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Results for "

peptide engineering

" in MedChemExpress (MCE) Product Catalog:

By Targets:	RXFP Receptor (1) Amino Acid Derivatives (1) Biochemical Assay Reagents (4) CaMK (1) VEGFR (1)
By Research Areas:	Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Targets Recommended: Formyl Peptide Receptor (FPR) Connective Peptide Peptide-Drug Conjugates (PDCs) Natriuretic Peptide Receptor (NPR) RXFP Receptor CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W009033

Cbz-Lys(Boc)-OH	Biochemical Assay Reagents Amino Acid Derivatives	Others
Cbz-Lys(Boc)-OH is a protected amino acid, primarily utilized in peptide synthesis, protein engineering, and drug development, particularly in research involving lysine residues .

HY-W835525

N-(Biotinoyl)-N''-(iodoacetyl)ethylenediamine	Biochemical Assay Reagents	Others
N-(Biotinoyl)-N''-(iodoacetyl)ethylenediamine is a biotinylated biochemical assay reagent that forms a layer of biotin derivative on the surface of ORMOCER, and triggers the assembly of peptide nanostructured fibers. N-(Biotinoyl)-N''-(iodoacetyl)ethylenediamine can be used for 3D assembly of peptides in molecular electronics, biosensors, and tissue engineering .

HY-P5558

KLTWQELYQLKYKGI	VEGFR	Neurological Disease
KLTWQELYQLKYKGI is a VEGF mimetic peptide designed based on the VEGF helix sequence 17-25, with the ability to activate VEGF receptors and exert pro-angiogenic biological activity. KLTWQELYQLKYKGI effectively promotes the attachment, spreading and proliferation of human umbilical vein endothelial cells. KLTWQELYQLKYKGI enhances the proliferation, migration and osteogenic differentiation of bone marrow stromal cells (BMSCs). KLTWQELYQLKYKGI synergistically accelerates angiogenesis and bone regeneration in rat cranial defect models. KLTWQELYQLKYKGI can be used for the research of brain tissue engineering and traumatic brain injury repair and biomaterials for bone tissue engineering and bone repair .

HY-Y0623

N-Hydroxysuccinimide 3 Publications Verification HOSu; 1-Hydroxy-2,5-pyrrolidinedione	Biochemical Assay Reagents	Others
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .

HY-P10499

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302)	CaMK	Others
[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors .

HY-164076

mPEG-Epoxide	Biochemical Assay Reagents	Others
mPEG-Epoxide is an activated polyethylene glycol (mPEG) derivative, which is achieved by converting the hydroxyl groups of mPEG into reactive epoxy groups. mPEG-Epoxide is a mild PEGylation reagent that reacts with amino groups in peptides and proteins to form stable secondary amine bonds. mPEG-Epoxide can be used in protein engineering and biomaterials research .

HY-P11246

A13:B7-24-GG	RXFP Receptor	Metabolic Disease
A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a K_i value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (K_i = 602.56 nM) and an inhibitory effect on cAMP (EC₅₀) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC₅₀ of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .

Cat. No.	Product Name	Type

HY-W835525

N-(Biotinoyl)-N''-(iodoacetyl)ethylenediamine	Biochemical Assay Reagents
N-(Biotinoyl)-N''-(iodoacetyl)ethylenediamine is a biotinylated biochemical assay reagent that forms a layer of biotin derivative on the surface of ORMOCER, and triggers the assembly of peptide nanostructured fibers. N-(Biotinoyl)-N''-(iodoacetyl)ethylenediamine can be used for 3D assembly of peptides in molecular electronics, biosensors, and tissue engineering .

HY-Y0623

N-Hydroxysuccinimide 3 Publications Verification HOSu; 1-Hydroxy-2,5-pyrrolidinedione	Biochemical Assay Reagents
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .

N-Hydroxysuccinimide

3 Publications Verification

HOSu; 1-Hydroxy-2,5-pyrrolidinedione

Biochemical Assay Reagents

N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .

Cat. No.	Product Name	Target	Research Area

HY-P5558

KLTWQELYQLKYKGI	VEGFR	Neurological Disease
KLTWQELYQLKYKGI is a VEGF mimetic peptide designed based on the VEGF helix sequence 17-25, with the ability to activate VEGF receptors and exert pro-angiogenic biological activity. KLTWQELYQLKYKGI effectively promotes the attachment, spreading and proliferation of human umbilical vein endothelial cells. KLTWQELYQLKYKGI enhances the proliferation, migration and osteogenic differentiation of bone marrow stromal cells (BMSCs). KLTWQELYQLKYKGI synergistically accelerates angiogenesis and bone regeneration in rat cranial defect models. KLTWQELYQLKYKGI can be used for the research of brain tissue engineering and traumatic brain injury repair and biomaterials for bone tissue engineering and bone repair .

HY-P5284

RALA peptide	Peptides	Others
RALA peptide is a cationic amphiphilic delivery agent targeting cell membranes, which forms nanoparticles through electrostatic interactions with anionic drugs. RALA peptide has pH-responsive binding properties, which can enhance the α-helical conformation in an acidic environment and destroy the endosomal membrane, promote the release of drugs into the cytoplasm, and exert efficient intracellular delivery activity. RALA peptide can be used in cancer research (enhancing the activity of bisphosphonates against prostate cancer and breast cancer cells) and bone tissue engineering (promoting osteoblast collagen deposition and extracellular matrix mineralization) .

HY-P2263

KLD-12	Peptides	Inflammation/Immunology
KLD-12 is a 12-residue self-assembling peptide that is used in tissue-engineering. KLD-12 combined with SDF-1 self-assembled polypeptide enhances chondrogenic differentiation of bone marrow stromal cells (BMSCs). KLD-12 hydrogel can fill full-thickness osteochondral defects in situ and improve cartilage repair .

HY-P2263A

KLD-12 TFA	Peptides	Inflammation/Immunology
KLD-12 TFA is the TFA salt form of KLD-12 (HY-P2263). KLD-12 TFA is a self a 12-residue self-assembling peptide that is used in tissue-engineering. KLD-12 TFA combined with SDF-1 self-assembled polypeptide enhances chondrogenic differentiation of bone marrow stromal cells (BMSCs). KLD-12 TFA hydrogel can fill full-thickness osteochondral defects in situ and improve cartilage repair .

HY-P4054

IEIK 13	Peptides	Others
IEIK 13 is a self-assembling peptide (SAP) sequence. IEIK 13 can be used for the research of cartilage tissue engineering

HY-P10499

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302)	CaMK	Others
[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors .

HY-P5350

FN-A208 fusion peptide	Peptides	Others
FN-A208 is a biological active peptide. (This peptide is a fusion of A208, derived from murine laminin a1, and the active site of fibronectin (GRGDS), with a glycine spacer. This peptide forms amyloid-like fibrils and promotes formation of actin stress fibers that mediate fibroblast cell attachment, offering it potential as a bioadhesive for tissue regeneration and engineering. FN-A208 interacts with IKVAV receptors and integrins. Its activity is disrupted by the presence of EDTA.)

HY-P10999

INF7TAT-P55 P55	Peptides	Others
INF7TAT-P55 (P55) is a peptide that enables ribonucleoprotein delivery for CRISPR engineering. INF7TAT-P55 supports efficient genome editing in T cells with excellent yields, and is well suited for CD34+ HSPCs .

HY-P11246

A13:B7-24-GG	RXFP Receptor	Metabolic Disease
A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a K_i value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (K_i = 602.56 nM) and an inhibitory effect on cAMP (EC₅₀) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC₅₀ of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .

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