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IX

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106087
    IX 207-887

    		Interleukin Related Inflammation/Immunology
    IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).
    IX 207-887
  • HY-107412
    Proteasome inhibitor IX

    PS-IX; AM114

    		 Proteasome Cancer
    Proteasome inhibitor IX (PS-IX; AM114) is a Chalcone derivative and a chymotrypsin-like activity of the 20S proteasome inhibitor with an IC50 value of ~1 μM. Proteasome inhibitor IX exhibits HCT116 p53 +/+ cells growth inhibitory activity with an IC50 value of 1.49 μM. Proteasome inhibitor IX has potent anticancer activity .
    Proteasome inhibitor IX
  • HY-136476G
    Pt(II) protoporphyrin IX

    		Drug Intermediate Others
    Pt(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Pt(II) protoporphyrin IX
  • HY-402723
    hCAVII/IX-IN-1

    		Carbonic Anhydrase Cancer
    hCAVII/IX-IN-1 (compound 4) is a hCAVII/IX inhibitor, with Ki values ​​of 56.5 nM and 38.2 nM, respectively. hCAVII/IX-IN-1 can be used in anticancer research .
    hCAVII/IX-IN-1
  • HY-149011
    CA IX-IN-1

    		Carbonic Anhydrase Cancer
    CA IX-IN-1 (compound 12g) is an effective and selective inhibitor of hCA IX with IC50 value of 7 nM. CA IX-IN-1 exhibits antitumor activity .
    CA IX-IN-1
  • HY-112935
    Nonacog alfa

    BAX326; Coagulation Factor IX [Recombinant]; BeneFIX

    		 Ser/Thr Protease Others
    Nonacog alfa (BAX326) is a recombinant human factor IX that can be used for the research of haemophilia B .
    Nonacog alfa
  • HY-168767
    CA IX-IN-3

    		Carbonic Anhydrase Others
    CA IX-IN-3 (Compound 27) is a selective and potent carbonic anhydrase IX (CA IX) inhibitor with an IC50 of 0.48 nM .
    CA IX-IN-3
  • HY-W504836
    Deuteroporphyrin IX dihydrochloride

    		Photosensitizer Neurological Disease
    Deuteroporphyrin IX (dihydrochloride) is a photosensitizer with high lipophilicity and amphiphilicity, capable of providing photosensitivity for cell membrane systems. Deuteroporphyrin IX (dihydrochloride) can induce irreversible discharge elimination in individual neurons .
    Deuteroporphyrin IX dihydrochloride
  • HY-136476F
    Cd(II) protoporphyrin IX

    		Drug Intermediate Others
    Cd(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Cd(II) protoporphyrin IX
  • HY-136476E
    Cr(III) protoporphyrin IX

    		Drug Intermediate Others
    Cr(III) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Cr(III) protoporphyrin IX
  • HY-B1247R
    Protoporphyrin IX (Standard)

    		Endogenous Metabolite Others
    Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
    Protoporphyrin IX (Standard)
  • HY-P5771
    Jingzhaotoxin-IX

    		Sodium Channel Neurological Disease
    Jingzhaotoxin-IX, a C-terminally amidated peptide composed of 35 amino acid residues, is a neurotoxin. Jingzhaotoxin-IX inhibits voltage-gated sodium channels (both tetrodotoxin-resistant and tetrodotoxin-sensitive isoforms) and Kv2.1 channel. Jingzhaotoxin-IX has no effect on delayed rectifier potassium channel Kv1.1, 1.2 and 1.3 .
    Jingzhaotoxin-IX
  • HY-B1247
    Protoporphyrin IX
    15+ Cited Publications

    		 Endogenous Metabolite Others
    Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
    Protoporphyrin IX
  • HY-W854721
    Mn(III) Protoporphyrin IX chloride

    Manganese(III) Protoporphyrin IX Chloride

    		 Heme Oxygenase (HO) Metabolic Disease
    Mn(III) protoporphyrin IX chloride is a metalloporphyrin. It induces mRNA expression of the genes encoding δ-aminolevulinate synthase and heme oxygenase (HO), enzymes that catalyze the rate-limiting steps of heme biosynthesis and degradation, respectively, in chick embryo liver cells when used at a concentration of 10 μM. Mn(III) protoporphyrin IX chloride-containing nanobialys have been used in magnetic resonance imaging (MRI) of fibrin clots in vitro. It has also been used in the synthesis of Mn(III) protoporphyrin IX-6(7)-glycyl-glycyl-L-histidine methyl ester (MnGGH), a metalloporphyrin conjugate with microperoxidase activity.
    Mn(III) Protoporphyrin IX chloride
  • HY-136476
    Mg(II) protoporphyrin IX

    		Others Others
    Mg(II) protoporphyrin IX is a precursor of chlorophyll in Chlorella. Mg(II) protoporphyrin IX is a negative effector of nuclear photosynthetic gene expression. Mg(II) protoporphyrin IX can be used for the research of signaling molecule implicated in plastid-to-nucleus communication .
    Mg(II) protoporphyrin IX
  • HY-133821
    N-Methylmesoporphyrin IX

    		G-quadruplex Neurological Disease
    N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies .
    N-Methylmesoporphyrin IX
  • HY-W073074
    Mesoporphyrin IX dihydrochloride

    		VSV Infection
    Mesoporphyrin IX (dihydrochloride) is a photosensitizer that can be used to modify liposomes. Mesoporphyrin IX (dihydrochloride) can insert into lipid vesicles and disrupt the viral membrane structure in vesicular stomatitis virus (VSV), inducing cross-linking of VSV glycoproteins, thereby inhibiting viral activity .
    Mesoporphyrin IX dihydrochloride
  • HY-W250116
    Co(III) protoporphyrin IX chloride

    Protoporphyrin IX cobaltic chloride

    		 Biochemical Assay Reagents Others
    Co(III) Protoporphyrin IX chloride (CoPP) is an effective HO-1inducer.
    Co(III) protoporphyrin IX chloride
  • HY-E70541B
    Canine Factor IX

    		Biochemical Assay Reagents Cardiovascular Disease
    Canine Factor IX is prepared from freshly collected canine plasma. Factor IX activated by the Factor VIIa/tissue factor/phospholipid complex is responsible for the activation of Factor X to Factor Xa .
    Canine Factor IX
  • HY-E70541A
    Bovine Factor IX

    		Biochemical Assay Reagents Cardiovascular Disease
    Bovine Factor IX is prepared from freshly collected bovine plasma. Factor IX activated by the Factor VIIa/tissue factor/phospholipid complex is responsible for the activation of Factor X to Factor Xa .
    Bovine Factor IX
  • HY-136476A
    Mn(II) protoporphyrin IX

    		Biochemical Assay Reagents Others
    Mn(II) protoporphyrin IX is a potential intravenous paramagnetic magnetic resonance contrast agent. Mn(II) protoporphyrin IX maintains strong paramagnetic properties .
    Mn(II) protoporphyrin IX
  • HY-B1247A
    Protoporphyrin IX disodium
    15+ Cited Publications

    		 Endogenous Metabolite Cancer
    Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
    Protoporphyrin IX disodium
  • HY-101194
    Tin protoporphyrin IX dichloride
    15+ Cited Publications

    Tin-protoporphyrin IX; Sn-Protoporphyrin; SnPPIX

    		 Reactive Oxygen Species Cancer
    Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model .
    Tin protoporphyrin IX dichloride
  • HY-133235
    Baccatin IX

    		Others Others
    Baccatin IX is a Diterpenoids product that can be isolated from the twigs and leaves of Taxus yunnanensis. .
    Baccatin IX
  • HY-129430
    N-Methylprotoporphyrin IX

    		Drug Derivative Ferrochelatase Others
    N-Methylprotoporphyrin IX is a potent inhibitor of ferrochelatase enzyme .
    N-Methylprotoporphyrin IX
  • HY-P10714
    Ub4ix

    		Proteasome Apoptosis Deubiquitinase Cancer
    Ub4ix is a DUB/26S proteasome inhibitor. Ub4ix can protect K48-linked Ub chains from being chopped up by deubiquitinating enzymes (DUBs) and prevent the proteasomal degradation of Ub-tagged proteins. Ub4ix can reduce the viability of Hela cells and induce apoptosis, with an IC50 value of 1.6 μM .
    Ub4ix
  • HY-N12251
    Gymnoside IX

    		Others Others
    Gymnoside IX (compound 2) can be isolated from the methanolic extract from the tubers of Gymnadenia conopsea .
    Gymnoside IX
  • HY-159122
    CA IX-IN-2

    		Carbonic Anhydrase Reactive Oxygen Species Apoptosis Cancer
    CA IX-IN-2 (Compound 9o) is an inhibitor for carbonic anhydrase (CA), that inhibits CA IX, CA XII and CA II with an IC50 of 5.6, 7.4 and 430 nM, respectively. CA IX-IN-2 inhibits the proliferation of cancer cell HCT-116, SW480, MDA-MB 231 and MCF-7, with IC50s of 14.63-29.33 μM. CA IX-IN-2 intercalates DNA, arrests cell cycle at G1/S phase, and induces apoptosis in MDA-MB-231. CA IX-IN-2 affects the mitochondrial membrane potential (MMP), increases the intracellular ROS levels, causes mitochondrial damage, and inhibits the cell migration of MDA-MB-231. CA IX-IN-2 exhibits antitumor efficacy in mouse models .
    CA IX-IN-2
  • HY-168855
    hCAII/IX-IN-1

    		Carbonic Anhydrase Cancer
    hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with the Kis of 7.4 and 7.0 nM, respectively. hCAII/IX-IN-1 plays an important role in cancer research .
    hCAII/IX-IN-1
  • HY-W587082
    Cr(III) Mesoporphyrin IX chloride

    		Biochemical Assay Reagents Others
    Cr(III) Mesoporphyrin IX chloride is a biochemical assay reagent.
    Cr(III) Mesoporphyrin IX chloride
  • HY-134608
    Cobalt protoporphyrin IX

    Co-PPIX

    		 Reactive Oxygen Species Influenza Virus Infection
    Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV) .
    Cobalt protoporphyrin IX
  • HY-W127786
    Hematoporphyrin IX dimethyl ester

    		Biochemical Assay Reagents Others
    Hematoporphyrin IX dimethyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Hematoporphyrin IX dimethyl ester
  • HY-158328A
    CA IX/VEGFR-2-IN-2

    		Carbonic Anhydrase VEGFR Reactive Oxygen Species MDM-2/p53 Bcl-2 Family Cytochrome P450 Caspase Cancer
    CA IX/VEGFR-2-IN-2 (compound 5e) is a dual-targeted inhibitor. CA IX/VEGFR-2-IN-2 shows strong inhibitory effects on both CA IX (Ki=3.1 μM) and VEGFR-2 (IC50=32.1 nM). CA IX/VEGFR-2-IN-2 can be used for the study of pancreatic (PANC1), breast cancer (MCF7) and prostate cancer (PC3) .
    CA IX/VEGFR-2-IN-2
  • HY-W072979
    Mesoporphyrin dimethyl ester

    Mesoporphyrin IX dimethyl ester

    		 Biochemical Assay Reagents
    Mesoporphyrin dimethyl ester (Mesoporphyrin IX dimethyl ester) is a biochemical reagent .
    Mesoporphyrin dimethyl ester
  • HY-147799
    hCA XII/II/IX-IN-1

    		Carbonic Anhydrase Cancer
    hCA XII/II/IX-IN-1 (Compound 3) is a potent human carbonic anhydrase (hCA) inhibitor with IC50 values of 2.6, 0.004, 0.005 and 0.001 μM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA XII/II/IX-IN-1 shows anticancer activity .
    hCA XII/II/IX-IN-1
  • HY-W583212
    Zn(II) Mesoporphyrin IX

    ZnMP

    		 Biochemical Assay Reagents Inflammation/Immunology
    Zn(II) Mesoporphyrin IX (ZnMP) is a specific activator of ABCB10, significantly increasing its ATPase activity and acting as a substrate for ABCB10 in heme synthesis. Zn(II) Mesoporphyrin IX may promote the transcription of hemoglobinization genes by facilitating the degradation of the Bach1 repressor. Zn(II) Mesoporphyrin IX aids in studying the potential roles of ABCB10 in heme synthesis, oxidative stress protection, hepatitis C, and other areas .
    Zn(II) Mesoporphyrin IX
  • HY-170551
    CA IX/VEGFR-2-IN-3

    		Carbonic Anhydrase VEGFR Cancer
    CA IX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. CA IX/VEGFR-2-IN-3 exhibits anticancer activity, inhibiting the growth of MCF-7 breast cancer cells (with an IC50 of 22.33 μM) and mouse fibroblast cell line 3T3 (where cell viability is less than 40% at a concentration of 100 μM). CA IX/VEGFR-2-IN-3 can be used for research in the field of cancer treatment .
    CA IX/VEGFR-2-IN-3
  • HY-W127816
    Cr(III) Protoporphyrin IX chloride

    		Biochemical Assay Reagents Others
    Cr(III) Protoporphyrin IX Chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Cr(III) Protoporphyrin IX chloride
  • HY-W127815
    Pd(II) Mesoporphyrin IX

    		Biochemical Assay Reagents Others
    Pd(II) Mesoporphyrin IX is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Pd(II) Mesoporphyrin IX
  • HY-136476C
    Ni(II) protoporphyrin IX

    		Biochemical Assay Reagents Ferrochelatase Others
    Ni(II) protoporphyrin IX is a metalloporphyrin that has a low tendency toward axial ligation, becomes distorted when bound to ferrochelatase .
    Ni(II) protoporphyrin IX
  • HY-NP114
    Highly purified Type IX collagen, from chick articular cartilage

    Chick Type IX collagen, immunization grade

    		 MMP Inflammation/Immunology
    Highly purified Type IX collagen, from chick articular cartilage (Chick Type IX collagen, immunization grade) is an immune grade collagen derived from chick articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type IX collagen, from chick articular cartilage
  • HY-NP105
    Highly purified Type IX collagen, from bovine articular cartilage

    Bovine Type IX collagen, immunization grade

    		 MMP Inflammation/Immunology
    Highly purified Type IX collagen, from bovine articular cartilage (Bovine Type IX collagen, immunization grade) is an immune grade collagen derived from bovine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type IX collagen, from bovine articular cartilage
  • HY-NP125
    Highly purified Type IX collagen, from porcine articular cartilage

    Porcine Type IX collagen, immunization grade

    		 MMP Inflammation/Immunology
    Highly purified Type IX collagen, from porcine articular cartilage (Porcine Type IX collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type IX collagen, from porcine articular cartilage
  • HY-W555382
    Pseudane IX

    2-Nonylquinolin-4(1H)-one

    		 HCV Infection
    Pseudane IX, a compound isolated from the leaves of Ruta angustifolia, has strong anti-HCV activity with an IC50 value of 1.4 μg/mL. Pseudane IX reduces HCV RNA replication and viral protein synthesis levels .
    Pseudane IX
  • HY-B0754A
    Hematoporphyrin dihydrochloride
    10+ Cited Publications

    Hematoporphyrin IX dihydrochloride

    		 Apoptosis Endogenous Metabolite Cancer
    Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin dihydrochloride can induce apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light .
    Hematoporphyrin dihydrochloride
  • HY-B0754
    Hematoporphyrin

    Hematoporphyrin IX

    		 Apoptosis Endogenous Metabolite Cancer
    Hematoporphyrin (Hematoporphyrin IX), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin can induce apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light .
    Hematoporphyrin
  • HY-E70427
    Dipeptidyl peptidase IX (human)

    		Biochemical Assay Reagents Others
    Dipeptidyl peptidase IX (human) is a hydrolase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .
    Dipeptidyl peptidase IX (human)
  • HY-15281
    QL-IX-55

    		mTOR Cancer
    QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively.
    QL-IX-55
  • HY-W127788
    2,4-Diacetyl deuteroporphyrin IX dimethyl ester

    		Biochemical Assay Reagents Others
    2,4-Diacetyl deuteroporphyrin IX dimethyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    2,4-Diacetyl deuteroporphyrin IX dimethyl ester
  • HY-W555382S
    Pseudane IX-d4

    2-Nonylquinolin-4(1H)-one-d4

    		 Isotope-Labeled Compounds HCV Infection
    Pseudane IX-d4 (2-Nonylquinolin-4(1H)-one-d4) is deuterium labeled Pseudane IX. Pseudane IX, a compound isolated from the leaves of Ruta angustifolia, has strong anti-HCV activity with an IC50 value of 1.4 μg/mL. Pseudane IX reduces HCV RNA replication and viral protein synthesis levels .
    Pseudane IX-d4

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