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Results for "

Anti-inflammatory and antioxidative activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Adrenergic Receptor (1) Akt (4) Amyloid-β (1) Antibiotic (1) AP-1 (2) Apoptosis (12) Autophagy (6) Bacterial (8) Beta-secretase (1) Calcium Channel (1) Cathepsin (1) Cholinesterase (ChE) (1) COX (1) DNA/RNA Synthesis (3) Dopamine Receptor (2) Drug Derivative (1) Endogenous Metabolite (2) ERK (3) Fungal (12) GABA Receptor (2) HCV (2) HIV (2) HSP (2) HSV (1) Influenza Virus (5) Isotope-Labeled Compounds (1) JNK (1) Keap1-Nrf2 (2) MMP (1) NADPH Oxidase (1) NF-κB (6) NO Synthase (3) Parasite (4) Phosphodiesterase (PDE) (1) Phospholipase (1) PPAR (2) Prostaglandin Receptor (1) Reactive Oxygen Species (ROS) (4) Reference Standards (16) RSV (2) SARS-CoV (2) TNF Receptor (1) Virus Protease (2) Xanthine Oxidase (1)
By Research Areas:	Cancer (30) Cardiovascular Disease (3) Infection (21) Inflammation/Immunology (41) Metabolic Disease (4) Neurological Disease (13)

By Targets:

Acetyl-CoA Carboxylase (1)

Adrenergic Receptor (1)

Akt (4)

Amyloid-β (1)

Antibiotic (1)

AP-1 (2)

Apoptosis (12)

Autophagy (6)

Bacterial (8)

Beta-secretase (1)

Calcium Channel (1)

Cathepsin (1)

Cholinesterase (ChE) (1)

COX (1)

DNA/RNA Synthesis (3)

Dopamine Receptor (2)

Drug Derivative (1)

Endogenous Metabolite (2)

ERK (3)

Fungal (12)

GABA Receptor (2)

HCV (2)

HIV (2)

HSP (2)

HSV (1)

Influenza Virus (5)

Isotope-Labeled Compounds (1)

JNK (1)

Keap1-Nrf2 (2)

MMP (1)

NADPH Oxidase (1)

NF-κB (6)

NO Synthase (3)

Parasite (4)

Phosphodiesterase (PDE) (1)

Phospholipase (1)

PPAR (2)

Prostaglandin Receptor (1)

Reactive Oxygen Species (ROS) (4)

Reference Standards (16)

RSV (2)

SARS-CoV (2)

TNF Receptor (1)

Virus Protease (2)

Xanthine Oxidase (1)

By Research Areas:

Cancer (30)

Cardiovascular Disease (3)

Infection (21)

Inflammation/Immunology (41)

Metabolic Disease (4)

Neurological Disease (13)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Fat Mass and Obesity-associated Protein (FTO)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-150156

Anti-inflammatory agent 32	Others	Inflammation/Immunology
Anti-inflammatory agent 32 (compound C3) has anti-oxidative and anti-inflammatory activity. Anti-inflammatory agent 32 can be used for skin care products research and development .

HY-125938

Cycloartenyl ferulate 1 Publications Verification Cycloartenol ferulate; Cycloartenol ferulic acid ester	NADPH Oxidase	Inflammation/Immunology Cancer
Cycloartenyl ferulate (Cycloartenol ferulate) is one of the typical triterpene alcohols and possesses several biological activities including anti-oxidative activity, antiallergic activity, anti-inflammatory and anticancer activities .

HY-N3500

Ganoderic acid D2	Endogenous Metabolite	Inflammation/Immunology Cancer
Ganoderic acid D2 (compound 27) is a triterpenoid isolated from Ganoderma lucidum. Ganoderic acid D2 has anticancer, anti-inflammatory and antioxidative activity .

HY-N0783

Eupatilin 5+ Cited Publications	PPAR Autophagy	Neurological Disease Inflammation/Immunology Cancer
Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van., is a PPARα* agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.*

HY-N0344

Farrerol 4 Publications Verification	Others	Neurological Disease Inflammation/Immunology Cancer
Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .

HY-N3006

Sakuranetin 3 Publications Verification	Fungal	Infection Inflammation/Immunology
Sakuranetin is a cherry flavonoid phytoalexin, shows strong antifungal activity . Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury .

HY-120784

Hexafluoro-diallylhexaflurobisphenol	Drug Derivative	Others
Hexafluoro-diallylhexaflurobisphenol is a Honokiol analogue (HA). Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules .

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2	Isotope-Labeled Compounds	Cancer
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

HY-N7937

γ-Asarone	Others	Inflammation/Immunology
γ-Asarone, a phenylpropene, shows strong correlation with the biological activities (anti-oxidative, anti-inflammatory and neurotrophic effects) .

HY-N3006R

Sakuranetin (Standard)	Fungal	Infection Inflammation/Immunology
Sakuranetin is a cherry flavonoid phytoalexin, shows strong antifungal activity . Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury .

HY-N3017R

Artemitin (Standard)	Antibiotic Reference Standards	Infection Inflammation/Immunology
Artemitin (Standard) is the analytical standard of Artemitin. This product is intended for research and analytical applications. Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity .

HY-121054

Chalcone 1 Publications Verification	Bacterial Parasite	Inflammation/Immunology Cancer
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities .

HY-N0765

Isoliquiritin 1 Publications Verification	Fungal	Infection Neurological Disease Inflammation/Immunology
Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity .

HY-N0452

Hyperoside 5+ Cited Publications Quercetin 3-O-galactoside; Quercetin 3-O-β-D-galactopyranoside	Influenza Virus Fungal NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-N0344R

Farrerol (Standard)	Reference Standards Akt ERK JNK NF-κB	Infection Inflammation/Immunology Cancer
Farrerol (Standard) is the analytical standard of Farrerol. This product is intended for research and analytical applications. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .

HY-70072

D609 5+ Cited Publications	Phospholipase	Infection Inflammation/Immunology Cancer
D609, an antitumoural xanthate, is a specific and competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor with a K_i of 6.4 μM. D609 is an antioxidative protector and has antiviral and anti-inflammatory activity .

HY-N7766

Rubropunctatin	Apoptosis	Inflammation/Immunology Cancer
Rubropunctatin, an orange azaphilone pigment, is isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctatin has anti-inflammatory, immunosuppressive and antioxidative effects, and also exhibits anti-tumor activity .

HY-N0321

Caftaric acid trans-Caftaric acid	Others	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Caftaric acid (trans-Caftaric acid) is a polyphenolic antidiuretic, antioxidant and anti-apoptotic agent that can be hydrolyzed by intestinal microbial esterases. Caftaric acid exerts its antioxidant and potential anti-inflammatory effects mainly through intestinal microbial metabolism. Caftaric acid can reduce renal damage, restore electrolyte balance, renal function indicators and antioxidant enzyme activities in a rat albinism model, and further exert anti-oxidative stress and anti-inflammatory activities .

HY-N0003

Honokiol Maximum Cited Publications 58 Publications Verification NSC 293100	Akt Autophagy HCV ERK	Cancer
Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier .

HY-N0783R

Eupatilin (Standard)	Reference Standards PPAR Autophagy	Neurological Disease Inflammation/Immunology Cancer
Eupatilin (Standard) is the analytical standard of Eupatilin. This product is intended for research and analytical applications. Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van., is a PPARα* agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.*

HY-108966

Kushenol C	Beta-secretase	Inflammation/Immunology
Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC₅₀ of 5.45 µM .

HY-N0526

2"-O-Galloylhyperin 1 Publications Verification	Others	Inflammation/Immunology
2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage .

HY-W015635

Diallyl disulfide 1 Publications Verification	Others	Cancer
Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC₅₀ of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .

HY-121054R

Chalcone (Standard)	Bacterial Parasite	Inflammation/Immunology Cancer
Chalcone (Standard) is the analytical standard of Chalcone. This product is intended for research and analytical applications. Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities .

HY-N0765R

Isoliquiritin (Standard)	Reference Standards Fungal	Infection Neurological Disease Inflammation/Immunology
Isoliquiritin (Standard) is the analytical standard of Isoliquiritin. This product is intended for research and analytical applications. Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity .

HY-N0293

Paeoniflorin 25+ Cited Publications Peoniflorin	HSP	Infection Neurological Disease Cancer
Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .

HY-N0452R

Hyperoside (Standard) Quercetin 3-O-galactoside (Standard); Quercetin 3-O-β-D-galactopyranoside (Standard)	Reference Standards Influenza Virus Fungal NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Hyperoside (Standard) is the analytical standard of Hyperoside. This product is intended for research and analytical applications. Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-17374

Benfotiamine 1 Publications Verification S-Benzoylthiamine O-monophosphate	SARS-CoV HIV	Infection Metabolic Disease Inflammation/Immunology
Benfotiamine (S-Benzoylthiamine O-monophosphate) is a vitamin B1 derivative that exhihibits potent antioxidative and anti-inflammatory activity. Benfotiamine can be used for the research of various secondary diabetic complications. Benfotiamine also can be used in infectious diseases such as HIV and COVID-19 .

HY-N4226

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid	AP-1	Inflammation/Immunology Cancer
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function .

HY-N0003R

Honokiol (Standard) NSC 293100 (Standard)	Reference Standards Akt Autophagy HCV ERK	Cancer
Honokiol (Standard) is the analytical standard of Honokiol. This product is intended for research and analytical applications. Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier .

HY-N0662

Amentoflavone 10+ Cited Publications Didemethyl-ginkgetin	Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N0293R

Paeoniflorin (Standard) Peoniflorin (Standard)	Reference Standards HSP	Infection Neurological Disease Cancer
Paeoniflorin (Standard) is the analytical standard of Paeoniflorin. This product is intended for research and analytical applications. Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .

HY-N2082

Isorhamnetin 3-O-galactoside 1 Publications Verification Cacticin	Others	Cardiovascular Disease Inflammation/Immunology
Isorhamnetin 3-O-galactoside (Cacticin), a flavonoid glycoside isolated from Artemisia capillaris Thunberg, which ameliorates CCl4-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory signaling pathways. Isorhamnetin 3-O-galactoside (Cacticin) has antithrombotic and anti-inflammatory activities .

HY-135981

CMS-121 2 Publications Verification	Acetyl-CoA Carboxylase	Neurological Disease Inflammation/Immunology
CMS-121 is a quinolone derivative and an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage with EC₅₀ values of 7 nM and 200 nM, respectively. CMS-121 has strong neuroprotective, anti-inflammatory, antioxidative and renoprotective activities .

HY-W015635R

Diallyl disulfide (Standard)	Reference Standards Others	Cancer
Diallyl disulfide (Standard) is the analytical standard of Diallyl disulfide. This product is intended for research and analytical applications. Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC₅₀ of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .

HY-N8160

Dehydrocurdione	Keap1-Nrf2 Reactive Oxygen Species (ROS)	Inflammation/Immunology
Dehydrocurdione, a zedoary-derived sesquiterpene, induces heme oxygenase (HO)-1, an antioxidative enzyme, in RAW 264.7 macrophages. Dehydrocurdione interacts with Keap1, resulting in Nrf2 translocation followed by activation of the HO-1 E2 enhancer. Dehydrocurdione suppresses lipopolysaccharide-induced NO release, a marker of inflammation. Anti-inflammatory activity .

HY-N0120

(E/Z)-Polydatin 1 Publications Verification (E/Z)-Piceid	Others	Inflammation/Immunology
(E/Z)-Polydatin ((E/Z)-Piceid) is the E/Z mixture of Polydatin (HY-N0120A). Polydatin is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions .

HY-17374R

Benfotiamine (Standard) S-Benzoylthiamine O-monophosphate (Standard)	Reference Standards HIV SARS-CoV	Infection Metabolic Disease Inflammation/Immunology
Benfotiamine (Standard) is the analytical standard of Benfotiamine. This product is intended for research and analytical applications. Benfotiamine (S-Benzoylthiamine O-monophosphate) is a vitamin B1 derivative that exhihibits potent antioxidative and anti-inflammatory activity. Benfotiamine can be used for the research of various secondary diabetic complications. Benfotiamine also can be used in infectious diseases such as HIV and COVID-19 .

HY-N3237

Mulberrofuran H	Dopamine Receptor	Inflammation/Immunology
Mulberrofuran H is a 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.). Mulberrofuran H demonstrates potent inhibition against substrates L-tyrosine (IC₅₀=4.45 µM) and L-DOPA (IC₅₀=19.70 µM). Mulberrofuran H also shows potent anti-inflammatory and antioxidative activities .

HY-N0526R

2"-O-Galloylhyperin (Standard)	Reference Standards Others	Inflammation/Immunology
2"-O-Galloylhyperin (Standard) is the analytical standard of 2"-O-Galloylhyperin. This product is intended for research and analytical applications. 2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage .

HY-N0662R

Amentoflavone (Standard) Didemethyl-ginkgetin (Standard)	Reference Standards Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N0327

Lobetyolin 4 Publications Verification	Apoptosis Xanthine Oxidase	Metabolic Disease
Lobetyolin, a bioactive compound, is derived from Codonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidase inhibiting activities. Lobetyolin also induces the apoptosis via the inhibition of ASCT2-mediated glutamine metabolism . Lobetyolin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N0540

Cynaroside 5+ Cited Publications Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside	Influenza Virus DNA/RNA Synthesis Apoptosis Parasite Bacterial Fungal	Infection Cardiovascular Disease Cancer
Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

HY-145532

S-Allylmercaptocysteine	Apoptosis NF-κB Keap1-Nrf2	Inflammation/Immunology Cancer
S-allylmercaptocysteine, an organic sulfur compound extracted from garlic, has anti-inflammatory and anti-oxidative effects for various pulmonary diseases. S-allylmercaptocysteine achieves its anti-cancer effect through a variety of pathways such as inducing the apoptosis of cancer cells through the TGF-β signaling pathway, or reducing the NF-κB activity and up-regulating Nrf2 to achieve the effects of anti-inflammation and anti-oxidation .

HY-172977

FGA139	Cathepsin NO Synthase TNF Receptor	Neurological Disease Inflammation/Immunology
FGA139 is a cysteine proteases inhibitor with IC₅₀ values of 4.98/3.14 μM for cathepsin B/L. FGA139 reduces LPS-induced NO production in RAW264.7 cells and tumor necrosis factor (TNFα) levels in microglia, and has anti-oxidative stress and anti-inflammatory activities. FGA139 promotes the secretion of neuroprotective metabolites purine and linoleic acid by LPS-stimulated microglia. FGA139 can be used in neuroinflammatory diseases research .

HY-N4226R

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (Standard)	Reference Standards AP-1	Inflammation/Immunology Cancer
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (Standard) is the analytical standard of 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid. This product is intended for research and analytical applications. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function[1].

HY-N0540R

Cynaroside (Standard) Luteolin 7-glucoside (Standard); Luteolin 7-O-β-D-glucoside (Standard)	Apoptosis DNA/RNA Synthesis Parasite Bacterial Influenza Virus Fungal Reference Standards	Infection Cancer
Cynaroside (Standard) is the analytical standard of Cynaroside. This product is intended for research and analytical applications. Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

HY-N0017

Bergenin 5 Publications Verification Cuscutin	NF-κB Autophagy Apoptosis Bacterial Fungal Virus Protease	Infection Inflammation/Immunology Cancer
Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties .

HY-N3945R

Glaucine (Standard) O,O-Dimethylisoboldine (Standard); S-(+)-Glaucine (Standard); NSC 34396 (Standard)	Reference Standards Phosphodiesterase (PDE) Calcium Channel Adrenergic Receptor Dopamine Receptor Influenza Virus	Infection Inflammation/Immunology
Glaucine (Standard) is the analytical standard of Glaucine. This product is intended for research and analytical applications. Glaucine (O,O-Dimethylisoboldine) is an alkaloid isolated from Glaucium flavum with antitussive, bronchodilation and anti-inflammatory properties. Glaucine is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor with Kis of 3.4 μM in human bronchus and polymorphonuclear leukocytes. Glaucine is also a non-selective α-adrenoceptor antagonist, a Ca2+ entry blocker, and a weak dopamine D1 and D2 receptor antagonist. Glaucine has antioxidative and antiviral activities .

HY-N1401

20(R)-Ginsenoside Rh2 1 Publications Verification	MMP Apoptosis HSV DNA/RNA Synthesis NO Synthase Prostaglandin Receptor Reactive Oxygen Species (ROS) Akt	Infection Inflammation/Immunology Cancer
20(R)-Ginsenoside Rh2 is an orally active protopanaxadiol-type saponin with multiple biological activities. 20(R)-Ginsenoside Rh2 exerts a significant inhibitory effect on non-small cell lung cancer and liver cancer by inducing cell cycle arrest and promoting apoptosis. 20(R)-Ginsenoside Rh2 exerts anti-γ-herpesvirus effects by inhibiting viral DNA replication. 20(R)-Ginsenoside Rh2 inhibits inflammatory mediators by reducing the levels of NO, PGE2, and ROS; it can delay skin photoaging by reducing ROS and inhibiting MMP-9/2 activity. 20(R)-Ginsenoside Rh2 accelerates the recovery after muscle injury by activating the Akt1/PKB signaling pathway. 20(R)-Ginsenoside Rh2 can inhibit osteoclast formation and exert an anti-osteoporosis effect .

Cat. No.	Product Name

HY-L042

Glycoside Compound Library

817 compounds

Glycosides are compounds in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Many biologically active compounds are glycosides. Glycosides comprise several important classes of compounds such as hormones, sweeteners, alkaloids, flavonoids, antibiotics, etc. The glycosidic residue can be crucial for their activity or can only improve pharmacokinetic parameters. Glycosides, which exhibit anti-inflammatory, anti-infection, anti-cancer and anti-oxidative properties, play numerous important roles in living organisms, such as streptomycin, as an aminoglycoside antibiotic, has anti-infection activity. Anthracyclines possess good antibacterial and anti-cancer activities.

MCE Glycoside Compound Library contains a unique collection of 817 glycoside compounds and is a useful tool to discovery glycoside drugs.

HY-L068

Flavonoids Library

529 compounds

Flavonoids are an important class of natural products; particularly, they belong to a class of plant secondary metabolites having a polyphenolic structure, widely found in fruits, vegetables and certain beverages. Flavonoids can be subdivided into different subgroups depending on the carbon of the C ring on which the B ring is attached and the degree of unsaturation and oxidation of the C ring. These subgroups are: flavones, flavonols, flavanones, flavanonols, flavanols or catechins, anthocyanins and chalcones. Flavonoids are now considered as an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications. This is attributed to their anti-oxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties coupled with their capacity to modulate key cellular enzyme function. Naturally occurring flavonoids are known to have biological activities for use as drugs, for example, in diseases like cancer, Alzheimer’s disease (AD), atherosclerosis, etc.

MCE offers a unique collection of 529 natural flavonoid compounds which is a useful tool for drug discovery as an important source of lead compounds.

Cat. No.	Product Name	Category	Target	Chemical Structure