Mucin 1 Antibody

Mucin 1 Antibody is a rabbit-derived non-conjugated IgG antibody , targeting Mucin 1, . Mucin 1 Antibody can be used for WB, IHC-P, ICC/IF,ELISA experiment in human background.

The related gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. The protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. The protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of The protein have been associated with carcinomas. The related gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

P15941-8

Non-conjugated

Unmodified

Polyclonal

Rabbit

Human

IHC: 1:20-1:200; IF: 1:50-1:200; ELISA: 1: 2000-1:5000

IHC-P, ICC/IF, ELISA

Liquid

Supplied in : 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Recombinant Human Mucin-1 protein P15941-8 (24-273AA).