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Results for "

hydratase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA synthetase (1) Biochemical Assay Reagents (3) Drug Metabolite (1) Endogenous Metabolite (2) Mitochondrial Metabolism (4) Reference Standards (2)
By Research Areas:	Cancer (2) Metabolic Disease (4)

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Targets Recommended: Enolase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100004

*Fumarate hydratase-IN-1* 5+ Cited Publications	Mitochondrial Metabolism	Cancer
Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC₅₀ of 2.2 μM .

HY-100005A

*Fumarate hydratase-IN-2 sodium salt* 1 Publications Verification	Mitochondrial Metabolism	Cancer
Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor (K_i=4.5 μM) with nutrient-dependent cytotoxicity .

HY-W020215

Tricarballylic acid	Mitochondrial Metabolism Endogenous Metabolite	Metabolic Disease
Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a K_i value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .

HY-Y1416

3-(1-Cyanoethyl)benzoic acid DF2107Y	Biochemical Assay Reagents	Others
3-(1-Cyanoethyl)benzoic acid (DF2107Y) is a benzoic acid that can be used to screen cobalt containing nitrile hydratases (NHases) .

HY-116037A

trans-10-Heptadecenoic acid	Biochemical Assay Reagents	Others
trans-10-Heptadecenoic acid is a trans-fatty acid. trans-10-Heptadecenoic acid synthesizes polyhydroxy-chain alkanoates under the action of 2, 4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase. In the absence of 2, 4-dienyl-CoA reductase, trans-10-Heptadecenoic acid is degraded by enyl-CoA hydratase II of the multifunctional enzyme (MFE). trans-10-Heptadecenoic acid leads to massive intracellular carbon outflow through reductase dependent and direct MFE dependent pathways .

HY-W020215R

Tricarballylic acid (Standard)	Reference Standards Mitochondrial Metabolism Endogenous Metabolite	Metabolic Disease
Tricarballylic acid (Standard) is the analytical standard of Tricarballylic acid (HY-W020215). This product is intended for research and analytical applications. Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a K_i value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .

HY-W712674

HMG-CoA 3-Hydroxy-3-methylglutaryl-CoA	Acetyl-CoA synthetase	Metabolic Disease
HMG-CoA is a product generated by the hydration reaction of (E)-3-methylglutaconyl-CoA (MG-CoA) catalyzed by methylglutaconyl-CoA hydratase (MGCH) .

HY-N13366

3-Methylcrotonyl CoA	Drug Metabolite	Metabolic Disease
3-Methylcrotonyl CoA is a key metabolic intermediate in the leucine degradation pathway, converted to 3-Methylglutaconyl CoA by 3-Methylcrotonyl CoA Carboxylase. Normally, 3-Methylglutaconyl CoA is catalyzed by 3-Methylglutaconyl-CoA Hydratase into 3-Hydroxy-3-methylglutaryl-CoA (HMG CoA). However, mutations in 3-Methylglutaconyl-CoA Hydratase lead to the accumulation of 3-Methylglutaconyl CoA, causing metabolic disorders associated with 3MGA-uria. 3-Methylcrotonyl CoA is useful for research into metabolic diseases related to the leucine degradation pathway .

HY-Y1416R

3-(1-Cyanoethyl)benzoic acid (Standard) DF2107Y (Standard)	Biochemical Assay Reagents Reference Standards	Others
3-(1-Cyanoethyl)benzoic acid (Standard) is the analytical standard of 3-(1-Cyanoethyl)benzoic acid. This product is intended for research and analytical applications. 3-(1-Cyanoethyl)benzoic acid (DF2107Y) is a benzoic acid that can be used to screen cobalt containing nitrile hydratases (NHases) .

Tricarballylic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Mitochondrial Metabolism Endogenous Metabolite
Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a K_i value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .

trans-10-Heptadecenoic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Biochemical Assay Reagents
trans-10-Heptadecenoic acid is a trans-fatty acid. trans-10-Heptadecenoic acid synthesizes polyhydroxy-chain alkanoates under the action of 2, 4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase. In the absence of 2, 4-dienyl-CoA reductase, trans-10-Heptadecenoic acid is degraded by enyl-CoA hydratase II of the multifunctional enzyme (MFE). trans-10-Heptadecenoic acid leads to massive intracellular carbon outflow through reductase dependent and direct MFE dependent pathways .

Tricarballylic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Mitochondrial Metabolism Endogenous Metabolite
Tricarballylic acid (Standard) is the analytical standard of Tricarballylic acid (HY-W020215). This product is intended for research and analytical applications. Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a K_i value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .

HMG-CoA 3-Hydroxy-3-methylglutaryl-CoA	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Acetyl-CoA synthetase
HMG-CoA is a product generated by the hydration reaction of (E)-3-methylglutaconyl-CoA (MG-CoA) catalyzed by methylglutaconyl-CoA hydratase (MGCH) .

3-Methylcrotonyl CoA	Structural Classification Natural Products Source classification Endogenous metabolite	Drug Metabolite
3-Methylcrotonyl CoA is a key metabolic intermediate in the leucine degradation pathway, converted to 3-Methylglutaconyl CoA by 3-Methylcrotonyl CoA Carboxylase. Normally, 3-Methylglutaconyl CoA is catalyzed by 3-Methylglutaconyl-CoA Hydratase into 3-Hydroxy-3-methylglutaryl-CoA (HMG CoA). However, mutations in 3-Methylglutaconyl-CoA Hydratase lead to the accumulation of 3-Methylglutaconyl CoA, causing metabolic disorders associated with 3MGA-uria. 3-Methylcrotonyl CoA is useful for research into metabolic diseases related to the leucine degradation pathway .

Species:	Human (8) Virus (1) Mouse (2)
Tag:	His (10) SUMO (1) Tag Free (3) GST (2)
Source:	HEK293 (1) Sf9 insect cells (4) E. coli (8)

Cat. No.	Compare	Product Name	Species	Source

HY-P70267

	*Fumarate hydratase/FH Protein, Human* rHuFumarate hydratase/FH; Fumarate hydratase Mitochondrial; Fumarase; FH	Human	E. coli
	The fumarate hydratase/FH protein plays a key role in cellular processes as it catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle, which is essential for energy production through the production of NADH . Fumarate hydratase/FH Protein, Human is the recombinant human-derived Fumarate hydratase/FH protein, expressed by E. coli , with tag free.

HY-P73062

	*Fumarate Hydratase/FH Protein, Human (His)* Fumarate hydratase; Fumarase; HsFH; FH	Human	E. coli
	The fumarate hydratase/FH protein plays a key role in cellular processes as it catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle, which is essential for energy production through the production of NADH . Fumarate Hydratase/FH Protein, Human (His) is the recombinant human-derived Fumarate Hydratase/FH protein, expressed by E. coli , with C-His labeled tag.

HY-P74432

	Aconitase 2/ACO2 Protein, Human (sf9, His-GST) Aconitate hydratase; Aconitase; ACO2	Human	Sf9 insect cells
	Aconitase 2/ACO2 Protein, an enzyme, plays a vital role in the tricarboxylic acid cycle and energy production. Dysregulation of Aconitase 2/ACO2 Protein has been associated with mitochondrial dysfunction and oxidative stress. Targeting Aconitase 2/ACO2 Protein may provide potential therapeutic strategies by regulating energy metabolism, reducing oxidative damage, and improving mitochondrial function. Aconitase 2/ACO2 Protein, Human (sf9, His-GST) is the recombinant human-derived Aconitase 2/ACO2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P75227

	EPHX2 Protein, Human (sf9, His) Bifunctional epoxide hydrolase 2; CEH; Epoxide hydratase; SHE; EPHX2	Human	Sf9 insect cells
	The EPHX2 protein is a bifunctional enzyme that displays epoxide hydrolase activity in its C-terminal domain, which is critical for xenobiotic metabolism. It degrades toxic epoxides and affects homeostatic levels of physiological mediators. EPHX2 Protein, Human (sf9, His) is the recombinant human-derived EPHX2 protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P75560

	Aconitase 1/ACO1 Protein, Human (sf9, His) Cytoplasmic aconitate hydratase; Aconitase; IRP1; IRE-BP 1; ACO1; IREB1	Human	Sf9 insect cells
	The ACO1 protein is a bifunctional iron sensor that dynamically adapts to cellular iron levels. Under conditions of iron deficiency, it is converted to mRNA binding and regulates iron-related gene expression. Aconitase 1/ACO1 Protein, Human (sf9, His) is the recombinant human-derived Aconitase 1/ACO1 protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P74431

	Aconitase 2/ACO2 Protein, Mouse (sf9, His-GST) Aconitate hydratase; Aconitase; ACO2	Mouse	Sf9 insect cells
	Aconitase 2 (ACO2) protein catalyzes the isomerization of citric acid to isocitrate through the intermediate aconitate, playing a crucial role in cellular metabolism. This enzyme activity is a key step in the tricarboxylic acid (TCA) cycle, a central pathway for energy production and generation of metabolic intermediates. Aconitase 2/ACO2 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived Aconitase 2/ACO2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P75559

	acnB Protein, E. coli Aconitate hydratase B; ACN; Aconitase; RNA-binding protein; acnB; yacI; yacJ	Virus	E. coli
	The acnB protein coordinates short-chain fatty acid catabolism through the TCA pathway and 2-methylcitric acid cycle I, demonstrating catalytic versatility. It is involved in the reversible isomerization of citric acid to isocitrate and the hydration of 2-methyl-cis-aconitic acid. acnB Protein, E. coli is the recombinant Virus-derived acnB protein, expressed by E. coli , with tag free.

HY-P702121

	fum Protein, Corynebacterium glutamicum fumC; Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase	Others	E. coli
	Fum proteins crucially catalyze the interconversion of fumarate to L-malate in the tricarboxylic acid (TCA) cycle, maintaining metabolite flow in cellular energy metabolism. This critical step, if precisely regulated, helps generate energy and generates intermediates critical to cellular processes. fum Protein, Corynebacterium glutamicum is the recombinant fum protein, expressed by E. coli , with tag free.

HY-P702122

	fum Protein, Corynebacterium glutamicum (His) fumC; Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase	Others	E. coli
	Fum proteins crucially catalyze the interconversion of fumarate to L-malate in the tricarboxylic acid (TCA) cycle, maintaining metabolite flow in cellular energy metabolism. This critical step, if precisely regulated, helps generate energy and generates intermediates critical to cellular processes. fum Protein, Corynebacterium glutamicum (His) is the recombinant fum protein, expressed by E. coli , with N-6*His labeled tag.

HY-P703734

	CA2/Carbonic anhydrase II Protein, Mouse (HEK293, His) Carbonic anhydrase 2; Carbonate dehydratase II; Carbonic anhydrase II; CA-II; Cyanamide hydratase CA2; 4.2.1.69; Ca2; CA-II	Mouse	HEK293

HY-P70260

	Enolase 1/ENO1 Protein, Human (His, solution) rHuAlpha-enolase, His; Alpha-enolase; 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding protein; ENO1	Human	E. coli
	The ENO1 protein converts 2-phosphoglycerate to phosphoenolpyruvate and is involved in growth control, hypoxia tolerance, and allergic responses. It acts as a receptor and activator of plasminogen, stimulating immunoglobulin production. ENO1 binds to the myc promoter as a transcriptional repressor and may function as a tumor suppressor. Enolase 1/ENO1 Protein, Human (His, solution) is the recombinant human-derived ENO1, expressed by E. coli , with C-His labeled tag.

HY-P70260A

	Enolase 1/ENO1 Protein, Human (C-His) rHuAlpha-enolase, His; Alpha-enolase; 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding protein; ENO1	Human	E. coli
	The ENO1 protein converts 2-phosphoglycerate to phosphoenolpyruvate and is involved in growth control, hypoxia tolerance, and allergic responses. It acts as a receptor and activator of plasminogen, stimulating immunoglobulin production. ENO1 binds to the myc promoter as a transcriptional repressor and may function as a tumor suppressor. Enolase 1/ENO1 Protein, Human (C-His) is the recombinant human-derived Enolase 1/ENO1 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P72184

	EPHX1 Protein, Human (His-SUMO) EPHX 1; EPHX; Ephx1; EPOX; Epoxide hydratase; Epoxide hydrolase 1; Epoxide hydrolase 1 microsomal xenobiotic; Epoxide hydroxylase 1; Epoxide hydroxylase 1 microsomal xenobiotic; HYEP_HUMAN; HYL1; MEH; Microsomal epoxide hydrolase	Human	E. coli
	The EPHX1 protein is an important biotransformation enzyme that hydrolyzes aromatic hydrocarbons and aliphatic epoxides by catalyzing the transaddition of water. This makes the epoxide less reactive and more water-soluble. EPHX1 Protein, Human (His-SUMO) is the recombinant human-derived EPHX1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

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HY-P82406

	Aconitase 2 Antibody (YA2151) Aconitate hydratase; mitochondrial; Aconitase; Citrate hydro-lyase	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	Aconitase 2 Antibody (YA2151) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2151), targeting Aconitase 2, with a predicted molecular weight of 85 kDa (observed band size: 85 kDa). Aconitase 2 Antibody (YA2151) can be used for WB, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

HY-P80672

	FH Antibody (YA763) Fumarate hydratase; mitochondrial; Fumarase	WB, ICC/IF	Human, Mouse, Rat
	FH Antibody (YA763) is a non-conjugated and Mouse origined monoclonal antibody about 55 kDa, targeting to FH (2A3). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P85661

	FH Antibody (YA5353) Fumarate hydratase, mitochondrial; Fumarase	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	FH Antibody (YA5353) is a mouse-derived and non-conjugated monoclonal antibody, targeting to FH. It can be applicated for WB, IHC-P, ICC/IF assays, in the background of human, mouse, rat.

HY-P83105

	Aconitase 1 Antibody (YA2850) ACO1; IREB1; Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1	WB, ICC/IF	Human, Mouse, Rat
	Aconitase 1 Antibody (YA2850) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2850), targeting Aconitase 1, with a predicted molecular weight of 98 kDa (observed band size: 98 kDa). Aconitase 1 Antibody (YA2850) can be used for WB, ICC/IF experiment in human, mouse, rat background.

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hydratase

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