1. JAK/STAT Signaling Cell Cycle/DNA Damage Stem Cell/Wnt PI3K/Akt/mTOR Protein Tyrosine Kinase/RTK
  2. Pim CDK GSK-3 Src
  3. Protein kinase inhibitor 11

Protein kinase inhibitor 11 (Compound I-96) is a protein kinase inhibitor that can inhibit the activity of PIM-1, CDK-2, GSK-3, and SRC. Protein kinase inhibitor 11 holds promise for research in cancer, immune disorders, and neurodegenerative diseases.

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Protein kinase inhibitor 11

Protein kinase inhibitor 11 Chemical Structure

CAS No. : 721964-51-8

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Based on 1 publication(s) in Google Scholar

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Description

Protein kinase inhibitor 11 (Compound I-96) is a protein kinase inhibitor that can inhibit the activity of PIM-1, CDK-2, GSK-3, and SRC. Protein kinase inhibitor 11 holds promise for research in cancer, immune disorders, and neurodegenerative diseases[1].

Molecular Weight

423.46

Formula

C21H18FN5O2S

CAS No.
SMILES

O=C(CSC1=NN2C(C=C1)=NN=C2C3=CC=C(OCC)C=C3)NC4=CC=C(C=C4)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 4.17 mg/mL (9.85 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3615 mL 11.8075 mL 23.6150 mL
5 mM 0.4723 mL 2.3615 mL 4.7230 mL
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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3615 mL 11.8075 mL 23.6150 mL 59.0375 mL
5 mM 0.4723 mL 2.3615 mL 4.7230 mL 11.8075 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Protein kinase inhibitor 11
Cat. No.:
HY-W844558
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