MAOA - monoamine oxidase A Gene

Homo sapiens

Also known as BRNRS; MAO-A

Gene ID: 4128 | Gene type: protein coding

About MAOA

Cytogenetic location: Xp11.3 Genomic coordinates (GRCh38): X:43,655,006-43,746,817 (from NCBI)

This gene has 10 transcripts (splice variants), 147 orthologues, 7 paralogues and is associated with 3 phenotypes. Broad expression in small intestine (RPKM 94.9), fat (RPKM 78.4) and 19 other tissues.

Summary

This gene is one of two neighboring gene family members that encode mitochondrial Enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of Other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

MAOA Products(2)

mRNA	Protein	Name
NM_000240.4	NP_000231.1	amine oxidase [flavin-containing] A isoform 1
NM_001270458.2	NP_001257387.1	amine oxidase [flavin-containing] A isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables monoamine oxidase activity	IDA IDA: Inferred from direct assay	20493079	GOA
enables primary methylamine oxidase activity	IDA IDA: Inferred from direct assay	20493079	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAOA Protein Structure

Amino_oxidase

0
100
200
300
400
527 a.a.

Protein Preferred Names

Protein Names

amine oxidase [flavin-containing] A

monoamine oxidase type A

MAOA Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	MAOA	P21397	MAOB	Homo sapiens	P27338	Crosslink	30021884
Intra	MAOA	P21397	MAOB	Homo sapiens	P27338	Anti Tag CoIP	33961781
Intra	MAOA	P21397	MAOB	Homo sapiens	P27338	Anti Tag CoIP	28514442

Cross: Cross-species interaction Intra: Intraspecies interaction

MAOA Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82291	Monoamine Oxidase A Antibody (YA2036)	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

Related Diseases

Diseases

Alias

Dementia

Dementias	Presenile Dementia
Alzheimer Type Dementia	Alzheimer Sclerosis
Alzheimer Disease Dementia	Alzheimer Dementia
Primary Degenerative Alzheimer Type Dementia	End Stage Alzheimer'S Dementia
Alzheimer'S Type Atypical Dementia	Alzheimer Type Presenile Dementia
Early Onset Alzheimer Dementia	Dementia In Alzheimer Disease Type 2
Dementia In Alzheimer Disease With Early Onset	Early Onset Alzheimer Type Dementia, Uncomplicated
Primary Degenerative Alzheimer Type Dementia, Early Onset	Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated
Alzheimer Disease Dementia With Early Onset	Presenile Sclerosis
Presenile Brain Sclerosis	Presenile Alzheimer Brain Sclerosis
Late Onset Alzheimer Dementia	Dementia In Alzheimer Disease Type 1
Dementia In Alzheimer Disease With Late Onset	Primary Degenerative Alzheimer Type Dementia, Late Onset
Sdat - [Senile Dementia, Alzheimer Type]	Alzheimer Disease Dementia With Late Onset
Late Onset Alzheimer Brain Sclerosis	Senile Alzheimer Brain Disease
Senile Alzheimer Brain Sclerosis	Senile Primary Degenerative Alzheimer Type Dementia
Senile Dementia Of The Alzheimer Type	Arteriosclerotic Dementia
Strategic-Infarct Dementia	Post Stroke Dementia
Vascular Cognitive Impairment	Vascular Dementia
Dementia Of The Lewy Body Type	Dementia With Lewy Bodies
Sdlt - [Senile Dementia Of The Lewy Body Type]	Senile Dementia Of The Lewy Body Type
Alcohol-Related Dementia	Alcoholic Dementia Nos
Alcohol-Induced Dementia	Alcoholic Brain Syndrome
Chronic Alcoholic Brain Syndrome	Alcohol Dementia
Late Onset Alcoholic Psychosis	Residual And Late-Onset Alcohol-Induced Psychotic Disorder
Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder	Late-Onset Psychoactive Substance-Induced Psychotic Disorder
Inhalant Dementia	Volatile Solvents Dementia
Dementia In Paralysis Agitans	Pdd - [Parkinson Disease Dementia]
Dementia Syndrome Of Parkinson Disease	Dementia In Parkinson Disease
Parkinson Related Dementia	Dementia In Huntington Chorea
Hiv - [Human Immunodeficiency Virus] Dementia	Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex
Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex	Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex
Aids Related Dementia	Dementia Due To Niacin Deficiency

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Antisocial Personality Disorder

Dissocial Personality Disorder	Asocial Personality
Psychopath.Personality	Psychopathic Personality
Psychopathic Personality Disorder	Sociopathic Personality

Inhibited Male Orgasm

Male Orgasmic Disorder

Psychosexual Dysfunction With Male Orgasmic Disorder

Anxiety

Anxiety Disorder	Anxiety Disorders
Anxiety State	Anxieties
Anxiety Neurosis

Paraphilia Disorder

Paraphilia

Paraphilias

Conduct Disorder

Borderline Personality Disorder

Phobia, Specific

Specific Phobia	Simple Phobia
Phobia, Simple	Isolated Phobia

Sexual Sadism

Sadism

Separation Anxiety Disorder

Separation Anxiety Disorder Of Childhood

Paranoid Schizophrenia

Chronic Paranoid Schizophrenia	Paranoid Type Schizophrenia
Paranoid Type Schizophrenia Subchronic State	Paraphrenia - Late
Paraphrenic Schizophrenia	Schizophrenia, Paranoid

Migraine With Or Without Aura 1

Migraine	Migraine With Or Without Aura, Susceptibility To, 1
Migraine Disorder	Migraine Variant
Migraines	Migraine Disorders
Mgr1	Mgau
Ma	Migraine With Or Without Aura
Classic Migraine	Common Migraine
Disorder, Migraine	Headache Migraine
Headache Migrainous	Migraine Headache
Migraine Syndrome	Headache Including Migraine
Migraine, Susceptibility To

Impulse Control Disorder

Disruptive, Impulse Control, And Conduct Disorders

Alcoholic Neuropathy

Alcoholic Polyneuropathy	Alcohol-Related Polyneuropathy
Alcohol-Induced Polyneuropathy	Alcoholic Peripheral Neuropathy

Melancholia

Narcissistic Personality Disorder

Heroin Dependence

Serotonin Syndrome

Serotonergic Syndrome	Serotonin Storm
Serotonin Toxicity	Serotonin Toxidrome
Malignant Carcinoid Syndrome

Obsessive-Compulsive Disorder

OCD	Obsessive-Compulsive Disorder, Susceptibility To
Anancastic Neurosis	Obsessive Compulsive Disorder
Anankastic Neurosis	Obsessive-Compulsive Neurosis
Obsessive Compulsive Behavior

Hypochondriasis

Hypochondriacal Disorder	Hypochondria
Hypochondriacal Neurosis	Illness Anxiety Disorder
Health Anxiety Disorder	Hypochondriacal Reaction

Pheochromocytoma

Pheochromocytoma, Susceptibility To	Phaeochromocytoma
Adrenal Gland Chromaffin Paraganglioma	Adrenal Gland Chromaffinoma
Adrenal Gland Paraganglioma	Adrenal Gland Pheochromocytoma
Chromaffin Paraganglioma Of The Adrenal Gland	Intraadrenal Paraganglioma
PCC	Chromaffin Cell Tumor
Medullary Chromaffinoma	Medullary Paraganglioma
Pheochromoblastoma	Pheochromocytomas
Chromaffin Cell Neoplasm	Pheochromocytoma, Malignant

Psychotic Disorder

Psychotic Disorders	Mental Or Behavioural Disorder
Psychotic	Mental Disorders

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Oppositional Defiant Disorder

Disorder	Oppositional Defiance
Behavioural Disorder	Oppositional Defiance
Disruptive Mood Dysregulation Disorder

Pathological Gambling

Compulsive Gambling	Gambling
Gambling, Pathological	Addiction
Betting	Addiction
Gambling	Betting
Pathological	Gambling
Dependence

Brunner Syndrome

Monoamine Oxidase A Deficiency	Antisocial Behavior
BRNRS	Deficiency Of Monoamine Oxidase A
X-Linked Monoamine Oxidase Deficiency	Susceptibility To Antisocial Behavior
Antisocial Behavior, Susceptibility To	Anti-Social Behavior

Barbiturate Abuse

Social Phobia

Phobia, Social	Phobia Social
Phobic Anxiety Disorder

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder	ADHD
Attention Deficit Disorder	Attention Deficit-Hyperactivity Disorder, Susceptibility To
Attention Deficit Disorder With Hyperactivity	Hyperkinetic Disorder
Hyperactivity Of Childhood	Attention-Deficit/Hyperactivity Disorder
Add	Addh
Attention Deficit	Attention Deficit Disorder Of Childhood With Hyperactivity
Attention Deficit Disorder With Hyperactivity Syndrome	Hyperkinetic Syndrome
Attention-Deficit Hyperactivity Disorder	Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type
Disturbance Of Activity And Attention	Disorder Of Activity And Attention
Adhd - [Attention Deficit Hyperactivity Disorder]	Hyperkinetic Disorders
Disorder Of Activity And Attention With Hyperkinesia	Attention Deficit Syndrome With Hyperactivity

Major Depressive Disorder

Seasonal Affective Disorder	Unipolar Depression
Depression	MDD
Depressive Disorder	Unipolar Depression, Susceptibility To
Major Depressive Disorder 1	Major Depressive Disorder, Response To Citalopram Therapy In
Major Depressive Disorder 2	Winter Depression
Single Major Depressive Episode	Sad
Clinical Depression	Major Depression
Depressive Syndrome	Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment
Seasonal Affective Disorder, Susceptibility To	Recurrent Major Depression
Affective Disorder, Seasonal	Depression In A Seasonal Pattern
Depression	Seasonal
Major Depressive Disorder With A Seasonal Pattern	Seasonal Depression
Seasonal Mood Disorder	Mental Depression
Recurrent Major Depressive Episodes

Norrie Disease

Atrophia Bulborum Hereditaria	Episkopi Blindness
Pseudoglioma	ND
Norrie-Warburg Disease	Anderson-Warburg Syndrome
Fetal Iritis Syndrome	Norrie Syndrome
Norrie-Warburg Syndrome	Ndp
Congenital Progressive Oculo-Acoustico-Cerebral Degeneration	Norrie'S Disease
Oligophrenia Microphthalmus	Pseudoglioma Congenita
Whitnall-Norman Syndrome

Narcolepsy

Paroxysmal Sleep	Gelineau Syndrome
Narcoleptic Syndrome	Narcolepsy-Cataplexy Syndrome
Cataplexy And Narcolepsy	Narcolepsy, Without Cataplexy
Gelineau'S Syndrome	Narcolepsy With Or Without Cataplexy
Narcolepsy Nos

Fibromyalgia

Diffuse Myofascial Pain Syndrome	Fibromyalgia Syndrome
Fibromyalgia-Fibromyositis Syndrome	Fibromyositis
Fibrositis	Fms
Myofascial Pain Syndrome	Myofascial Pain Syndromes

Anorexia Nervosa

Anorexia Nervosa, Susceptibility To	ANON
Anorexia Nervosa, Susceptibility To, 1	An
Anorexia Nervosa 1	An - [Anorexia Nervosa]

Trichotillomania

TTM	Hair-Pulling Syndrome
Compulsive Hair Plucking	Hair Pulling Disorder

Agoraphobia

Fear Of Open Spaces

Phobia Of Going Out

Dysthymic Disorder

Dysthymia	Chronic Depressive Disorder
Chronic Depression	Depressive Personality
Depressive Personality Disorder	Persistent Depressive Disorder
Persistent Depression

Huntington Disease

Huntington'S Disease	Huntington Chorea
HD	Huntington'S Chorea
Huntington Chronic Progressive Hereditary Chorea	Juvenile Huntington Disease
Chronic Progressive Chorea	Chronic Progressive Hereditary Chorea
Hc - [Huntington Chorea]	Hereditary Chorea
Progressive Hereditary Chorea

Flying Phobia

Mood Disorder

Mood Disorders

Episodic Mood Disorder

Mental Depression

Depression

Depressive Disorder

Substance Dependence

Panic Disorder

Panic Anxiety Syndrome	Panic
Panic Disorder 1	Episodic Paroxysmal Anxiety Disorder

Personality Disorder

Personality Disorders	Character Disorder
Personality	Specific Personality Disorders
Enduring Personality Change After Psychiatric Illness

Body Mass Index Quantitative Trait Locus 11

OBESITY	Obesity, Susceptibility To
Leanness, Inherited	Obesity, Susceptibility To, Bmiq11
Obesity, Mild, Early-Onset	Obesity, Association With
Obesity, Early-Onset, Susceptibility To	Obesity, Severe
Obesity, Severe, And Type Ii Diabetes	Obesity, Late-Onset
BMIQ11	Obesity Bmiq11
Obesity, Early-Onset	Obesity , Susceptibility To
Simple Obesity Nos	Excess Fat
Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified	Adiposis

Parkinson Disease, Late-Onset

Parkinson Disease	Parkinson'S Disease
PD	PARK
Parkinson Disease, Susceptibility To	Late Onset Parkinson'S Disease
Late Onset Parkinson Disease	Paralysis Agitans
Primary Parkinsonism	Idiopathic Parkinson Disease
Parkinson'S	Parkinson Disease, Late-Onset, Susceptibility To
Parkinson Disease, Age Of Onset, Modifier	Lewy Body Parkinson Disease
Idiopathic Parkinson'S Disease	Pd - [Parkinson Disease]
Parkinson Disease Nos	Parkinson, Nos
Primary Parkinson Disease

Specific Developmental Disorder

Kleptomania

Pathological Stealing

Lesch-Nyhan Syndrome

Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency	LNS
Hprt Deficiency	Complete Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency
Hypoxanthine Guanine Phosphoribosyltransferase Deficiency	X-Linked Hyperuricemia
Choreoathetosis Self-Mutilation Syndrome	Hprt1 Deficiency
Hprt Deficiency, Complete	Deficiency Of Imp Pyrophosphorylase
Hgprt Deficiency	Lesch-Nyhan Disease
Hypoxanthine Guanine Phosphoribosyltransferase 1 Deficiency	Hg-Prt Deficiency
Hypoxanthine-Guanine-Phosphoribosyltransferase Deficiency	Lesch - Nyhan Syndrome
Hprt1 Disorders	Lesch Nyhan Syndrome
Complete Hprt Deficiency Complete	Lesch Nyhan Disease
Complete Hprt Deficiency	Deficiency Of Guanine Phosphoribosyltransferase
Deficiency Of Hypoxanthine Phosphoribosyltransferase	Hypoxanthine Phosphoribosyltransferase Deficiency
Juvenile Gout, Choreoathetosis, Mental Retardation Syndrome	Juvenile Hyperuricemia Syndrome
Lnd	Primary Hyperuricemia Syndrome
Total Hprt Deficiency	Total Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency
X-Linked Primary Hyperuricemia	X-Linked Uric Aciduria Enzyme Defect
Hprt Complete Deficiency	Hprt Deficiency Grade Iv
Hypoxanthine Guanine Phosphoribosyltransferase Complete Deficiency	Hypoxanthine Guanine Phosphoribosyltransferase Deficiency, Grade Iv
Hypoxanthine-Guanine Phosphoribosyltransferase 1 Deficiency	Hprt - [ Hypoxanthine-Guanine Phosphoribosyltransferase] Complete Deficiency
Total Hgprt - [Hypoxanthine-Guanine Phosphoribosyltransferase] Deficiency

Nervous System Disease

Abnormality Of The Nervous System	Nervous System Diseases
Nervous System Disorder

Disease Of Mental Health

Mental Health

Mental Disorders

Sexual Health Disorder

Sexual Health

Chronic Fatigue Syndrome

Myalgic Encephalomyelitis	Postviral Fatigue Syndrome
Cfs	Myalgic Encephalitis
Encephalomyelitis, Myalgic	Chronic Fatigue
Fatigue Syndrome, Chronic	Benign Myalgic Encephalomyelitis
Akureyri	Akureyri Disease
Cfs - [Chronic Fatigue Syndrome]	Epidemic Neuromyasthenia
Myalgic Encephalomyelitis Syndrome	Me - [Myalgic Encephalomyelitis]
Pvfs - [Postviral Fatigue Syndrome]	Neuromyasthenia
Iceland Disease	Icelandic Disease

Pyromania

Firesetting Behavior	Pathological Firesetting
Pathological Fire-Setting

Pure Autonomic Failure

Orthostatic Hypotension	Idiopathic Orthostatic Hypotension
Postural Hypotension	Bradbury-Eggleston Syndrome
Bradbury Eggleston Syndrome	Hypotension, Orthostatic
Hypotension, Postural	Paf
Pure Dysautonomia	Pure Idiopatic Dysautonomia
Hypotension Orthostatic	Primary Orthostatic Hypotension
Chronic Orthostatic Hypotension

Atypical Depressive Disorder

Atypical Depression

Hepatic Encephalopathy

Encephalopathy, Hepatic	Portal-Systemic Encephalopathy
Hepatoencephalopathy	He - [Hepatic Encephalopathy]
Hepatic Encephalopathy Nos	Hepatic Encephalopathy, Stage Unspecified
Hepatic Coma	Hepatocerebral Encephalopathy
Hepatocerebral Intoxication

Severe Pre-Eclampsia

Severe Preeclampsia	Antepartum Severe Pre-Eclampsia
Postpartum Severe Pre-Eclampsia	Severe Pre-Eclampsia, With Delivery
Severe Toxemia	Severe Pre-Eclampsia, Antepartum Condition Or Complication
Severe Pre-Eclampsia, Postpartum Condition Or Complication	Severe Puerperal Pre-Eclampsia
Severe Pre-Eclamptic Toxaemia	Severe Pet - [Pre-Eclamptic Toxaemia]

Phobic Disorder

Phobic Disorders

Phobic Anxiety Disorder

Alzheimer Disease, Familial, 1

Alzheimer Disease	Alzheimer'S Disease
Presenile And Senile Dementia	AD1
Alzheimer Disease, Susceptibility To	Alzheimer Disease, Late-Onset, Susceptibility To
Alzheimer Disease 1, Familial	AD
Familial Alzheimer Disease	Alzheimer Disease, Late-Onset
Alzheimers Dementia	Alzheimer Dementia
Alzheimer Sclerosis	Alzheimer Syndrome
Alzheimer-Type Dementia	Dat
Primary Senile Degenerative Dementia	Sdat
Alzheimer Disease 1	Autosomal Dominant Alzheimer Disease
Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy	Late Onset Alzheimer Disease
Alzheimers Disease	Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy
Late-Onset Alzheimers Disease	Alzheimer'S Disease Pathway Kegg
Dementia Due To Alzheimer'S Disease	Alzheimer Disease Type 1
Alzheimers

Postpartum Depression

Maternity Blues	Postnatal Depression
Depression, Postpartum	Post-Partum Depression
Depression Postpartum

Epilepsy

Epilepsy Syndrome	Epileptic Syndrome
Epilepsies	Symptomatic Epilepsies
Post Traumatic Epilepsy	Traumatic Epilepsy
Traumatic Epileptic	Epilepsy Due To Hippocampal Sclerosis
Epilepsy With Ammon'S Horn Sclerosis	Epilepsy Due To Cortical Dysplasia
Epilepsy Due To Neuronal Migration Disorders

Avoidant Personality Disorder

Anxious Personality Disorder

Personality Disorders

Pick Disease Of Brain

Pick Disease	Pick Disease Of The Brain
Lobar Atrophy Of Brain	Dementia With Lobar Atrophy And Neuronal Cytoplasmic Inclusions
Pick'S Disease	Behavioral Variant Of Frontotemporal Dementia
Dementia In Pick'S Disease	Lobar Atrophy Of The Brain
Bvftd	Bv-Ftd
PIDB	Picks Disease

Post-Traumatic Stress Disorder

PTSD	Traumatic Neurosis
Post Traumatic Stress Disorder	Stress Disorders, Post-Traumatic
Posttraumatic Stress Disorder	Ptsd - [Post Traumatic Stress Disorder]
Trauma-Related Disorders

Bipolar Disorder

Bipolar Depression	Manic Disorder
Depression, Bipolar	Bipolar Disorder Manic Phase
Depressive-Manic Psych.	Manic Bipolar Affective Disorder
Manic Bipolar I Disorder	Manic Depression
Manic Depressive Disorder	Mixed Bipolar Disorder
Bipolar Affective Disorder	Bipolar Affective Psychosis
Bipolar Spectrum Disorder	Manic Depressive Illness
Depression Bipolar	Bipolar Disorder, Mixed
Major Affective Disorder	Major Affective Disorder 1
Major Affective Disorder 2

Voyeurism

Body Dysmorphic Disorder

Dysmorphophobia	Body Dysmorphia
Dysmorphic Syndrome	Body Dysmorphic Disorders

Neurotic Disorder

Neurosis	Reactive Depression
Adjustment Disorders	Neurotic Disorders
Depressive Neurosis	Neurotic Depression
Neurotic Depression Reactive Type	Neurotic Depressive State
Psychoneurosis	Depressive Disorder
Depression, Neurotic

Tobacco Addiction

Nicotine Dependence	Tobacco Addiction, Susceptibility To
Nicotine Addiction	Tobacco Use Disorder
Smoking Habit	Nicotine Dependence, Protection Against
Nicotine Addiction, Protection From	Cigarette Habituation
Cigarette Habituation, Susceptibility To	Smoking Habit, Susceptibility To
Nicotine Dependence, Susceptibility To	Nicotine Addiction, Susceptibility To
Addiction, Tobacco, Susceptibility To	Compulsive Tobacco User Syndrome
Tobacco Dependence	Tobacco Dependence Syndrome
Cigarette Addiction	Cigarette Dependence
Smoking Addiction	Smokers Syndrome

Sudden Infant Death Syndrome

SIDS	Sudden Infant Death Syndrome, Susceptibility To
Cot Death	Crib Death
Sudden Death Of Nonspecific Cause In Infancy	Sudden Infant Death
Death, Sudden, Syndrome, Infant

Generalized Anxiety Disorder

Anxiety Generalized

Short-Rib Thoracic Dysplasia 4 With Or Without Polydactyly

Asphyxiating Thoracic Dystrophy 4	SRTD4
Atd4	Jatd
Jeune Asphyxiating Thoracic Dystrophy	Jeune Syndrome 4

Restless Legs Syndrome

Wed	Willis-Ekbom Disease
Restless Leg Syndrome	Ekbom Syndrome
Wittmaack-Ekbom Syndrome	Willis Ekbom Disease
Ekbom'S Syndrome	Rls
Restless Legs	Restless Legs Syndrome, Susceptibility To

Alcohol Dependence

Alcoholism	Alcohol Dependence, Susceptibility To
Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against	Alcohol Dependence, Protection Against
Alcoholism, Susceptibility To	Alcoholic Intoxication, Chronic
Pharyngeal Neoplasms	Chronic Alcoholism
Dipsomania	Alcohol Addiction
Ethanol Dependence	Chronic Ethanolism
Chronic Alcoholic Disease Nos	Alcoholic Disease Nos
Alcoholic

Non-Syndromic X-Linked Intellectual Disability 20

Mrx20

Fragile X Syndrome

FXS	Martin-Bell Syndrome
Fraxa Syndrome	Marker X Syndrome
X-Linked Mental Retardation And Macroorchidism	Fragile X Mental Retardation Syndrome
Fra Syndrome	Mental Retardation, X-Linked, Associated With Marxq28
Frax Syndrome	Symptomatic Form Of Fragile X Syndrome In Female Carriers
Fragile-X Syndrome	Fraxe Syndrome

Intermittent Explosive Disorder

Explosive Personality Disorder

Tic Disorder

Tics	Behavioral Tic

Exhibitionism

Gilles De La Tourette Syndrome

Tourette Syndrome	Tourette Disorder
GTS	Ts
Gilles De La Tourette'S Syndrome	Motor-Verbal Tic Disorder
Guinon'S Disease	Psychogenic Tics
Tourette'S Syndrome	Chronic Motor And Vocal Tic Disorder
Td	Tourette'S Disease
Combined Vocal And Multiple Motor Tic Disorder [De La Tourette]	Combined Vocal And Multiple Motor Tic Disorder
Tic De La Tourette

Pedophilia

Paedophilia

Drug Dependence

Substance Abuse

Substance-Related Disorders

Substance Abuse Problem

Autism Spectrum Disorder

Asd	Autism Spectrum Disorders
Autistic Continuum	Pervasive Developmental Disorder
Pervasive Development Disorder	Autistic Behavior
Autistic Disorder	Autistic
Autistic Disorder Of Childhood Onset	Infantile Autism
Childhood Autism	Kanner Syndrome
Pervasive Developmental Delay Nos	Pervasive Developmental Disorder, Not Otherwise Specified

Alcohol Use Disorder

Alcohol Abuse	Alcoholism
Ethanol Abuse	Alcohol Addiction
Alcohol Dependence	Alcoholic Intoxication, Chronic
Alcohol-Related Disorders

Dependent Personality Disorder

Endogenous Depression

Clinical Depression	Unipolar Depression
Depressive Disorder

Related Agents

Approval

Bioactive Molecules (28)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-14536	Methylene Blue	Inhibitor	95.05%	Unkown
HY-14197A	Clorgyline hydrochloride	Inhibitor	99.92%	Unkown
HY-N0159	Paeonol		99.98%	Unkown
HY-14280	Entacapone	Inhibitor	99.97%	Yes
HY-14199	Selegiline hydrochloride	Inhibitor	99.94%	Unkown
HY-A0091A	Pargyline	Inhibitor	99.92%	Unkown
HY-A0091	Pargyline hydrochloride	Inhibitor	99.91%	Unkown
HY-B1018A	Phenelzine sulfate	Inhibitor	99.96%	Unkown
HY-70057	Safinamide	Inhibitor	99.86%	Yes
HY-B0534	Moclobemide	Inhibitor	99.12%	Yes
HY-B1359	Methylene blue trihydrate	Inhibitor	98.0%	Yes
HY-14855B	Tedizolid phosphate	Inhibitor	99.65%	Yes
HY-14197	Clorgyline	Inhibitor	99.76%	Unkown
HY-70057A	Safinamide mesylate	Inhibitor	99.07%	Yes
HY-B0678	Metaxalone		99.77%	Unkown
HY-B0884A	Minaprine dihydrochloride	Inhibitor	99.90%	Unkown
HY-D0958	Methylene blue hydrate	Inhibitor	/	Unkown
HY-100679	Pirlindole	Inhibitor	98.90%	Unkown
HY-14196	Toloxatone	Inhibitor	98.11%	Unkown
HY-B1558A	Bifemelane hydrochloride	Inhibitor	99.86%	Unkown
HY-N0159R	Paeonol (Standard)		99.98%	Unkown
HY-14280R	Entacapone (Standard)	Inhibitor	99.24%	Unkown
HY-B0884	Minaprine	Inhibitor	/	Unkown
HY-14895	Fabomotizole		99.96%	Unkown
HY-14198	Selegiline	Inhibitor	/	Unkown
HY-100679A	Pirlindole mesylate	Inhibitor	/	Unkown
HY-B0678R	Metaxalone (Standard)		/	Unkown
HY-14280A	Entacapone sodium salt	Inhibitor	/	Unkown

Clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Phase
HY-N0529	Rosmarinic acid		99.73%	Phase 3
HY-154977	ETAP	Inhibitor	/	Phase 3
HY-13339	Brofaromine	Inhibitor	99.60%	Phase 2
HY-100178	CX-157	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (98)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-W008566	Norharmane	Inhibitor	99.93%	Unkown
HY-B1311	Proadifen hydrochloride		99.95%	Unkown
HY-110130	RN-1 dihydrochloride	Inhibitor	99.13%	Unkown
HY-N0126	Xanthone	Inhibitor	99.97%	Unkown
HY-W015490	1,4-Naphthoquinone	Inhibitor	99.97%	Unkown
HY-N2554	Osthenol		99.27%	Unkown
HY-16677A	Mofegiline hydrochloride	Inhibitor	99.57%	Unkown
HY-E70074	Monoamine oxidase, plasma		/	Unkown
HY-164099	LSD1/HDAC6-IN-2	Inhibitor	99.66%	Unkown
HY-19333	OG-L002	Inhibitor	99.81%	Unkown
HY-124591	TC-2153	Inhibitor	98.73%	Unkown
HY-100588	VU0364770	Agonist	99.94%	Unkown
HY-14536A	Methylene blue (purity≥70%)	Inhibitor	95.0%	Unkown
HY-Y1322	Triphenyl phosphate	Activator	99.67%	Unkown
HY-131036	MAO-IN-M30 dihydrochloride	Inhibitor	99.25%	Unkown
HY-145259	HDAC6-IN-3	Inhibitor	98.0%	Unkown
HY-N12485	MAO-A inhibitor 1	Inhibitor	98.55%	Unkown
HY-14201	Lazabemide	Inhibitor	99.95%	Unkown
HY-156255	MAO-B-IN-25	Inhibitor	99.11%	Unkown
HY-151466	HIF-1α-IN-5	Inhibitor	99.95%	Unkown
HY-D0004	Azure B	Inhibitor	98.13%	Unkown
HY-W010130	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone	Inhibitor	99.96%	Unkown
HY-14260	RS 8359	Inhibitor	97.35%	Unkown
HY-W655727	(-)-2-Phenylpropylamine	Inhibitor	96.14%	Unkown
HY-N2336	Rosmarinic acid racemate	Inhibitor	98.01%	Unkown
HY-100027A	Ro 41-1049 hydrochloride	Inhibitor	99.96%	Unkown
HY-101578	2614W94	Inhibitor	99.76%	Unkown
HY-121072	ASS234	Inhibitor	99.6%	Unkown
HY-125515	Tetrahydroharmine	Inhibitor	98.00%	Unkown
HY-14280S	Entacapone-d10	Inhibitor	98.0%	Unkown
HY-151596	MAO-A/5-HT2AR-IN-1	Inhibitor	99.71%	Unkown
HY-70057S1	Safinamide-d4-1	Inhibitor	98.90%	Unkown
HY-B1018AS	Phenelzine-d5 sulfate	Inhibitor	99.97%	Unkown
HY-N0126R	Xanthone (Standard)	Inhibitor	99.99%	Unkown
HY-W015490S	1,4-Naphthoquinone-d6	Inhibitor	99.20%	Unkown
HY-W275048	MAO-A inhibitor 3	Inhibitor	99.85%	Unkown
HY-100679B	(R)-Pirlindole mesylate	Inhibitor	/	Unkown
HY-108048	Desoxypeganine	Inhibitor	/	Unkown
HY-108048A	Desoxypeganine hydrochloride	Inhibitor	/	Unkown
HY-114915	PSB-1434	Inhibitor	98.05%	Unkown
HY-116097	PSB-1491	Inhibitor	/	Unkown
HY-119885A	(±)-Amiflamine	Inhibitor	99.23%	Unkown
HY-120017	Befloxatone	Inhibitor	/	Unkown
HY-129449	AnnH31	Inhibitor	99.91%	Unkown
HY-134664	8α-(2-Methylacryloyloxy)-hirsutinolide-13-O-acetate	Inhibitor	/	Unkown
HY-135265	Moclobemide N-Oxide	Inhibitor	/	Unkown
HY-14202	Lazabemide hydrochloride	Inhibitor	/	Unkown
HY-143438	2-PAT	Inhibitor	/	Unkown
HY-143721	SSAO inhibitor-2	Inhibitor	/	Unkown
HY-144673	LSD1-IN-12	Inhibitor	/	Unkown
HY-144756	LSD1-IN-15	Inhibitor	/	Unkown
HY-144757	LSD1-IN-16	Inhibitor	/	Unkown
HY-144758	LSD1-IN-17	Inhibitor	/	Unkown
HY-149408	MAOA-IN-1	Inhibitor	/	Unkown
HY-149528	MAO-B-IN-24	Inhibitor	/	Unkown
HY-149978	LSD1-IN-26		/	Unkown
HY-151094	FTEAA	Inhibitor	/	Unkown
HY-151800	MAO-A/B-IN-2	Inhibitor	/	Unkown
HY-152109	AChE/MAO-IN-1	Inhibitor	/	Unkown
HY-152110	AChE/MAO-IN-2	Inhibitor	/	Unkown
HY-15386	Cimoxatone	Inhibitor	/	Unkown
HY-157934	MAO-IN-4	Inhibitor	/	Unkown
HY-157981	AChE-IN-60	Inhibitor	/	Unkown
HY-157982	BChE-IN-28	Inhibitor	/	Unkown
HY-158092	ChEs/MAOs-IN-2	Inhibitor	/	Unkown
HY-158732	MAO-B-IN-33	Inhibitor	/	Unkown
HY-159106	MeSeI		/	Unkown
HY-161240	MAO-B-IN-30	Inhibitor	98.53%	Unkown
HY-162606	MAO-A/B-IN-3	Inhibitor	/	Unkown
HY-162760	COMT-IN-1	Inhibitor	/	Unkown
HY-163322	MAO-A inhibitor 2	Inhibitor	/	Unkown
HY-163618	DHMQ		/	Unkown
HY-170487	MAO-B-IN-38	Inhibitor	/	Unkown
HY-174833	MAO-A-IN-2	Inhibitor	/	Unkown
HY-174834	MAO-B-IN-44	Inhibitor	/	Unkown
HY-176254	LSD1-IN-43	Inhibitor	/	Unkown
HY-176271	MAO-B-IN-45		/	Unkown
HY-178149	MAO-A/B-IN-5	Inhibitor	/	Unkown
HY-B0534S	Moclobemide-d8	Inhibitor	/	Unkown
HY-B0534S1	Moclobemide-d4	Inhibitor	99.0%	Unkown
HY-B0678S	Metaxalone-d3		98.0%	Unkown
HY-B0678S1	Metaxalone-d6		/	Unkown
HY-N12134	Methyl piperate	Inhibitor	/	Unkown
HY-N1638	1-Methyl-2-undecyl-4(1H)-quinolone	Inhibitor	/	Unkown
HY-RS08019	MAOA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08020	Maoa Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08021	Maoa Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-105041	Tedizolid phosphate sodium	Inhibitor	/	Unkown
HY-105127	Brofaromine hydrochloride	Inhibitor	/	Unkown
HY-14198S	Selegiline-d5	Inhibitor	/	Unkown
HY-14199S	Selegiline-d5 hydrochloride	Inhibitor	/	Unkown
HY-19333A	OG-L002 hydrochloride	Inhibitor	/	Unkown
HY-70057S4	Safinamide-d5	Inhibitor	/	Unkown
HY-N13041	Acacetin 7-O-(6-O-malonylglucoside)	Inhibitor	/	Unkown
HY-W029600	6,7-Dimethylisatin	Inhibitor	/	Unkown
HY-W067583	Norharmine	Inhibitor	/	Unkown
HY-W700241	Norharman-d7	Inhibitor	/	Unkown
HY-W792513	WAY-620147	Inhibitor	98.0%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MAOA	VGNC	VGNC:42953
Mus musculus	MAOA	MGD	MGI:96915
Felis catus	MAOA	VGNC	VGNC:68149
Rattus norvegicus	MAOA	RGD	RGD:61898
Bos taurus	MAOA	VGNC	VGNC:31174
Macaca mulatta	MAOA	VGNC	VGNC:74487
Others	MAOA	NCBI