CD25

By Targets:	ADC Antibody (1) Antibody-Drug Conjugates (ADCs) (1) Fluorescent Dye (1) Influenza Virus (1) Interleukin Related (8) MAP4K (1) NO Synthase (1) TGF-β Receptor (1) Transmembrane Glycoprotein (1) Tyrosinase (2)
By Research Areas:	Cancer (6) Inflammation/Immunology (10)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990281

*Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3)*	Interleukin Related	Others
Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) is a rat-derived IgG1, λ type antibody inhibitor, targeting to mouse CD25/IL-2Rα.

HY-108738

Daclizumab Zenapax; Ro 24-7375	Interleukin Related	Inflammation/Immunology Cancer
Daclizumab (Zenapax) is a humanized, monoclonal antibody that blocks *CD25* (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab (Zenapax) reversibly binds to CD25and prevents the interaction of IL-2 with the IL-2R-HA. Daclizumab (Zenapax) can be used for multiple sclerosis research .

HY-155978A

RDN2150 TFA	Tyrosinase	Inflammation/Immunology
RDN2150 (Compound 25) TFA is a ZAP-70 inhibitor (IC₅₀: 14.6 nM). RDN2150 TFA covalently binds to the C346 residue of ZAP-70. RDN2150 TFA inhibits the expression of CD25 and CD69, and inhibits CD4 ⁺ T cell activation. RDN2150 TFA can be used for research of psoriasis .

HY-P99233

Camidanlumab HuMax-TAC	ADC Antibody Transmembrane Glycoprotein Interleukin Related	Cancer
Camidanlumab (HuMax-TAC) is a humanized IgG1 monoclonal antibody against *CD25*. Camidanlumab can be used to synthesize the ADC molecule Camidanlumab tesirine (HY-141599). Camidanlumab can be used in the research of tumors such as lymphoma and leukemia. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-W181026

KLF10-IN-1	Fluorescent Dye	Inflammation/Immunology
KLF10-IN-1 (#48-15) is a KLF10 inhibitor with an IC₅₀ value of 40 μM for KLF10 reporter gene. KLF10-IN-1 can inhibit KLF10-DNA binding and transcriptional activity, block the conversion of CD4+CD25 T cells to CD4+CD25+T regulatory cells, and inhibit the expression of KLF10 target genes. KLF10-IN-1 can be used as a useful mechanistic probe to study KLF10-mediated effects and T regulatory cell biology .

HY-P991110

*Anti-Mouse CD25* Antibody (7D4)**	Interleukin Related	Inflammation/Immunology
Anti-Mouse CD25 Antibody (7D4) is a mouse IgG2 monoclonal antibody that targets *CD25*. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-141599

Camidanlumab tesirine ADCT 301	Antibody-Drug Conjugates (ADCs) Interleukin Related	Cancer
Camidanlumab tesirine (ADCT 301) is an ADC comprising HuMax-TAC, a human IgG1 mAb directed against human CD25, stochastically conjugated through a dipeptide cleavable linker to a pyrrolobenzodiazepine (PBD) dimer warhead. Camidanlumab tesirine has a drug–antibody ratio (DAR) of 2.3. Camidanlumab tesirine binds human CD25 with picomolar affinity. Camidanlumab tesirine has highly potent and selective cytotoxicity against a panel of CD25-expressing human lymphoma cell lines .

HY-155978

RDN2150	Tyrosinase	Inflammation/Immunology
RDN2150 (Compound 25) is a ZAP-70 inhibitor (IC₅₀: 14.6 nM). RDN2150 covalently binds to the C346 residue of ZAP-70. RDN2150 inhibits the expression of CD25 and CD69, and inhibits CD4 ⁺ T cell activation. RDN2150 can be used for research of psoriasis .

HY-P990736

Efercoleukin alfa	Interleukin Related	Inflammation/Immunology
Efavaleukin alfa is a recombinant fusion protein comprising an IL-2 fused to a human IgG1 Fc. Efavaleukin alfa binds the high-affinity IL-2 receptor alpha chain (CD25) .

HY-P990086

Vopikitug RG-6292; RO-7296682	Interleukin Related	Cancer
Vopikitug is an IgG1-kappa, anti-IL2RA (interleukin 2 receptor alpha subunit, IL-2RA, TAC, p55, CD25) homo sapiens monoclonal antibody. Vopikitug shows antineoplastic activity .

HY-159123

KHK-6	MAP4K	Cancer
KHK-6 is an inhibitor for serine/threonine kinase hematopoietic progenitor kinase 1 (HPK 1) with an IC₅₀ of 20 nM. KHK-6 enhances CD3/CD28-induced cytokine production, enhances CD69, CD25 and HLA-DR markers on CD4+ and CD8+ T cells, and enhances T cell-mediated killing activity of SKOV3 and A549 cells .

HY-P991270

MT204	Interleukin Related	Inflammation/Immunology
MT204 is a humanized IgG1 antibody inhibitor targeting IL-2 of human and rhesus monkey origin. MT204 prevents soluble IL-2 from binding to intermediate-affinity IL-2 receptors and blocks CD25-bound IL-2 on high-affinity IL-2 receptors. MT204 has potently anti-proliferative activity with NKL cells and primary NK cells. MT204 has good tolerability and potent immunosuppressive activity in allogeneic skin graft model of rhesus monkey, promising for immunosuppressive and anti-proliferative therapy .

HY-161255

3,4-DAA	NO Synthase	Inflammation/Immunology
3,4-DAA is an orally active Anthranilic acid derivative with potent immunosuppressive activities. 3, 4-DAA can alleviate the severity of colitis through inhibiting Th1 cells response, promoting Th2 cytokines expression and inducing CD4 ⁺CD25 ⁺ T cells expression . 3,4-DAA suppressed expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) release from EOC20 cells induced by IFN-γ and Lipopolysaccharide .

HY-P2520

Influenza HA (110-119)	Influenza Virus	Inflammation/Immunology
Influenza HA (110-119) is the 110-119 fragment of influenza virus hemagglutinin that can stimulate Treg cells proliferation .

HY-W107024

BMS-986260	TGF-β Receptor	Inflammation/Immunology Cancer
BMS-986260, an immuno-oncology agent, is a potent, selective, and orally active TGFβR1 inhibitor (IC₅₀=1.6 nM). BMS-986260 displays exquisite selectivity for TGFβR1 over its isozyme TGFβR2, as well as in a panel of more than 200 kinases examined. BMS-986260 inhibits TGFβ mediated nuclear translocation of pSMAD2/3 in MINK and NHLF cells lines with an IC₅₀ of 350 nM and 190 nM, respectively .

Cat. No.	Product Name	Target	Research Area

HY-P2520

Influenza HA (110-119)	Influenza Virus	Inflammation/Immunology
Influenza HA (110-119) is the 110-119 fragment of influenza virus hemagglutinin that can stimulate Treg cells proliferation .

Cat. No.	Product Name	Target	Research Area

HY-P990281

*Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3)*	Interleukin Related	Others
Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) is a rat-derived IgG1, λ type antibody inhibitor, targeting to mouse CD25/IL-2Rα.

HY-108738

Daclizumab Zenapax; Ro 24-7375	Interleukin Related	Inflammation/Immunology Cancer
Daclizumab (Zenapax) is a humanized, monoclonal antibody that blocks *CD25* (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab (Zenapax) reversibly binds to CD25and prevents the interaction of IL-2 with the IL-2R-HA. Daclizumab (Zenapax) can be used for multiple sclerosis research .

HY-P99233

Camidanlumab HuMax-TAC	ADC Antibody Transmembrane Glycoprotein Interleukin Related	Cancer
Camidanlumab (HuMax-TAC) is a humanized IgG1 monoclonal antibody against *CD25*. Camidanlumab can be used to synthesize the ADC molecule Camidanlumab tesirine (HY-141599). Camidanlumab can be used in the research of tumors such as lymphoma and leukemia. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P991110

*Anti-Mouse CD25* Antibody (7D4)**	Interleukin Related	Inflammation/Immunology
Anti-Mouse CD25 Antibody (7D4) is a mouse IgG2 monoclonal antibody that targets *CD25*. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990866

*Anti-CD25/IL-2Rα Antibody (7G7B6)*	Inhibitory Antibodies	Others
Anti-CD25/IL-2Rα Antibody (7G7B6) is a kind of mouse IgG2a chimeric antibody, targeting to human CD25/IL-2Rα. The recommend isotype control of Anti-CD25/IL-2Rα Antibody (7G7B6): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-141599

Camidanlumab tesirine ADCT 301	Antibody-Drug Conjugates (ADCs) Interleukin Related	Cancer
Camidanlumab tesirine (ADCT 301) is an ADC comprising HuMax-TAC, a human IgG1 mAb directed against human CD25, stochastically conjugated through a dipeptide cleavable linker to a pyrrolobenzodiazepine (PBD) dimer warhead. Camidanlumab tesirine has a drug–antibody ratio (DAR) of 2.3. Camidanlumab tesirine binds human CD25 with picomolar affinity. Camidanlumab tesirine has highly potent and selective cytotoxicity against a panel of CD25-expressing human lymphoma cell lines .

HY-P990736

Efercoleukin alfa	Interleukin Related	Inflammation/Immunology
Efavaleukin alfa is a recombinant fusion protein comprising an IL-2 fused to a human IgG1 Fc. Efavaleukin alfa binds the high-affinity IL-2 receptor alpha chain (CD25) .

HY-P990086

Vopikitug RG-6292; RO-7296682	Interleukin Related	Cancer
Vopikitug is an IgG1-kappa, anti-IL2RA (interleukin 2 receptor alpha subunit, IL-2RA, TAC, p55, CD25) homo sapiens monoclonal antibody. Vopikitug shows antineoplastic activity .

HY-P991270

MT204	Interleukin Related	Inflammation/Immunology
MT204 is a humanized IgG1 antibody inhibitor targeting IL-2 of human and rhesus monkey origin. MT204 prevents soluble IL-2 from binding to intermediate-affinity IL-2 receptors and blocks CD25-bound IL-2 on high-affinity IL-2 receptors. MT204 has potently anti-proliferative activity with NKL cells and primary NK cells. MT204 has good tolerability and potent immunosuppressive activity in allogeneic skin graft model of rhesus monkey, promising for immunosuppressive and anti-proliferative therapy .

Species:	Human (5) Rhesus Macaque (1) Mouse (2) Rat (1) Cynomolgus (4)
Tag:	His (9) Tag Free (1) Avi (4) Fc (3)
Source:	HEK293 (12) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P7215

	*IL-2R alpha/CD25* Protein, Human (HEK293, N-His)** rHuIL-2Rα, His; TAC-antigen; CD25	Human	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (HEK293, N-His) is a recombinant human IL-2R alpha protein with a His tag at the N-terminus and is expressed in HEK293 cells. It consists of 192 amino acids (E22-C213).

HY-P72550

	*IL-2R alpha/CD25* Protein, Mouse (HEK293, His)** Interleukin-2 receptor subunit alpha; IL-2-RA; CD25; TCGFR; p55	Mouse	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions.IL-2R alpha/CD25 Protein, Mouse (HEK293, His) is a recombinant mouse IL-2R alpha protein with a His tag at the C-terminus and is expressed in HEK293 cells.

HY-P74811

	*IL-2R alpha/CD25* Protein, Mouse (HEK293, hFc)** CD25; IDDM10; IL-2 R alpha; IL2-RA; Interleukin 2 receptor, alpha; TCGFR	Mouse	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Mouse (HEK293, hFc) is a recombinant mouse IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells.

HY-P70628

	*IL-2R alpha/CD25* Protein, Human (HEK293, C-His)** IL-2R alpha; IL-2RA; Interleukin-2 receptor subunit alpha; CD25; p55; TAC antigen; IL2-RA; IL-2R subunit alpha; IL-2-RA; IL-2 receptor subunit alpha	Human	HEK293
	IL-2R alpha protein is the receptor for interleukin 2 and plays a crucial role in immune tolerance by regulating the activity of regulatory T cells (TREG). These TREGs are responsible for inhibiting the activation and expansion of autoreactive T cells.IL-2R alpha/CD25 Protein, Human (HEK293, C-His) is the recombinant human-derived IL-2R alpha protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76785

	*IL-2R alpha/CD25* Protein, Cynomolgus (HEK293)** CD25; IDDM10; IL-2 R alpha; IL2-RA; Interleukin 2 receptor, alpha; TCGFR	Cynomolgus	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Cynomolgus (HEK293) is a recombinant cynomolgus IL-2R alpha protein and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213).

HY-P74809

	*IL-2R alpha/CD25* Protein, Rat (sf9, His)** CD25; IDDM10; IL-2 R alpha; IL2-RA; Interleukin 2 receptor, alpha; TCGFR	Rat	Sf9 insect cells
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Rat (sf9, His) is a recombinant rat IL-2R alpha protein with a His tag at the C-terminus and is expressed in Sf9 insect cells.

HY-P76786

	*IL-2R alpha/CD25* Protein, Cynomolgus (HEK293, Fc)** CD25; IDDM10; IL-2 R alpha; IL2-RA; Interleukin 2 receptor, alpha; TCGFR	Cynomolgus	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Cynomolgus (HEK293, Fc) is a recombinant cynomolgus IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213).

HY-P76787

	*IL-2R alpha/CD25* Protein, Cynomolgus (HEK293, His)** CD25; IDDM10; IL-2 R alpha; IL2-RA; Interleukin 2 receptor, alpha; TCGFR	Cynomolgus	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus IL-2R alpha protein with a His tag at the C-terminus and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213).

HY-P75629

	*IL-2R alpha/CD25* Protein, Rhesus Macaque (Biotinylated, HEK293, His-Avi)** CD25; IDDM10; IL-2 R alpha; IL2-RA; Interleukin 2 receptor, alpha; TCGFR	Rhesus Macaque	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Rhesus Macaque (Biotinylated, HEK293, His-Avi) is a recombinant rhesus macaque IL-2R alpha protein with a His tag and an Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213) and is biotinylated.

HY-P78412

	*IL-2R alpha/CD25* Protein, Human (HEK293, His-Avi)** CD25; IDDM10; IL-2 R alpha; IL2R; IL2RA; p55; TCGFR	Human	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (HEK293, His-Avi) is a recombinant human IL-2R alpha protein with a His tag and an Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 192 amino acids (E22-C213).

HY-P78092

	*IL-2R alpha/CD25* Protein, Human (Biotinylated, HEK293, His-Avi)** CD25; IDDM10; IL-2 R alpha; IL2R; IL2RA; p55; TCGFR	Human	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IL-2R alpha protein with a His tag and an Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 192 amino acids (E22-C213).

HY-P703846

	*IL-2R alpha/CD25* Protein, Cynomolgus (Biotinylated, HEK293, His, Avi)** CD25; IDDM10; IL-2 R alpha; IL2-RA; Interleukin 2 receptor, alpha; TCGFR	Cynomolgus	HEK293

HY-P7374

	*IL-2R alpha/CD25* Protein, Human (HEK293, Fc)** rHuIL-2R α/CD25, Fc Chimera; TAC antigen; IL-2-RA; IL-2 R alpha; IL-2Rα; IL2RA	Human	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (HEK293, Fc) is a recombinant human IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 192 amino acids (E22-C213).

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HY-P83909

	IL2RA Antibody (YA3606) CD25; IL2R; TCGFR; IDDM10	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Monkey, Rat

HY-P81712

	IL-2RA Antibody (YA1457) IL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25	FC, ELISA	Human
	IL-2RA Antibody (YA1457) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1457), targeting IL-2RA. IL-2RA Antibody (YA1457) can be used for FC, ELISA experiment in human background.

HY-P82616

	IL-2 Receptor alpha Antibody (YA2361) IL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25	IHC-P, ICC/IF	Human
	IL-2 Receptor alpha Antibody (YA2361) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2361), targeting IL-2 Receptor alpha. IL-2 Receptor alpha Antibody (YA2361) can be used for IHC-P, ICC/IF experiment in human background.

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