Search Result
Results for "
tobacco
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
10
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-W004515
-
|
Endogenous Metabolite
|
Others
|
3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .
|
-
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- HY-W015806
-
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Endogenous Metabolite
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Others
|
3-Pyridineacetic acid is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .
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-
-
- HY-121999
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(Z)-Abienol
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Bacterial
|
Infection
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(+)-cis-Abienol (Compound Z-abienol), a diterpenoid, can be isolated from leaves of tobacco. (+)-cis-Abienol inhibits hyphal growth of P. nicotianae .
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-
-
- HY-N8024
-
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TMV
|
Infection
|
Rubinaphthin A is a naphthohydroquinone that can be found in the roots of Rubia yunnanensis. Rubinaphthin A exhibits inhibitory activity against tobacco mosaic virus (TMV) .
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-
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- HY-B1673
-
|
Bacterial
|
Infection
Cancer
|
D-Lactose monohydrate is a sugar. D-Lactose monohydrate can be utilized by most bacteria. D-Lactose monohydrate promotes the growth of tobacco B6S3 tumor tissue. D-Lactose monohydrate is used in the research of the growth mechanism of plant tumor tissues and the sugar utilization of bacteria .
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-
-
- HY-W001909
-
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nAChR
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Metabolic Disease
|
Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
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-
-
- HY-135862
-
|
Insecticide
|
Infection
|
Tetraniliprole is an insecticide that can be used in the study of tobacco cutworms (TCW) .
|
-
-
- HY-152259
-
|
TMV
|
Infection
|
TMV-IN-4 (compound 3) is a tobacco mosaic virus (TMV) inhibitor that effectively induces resistance and enhances plant tolerance to TMV infection by interacting with TMV helicase. TMV-IN-4 enhances peroxidase and superoxide dismutase activity, thereby increasing resistance to TMV in tobacco .
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-
-
- HY-N1836
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3-Hydroxy-3-acetonyloxindole
|
TMV
|
Infection
|
3-Acetonyl-3-hydroxyoxindole (AHO) is a potent systemic acquired resistance (SAR) inducer in plants. 3-Acetonyl-3-hydroxyoxindole induces resistance in tobacco plants against infection with tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole increases the level of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation and phenylalanine ammonia-lyase activity .
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-
-
- HY-W004515R
-
|
Endogenous Metabolite
|
Others
|
3-Pyridylacetic acid (hydrochloride) (Standard) is the analytical standard of 3-Pyridylacetic acid (hydrochloride). This product is intended for research and analytical applications. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .
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-
-
- HY-W331198
-
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Insecticide
|
Infection
|
Tralopyril is an insecticide that has significant insecticidal activity against pests like the tobacco budworm, two-spotted spider mite, and potato leafhopper, but it is highly toxic to plants .
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-
-
- HY-126047
-
|
Biochemical Assay Reagents
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Others
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(S)-(-)-Anatabine is a Ti plasmid mutant.
(S)-(-)-Anatabine has the activity of inducing tobacco blastoma to transform
into nicotinic alkaloids. (S)-(-)-Anatabine can be used in the study of
biotransformation of cotyl teratoma .
|
-
-
- HY-155044
-
|
TMV
Fungal
|
Infection
|
TMV-IN-5 (compound 1a) is an anti-plant virus/fungal agent. TMV-IN-5 inhibits viral assembly by binding to tobacco mosaic virus (TMV) CP. TMV-IN-5 can be used in the development of pesticides .
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-
-
- HY-W001909R
-
|
nAChR
|
Metabolic Disease
|
Myosmine (Standard) is the analytical standard of Myosmine. This product is intended for research and analytical applications. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
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-
-
- HY-131844
-
N6-Benzoyladenosine-5'-O-monophosphate
|
Endogenous Metabolite
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Others
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6-Bnz-5'-AMP is a lipophilic analogue of adenosine-5'-O-monophosphate and a potential metabolite of N 6-Benzoyl-cAMP. 6-Bnz-5'-AMP exhibits some cytokinin activity in tobacco and soybean tissue culture assays .
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-
-
- HY-118614
-
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Drug Metabolite
|
Neurological Disease
|
β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .
|
-
-
- HY-N12249
-
|
Amyloid-β
TMV
|
Infection
Neurological Disease
Inflammation/Immunology
|
7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice .
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-
-
- HY-119458
-
|
Topoisomerase
TMV
Fungal
|
Infection
|
Luotonin A is an antiviral and antiphytopathogenic fungus agent. Luotonin A has good antiviral activity against tobacco mosaic virus (TMV). Luotonin A also has certain inhibitory activity on topoisomerase I and topoisomerase II. Luotonin A shows antitumor activity .
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-
-
- HY-145324
-
|
TMV
|
Infection
|
Antiviral agent 14 is an antiviral agent against the tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). The EC50 values of Antiviral agent 14 against TMV and CMV with EC50 values of 135.5 μg/mL and 178.6 μg/mL, respectively .
|
-
-
- HY-148569
-
|
TMV
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
TMV-IN-3, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-3 has antiviral activity against TMV with an EC50 value of 120.3 μg/mL. TMV-IN-3 can be used for the research of infection, inflammation and tumor .
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-
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- HY-148568
-
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TMV
Bacterial
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Infection
Inflammation/Immunology
Cancer
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TMV-IN-2, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-2 has antiviral activity against TMV with an EC50 value of 89.9 μg/mL. TMV-IN-2 can be used for the research of infection, inflammation and tumor .
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-
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- HY-118614R
-
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Drug Metabolite
|
Neurological Disease
|
β-Nicotyrine (Standard) is the analytical standard of β-Nicotyrine. This product is intended for research and analytical applications. β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .
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-
-
- HY-N8521
-
|
TMV
Parasite
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Infection
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6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity .
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-
-
- HY-148567
-
|
TMV
Bacterial
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Infection
Inflammation/Immunology
Cancer
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TMV-IN-1, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-1 has good therapeutic activity and protective activity against TMV with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. TMV-IN-1 can be used for the research of infection, inflammation and tumor .
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-
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- HY-145476
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N-NAT; N'-Nitrosoanatabine
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Biochemical Assay Reagents
|
Cancer
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(R,S)-N-Nitrosoanatabine (N-NAT) is a tobacco-specific nitrosamine (TSNA) that has been found in tobacco, tobacco products, and electronic cigarettes. The (S) enantiomer comprises approximately 80% of the N-NAT found in commercial and research cigarettes and smokeless tobacco.3 Unlike other TSNAs, N-NAT is not carcinogenic in rats when administered at doses of 1, 3, and 9 mmol/kg.
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-
-
- HY-126047A
-
-
-
- HY-B1178R
-
|
Endogenous Metabolite
nAChR
|
Cardiovascular Disease
Inflammation/Immunology
|
Cotinine (Standard) is the analytical standard of Cotinine. This product is intended for research and analytical applications. Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke
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-
-
- HY-156533
-
|
5-HT Receptor
|
Cancer
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5-HT2 agonist-1 (Compound 24) is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. 5-HT2 agonist-1 free base can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders .
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-
-
- HY-156533A
-
|
5-HT Receptor
|
Neurological Disease
Inflammation/Immunology
Cancer
|
5-HT2 agonist-1 (Compound 24) free base is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. 5-HT2 agonist-1 free base can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders .
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-
-
- HY-156534
-
|
5-HT Receptor
|
Neurological Disease
Inflammation/Immunology
Cancer
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5-HT2A&5-HT2C agonist-1 (Example 2) is a 5-HT2A & 5-HT2C agonist, with IC50s of 196 nM and 0.9 nM respectively. 5-HT2A&5-HT2C agonist-1 can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders .
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-
-
- HY-133986
-
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Others
|
Cancer
|
6-Methylchrysene, a tobacco smoke constituent, is a weak carcinogen .
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-
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- HY-Y0189S
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Wintergreen oil-d4
|
COX
|
Inflammation/Immunology
|
Methyl Salicylate-d4 is the deuterium labeled Methyl Salicylate[1]. Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products[2]. A systemic acquired resistance (SAR) signal in tobacco[3]. A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor[5].
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-
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- HY-126047AS
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-
-
- HY-114652
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2-Amino-α-carboline; AαC
|
Endogenous Metabolite
|
Cancer
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AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits .
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-
-
- HY-133185
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-
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- HY-126047AR
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Biochemical Assay Reagents
|
Inflammation/Immunology
|
(R,S)-Anatabine (Standard) is the analytical standard of (R,S)-Anatabine (HY-126047A). This product is intended for research and analytical applications. (R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .
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-
-
- HY-N6085
-
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Others
|
Others
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N-Caffeoylputrescine,(E)- is a caffeic acid amide found in the tobacco plants (Nicotiana tabacum L.) .
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-
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- HY-N10110
-
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TMV
|
Infection
|
(±)-Phrymarolin II is a promising new class of plant virus (tobacco mosaic virus) inhibitors.
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-
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- HY-34516
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(R)-Ornithine hydrochloride
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Endogenous Metabolite
Bacterial
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Metabolic Disease
|
D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins .
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-
-
- HY-163999
-
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TMV
|
Infection
|
TMV-IN-12 (compound 4) is an inhibitor of tobacco mosaic virus (TMV) with antifungal properties. TMV-IN-12 effectively prevents TMV particle aggregation and self-assembly of TMV capsid protein (TMV-CP) (Kd=0.142 μM), preventing TMV from infecting tobacco plants .
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-
-
- HY-W679891
-
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Drug Derivative
|
Cancer
|
N-Nitroso-N-methyl-4-aminobutyric acid is a tobacco-specific nitrosamine carcinogen .
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-
-
- HY-Y0189
-
Salicylic acid methyl ester
|
COX
|
Inflammation/Immunology
|
Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products . A systemic acquired resistance (SAR) signal in tobacco . A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor .
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-
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- HY-W700491
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2-Amino-α-carboline-15N3; AαC-15N3
|
Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
|
AalphaC- 15N3 (2-Amino-α-carboline- 15N3) is 15N labeled AalphaC. AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits .
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-
-
- HY-N7532
-
|
TMV
|
Infection
|
Yadanzioside I is a potent anti-tobacco mosaic virus (TMV) quassinoid with an IC50 of 4.22 μM .
|
-
-
- HY-N7194
-
|
TMV
|
Infection
|
Yadanzioside L is a quassinoid and shows anti-tobacco mosaic virus (TMV) activity (IC50=4.86 μM) .
|
-
-
- HY-N15133
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(-)-Solanacol
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Others
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Others
|
Solanacol ((-)-Solanacol) is a plant hormone that can be isolated from tobacco (Nicotiana tabacum L.). Solanacol is the germination stimulants for parasitic plants .
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-
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- HY-W127341
-
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Biochemical Assay Reagents
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Others
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Phytanic acid methyl esteris an esterified form of long-chain fatty acid methyl esters and phytanic acid, which has been found in Greek tobacco.
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-
-
- HY-W040194
-
|
Herbicide
|
Others
|
Clomazone is a broad spectrum herbicide used for control of annual grasses and broadleaf weeds in cotton, peas, pumpkins, soybeans, sweet potatoes, and tobacco .
|
-
-
- HY-125439
-
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Others
|
Metabolic Disease
|
Squalestatin 2 is a potent squalene synthase inhibitor. Squalestatin 2 has IC50 values of 5 and 4 nM in rat liver and tobacco, respectively .
|
-
-
- HY-145731
-
Fru-Leu
|
Endogenous Metabolite
|
Others
|
Fructose-leucine (Fru-Leu) is an Amadori compound that can be found in tobacco and is a precursor of aroma formed during the early stages of the Maillard reaction .
|
-
- HY-Y0189R
-
|
COX
|
Inflammation/Immunology
|
Methyl Salicylate (Standard) is the analytical standard of Methyl Salicylate. This product is intended for research and analytical applications. Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products . A systemic acquired resistance (SAR) signal in tobacco . A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor .
|
-
- HY-E70465
-
|
Cytochrome P450
|
Metabolic Disease
|
Human CYP2A6, High-Reductase, a recombinant CYP2A6, is a member of the CYP enzyme family and is responsible for the metabolic activation of most tobacco carcinogens .
|
-
- HY-Y0507
-
|
TMV
|
Infection
Cancer
|
DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .
|
-
- HY-W683760
-
(2S)-N'-Nitrosonornicotine
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DNA/RNA Synthesis
|
Cancer
|
N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .
|
-
- HY-E70507
-
|
Cytochrome P450
|
Metabolic Disease
|
Human CYP2A6, High-Reductase+b5, a recombinant CYP2A6, is a member of the CYP enzyme family and is responsible for the metabolic activation of most tobacco carcinogens .
|
-
- HY-P10871
-
|
Virus Protease
|
Infection
|
cTEV6-2 binds to the cysteine residue (C151) of tobacco etch virus protease (TEV protease), and covalently inhibits TEV protease with an IC50 of 81.7 nM .
|
-
- HY-163201
-
|
TMV
|
Infection
|
TMV-IN-7 (compound G2) is a potent inhibitor of tobacco mosaic virus (TMV). TMV-IN-7 exhibits strong hydrophobic interactions to obstructing the virus’s self-assembly .
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-
- HY-103673
-
|
Adenosine Deaminase
|
Neurological Disease
|
AMPD2 inhibitor 1 is an adenosine monophosphate deaminase 2 (AMPD2) inhibitor, used in the research of sugar craving, salt craving, umami craving, and addictions including agent, tobacco, nicotine and alcohol addictions.
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-
- HY-126744
-
|
Parasite
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Others
|
Juncin E is a diterpenoid found in the soft coral Junceella juncea that exhibits significant insecticidal activity against the larvae of two important agricultural pests: southern corn rootworm and tobacco armyworm [2].
|
-
- HY-N12938
-
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Others
|
Endocrinology
|
(Z)-7-Hexadecenyl acetate is a pheromone used for capturing male tobacco budworm moths (Heliothis virescens), which can be isolated from the brush glands or hair pencils on the abdomen or hind wings of insects .
|
-
- HY-W004515S
-
|
Endogenous Metabolite
|
Others
|
3-Pyridylacetic acid-d4 (hydrochloride) is the deuterium labeled 3-Pyridylacetic acid hydrochloride . 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .
|
-
- HY-N4210
-
|
TMV
|
Infection
Cancer
|
Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects .
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-
- HY-135078
-
NSC 270912
|
DNA/RNA Synthesis
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Others
|
2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM).
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- HY-N15076
-
|
Src
Antibiotic
Bacterial
|
Infection
Cancer
|
Herbimycin B is an ansamycin antibiotic that acts as a Src family kinase inhibitor. Herbimycin B has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells .
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- HY-159488
-
|
Protoporphyrinogen IX oxidase
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Others
|
PPO-IN-14 (compound B11) is a Nicotiana tobacco Protoporphyrinogen oxidase (NtPPO) inhibitor, with a Ki value of 9.05 nM. PPO-IN-14 (compound B11) could help control weeds in agricultural production .
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-
- HY-W040194R
-
|
Herbicide
|
Others
|
Clomazone (Standard) is the analytical standard of Clomazone. This product is intended for research and analytical applications. Clomazone is a broad spectrum herbicide used for control of annual grasses and broadleaf weeds in cotton, peas, pumpkins, soybeans, sweet potatoes, and tobacco .
|
-
- HY-W001909S
-
|
nAChR
|
Metabolic Disease
|
Myosmine-d4 is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
|
-
- HY-137970
-
A-83543D aglycone
|
Parasite
|
Infection
|
Spinosyn D aglycone is an aglycone form of the insecticide Spinosyn D (HY-125326). Unlike spinosyn D, spinosyn D aglycone is not lethal to H. virescens (tobacco budworm) neonate larvae (LC50=>64 ppm).
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-
- HY-B1178
-
(-)-Cotinine; (S)-Cotinine; NIH-10498
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Endogenous Metabolite
nAChR
|
Cardiovascular Disease
Inflammation/Immunology
|
Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors (nAChR) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases .
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-
- HY-W017463
-
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TMV
|
Infection
|
trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid. trans-3-(3-Pyridyl)acrylic acid shows antiviral activity against tobacco mosaic virus (TMV) .
|
-
- HY-121801
-
|
Fungal
Microtubule/Tubulin
Mitosis
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Infection
|
Zarilamid is a fungicide which is active against a broad spectrum of Oomycete fungi. Zarilamid inhibits nuclear division in germinating zoospore cysts of Phytophthora capsici. Zarilamide inhibits growth of tobacco roots and causes swelling of the root tips, destructs microtubule cytoskeleton and inhibits mitosis .
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- HY-121255
-
(R)-Cryptopleurine; NSC 19912
|
TMV
|
Cancer
|
(–)-Cryptopleurine is an alkaloid that has been found in Lauraceae and has diverse biological activities. It inhibits the growth of human A375 melanoma, A431 epidermoid carcinoma, A549 lung, MES-SA uterine sarcoma, and MCF-7 breast cancer cells (IC50=3 nM for all).2 (–)-Cryptopleurine inhibits hypoxia-induced gene expression in a hypoxia response element (HRE) reporter assay (IC50=8.7 nM).3 (–)-Cryptopleurine (500 μg/mL) prevents lesion formation in tobacco (N. tabacum) plants infected with tobacco mosaic virus (TMV). It also inhibits protein synthesis by yeast and mammalian ribosomes.
|
-
- HY-Y0507R
-
|
TMV
|
Infection
Cancer
|
DL-Serine (Standard) is the analytical standard of DL-Serine. This product is intended for research and analytical applications. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].
|
-
- HY-W718796
-
|
Isotope-Labeled Compounds
TMV
|
Cancer
|
DL-Serine- 15N is 15N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
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-
- HY-N13047
-
|
Others
|
Infection
|
Ningnanmycin is a plant antiviral agent that has been found to directly bind to the coat protein (CP) of tobacco mosaic virus (TMV) and inhibit its assembly process. These interactions lead to the dissociation of the coat protein from the discoid structure into monomers,significantly reducing the pathogenicity of TMV .
|
-
- HY-N6740R
-
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Apoptosis
|
Metabolic Disease
|
(±)-Nornicotine (Standard) is the analytical standard of (±)-Nornicotine. This product is intended for research and analytical applications. (±)-Nornicotine is the primary metabolite of nicotine that is formed through demethylation of nicotine in the genus Nicotiana tabacum L. (±)-Nornicotine is a precursor of tobacco-specific nitrosamine N-nitrosonornicotine. (±)-Nornicotine has detrimental effects to human health .
|
-
- HY-135186
-
|
Biochemical Assay Reagents
|
Others
|
L-Monomenthyl glutarate is a menthol coolant. L-Monomenthyl glutarate has a strong volatility and permeability, high concentration of menthol vapor has a strong irritation and erosion effect on human skin and mucosa. L-Monomenthyl glutarate can be used in food, tobacco and other daily chemical products .
|
-
- HY-Y0507S
-
|
TMV
Isotope-Labeled Compounds
|
Infection
Cancer
|
DL-Serine-2,3,3-d3 is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].
|
-
- HY-117085
-
|
Phosphatase
TMV
Lipoxygenase
|
Cancer
|
Lobaric acid is a depsipeptide metabolite isolated from Stereocaulon lichen with antioxidant, antiproliferative, antiviral and enzyme inhibitory activities. Lobaric acid scavenges superoxide free radicals (IC50=97.9 μM) and inhibits cancer cell proliferation (EC50 of 15.2-63.9 μg/mL against leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic and lung cancer cell lines). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50=0.87 μM for human recombinant enzyme) and 12(S)-HETE produced by 12(S)-lipoxygenase (IC50=28.5 μM). Lobaric acid (250 μM) also reduced pathological changes in tobacco leaves infected with tobacco mosaic virus (TMV).
|
-
- HY-162400
-
|
TMV
|
Infection
|
TMV-IN-8 (compound 7 d) is an anti tobacco mosaic virus (TMV) agent with an antiviral EC50 of 157.6 μg/mL.TMV-IN-8 blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppressed TMV coat protein gene expression and biosynthesis process .
|
-
- HY-N12874
-
|
Others
|
Others
|
(E,E,Z)-10,12,14-Hexadecatrienal is a pheromone that can be produced by female Manduca sexta .
|
-
- HY-N12873
-
|
Others
|
Others
|
(E,E,E,)-10,12,14-Hexadecatrienal is a pheromone that can be produced by female Manduca sexta .
|
-
- HY-B1532
-
(S)-Anabasine; (+)-Anabasine
|
nAChR
|
Neurological Disease
|
Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
|
-
- HY-162807
-
|
TMV
|
Infection
|
TMV-IN-10 (compound 4h) is an arecoline derivative with anti-tobacco mosaic virus (TMV) activity (EC50=146 µg/mL). TMV-IN-10 can be used in research on controlling crop pests and diseases and improving crop yields by acting on the viral coat protein (CP) to cause viral fragmentation .
|
-
- HY-W743781
-
(2S)-N'-Nitrosonornicotine-d4
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Cancer
|
N-Nitrosonornicotine-d4 ((2S)-N'-Nitrosonornicotine-d4) is deuterium labeled N-Nitrosonornicotine. N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .
|
-
- HY-W014928
-
(S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride
|
nAChR
|
Neurological Disease
|
Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
|
-
- HY-N7434
-
Diethylnitrosamine; DEN
|
DNA/RNA Synthesis
|
Cancer
|
N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
|
-
- HY-135560
-
Nicotellin
|
Cytochrome P450
|
Neurological Disease
|
Nicotelline (Nicotellin) is a nicotine-related alkaloid, as well as a weak inhibitor of human cDNA-expressed cytochrome P-450 2A6 (CYP2A6). CYP2A6 mediates coumarin 7-hydroxylation, while Nicotelline fails to exhibit inhibition at 300 μM. Nicotelline can be used as a tracer and biomarker of particulate matter (PM) derived from tobacco smoke .
|
-
- HY-119698
-
SD 8339; N-Benzyl-9-(tetrahydro-2h-pyran-2-yl)adenine
|
Drug Derivative
|
Others
|
BAP9THP is a synthetic cytokinin derivative and a growth regulator. BAP9THP promotes chlorophyll retention (and senescence delay) in plant tissues exceptionally strongly, and growth of tobacco callus almost as strongly as 6-Benzylaminopurine (BAP). BAP9THP induces adventitious shoot formation ignificantly more strongly than N6-isopentenyladenine or Kinetin .
|
-
- HY-163754
-
|
TMV
|
Infection
|
TMV-IN-9 (compound A6) is an antiviral agent that displays excellent inactivating against tobacco mosaic virus (TMV) with an EC50 of 62.8 μg/mL. TMV-IN-9 shows strong binding capacity to TMV coat protein with a binding affinity value of 1.862 μM. TMV-IN-9 obviously destroys the integrity of the TMV particles and blocked the virus from infecting the host .
|
-
- HY-B1532R
-
|
nAChR
|
Neurological Disease
|
Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
|
-
- HY-B1673R
-
|
Bacterial
|
Infection
Cancer
|
D-Lactose monohydrate (Standard) is the analytical standard of D-Lactose monohydrate (HY-B1673). This product is intended for research and analytical applications. D-Lactose monohydrate is a sugar. D-Lactose monohydrate can be utilized by most bacteria. D-Lactose monohydrate promotes the growth of tobacco B6S3 tumor tissue. D-Lactose monohydrate is used in the research of the growth mechanism of plant tumor tissues and the sugar utilization of bacteria .
|
-
- HY-W041301R
-
|
Reference Standards
Cholinesterase (ChE)
Bacterial
|
Infection
Neurological Disease
Cancer
|
(±)-Dihydroactinidiolide (Standard) is the analytical standard of (±)-Dihydroactinidiolide (HY-W041301). This product is intended for research and analytical applications. (±)-Dihydroactinidiolide is the exo-isomer of Dihydroactinidiolide (HY-107805). Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect. Dihydroactinidiolide is also an inhibitor of AChE (IC50 = 34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis .
|
-
- HY-W041301
-
|
Cholinesterase (ChE)
Bacterial
|
Infection
Neurological Disease
Cancer
|
(±)-Dihydroactinidiolide is the exo-isomer of Dihydroactinidiolide (HY-107805). Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect. Dihydroactinidiolide is also an inhibitor of AChE (IC50 = 34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis .
|
-
- HY-P2717
-
|
Caspase
|
Infection
|
Ac-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells .
|
-
- HY-19918A
-
|
NF-κB
Amyloid-β
nAChR
|
Neurological Disease
Inflammation/Immunology
|
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. Anatabine dicitrate is a potent α4β2 nAChR agonist. Anatabine dicitrate inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine dicitrate has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment .
|
-
- HY-162376
-
|
Bacterial
|
Infection
|
T3SS-IN-4 (Compound Z-8) is a T3SS inhibitor that can inhibit the expression of Xanthomonas oryzae pv oryzae (Xoo) T3SS-related genes without affecting bacterial growth. T3SS-IN-4 can effectively reduce the hypersensitive response (HR) induced by Xoo in tobacco and lower the pathogenicity of Xoo in rice .
|
-
- HY-N7434S1
-
Diethylnitrosamine-d10; DEN-d10
|
DNA/RNA Synthesis
|
Cancer
|
N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine . N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
|
-
- HY-N7434S
-
Diethylnitrosamine-d4; DEN-d4
|
DNA/RNA Synthesis
|
Cancer
|
N-Nitrosodiethylamine-d4 is the deuterium labeled N-Nitrosodiethylamine . N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
|
-
- HY-Y1683
-
Racementhol
|
GABA Receptor
|
Neurological Disease
|
DL-Menthol (Racementhol) is an orally active, GABAaR positive allosteric modulator and UDP-glucuronosyltransferase (UGT) inhibitor that can cross the blood-brain barrier. DL-Menthol binds to GABAAR and exhibits an allosteric activation effect, enhancing GABA-mediated chloride influx and inhibiting neuronal excitability. DL-Menthol can induce surgical anesthesia in fish and inhibit the metabolic detoxification of tobacco carcinogens by human liver and intestinal UGT enzymes, resulting in reduced NNAL-N-Gluc production .
|
-
- HY-N7434R
-
Diethylnitrosamine (Standard); DEN (Standard)
|
Reference Standards
DNA/RNA Synthesis
|
Cancer
|
N-Nitrosodiethylamine (Standard) is the analytical standard of N-Nitrosodiethylamine. This product is intended for research and analytical applications. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
|
-
- HY-172151
-
|
Herbicide
Protoporphyrinogen IX oxidase
|
Others
|
PPO-IN-17 (Compound 6R) is the inhibitor protoporphyrinogen IX oxidase (PPO) that inhibits Nicotiana tobacco PPO (NtPPO) with Ki of 30.34 nM. PPO-IN-17 exhibits herbicidal activity that inhibits barnyardgrass (E. crus-galli), foxtail grass (D. sanguinalis), alfalfa (M. sativa) and Canada cocklebur (C. canadensis) (>95% inhibition rate at a concentration of 37.5 g/hm 2). PPO-IN-17 exhibits no toxicity on rice (at a concentration of 75 g/hm 2) or on honeybees (at a concentration of 6400 mg/kg) .
|
-
- HY-N0576
-
-
- HY-W017232
-
p-Quinanisole
|
Biochemical Assay Reagents
|
Others
|
6-Methoxyquinoline consists of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound occurs naturally in certain plants, such as tobacco and tea, and has been shown to have biological activities, including antioxidant, anti-inflammatory and antitumor properties. Furthermore, 6-Methoxyquinoline can be used as a building block for the synthesis of other organic compounds, especially those with potential pharmaceutical applications. Due to its ability to bind nucleic acids and proteins, it can also be used as a fluorescent probe in biochemical and biomedical research.
|
-
- HY-100958
-
4-DAMP
3 Publications Verification
4-DAMP methiodide
|
mAChR
Apoptosis
MMP
EGFR
Interleukin Related
|
Inflammation/Immunology
Cancer
|
4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion .
|
-
- HY-N0576R
-
|
Reference Standards
Endogenous Metabolite
Heme Oxygenase (HO)
HSP
p38 MAPK
Akt
Apoptosis
Caspase
PARP
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
Solanesol (Standard) is the analytical standard of Solanesol (HY-N0576). This product is intended for research and analytical applications. Solanesol is an orally active aliphatic terpene alcohol. Solanesol is mainly found in tobacco and other Solanaceae plants. Solanesol induces HO-1 and Hsp70 expression, activates p38 and Akt signaling pathways, and inhibits Apoptosis (reduces caspase-3 and PARP cleavage). Solanesol has antioxidant, anti-inflammatory, and neuroprotective activities. Solanesol can be used in the research of Huntington's disease, alcoholic liver disease, chronic inflammatory pain, anxiety, Alzheimer's disease, and bipolar disorder .
|
-
- HY-41404
-
2H-1,3-benzodioxole-5-carboxylic acid
|
Cytochrome P450
Interleukin Related
EGFR
IGF-1R
|
Infection
Others
Cancer
|
Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities .
|
-
- HY-P5712
-
Gramicidin soviet
|
Antibiotic
Bacterial
Na+/K+ ATPase
|
Infection
|
Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic that selectively targets bacterial cell membranes and has anticancer activity. Gramicidin S also exerts antibacterial activity by destroying membrane integrity and interfering with membrane protein function. Gramicidin S inserts into the phospholipid bilayer through hydrophobic amino acid residues, specifically binds to negatively charged membrane lipids and disrupts membrane structure, thereby inhibiting cell division and cell wall synthesis, and ultimately causing bacterial death. Gramicidin S also inhibits ion channels, with IC50s of 41 μM, 24 μM, and 3 μM for Na +/K +-ATPase, tobacco leaf plasma membrane Mg 2+/K +-ATPase, and rat heart plasma membrane Ca 2+-ATPase, respectively .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-W127341
-
|
Drug Delivery
|
Phytanic acid methyl esteris an esterified form of long-chain fatty acid methyl esters and phytanic acid, which has been found in Greek tobacco.
|
-
- HY-W017232
-
p-Quinanisole
|
Biochemical Assay Reagents
|
6-Methoxyquinoline consists of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound occurs naturally in certain plants, such as tobacco and tea, and has been shown to have biological activities, including antioxidant, anti-inflammatory and antitumor properties. Furthermore, 6-Methoxyquinoline can be used as a building block for the synthesis of other organic compounds, especially those with potential pharmaceutical applications. Due to its ability to bind nucleic acids and proteins, it can also be used as a fluorescent probe in biochemical and biomedical research.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5712
-
Gramicidin soviet
|
Antibiotic
Bacterial
Na+/K+ ATPase
|
Infection
|
Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic that selectively targets bacterial cell membranes and has anticancer activity. Gramicidin S also exerts antibacterial activity by destroying membrane integrity and interfering with membrane protein function. Gramicidin S inserts into the phospholipid bilayer through hydrophobic amino acid residues, specifically binds to negatively charged membrane lipids and disrupts membrane structure, thereby inhibiting cell division and cell wall synthesis, and ultimately causing bacterial death. Gramicidin S also inhibits ion channels, with IC50s of 41 μM, 24 μM, and 3 μM for Na +/K +-ATPase, tobacco leaf plasma membrane Mg 2+/K +-ATPase, and rat heart plasma membrane Ca 2+-ATPase, respectively .
|
-
- HY-P10871
-
|
Virus Protease
|
Infection
|
cTEV6-2 binds to the cysteine residue (C151) of tobacco etch virus protease (TEV protease), and covalently inhibits TEV protease with an IC50 of 81.7 nM .
|
-
- HY-P3825
-
CCAP
|
Peptides
|
Cardiovascular Disease
|
Crustacean cardioactive peptide (CCAP) is a insect cardioregulatory peptides that contmns 9 amino acid, first isolated from the tobacco hawkmoth, Manduca sexta. There are two cystemes at pnsttons 3 and 9 forming a disulfide bridge and the carboxyl-terminns is amldated .
|
-
- HY-P10244F
-
|
Peptides
|
Infection
|
Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1 .
|
-
- HY-P2717
-
|
Caspase
|
Infection
|
Ac-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W004515
-
-
-
- HY-W015806
-
-
-
- HY-121999
-
-
-
- HY-N8024
-
-
-
- HY-B1673
-
-
-
- HY-W001909
-
-
-
- HY-N1836
-
-
-
- HY-W004515R
-
-
-
- HY-W001909R
-
-
-
- HY-N12249
-
-
-
- HY-119458
-
-
-
- HY-N8521
-
-
-
- HY-B1178R
-
-
-
- HY-133185
-
-
-
- HY-N6085
-
-
-
- HY-N10110
-
-
-
- HY-34516
-
-
-
- HY-Y0189
-
-
-
- HY-N7532
-
-
-
- HY-N7194
-
-
-
- HY-N15133
-
-
-
- HY-145731
-
-
-
- HY-Y0189R
-
|
Structural Classification
Monophenols
Microorganisms
Murraya paniculata (L.) Jack.
Source classification
Rutaceae
Phenols
Plants
|
COX
|
Methyl Salicylate (Standard) is the analytical standard of Methyl Salicylate. This product is intended for research and analytical applications. Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products . A systemic acquired resistance (SAR) signal in tobacco . A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor .
|
-
-
- HY-Y0507
-
-
-
- HY-126744
-
-
-
- HY-N12938
-
-
-
- HY-N4210
-
-
-
- HY-N15076
-
-
-
- HY-B1178
-
-
-
- HY-Y0507R
-
-
-
- HY-N13047
-
-
-
- HY-N6740R
-
-
-
- HY-N12874
-
-
-
- HY-N12873
-
-
-
- HY-B1532
-
-
-
- HY-N7434
-
-
-
- HY-B1532R
-
-
-
- HY-B1673R
-
|
Structural Classification
Polysaccharides
Source classification
Endogenous metabolite
Saccharides
|
Bacterial
|
D-Lactose monohydrate (Standard) is the analytical standard of D-Lactose monohydrate (HY-B1673). This product is intended for research and analytical applications. D-Lactose monohydrate is a sugar. D-Lactose monohydrate can be utilized by most bacteria. D-Lactose monohydrate promotes the growth of tobacco B6S3 tumor tissue. D-Lactose monohydrate is used in the research of the growth mechanism of plant tumor tissues and the sugar utilization of bacteria .
|
-
-
- HY-W041301R
-
|
Structural Classification
Natural Products
Nicotiana tabacum L.
Source classification
Solanaceae
Plants
|
Reference Standards
Cholinesterase (ChE)
Bacterial
|
(±)-Dihydroactinidiolide (Standard) is the analytical standard of (±)-Dihydroactinidiolide (HY-W041301). This product is intended for research and analytical applications. (±)-Dihydroactinidiolide is the exo-isomer of Dihydroactinidiolide (HY-107805). Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect. Dihydroactinidiolide is also an inhibitor of AChE (IC50 = 34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis .
|
-
-
- HY-W041301
-
-
-
- HY-Y1683
-
-
-
- HY-N7434R
-
Diethylnitrosamine (Standard); DEN (Standard)
|
Structural Classification
Natural Products
other families
Source classification
Plants
|
Reference Standards
DNA/RNA Synthesis
|
N-Nitrosodiethylamine (Standard) is the analytical standard of N-Nitrosodiethylamine. This product is intended for research and analytical applications. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
|
-
-
- HY-N0576
-
-
-
- HY-N0576R
-
-
-
- HY-41404
-
-
Cat. No. |
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Product Name |
Species |
Source |
Compare Products
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* This product has been "discontinued".
Optimized version of product available:
|
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-126047AS
-
|
(R,S)-Anatabine-d4 is a deuterated labeled (R,S)-Anatabine (HY-126047A). (R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .
|
-
-
- HY-W001909S
-
|
Myosmine-d4 is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
|
-
-
- HY-Y0507S
-
|
DL-Serine-2,3,3-d3 is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].
|
-
-
- HY-N7434S1
-
|
N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine . N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
|
-
-
- HY-N7434S
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N-Nitrosodiethylamine-d4 is the deuterium labeled N-Nitrosodiethylamine . N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
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- HY-Y0189S
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Methyl Salicylate-d4 is the deuterium labeled Methyl Salicylate[1]. Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products[2]. A systemic acquired resistance (SAR) signal in tobacco[3]. A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor[5].
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- HY-W700491
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AalphaC- 15N3 (2-Amino-α-carboline- 15N3) is 15N labeled AalphaC. AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits .
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- HY-W004515S
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3-Pyridylacetic acid-d4 (hydrochloride) is the deuterium labeled 3-Pyridylacetic acid hydrochloride . 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .
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- HY-W718796
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DL-Serine- 15N is 15N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
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- HY-W743781
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N-Nitrosonornicotine-d4 ((2S)-N'-Nitrosonornicotine-d4) is deuterium labeled N-Nitrosonornicotine. N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .
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