KEAP1 - kelch like ECH associated protein 1 Gene

Sus scrofa

Also known as INRF2

Gene ID: 100136900 | Gene type: protein coding

About KEAP1

Primary_assembly 2: 69,276,336-69,294,382 reverse strand.Sscrofa11.1:CM000813.5

This gene has 4 transcripts (splice variants), 189 orthologues and 54 paralogues. Ubiquitous expression in psoas major muscle (RPKM 3.4), longissimus dorsi muscle (RPKM 29.9) and 8 other tissues.

KEAP1 Products(1)

mRNA	Protein	Name
NM_001114671.1	NP_001108143.1	kelch-like ECH-associated protein 1

KEAP1 Protein Structure

BTB_POZ_KLHL19_KEAP1

PHA03098

Kelch

0
100
200
300
400
500
624 a.a.

Protein Preferred Names

Protein Names

kelch-like ECH-associated protein 1

cytosolic inhibitor of Nrf2

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N0394	L-Cystine		/	Unkown

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-N0005	Curcumin		98.84%	Phase 4
HY-13755	Sulforaphane		99.75%	Phase 4

Pre-clinical Phase

Bioactive Molecules (61)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-100218A	RSL3		99.90%	Unkown
HY-112675	4-Octyl itaconate	Activator	99.98%	Unkown
HY-19543	Brusatol		99.89%	Unkown
HY-101140	KI696	Inhibitor	99.26%	Unkown
HY-110258	ML334	Activator	99.76%	Unkown
HY-134205A	CBR-470-1	Activator	98.03%	Unkown
HY-111126	K67	Activator	98.43%	Unkown
HY-13755A	(R)-Sulforaphane		99.37%	Unkown
HY-145879	Nrf2 activator-2	Activator	98.92%	Unkown
HY-110275	RA839		98.90%	Unkown
HY-120371	CPUY192018	Inhibitor	98.99%	Unkown
HY-W009731	Dibenzoylmethane	Activator	≥98.0%	Unkown
HY-139047	SW157765	Inhibitor	98.67%	Unkown
HY-131592	Tricetin		99.19%	Unkown
HY-101140A	KI696 isomer	Inhibitor	99.32%	Unkown
HY-149508	Nrf2-IN-3	Inhibitor	99.19%	Unkown
HY-P1328	TAT-14	Activator	99.66%	Unkown
HY-122054A	BPK-29 hydrochloride	Inhibitor	98.28%	Unkown
HY-139620A	MS83 epimer 1		/	Unkown
HY-149010	NXPZ-2	Inhibitor	/	Unkown
HY-100218C	(1R,3R)-RSL3		99.52%	Unkown
HY-122054	BPK-29	Inhibitor	≥99.0%	Unkown
HY-110258B	(R,S,R)-ML334		98.57%	Unkown
HY-121523	MIND4-17	Activator	99.93%	Unkown
HY-139620	MS83	Chemical	/	Unkown
HY-150579	Keap1-Nrf2-IN-13	Inhibitor	96.77%	Unkown
HY-124834	Nrf2 activator-10		/	Unkown
HY-124941	7-Deacetylgedunin	Activator	/	Unkown
HY-139862	Keap1-Nrf2-IN-3	Inhibitor	/	Unkown
HY-143892	Keap1-Nrf2-IN-5	Inhibitor	/	Unkown
HY-143893	Keap1-Nrf2-IN-6	Inhibitor	/	Unkown
HY-144099	Keap1-Nrf2-IN-4		/	Unkown
HY-146577	Keap1-Nrf2-IN-7	Inhibitor	/	Unkown
HY-146578	Keap1-Nrf2-IN-8	Inhibitor	/	Unkown
HY-147517	Keap1-Nrf2-IN-9	Inhibitor	/	Unkown
HY-147548	Keap1-Nrf2-IN-10	Inducer	/	Unkown
HY-147924	Keap1-Nrf2-IN-11	Inhibitor	/	Unkown
HY-149245	Keap1-Nrf2-IN-15	Inhibitor	/	Unkown
HY-150578	Keap1-Nrf2-IN-12	Inhibitor	/	Unkown
HY-151362	Keap1-Nrf2-IN-14	Inhibitor	/	Unkown
HY-155997	Anti-inflammatory agent 56	Inhibitor	/	Unkown
HY-156065	S217879	Activator	/	Unkown
HY-157928	Keap1-Nrf2-IN-18	Inhibitor	/	Unkown
HY-157929	Keap1-Nrf2-IN-19	Inhibitor	/	Unkown
HY-158055	Keap1-Nrf2-IN-20	Inhibitor	/	Unkown
HY-160876	BC-1901S	Activator	/	Unkown
HY-161643	S21-1011		/	Unkown
HY-162152	biKEAP1	Inhibitor	/	Unkown
HY-N10313	Dehydrobruceine B		/	Unkown
HY-N8160	Dehydrocurdione		/	Unkown
HY-P10530	Nrf2 (69-84)		/	Unkown
HY-P1328A	TAT-14 TFA	Activator	/	Unkown
HY-P5480	Keap1-Nrf2-IN-16		/	Unkown
HY-P5909	Keap1-Nrf2 probe		/	Unkown
HY-P5909F	FITC-labelled Keap1-Nrf2 probe		/	Unkown
HY-RS07230	KEAP1 Human Pre-designed siRNA Set A		/	Unkown
HY-RS07231	Keap1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS07232	Keap1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-112675S	4-Octyl itaconate-13C5-1		/	Unkown
HY-162096	Keap1-Nrf2-IN-17	Inhibitor	/	Unkown
HY-W505984	TPNA10168	Activator	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	KEAP1	NCBI	NCBI:9817

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