2. Biochemical Assay Reagents
  3. Gene Sequencing and Synthesis

Gene Sequencing and Synthesis

Nucleic acids are present in all living organisms and are categorized into two major types: ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). They serves as a carrier of genetic material,with DNA and RNA encode genetic information through nucleic acid sequences, thereby directing protein synthesis. Consequently, nucleic acids are the foundation of biological research.
MCE provides a variety of nucleic acid synthesis raw materials, including modified nucleotide materials, which can be used for nucleic acid biosynthesis, labeling, and gene sequencing.

 

Gene Sequencing and Synthesis (171):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-114364
    UDP-Galactose disodium 137868-52-1 99.42%
    UDP-Galactose disodium is a natural agonist of the P2Y14 receptor with an EC50 of 0.67 μM for the hP2Y14 receptor. UDP-Galactose disodium is a substrate for the transferase beta-1, 4 galactosyltransferase V (B4GALT5). In addition, UDP-Galactose disodium is required for the biosynthesis of several abundant glycoconjugates that form the surface glycocalyx of Leishmania major.
    UDP-Galactose disodium
  • HY-112582C
    N1-Methylpseudouridine-5′-triphosphate trisodium solution (100mM) 99.70%
    N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability.
    N1-Methylpseudouridine-5′-triphosphate trisodium solution (100mM)
  • HY-114365
    UDP-GalNAc disodium 108320-87-2 99.98%
    UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate of EpsC115. EpsC115 is an exopolymeric substances (EPS) N-terminal deletion mutant with the residue 1-115 deletion. UDP-GalNAc UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor.
    UDP-GalNAc disodium
  • HY-156262
    DEPC-Treated Water
    DEPC-Treated Water is ultrapure water that has been sterilized by high temperature and high pressure and does not contain nuclease. It can avoid contamination by non-specific endonucleases and exonucleases and does not affect RNase activity.
    DEPC-Treated Water
  • HY-145974A
    m7GpppAmpG ammonium 99.50%
    m7GpppAmpG ammonium (m7G(5')ppp(5')(2'OMeA)pG ammonium) is a trinucleotide 5′ end cap analog. m7GpppAmpG ammonium binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG ammonium caps RNA with a capping efficiency of 90%. m7GpppAmpG ammonium enhances mRNA stability and translation efficiency. m7GpppAmpG ammonium is used in mRNA therapeutic research.
    m7GpppAmpG ammonium
  • HY-D0882
    Adenosine 5'-diphosphate dicyclohexylammonium 102029-87-8 ≥98.0%
    Adenosine 5'-diphosphate dicyclohexylammonium is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate dicyclohexylammonium induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.
    Adenosine 5'-diphosphate dicyclohexylammonium
  • HY-137697
    ddCTP 66004-77-1
    ddCTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP is a nucleoside analog that targets the reverse transcriptase of HIV. ddCTP can be used for AIDS research.
    ddCTP
  • HY-131787A
    2-Amino-ATP tetrasodium
    2-Amino-ATP tetrasodium is an ATP substitute produced by inserting an amino acid at the C2 position of ATP.
    2-Amino-ATP tetrasodium
  • HY-40293
    N,N-Bis(trifluoromethylsulfonyl)aniline 37595-74-7 99.97%
    N,N-Bis(trifluoromethylsulfonyl)aniline (N-Phenyltrifluoromethanesulfonimide) is a sulfonylation reagent. N,N-Bis(trifluoromethylsulfonyl)aniline can be used for the synthesis of organic compounds.
    N,N-Bis(trifluoromethylsulfonyl)aniline
  • HY-130777A
    AMP-PNP lithium hydrate
    AMP-PNP lithium hydrate is a non-hydrolyzable analog of ATP. AMP-PNP can replace ATP for biological research and is not hydrolyzed by intracellular enzymes. In the study of BtuCD-F, a vitamin B12 transporter, it was found that AMP-PNP can block the channel formed by the two BtuCDs of the BtuCD-F complex, thereby preventing the entry of vitamin B12.
    AMP-PNP lithium hydrate
  • HY-W008661
    Deoxyguanosine triphosphate (trisodium) solution (100mM) 93919-41-6 99.95%
    Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
    Deoxyguanosine triphosphate (trisodium) solution (100mM)
  • HY-W013715A
    Deoxythymidine-5'-triphosphate (trisodium) solution (100mM) 27821-54-1 98.70%
    Deoxythymidine-5'-triphosphate (dTTP) trisodium solution (100mM) is one of the four nucleoside triphosphates used in the synthesis of DNA.
    Deoxythymidine-5'-triphosphate (trisodium) solution (100mM)
  • HY-136648A
    2'-Deoxyadenosine-5'-triphosphate trisodium 54680-12-5 ≥98.0%
    2'-Deoxyadenosine-5'-triphosphate (dATP) trisodium is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate is promising for research of genetic immunodeficiency diseases adenosine deaminase deficiency and purine nucleotide phosphorylase deficiency .
    2'-Deoxyadenosine-5'-triphosphate trisodium
  • HY-141567A
    Pseudouridine 5'-triphosphate trisodium solution (100mM) ≥98.0%
    Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate. Pseudouridine 5'-triphosphate trisodium solution (100 mM) is substituted for UTP to improve the stability and translation efficiency of mRNA and reduce immunogenicity.
    Pseudouridine 5'-triphosphate trisodium solution (100mM)
  • HY-145934A
    UDP-GlcNAz disodium 1611490-64-2 99.74%
    UDP-GlcNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GlcNAc (HY-112174). UDP-GlcNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    UDP-GlcNAz disodium
  • HY-21586B
    7-Methyl-guanosine-5'-triphosphate sodium 99.69%
    7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor.
    7-Methyl-guanosine-5'-triphosphate sodium
  • HY-150145A
    Cy5-UTP sodium (10mM in Water) 99.26%
    Cy5-UTP sodium (10mM in Water) is a cyanine5-labeled UTP analogue that can produce fluorescent probes in vitro transcription reactions with excitation/emission wavelengths of 650/665 nm. Cy5-UTP sodium can be used in FISH, polychromatic fluorescence analysis, especially the two-color expression array combined with Cy5-UTP.
    Cy5-UTP sodium (10mM in Water)
  • HY-101400A
    Deoxycytidine triphosphate (trisodium) solution (100mM) 109909-44-6 99.46%
    Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
    Deoxycytidine triphosphate (trisodium) solution (100mM)
  • HY-117813
    2-Thiouridine 20235-78-3 99.73%
    2-Thiouridine (2-Thioxo-2-deoxouridine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    2-Thiouridine
  • HY-101886
    5-BrUTP sodium salt 161848-60-8 ≥98.0%
    5-BrUTP sodium salt can be used to label RNA to measure the transcription.
    5-BrUTP sodium salt