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Results for "

H19

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Biochemical Assay Reagents

4

Recombinant Proteins

1

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-113238A
    Lithocholic acid 3-sulfate disodium

    Sulfolithocholic acid disodium; LCAS disodium

    		 GPR39 Others Inflammation/Immunology
    Lithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 41  and 42.4 (absence of Zn 2+) and 0.88 and 0.97 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Lithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Lithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
    Lithocholic acid 3-sulfate disodium
  • HY-137255
    Taurolithocholic acid 3-sulfate disodium

    3-Sulfotaurolithocholic acid disodium

    		 GPR39 Inflammation/Immunology
    Taurolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 71.6  and 69.4 (absence of Zn 2+) and 9 and 9.6 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Taurolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Taurolithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
    Taurolithocholic acid 3-sulfate disodium
  • HY-W587430
    Glycolithocholic acid 3-sulfate disodium

    Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium

    		 HIV GPR39 Infection Inflammation/Immunology
    Glycolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 47.9  and 66.8 μM (absence of Zn 2+) and 8 and 8.7 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Glycolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Glycolithocholic acid 3-sulfate disodium also inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate disodium can be used for the research of HIV infection and gallbladder disease .
    Glycolithocholic acid 3-sulfate disodium
  • HY-RS16353
    H19 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    H19 Human Pre-designed siRNA Set A contains three designed siRNAs for H19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    H19 Human Pre-designed siRNA Set A
    H19 Human Pre-designed siRNA Set A
  • HY-173080
    Antibacterial agent 267

    		Bacterial Infection
    Antibacterial agent 267 (Compound h19) is a pleuromutilin derivative with a potent antibacterial activity on Gram-positive bacteria. Antibacterial agent 267 shows an antibacterial activity in methicillin-resistant Staphylococcus aureus (MRSA)-infected mouse models .
    Antibacterial agent 267
  • HY-159119
    hDHODH-IN-15

    		Dihydroorotate Dehydrogenase Ferroptosis Cancer
    hDHODH-IN-15 (Compound H19) is an inhibitor for human dihydroguanylate dehydrogenase (hDHODH) with an IC50 of 0.21 µM. hDHODH-IN-15 exhibits cytotoxicity in cancer cells NCI-H226, HCT-116, and MDA-MB-231, with IC50 of 0.95-2.81 µM. hDHODH-IN-15 induces ferroptosis in HCT-116, and exhibits antitumor efficacy .
    hDHODH-IN-15

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