Search Result

Results for "

CRF2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CFTR (5) CRFR (19) Small Interfering RNA (siRNA) (8)
By Research Areas:	Cardiovascular Disease (4) Endocrinology (10) Metabolic Disease (4) Neurological Disease (13)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (6) siRNAs (8)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1752B

Urocortin II, human acetate	CRFR	Metabolic Disease Endocrinology
Urocortin II, human (acetate) is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor. For investigating the role of the CRF (2) receptor in ingestive behavior .

HY-RS03171

CRHR2 Human Pre-designed siRNA Set A CRF2; CRFR2; CRF-RB; HM-CRF	Small Interfering RNA (siRNA)	Others
CRHR2 Human Pre-designed siRNA Set A contains three designed siRNAs for CRHR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CRHR2 Human Pre-designed siRNA Set A CRHR2 Human Pre-designed siRNA Set A

HY-RS06738

IL22RA2 Human Pre-designed siRNA Set A CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2; ZCYTOR16; IL-22R-alpha-2	Small Interfering RNA (siRNA)	Others
IL22RA2 Human Pre-designed siRNA Set A contains three designed siRNAs for IL22RA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL22RA2 Human Pre-designed siRNA Set A IL22RA2 Human Pre-designed siRNA Set A

HY-RS18866

Ifnlr1 Mouse Pre-designed siRNA Set A Il28ra; CRF2-12	Small Interfering RNA (siRNA)	Others
Ifnlr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ifnlr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ifnlr1 Mouse Pre-designed siRNA Set A Ifnlr1 Mouse Pre-designed siRNA Set A

HY-RS06737

IL22RA1 Human Pre-designed siRNA Set A IL22R; CRF2-9; IL22R1	Small Interfering RNA (siRNA)	Others
IL22RA1 Human Pre-designed siRNA Set A contains three designed siRNAs for IL22RA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL22RA1 Human Pre-designed siRNA Set A IL22RA1 Human Pre-designed siRNA Set A

HY-RS06595

IFNLR1 Human Pre-designed siRNA Set A IFNLR; LICR2; IL28RA; CRF2/12; IL-28R1	Small Interfering RNA (siRNA)	Others
IFNLR1 Human Pre-designed siRNA Set A contains three designed siRNAs for IFNLR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IFNLR1 Human Pre-designed siRNA Set A IFNLR1 Human Pre-designed siRNA Set A

HY-RS03173

Crhr2 Rat Pre-designed siRNA Set A CRF2r; CRF-R 2; CRH-R 2	Small Interfering RNA (siRNA)	Others
Crhr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Crhr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Crhr2 Rat Pre-designed siRNA Set A Crhr2 Rat Pre-designed siRNA Set A

HY-RS06732

IL20RA Human Pre-designed siRNA Set A CRF2-8; IL-20R1; IL-20RA; IL-20R-alpha	Small Interfering RNA (siRNA)	Others
IL20RA Human Pre-designed siRNA Set A contains three designed siRNAs for IL20RA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL20RA Human Pre-designed siRNA Set A IL20RA Human Pre-designed siRNA Set A

HY-RS06674

IL10RB Human Pre-designed siRNA Set A CRFB4; IBD25; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2; IL-10RB	Small Interfering RNA (siRNA)	Others
IL10RB Human Pre-designed siRNA Set A contains three designed siRNAs for IL10RB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL10RB Human Pre-designed siRNA Set A IL10RB Human Pre-designed siRNA Set A

HY-P1108

Astressin 2B	CFTR	Others
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for *CRF2* and *CRF1, respectively. Astressin 2B antagonizes CRF2*-mediated inhibition of gastric emptying ^[2] .

HY-P1108A

Astressin 2B TFA	CFTR	Others
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for *CRF2* and *CRF1, respectively. Astressin 2B TFA antagonizes CRF2*-mediated inhibition of gastric emptying ^[2] .

HY-P1106A

K41498 TFA	CFTR	Cardiovascular Disease
K41498 TFA is a potent and highly selective *CRF2 receptor* antagonist with K_i values of 0.66 nM, 0.62 nM and 425 nM for human CRF_2α, CRF_2β and CRF₁ receptors respectively. K41498 TFA is an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF_2α- and hCRF_2β-expressing cells. K41498 TFA can be used for hypotension study .

HY-P1294

*α-Helical CRF(9-41)*	CRFR	Neurological Disease
α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with K_B of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC₅₀ of 140 nM ^[2].

HY-P1294A

*α-Helical CRF(9-41) TFA*	CRFR	Neurological Disease
α-Helical CRF(9-41) TFA is a competitive CRF2 receptor antagonist with K_B of ~100 nM. α-Helical CRF(9-41) TFA is also a partial agonist of CRF1 receptor with an EC₅₀ of 140 nM ^[2].

HY-P3597

Urocortin III (mouse) (free acid)	CFTR	Others
Urocortin III (mouse) (free acid) is a selective CRF2 receptor agonist (with high affinity for the *CRF2* receptor). Urocortin III (mouse) (free acid) significantly inhibits gastric emptying without modifying colonic transit ^[2].

HY-P1752

Urocortin II, human	CRFR	Metabolic Disease Endocrinology
Urocortin II (human) is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor. For investigating the role of the CRF (2) receptor in ingestive behavior .

HY-P1752A

Urocortin II, human TFA	CRFR	Metabolic Disease Endocrinology
Urocortin II, human (TFA) is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor. For investigating the role of the CRF (2) receptor in ingestive behavior .

HY-P1107

Antisauvagine-30 1 Publications Verification aSvg-30	CRFR	Neurological Disease
Antisauvagine-30 (aSvg-30) is a potent, competitive and selective CRF₂ receptor antagonist with K_d values of 1.4 nM and 153.6 nM for mouse CRF_2β and rat CRF₁ receptors, respectively .

HY-14875

Verucerfont GSK561679	CRFR	Neurological Disease Endocrinology
Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC₅₀s of ~6.1, >1000 and >1000?nM for CRF1, CRF2, and CRF-BP, respectively.

HY-P2847

Urocortin II, mouse	CRFR	Metabolic Disease Endocrinology
Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with K_i values of 0.66 nM and ﹥100 nM for CRFR2 and CRFR1, respectively. Urocortin II, mouse activates CRF2 receptors in a cAMP/PKA- and Ca ²⁺/CaMKII-dependent manner.Urocortin II, mouse is expressed in discrete areas of the central nervous system, and activates central neurons involved in the processing of visceral sensory information, and in modulating autonomic outflow ^[2] .

HY-P1295

Urocortin, human Urocortin (human); Human urocortin; Human urocortin 1; Human urocortin I	CRFR	Neurological Disease Endocrinology
Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF₂ receptor, with K_is of 0.4, 0.3, and 0.5 nM for hCRF₁, rCRF_2α and mCRF_2β, respectively.

HY-P1106

K41498	CRFR	Cardiovascular Disease
K41498 is a potent and highly selective *CRF2 receptor* antagonist with K_i values of 0.66 nM, 0.62 nM and 425 nM for human CRF_2α, CRF_2β and CRF₁ receptors respectively. K41498 is an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF_2α- and hCRF_2β-expressing cells. K41498 can be used for hypotension study .

HY-12129

CP 154526 hydrochloride	CFTR	Neurological Disease
CP 154526 hydrochloride is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K_i of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (K_i = >10 μM). CP 154526 hydrochloride has anxiolytic activities ^[2].

HY-12130

CP 154526	CRFR	Neurological Disease
CP 154526 is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K_i of 2.7 nM. CP 154526 shows selective for CRF1 over CRF2 (K_i = >10 μM). CP 154526 has anxiolytic activities ^[2].

HY-P1107A

Antisauvagine-30 TFA 1 Publications Verification aSvg-30 TFA	CRFR	Neurological Disease
Antisauvagine-30 TFA (aSvg-30 TFA) is a potent, highly selective and competitive CRF₂ receptor peptidic antagonist. Antisauvagine-30 TFA exhibits a K_d of 1.4 nM and 150 nM for mCRFR2β and CRFR1, respectively ^[2] .

HY-P1542

Urotensin I Catostomus urotensin I	CRFR	Cardiovascular Disease Endocrinology
Urotensin I (Catostomus urotensin I), a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC₅₀s of 11.46, 9.36 and 9.85 for human CRF₁, human CRF₂ and rat CRF_2α receptors in CHO cells, and K_is of 0.4, 1.8, and 5.7 nM for hCRF₁, rCRF_2α and mCRF_2β receptors, respectively ^[2].

HY-14128

NBI-34041 SB-723620	CRFR	Neurological Disease
NBI-34041 (SB-723620) is a selective and orally active nonpeptide CRF1 receptor antagonist with an IC₅₀ of 58.9 nM and a K_i of 4.0 nM for human CRF1 receptor. NBI-34041 has no inhibitory effect on the CRF2 receptor. NBI-34041 can be used for depression and anxiety disorders research.

HY-P1542B

Urotensin I TFA Catostomus urotensin I TFA	CRFR	Cardiovascular Disease Endocrinology
Urotensin I (Catostomus urotensin I) TFA, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC₅₀s of 11.46, 9.36 and 9.85 for human CRF₁, human CRF₂ and rat CRF_2α receptors in CHO cells, and K_is of 0.4, 1.8, and 5.7 nM for hCRF₁, rCRF_2α and mCRF_2β receptors, respectively ^[2].

HY-110056

NBI 35965 hydrochloride	CRFR	Neurological Disease
NBI 35965 hydrochloride is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K_i value of 4 nM and a pK_i value of 8.5. NBI 35965 hydrochloride does not inhibit CRF2. NBI 35965 hydrochloride reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC₅₀ values of 7.1 and 6.9, respectively. NBI 35965 hydrochloride shows anxiolytic effects ^[2].

HY-103378

NBI 35965 methanesulfonate	CRFR	Neurological Disease
NBI 35965 methanesulfonate is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K_i value of 4 nM and a pK_i value of 8.5. NBI 35965 methanesulfonate does not inhibit CRF2. NBI 35965 methanesulfonate reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC₅₀ values of 7.1 and 6.9, respectively. NBI 35965 methanesulfonate shows anxiolytic effects ^[2].

HY-P1296

Urocortin, rat Urocortin (Rattus norvegicus); Rat urocortin	CRFR	Neurological Disease Endocrinology
Urocortin, rat (Urocortin (Rattus norvegicus)) is a neuropeptide and a potent endogenous CRFR agonist with K_is of 13 nM, 1.5 nM, and 0.97 nM for human CRF₁, rat CRF_2α and mouse CRF_2β, respectively ^[2].

HY-P1296A

Urocortin, rat TFA Urocortin (Rattus norvegicus) (TFA); Rat urocortin TFA	CRFR	Neurological Disease Endocrinology
Urocortin, rat TFA (Urocortin (Rattus norvegicus) TFA) is a neuropeptide and a potent endogenous CRFR agonist with K_is of 13 nM, 1.5 nM, and 0.97 nM for human CRF₁, rat CRF_2α and mouse CRF_2β, respectively ^[2].

Cat. No.	Product Name	Target	Research Area

HY-P1752B

Urocortin II, human acetate	CRFR	Metabolic Disease Endocrinology
Urocortin II, human (acetate) is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor. For investigating the role of the CRF (2) receptor in ingestive behavior .

HY-P1108A

Astressin 2B TFA	CFTR	Others
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for *CRF2* and *CRF1, respectively. Astressin 2B TFA antagonizes CRF2*-mediated inhibition of gastric emptying ^[2] .

HY-P1106A

K41498 TFA	CFTR	Cardiovascular Disease
K41498 TFA is a potent and highly selective *CRF2 receptor* antagonist with K_i values of 0.66 nM, 0.62 nM and 425 nM for human CRF_2α, CRF_2β and CRF₁ receptors respectively. K41498 TFA is an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF_2α- and hCRF_2β-expressing cells. K41498 TFA can be used for hypotension study .

HY-P1294

*α-Helical CRF(9-41)*	CRFR	Neurological Disease
α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with K_B of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC₅₀ of 140 nM ^[2].

HY-P1294A

*α-Helical CRF(9-41) TFA*	CRFR	Neurological Disease
α-Helical CRF(9-41) TFA is a competitive CRF2 receptor antagonist with K_B of ~100 nM. α-Helical CRF(9-41) TFA is also a partial agonist of CRF1 receptor with an EC₅₀ of 140 nM ^[2].

HY-P1752

Urocortin II, human	CRFR	Metabolic Disease Endocrinology
Urocortin II (human) is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor. For investigating the role of the CRF (2) receptor in ingestive behavior .

HY-P2847

Urocortin II, mouse	CRFR	Metabolic Disease Endocrinology
Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with K_i values of 0.66 nM and ﹥100 nM for CRFR2 and CRFR1, respectively. Urocortin II, mouse activates CRF2 receptors in a cAMP/PKA- and Ca ²⁺/CaMKII-dependent manner.Urocortin II, mouse is expressed in discrete areas of the central nervous system, and activates central neurons involved in the processing of visceral sensory information, and in modulating autonomic outflow ^[2] .

HY-P1108

Astressin 2B	CFTR	Others
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for *CRF2* and *CRF1, respectively. Astressin 2B antagonizes CRF2*-mediated inhibition of gastric emptying ^[2] .

HY-P3597

Urocortin III (mouse) (free acid)	CFTR	Others
Urocortin III (mouse) (free acid) is a selective CRF2 receptor agonist (with high affinity for the *CRF2* receptor). Urocortin III (mouse) (free acid) significantly inhibits gastric emptying without modifying colonic transit ^[2].

HY-P1752A

Urocortin II, human TFA	CRFR	Metabolic Disease Endocrinology
Urocortin II, human (TFA) is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor. For investigating the role of the CRF (2) receptor in ingestive behavior .

HY-P1295

Urocortin, human Urocortin (human); Human urocortin; Human urocortin 1; Human urocortin I	CRFR	Neurological Disease Endocrinology
Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF₂ receptor, with K_is of 0.4, 0.3, and 0.5 nM for hCRF₁, rCRF_2α and mCRF_2β, respectively.

HY-P1106

K41498	CRFR	Cardiovascular Disease
K41498 is a potent and highly selective *CRF2 receptor* antagonist with K_i values of 0.66 nM, 0.62 nM and 425 nM for human CRF_2α, CRF_2β and CRF₁ receptors respectively. K41498 is an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF_2α- and hCRF_2β-expressing cells. K41498 can be used for hypotension study .

HY-P1542

Urotensin I Catostomus urotensin I	CRFR	Cardiovascular Disease Endocrinology
Urotensin I (Catostomus urotensin I), a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC₅₀s of 11.46, 9.36 and 9.85 for human CRF₁, human CRF₂ and rat CRF_2α receptors in CHO cells, and K_is of 0.4, 1.8, and 5.7 nM for hCRF₁, rCRF_2α and mCRF_2β receptors, respectively ^[2].

HY-P1542B

Urotensin I TFA Catostomus urotensin I TFA	CRFR	Cardiovascular Disease Endocrinology
Urotensin I (Catostomus urotensin I) TFA, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC₅₀s of 11.46, 9.36 and 9.85 for human CRF₁, human CRF₂ and rat CRF_2α receptors in CHO cells, and K_is of 0.4, 1.8, and 5.7 nM for hCRF₁, rCRF_2α and mCRF_2β receptors, respectively ^[2].

HY-P1296

Urocortin, rat Urocortin (Rattus norvegicus); Rat urocortin	CRFR	Neurological Disease Endocrinology
Urocortin, rat (Urocortin (Rattus norvegicus)) is a neuropeptide and a potent endogenous CRFR agonist with K_is of 13 nM, 1.5 nM, and 0.97 nM for human CRF₁, rat CRF_2α and mouse CRF_2β, respectively ^[2].

HY-P1296A

Urocortin, rat TFA Urocortin (Rattus norvegicus) (TFA); Rat urocortin TFA	CRFR	Neurological Disease Endocrinology
Urocortin, rat TFA (Urocortin (Rattus norvegicus) TFA) is a neuropeptide and a potent endogenous CRFR agonist with K_is of 13 nM, 1.5 nM, and 0.97 nM for human CRF₁, rat CRF_2α and mouse CRF_2β, respectively ^[2].

Species:	Human (13) Mouse (6) Rat (3) Cat (1) Cynomolgus (3) Pig (1) Canine (2)
Tag:	His (17) Tag Free (2) Avi (4) Fc (12)
Source:	HEK293 (27) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P72557

	IL-22BP/IL-22RA2 Protein, Human (HEK293, His) Interleukin-22 receptor subunit alpha-2; IL-22RA2; CRF2-10; CRF2-S1; IL-22BP; ZcytoR16	Human	HEK293
	IL-22BP/IL-22RA2 proteins (especially isoform 2) act as IL22 receptors and antagonists, inhibiting IL22 activity by preventing its interaction with functional IL-22R complexes in vitro. This regulatory effect suggests its potential in modulating inflammatory responses. IL-22BP/IL-22RA2 Protein, Human (HEK293, His) is the recombinant human-derived IL-22BP/IL-22RA2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73154

	IL-10 Protein, Pig 1 Publications Verification Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b	Pig	E. coli
	IL-10 Protein, a key immune regulator, mitigates inflammation by binding to its receptor (IL10RA/IL10RB), activating JAK1 and STAT2, leading to STAT3-mediated anti-inflammatory gene expression. IL-10 targets APCs, reducing pro-inflammatory cytokines and hindering antigen presentation. It controls macrophage inflammation through metabolic reprogramming. Existing as a homodimer, IL-10 interacts with IL10RA/IL10RB. IL-10 Protein, Pig is the recombinant pig-derived IL-10 protein, expressed by E. coli , with tag free.

HY-P73152

	IL-10 Protein, Feline Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b	Cat	E. coli
	IL-10 Protein, a key immune regulator, mitigates inflammation by binding to its receptor (IL10RA/IL10RB), activating JAK1 and STAT2, leading to STAT3-mediated anti-inflammatory gene expression. IL-10 targets APCs, reducing pro-inflammatory cytokines and hindering antigen presentation. It controls macrophage inflammation through metabolic reprogramming. Existing as a homodimer, IL-10 interacts with IL10RA/IL10RB. IL-10 Protein, Feline is the recombinant IL-10 protein, expressed by E. coli , with tag free.

HY-P73153

	IL-10 Protein, Human (HEK293, His) Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b	Human	HEK293
	IL-10 protein is a major immunoregulatory cytokine with profound anti-inflammatory functions that limits excessive tissue destruction caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptors IL10RA and IL10RB, leading to JAK1- and STAT2-mediated phosphorylation of STAT3, which translocates to the nucleus and drives the expression of anti-inflammatory mediators. IL-10 Protein, Human (HEK293, His) is the recombinant human-derived IL-10 protein, expressed by HEK293 , with N-His labeled tag.

HY-P72599

	IL-10R beta Protein, Human (HEK293, His) Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b	Human	HEK293
	IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses.IL-10R beta Protein, Human (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (W221-F242) with a 6*His tag at the C-terminus.

HY-P74837

	IL-10R beta Protein, Mouse (HEK293, His) Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b	Mouse	HEK293
	IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses. IL-10R beta Protein, Mouse (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (W223-Y251) with a His tag at the C-terminus.

HY-P76414

	IL-10R beta Protein, Rat (HEK293, Fc) Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b	Rat	HEK293
	IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses.IL-10R beta Protein, Rat (HEK293, Fc) is expressed by HEK 293 cells and consists of 351 amino acids (M1-V351) with a Fc tag at the C-terminus.

HY-P75854

	IL-22BP/IL-22RA2 Protein, Human (HEK293, Fc) Interleukin-22 receptor subunit alpha-2; IL-22RA2; CRF2-10; CRF2-S1; IL-22BP; ZcytoR16	Human	HEK293
	IL-22BP/IL-22RA2 proteins (especially isoform 2) act as IL22 receptors and antagonists, inhibiting IL22 activity by preventing its interaction with functional IL-22R complexes in vitro. This regulatory effect suggests its potential in modulating inflammatory responses. IL-22BP/IL-22RA2 Protein, Human (HEK293, Fc) is the recombinant human-derived IL-22BP/IL-22RA2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75855

	IL-22BP/IL-22RA2 Protein, Human (HEK293, His-Fc) Interleukin-22 receptor subunit alpha-2; IL-22RA2; CRF2-10; CRF2-S1; IL-22BP; ZcytoR16	Human	HEK293
	IL-22BP/IL-22RA2 proteins (especially isoform 2) act as IL22 receptors and antagonists, inhibiting IL22 activity by preventing its interaction with functional IL-22R complexes in vitro. This regulatory effect suggests its potential in modulating inflammatory responses. IL-22BP/IL-22RA2 Protein, Human (HEK293, His-Fc) is the recombinant human-derived IL-22BP/IL-22RA2 protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

HY-P74838

	IL-10R beta Protein, Mouse (HEK293, hFc) Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b	Mouse	HEK293
	IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses. IL-10R beta Protein, Mouse (HEK293, hFc) is expressed by HEK 293 cells and has a transmembrane region (W223-Y251) with a hFc tag at the C-terminus.

HY-P77965

	IL-20R alpha Protein, Mouse (HEK293, Fc) IL-20R-alpha; IL-20RA; CRF2-8; IL-20R1; ZcytoR7; FLJ40993	Mouse	HEK293
	IL-20R alpha Protein (IL20RA) is the alpha subunit of IL-20 receptor, forms functional heterodimers with different subunit protein and involves in STAT3 activation pathway. The IL20RA/IL20RB dimer is a receptor for IL-19, IL-20 and IL-24, while the IL20RA/IL10RB dimer is a receptor for IL-26. IL-20R alpha Protein is consists of 553 amino acids (M1-N553) with a transmembrane domain (254-274 a.a.). IL-20R alpha Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal His-tag.

HY-P74839

	IL-10R beta Protein, Human (HEK293, His-hFc) Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b	Human	HEK293
	IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses. IL-10R beta Protein, Human (HEK293, His-hFc) is expressed by HEK293 cells and with a His and -hFc tag at the C-terminus.

HY-P72562

	IL-20R alpha Protein, Human (HEK293, His) Interleukin-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; CRF2-8; IL-20R1; ZcytoR7	Human	HEK293
	IL-20R alpha Protein (IL20RA) is the alpha subunit of IL-20 receptor, forms functional heterodimers with different subunit protein and involves in STAT3 activation pathway. The IL20RA/IL20RB dimer is a receptor for IL-19, IL-20 and IL-24, while the IL20RA/IL10RB dimer is a receptor for IL-26. IL-20R alpha Protein is consists of 553 amino acids (M1-N553) with a transmembrane domain (251-271 a.a.). IL-20R alpha Protein, Human (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag.

HY-P77419

	IL-20R alpha Protein, Human (HEK293, Fc) Interleukin-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; CRF2-8; IL-20R1; ZcytoR7	Human	HEK293
	IL-20R alpha Protein (IL20RA) is the alpha subunit of IL-20 receptor, forms functional heterodimers with different subunit protein and involves in STAT3 activation pathway. The IL20RA/IL20RB dimer is a receptor for IL-19, IL-20 and IL-24, while the IL20RA/IL10RB dimer is a receptor for IL-26. IL-20R alpha Protein is consists of 553 amino acids (M1-N553) with a transmembrane domain (251-271 a.a.). IL-20R alpha Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal hFc-tag.

HY-P77001

	IL-22R alpha 1 Protein, Rat (HEK293, Fc) Interleukin-22 receptor subunit alpha-1; IL-22R-alpha-1; CRF2-9; ZcytoR11; IL22R	Rat	HEK293
	IL-22R alpha 1 (IL22RA1) Protein is an IL-22 receptor. IL-22R alpha 1 Protein interacts with IL-22 to activate the JAK/STAT cascade thereby inhibits IL-22 mediated promotion of cell proliferation and anti-apoptosis. IL-22R alpha 1 Protein, Rat (HEK293, Fc) is expressed by HEK 293 cells and has a transmembrane region (M1-A228) with a Fc tag at the C-terminus.

HY-P77002

	IL-22R alpha 1 Protein, Rat (HEK293, His) Interleukin-22 receptor subunit alpha-1; IL-22R-alpha-1; CRF2-9; ZcytoR11; IL22R	Rat	HEK293
	IL-22R alpha 1 (IL22RA1) Protein is an IL-22 receptor. IL-22R alpha 1 Protein interacts with IL-22 to activate the JAK/STAT cascade thereby inhibits IL-22 mediated promotion of cell proliferation and anti-apoptosis. IL-22R alpha 1 Protein, Rat (HEK293, His) is expressed by HEK 293 cells, with a His tag at the C-terminus.

HY-P77423

	IL-22R alpha 1 Protein, Canine (HEK293, Fc) Interleukin-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22RA1; CRF2-9; ZcytoR11; IL22R	Canine	HEK293
	IL-22R alpha 1 (IL22RA1) Protein is an IL-22 receptor. IL-22R alpha 1 Protein interacts with IL-22 to activate the JAK/STAT cascade thereby inhibits IL-22 mediated promotion of cell proliferation and anti-apoptosis. IL-22R alpha 1 Protein, Canine (HEK293, Fc) is expressed by HEK 293 cells and with a Fc tag at the C-terminus.

HY-P77424

	IL-22R alpha 1 Protein, Canine (HEK293, His) Interleukin-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22RA1; CRF2-9; ZcytoR11; IL22R	Canine	HEK293
	IL-22R alpha 1 (IL22RA1) Protein is an IL-22 receptor. IL-22R alpha 1 Protein interacts with IL-22 to activate the JAK/STAT cascade thereby inhibits IL-22 mediated promotion of cell proliferation and anti-apoptosis. IL-22R alpha 1 Protein, Canine (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (M1-The226) with a His tag at the C-terminus.

HY-P78308

	IFNAR1 Protein, Mouse (HEK293, Fc) AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1	Mouse	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Mouse (HEK293, Fc) is a recombinant mouse IFNAR1 (E27-T429) with C-terminal hFc tag, which is produced in HEK293 cells.

HY-P77967

	IL-22R alpha 1 Protein, Human (HEK293, Fc) IL-22R-alpha-1; IL-22RA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11	Human	HEK293
	IL-22R alpha 1 (IL22RA1) Protein is an IL-22 receptor. IL-22R alpha 1 Protein interacts with IL-22 to activate the JAK/STAT cascade thereby inhibits IL-22 mediated promotion of cell proliferation and anti-apoptosis. IL-22R alpha 1 Protein, Human (HEK293, Fc) is expressed by HEK 293 cells and has a transmembrane region (H16-T228) with a Fc tag at the C-terminus.

HY-P77969

	IL-22R alpha 1 Protein, Mouse (HEK293, Fc) 1 Publications Verification IL-22R-alpha-1; IL-22RA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11	Mouse	HEK293
	IL-22R α 1 and IL-10R β together form IL20, IL22 and IL24 receptor complexes, activating different signaling pathways. Within the IL22 receptor, IL-22R α 1 binds to IL10RB and mediates IL22 signaling through the JAK/STAT and MAPK1/MAPK3/Akt pathways. IL-22R alpha 1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL-22R alpha 1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P78309

	IFNAR1 Protein, Mouse (HEK293, His-Avi) AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1	Mouse	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Mouse (HEK293, Fc) is a recombinant mouse IFNAR1 (E27-T429) with C-terminal His and Avi tags, which is produced in HEK293 cells.

HY-P78457

	IFNAR1 Protein, Human (HEK293, His-Avi) AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1	Human	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Human (HEK293, His-Avi) is a recombinant human IFNAR1 (K28-K436) with C-terminal His and Avi tag, which is produced in HEK293 cells.

HY-P700744

	IL-22R alpha 1 Protein, Cynomolgus (HEK293, His) IL-22R-alpha-1; IL-22RA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11	Cynomolgus	HEK293
	IL-22R α 1 and IL-10R β together form IL20, IL22 and IL24 receptor complexes, activating different signaling pathways. Within the IL22 receptor, IL-22R α 1 binds to IL10RB and mediates IL22 signaling through the JAK/STAT and MAPK1/MAPK3/Akt pathways. IL-22R alpha 1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-22R alpha 1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P703975

	IL-22R alpha 1 Protein, Human (HEK293, His) IL-22R-alpha-1; IL-22RA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11	Human	HEK293

HY-P78141

	IFNAR1 Protein, Human (Biotinylated, HEK293, His-Avi) AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1	Human	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IFNAR1 (K28-K436) with C-terminal His and Avi tag, which is produced in HEK293 cells.

HY-P703993

	IFNAR1 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1	Cynomolgus	HEK293

HY-P70483

	IFNAR1 Protein, Human (HEK293, His) Interferon Alpha/Beta Receptor 1; IFN-R-1; IFN-Alpha/Beta Receptor 1; Cytokine Receptor Class-II Member 1; Cytokine Receptor Family 2 Member 1; CRF2-1; Type I Interferon Receptor 1; IFNAR1; IFNAR	Human	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Human (HEK293, His) is a recombinant human IFNAR1 (K28-K436) with C-terminal 6*His tag, which is produced in HEK293 cells.

HY-P70952

	IFNAR1 Protein, Cynomolgus (HEK293, His) alpha-type antiviral protein; AVP; beta-type antiviral protein; CRF2-1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC; IFN-alpha/beta R1; IFN-alpha/beta receptor 1; IFN-alpha-REC; I	Cynomolgus	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Cynomolgus (HEK293, His) is a recombinant Cynomolgus IFNAR1 (A25-K437) with C-terminal 6*His tag, which is produced in HEK293 cells.

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HY-P83367

	Interferon alpha/beta Receptor 1 Antibody (YA3112) IFNAR1; IFNAR; Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1	WB, IP	Human
	Interferon alpha/beta Receptor 1 Antibody (YA3112) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3112), targeting Interferon alpha/beta Receptor 1, with a predicted molecular weight of 64 kDa (observed band size: 110-130 kDa). Interferon alpha/beta Receptor 1 Antibody (YA3112) can be used for WB, IP experiment in human background.

HY-P84509

	IL10RB Antibody (YA4206) CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2	WB, FC, ELISA	Human, Rat

HY-P84510

	IL10RB Antibody (YA4207) CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2	ICC/IF, FC, ELISA	Human

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