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Results for "

steroid hormones

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Steroid Sulfatase (1) Thyroid Hormone Receptor (1) Androgen Receptor (6) Apoptosis (3) Autophagy (11) Bacterial (3) Biochemical Assay Reagents (1) Cannabinoid Receptor (9) Cytochrome P450 (13) Drug Intermediate (1) Endogenous Metabolite (58) Estrogen Receptor/ERR (20) Glucocorticoid Receptor (13) GnRH Receptor (3) Insecticide (1) Isotope-Labeled Compounds (26) Melanocortin Receptor (3) Mineralocorticoid Receptor (3) NF-κB (1) Parasite (1) Phosphatase (1) Potassium Channel (1) Progesterone Receptor (9) Reference Standards (1) TRP Channel (9)
By Research Areas:	Cancer (44) Cardiovascular Disease (14) Endocrinology (51) Infection (1) Inflammation/Immunology (15) Metabolic Disease (16) Neurological Disease (13)
Click Chemistry:	Alkynes (2)

102

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: Steroid Sulfatase Thyroid Hormone Receptor Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-105184

YM511	Cytochrome P450	Endocrinology
YM511 is a highly specific non-steroidal aromatase inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones .

HY-113313

Aldosterone 5+ Cited Publications	Endogenous Metabolite	Cardiovascular Disease
Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .

HY-B0141

Estradiol Maximum Cited Publications 87 Publications Verification β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol	Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Endocrinology Cancer
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-137178

20α,22R-Dihydroxycholesterol	Endogenous Metabolite	Metabolic Disease
20α,22R-Dihydroxycholesterol is an endogenous metabolic intermediate. 20α,22R-Dihydroxycholesterol involved in the biosynthesis of cholesterol to steroid hormones .

HY-14650R

DHEA (Standard) Prasterone (Standard); Dehydroisoandrosterone (Standard); Dehydroepiandrosterone (Standard)	Androgen Receptor Endogenous Metabolite	Metabolic Disease
DHEA (Prasterone) (Standard) is the analytical standard of DHEA. This product is intended for research and analytical applications. DHEA is a steroid hormone .

HY-P3489

β-Corticotropin (swine)	Melanocortin Receptor	Endocrinology
β-Corticotropin (swine) is a synthetic form of the peptide hormone corticotropin (ACTH). β-Corticotropin stimulates steroid release .

HY-N15362

5α-Pregnane-3β,17α,20α-triol	Endogenous Metabolite	Endocrinology
5α-Pregnane-3β,17α,20α-triol is an endogenous steroid compound. 5α-Pregnane-3β,17α,20α-triol is the metabolite of Pregnenolone (HY-B0151) or Progesterone (HY-N0437). 5α-Pregnane-3β,17α,20α-triol is promising for research of the endocrine function of the placenta and the mechanisms related to steroid hormone metabolism during pregnancy .

HY-N15363

5-Pregnene-3β,17a,20a-triol	Endogenous Metabolite	Metabolic Disease Endocrinology
5-Pregnene-3β,17a,20a-triol is an endogenous steroid compound. 5-Pregnene-3β,17a,20a-triol plays a role in maintaining the body's hormonal balance. 5-Pregnene-3β,17a,20a-triol is promising for research of congenital steroid synthesis enzyme deficiency diseases .

HY-NP186

Helix pomatia Agglutinin	Biochemical Assay Reagents	Cancer
Helix pomatia Agglutinin is a N-acetylgalactosamine (GalNAc) binding lectin, found in the reproductive gland of a Roman snail. Helix pomatia Agglutinin binds with high affinity (k_D = 1.9-2.4 μM) steroid hormones: testosterone and progesterone. Helix pomatia Agglutinin interacts with adenine (k_D = 5.4 μM) and arylaminonaphthalene sulfonate TNS (k_D = 12 μM). Helix pomatia Agglutinin is commonly used for characterizing, imaging, or targeting glycoconjugates, and is also a very useful tool for glycomics analysis . Helix pomatia Agglutinin can be used for cancer prognosis study .

HY-B0141C

Estradiol hemihydrate β-Estradiol hemihydrate; 17β-Estradiol hemihydrate; 17β-Oestradiol hemihydrate	Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Neurological Disease Cancer
Estradiol (β-Estradiol) hemihydrate is a steroid hormone and the major female sex hormone. Estradiol (β-Estradiol) hemihydrate can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (β-Estradiol) hemihydrate can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-17462

Adrenosterone (+)-Adrenosterone	Androgen Receptor Endogenous Metabolite	Endocrinology Cancer
Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor. Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells .

HY-N0179

Ecdysone 1 Publications Verification α-Ecdysone	Endogenous Metabolite Apoptosis	Metabolic Disease
Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979) .

HY-164357

14-Deoxypoststerone	Others	Metabolic Disease
14-Deoxypoststerone is a steroid compound, a derivative of a steroid hormone .

HY-N0437

Progesterone 25+ Cited Publications Pregn-4-ene-3,20-dione	Progesterone Receptor Endogenous Metabolite	Cardiovascular Disease Cancer
Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-N0583

Hydrocortisone 45+ Cited Publications Cortisol	Glucocorticoid Receptor Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-B0672

Estradiol valerate β-Estradiol 17-valerate	Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerate (β-Estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-150542

Steroid sulfatase-IN-2	Steroid Sulfatase	Cancer
Steroid sulfatase -IN-2 is an active steroid sulfatase (STS) inhibitor with an IC₅₀ value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrial cancer .

HY-P2110

RS-18286	GnRH Receptor	Endocrinology
RS-18286 is a potent *luteinizing-hormone* (LH)-releasing hormone (LHRH)** antagonist. RS-18286 blocks the pituitary LHRH receptor and suppresses pituitary luteinizing-hormone (LH) secretion and reduce serum concentrations of gonadal steroids .

HY-N0437S

Progesterone-d9 Pregn-4-ene-3,20-dione-d₉	Progesterone Receptor Endogenous Metabolite	Cardiovascular Disease Cancer
Progesterone-d₉ is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-N0583S1

Hydrocortisone-d7 Cortisol-d₇	Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology Cancer
Hydrocortisone-d₇ is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-N0583S3

Hydrocortisone-d3 Cortisol-d₃	Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology Cancer
Hydrocortisone-d₃ is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-N0583S2

Hydrocortisone-d4 Cortisol-d₄	Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology Cancer
Hydrocortisone-d₄ is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-77839S1

Cortodoxone-d2 11-Deoxycortisol-d₂; cortexolone-d₂; Reichstein's substance S-d₂	Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Cortodoxone-d₂ is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone) .

HY-N0437S2

Progesterone-13C3	Isotope-Labeled Compounds Progesterone Receptor Endogenous Metabolite	Cardiovascular Disease Cancer
Progesterone- ¹³C₃ is the ¹³C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-W751098

Aldosterone-13C3	Isotope-Labeled Compounds	Others
Aldosterone- ¹³C₃ is a ¹³C-labeled Aldosterone (HY-113313). Aldosterone is a primary mineralocorticoid and steroid hormone.

HY-N0583S5

Hydrocortisone-d2 Cortisol-d₂	Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology
Hydrocortisone-d₂ is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-N0437S1

Progesterone-13C5 Pregn-4-ene-3,20-dione-¹³C₅	Isotope-Labeled Compounds Progesterone Receptor Endogenous Metabolite	Cardiovascular Disease Cancer
Progesterone- ¹³C₅ is the ¹³C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-N0437S3

Progesterone-13C2 Pregn-4-ene-3,20-dione-¹³C₂	Isotope-Labeled Compounds Progesterone Receptor Endogenous Metabolite	Cardiovascular Disease Cancer
Progesterone- ¹³C₂ is the ¹³C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-W701984

11β-Hydroxyetiocholanolone	Glucocorticoid Receptor	Endocrinology
11β-Hydroxyetiocholanolone is a metabolite of Hydrocortisone (HY-N0583). Hydrocortisone is a steroid hormone or glucocorticoid secreted by the adrenal cortex.

HY-B0672S1

Estradiol valerianate-d4 β-Estradiol 17-valerate-d₄	Isotope-Labeled Compounds Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerianate-d₄ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-B0672S

Estradiol valerianate-d9	Isotope-Labeled Compounds Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerianate-d₉ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-107630

RU 26752	Mineralocorticoid Receptor	Cardiovascular Disease
RU 26752 is a steroid hormone receptor antagonist. RU 26752 can prevent hypertension caused by aldosterone (HY-113313) in rats .

HY-N0437R

Progesterone (Standard) 25+ Cited Publications Pregn-4-ene-3,20-dione (Standard)	Progesterone Receptor Endogenous Metabolite	Cardiovascular Disease Cancer
Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-B0216

Ethinylestradiol 3 Publications Verification Ethynyl estradiol; 17α-Ethynylestradiol	Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers .

HY-N0583R

Hydrocortisone (Standard) 45+ Cited Publications Cortisol (Standard)	Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology Cancer
Hydrocortisone (Standard) is the analytical standard of Hydrocortisone. This product is intended for research and analytical applications. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-N8550

Cortolone α-Cortolone	Glucocorticoid Receptor	Endocrinology
Cortolone (α-Cortolone) is a metabolite of the glucocorticoid cortisol (Hydrocortisone (HY-N0583)). Hydrocortisone is a steroid hormone or glucocorticoid secreted by the adrenal cortex.

HY-B0672R

Estradiol valerate (Standard) β-Estradiol 17-valerate (Standard)	Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerianate (Standard) is the analytical standard of Estradiol valerianate. This product is intended for research and analytical applications. Estradiol valerate (β-Estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-I0352

Epiandrosterone 3β-Androsterone; trans-Androsterone; iso-Androsterone	Endogenous Metabolite Potassium Channel	Metabolic Disease Endocrinology
Epiandrosterone is a steroid hormone. Epiandrosterone activates BKCa. Epiandrosterone inhibits glucose transport and insulin release. Epiandrosterone has weak androgenic activity .

HY-P3673

Lamprey LH-RH I	GnRH Receptor	Endocrinology
Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models .

HY-113414S

Deoxycorticosterone-d8	Endogenous Metabolite	Others
Deoxycorticosterone-d₈ is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor .

HY-113263

17a-Hydroxypregnenolone 2 Publications Verification	Endogenous Metabolite	Endocrinology
17a-Hydroxypregnenolone is an intermediate in the synthesis of steroid hormones and may be related to the synthesis of sex hormones or adrenal hormones. The sulfate form of 17a-Hydroxypregnenolone (17α-hydroxypregnenolone sulfate) is the main interfering substance in neonatal plasma, which can significantly affect the immunoassay results of 17α-hydroxyprogesterone (17-OHP) by cross-reacting with antibodies .

HY-113414R

Deoxycorticosterone (Standard)	Endogenous Metabolite	Others
Deoxycorticosterone (Standard) is the analytical standard of Deoxycorticosterone. This product is intended for research and analytical applications. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor.

HY-E70508

Human CYP17A1,Low-Reductase	Cytochrome P450	Metabolic Disease
Human CYP17A1, Low-Reductase, a recombinant CYP17A1, is a member of the CYP enzyme family. CYP17A1 plays a crucial role in human steroid hormone synthesis .

HY-14383

Vosilasarm 5+ Cited Publications RAD140; EP0062	Androgen Receptor	Neurological Disease Endocrinology Cancer
Vosilasarm (RAD140) is a potent, orally active, nonsteroidal selective androgen receptor modulator (SARM) with a K_i of 7 nM. Vosilasarm shows good selectivity over other steroid hormone nuclear receptors .

HY-113313S2

Aldosterone-d4	Endogenous Metabolite	Cardiovascular Disease
Aldosterone-d₄ is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by t

HY-125787

MLS000389544	Thyroid Hormone Receptor	Metabolic Disease
MLS000389544 is a selective and potent methylsulfonylnitrobenzoate thyroid hormone receptor β (TRβ) antagonist that blocks the association of TRβ with steroid receptor coactivator 2 (SRC2) .

HY-E70509

Human CYP17A1,High-Reductase	Cytochrome P450	Metabolic Disease
Human CYP17A1, High-Reductase, a recombinant CYP17A1, is a member of the CYP enzyme family. CYP17A1 plays a crucial role in human steroid hormone synthesis .

HY-118541

RH-5849	Insecticide	Others
RH-5849 is an orally active agonist for *non-steroidal* ecdysteroid*, which inhibits the larval growth of Plodia inferpuncteila* in a dose-dependent manner. RH-5849 exhibits molting hormone activity .

HY-77839

Cortodoxone 3 Publications Verification 11-Deoxycortisol; cortexolone; Reichstein's substance S	Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .

HY-E70512

Human CYP17A1,High-Reductase+b5	Cytochrome P450	Metabolic Disease
Human CYP17A1, High-Reductase+b5, a recombinant CYP17A1, is a member of the CYP enzyme family. CYP17A1 plays a crucial role in human steroid hormone synthesis .

Cat. No.	Product Name	Type

HY-NP186

Helix pomatia Agglutinin

Native Proteins

Helix pomatia Agglutinin is a N-acetylgalactosamine (GalNAc) binding lectin, found in the reproductive gland of a Roman snail. Helix pomatia Agglutinin binds with high affinity (k_D = 1.9-2.4 μM) steroid hormones: testosterone and progesterone. Helix pomatia Agglutinin interacts with adenine (k_D = 5.4 μM) and arylaminonaphthalene sulfonate TNS (k_D = 12 μM). Helix pomatia Agglutinin is commonly used for characterizing, imaging, or targeting glycoconjugates, and is also a very useful tool for glycomics analysis . Helix pomatia Agglutinin can be used for cancer prognosis study .

Cat. No.	Product Name	Target	Research Area

HY-P0097A

Nonapeptide-1 acetate salt 2 Publications Verification Melanostatine-5 acetate salt	Melanocortin Receptor	Metabolic Disease Endocrinology Cancer
Nonapeptide-1 (Melanostatine-5) acetate salt, a peptide hormone, is a selective antagonist of MC1R (K_i: 40 nM). Nonapeptide-1 acetate salt is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC₅₀: 2.5 nM and 11 nM, respectively). Nonapeptide-1 acetate salt inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .

HY-P0097

Nonapeptide-1 2 Publications Verification Melanostatine-5	Melanocortin Receptor	Metabolic Disease Endocrinology Cancer
Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (K_i: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC₅₀: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .

HY-P3489

β-Corticotropin (swine)	Melanocortin Receptor	Endocrinology
β-Corticotropin (swine) is a synthetic form of the peptide hormone corticotropin (ACTH). β-Corticotropin stimulates steroid release .

HY-P2110

RS-18286	GnRH Receptor	Endocrinology
RS-18286 is a potent *luteinizing-hormone* (LH)-releasing hormone (LHRH)** antagonist. RS-18286 blocks the pituitary LHRH receptor and suppresses pituitary luteinizing-hormone (LH) secretion and reduce serum concentrations of gonadal steroids .

HY-P3673

Lamprey LH-RH I	GnRH Receptor	Endocrinology
Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113313

Aldosterone 5+ Cited Publications	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .

HY-B0141

Estradiol Maximum Cited Publications 87 Publications Verification β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol	Structural Classification Classification of Application Fields Source classification Endocrine diseases Endogenous metabolite Monophenols Sunscreen Disease markers Phenols Cosmetic Research Disease Research Fields Steroids Cancer	Estrogen Receptor/ERR Endogenous Metabolite Bacterial
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-17462

Adrenosterone (+)-Adrenosterone	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Androgen Receptor Endogenous Metabolite
Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor. Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells .

HY-N0179

Ecdysone 1 Publications Verification α-Ecdysone	Structural Classification Animals Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite Apoptosis
Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979) .

HY-N0437

Progesterone 25+ Cited Publications Pregn-4-ene-3,20-dione	Structural Classification Microorganisms Other disease Classification of Application Fields Source classification Disease markers Endogenous metabolite Disease Research Fields Cancer	Progesterone Receptor Endogenous Metabolite
Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-N0583

Hydrocortisone 45+ Cited Publications Cortisol	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids Cancer	Glucocorticoid Receptor Endogenous Metabolite
Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-137178

20α,22R-Dihydroxycholesterol	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
20α,22R-Dihydroxycholesterol is an endogenous metabolic intermediate. 20α,22R-Dihydroxycholesterol involved in the biosynthesis of cholesterol to steroid hormones .

HY-14650R

DHEA (Standard) Prasterone (Standard); Dehydroisoandrosterone (Standard); Dehydroepiandrosterone (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	Androgen Receptor Endogenous Metabolite
DHEA (Prasterone) (Standard) is the analytical standard of DHEA. This product is intended for research and analytical applications. DHEA is a steroid hormone .

HY-N15362

5α-Pregnane-3β,17α,20α-triol	Structural Classification Animals Source classification Steroids	Endogenous Metabolite
5α-Pregnane-3β,17α,20α-triol is an endogenous steroid compound. 5α-Pregnane-3β,17α,20α-triol is the metabolite of Pregnenolone (HY-B0151) or Progesterone (HY-N0437). 5α-Pregnane-3β,17α,20α-triol is promising for research of the endocrine function of the placenta and the mechanisms related to steroid hormone metabolism during pregnancy .

HY-N15363

5-Pregnene-3β,17a,20a-triol	Structural Classification Source classification Endogenous metabolite Steroids	Endogenous Metabolite
5-Pregnene-3β,17a,20a-triol is an endogenous steroid compound. 5-Pregnene-3β,17a,20a-triol plays a role in maintaining the body's hormonal balance. 5-Pregnene-3β,17a,20a-triol is promising for research of congenital steroid synthesis enzyme deficiency diseases .

HY-N0437R

Progesterone (Standard) 25+ Cited Publications Pregn-4-ene-3,20-dione (Standard)	Structural Classification Other disease Classification of Application Fields Source classification Disease markers Endogenous metabolite Disease Research Fields Steroids Cancer	Progesterone Receptor Endogenous Metabolite
Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-B0216

Ethinylestradiol 3 Publications Verification Ethynyl estradiol; 17α-Ethynylestradiol	Structural Classification Monophenols Classification of Application Fields Source classification Phenols Endogenous metabolite Disease Research Fields Steroids Cancer	Estrogen Receptor/ERR Endogenous Metabolite
Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers .

HY-N0583R

Hydrocortisone (Standard) 45+ Cited Publications Cortisol (Standard)	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids Cancer	Glucocorticoid Receptor Endogenous Metabolite
Hydrocortisone (Standard) is the analytical standard of Hydrocortisone. This product is intended for research and analytical applications. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-N8550

Cortolone α-Cortolone	Structural Classification Natural Products Source classification Endogenous metabolite	Glucocorticoid Receptor
Cortolone (α-Cortolone) is a metabolite of the glucocorticoid cortisol (Hydrocortisone (HY-N0583)). Hydrocortisone is a steroid hormone or glucocorticoid secreted by the adrenal cortex.

HY-I0352

Epiandrosterone 3β-Androsterone; trans-Androsterone; iso-Androsterone	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite Potassium Channel
Epiandrosterone is a steroid hormone. Epiandrosterone activates BKCa. Epiandrosterone inhibits glucose transport and insulin release. Epiandrosterone has weak androgenic activity .

HY-113263

17a-Hydroxypregnenolone 2 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Classification of Application Fields Source classification Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
17a-Hydroxypregnenolone is an intermediate in the synthesis of steroid hormones and may be related to the synthesis of sex hormones or adrenal hormones. The sulfate form of 17a-Hydroxypregnenolone (17α-hydroxypregnenolone sulfate) is the main interfering substance in neonatal plasma, which can significantly affect the immunoassay results of 17α-hydroxyprogesterone (17-OHP) by cross-reacting with antibodies .

HY-113414R

Deoxycorticosterone (Standard)	Structural Classification Classification of Application Fields Source classification Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Deoxycorticosterone (Standard) is the analytical standard of Deoxycorticosterone. This product is intended for research and analytical applications. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor.

HY-77839

Cortodoxone 3 Publications Verification 11-Deoxycortisol; cortexolone; Reichstein's substance S	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Glucocorticoid Receptor Endogenous Metabolite
Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .

HY-B0141R

Estradiol (Standard) Maximum Cited Publications 87 Publications Verification β-Estradiol(Standard); E2(Standard); 17β-Estradiol(Standard); 17β-Oestradiol (Standard)	Structural Classification Classification of Application Fields Sunscreen Source classification Disease markers Phenols Endocrine diseases Cosmetic Research Endogenous metabolite Disease Research Fields Steroids Cancer	Estrogen Receptor/ERR Endogenous Metabolite Bacterial
Estradiol (Standard) is the analytical standard of Estradiol. This product is intended for research and analytical applications. Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-113414

Deoxycorticosterone 4 Publications Verification	Structural Classification Classification of Application Fields Source classification Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite Mineralocorticoid Receptor
Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor (rtMR) transcription with EC₅₀ of 0.16 nM . Deoxycorticosterone could acts as an immune stimulator in fish .

HY-B0891

17α-Hydroxyprogesterone 4 Publications Verification 17-Hydroxyprogesterone; 17-OHP	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Steroids	Progesterone Receptor Endogenous Metabolite
17α-Hydroxyprogesterone is a steroid hormone. 17α-Hydroxyprogesterone induces ovarian growth and yolk production in female crabs and increases blood pressure in sheep. 17α-Hydroxyprogesterone is mainly used in research related to crustacean reproduction and animal hypertension .

HY-77839R

Cortodoxone (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	Glucocorticoid Receptor Endogenous Metabolite
Cortodoxone (Standard) is the analytical standard of Cortodoxone. This product is intended for research and analytical applications. Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .

HY-B0151

Pregnenolone 4 Publications Verification 3β-Hydroxy-5-pregnen-20-one	Structural Classification Microorganisms Neurological Disease Classification of Application Fields Anti-aging Source classification Endogenous metabolite Disease Research Fields Steroids	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-B1739

Pregnenolone monosulfate 4 Publications Verification 3β-Hydroxy-5-pregnen-20-one monosulfate	Structural Classification Source classification Endogenous metabolite Steroids	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate can protect the brain from cannabis intoxication . Pregnenolone monosulfate is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-110189

Pregnenolone monosulfate sodium 4 Publications Verification 3β-Hydroxy-5-pregnen-20-one monosulfate sodium	Structural Classification Source classification Endogenous metabolite Steroids	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-113313R

Aldosterone (Standard)	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Aldosterone (Standard) is the analytical standard of Aldosterone. This product is intended for research and analytical applications. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .

HY-141728

Bis(1-chloro-2-propyl) phosphate BCIPP	Structural Classification Natural Products Source classification Disease markers Endogenous metabolite	Endogenous Metabolite
Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

HY-14650

DHEA 30+ Cited Publications Prasterone; Dehydroisoandrosterone; Dehydroepiandrosterone	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Androgen Receptor Endogenous Metabolite
DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.

HY-B0151R

Pregnenolone (Standard) 4 Publications Verification 3β-Hydroxy-5-pregnen-20-one (Standard)	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Endogenous metabolite Disease Research Fields Steroids	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
Pregnenolone (Standard) is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

Cat. No.	Product Name	Chemical Structure

HY-N0437S

Progesterone-d9
Progesterone-d₉ is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-N0583S1

Hydrocortisone-d7
Hydrocortisone-d₇ is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-N0583S3

Hydrocortisone-d3
Hydrocortisone-d₃ is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-N0583S2

Hydrocortisone-d4
Hydrocortisone-d₄ is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-77839S1

Cortodoxone-d2
Cortodoxone-d₂ is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone) .

HY-N0437S2

Progesterone-13C3
Progesterone- ¹³C₃ is the ¹³C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-N0437S3

Progesterone-13C2
Progesterone- ¹³C₂ is the ¹³C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-W751098

Aldosterone-13C3
Aldosterone- ¹³C₃ is a ¹³C-labeled Aldosterone (HY-113313). Aldosterone is a primary mineralocorticoid and steroid hormone.

HY-N0583S5

Hydrocortisone-d2
Hydrocortisone-d₂ is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .

HY-N0437S1

Progesterone-13C5
Progesterone- ¹³C₅ is the ¹³C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-B0672S1

Estradiol valerianate-d4
Estradiol valerianate-d₄ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-B0672S

Estradiol valerianate-d9
Estradiol valerianate-d₉ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-113414S

Deoxycorticosterone-d8
Deoxycorticosterone-d₈ is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor .

HY-113313S2

Aldosterone-d4
Aldosterone-d₄ is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by t

HY-B0141S

Estradiol-d3
Estradiol-d₃ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.

HY-B0891S

17α-Hydroxyprogesterone-d8
17α-Hydroxyprogesterone-d₈ is the deuterium labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-B0141S2

Estradiol-d5
Estradiol-d₅ is deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .

HY-B0141S3

Estradiol-d2
Estradiol-d₂ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .

HY-B0141S1

Estradiol-d4 1 Publications Verification
Estradiol-d₄ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .

HY-B1192S

Estradiol benzoate-d3
Estradiol benzoate-d₃ is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a proagent of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability .

HY-B0891S1

17α-Hydroxyprogesterone-13C3
17α-Hydroxyprogesterone- ¹³C₃ is the ¹³C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-B0141S6

Estradiol-d2-1
Estradiol-d₂-1 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .

HY-B0141S4

Estradiol-13C6
Estradiol- ¹³C₆ is the ¹³C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .

HY-B0141S5

Estradiol-13C2
Estradiol- ¹³C₂ is the ¹³C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .

HY-13632S

Exemestane-d2
Exemestane-d₂ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S2

Exemestane-d3
Exemestane-d₃ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S1

Exemestane-13C3
Exemestane- ¹³C₃ is the ¹³C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-W653985

Cortodoxone-d7
Cortodoxone-d₇ (11-Deoxycortisol-d₇) is a deuterium labeled Cortodoxone (HY-77839). Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .

HY-113313S1

Aldosterone-d7

Aldosterone-d₇ is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .

HY-B0151S1

Pregnenolone-13C2,d2

Pregnenolone- ¹³C₂,d₂ is the deuterium and ¹³C labeled Pregnenolone (HY-B0151). Pregnenolone is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-B0151S

Pregnenolone-d4

Pregnenolone-d₄ is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-B0151S2

Pregnenolone-d4-1

Pregnenolone-d₄-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-13632S6

Exemestane-d4
Exemestane-d₄ (FCE 24304-d₄) is deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S5

Exemestane-13C,d2
Exemestane- ¹³C,d₂ is ¹³C and deuterated labeled Exemestane (HY-13632). Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-110189S1

Pregnenolone monosulfate-d4 sodium

Pregnenolone monosulfate-d₄ (sodium) is the deuterium labeled Pregnenolone monosulfate. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-110189S

Pregnenolone monosulfate sodium-13C2,d2

Pregnenolone monosulfate (sodium)- ¹³C₂,d₂ is the ¹³C- and deuterium labeled Pregnenolone monosulfate sodium. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication . Pregnenolone monosulfate sodium salt is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-W653929

Bis(1-chloro-2-propyl) phosphate-d12

Bis(1-chloro-2-propyl) phosphate-d₁₂ is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

Cat. No.	Product Name		Classification

HY-B0216

Ethinylestradiol 3 Publications Verification Ethynyl estradiol; 17α-Ethynylestradiol		Alkynes
Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers .

HY-101405

Gestrinone R 2323		Alkynes
Gestrinone (R2323) is a synthetic steroid hormone used to treat endometriosis. It inhibits leiomyoma cells with an IC₅₀ of 43.67 μM. Gestrinone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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