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Results for "

trimers

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Apoptosis (3) Caspase (1) DNA/RNA Synthesis (4) Drug Derivative (1) Drug Isomer (1) E1/E2/E3 Enzyme (4) E3 Ligase Ligand-Linker Conjugates (1) EGFR (1) Epigenetic Reader Domain (10) Ferroptosis (1) Fluorescent Dye (1) GSK-3 (1) HIV (1) Isotope-Labeled Compounds (1) Ligands for E3 Ligase (2) Molecular Glues (2) NO Synthase (1) Nucleoside Antimetabolite/Analog (2) Opioid Receptor (1) Phosphatase (1) Phospholipase (1) Polo-like Kinase (PLK) (1) PROTAC Linkers (1) PROTACs (4) Reference Standards (1) Small Interfering RNA (siRNA) (112) STING (1) TNF Receptor (8)
By Research Areas:	Cancer (29) Infection (2) Inflammation/Immunology (8) Neurological Disease (3)
Oligonucleotides:	Nucleoside Phosphoramidites (1) Aptamers (1) Rat Pre-designed siRNA Sets (28) Cytosine (1) Mouse Pre-designed siRNA Sets (29) Human Pre-designed siRNA Sets (55) siRNAs (112)

158

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

114

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-156454

UCB-6876	TNF Receptor	Inflammation/Immunology
UCB-6876 is a TNFα inhibitor. UCB-6876 can specifically bind to the asymmetric crystalline form of the TNF-α trimer, with a K_D of 22 μM .

HY-W008849

DMT-dC(bz) Phosphoramidite	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Others
DMT-dC(bz) Phosphoramidite is a deoxycytidine phosphoramide monomer with a protective group. DMT-dC(bz) Phosphoramidite is commonly used for synthesizing DNA dimers or trimers .

HY-133122

UCB-9260 2 Publications Verification	TNF Receptor	Inflammation/Immunology Cancer
UCB-9260, an orally active compound, inhibits TNF signaling by stabilising an asymmetric form of the trimer. UCB-9260 is selective for TNF over other superfamily members, and binds TNF with a similar K_d of 13 nM .

HY-139324

Cu(II)GTSM 1 Publications Verification	GSK-3 Amyloid-β	Neurological Disease Cancer
Cu(II)GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3β. Cu(II)GTSM inhibits Amyloid-β oligomers (AβOs) and decreases tau phosphorylation. Cu(II)GTSM also decreases the abundance of Amyloid-β trimers. Cu(II)GTSM is a potential anticancer and antimicrobial agent .

HY-143332

TRIM24/BRPF1-IN-2	Epigenetic Reader Domain	Cancer
TRIM24/BRPF1-IN-2 (compound 20l) is a potent *TRIM24/BRPF1* dual inhibitor, with IC₅₀ values of 0.98 and 1.16 μM, respectively. TRIM24/BRPF1-IN-2 shows TRIM24/BRPF1 bromodomain binding affinity. TRIM24/BRPF1-IN-2 can be used for prostate cancer research .

HY-138165

Ac-Phe-NH2	E1/E2/E3 Enzyme	Others
Ac-Phe-NH2 is a non-competitive inhibitor of polyubiquitin chain elongation at K_i value of 8 mM by destabilizing the active trimer .

HY-162119

PRL-IN-1	Phosphatase	Cancer
PRL-IN-1 (compound 43) is a phosphatase of regenerating liver (PRL) inhibitor that directly binds the PRL1 trimer interface and obstructs PRL1 trimerization. PRL-IN-1 shows potent anticancer activities .

HY-159082

E3 ligase Ligand 28	Ligands for E3 Ligase	Cancer
TRIM7-IN-1 (compound89) is a potent *TRIM7* inhibitor with a K_D value of 2.6 µM .

HY-174853

TRIM25 ligand-1	E1/E2/E3 Enzyme	Others
TRIM25 ligand-1 (Compound 10) is a covalent ligand. TRIM25 ligand-1 can covalently bind to Cys498 in the PRYSPRY domain of *TRIM25* and enhance its auto-ubiquitination activity. TRIM25 ligand-1 is selective for *TRIM25* in vitro and in live cells .

HY-Z4561S

*Bortezomib trimer-d15*	Isotope-Labeled Compounds	Others
Bortezomib trimer-d₁₅ is deuterium labeled Bortezomib trimer.

HY-102000A

IACS-9571 TFA ASIS-P040 TFA	Epigenetic Reader Domain	Cancer
IACS-9571 (trifluoroacetate) is a potent and selective inhibitor of *TRIM24* and BRPF1, with IC₅₀ of 8 nM for TRIM24, and K_d of 31 nM and 14 nM for TRIM24 and BRPF1, respectively.

HY-102000

IACS-9571 ASIS-P040	Epigenetic Reader Domain	Cancer
IACS-9571 is a potent and selective inhibitor of *TRIM24* and BRPF1, with IC₅₀ of 8 nM for TRIM24, and K_ds of 31 nM and 14 nM for TRIM24 and BRPF1, respectively.

HY-102000B

IACS-9571 hydrochloride 1 Publications Verification ASIS-P040 hydrochloride	Epigenetic Reader Domain	Cancer
IACS-9571 (ASIS-P040) hydrochloride is a potent and selective inhibitor of *TRIM24* and BRPF1, with an IC₅₀ of 8 nM for TRIM24, and K_ds of 31 nM and 14 nM for TRIM24 and BRPF1, respectively .

HY-122626

*BRPF1B/TRIM24-IN-1*	Epigenetic Reader Domain	Cancer
BRPF1B/TRIM24-IN-1 (compound 34) is a potent *TRIM24/BRPF1/BRPF2* inhibitor, with IC₅₀ values of 0.43, 0.34, 1.75 μM, respectively. BRPF1B/TRIM24-IN-1 binds the TRIM24 bromodomain with a K_D of 222 nM and has a K_D for the BRPF1 bromodomain of 137 nM and for BRD1 of 1130 nM .

HY-111519

dTRIM24 Maximum Cited Publications 8 Publications Verification	PROTACs Epigenetic Reader Domain	Cancer
dTRIM24 is a selective bifunctional degrader of *TRIM24* based on PROTAC, consists of ligands for von Hippel-Lindau and *TRIM24*.

HY-160068

2-2(t) aptamer sodium	EGFR	Cancer
2-2(t) aptamer sodium is a 42-nucleotide trimeric complex of aptamer (2-2) targeting ErbB-2. 2-2(t) aptamer sodium inhibits the growth of gastric cancer cells in vitro and in vivo .

HY-RS15062

TRIM62 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM62 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM62 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM62 Human Pre-designed siRNA Set A TRIM62 Human Pre-designed siRNA Set A

HY-RS28312

Trim8 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Trim8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trim8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trim8 Rat Pre-designed siRNA Set A Trim8 Rat Pre-designed siRNA Set A

HY-RS15023

TRIM15 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM15 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM15 Human Pre-designed siRNA Set A TRIM15 Human Pre-designed siRNA Set A

HY-RS15067

TRIM67 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM67 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM67 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM67 Human Pre-designed siRNA Set A TRIM67 Human Pre-designed siRNA Set A

HY-RS15019

TRIM10 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM10 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM10 Human Pre-designed siRNA Set A TRIM10 Human Pre-designed siRNA Set A

HY-RS15066

TRIM66 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM66 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM66 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM66 Human Pre-designed siRNA Set A TRIM66 Human Pre-designed siRNA Set A

HY-RS15058

TRIM58 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM58 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM58 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM58 Human Pre-designed siRNA Set A TRIM58 Human Pre-designed siRNA Set A

HY-RS15072

TRIM8 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM8 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM8 Human Pre-designed siRNA Set A TRIM8 Human Pre-designed siRNA Set A

HY-RS28479

Trim44 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Trim44 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trim44 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trim44 Rat Pre-designed siRNA Set A Trim44 Rat Pre-designed siRNA Set A

HY-RS15029

TRIM24 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM24 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM24 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM24 Human Pre-designed siRNA Set A TRIM24 Human Pre-designed siRNA Set A

HY-RS15048

TRIM44 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM44 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM44 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM44 Human Pre-designed siRNA Set A TRIM44 Human Pre-designed siRNA Set A

HY-RS15042

TRIM38 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM38 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM38 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM38 Human Pre-designed siRNA Set A TRIM38 Human Pre-designed siRNA Set A

HY-RS28477

Trim31 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Trim31 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trim31 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trim31 Rat Pre-designed siRNA Set A Trim31 Rat Pre-designed siRNA Set A

HY-RS27117

Trim23 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Trim23 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trim23 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trim23 Rat Pre-designed siRNA Set A Trim23 Rat Pre-designed siRNA Set A

HY-RS15049

TRIM45 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM45 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM45 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM45 Human Pre-designed siRNA Set A TRIM45 Human Pre-designed siRNA Set A

HY-RS15063

TRIM63 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM63 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM63 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM63 Human Pre-designed siRNA Set A TRIM63 Human Pre-designed siRNA Set A

HY-RS15031

TRIM26 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM26 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM26 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM26 Human Pre-designed siRNA Set A TRIM26 Human Pre-designed siRNA Set A

HY-RS15035

TRIM3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM3 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM3 Human Pre-designed siRNA Set A TRIM3 Human Pre-designed siRNA Set A

HY-RS15061

TRIM60 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM60 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM60 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM60 Human Pre-designed siRNA Set A TRIM60 Human Pre-designed siRNA Set A

HY-RS19824

Trim27 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Trim27 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trim27 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trim27 Mouse Pre-designed siRNA Set A Trim27 Mouse Pre-designed siRNA Set A

HY-RS15030

TRIM25 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM25 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM25 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM25 Human Pre-designed siRNA Set A TRIM25 Human Pre-designed siRNA Set A

HY-RS15068

TRIM69 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM69 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM69 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM69 Human Pre-designed siRNA Set A TRIM69 Human Pre-designed siRNA Set A

HY-RS15044

TRIM4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM4 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM4 Human Pre-designed siRNA Set A TRIM4 Human Pre-designed siRNA Set A

HY-RS15022

TRIM14 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM14 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM14 Human Pre-designed siRNA Set A TRIM14 Human Pre-designed siRNA Set A

HY-RS15020

TRIM11 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM11 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM11 Human Pre-designed siRNA Set A TRIM11 Human Pre-designed siRNA Set A

HY-RS26703

Trim29 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Trim29 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trim29 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trim29 Rat Pre-designed siRNA Set A Trim29 Rat Pre-designed siRNA Set A

HY-115768A

*Compound 48/80 (trimer)* Poly-p-methoxyphenethylmethylamine (trimer)	Phospholipase	Others
Compound 48/80 (trimer) is a trimer of Compound 48/80 (HY-115768). Compound 48/80 is widely used in animal and tissue models as a "selective" mast cell activator .

HY-RS15057

TRIM56 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM56 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM56 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM56 Human Pre-designed siRNA Set A TRIM56 Human Pre-designed siRNA Set A

HY-RS15054

TRIM52 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM52 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM52 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM52 Human Pre-designed siRNA Set A TRIM52 Human Pre-designed siRNA Set A

HY-RS15064

TRIM64 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM64 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM64 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM64 Human Pre-designed siRNA Set A TRIM64 Human Pre-designed siRNA Set A

HY-RS15047

TRIM43 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM43 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM43 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM43 Human Pre-designed siRNA Set A TRIM43 Human Pre-designed siRNA Set A

HY-RS20199

Trim29 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Trim29 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trim29 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trim29 Mouse Pre-designed siRNA Set A Trim29 Mouse Pre-designed siRNA Set A

HY-RS15045

TRIM40 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRIM40 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIM40 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRIM40 Human Pre-designed siRNA Set A TRIM40 Human Pre-designed siRNA Set A

HY-RS19081

Trim62 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Trim62 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trim62 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trim62 Mouse Pre-designed siRNA Set A Trim62 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Type

HY-W008849

DMT-dC(bz) Phosphoramidite	Gene Sequencing and Synthesis
DMT-dC(bz) Phosphoramidite is a deoxycytidine phosphoramide monomer with a protective group. DMT-dC(bz) Phosphoramidite is commonly used for synthesizing DNA dimers or trimers .

HY-W013059R

DMT-dA(bz) Phosphoramidite (Standard) DA-CE phosphoramidite (Standard)	Gene Sequencing and Synthesis
DMT-dA(bz) Phosphoramidite (Standard) is the analytical standard of DMT-dA(bz) Phosphoramidite. This product is intended for research and analytical applications. DMT-dA(bz) Phosphoramidite is a phosphoramide monomer for the synthesis of oligonucleotides (ONs) through formation of DNA dimers and trimers via mechanochemistry .

Cat. No.	Product Name	Target	Research Area

HY-P3385

Rilunermin alfa SCB-313	Drug Derivative Apoptosis	Cancer
Rilunermin alfa (SCB-313) is a recombinant fusion protein composed of the human C-propeptide of alpha1(I) collagen (Trimer-Tag) to the C-terminus of the mature human tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL; Apo2L). Rilunermin alfa has potential pro-apoptotic and antineoplastic activities .

Cat. No.	Product Name	Target	Research Area

HY-P99934

Eftozanermin alfa 1 Publications Verification ABBV-621	Apoptosis Caspase TNF Receptor	Cancer
Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with K_ds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .

HY-P3385

Rilunermin alfa SCB-313	Drug Derivative Apoptosis	Cancer
Rilunermin alfa (SCB-313) is a recombinant fusion protein composed of the human C-propeptide of alpha1(I) collagen (Trimer-Tag) to the C-terminus of the mature human tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL; Apo2L). Rilunermin alfa has potential pro-apoptotic and antineoplastic activities .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3540

Caraphenol A	Leguminosae Phenols Polyphenols Plants Caragana sinica (Buchoz) Rehd.	Others
Caraphenol A is a resveratrol trimer and is able to transiently reduce interferon-induced transmembrane (IFITM) protein expression. Caraphenol A safely enhances lentiviral vector gene delivery to hematopoietic stem and progenitor cells . Caraphenol A also inhibits human cystathionine β-synthase (hCBS) and human cystathionine γ- lyase (hCSE) with IC₅₀s of 5.9 μM and 12.1 μM, respectively .

HY-N9867

Gnetifolin E	Structural Classification Source classification Phenols Polyphenols Gnetaceae Plants Gnetum gnemon var. brunonianum (Griff.) Markgr.	TNF Receptor
Gnetifolin E is a resveratrol trimer derivative that can be isolated from Gnetum brunonianum. Gnetifolin E has anti-inflammatory activity, and inhibits TNF-α .

HY-129133

cis-Miyabenol C	Structural Classification Source classification Vitis vinifera cv. Zalema Phenols Plants Vitaceae	Drug Isomer
cis-Miyabenol C is an isomer of the resveratrol trimer Miyabenol C, which can be isolated from grape herbs. Miyabenol C is an inhibitor of β-amyloid (Aβ) and amyloid β precursor protein (APP) in Alzheimer's disease model mice, and inhibit β-secretase activity without changing the protein level of β-secretase BACE1 .

Cat. No.	Product Name	Chemical Structure