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Results for "

tissue-nonspecific alkaline phosphatase

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Inhibitory Antibodies

2

Recombinant Proteins

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-78144
    4-Methylsalicylic acid

    		IAP Inflammation/Immunology
    4-Methylsalicylic acid is a salicylic acid. 4-Methylsalicylic acid derivative is a selective tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibitor .
    4-Methylsalicylic acid
  • HY-14210
    TNAP-IN-1

    		Phosphatase Inflammation/Immunology
    TNAP-IN-1 (Compound 1) is a selective tissue-nonspecific alkaline phosphatase (TNAP) inhibitor, with an IC50 of 0.19 μM. TNAP-IN-1 can be used for the research of soft tissue calcification .
    TNAP-IN-1
  • HY-124756
    SBI-425
    1 Publications Verification

    		 Phosphatase Cardiovascular Disease
    SBI-425 is an orally active and potent TNAP (tissue-nonspecific alkaline phosphatase) inhibitor (IC50=16 nM). SBI-425 inhibits TNAP in the vasculature, improving cardiovascular parameters and survival .
    SBI-425
  • HY-P991210
    Efzimfotase alfa

    ALXN-1850

    		 Phosphatase Cardiovascular Disease
    Efzimfotase alfa (ALXN-1850) is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP) .
    Efzimfotase alfa
  • HY-139852
    PLAP-IN-1

    		Phosphatase Cancer
    PLAP-IN-1 is a potent (IC50 = 32 nM) and selective PLAP inhibitor, with no detectable inhibition of tissue non-specific alkaline phosphatase (TNAP) activity.
    PLAP-IN-1

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