2. Metabolic Enzyme/Protease
  3. Steroid Sulfatase
  4. KW-2581

KW-2581 is a steroidal selective steroid sulfatase inhibitor with an IC50 of 4 nM. KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells both in vitro and in vivo. KW-2581 induced regression in E1S-induced tumor growth. KW-2581 can be studied in research on hormone receptors-positive breast cancer.

For research use only. We do not sell to patients.

KW-2581

KW-2581 Chemical Structure

CAS No. : 284045-56-3

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Description

KW-2581 is a steroidal selective steroid sulfatase inhibitor with an IC50 of 4 nM. KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells both in vitro and in vivo. KW-2581 induced regression in E1S-induced tumor growth. KW-2581 can be studied in research on hormone receptors-positive breast cancer[1].

Molecular Weight

460.63

Formula

C25H36N2O4S
CAS No.
SMILES

O=S(OC1=CC=C2[C@@]3([H])CC[C@]4(C)C(C(N(C(C)C)C(C)C)=O)=CC[C@@]4([H])[C@]3([H])CCC2=C1)(N)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KW-2581 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KW-2581284045-56-3KW2581KW 2581Steroid SulfataseInhibitorinhibitorinhibit

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