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Results for "

DMF

" in MedChemExpress (MCE) Product Catalog:

28

Inhibitors & Agonists

5

Fluorescent Dye

8

Natural
Products

2

Isotope-Labeled Compounds

1

Click Chemistry

7

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W098689

    2'-Deoxy-N2-dimethylaminomethylene-guanosine

    Nucleoside Antimetabolite/Analog Others
    Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a deoxyguanosine (dG) nucleoside protected by the dimethylaminomethylamidine (DMF) base and can be used for oligonucleotide synthesis .
    Dmf-dg
  • HY-Y1078

    N-Dimethoxymethyl-N,N-dimethylamine

    Biochemical Assay Reagents Others
    1,1-Dimethoxy-N,N-dimethylmethanamine (N-Dimethoxymethyl-N,N-dimethylamine) is a biological molecule.
    DMF-DMA
  • HY-155786

    TGF-beta/Smad Others
    3,7-DMF is an orally active inhibitor of TGF-β1-induced activation of HSCs. 3,7-DMF induces antioxidant genes and quenches ROS away, which can be used to study liver fibrosis .
    3,7-DMF
  • HY-138585

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection Cancer
    DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer that can be used in the preparation of oligonucleotides
    DMT-dG(dmf) Phosphoramidite
  • HY-W087919

    Others Others
    5-Methyl-2-furanmethanol is a natural product that can be isolated from the essential oil of D. rupicola Biv.. 5-Methyl-2-furanmethanol also acts as a oxidative product of 2,5 dimethylfuran (DMF) by cytochrome P450 (CYP) .
    5-Methyl-2-furanmethanol
  • HY-103252
    Monomethyl fumarate
    5 Publications Verification

    GPR109A Drug Metabolite Neurological Disease Inflammation/Immunology
    Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease .
    Monomethyl fumarate
  • HY-147320

    DNA/RNA Synthesis Others
    3'-DMTr-dG(dmf) is a guanosine derivative used in the synthesis of nucleic acids .
    3'-DMTr-dG(dmf)
  • HY-W141393

    DNA/RNA Synthesis Others
    2'-OMe-dmf-G-CE-Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
    2'-OMe-dmf-G-CE-Phosphoramidite
  • HY-W087919R

    Others Others
    5-Methyl-2-furanmethanol (Standard) is the analytical standard of 5-Methyl-2-furanmethanol. This product is intended for research and analytical applications. 5-Methyl-2-furanmethanol is a natural product that can be isolated from the essential oil of D. rupicola Biv.. 5-Methyl-2-furanmethanol also acts as a oxidative product of 2,5 dimethylfuran (DMF) by cytochrome P450 (CYP)[1][2].
    5-Methyl-2-furanmethanol (Standard)
  • HY-103252R

    GPR109A Drug Metabolite Neurological Disease Inflammation/Immunology
    Monomethyl fumarate (Standard) is the analytical standard of Monomethyl fumarate. This product is intended for research and analytical applications. Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease[1][2][3].
    Monomethyl fumarate (Standard)
  • HY-100375
    Diroximel fumarate
    3 Publications Verification

    ALKS 8700; BIIB098

    Keap1-Nrf2 Inflammation/Immunology
    Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity .
    Diroximel fumarate
  • HY-138607

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection Cancer
    5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
    5'-O-DMT-N2-DMF-dG
  • HY-43066

    DNA/RNA Synthesis Others
    (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-(((E)-(dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
    DMT-2'-O-TBDMS-G(dmf)-CE-phosphoramidite
  • HY-D2231

    ADC Cytotoxin Others
    Cy3.5 maleimide is a relatively water-soluble fluorescent dye. Cy3.5 maleimide is soluble in organic solvents, including DMF, DMSO and acetonitrile and so on .
    Cy3.5 maleimide
  • HY-W048502

    8-Thioadenosine

    Drug Intermediate Others
    8-Mercaptoadenosine is a nucleoside derivative that can be synthesized in DMF-aqueous solution at room temperature using NaSH via the corresponding 8-bromo compounds, and it is an intermediate in the synthesis of the substrate for RNA pyrophosphorylase .
    8-Mercaptoadenosine
  • HY-103252S1

    Isotope-Labeled Compounds GPR109A Drug Metabolite Neurological Disease Inflammation/Immunology
    Monomethyl fumarate-d5 is deuterium labeled Monomethyl fumarate. Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease .
    Monomethyl fumarate-d5
  • HY-W998687

    Fluorescent Dye Others
    Cy5 dimethyl is a free non-activated dye. This dye has limited water solubility, but can be dissolved in mixtures of water with organic phase (DMF, DMSO, alcohols) to obtain useful concentrations of the material in solution. This molecule can be considered non-reactive dye for the use in control samples, and for instrument calibration.
    Cy5 dimethyl
  • HY-W015883
    Fumaric acid
    2 Publications Verification

    Endogenous Metabolite NF-κB p38 MAPK Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
    Fumaric acid
  • HY-W015883R

    Endogenous Metabolite NF-κB p38 MAPK Metabolic Disease Inflammation/Immunology
    Fumaric acid (Standard) is the analytical standard of Fumaric acid. This product is intended for research and analytical applications. Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
    Fumaric acid (Standard)
  • HY-17363
    Dimethyl fumarate
    Maximum Cited Publications
    37 Publications Verification

    Keap1-Nrf2 Reactive Oxygen Species HIV Autophagy Endogenous Metabolite Infection Neurological Disease Inflammation/Immunology Cancer
    Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .
    Dimethyl fumarate
  • HY-17363S1

    Autophagy HIV Keap1-Nrf2 Endogenous Metabolite Reactive Oxygen Species Cancer
    Dimethyl fumarate-d2 is the deuterium labeled Dimethyl fumarate . Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .
    Dimethyl fumarate-d2
  • HY-17363R

    Keap1-Nrf2 Reactive Oxygen Species HIV Autophagy Endogenous Metabolite Infection Neurological Disease Inflammation/Immunology Cancer
    Dimethyl fumarate (Standard) is the analytical standard of Dimethyl fumarate. This product is intended for research and analytical applications. Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .
    Dimethyl fumarate (Standard)
  • HY-D0819
    CY5-SE
    15+ Cited Publications

    Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester

    Fluorescent Dye Others
    Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.
    CY5-SE
  • HY-131030

    JF669, SE; JF669, NHS

    Fluorescent Dye Others
    Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 669, SE
  • HY-164480

    IKK NF-κB Inflammation/Immunology Cancer
    GTCpFE inhibits IKKα/β in the NF-κB pathway with anti-inflammatory activities and blocks p65 nuclear entry, which consists of Dimethyl fumarate (DMF) (HY-17363) linked to Aspirin (ASA) (HY-14654). GTCpFE exhibits selective anti-cancer stem-like cell (CSC) activity by reducing mammosphere growth and the CD44 + CD24 - immunophenotype. GTCpFE inhibits breast cancer stem cells, an important NFκB- and PGE2-dependent phenotype in aggressive cancers .
    GTCpFE
  • HY-D2759

    Fluorescent Dye Others
    Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction. Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength. This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.
    Cyanine3B azide
  • HY-Y0543
    5-Methylfurfural
    1 Publications Verification

    Biochemical Assay Reagents COX Inflammation/Immunology Cancer
    5-Methylfurfural is a chemical that can be utilized as food additive, intermediate in the production of agrochemicals, and precursor of certain anti-cancer natural products. 5-Methylfurfural is formed during the photoexposition of ranitidine hydrochloride. 5-Methylfurfural is an organic compound. 5-Methylfurfural has a strong tendency to be further hydrogenated to 2,5-dimethylfuran (DMF). 5-Methylfurfural can predominantly evoke skin inflammation and barrier disintegration. 5-Methylfurfural degrades native DNA through the formation of single-strand breaks .
    5-Methylfurfural
  • HY-Y0543R

    Biochemical Assay Reagents Reference Standards COX Inflammation/Immunology Cancer
    5-Methylfurfural (Standard) is the analytical standard of 5-Methylfurfural. This product is intended for research and analytical applications. 5-Methylfurfural is a chemical that can be utilized as food additive, intermediate in the production of agrochemicals, and precursor of certain anti-cancer natural products. 5-Methylfurfural is formed during the photoexposition of ranitidine hydrochloride. 5-Methylfurfural is an organic compound. 5-Methylfurfural has a strong tendency to be further hydrogenated to 2,5-dimethylfuran (DMF). 5-Methylfurfural can predominantly evoke skin inflammation and barrier disintegration. 5-Methylfurfural degrades native DNA through the formation of single-strand breaks .
    5-Methylfurfural (Standard)

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