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Results for "

wound healing activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (7) Antibiotic (1) AP-1 (2) Apoptosis (5) Bacterial (13) Biochemical Assay Reagents (3) Caspase (3) Drug Derivative (1) Endogenous Metabolite (2) FAK (2) Fungal (7) GPR55 (1) HIF/HIF Prolyl-Hydroxylase (2) Influenza Virus (1) Interleukin Related (1) JAK (2) JNK (1) MDM-2/p53 (1) Na+/K+ ATPase (1) NF-κB (2) NO Synthase (1) P2X Receptor (1) p38 MAPK (3) Parasite (1) PARP (1) PD-1/PD-L1 (2) PERK (3) Phosphodiesterase (PDE) (2) PI3K (2) PKA (2) PPAR (2) Prostaglandin Receptor (1) Ras (2) Reactive Oxygen Species (1) Reference Standards (1) Separase (1) STAT (2) Tim3 (2) Toll-like Receptor (TLR) (1) Wnt (2)
By Research Areas:	Cancer (11) Cardiovascular Disease (2) Infection (17) Inflammation/Immunology (14) Metabolic Disease (4) Neurological Disease (8)

By Targets:

Akt (7)

Antibiotic (1)

AP-1 (2)

Apoptosis (5)

Bacterial (13)

Biochemical Assay Reagents (3)

Caspase (3)

Drug Derivative (1)

Endogenous Metabolite (2)

FAK (2)

Fungal (7)

GPR55 (1)

HIF/HIF Prolyl-Hydroxylase (2)

Influenza Virus (1)

Interleukin Related (1)

JAK (2)

JNK (1)

MDM-2/p53 (1)

Na+/K+ ATPase (1)

NF-κB (2)

NO Synthase (1)

P2X Receptor (1)

p38 MAPK (3)

Parasite (1)

PARP (1)

PD-1/PD-L1 (2)

PERK (3)

Phosphodiesterase (PDE) (2)

PI3K (2)

PKA (2)

PPAR (2)

Prostaglandin Receptor (1)

Ras (2)

Reactive Oxygen Species (1)

Reference Standards (1)

Separase (1)

STAT (2)

Tim3 (2)

Toll-like Receptor (TLR) (1)

Wnt (2)

By Research Areas:

Cancer (11)

Cardiovascular Disease (2)

Infection (17)

Inflammation/Immunology (14)

Metabolic Disease (4)

Neurological Disease (8)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W041988

Fmoc-Glu-OMe	Bacterial	Infection
Fmoc-Glu-OMe, a glutamic acid derivative, shows antibacterial activity and gelation property in AgNO₃ solution. Fmoc-Glu-OMe is a mouldable wound healing biomaterial .

HY-N1198

Strictosamide	Parasite Fungal NO Synthase Interleukin Related NF-κB p38 MAPK Na+/K+ ATPase PERK JNK Akt PI3K	Infection Neurological Disease Inflammation/Immunology
Strictosamide is a compound that can be isolated from Nauclea officinalis. Strictosamide has various activities such as anti-inflammatory, analgesic, anti-Plasmodium, antifungal, and promoting wound healing .

HY-19864

Aganepag AGN 210937	Prostaglandin Receptor	Inflammation/Immunology
Aganepag is a potent Prostanoid EP2 receptor agonist, with an EC₅₀ of 0.19 nM, and shows no activity at EP4 receptor. Aganepag can be used in the research of wound healing, scar reduction, scar prevention and wrinkle treatment and prevention.

HY-P1222B

LL-37, human acetate 2 Publications Verification	Bacterial	Infection Inflammation/Immunology
LL-37, human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human acetate could help protect the cornea from infection and modulates wound healing .

HY-P1222

LL-37, human 2 Publications Verification	Bacterial	Infection
LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing .

HY-120435

Tyrothricin	Bacterial Fungal Influenza Virus Antibiotic	Infection
Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin shows activity against bacteria, fungi and some viruses. Tyrothricin containing formulations are used in sore throat agents and in agents for the healing of infected superficial and small-area wounds .

HY-N6580

Ginsenoside Rg4	Bacterial	Infection Metabolic Disease Inflammation/Immunology
Ginsenoside Rg4 is a major protopanaxatriol type ginsenoside isolated from the leaves of Panax ginseng C. A. Meyer. The protopanaxatriol type ginsenosides (such as Ginsenoside Rg4) exhibits various biological activities including anti-septic, anti-diabetic, wound healing, immune-stimulatory, and anti-antioxidant activity .

HY-N3190

Nigracin Poliothyrsoside; Xylosmoside	Others	Others
Nigracin (Poliothyrsoside) is a phenolic glycoside compound with a wound healing activity .

HY-N11901

Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside	Others	Others
Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside can be isolated from the aerial parts of the fern Ophioglossum vulgatum L and has wound healing activity .

HY-N2351

Paeonoside	Others	Infection Metabolic Disease Inflammation/Immunology
Paeonoside is a bioactive compound identified in P. suffruticosa that promotes wound healing and migration in osteoblast differentiation. Paeonoside has also been reported to have some antidiabetic activity and may prevent sepsis-induced lethality .

HY-N2551

Vitamin U chloride S-Methylmethionine sulfonium chloride	Others	Inflammation/Immunology
Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration .

HY-B0764

Bucladesine sodium Maximum Cited Publications 32 Publications Verification Dibutyryl cAMP sodium salt; DBcAMP sodium salt	PKA Phosphodiesterase (PDE)	Inflammation/Immunology
Bucladesine sodium salt (Dibutyryl-cAMP sodium salt) is a stabilized cyclic AMP (cAMP) analog and a selective PKA activator. Bucladesine sodium salt raises the intracellular levels of cAMP. Bucladesine sodium salt is also a phosphodiesterase (PDE) inhibitor. Bucladesine sodium salt has anti-inflammatory activity and can be used for impaired wound healing .

HY-P1222A

LL-37, human TFA 2 Publications Verification	Bacterial	Infection
LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and modulates wound healing .

HY-N6613

Polygalacturonic acid Galacturonic acid polymer	Others	Infection Inflammation/Immunology
Polygalacturonic acid (Galacturonic acid polymer) is transparent colloid, is a major component of the cell wall. Polygalacturonic acid can be used to prepare silver nanoparticles (AgNPs), as an antioxidant and anti-inflammatory that protect cells from destructive effect of elevated ROS and accelerate wound healing. Polygalacturonic acid nanoparticles also displays anti-bacterial activity .

HY-117522

Sepin-1	Separase	Cancer
Sepin-1 is a potent separase inhibitor with an IC₅₀ value of 14.8 µM. Sepin-1 inhibits cell proliferation, migration and wound healing. Sepin-1 decreases the expression of FoxM1 protein and mRNA level. Sepin-1 shows anti-tumor activity .

HY-168873

Anti-MRSA agent 23	Bacterial	Infection
Anti-MRSA agent 23 (compound 11) is a potent anti-methicillin-resistant Staphylococcus aureus agent. Anti-MRSA agent 23 shows antibacterial and antibiofilm activities. Anti-MRSA agent 23 accelerates the reconstruction and healing of MRSA-infected cutaneous wounds by decreasing bacterial loads, attenuating inflammation, and promoting angiogenesis .

HY-B2144I

Chitosan (≥90% deacetylated,viscosity 10 mPa.s) Deacetylated chitin (≥90% deacetylated,viscosity 10 mPa.s); Poly(D-glucosamine) (≥90% deacetylated,viscosity 10 mPa.s)	Biochemical Assay Reagents Bacterial Fungal	Infection Cancer
Chitosan (Deacetylated chitin) (≥90% deacetylated,viscosity 10 mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi. Chitosan (≥90% deacetylated,viscosity 10 mPa.s) can be used as a versatile biomaterial in drug delivery, tissue engineering, and wound healing .

HY-P1884

LL-37, acetylated,amidated	Bacterial	Infection
LL-37, acetylated, amidated is a cathelicidin peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus. The single human cathelicidin peptide LL-37 has antimicrobial and anti-biofilm activity against multiple Gram-positive and Gram-negative human pathogens, and has wound-healing effects on the host .

HY-P0170

TB500 1 Publications Verification	Drug Derivative Akt P2X Receptor	Inflammation/Immunology
TB500 is a synthetic version of an active region of thymosin β₄. TB500 exhibits anti-fibrotic and wound healing activities by inhibiting the Akt signaling pathway and binding to actin. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation .

HY-B2144J

Chitosan (≥90% deacetylated,viscosity 650-700 mPa.s) Deacetylated chitin (≥90% deacetylated,viscosity 650-700 mPa.s); Poly(D-glucosamine) (≥90% deacetylated,viscosity 650-700 mPa.s)	Biochemical Assay Reagents Bacterial Fungal	Infection Cancer
Chitosan (Deacetylated chitin) (≥90% deacetylated, viscosity 650-700 mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi. Chitosan (≥90% deacetylated, viscosity 650-700 mPa.s) can be used as a versatile biomaterial in drug delivery, tissue engineering, and wound healing .

HY-B0764R

Bucladesine (sodium) (Standard)	PKA Phosphodiesterase (PDE)	Inflammation/Immunology
Bucladesine (sodium) (Standard) is the analytical standard of Bucladesine (sodium). This product is intended for research and analytical applications. Bucladesine sodium salt (Dibutyryl-cAMP sodium salt) is a stabilized cyclic AMP (cAMP) analog and a selective PKA activator. Bucladesine sodium salt raises the intracellular levels of cAMP. Bucladesine sodium salt is also a phosphodiesterase (PDE) inhibitor. Bucladesine sodium salt has anti-inflammatory activity and can be used for impaired wound healing .

HY-155286

(7S,8R,17S)-RCTR1	Biochemical Assay Reagents	Infection Inflammation/Immunology
(7S,8R,17S)-RCTR1 is a specialized pro-resolving mediator, that exhibits anti-inflammatory and anti-infective activities. (7S,8R,17S)-RCTR1 promotes pathogen clearance, wound healing, tissue repair and regeneration .

HY-16697

CID 16020046 1 Publications Verification	GPR55	Cancer
CID 16020046 is a potent and selective GPR55 antagonist and inhibits GPR55 constitutive activity with an IC₅₀ of 0.15 μM. CID 16020046 inhibits GPR55-mediated Ca ²⁺ signaling and GPR55-mediated ERK1/2 phosphorylation. CID 16020046 reduces wound healing in endothelial cells and is involved in the regulation of platelet function .

HY-161153

Microtubule inhibitor 9	Apoptosis	Cancer
Microtubule inhibitor 9 (Compound O-7) is a 2-Aryl-1H-benzo [d] imidazole derivative with in vitro anticancer activity. Microtubule inhibitor 9 can induce cell cycle arrest at the G2/M phase and early apoptosis. Microtubule inhibitor 9 inhibits cancer cell migration by inhibiting wound healing and colony formation .

HY-105174

BPC 157	JAK FAK	Inflammation/Immunology
BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .

HY-N0265

Asperosaponin VI 2 Publications Verification	Caspase Apoptosis PERK p38 MAPK Akt HIF/HIF Prolyl-Hydroxylase PPAR	Cardiovascular Disease Neurological Disease
Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .

HY-105174A

BPC 157 acetate	JAK FAK	Neurological Disease Metabolic Disease
BPC 157 acetate is the acetate salt form of BPC 157 (HY-105174). BPC 157 acetate is the 15-amino acide fragment of gastric peptide BPC. BPC 157 acetate exhibits wound healing promoting and neuroprotective activity. BPC 157 acetate maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 acetate ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .

HY-N2907

Atranorin	Wnt Ras Endogenous Metabolite Bacterial Fungal PD-1/PD-L1 Tim3 Akt AP-1 STAT	Infection Neurological Disease Inflammation/Immunology Cancer
Atranorin is a secondary metabolite of lichens and AKT inhibitor. Atranorin possesses multiple activities such as antibacterial, anti-inflammatory, antioxidant, anti-glycation, analgesic, and anti-tumor effects. Atranorin has IC₅₀ values for scavenging DPPH and ABTS free radicals of 117 μM and less than 10 μM, respectively. Additionally, Atranorin also exhibits effects in promoting wound healing. Atranorin can be used in the research of various diseases, including myelodysplastic syndromes, tumors, and inflammatory conditions .

HY-N0265R

Asperosaponin VI (Standard)	Caspase Apoptosis PERK Akt p38 MAPK HIF/HIF Prolyl-Hydroxylase PPAR	Cardiovascular Disease Neurological Disease
Asperosaponin VI (Standard) is the analytical standard of Asperosaponin VI. This product is intended for research and analytical applications. Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .

HY-N2907R

Atranorin (Standard)	Wnt Reference Standards Ras Endogenous Metabolite Bacterial Fungal PD-1/PD-L1 Tim3 Akt AP-1 STAT	Infection Neurological Disease Inflammation/Immunology Cancer
Atranorin (Standard) is the analytical standard of Atranorin (HY-N2907). This product is intended for research and analytical applications. Atranorin is a secondary metabolite of lichens and AKT inhibitor. Atranorin possesses multiple activities such as antibacterial, anti-inflammatory, antioxidant, anti-glycation, analgesic, and anti-tumor effects. Atranorin has IC₅₀ values for scavenging DPPH and ABTS free radicals of 117 μM and less than 10 μM, respectively. Additionally, Atranorin also exhibits effects in promoting wound healing. Atranorin can be used in the research of various diseases, including myelodysplastic syndromes, tumors, and inflammatory conditions .

HY-N0726

Dracorhodin perchlorate Dracohodin perochlorate	Apoptosis Akt PI3K NF-κB MDM-2/p53 Caspase Reactive Oxygen Species Toll-like Receptor (TLR) PARP	Metabolic Disease Cancer
Dracorhodin perchlorate (Dracohodin perochlorate) is a natural product. Dracorhodin perchlorate can be obtained from the natural active molecule Dragon's blood. Dracorhodin perchlorate inhibits PI3K/Akt and NF-κB activation, upregulates p53 expression, activates caspase, produces ROS, and promotes Apoptosis. Dracorhodin perchlorate regulates the TLR4. Dracorhodin perchlorate promotes wound healing, improves diabetes. Dracorhodin perchlorate has anti-tumor activity against prostate cancer, breast cancer, cervical cancer and other cancers .

HY-N6929

Angelic acid	Others	Neurological Disease Cancer
Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .

HY-N0726R

Dracorhodin perchlorate (Standard) Dracohodin perochlorate (Standard)	Apoptosis	Cancer
Dracorhodin perchlorate (Standard) is the analytical standard of Dracorhodin perchlorate. This product is intended for research and analytical applications. Dracorhodin perchlorate (Dracohodin perochlorate) is a natural product. Dracorhodin perchlorate can be obtained from the natural active molecule Dragon's blood. Dracorhodin perchlorate inhibits PI3K/Akt and NF-κB activation, upregulates p53 expression, activates caspase, produces ROS, and promotes Apoptosis. Dracorhodin perchlorate regulates the TLR4. Dracorhodin perchlorate promotes wound healing, improves diabetes. Dracorhodin perchlorate has anti-tumor activity against prostate cancer, breast cancer, cervical cancer and other cancers .

HY-N6929R

Angelic acid (Standard)	Others	Neurological Disease Cancer
Angelic acid (Standard)) is the analytical standard of Angelic acid (HY-N6929). This product is intended for research and analytical applications. Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .

HY-168204

3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid	Bacterial Fungal	Infection
3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid (compound J1) is a potent antimicrobial agent. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid shows anti-gram-positive bacteria and fungi activity. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid can be used as antibiotic adjuvants. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic disrupts the bacterial cell membrane, inserts into the DNA, and binds to DNA gyrase. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic reduces microbial count in a mouse MRSA skin infection model and accelerates wound healing .

Cat. No.	Product Name

HY-L012

Metabolism/Protease Compound Library	5,856 compounds
Metabolism is the set of life-sustaining chemical reactions in organisms. Metabolic pathways are enzyme-mediated biochemical reactions that lead to biosynthesis (anabolism) or breakdown (catabolism) of natural product small molecules within a cell or tissue. Acting as catalysts, enzymes are crucial to metabolism - they allow a reaction to proceed more rapidly - and they also allow the regulation of the rate of a metabolic reaction. Proteases are used throughout an organism for various metabolic processes. Proteases control a great variety of physiological processes that are critical for life, including the immune response, cell cycle, cell death, wound healing, food digestion, and protein and organelle recycling. Imbalances in metabolic activities have been found to be critical in a number of pathologies, such as cardiovascular diseases, inflammation, cancer, and neurodegenerative diseases. MCE designs a unique collection of 5,856 Metabolism/Protease-related small molecules that act as a useful tool for drug discovery of metabolism-related diseases.

Metabolism/Protease Compound Library

5,856 compounds

Metabolism is the set of life-sustaining chemical reactions in organisms. Metabolic pathways are enzyme-mediated biochemical reactions that lead to biosynthesis (anabolism) or breakdown (catabolism) of natural product small molecules within a cell or tissue. Acting as catalysts, enzymes are crucial to metabolism - they allow a reaction to proceed more rapidly - and they also allow the regulation of the rate of a metabolic reaction. Proteases are used throughout an organism for various metabolic processes. Proteases control a great variety of physiological processes that are critical for life, including the immune response, cell cycle, cell death, wound healing, food digestion, and protein and organelle recycling. Imbalances in metabolic activities have been found to be critical in a number of pathologies, such as cardiovascular diseases, inflammation, cancer, and neurodegenerative diseases.

MCE designs a unique collection of 5,856 Metabolism/Protease-related small molecules that act as a useful tool for drug discovery of metabolism-related diseases.

Cat. No.	Product Name	Type