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HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast, colon, and lung cancers .
HB-230 is a red fluorescent transglutaminase 2 (TG2) probe. HB-230 complexes with TG2 and α2-macroglobulin via the LRP1 pathway for efficient endocytosis. The excitation and emission wavelengths of HB-230 are 649 and 665 nm, respectively .
HB-107 is a peptide with wound healing properties. HB-107 promotes the proliferation of keratinocytes and increased leukocyte infiltration at the wound site, and it also stimulates cultured endothelial cells to secrete interleukin 8 (IL-8). HB-107 holds potential for research in the fields of wound healing and inflammation .
HB-0017 is a humanized IgG1κ monoclonal antibody inhibitor, targeting IL-17A. HB-0017 inhibits the IL-6 secretion induced by IL-17A with an IC50 of 2.09 nM. HB-0017 significantly decreases ear thickness in Imiquimod (HY-B0180)-induced psoriasis-like mice model and alleviates inflammations in IL-17A-induced arthritis and air pouch mice model. The isotype control for the HB-0017 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001) .
Hb 98-114, the amino acids 98-114 of the alpha subunit of bovine hemoglobin, is an antimicrobial peptide. Hb 98-114 is active against several yeast and filamentous fungi (MIC: 2.1 μM-12.5 μM) .
3,3'-Diindolylmethane (Standard) is the analytical standard of 3,3'-Diindolylmethane. This product is intended for research and analytical applications. 3,3'-Diindolylmethane is a strong, pure androgen receptor (AR) antagonist.
P4hb Mouse Pre-designed siRNA Set A contains three designed siRNAs for P4hb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
P4hb Rat Pre-designed siRNA Set A contains three designed siRNAs for P4hb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
P4HB Human Pre-designed siRNA Set A contains three designed siRNAs for P4HB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) is a kind of mouse IgG2a kappa in vivo mouse antibody, targeting to influenza virus nucleoprotein. The recommend isotype control of Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)): Mouse IgG2a kappa, Isotype Control (HY-P99978).
CV-4-26 (Compound 22) is a covalent inhibitor of TEAD. CV-4-26 inhibits YAP/TEAD-based transcription, leading to the reduction of CTGF and CYR61 expression. CV-4-26 inhibits Huh7 and HepG2 cell colony formation, induces cell cycle arrest, and apoptosis. CV-4-26 shows antitumor activity against hepatocellular carcinoma (HCC) and hepatoblastoma (HB) .
1-Methylisatin is a potent and selective CE (carboxylesterases) inhibitor, with Kis of 38.2 and 5.38 μM for hiCE and hCE1, respectively. 1-Methylisatin interacts with Hb (human adult hemoglobin) by hydrophobic binding and electrostatic attraction. 1-Methylisatin can be used in the study of regulation of agent metabolism in vivo .
N-Formylsarcolysine has antitumor activity, and inhibits leukemia by increasing the Hb and erythrocyte levels and decreasing the number of leukocytes. N-Formylsarcolysine also involves in glioblastoma and other diseases research .
Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
Efaproxiral sodium (RSR13 sodium) is a synthetic allosteric modifier of haemoglobin (Hb), decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy.
Efaproxiral-d6 is the deuterium labeled Efaproxiral. Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
Efaproxiral (Standard) is the analytical standard of Efaproxiral. This product is intended for research and analytical applications. Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
NVP-SAA164 is an orally active nonpeptide kinin B1 receptor antagonist. NVP-SAA164 reverses CFA (Complete Freund's adjuvant) (HY-153808)-induced mechanical hyperalgesia and desArg10KD-induced hyperalgesia in hB1-KI mice, and is inactive in a model of inflammatory pain in wild-type mice .
Antimicrobial agent-29 (Compound C35) affects the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore. Antimicrobial agent-29 helps the discovery of IsdB:Hb PPI inhibitors .
3-Methoxyphenol is a phenolic compound that is biologically toxic. 3-Methoxyphenol is systemically absorbed, disrupts the function of the liver, kidneys, central nervous system, and redox processes, and increases levels of Hb, red blood cells, and white blood cells in the body.
Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine (HY-17589A) sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC50s of 0.9 nM and 20.8 nM, respectively .
PF-07059013 is an orally active and potent noncovalent modulator of sickled hemoglobin (HbS). PF-07059013 specifically binds to Hb with nanomolar affinity and displays strong partitioning into red blood cells (RBCs). PF-07059013 can be used for sickle cell disease (SCD) research .
Methyl acetimidate is an imidoester that can inhibit the formation of sickle cells. Methyl acetimidate enhances the oxygen affinity and gelling properties of high molecular weight hemoglobin (HMW Hb) by modifying the amino groups of hemoglobin, thereby suppressing the formation of sickle cells. Methyl acetimidate can be used in research related to anemia .
3-Methoxyphenol (Standard) is the analytical standard of 3-Methoxyphenol. This product is intended for research and analytical applications. 3-Methoxyphenol is a phenolic compound that is biologically toxic. 3-Methoxyphenol is systemically absorbed, disrupts the function of the liver, kidneys, central nervous system, and redox processes, and increases levels of Hb, red blood cells, and white blood cells in the body.
3-Methoxyphenol-d3 is deuterated labeled 3-Methoxyphenol (HY-Y1840). 3-Methoxyphenol is a phenolic compound that is biologically toxic. 3-Methoxyphenol is systemically absorbed, disrupts the function of the liver, kidneys, central nervous system, and redox processes, and increases levels of Hb, red blood cells, and white blood cells in the body.
Ksr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ksr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
EK1 is a peptide-based fusion inhibitor of coronaviruses (CoVs) with broad spectrum inhibition to a number of CoV species. EK1 shows substantially improved pan-CoV fusion inhibitory activity. EK1 potently inhibits SARS-CoV-2. EK1 can form a stable six-helix bundle (6HB) structure with both short α-hCoV and long β-hCoV N-terminal heptad repeats .
Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model .
GSTM1 Human Pre-designed siRNA Set A contains three designed siRNAs for GSTM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RO6889678 is a highly potent HBV capsid formation inhibitor with a complex absorption, distribution, metabolism, and excretion (ADME) profile. RO6889678 is a potent inducer of CYP3A4 and coregulated proteins in human hepatocytes. RO6889678 is metabolized by a combination of CYP3A4-mediated oxidation and UDP-glucuronosyltransferase UGT1A3- and UGT1A1-mediated direct glucuronidation .
HB-107 is a peptide with wound healing properties. HB-107 promotes the proliferation of keratinocytes and increased leukocyte infiltration at the wound site, and it also stimulates cultured endothelial cells to secrete interleukin 8 (IL-8). HB-107 holds potential for research in the fields of wound healing and inflammation .
Hb 98-114, the amino acids 98-114 of the alpha subunit of bovine hemoglobin, is an antimicrobial peptide. Hb 98-114 is active against several yeast and filamentous fungi (MIC: 2.1 μM-12.5 μM) .
EK1 is a peptide-based fusion inhibitor of coronaviruses (CoVs) with broad spectrum inhibition to a number of CoV species. EK1 shows substantially improved pan-CoV fusion inhibitory activity. EK1 potently inhibits SARS-CoV-2. EK1 can form a stable six-helix bundle (6HB) structure with both short α-hCoV and long β-hCoV N-terminal heptad repeats .
This enzyme is a DNA ligase cloned from Thermus aquaticus HB8. It is expressed in E. coli using genetic recombination technology and purified and isolated multiple times.
Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) is a kind of mouse IgG2a kappa in vivo mouse antibody, targeting to influenza virus nucleoprotein. The recommend isotype control of Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)): Mouse IgG2a kappa, Isotype Control (HY-P99978).
HB-0017 is a humanized IgG1κ monoclonal antibody inhibitor, targeting IL-17A. HB-0017 inhibits the IL-6 secretion induced by IL-17A with an IC50 of 2.09 nM. HB-0017 significantly decreases ear thickness in Imiquimod (HY-B0180)-induced psoriasis-like mice model and alleviates inflammations in IL-17A-induced arthritis and air pouch mice model. The isotype control for the HB-0017 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001) .
Anti-Mouse CD1d Antibody (20H2 (HB323)) is a kind of rat IgG1 kappa in vivo mouse antibody, targeting to CD1d. The recommend isotype control of Anti-Mouse CD1d Antibody (20H2 (HB323)): Rat IgG1 kappa, Isotype Control (HY-P99979).
Anti-Mouse T15 VH and T15 VL regions of IgM Antibody (HB33) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to mouse T15 VH and T15 VL regions of IgM.
3,3'-Diindolylmethane (Standard) is the analytical standard of 3,3'-Diindolylmethane. This product is intended for research and analytical applications. 3,3'-Diindolylmethane is a strong, pure androgen receptor (AR) antagonist.
Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model .
HB-EGF protein is a multifunctional growth factor that is regulated through EGFR, ERBB2 and ERBB4 and is critical for cardiac valve formation and cardiac function. It promotes smooth muscle cell proliferation and may contribute to macrophage-mediated cell proliferation. HB-EGF Protein, Human (HEK293, His) is the recombinant human-derived HB-EGF protein, expressed by HEK293 , with C-6*His labeled tag.
P4HB proteins are versatile and multifunctional, coordinating disulfide bond catalysis at the cell surface and inside the cell.It exhibits reductase activity, cleaves disulfide bonds, induces structural modifications, and functions as a chaperone to inhibit aggregation of misfolded proteins.P4HB Protein, Mouse (HEK293, His) is the recombinant mouse-derived P4HB protein, expressed by HEK293 , with C-His labeled tag.
The P4HB protein is a multifunctional entity that catalyzes disulfide bonding processes at the cell surface and within cells. As a reductase, it modifies outer surface proteins and participates in the formation of disulfide bonds in nascent proteins. P4HB Protein, Human (HEK293, His) is the recombinant human-derived P4HB protein, expressed by HEK293 , with C-6*His labeled tag.
The P4HB protein is a multifunctional entity that catalyzes disulfide bonding processes at the cell surface and within cells. As a reductase, it modifies outer surface proteins and participates in the formation of disulfide bonds in nascent proteins. P4HB Protein, Human (His) is the recombinant human-derived P4HB protein, expressed by E. coli , with N-6*His labeled tag.
The ATF2 protein is a transcriptional activator that regulates anti-apoptotic genes, cell growth, and DNA damage responses. It binds to CRE and AP-1 sequences and plays a key role in nuclear transcription. ATF2 Protein, Human (sf9, His-GST) is the recombinant human-derived ATF2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
ALCAM/CD166 protein is a multifunctional cell adhesion molecule involved in various cell-cell interactions. It promotes T cell activation and immune synapse formation by interacting with CD6. ALCAM/CD166 Protein, Rat (HEK293, Fc) is the recombinant rat-derived ALCAM/CD166 protein, expressed by HEK293 , with C-hFc labeled tag.
HB-EGF protein is a multifunctional growth factor that is regulated through EGFR, ERBB2 and ERBB4 and is critical for cardiac valve formation and cardiac function. It promotes smooth muscle cell proliferation and may contribute to macrophage-mediated cell proliferation. HB-EGF Protein, Human (sf9) is the recombinant human-derived HB-EGF protein, expressed by Sf9 insect cells , with tag free.
ALCAM/CD166 protein is a multifunctional cell adhesion molecule involved in various cell-cell interactions. It promotes T cell activation and immune synapse formation by interacting with CD6. ALCAM/CD166 Protein, Rat (HEK293, His) is the recombinant rat-derived ALCAM/CD166 protein, expressed by HEK293 , with C-His labeled tag.
Pleiotrophin (PTN) is a secreted growth factor that transduces signals through cell surface proteoglycan and non-proteoglycan receptors.PTN binds to chondroitin sulfate (CS) groups and regulates cell proliferation, survival, and differentiation, particularly inhibiting long-term synaptic potentiation of neurons.Pleiotrophin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Pleiotrophin protein, expressed by HEK293 , with N-hFc labeled tag.
Pleiotrophin is a secreted growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors to influence a variety of cellular processes. It binds to chondroitin sulfate (CS) groups, regulates proliferation, survival and differentiation, and inhibits long-term synaptic potentiation of neurons. Pleiotrophin Protein, Human is the recombinant human-derived Pleiotrophin protein, expressed by E. coli , with tag free. The total length of Pleiotrophin Protein, Human is 136 a.a., with molecular weight of ~15.3 kDa.
Pleiotrophin is a secreted growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors to influence a variety of cellular processes. It binds to chondroitin sulfate (CS) groups, regulates proliferation, survival and differentiation, and inhibits long-term synaptic potentiation of neurons. Animal-Free Pleiotrophin Protein, Human (His) is the recombinant human-derived animal-FreePleiotrophin protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.
Efaproxiral-d6 is the deuterium labeled Efaproxiral. Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
3-Methoxyphenol-d3 is deuterated labeled 3-Methoxyphenol (HY-Y1840). 3-Methoxyphenol is a phenolic compound that is biologically toxic. 3-Methoxyphenol is systemically absorbed, disrupts the function of the liver, kidneys, central nervous system, and redox processes, and increases levels of Hb, red blood cells, and white blood cells in the body.
HBEGF Antibody (YA1801) is a non-conjugated IgG antibody, targeting HBEGF, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). HBEGF Antibody (YA1801) can be used for WB experiment in human, rat background.
P4HB Antibody (YA1503) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1503), targeting P4HB, with a predicted molecular weight of 57 kDa (observed band size: 57 kDa). P4HB Antibody (YA1503) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human, mouse, rat background.
VPS26 Antibody (YA1546) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1546), targeting VPS26, with a predicted molecular weight of 38 kDa (observed band size: 38 kDa). VPS26 Antibody (YA1546) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.
HB9; HLXB9; Homeobox HB9; Homeobox protein HB9; HOXHB9; MNX1; Motor neuron and pancreas homeobox protein 1; SCRA1
WB, IP
Human, Mouse
HB9 Antibody (YA2415) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2415), targeting HB9, with a predicted molecular weight of 41 kDa (observed band size: 41 kDa). HB9 Antibody (YA2415) can be used for WB, IP experiment in human, mouse background.
HBEGF Antibody (YA4641) is a non-conjugated IgG antibody, targeting HBEGF, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). HBEGF Antibody (YA4641) can be used for WB experiment in human, rat, mouse background.
P4HB Antibody (YA3681) is a mouse-derived and non-conjugated IgG2a antibody, targeting to P4HB. It can be applicated for WB, IHC-P, FC, ELISA assays, in the background of human.
P4HB Antibody (YA3682) is a mouse-derived and non-conjugated IgG2a antibody, targeting to P4HB. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human.
Gamma 1 globin; Gamma 2 globin; Gamma A hemoglobin; Gamma globin; HB F Agamma; HB F Ggamma; HBG1; HBG2; HBGA; HBGR
WB
Human
Fetal Hemoglobin Antibody (YA2564) is a non-conjugated IgG antibody, targeting Fetal Hemoglobin, with a predicted molecular weight of 16 kDa (observed band size: 12 kDa). Fetal Hemoglobin Antibody (YA2564) can be used for WB experiment in human background.
NR5A2 Antibody (YA2472) is a non-conjugated IgG antibody, targeting NR5A2, with a predicted molecular weight of 61 kDa (observed band size: 65 kDa). NR5A2 Antibody (YA2472) can be used for WB experiment in human, mouse, rat background.
PEG10 Antibody (YA1277) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1277), targeting PEG10. PEG10 Antibody (YA1277) can be used for IHC-P experiment in human background.
HLX; HLX1; H2.0-like homeobox protein; Homeobox protein HB24; Homeobox protein HLX1
WB
Human, Mouse, Rat, Bovine, Dog, Pig
HLX1 Antibody (YA5126) is a mouse-derived and non-conjugated monoclonal antibody, targeting to HLX1. It can be applicated for WB assays, in the background of human, mouse, rat, bovine, dog, pig.
CD83; CD83 antigen; hCD83; B-cell activation protein; Cell surface protein HB15; CD antigen CD83
WB
Human, Mouse, Rat
CD83 Antibody (YA2260) is a non-conjugated IgG antibody, targeting CD83, with a predicted molecular weight of 23 kDa (observed band size: 45 kDa). CD83 Antibody (YA2260) can be used for WB experiment in human, mouse, rat background.
GSTM1 Antibody (YA2308) is a non-conjugated IgG antibody, targeting GSTM1, with a predicted molecular weight of 26 kDa (observed band size: 26 kDa). GSTM1 Antibody (YA2308) can be used for WB experiment in human, mouse, rat background.
Glutathione S Transferase mu 1 Antibody (YA2928) is a non-conjugated IgG antibody, targeting Glutathione S Transferase mu 1, with a predicted molecular weight of 26 kDa (observed band size: 26 kDa). Glutathione S Transferase mu 1 Antibody (YA2928) can be used for WB experiment in human, hamster background.
PEG10 Antibody (YA5265) is a mouse-derived and non-conjugated monoclonal antibody, targeting to PEG10. It can be applicated for WB, IP assays, in the background of human.
PTN Antibody (YA1773) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1773), targeting PTN, with a predicted molecular weight of 19 kDa (observed band size: 19 kDa). PTN Antibody (YA1773) can be used for WB, IP experiment in human, rat background.
ATF2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 52 kDa, targeting to ATF2. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.
Glutathione S Transferase mu; glutathione-S-transferase; Glutathione S Transferase; Glutathione S transferase Mu 1; GST 26; GST class mu 1; GST1; GSTM1; GSTM1 1; GSTM1a 1a; GSTM1b 1b; GTH4; GTM1; H B; HB subunit 4; MGC26563; MU 1; MU; SJ26 antigen; SjGST; GST-tag.
WB
Mouse, Species independent
GST tag Antibody (YA6375) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GST tag. It can be applicated for WB assays, in the background of mouse, species independent.
P4hb Mouse Pre-designed siRNA Set A contains three designed siRNAs for P4hb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
P4hb Rat Pre-designed siRNA Set A contains three designed siRNAs for P4hb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
P4HB Human Pre-designed siRNA Set A contains three designed siRNAs for P4HB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Ksr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ksr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
GSTM1 Human Pre-designed siRNA Set A contains three designed siRNAs for GSTM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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