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Results for "

uPAR

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Integrin (1) PAI-1 (1) Radionuclide-Drug Conjugates (RDCs) (1) Ser/Thr Protease (2) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (5) Inflammation/Immunology (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1615

Cenupatide	Transmembrane Glycoprotein	Cancer
Cenupatide (UPARANT) is a Urokinase-type plasminogen activator receptor (uPAR) inhibitor. Cenupatide has anti-angiogenic and anti-inflammatory efficacy .

HY-111192

IPR-803 2 Publications Verification	Ser/Thr Protease	Cancer
IPR-803 is a potent inhibitor of the uPAR·uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity .

HY-P2230

Angstrom6 A6 Peptide	PAI-1	Cancer
Angstrom6 (A6 Peptide) is an 8 amino-acid peptide derived from single-chain urokinase plasminogen activator (scuPA) and interferes with the *uPA/uPAR* cascade and abrogates downstream effects. Angstrom6 binds to CD44 resulting in the inhibition of migration, invasion, and metastasis of tumor cells, and the modulation of CD44-mediated cell signaling .

HY-P5018

NOTA-AE105	Radionuclide-Drug Conjugates (RDCs) Ser/Thr Protease	Cancer
NOTA-AE105 is an PET ligand of urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled by ⁶⁴Cu and ⁶⁸Ga. ⁶⁸Ga-NOTA-AE105 and ⁶⁴Cu-NOTA-AE105 shows high image contrast, resulting in clear tumor delineation . NOTA-AE105 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P990552A

huATN-658 MNPR-101	Integrin	Cancer
huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting urokinase-type plasminogen activator receptor (uPAR). huATN-658 blocks the interaction between uPAR and integrins, inhibiting the proliferation, invasion and migration of tumor cells. huATN-658 is promising for research of breast cancer (especially triple-negative breast cancer) .

Cat. No.	Product Name	Target	Research Area

HY-P1615

Cenupatide	Transmembrane Glycoprotein	Cancer
Cenupatide (UPARANT) is a Urokinase-type plasminogen activator receptor (uPAR) inhibitor. Cenupatide has anti-angiogenic and anti-inflammatory efficacy .

HY-P2230

Angstrom6 A6 Peptide	PAI-1	Cancer
Angstrom6 (A6 Peptide) is an 8 amino-acid peptide derived from single-chain urokinase plasminogen activator (scuPA) and interferes with the *uPA/uPAR* cascade and abrogates downstream effects. Angstrom6 binds to CD44 resulting in the inhibition of migration, invasion, and metastasis of tumor cells, and the modulation of CD44-mediated cell signaling .

HY-P5018

NOTA-AE105	Radionuclide-Drug Conjugates (RDCs) Ser/Thr Protease	Cancer
NOTA-AE105 is an PET ligand of urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled by ⁶⁴Cu and ⁶⁸Ga. ⁶⁸Ga-NOTA-AE105 and ⁶⁴Cu-NOTA-AE105 shows high image contrast, resulting in clear tumor delineation . NOTA-AE105 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

Cat. No.	Product Name	Target	Research Area

HY-P990552

ATN-658	Inhibitory Antibodies	Inflammation/Immunology
ATN-658 is a mouse-derived IgG antibody expressed in CHO cells that targets *PLAUR/uPAR/CD87*. ATN-658 contains muIgG1 heavy chain and mκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for ATN-658 can be referenced as Mouse IgG1 kappa, Isotype Control (HY-P99977).

HY-P990552A

huATN-658 MNPR-101	Integrin	Cancer
huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting urokinase-type plasminogen activator receptor (uPAR). huATN-658 blocks the interaction between uPAR and integrins, inhibiting the proliferation, invasion and migration of tumor cells. huATN-658 is promising for research of breast cancer (especially triple-negative breast cancer) .

Species:	Human (9) Mouse (4) Rat (1) Cynomolgus (1)
Tag:	His (14) Avi (5) GST (1) Fc (1)
Source:	HEK293 (14) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P72433

	uPAR Protein, Human (HEK293, His) Urokinase plasminogen activator surface receptor; U-PAR; CD87; PLAUR; MO3	Human	HEK293
	The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. uPAR Protein, Human (HEK293, His) is the recombinant human-derived uPAR protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77276

	uPAR Protein, Mouse (HEK293, His) Urokinase plasminogen activator surface receptor; U-PAR; CD87; PLAUR; MO3	Mouse	HEK293
	The uPAR protein acts as a receptor for urokinase plasminogen activator, facilitating plasmin formation and signal transduction activation.It interacts with SRPX2 and forms a monomer.uPAR also interacts with MRC2 and SORL1, reducing PLAUR internalization.Additionally, the PLAUR-PLAU-SERPINE1 complex interacts with SORL1.uPAR Protein, Mouse (HEK293, His) is the recombinant mouse-derived uPAR protein, expressed by HEK293 , with C-His labeled tag.

HY-P77275

	uPAR Protein, Mouse (HEK293, His-Fc) Urokinase plasminogen activator surface receptor; U-PAR; CD87; PLAUR; MO3	Mouse	HEK293
	uPAR (urokinase plasminogen activator receptor) possesses enzyme, protein, and receptor binding activities.It regulates apoptotic signaling, epidermal growth factor signaling, and cytochrome c release.uPAR is widely expressed in structures like decidua and spleen.Its human ortholog, PLAUR, is linked to rheumatoid arthritis.Investigating uPAR can reveal its role in cellular processes and shed light on diseases like rheumatoid arthritis.uPAR Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived uPAR protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

HY-P700848

	uPAR Protein, Mouse (Biotinylated, HEK293, His-Avi) U-PAR; uPAR; CD87; PLAUR; MO3; uPAR	Mouse	HEK293
	The uPAR protein acts as a receptor for urokinase plasminogen activator, facilitating plasmin formation and signal transduction activation. It interacts with SRPX2 and forms a monomer. uPAR also interacts with MRC2 and SORL1, reducing PLAUR internalization. Additionally, the PLAUR-PLAU-SERPINE1 complex interacts with SORL1. uPAR Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived uPAR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P700897

	uPAR Protein, Cynomolgus (HEK293, His) U-PAR; uPAR; CD87; PLAUR; MO3; uPAR	Cynomolgus	HEK293
	uPAR protein is the receptor of urokinase plasminogen activator and plays an important role in localizing and promoting the formation of plasmin. It mediates proteolysis-independent signal transduction through U-PA and is regulated through negative feedback. uPAR Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived uPAR protein, expressed by HEK293 , with C-His labeled tag.

HY-P700844

	uPAR Protein, Human (HEK293, His-Avi) U-PAR; uPAR; CD87; PLAUR; MO3; uPAR	Human	HEK293
	The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. uPAR Protein, Human (HEK293, His-Avi) is the recombinant human-derived uPAR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P700849

	uPAR Protein, Mouse (HEK293, His-Avi) U-PAR; uPAR; CD87; PLAUR; MO3; uPAR	Mouse	HEK293
	The uPAR protein acts as a receptor for urokinase plasminogen activator, facilitating plasmin formation and signal transduction activation. It interacts with SRPX2 and forms a monomer. uPAR also interacts with MRC2 and SORL1, reducing PLAUR internalization. Additionally, the PLAUR-PLAU-SERPINE1 complex interacts with SORL1. uPAR Protein, Mouse (HEK293, His-Avi) is the recombinant mouse-derived uPAR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P700843

	uPAR Protein, Human (Biotinylated, HEK293, His-Avi) U-PAR; uPAR; CD87; PLAUR; MO3; uPAR	Human	HEK293
	The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. uPAR Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived uPAR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P700846

	uPAR Protein, Human (Domain 1, HEK293, His) U-PAR; uPAR; CD87; PLAUR; MO3; uPAR	Human	HEK293
	The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. uPAR Protein, Human (Domain 1, HEK293, His) is the recombinant human-derived uPAR protein, expressed by HEK293 , with C-His labeled tag.

HY-P700847

	uPAR Protein, Human (Domain 3, HEK293, His) U-PAR; uPAR; CD87; PLAUR; MO3; uPAR	Human	HEK293
	The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. uPAR Protein, Human (Domain 3, HEK293, His) is the recombinant human-derived uPAR protein, expressed by HEK293 , with C-His labeled tag.

HY-P700845

	uPAR Protein, Human (Domain 2&3 , HEK293, His) U-PAR; uPAR; CD87; PLAUR; MO3; uPAR	Human	HEK293
	The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. uPAR Protein, Human (Domain 2&3, HEK293, His) is the recombinant human-derived uPAR protein, expressed by HEK293 , with C-His labeled tag.

HY-P702769

	uPAR Protein, Human (GST) Urokinase plasminogen activator surface receptor; U-PAR; CD87; PLAUR; MO3	Human	E. coli
	The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. uPAR Protein, Human (GST) is the recombinant human-derived uPAR protein, expressed by E. coli , with N-GST labeled tag.

HY-P703682

	uPAR/PLAUR Protein, Rat (HEK293, His, Avi) Urokinase plasminogen activator surface receptor; Plaur; U-PAR	Rat	HEK293

HY-P701297

	*FITC-Labeled uPAR* Protein, Human (HEK293, His)** uPAR; PLAUR; CD87; MO3	Human	HEK293
	The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. FITC-Labeled uPAR Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled uPAR protein, expressed by HEK293 , with His labeled tag.

HY-P700875

	MRC2 Protein, Human (HEK293, His) C-type lectin domain family 13 member E, Endocytic receptor 180, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein (uPAR-associated protein; Urokinase receptor-associated protein)	Human	HEK293
	The MRC2 protein may function as an endocytic lectin receptor with calcium-dependent lectin activity. It internalizes glycosylated ligands via clathrin-mediated endocytosis and releases them in endosomes. MRC2 Protein, Human (HEK293, His) is the recombinant human-derived MRC2 protein, expressed by HEK293 , with C-His labeled tag.

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HY-P81512A

	uPAR Antibody U-PAR; Monocyte activation antigen Mo3; CD87	WB, IHC-P	Human

HY-P81512

	uPAR Antibody (YA1257) U-PAR; Monocyte activation antigen Mo3; CD87	IHC-P	Human
	uPAR Antibody (YA1257) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1257), targeting uPAR. uPAR Antibody (YA1257) can be used for IHC-P experiment in human background.

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