2. Fluorescent Dye
  3. Celluar Organelle Dyes

Celluar Organelle Dyes

Organelles are functional units participating in energy metabolism, protein processing and folding and genetic information regulation. They play a critical role in maintaining homeostasis and in disease development. Organelle-specific fluorescent dyes, designed with precise structural features, can efficiently and accurately label subcellular structures such as mitochondria, endoplasmic reticulum, lysosomes and nucleus, providing reliable and convenient tools for visualizing cellular functions and exploring pathological mechanisms. The fluorescent stock solutions are easy to use with minimized reagent loss, while ensuring experimental reproducibility.

Celluar Organelle Dyes (21):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-DY1022
    BODIPY 581/591 C11 (solution) 217075-36-0
    BODIPY 581/591 C11 (solution) is a BODIPY borofluoroprene derivative with good light stability and low fluorescence artifacts. BODIPY 581/591 C11 can be used for study lipid peroxidation and antioxidant properties in living cells, or detect ferroptosis by reaction with hydroxyl radicals. BODIPY 581/591 C11 is emitted at 591 nm (reduced prototype), or redshifted to 510 nm (oxidized type). The excitation wavelengths were 581 nm (reduced prototype) and 500 nm (oxidized type).
    Solution Concentration: 2 mM
    BODIPY 581/591 C11 (solution)
  • HY-DY1004
    BODIPY 493/503 (solution) 121207-31-6
    BODIPY 493/503 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 493/503 nm.
    Solution Concentration: 5 mM.
    BODIPY 493/503 (solution)
  • HY-DY1005
    Hoechst 33342 trihydrochloride (solution) 875756-97-1
    Hoechst 33342 trihydrochloride (solution) is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
    Solution Concentration: 10 mg/mL
    Hoechst 33342 trihydrochloride (solution)
  • HY-DY1076
    BODIPY TR Cadaverine (solution) 217190-24-4
    BODIPY TR Cadaverine (solution), a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A.
    Solution Concentration: 2 mM
    BODIPY TR Cadaverine (solution)
  • HY-DY1029
    BODIPY-Cholesterol (solution) 878557-19-8
    BODIPY-cholesterol (solution) is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm).
    Solution Concentration: 1 mM
    BODIPY-Cholesterol (solution)
  • HY-DY1042
    TMRM Perchlorate (solution) 115532-50-8
    Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms.
    Solution Concentration: 10 mM
    TMRM Perchlorate (solution)
  • HY-DY1054
    Rhodamine 123 (solution) 62669-70-9
    Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms.
    Solution Concentration: 5 mM
    Rhodamine 123 (solution)
  • HY-DY1057
    TMA-DPH (solution) 115534-33-3
    TMA-DPH (solution) is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm). TMA-DPH is able to anchor on the cell surface and localize to different regions of the phospholipid bilayer. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined.
    Solution Concentration: 10 mM
    TMA-DPH (solution)
  • HY-DY1017
    Filipin complex (solution) 11078-21-0
    Filipin complex (solution)is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm).
    Solution Concentration: 5 mg/mL
    Filipin complex (solution)
  • HY-DY1039
    DiBAC4(3) (solution) 70363-83-6
    DiBAC4(3) (solution) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). DiBAC4(3) can be used to measure cell membrane potential.
    Solution Concentration: 10 mM
    DiBAC4(3) (solution)
  • HY-DY1061
    BODIPY 558/568 C12 (solution) 158757-84-7
    BODIPY 558/568 C12 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 558/568 nm.
    Solution Concentration: 2 mM
    BODIPY 558/568 C12 (solution)
  • HY-DY1023
    TMRE (solution) 115532-52-0
    Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms.
    Solution Concentration: 10 mM
    TMRE (solution)
  • HY-DY1047
    DFHBI-1T (solution) 1539318-36-9
    DFHBI-1T (solution) is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells.
    Solution Concentration: 20 mM
    DFHBI-1T (solution)
  • HY-DY1075
    N-Methylmesoporphyrin IX (solution) 142234-85-3
    N-Methylmesoporphyrin IX (NMM) (solution), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies.
    Solution Concentration: 2 mM
    N-Methylmesoporphyrin IX (solution)
  • HY-DY1040
    LysoTracker Red (solution) 231946-72-8
    LysoTracker Red (solution) is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes.
    Solution Concentration: 1 mM
    LysoTracker Red (solution)
  • HY-DY1073
    MitoPerOx (solution) 1392820-50-6
    MitoPerOx (solution) is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction).
    Solution Concentration: 2 mM
    MitoPerOx (solution)
  • HY-DY1031
    FM4-64 (solution) 162112-35-8
    FM4-64 (solution) is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM4-64 is widely used in endocytic and exospic membrane structure markers.
    Solution Concentration: 5 mM
    FM4-64 (solution)
  • HY-DY1012
    DiL (solution) 41085-99-8
    DiL (solution) is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins.
    Solution Concentration: 5 mM
    DiL (solution)
  • HY-DY1006
    Propidium Iodide (solution) 25535-16-4
    Propidium Iodide (PI) (solution) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
    Solution Concentration: 1 mg/mL
    Propidium Iodide (solution)
  • HY-DY1025
    Laurdan (solution) 74515-25-6
    Laurdan (solution) is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase.
    Solution Concentration: 5 mM
    Laurdan (solution)