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mRNA vaccine

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78

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30

Fluorescent Dye

30

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1

Inhibitory Antibodies

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Click Chemistry

36

Oligonucleotides

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145969A
    β-S-ARCA triammonium

    		DNA/RNA Synthesis Cancer
    β-S-ARCA (triammonium) is a mRNA 7-methylguanosine (m 7G) cap analog carrying a phosphorothioate (PS) moiety. mRNA incorporating β-S-ARCA (triammonium) can prolong cellular half-life and increase protein expression. β-S-ARCA (triammonium) can be used in research of mRNA-based anti-cancer vaccines .
    β-S-ARCA triammonium
  • HY-134541
    SM-102
    Maximum Cited Publications
    26 Publications Verification

    		 Liposome Infection
    SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102
  • HY-153879
    C12-TLRa

    		Liposome Toll-like Receptor (TLR) Infection Inflammation/Immunology
    C12-TLRa is an ionized adjuvant lipid. C12-TLRa targets TLR7/8 receptors in endosomes. C12-TLRa enhances mRNA delivery as a structural component of LNPs. C12-TLRa enhances innate immune responses. C12-TLRa can be used for the research of SARS-CoV-2 mRNA vaccine .
    C12-TLRa
  • HY-151512
    A12-Iso5-4DC19

    		Liposome Inflammation/Immunology Cancer
    A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .
    A12-Iso5-4DC19
  • HY-134541A
    SM-102 (Excipient, GMP Like)

    		Liposome Infection
    SM-102 (Excipient, GMP Like) is the GMP Like class SM-102 (HY-134541), and can be used as pharmaceutical excipients. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 (Excipient, GMP Like) has higher transfection efficiency. SM-102 (Excipient, GMP Like) plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102 (Excipient, GMP Like)
  • HY-171927
    Lipid 12T-O14

    		Liposome Inflammation/Immunology Cancer
    Lipid 12T-O14 is a lipid nanoparticle. 12T-O14 facilitates local mRNA vaccine and systemic mRNA agent delivery .
    Lipid 12T-O14
  • HY-132289
    Lipid M

    		Liposome Inflammation/Immunology
    Lipid M (pKa: 6.75) can be used to deliver mRNA vaccine and yield a robust immune response with improved tolerability .
    Lipid M
  • HY-145969
    β-S-ARCA

    		DNA/RNA Synthesis Others
    β-S-ARCA is a mRNA 7-methylguanosine (m 7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines .
    β-S-ARCA
  • HY-153235
    COVID-19 Spike Protein mRNA-LNP

    		mRNA SARS-CoV Liposome Infection
    COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein. COVID-19 Spike Protein undertakes the functions of virus binding with host cell receptors, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design. COVID-19 Spike Protein mRNA-LNP can be used for RNA delivery, vaccine formulation and design targeting SARS-CoV-2 .
    COVID-19 Spike Protein mRNA-LNP
  • HY-158867
    DOSPA (hydrochlorid)

    		Liposome Infection
    DOSPA hydrochlorid is a frequently utilized cationic lipid in the generation of Lipid Nanoparticles (LNPs) for the development of mRNA vaccines, including the COVID-19 vaccine.
    DOSPA (hydrochlorid)
  • HY-W440931
    MPEG2000-DMG

    		Liposome Cancer
    MPEG2000-DMG is a synthetic lipid comprised of polyPEG and dimyristoyl glycerol. It is used in the creation of lipid nanoparticles (LNPs) for mRNA vaccines.
    MPEG2000-DMG
  • HY-176753
    Lipid 20b

    		Liposome Inflammation/Immunology
    Lipid 20b is a thiophene ionizable cationic lipid. Lipid 20 b can be used to generate lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Lipid 20b can be studied in research for enhancing mRNA vaccine delivery and transfection efficacy .
    Lipid 20b
  • HY-W440906
    DSPE-PEG-Vinylsulfone (MW 3400)

    		Biochemical Assay Reagents Others
    DSPE-PEG-Vinylsulfone, MW 3400 is a thiol reactive PEG lipid. The polymer can self-assemble spontaneously in aqueous solution to form lipid bilayer and be used to prepare nanoparticles/liposomes for drug delivery, for example mRNA vaccine or DNA vaccine. Reagent grade, for research use only.
    DSPE-PEG-Vinylsulfone (MW 3400)
  • HY-138170
    ALC-0315
    20+ Cited Publications

    		 Liposome SARS-CoV Infection
    ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315
  • HY-171898
    Lipid I97

    		Liposome Inflammation/Immunology Cancer
    Lipid I97 is an ionizable lipid derived from vitamin B5 (pKa = 6.23). Lipid I97 can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vivo. Lipid I97 can be studied in research for enhancing mRNA transfection efficiency and long-term stability as well as formulation of mRNA vaccines .
    Lipid I97
  • HY-46759A
    Genevant CL1 monohydrochloride

    		Liposome Infection
    Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .
    Genevant CL1 monohydrochloride
  • HY-W441015A
    DSPE-m-PEG-NHS (MW 3400)

    		Liposome Others
    DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
    DSPE-m-PEG-NHS (MW 3400)
  • HY-46759
    Genevant CL1

    		Liposome Infection
    Genevant CL1 (Lipid 10) is an ionizable lipid (pKa=6.3). Genevant CL1 can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .
    Genevant CL1
  • HY-145795
    OF-02

    		Liposome Others
    OF-02 is an ionizable lipid for mRNA delivery and a key component of lipid nanoparticles (LNPs). OF-02 is protonated in the acidic endosomal environment to promote endosomal escape of mRNA and efficiently induce protein expression in target cells. OF-02 relies on the pH-responsive membrane fusion properties to form a complex with mRNA and destroy the endosomal membrane structure to achieve mRNA release in the cytoplasm. OF-02 is mainly used in the development of mRNA vaccines, gene editing, and protein replacement therapy[1][2][3].
    OF-02
  • HY-150742A
    ODN 2336 sodium

    		Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 2336 sodium is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 sodium induces the production of IFN-α. ODN 2336 sodium up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 sodium can be used as adjuvant of vaccines .
    ODN 2336 sodium
  • HY-150742
    ODN 2336

    		Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 2336 is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 induces the production of IFN-α. ODN 2336 up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 can be used as adjuvant of vaccines .
    ODN 2336
  • HY-148363
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate

    		Liposome Inflammation/Immunology
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate
  • HY-W440895
    DSPE-PEG-SH (MW 1000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-SH (MW 1000) is an amphiphilic poly-PEG that can form lipid bilayers in water. This amphiphilic polymer can form lipid bilayers in aqueous solution and can be used to embed active molecules for drug delivery systems such as mRNA vaccines.
    DSPE-PEG-SH (MW 1000)
  • HY-W440896
    DSPE-PEG-SH, MW 2000

    		Liposome Others
    DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
    DSPE-PEG-SH, MW 2000
  • HY-159700
    AA3-DLin

    		Liposome Infection
    AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
    AA3-DLin
  • HY-145973
    3'OMe-m7GpppAmpG

    m7(3'OMeG)(5')ppp(5')(2'OMeA)pG

    		 DNA/RNA Synthesis Others
    3'OMe-m7GpppAmpG is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG shows a significant translational efficiency. 3'OMe-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .
    3'OMe-m7GpppAmpG
  • HY-138170A
    ALC-0315 (Excipient, GMP Like)

    		Liposome SARS-CoV Infection
    ALC-0315 (Excipient, GMP Like) is the GMP Like class ALC-0315 (HY-138170), and can be used as pharmaceutical excipients. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 (Excipient, GMP Like) can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315 (Excipient, GMP Like)
  • HY-145973A
    3'OMe-m7GpppAmpG (ammonium) solution (100mM)

    m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium solution (100mM)

    		 DNA/RNA Synthesis Others
    3'OMe-m7GpppAmpG ammonium solution (100mM) is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .
    3'OMe-m7GpppAmpG (ammonium) solution (100mM)
  • HY-W590681
    113-O12B

    		Liposome Others
    113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
    113-O12B
  • HY-W440910
    DSPE-PEG-Cy3, MW 5000

    		Liposome Others
    DSPE-PEG-Cy3, MW 5000 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy3, MW 5000
  • HY-W440909
    DSPE-PEG-Cy3, MW 3400

    		Liposome Others
    DSPE-PEG-Cy3, MW 3400 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy3, MW 3400
  • HY-W440834
    DSPE-PEG-azide (MW 5000)

    		Biochemical Assay Reagents Liposome Others
    DSPE-PEG-Azide, MW 5000 is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine. Reagent grade, for research use only.
    DSPE-PEG-azide (MW 5000)
  • HY-W440913
    DSPE-PEG-Cy5, MW 5000

    		Liposome Others
    DSPE-PEG-Cy5, MW 5000 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy5, MW 5000
  • HY-W440899
    DSPE-PEG-SPDP (MW 1000)

    		Liposome Others
    DSPE-PEG-SPDP, MW 1000 is a thiol reactive PEG lipid. The polymer is amphiphilic and spontaneously forms lipid bilayer in water. It can be used to encapsulate nutrients or therapeutics for targeted drug delivery, for example mRNA or DNA vaccine, liposomal doxorubicin for anti tumor. Reagent grade, for research use only.
    DSPE-PEG-SPDP (MW 1000)
  • HY-W440912
    DSPE-PEG-Cy5, MW 3400

    		Liposome Others
    DSPE-PEG-Cy5, MW 3400 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy5, MW 3400
  • HY-W440893
    DSPE-PEG-OH (MW 5000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-OH, MW 5000 is a linear phospholipid PEG polymer. The lipid tails allow encapsulation of hdyrophobic therapeutics while the PEG chain maintains its hydrophilicity. The polymer can be used for drug nanocarrier, such as liposomal anti cancer drug or mRNA/DNA vaccine. Reagent grade, for research use only.
    DSPE-PEG-OH (MW 5000)
  • HY-W440919
    DSPE-PEG-Rhodamine, MW 2000

    		Liposome Others
    DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
    DSPE-PEG-Rhodamine, MW 2000
  • HY-D2887
    RB-PEG-DSPE (MW 400)

    Rhodamine B-PEG-DSPE (MW 400)

    		 Fluorescent Dye Others
    RB-PEG-DSPE (MW 400) (Rhodamine B-PEG-DSPE (MW 400)) is a PEG phospholipid labeled Rhodamine B (HY-Y0016). RB-PEG-DSPE (MW 400) can be used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 546/610 nm) .
    RB-PEG-DSPE (MW 400)
  • HY-D2887B
    RB-PEG-DSPE (MW 1000)

    Rhodamine B-PEG-DSPE (MW 1000)

    		 Fluorescent Dye Others
    RB-PEG-DSPE (MW 1000) (Rhodamine B-PEG-DSPE (MW 1000)) is a PEG phospholipid labeled Rhodamine B (HY-Y0016). RB-PEG-DSPE (MW 1000) can be used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 546/610 nm) .
    RB-PEG-DSPE (MW 1000)
  • HY-D2887A
    RB-PEG-DSPE (MW 600)

    Rhodamine B-PEG-DSPE (MW 600)

    		 Fluorescent Dye Others
    RB-PEG-DSPE (MW 600) (Rhodamine B-PEG-DSPE (MW 4600)) is a PEG phospholipid labeled Rhodamine B (HY-Y0016). RB-PEG-DSPE (MW 600) can be used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 546/610 nm) .
    RB-PEG-DSPE (MW 600)
  • HY-D2887H
    RB-PEG-DSPE (MW 10000)

    Rhodamine B-PEG-DSPE (MW 10000)

    		 Fluorescent Dye Others
    RB-PEG-DSPE (MW 10000) (Rhodamine B-PEG-DSPE (MW 10000)) is a PEG phospholipid labeled Rhodamine B (HY-Y0016). RB-PEG-DSPE (MW 10000) can be used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 546/610 nm) .
    RB-PEG-DSPE (MW 10000)
  • HY-D2887C
    RB-PEG-DSPE (MW 2000)

    Rhodamine B-PEG-DSPE (MW 2000)

    		 Fluorescent Dye Others
    RB-PEG-DSPE (MW 2000) (Rhodamine B-PEG-DSPE (MW 2000)) is a PEG phospholipid labeled Rhodamine B (HY-Y0016). RB-PEG-DSPE (MW 2000) can be used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 546/610 nm) .
    RB-PEG-DSPE (MW 2000)
  • HY-D2887D
    RB-PEG-DSPE (MW 3400)

    Rhodamine B-PEG-DSPE (MW 3400)

    		 Fluorescent Dye Others
    RB-PEG-DSPE (MW 3400) (Rhodamine B-PEG-DSPE (MW 3400)) is a PEG phospholipid labeled Rhodamine B (HY-Y0016). RB-PEG-DSPE (MW 3400) can be used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 546/610 nm) .
    RB-PEG-DSPE (MW 3400)
  • HY-D2887E
    RB-PEG-DSPE (MW 5000)

    Rhodamine B-PEG-DSPE (MW 5000)

    		 Fluorescent Dye Others
    RB-PEG-DSPE (MW 5000) (Rhodamine B-PEG-DSPE (MW 5000)) is a PEG phospholipid labeled Rhodamine B (HY-Y0016). RB-PEG-DSPE (MW 5000) can be used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 546/610 nm) .
    RB-PEG-DSPE (MW 5000)
  • HY-153376
    LNP Lipid-6

    		Liposome Others
    LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .
    LNP Lipid-6
  • HY-153375
    LNP Lipid-5

    		Liposome Others
    LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .
    LNP Lipid-5
  • HY-D2526
    Cy3 IRGD-PEG-DSPE

    		Fluorescent Dye Liposome Others
    Cy3 IRGD-PEG-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3 IRGD-PEG-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    Cy3 IRGD-PEG-DSPE
  • HY-W441003
    DSPE-PEG-IA (MW 2000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-IA, MW 2000 is a thiol reactive phospholipid polyPEG. The iodoacetyll group is reactive with thiol to produce a thioether linkage. The polymer can self-assemble in water to form lipid bilayer and can be used to encapsulate drugs in targeted delivery application, such as liposomal doxorubicin as an anti cancer drug or mRNA vaccine. Reagent grade, for research use only.
    DSPE-PEG-IA (MW 2000)
  • HY-W440907
    DSPE-PEG-Vinylsulfone (MW 5000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-Vinylsulfone, MW 5000 is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine. Reagent grade, for research use only.
    DSPE-PEG-Vinylsulfone (MW 5000)
  • HY-W440884
    DSPE-PEG-Ald (MW 3400)

    		Biochemical Assay Reagents Others
    DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
    DSPE-PEG-Ald (MW 3400)

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