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" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (2) Antibiotic (1) Apoptosis (5) Autophagy (3) Bcl-2 Family (2) Bcr-Abl (3) Biochemical Assay Reagents (1) Calcium Channel (1) CDK (1) Cytochrome P450 (1) E1/E2/E3 Enzyme (2) E3 Ligase Ligand-Linker Conjugates (38) EGFR (1) Epigenetic Reader Domain (21) ERK (1) Estrogen Receptor/ERR (2) FKBP (3) Fluorescent Dye (1) GLP Receptor (1) Glutaminase (1) HDAC (6) HIF/HIF Prolyl-Hydroxylase (2) Histone Methyltransferase (4) Integrin (6) IRAK (1) JAK (1) Ligands for E3 Ligase (21) Ligands for Target Protein for PROTAC (2) MEK (2) Molecular Glues (3) P-selectin (1) p38 MAPK (2) PROTACs (62) Ras (3) RIP kinase (1) SGK (1) STAT (4) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (124) Cardiovascular Disease (10) Infection (1) Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (1)
Click Chemistry:	PROTAC Synthesis (1) Azide (1)
Oligonucleotides:	Aptamers (6)

141

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Fasedienol PH94B	Calcium Channel	Neurological Disease
Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol significantly increases Ca ⁺⁺. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety .

VHL-IN-1	Ligands for E3 Ligase HIF/HIF Prolyl-Hydroxylase	Cancer
VHL-IN-1 (compound 30) is a ubiquitin E3 ligase von Hippel-Lindau (VHL) inhibitor (dissociation constant Kd=37 nM) that stabilizes and induces HIF-1α transcriptional activity. VHL-IN-1 has potential as a HIF-1α stabilizer and degrader of proteolytically targeted chimeras (PROTACs) .

SIM1 1 Publications Verification	PROTACs Epigenetic Reader Domain	Cancer
SIM1 is a potent von Hippel-Lindau (VHL)-based trivalent PROTAC capable of degradation for all BET family members, with preference for BRD2 degradation (IC₅₀=1.1 nM; Kd=186 nM). SIM1 shows sustained anti-cancer activity .

SIAIS178	PROTACs Bcr-Abl	Cancer
SIAIS178 is a potent and selective BCR-ABL degrader based on PROTAC technology with an IC₅₀ of 24 nM. SIAIS178 causes effective degradation of BCR-ABL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. SIAIS178 has anticancer activity .

Caplacizumab ALX-0681; ALX-0081	Integrin Transmembrane Glycoprotein	Cardiovascular Disease
Caplacizumab (ALX-0681) is a humanized anti-von Willebrand factor (vWF) nanobody. Caplacizumab inhibits the binding of vWF with platelet glycoprotein (GP) Ibα. Caplacizumab inhibits the vWF-mediated platelet adhesion and prevents further microthrombi formation. Caplacizumab can be used for the research of thrombotic thrombocytopenic purpura (TTP) .

PROTAC BET degrader-3 1 Publications Verification	PROTACs Epigenetic Reader Domain	Cancer
PROTAC BET Degrader-3 is a PROTAC connected by ligands for von Hippel-Lindau and BET.

*Prepro-von* Willebrand factor (641-650) (bovine)**	Biochemical Assay Reagents	Metabolic Disease
Prepro-von Willebrand factor (641-650) (bovine) is a fragment of Prepro-von Willebrand factor, which binds to type I collagen .

(S,R,S)-AHPC-CO-C9-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-CO-C9-NH2 is a Von Hippel-Lindau (VHL) amino building block that can be used to synthesize E3 ligase ligands required for PROTACs.

GID4 Ligand 3	Ligands for Target Protein for PROTAC	Cancer
GID4 Ligand 3 (compound 16) is a binder of GID4 with an K_d value of 110 μM in vitro and an IC₅₀ value of 148.5 μM. GID4 Ligand 3 can be used for the research related to cereblon and Von Hippel-Lindau .

BT100 sodium	Integrin	Cardiovascular Disease
BT100 (sodium), a aptamer, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .

dTRIM24 5+ Cited Publications	PROTACs Epigenetic Reader Domain	Cancer
dTRIM24 is a selective bifunctional degrader of TRIM24 based on PROTAC, consists of ligands for von Hippel-Lindau and TRIM24.

PROTAC IRAK4 degrader-3	IRAK PROTACs	Inflammation/Immunology
PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau .

MZP-55 1 Publications Verification	Epigenetic Reader Domain PROTACs	Cancer
MZP-55 is a PROTAC connected by ligands for von Hippel-Lindau and BRD3/4, with a K_d of 8 nM for Brd4 ^BD2.

MZP-54 1 Publications Verification	PROTACs Epigenetic Reader Domain	Cancer
MZP-54 is a PROTAC connected by ligands for von Hippel-Lindau and BRD3/4, with a K_d of 4 nM for Brd4 ^BD2.

ZINC13466751	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease Cancer
ZINC13466751 is a potent inhibitor of *HIF-1α/von* Hippel-Lindau interaction with an IC₅₀** of 2.0 µM .

PROTAC BRD4 Degrader-3	PROTACs Epigenetic Reader Domain	Cancer
PROTAC BRD4 Degrader-3 (compound 1004.1) is an efficacious PROTAC connected by ligands for von Hippel-Lindau and BRD4 .

Homo-PROTAC pVHL30 degrader 1 1 Publications Verification	PROTACs	Cancer
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC , consists of two ligands of von Hippel-Lindau.

Egaptivon pegol sodium ARC 1779 sodium	Integrin	Cardiovascular Disease
Egaptivon pegol sodium is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol sodium has anti-thrombotic efficacy.

BT200 sodium	Integrin	Cardiovascular Disease
BT200 sodium, a pegylated form of the aptamer BT100, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .

BT200	Integrin	Cardiovascular Disease
BT200, a pegylated form of the aptamer BT100, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .

VH 101 phenol-alkylC6-amine dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
VH 101 phenol-alkylC6-amine dihydrochloride is a functionalized von-Hippel-Lindau (VHL) protein-ligand that can be used for PROTAC synthesis .

AT6	PROTACs	Cancer
AT6 is a PROTAC AT1 analogue, which is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 with highly selectivity to bromodomain (Brd4).

Egaptivon pegol ARC 1779	Integrin	Cardiovascular Disease
Egaptivon pegol (ARC1779) is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol has anti-thrombotic efficacy.

VHL Ligand 36	Ligands for E3 Ligase	Cancer
VHL Ligand 36 is a von Hippel-Lindau (VHL) ligand. VHL Ligand 36 can be used to synthesize SD-2301 (HY-172946) .

Thalidomide-NH-C10-COOH	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-NH-C10-COOH (compound 6b) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology .

PROTAC Bcl-xL degrader-2	Bcl-2 Family PROTACs	Cancer
PROTAC Bcl-xL degrader-2 is a potent Bcl-xL (Bcl-2 family member) degrader based on von Hippel-Lindau ligand, with an IC₅₀ of 0.6 nM.

GNE7599	Ligands for E3 Ligase	Cancer
GNE7599 is a high-affinity and orally active von Hippel-Lindau (VHL) ligand with a K_d of 540 pM. GNE7599 can be connected to the ligand for protein by a linker to form PROTACs .

(S,R,S)-AHPC-Me hydrochloride VHL ligand 2 hydrochloride; E3 ligase Ligand 1	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein . (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC₅₀ <1 nM .

(S,R,S)-AHPC-Me dihydrochloride VHL ligand 2 dihydrochloride; E3 ligase Ligand 1 dihydrochloride	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC-Me dihydrochloride (VHL ligand 2 dihydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein . (S,R,S)-AHPC-Me dihydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC₅₀ <1 nM .

(S,R,S)-AHPC-Me VHL ligand 2; E3 ligase Ligand 1A	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein . (S,R,S)-AHPC-Me can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC₅₀ <1 nM .

BRD4 degrader AT1 2 Publications Verification	PROTACs Epigenetic Reader Domain	Cancer
BRD4 degrader AT1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 as a highly selective Brd4 degrader, with a K_d of 44 nM for Brd4 ^BD2 in cells.

XY028-133	PROTACs CDK	Cancer
XY028-133 (example 14) is a PROTAC-based CDK4/6 degrader with anti-tumor activity, which consists of ligands for von Hippel-Lindau and CDK .

PROTAC FKBP Degrader-3 1 Publications Verification	PROTACs FKBP	Cancer
PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an von Hippel-Lindau binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader .

UNC6852 2 Publications Verification	Histone Methyltransferase PROTACs	Cancer
UNC6852 is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a von Hippel-Lindau ligand, with an IC₅₀ of 247 nM for EED .

TD-165 1 Publications Verification	PROTACs	Cancer
TD-165 is a PROTAC-based cereblon (CRBN) degrader. TD-165 comprises a?cereblon (CRBN)?ligand binding group, a linker and an?von Hippel-Landau (VHL)?binding group .

(S,R,S)-AHPC-Boc VH032-Boc	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Boc is used in PROTAC technology .

CMP98	PROTACs	Others
CMP98, a PROTAC, is unable to induce degradation of VHL. CMP98 can be used as a negative control compound for CM11 . CMP98 consists of two von Hippel-Lindau ligands on their active domain.

(S,R,S)-AHPC-CO-C9-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-CO-C9-NH2 (hydrochloride) is a von Hippel-Lindau (VHL) amino building block that can be used to synthesize E3 ligase ligands required for PROTACs..

VH 101, acid	Ligands for E3 Ligase	Others
VH 101, acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH 101, acid contains an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand .

(S,R,S)-AHPC monohydrochloride 2 Publications Verification VH032-NH2 monohydrochloride; VHL ligand 1 monohydrochloride	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC (VH032-NH2; VHL ligand 1) hydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein .

LC-2 epimer	PROTACs Ras	Cancer
LC-2 epimer is a differential isomer of LC-2. LC-2 is a mutation-selective PROTAC depressant for KRAS and contains a ligand for the von Hippel Lindau E3 ligase linked to the KRAS inhibitor MRTX849 .

PROTAC BRD4 Degrader-5	PROTACs Epigenetic Reader Domain	Cancer
PROTAC BRD4 Degrader-5 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines .

VH 032 amide-alkylC5-azide	E3 Ligase Ligand-Linker Conjugates	Others
VH 032 amide-alkylC5-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand .

SJFδ	PROTACs p38 MAPK Autophagy	Cancer
SJFδ is a 10-atom linker PROTAC based on von Hippel-Lindau ligand. SJFδ degrades p38δ with a DC₅₀ of 46.17 nM, but does not degrade p38α, p38β, or p38γ .

VH 032 amide-PEG6-amine hydrochloride (S,R,S)-AHPC-PEG6-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
VH 032 amide-PEG6-amine hydrochloride (Step 4) is a functionalized von-Hippel-Lindau protein-ligand (VHL) for PROTAC development, consisting of an E3 ligand and a PEG6 ligand. Terminal amines can be coupled to target protein ligands .

SJF-0661	Ligands for E3 Ligase	Cancer
SJF-0661 is a variant of the von Hippel-Lindau (VHL) protein ligand with no targeted degradation ability and can be used as a control reagent for the VHL ubiquitin ligase ligand. SJF-0661 is a variant obtained by inverting the stereocenter of the key hydroxyproline group in the VHL ligand .

Cat. No.	Product Name

HY-L128

E3 Ligase Ligand Library

88 compounds

Proteolysis-targeting chimera (PROTAC) has been developed to be a useful technology for targeted protein degradation. PROTACs consist of a ligand for E3 ligase (E3 ligase binder), a linker and a ligand (mostly small-molecule inhibitor) for protein of interest（target binder）. Upon binding to the target protein, the PROTACs can recruit E3 for target protein ubiquitination, which is subjected to proteasome-mediated degradation.

Although there are more than 600 E3 ubiquitin ligases, only several with small molecule ligands have been used for designing PROTACs, including Skp1-Cullin-F box complex containing Hrt1 (SCF), Von Hippel-Lindau tumor suppressor (VHL), Cereblon (CRBN), inhibitor of apoptosis proteins (IAPs), and mouse double minute 2 homolog (MDM2).

MCE carefully prepared a unique collection of 88 ligands for E3 ligase, which have been reported to be used in PROTAC design. MCE E3 ligase ligand library is a useful tool for PROTAC development.

HY-L045

Oxygen Sensing Compound Library

3,261 compounds

Oxygen homeostasis regulation is the most fundamental cellular process for adjusting physiological oxygen variations, and its irregularity leads to various human diseases, including cancer. Hypoxia is closely associated with cancer development, and hypoxia/oxygen-sensing signaling plays critical roles in the modulation of cancer progression.

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostasis. A variety of HF-1 target genes have been identified thus far which encode proteins that play key roles in critical developmental and physiological processes including angiogenesis/vascular remodeling, erythropoiesis, glucose transport, glycolysis, iron transport, and cell proliferation/survival.

HIF-1 is a heterodimeric transcription factor consisting of a constitutively expressed β-subunit and an oxygen-regulated α-subunit. The unique feature of HIF-1 is the regulation of HIF-1α expression and activity based upon the cellular O₂ concentration. Under normoxic conditions, hydroxylation of HIF-1α on these different proline residues is essential for HIF proteolytic degradation by promoting interaction with the von Hippel-Lindau tumor-suppressor protein (pVHL) through hydrogen bonding to the hydroxyproline-binding pocket in the pVHL β-domain. As oxygen levels decrease, hydroxylation of HIF decreases; HIF-1α then no longer binds pVHL, and becomes stabilized, allowing more of the protein to translocate to the cell’s nucleus, where it acts as a transcription factor, upregulating (often within minutes) the production of proteins that stimulate blood perfusion in tissues and thus tissue oxygenation.

MCE offers a unique collection of 3,261 oxygen sensing related compounds targeting HIF/HIF Prolyl-Hydroxylase, MAPK/ERK, PI3K/AKT signaling pathways, etc. MCE Oxygen Sensing Compound Library is a useful tool to study hypoxia, oxidative stress and discover new anti-cancer drugs.

Cat. No.	Product Name	Type

HY-D2413

BODIPY FL VH032

BODIPY FL PEG4-VH032

Fluorescent Dyes/Probes

BODIPY FL VH032 is a high-affinity VHL fluorescent probe with a K_d value of 3.01 nM. BODIPY FL VH032 consists of von Hippel-Lindau (VHL) ligand VH032 (HY-120217) and BODIPY FL (HY-43520). BODIPY FL VH032 can be used for time-resolved fluorescence resonance energy transfer (TR-FRET) detection for high-throughput identification and characterization of VHL ligands with maximum excitation emission wavelength: 504/520 nm .

Cat. No.	Product Name	Target	Research Area

HY-P4812

*Prepro-von* Willebrand factor (641-650) (bovine)**	Biochemical Assay Reagents	Metabolic Disease
Prepro-von Willebrand factor (641-650) (bovine) is a fragment of Prepro-von Willebrand factor, which binds to type I collagen .

HY-106428

Icrocaptide ITF1697	P-selectin	Cardiovascular Disease Inflammation/Immunology
Icrocaptide (ITF1697) is a stable Lys-Pro-containing peptide that inhibits the intracellular Ca ²⁺-dependent fusion of Weibel-Palade bodies with the plasma membrane. Icrocaptide exerts its activity at the early stages of endothelial activation and inhibits P-selectin and von Willebrand factor secretion. Icrocaptide can be used for the study of a variety of microvascular disorders .

Cat. No.	Product Name	Target	Research Area

HY-P99227

Caplacizumab ALX-0681; ALX-0081	Integrin Transmembrane Glycoprotein	Cardiovascular Disease
Caplacizumab (ALX-0681) is a humanized anti-von Willebrand factor (vWF) nanobody. Caplacizumab inhibits the binding of vWF with platelet glycoprotein (GP) Ibα. Caplacizumab inhibits the vWF-mediated platelet adhesion and prevents further microthrombi formation. Caplacizumab can be used for the research of thrombotic thrombocytopenic purpura (TTP) .

HY-P99875

Efanesoctocog alfa	Inhibitory Antibodies	Cardiovascular Disease
Efanesoctocog alfa is a B domain-deleted single-chain Factor VIII (FVIII) connected to D'D3 domain of von Willebrand Factor (vWF). Efanesoctocog alfa has an extended half-life. Efanesoctocog alfa can be used for the study of inherited hemophilia A .

Species:	Human (6) Mouse (1)
Tag:	His (4) Tag Free (1) Avi (1) Fc (2)
Source:	HEK293 (3) CHO (1) CHO (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P73541

	Von Willebrand Factor/vWF Protein, Human (CHO, His) von Willebrand factor; vWF; von Willebrand antigen II; F8VWF	Human	CHO
	Von Willebrand Factor/vWF Protein, Human (CHO, His) is the recombinant human-derived Von Willebrand Factor/vWF protein, expressed by CHO, with C-His labeled tag.

HY-P76124

	VHL Protein, Human (His) von Hippel-Lindau disease tumor suppressor; Protein G7; pVHL; VHL	Human	E. coli
	VHL protein is an important component of the von Hippel-Lindau ubiquitination complex and plays a key role in ubiquitination and proteasomal degradation. As a target recruitment subunit in the E3 ubiquitin ligase complex, VHL specifically recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions and regulates cellular responses to oxygen levels. VHL Protein, Human (His) is the recombinant human-derived VHL protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700957

	BPIFA1 Protein, Human BPI fold-containing family A member 1; Lung-specific protein X; PLUNC1; SPLUNC1; von Ebner protein Hl;	Human	E. coli
	BPIFA1 Protein, a lipid-binding protein, exhibits high specificity for the surfactant phospholipid DPPC. It plays a crucial role in the innate immune responses of the upper airways, reducing surface tension, inhibiting biofilm formation by pathogenic bacteria, and negatively regulating proteolytic cleavage of SCNN1G, contributing to airway surface liquid homeostasis. BPIFA1 may also attract macrophages and neutrophils. BPIFA1 Protein, Human is the recombinant human-derived BPIFA1 protein, expressed by E. coli , with tag free.

HY-P79144

	ADAMTS13 Protein, Human (CHO, His) ADAM-TS 13; ADAM-TS13; ADAMTS-13von Willebrand factor-cleaving protease; vWF-CP; vWF-cleaving protease; A Disintegrin-like and Metalloproteinase Domain with Thrombospondin Motifs 13	Human	CHO
	The ADAMTS13 protein, a metalloproteinase, has a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif. It cleaves von Willebrand Factor and defects in this gene cause thrombotic thrombocytopenic purpura. Alternative splicing generates multiple transcript variants. ADAMTS13 is broadly expressed in various tissues, including the liver, testis, and 24 other tissues. ADAMTS13 Protein, Human (CHO, His) is the recombinant human-derived ADAMTS13, expressed by CHO, with C-10His labeled tag. The total length of ADAMTS13 Protein, Human (CHO, His) is 655 a.a.*.

HY-P70301

	Mucin-1/MUC1 Protein, Human (HEK293, Fc) rHuMucin-1, Fc; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD227; MUC1	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (HEK293, Fc) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72399

	Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, Fc-Avi) MUC-1; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; PUM; PEM; EMA; CD227; MUC1	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag.

HY-P704178

	Mucin-1/MUC1 Protein, Mouse (HEK293, His) rHuMucin-1, Fc; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD227; MUC1	Mouse	HEK293
	Mucin-1/MUC1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Mucin-1/MUC1 protein, expressed by HEK293, with C-His tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82661

	von Willebrand Factor Antibody (YA2406) VWF; von Willebrand factor; von Willebrand antigen II; F8VWF	WB, IHC-P	Rat
	von Willebrand Factor Antibody (YA2406) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2406), targeting von Willebrand Factor, with a predicted molecular weight of 309 kDa (observed band size: 309 kDa). von Willebrand Factor Antibody (YA2406) can be used for WB, IHC-P experiment in rat background.

HY-P83341

	Mucin 1 Antibody (YA3086) MUC1; PUM; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated ep	WB, IHC-P, ICC/IF, IP, FC	Human
	Mucin 1 Antibody (YA3086) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3086), targeting Mucin 1, with a predicted molecular weight of 122 kDa (observed band size: 18-25 kDa). Mucin 1 Antibody (YA3086) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human background.

HY-P85259

	Lipocalin-1 Antibody (YA4951) LCN1; VEGP; Lipocalin-1; Tear lipocalin; Tlc; Tear prealbumin; TP; von Ebner gland protein; VEG protein	WB, IHC-P, ICC/IF, ELISA	Human
	Lipocalin-1 Antibody (YA4951) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Lipocalin-1. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human.

HY-P84932

	Mucin 1 Antibody MUC1; PUM; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated ep	IHC-P, ICC/IF, ELISA	Human
	Mucin 1 Antibody is a rabbit-derived non-conjugated IgG antibody , targeting Mucin 1, . Mucin 1 Antibody can be used for WB, IHC-P, ICC/IF,ELISA experiment in human background.

HY-P86024

	Mucin 1 Antibody (YA5716) Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD antigen CD227; [Cleaved into: Mucin-1 subunit alpha; MUC1-NT; MUC1-alpha; Mucin-1 subunit beta; MUC1-beta; MUC1-CT; ]	IHC-P, ELISA	Human
	Mucin 1 Antibody (YA5716) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 1. It can be applicated for IHC-P, ELISA assays, in the background of human.

HY-P85834

	Mucin 1 Antibody (YA5526) ADMCKD; ADMCKD1; Breast carcinoma associated antigen DF3; Breast carcinoma-associated antigen DF3; CA 15-3; CA15 3; CA15 3 antigen; CA15-3; CA15.3; Cancer antigen 15-3; Carcinoma associated mucin; Carcinoma-associated mucin; CD 227; CD227; DF3 antigen; EMA; Episialin; Epithelial Membrane Antigen; H23 antigen; H23AG; KL 6; KL-6; KL6; Krebs von den Lungen-6; MAM 6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease 1; autosomal dominant; Medullary cystic kidney disease, autosomal dominant; MUC 1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; MUC1_HUMAN; Mucin 1; Mucin 1 cell surface associated; Mucin 1 transmembrane; Mucin 1, cell surface associated; Mucin-1 subunit beta; Peanut reactive urinary mucin; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor associated epithelial membrane antigen; Tumor associated epithelial mucin; Tumor associated mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin	IHC-P, WB, ICC/IF, ELISA	Human
	Mucin 1 Antibody (YA5526) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 1. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human.

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Cat. No.	Product Name		Classification

HY-163167

VH 032 amide-alkylC5-azide		Azide
VH 032 amide-alkylC5-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand .

HY-133020

ARD-266		PROTAC Synthesis
ARD-266 is a highly potent and von Hippel-Lindau E3 ligase-based Androgen Receptor (AR) PROTAC degrader. ARD-266 effectively induces degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC₅₀ values of 0.2-1 nM . ARD-266 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-147079A

Egaptivon pegol sodium ARC 1779 sodium		Aptamers
Egaptivon pegol sodium is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol sodium has anti-thrombotic efficacy.

HY-153999A

BT200 sodium		Aptamers
BT200 sodium, a pegylated form of the aptamer BT100, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .

HY-153999

BT200		Aptamers
BT200, a pegylated form of the aptamer BT100, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .

HY-153998

BT100 sodium		Aptamers
BT100 (sodium), a aptamer, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .

HY-147079

Egaptivon pegol ARC 1779		Aptamers
Egaptivon pegol (ARC1779) is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol has anti-thrombotic efficacy.

HY-156501

BT101 sodium		Aptamers
BT101 (sodium), a complementary aptamer, has been developed to specifically inhibit BT100 function. BT100, a aptamer, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis .

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