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Isoforms Recommended: Lck
Results for "

p56Lck

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

2

Natural
Products

1

Recombinant Proteins

5

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108485
    Damnacanthal

    		Src Apoptosis Fungal Infection Inflammation/Immunology Cancer
    Damnacanthal is an anthraquinone isolated from the root of Morinda citrifolia. Damnacanthal is a highly potent, selective inhibitor of p56 lck tyrosine kinase activity. Natural Damnacanthal inhibits p56 lck autophosphorylation and phosphorylation of exogenous substrates with IC50s of 46 nM and 220 nM, respectively. Damnacanthal is a potent inducer of apoptosis with anticancer activity. Damnacanthal also has antinociceptive, anti-inflammatory effects in mice and anti-fungal activity against Candida albicans .
    Damnacanthal
  • HY-112291
    SB 220025

    		p38 MAPK Src PKC Inflammation/Immunology
    SB 220025 is a reversible, orally active, cell-permeable, ATP-competitive and selective human p38 MAPK inhibitor (IC50 = 60 nM). SB 220025 also inhibits p56 Lck and PKC with IC50 values of 3.5 and 2.89 µM, respectively. SB 220025 inhibits the expression of IL-8 gene in response to globular adiponectin (gAd), reduces inflammatory cytokine production and inhibits angiogenesis. SB 220025 effectively prevents the progression of arthritis in a chronic inflammatory disease model and can be used in the study of inflammation .
    SB 220025
  • HY-114980
    BMS-279700

    		Src Interleukin Related TNF Receptor Inflammation/Immunology
    BMS-279700 is an orally active Src-family kinase p56Lck inhibitor. BMS-279700 can block the production of proinflammatory cytokines (IL-2 and TNFα). BMS-279700 can inhibit T cell proliferation. BMS-279700 can be used for the researches of inflammation and immunology .
    BMS-279700
  • HY-120622
    BMS-243117

    		Src Cancer
    BMS-243117 is a potent, and selective benzothiazole based p56 Lck inhibitor with an IC50 of 4 nM. BMS-243117 inhibits anti-CD3/anti-CD28 induced PBL (human peripheral blood T-cells) proliferation with an IC50 of 1.1 μM. BMS-243117 binds in an extended conformation to the ATP-binding site of Lck .
    BMS-243117
  • HY-112291A
    SB 220025 (tri(hydrochloride))

    		p38 MAPK Src PKC Inflammation/Immunology
    SB 220025 trihydrochloride is a reversible, orally active, cell-permeable, ATP-competitive and selective human p38 MAPK inhibitor (IC50 = 60 nM). SB 220025 trihydrochloride also inhibits p56 Lck and PKC with IC50 values of 3.5 and 2.89 μM, respectively. SB 220025 trihydrochloride inhibits the expression of IL-8 gene in response to globular adiponectin (gAd), reduces inflammatory cytokine production and inhibits angiogenesis. SB 220025 trihydrochloride effectively prevents the progression of arthritis in a chronic inflammatory disease model and can be used in the study of inflammation .
    SB 220025 (tri(hydrochloride))
  • HY-N12166
    2,3,4,6,8-Pentahydroxy-1-methylxanthone

    		Src Cardiovascular Disease
    2,3,4,6,8-Pentahydroxy-1-methylxanthone is a xanthone derivative of Wardomyces anomalus. 2,3,4,6,8-Pentahydroxy-1-methylxanthone shows significant antioxidant activities. 2,3,4,6,8-Pentahydroxy-1-methylxanthone is inhibitors of p56 lck tyrosine kinase. 2,3,4,6,8-Pentahydroxy-1-methylxanthone can be used to treat cardiovascular disease .
    2,3,4,6,8-Pentahydroxy-1-methylxanthone
  • HY-RS23012
    Lck Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Lck Rat Pre-designed siRNA Set A contains three designed siRNAs for Lck gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Lck Rat Pre-designed siRNA Set A
    Lck Rat Pre-designed siRNA Set A
  • HY-RS07550
    LCK Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    LCK Human Pre-designed siRNA Set A contains three designed siRNAs for LCK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    LCK Human Pre-designed siRNA Set A
    LCK Human Pre-designed siRNA Set A
  • HY-RS16578
    Lck Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Lck Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lck gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Lck Mouse Pre-designed siRNA Set A
    Lck Mouse Pre-designed siRNA Set A

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