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BCN

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-135973

    ADC Linker Cancer
    BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-SS-NHS
  • HY-133439

    PROTAC Linkers ADC Linker Cancer
    BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG4-NHS ester
  • HY-156317

    ADC Linker Cancer
    BCN-endo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    BCN-endo-PEG7-maleimide
  • HY-W096079

    ADC Linker Cancer
    BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    BCN-endo-PEG4-NHS
  • HY-173390

    Drug Intermediate Biochemical Assay Reagents Others
    BCN-E-BCN is a strained cycloalkyne-based probe designed for detecting protein sulfenylation, the primary intermediate in protein oxidation. This structurally constrained cycloalkyne compound specifically recognizes sulfenic acid groups formed during thiol oxidation, while remaining completely unreactive toward other oxidative states (such as free thiols, sulfinic, or sulfonic acid groups). Researchers can leverage its efficient conjugation with azide-bearing tags through copper-free click chemistry to amplify detection signals. Compared to conventional detection methods, BCN-E-BCN demonstrates superior reaction kinetics and enhanced sensitivity. With these advantages, BCN-E-BCN shows great promise as an effective tool for protein oxidation research .
    BCN-E-BCN
  • HY-133009

    PROTAC Linkers Cancer
    BCN-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. BCN-PEG4-acid contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG4-acid
  • HY-133437

    PROTAC Linkers Cancer
    BCN-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-alkyne is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG4-alkyne
  • HY-156323

    ADC Linker Cancer
    BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    BCN-exo-PEG4-NHS
  • HY-156324

    ADC Linker Cancer
    BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    BCN-exo-PEG8-NHS
  • HY-136061

    ADC Linker Cancer
    BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-HyNic is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG4-HyNic
  • HY-130925

    ADC Linker Cancer
    BCN-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG4-OH
  • HY-130924

    ADC Linker Cancer
    BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG3-Biotin
  • HY-130926

    ADC Linker Cancer
    BCN-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG3-oxyamine is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG3-oxyamine
  • HY-130927

    ADC Linker Cancer
    BCN-PEG4-Ts is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-Ts is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG4-Ts
  • HY-156322

    ADC Linker Cancer
    BCN-exo-PEG3-maleimide is an ADC Linker containing 3 PEG units. BCN-exo-PEG3-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which enables the further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
    BCN-exo-PEG3-maleimide
  • HY-134734

    ADC Linker Cancer
    BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
    BCN-exo-PEG7-maleimide
  • HY-156320

    ADC Linker Cancer
    BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
    BCN-exo-PEG2-maleimide
  • HY-156311

    ADC Linker Cancer
    BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
    BCN-endo-PEG2-maleimide
  • HY-133438

    PROTAC Linkers Cancer
    BCN-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    BCN-PEG4-hydrazide
  • HY-156319

    ADC Linker Cancer
    BCN-exo-PEG2-NH2 is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-NH2 contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    BCN-exo-PEG2-NH2
  • HY-164590

    Radionuclide-Drug Conjugates (RDCs) Cancer
    BCN-NODAGA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
    BCN-NODAGA
  • HY-164574

    Radionuclide-Drug Conjugates (RDCs) Cancer
    BCN-DOTA is a cyclooctyne-linked DOTA chelator that can be radiolabeled with zirconium-89 as a radionuclide-labeled drug conjugate (RDC) to target specific biomolecules, cells, or tissues.
    BCN-DOTA
  • HY-140152

    ADC Linker Cancer
    BCN-PEG3-VC-PFP ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG3-VC-PFP ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG3-VC-PFP ester
  • HY-156310

    ADC Linker Cancer
    BCN-endo-PEG7-NH2 is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-NH2 contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    BCN-endo-PEG7-NH2
  • HY-133402

    PROTAC Linkers Cancer
    BCN- exo- PEG3- NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN- exo- PEG3- NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-​exo-​PEG3-​NH2
  • HY-130922

    ADC Linker Cancer
    BCN-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG1-Val-Cit-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG1-Val-Cit-OH
  • HY-164577

    Radionuclide-Drug Conjugates (RDCs) Cancer
    BCN-DOTA-GA is a cyclooctyne-linked DOTA chelator that can be labeled with radioactive zirconium-89 and used as a radionuclide-labeled drug conjugate (RDC) to target specific biomolecules, cells or tissues.
    BCN-DOTA-GA
  • HY-130923

    ADC Linker Cancer
    BCN-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG1-Val-Cit-PABC-OH
  • HY-158199

    ADC Linker Cancer
    BCN-HS-PEG2-bis(PNP) (Compound 62) is a p-nitrophenyl-containing ADC linker that can be used to further couple ADC cytotoxins with peptide linkers. BCN-HS-PEG2-bis(PNP) can conjugate with vc-PABC-MMAE (HY-15162) to form Drug-Linker Conjugates for ADC .
    BCN-HS-PEG2-bis(PNP)
  • HY-W111141

    endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne

    Biochemical Assay Reagents Others
    BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is a mitochondrial probe based on the lyophilic bidentate bicyclic ligand BCN and is a control reagent for BCN-TPP. The TPP group is a reactive sulfenic acid probe that targets mitochondria. BCN-TPP is known to affect mitochondrial energy, causing a sharp decrease in basal respiration, causing it to exhibit faster reaction kinetics with sulfonated proteins. BCN-OH does not contain hydrophobic triphenylphosphonium (TPP) ions. Using BCN-OH as a control allows the TPP group to be safely introduced when designing sulfenic acid traps .
    BCN-OH
  • HY-164146

    Drug-Linker Conjugates for ADC Microtubule/Tubulin Cancer
    BCN-HS-PEG2(vcPABC-MMAE)2 is a drug-linker conjugate for ADC consists an ADC linker and a tubulin polymerization inhibitor MMAE (HY-15162). BCN-HS-PEG2(vcPABC-MMAE)2 can be used in the synthesis of antibody-agent conjugates (ADCs) .
    BCN-HS-PEG2(vcPABC-MMAE)2
  • HY-160094

    Ligands for Target Protein for PROTAC Cancer
    BCN-sulfonamide-PEG2-sulfonamide-N-bis ethanol (compound 71) is a Ligands for Target Protein for PROTAC that contains a sulfonamide linker to increase the solubility of the linker-conjugate. BCN-sulfonamide-PEG2-sulfonamide-N-bis ethanol can be used to synthesize PROTACs with antitumor activity .
    BCN-sulfonamide-PEG2-sulfonamide-N-bis(ethanol)
  • HY-148880

    Biochemical Assay Reagents Others
    VHLL-BCN can improve the efficiency of click chemistry reaction. VHLL-BCN can be used for the development of transcription factor (TF)-PROTAC .
    VHLL-BCN
  • HY-145593

    ADC Linker Cancer
    Aminooxy-PEG2-BCN is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Aminooxy-PEG2-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Aminooxy-PEG2-BCN
  • HY-136044

    ADC Linker Cancer
    APN-PEG4-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    APN-PEG4-BCN
  • HY-W096149

    Biochemical Assay Reagents Others
    exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    exo-BCN-NHS carbonate
  • HY-W035129

    Biochemical Assay Reagents Others
    endo-BCN-NHS carbonate is an elastin-like protein (ELP) modification reagent. endo-BCN-NHS carbonate can react with lysine residues in ELP to make ELP carry BCN groups, and then cross-link ELP through strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. endo-BCN-NHS carbonate promotes hydrogel formation. endo-BCN-NHS carbonate is mainly used in cell encapsulation related research .
    endo-BCN-NHS carbonate
  • HY-157054

    Biochemical Assay Reagents Others
    Endo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. Endo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    endo-BCN-L-Lysine
  • HY-W754588

    PROTAC Linkers Others
    exo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    exo-BCN-L-Lysine
  • HY-136085

    ADC Linker Cancer
    Amino-bis-PEG3-BCN is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Amino-bis-PEG3-BCN
  • HY-W879044

    Endo-BCN-PEG15-NH2

    Biochemical Assay Reagents Others
    Endo-BCN-PEG15-amine (Endo-BCN-PEG15-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
    Endo-BCN-PEG15-amine
  • HY-W879025

    Endo-BCN-PEG8-NH2

    Biochemical Assay Reagents Others
    Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
    Endo-BCN-PEG8-amine
  • HY-W879045

    Endo-BCN-PEG5-NH2

    Biochemical Assay Reagents Others
    Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
    Endo-BCN-PEG5-amine
  • HY-133406

    PROTAC Linkers Cancer
    exo BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . exo BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    exo BCN-O-PNB
  • HY-43581

    PROTAC Linkers Cancer
    endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    endo-BCN-O-PNB
  • HY-140350

    PROTAC Linkers Cancer
    5-endo-BCN-pentanoic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-endo-BCN-pentanoic acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    5-endo-BCN-pentanoic acid
  • HY-130557

    PROTAC Linkers Cancer
    endo-BCN-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. endo-BCN-PEG2-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    endo-BCN-PEG2-acid
  • HY-140065

    PROTAC Linkers Cancer
    endo-BCN-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    endo-BCN-PEG8-acid
  • HY-140066

    PROTAC Linkers Cancer
    endo-BCN-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG12-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    endo-BCN-PEG12-acid
  • HY-157052

    PROTAC Linkers Others
    exo-BCN-Fmoc-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-Fmoc-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    exo-BCN-Fmoc-L-Lysine

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