim Casein Kinase Apoptosis	Cancer
PIM-1/CK2-IN-2 (compound 3aA) is a *PIM-1/CK2* inhibitor. PIM-1/CK2-IN-2 can induce the mitochondrial apoptotic pathway in CCRF-CEM cells. PIM-1/CK2-IN-2 can be used in cancer research .

HY-142656

PIM-IN-1	Pim	Cancer
PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC₅₀ = 61 nM; pS6, EC₅₀ = 71 nM).

HY-174302

PIM-1/HDAC-IN-2	Pim HDAC PARP Apoptosis	Cancer
PIM-1/HDAC-IN-2 is a robust *PIM/HDAC* inhibitor (IC₅₀ = 0.11 μM in MV4-11cells), which exerts a synergistic antiproliferative effect through a dual mechanism of inhibiting *PIM1* kinase and selectively inhibiting HDAC6. PIM-1/HDAC-IN-2 induces cell apoptosis. PIM-1/HDAC-IN-2 remarkably induces the cleavage of PARP, thereby initiating the arrest of the cell cycle in G1 phase and a reduction in S phase. PIM-1/HDAC-IN-2 demonstrates significant anticancer efficacyin the MV4-11 xenograft model without notable toxicity^[1]_.

HY-168071

Pim-1 kinase inhibitor 11	Pim	Cancer
Pim-1 kinase inhibitor 11 (10f) is a *PIM-1* inhibitor, with an IC₅₀ of 0.18 μM. Pim-1 kinase inhibitor 11 (10f) exhibits anticancer activity. Pim-1 kinase inhibitor 11 (10f) induces apoptosis and arrests cell cycle progression .

HY-156915

Pim-1 kinase inhibitor 13	Pim	Inflammation/Immunology Cancer
Pim-1 Kinase Inhibitor 13 (compound 10) is a Pim-1 kinase inhibitor with an IC₅₀ of 4.41 μM. Pim-1 Kinase Inhibitor 13 can be utilized in immunology or cancer research .

HY-162059

Pim-1 kinase inhibitor 10	Pim Apoptosis Caspase	Cancer
Pim-1 kinase inhibitor 10 (compound 13a) is a both competitive and non-competitive inhibitor of PIM-1/2 kinase. Pim-1 kinase inhibitor 10 can induce cell apoptosis and exhibits anticancer activity. Pim-1 kinase inhibitor 10 also induces caspase 3/7 activation .

HY-163119

Pim-1 kinase inhibitor 9	Pim	Cancer
Pim-1 kinase inhibitor 9 (compound 8b) is a selective inhibitor against Pim-1 kinase with IC₅₀ value of 0.24 µM. Pim-1 kinase inhibitor 9 inhibits cell cycle of T47D at S phase. Pim-1 kinase inhibitor 9 reveals antitumor activity .

HY-149976

Pim-1 kinase inhibitor 4	Pim	Cancer
Pim-1 kinase inhibitor 4 (Compound 10f) is a Pim-1 kinase inhibitor (IC₅₀: 17.01 nM). Pim-1 kinase inhibitor 4 also has antioxidant activity and inhibits DPPH. Pim-1 kinase inhibitor 4 induces apoptosis in PC-3 cell, and inhibits PC-3 cell growth with an IC₅₀ of 16 nM. Pim-1 kinase inhibitor 4 can be used for research of prostate cancer .

HY-150731

Pim-1 kinase inhibitor 3	Pim	Cancer
Pim-1 kinase inhibitor 3 (Compound H5) is a potent *Pim-1* kinase inhibitor with an IC₅₀ of 35.13 nM .

HY-W412264

Pim-1/2 kinase inhibitor 1	Pim	Cancer
Pim-1/2 kinase inhibitor 1 is an orally active pim-1/2 kinase inhibitor. Pim-1/2 kinase inhibitor 1 blocks the ability of Pim kinases to phosphorylate peptides, and inhibits the pim protein kinase directed phosphorylation of 4E-BP1 and p27 ^Kip1. Pim-1/2 kinase inhibitor 1 can be used in study of cancer, especially prostate cancer .

HY-162006

Pim-1 kinase inhibitor 8	PKC Pim	Cancer
Pim-1 kinase inhibitor 8 (compound 12) is a potent inhibitor of Pim-1 kinase with an IC₅₀ of 14.3 nM. Pim-1 kinase inhibitor 8 has potent cytotoxicity against MCF-7 and HepG2 cells with IC₅₀s of 0.5 and 5.27 μM, respectively. Pim-1 kinase inhibitor 8 can used in study breast cancer .

HY-149996

Pim-1 kinase inhibitor 6	Pim	Cancer
Pim-1 kinase inhibitor 6 (Compound 4d) is a potent Pim-1 kinase inhibitor with IC₅₀ value of 0.46 μM, and has significant cytotoxic effect on cancer cells .

HY-149995

Pim-1 kinase inhibitor 5	Pim	Cancer
Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC₅₀: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC₅₀s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells .

HY-157404

Pim-1/2 kinase inhibitor 2	Pim	Cancer
Pim-1/2 kinase inhibitor 2 (compound 5b) is a competitive *PIM-1* and PIM-2 kinase inhibitor with IC₅₀s of 1.31 μM and 0.67 μM, respectively. Pim-1/2 kinase inhibitor 2 shows in-vitro low cytotoxicity against normal human lung fibroblast Wi-38 cell line and potent in-vitro anticancer activity against myeloid leukaemia (NFS-60), liver (HepG-2), prostate (PC-3), and colon (Caco-2) cancer cell lines .

HY-101947

SMI-16a 5 Publications Verification Pim1/2 Kinase Inhibitor VI	Pim	Cancer
SMI-16a is a selective *Pim* kinase inhibitor with IC₅₀ values of 0.15, 0.02 and 48 μM for Pim1, Pim2 and PC3 cells, respectively.

HY-RS10548

Pim1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pim1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pim1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pim1 Mouse Pre-designed siRNA Set A Pim1 Mouse Pre-designed siRNA Set A

HY-RS10551

Pim2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pim2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pim2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pim2 Mouse Pre-designed siRNA Set A Pim2 Mouse Pre-designed siRNA Set A

HY-RS10550

PIM2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PIM2 Human Pre-designed siRNA Set A contains three designed siRNAs for PIM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIM2 Human Pre-designed siRNA Set A PIM2 Human Pre-designed siRNA Set A

HY-RS10552

Pim2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pim2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pim2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pim2 Rat Pre-designed siRNA Set A Pim2 Rat Pre-designed siRNA Set A

HY-RS10555

Pim3 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA) Pim	Others
Pim3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pim3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pim3 Rat Pre-designed siRNA Set A Pim3 Rat Pre-designed siRNA Set A

HY-RS10554

Pim3 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA) Pim	Others
Pim3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pim3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pim3 Mouse Pre-designed siRNA Set A Pim3 Mouse Pre-designed siRNA Set A

HY-RS10549

Pim1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pim1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pim1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pim1 Rat Pre-designed siRNA Set A Pim1 Rat Pre-designed siRNA Set A

HY-RS10553

PIM3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) Pim	Others
PIM3 Human Pre-designed siRNA Set A contains three designed siRNAs for PIM3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIM3 Human Pre-designed siRNA Set A PIM3 Human Pre-designed siRNA Set A

HY-10371

Pim1/AKK1-IN-1 5+ Cited Publications LKB1/AAK1 dual inhibitor	Pim	Cancer
Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with K_d values of 35 nM/53 nM/75 nM/380 nM for *Pim1/AKK1/MST2/LKB1* respectively, and also inhibits MPSK1 and TNIK.

HY-135816

*CK2/PIM1-IN-1*	Casein Kinase Pim	Inflammation/Immunology Cancer
CK2/PIM1-IN-1 is an inhibitor of CK2 and *PIM1, with IC₅₀s of 3.787 μM and 4.327 μM for CK2 and PIM1, respectively. CK2/PIM*1-IN-1 is developed for the research of proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation, pain, vascular disorders, pathogenic infections and certain immunological disorders .

HY-18095A

CX-6258 hydrochloride hydrate 2 Publications Verification	Pim	Cancer
CX-6258 hydrochloride hydrate is a potent and kinase selective *pan-Pim* kinases inhibitor, with IC₅₀*s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim*-3, respectively .

HY-18095

CX-6258 2 Publications Verification	Pim	Cancer
CX-6258 is a potent and kinase selective *pan-Pim* kinases inhibitor, with IC₅₀*s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim*-3, respectively .

HY-18095B

CX-6258 hydrochloride 2 Publications Verification	Pim	Cancer
CX-6258 hydrochloride is a potent and kinase selective *pan-Pim* kinases inhibitor, with IC₅₀*s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim*-3, respectively .

HY-18086

*TCS PIM-1 1* 4 Publications Verification SC 204330	Pim	Cancer
TCS PIM-1 1 (SC 204330) is a potent, selective and ATP-competitive *Pim-1* kianse inhibitor with an IC₅₀ of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2 (IC₅₀s >20000 nM) .

HY-13287A

SGI-1776	Pim Apoptosis Autophagy	Inflammation/Immunology Cancer
SGI-1776 is an inhibitor of Pim kinases, with IC₅₀s of 7 nM, 363 nM, and 69 nM for Pim-1, Pim-2 and Pim-3, respectively .

HY-132867

*MNK/PIM-IN-1*	Pim	Cancer
MNK/PIM-IN-1 represents an innovative dual *MNK/PIM* inhibitor with a good pharmacokinetic profile.

HY-142696

*CDK6/PIM1-IN-1*	CDK Pim Apoptosis	Cancer
CDK6/PIM1-IN-1 is a potent and balanced dual *CDK6/PIM1* inhibitor with IC₅₀ values of 39 and 88 nM, respectively. CDK6/PIM1-IN-1 inhibits CDK4 (IC₅₀=3.6 nM). CDK6/PIM1-IN-1 significantly inhibits acute myeloid leukemia (AML) cell proliferation, arrest cell cycle at the G1 phase, and promote cell apoptosis. CDK6/PIM1-IN-1 exhibits potent anti-AML activity .

HY-173224

*CDK2/PIM1-IN-1*	CDK Pim	Cancer
CDK2/PIM1-IN-1 is an inhibitor of CDK2 (IC₅₀: 0.27 μM) and *PIM1* (IC₅₀: 0.67 μM) kinases. CDK2/PIM1-IN-1 induces apoptosis and reduces tumor-promoting TNF-α expression. CDK2/PIM1-IN-1 has antitumor activity .

HY-142696A

*CDK6/PIM1-IN-1 hydrochloride*	CDK Pim Apoptosis	Cancer
CDK6/PIM1-IN-1 (Compound 51) hydrochloride is an orally active and potent dual *CDK6/PIM1* inhibitor with IC₅₀ values of 39 and 88 nM, respectively. CDK6/PIM1-IN-1 hydrochloride inhibits CDK4 (IC₅₀=3.6 nM). CDK6/PIM1-IN-1 hydrochloride significantly inhibits acute myeloid leukemia (AML) cell proliferation, arrest cell cycle at the G1 phase, and promote cell apoptosis. CDK6/PIM1-IN-1 exhibits potent anti-AML activity .

HY-16576A

SMI-4a 1 Publications Verification TCS-Pim-1-4a	Pim	Cancer
SMI-4a (TCS-PIM-1-4a) is a poten, selective, cell-permeable and ATP-competitive *Pim-1* inhibitor with an IC₅₀ of 24 μM and a K_i of 0.6 μM. SMI-4a also inhibits *Pim-2* (IC₅₀ of 100 μM), and does not significantly inhibit the other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity .

Cat. No.	Product Name

HY-L008

JAK/STAT Compound Library

599 compounds

The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is central to signaling by cytokine receptors, a superfamily of more than 30 transmembrane proteins that recognize specific cytokines, and is critical in blood formation and immune response. Canonical JAK/STAT signaling begins with the association of cytokines and their corresponding transmembrane receptors. Activated JAKs then phosphorylate latent STAT monomers, leading to dimerization, nuclear translocation, and DNA binding. In mammals, there are four JAKs (JAK1, JAK2, JAK3, TYK2) and seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6). Since the JAK/STAT pathway plays a major role in many fundamental processes, such as apoptosis and inflammation, dysfunctional proteins in the pathway may lead to a number of diseases. For example, alterations in JAK/STAT signalling can result in cancer and diseases affecting the immune system, such as severe combined immunodeficiency disorder (SCID).

MCE provides 599 compounds that can be used in the study of the JAK/STAT signaling pathway and related diseases.

Cat. No.	Product Name	Type

HY-D2415

BODIPY-FL staurosporine

Fluorescent Dyes/Probes

BODIPY-FL staurosporine (Compound 8a) is a fluorescence probe based on staurosporine, exhibiting high specificity towards tyrosine kinases (TK) and tyrosine kinase-like (TKL) family kinases. BODIPY-FL staurosporine has the potential to develop binding assays for kinases that are not recommended for use with Kinase Tracer 236, such as PIM3, CDC42BPG, MAP2K7, TXK, and SIK3. BODIPY-FL staurosporine can be a powerful tool for analyzing kinase selectivity in kinase drug discovery .

Cat. No.	Product Name	Target	Research Area

HY-P10042A

S6K Substrate acetate	Ribosomal S6 Kinase (RSK)	Others
S6K Substrate acetate is a substrate for active protein kinases, including CLK2, MRCKalpha, MRCKbeta, p70S6K, ROCK1, ROCK2, RSK1, RSK3, PIM1 .

HY-P1404

R8-T198wt	Pim	Cancer
R8-T198wt is a cell-permeable carboxyl-terminal p27 ^Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase .

HY-P10042

S6K Substrate	Ribosomal S6 Kinase (RSK)	Others
S6K Substrate is a substrate for active protein kinases, including CLK2, MRCKalpha, MRCKbeta, p70S6K, ROCK1, ROCK2, RSK1, RSK3, PIM1 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1950

Hispidulin 4 Publications Verification Dinatin	Structural Classification Flavonoids Classification of Application Fields Flavones Labiatae Source classification Cassia Phenols Polyphenols Plants Disease Research Fields Cancer	Pim
Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC₅₀ of 2.71 μM.

HY-N4149

Quercetagetin 3 Publications Verification 6-Hydroxyquercetin	Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Eriocaulon L. Phenols Polyphenols Eriocaulaceae Plants Inflammation/Immunology Disease Research Fields	Pim
Quercetagetin (6-Hydroxyquercetin) is a flavonoid . Quercetagetin is a moderately potent and selective, cell-permeable *pim-1* kinase inhibitor (IC₅₀, 0.34 μM) . Anti-inflammatory and anticancer properties.

HY-N1950R

Hispidulin (Standard) Dinatin (Standard)	Structural Classification Flavonoids Classification of Application Fields Labiatae Source classification Cassia Phenols Plants Disease Research Fields Cancer	Reference Standards Pim
Hispidulin (Standard) is the analytical standard of Hispidulin. This product is intended for research and analytical applications. Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC₅₀ of 2.71 μM.

HY-N4149R

Quercetagetin (Standard) 6-Hydroxyquercetin (Standard)	Flavonols Structural Classification Flavonoids Source classification Eriocaulon L. Phenols Polyphenols Eriocaulaceae Plants	Reference Standards Pim
Quercetagetin (Standard) is the analytical standard of Quercetagetin. This product is intended for research and analytical applications. Quercetagetin (6-Hydroxyquercetin) is a flavonoid . Quercetagetin is a moderately potent and selective, cell-permeable pim-1 kinase inhibitor (IC50, 0.34 μM) . Anti-inflammatory and anticancer properties.

Species:	Human (4)
Tag:	His (1) Tag Free (2) GST (1)
Source:	Sf9 insect cells (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P701745

	PIM1 Protein, Human 1 Publications Verification Pim1; Serine/threonine-protein kinase Pim-1	Human	E. coli
	The PIM1 protein is a proto-oncogene with serine/threonine kinase activity that significantly promotes cell survival and proliferation, providing a selective advantage for tumorigenesis. It regulates MYC transcription, cell cycle progression, and inhibits pro-apoptotic proteins such as BAD, MAP3K5, and FOXO3 through phosphorylation. PIM1 Protein, Human is the recombinant human-derived PIM1 protein, expressed by E. coli , with tag free.

HY-P701746

	PIM2 Protein, Human Pim2; Serine/threonine-protein kinase Pim-2; Pim-2h	Human	E. coli
	The PIM2 protein is a proto-oncogene with serine/threonine kinase activity that critically promotes cell survival and proliferation through multiple mechanisms. It enhances MYC stability and transcriptional activity, explaining the synergistic effect in tumorigenesis. PIM2 Protein, Human is the recombinant human-derived PIM2 protein, expressed by E. coli , with tag free.

HY-P701747

	PIM2 Protein, Human (His) Pim2; Serine/threonine-protein kinase Pim-2; Pim-2h	Human	E. coli
	The PIM2 protein is a proto-oncogene with serine/threonine kinase activity that critically promotes cell survival and proliferation through multiple mechanisms. It enhances MYC stability and transcriptional activity, explaining the synergistic effect in tumorigenesis. PIM2 Protein, Human (His) is the recombinant human-derived PIM2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701749

	PIM3 Protein, Human (sf9, GST) Pim3; Serine/threonine-protein kinase Pim-3	Human	Sf9 insect cells
	The PIM3 protein is a serine/threonine kinase proto-oncogene that is crucial in preventing apoptosis, promoting cell survival, and protein translation in underlying tumorigenesis. It phosphorylates BAD, releases anti-apoptotic Bcl-X(L) and affects cell cycle, protein synthesis and MYC transcriptional activity, showing multifaceted effects on tumorigenesis. PIM3 Protein, Human (sf9, GST) is the recombinant human-derived PIM3 protein, expressed by sf9 insect cells , with N-GST labeled tag.

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HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83005

	PIM2 Antibody (YA2750) Pim2; Serine/threonine-protein kinase Pim-2; Pim-2h	WB, ICC/IF, IP	Human, Mouse, Rat
	PIM2 Antibody (YA2750) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2750), targeting PIM2, with a predicted molecular weight of 34 kDa (observed band size: 37 kDa). PIM2 Antibody (YA2750) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

HY-P82757

	PIM1 Antibody (YA2502) Pim1; Serine/threonine-protein kinase Pim-1	WB, IHC-P	Human
	PIM1 Antibody (YA2502) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2502), targeting PIM1, with a predicted molecular weight of 36 kDa (observed band size: 36 kDa). PIM1 Antibody (YA2502) can be used for WB, IHC-P experiment in human background.