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Results for "

hepatoprotective activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (3) Aldose Reductase (2) AMPK (6) Amyloid-β (3) Antibiotic (1) Apoptosis (36) Aurora Kinase (2) Autophagy (13) Bacterial (15) Bcl-2 Family (2) Caspase (2) CDK (3) Chloride Channel (1) COX (7) Cryptochrome (2) Cytochrome P450 (4) DNA/RNA Synthesis (3) Endogenous Metabolite (16) Epigenetic Reader Domain (2) ERK (3) Estrogen Receptor/ERR (2) Fungal (4) FXR (2) GLUT (2) Glycosidase (4) HDAC (1) Heme Oxygenase (HO) (2) HIF/HIF Prolyl-Hydroxylase (4) HIV (2) iGluR (3) Influenza Virus (4) Integrin (2) Interleukin Related (1) Isotope-Labeled Compounds (6) JAK (1) JNK (1) Keap1-Nrf2 (7) MMP (3) Necroptosis (4) NF-κB (9) NO Synthase (4) Oxidative Phosphorylation (1) p38 MAPK (2) Parasite (1) PARP (3) Phosphodiesterase (PDE) (3) PI3K (2) PPAR (2) Proteasome (1) Reactive Oxygen Species (12) Reference Standards (2) Reverse Transcriptase (2) Ribosomal S6 Kinase (RSK) (2) ROS Kinase (2) Syk (2) TNF Receptor (1) Toll-like Receptor (TLR) (2) Topoisomerase (3) Tyrosinase (2) VEGFR (2) Virus Protease (2) Xanthine Oxidase (2)
By Research Areas:	Cancer (64) Cardiovascular Disease (16) Endocrinology (2) Infection (28) Inflammation/Immunology (51) Metabolic Disease (28) Neurological Disease (23)
Oligonucleotides:	Cholesterol (1)

103

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N5092

7-Methylcoumarin	Bacterial	Metabolic Disease
7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N15155

Vitexin 7-O-β-D-glucopyranoside Vitexin 7-glucoside	Others	Metabolic Disease
Vitexin 7-O-β-D-glucopyranoside (Vitexin 7-glucoside) is a flavone glycoside found in Beta vulgaris var. cicla. Vitexin 7-O-β-D-glucopyranoside shows a hepatoprotective activity in primary cultured rat hepatocytes with Carbon tetrachloride (CCl4) (HY-Y0298)-induced cell toxicity .

HY-N1506

Ganodermanontriol	Epigenetic Reader Domain p38 MAPK	Cancer
Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity .

HY-N1989

Bacoside A	Others	Metabolic Disease
Bacoside A exhibits hepatoprotective activity .

HY-N13159

Goodyeroside A	Others	Inflammation/Immunology
Goodyeroside A is a glycoside compound derived from the plant Goodyera that exhibits significant hepatoprotective activity. It can inhibit liver damage induced by carbon tetrachloride (HY-Y0298) in primary cultured rat hepatocytes .

HY-N10436

Anti-inflammatory agent 30	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10435

Anti-inflammatory agent 29	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 29 (Compound 7) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10434

Anti-inflammatory agent 28	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 28 (Compound 9) is an anti-inflammatory agent with hepatoprotective activity .

HY-N5092R

7-Methylcoumarin (Standard)	Reference Standards Others	Metabolic Disease
7-Methylcoumarin (Standard) is the analytical standard of 7-Methylcoumarin. This product is intended for research and analytical applications. 7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N1324

Sanggenon N	Others	Others
Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC₅₀ of 23.45 μM .

HY-N0055

Chlorogenic acid Maximum Cited Publications 18 Publications Verification 3-O-Caffeoylquinic acid; Heriguard; NSC-407296	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-N0055R

Chlorogenic acid (Standard)	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite	Infection Inflammation/Immunology Cancer
Chlorogenic acid (Standard) is the analytical standard of Chlorogenic acid. This product is intended for research and analytical applications. Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-W027126

Hepatoprotective agent-2	Apoptosis	Metabolic Disease
Hepatoprotective agent-2 (compound 2a), a 4-phenyl-tetrahydroquinoline derivative, displays a remarkable hepatoprotective effect. Hepatoprotective agent-2 has antiapoptotic activity. Hepatoprotective agent-2 notably prevents the chemically induced elevation of hepatic indicators associated with liver injury .

HY-N11660

weak Hepatoprotective agent-1	Others	Metabolic Disease
weak Hepatoprotective agent-1 (Compound 11) is a natural product that can be isolated from the fruits of Arctium lappa L.. weak Hepatoprotective agent-1 exhibits weak hepatoprotective activities at a concentration of 10 μM .

HY-N2155

Tubuloside A	Others	Metabolic Disease
Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-N12442

Sarmenoside III	Others	Metabolic Disease
Sarmenoside III is a flavonol glycoside with hepatoprotective activity isolated from Sedum sarmentosum.

HY-N9880

Tamarixin	Bacterial	Infection Inflammation/Immunology Cancer
Tamarixin is flavonoid that isolated from Astragalus tanae Sosn that has hepatoprotective, antioxidant, anticancer, and antimicrobial activities .

HY-N2155R

Tubuloside A (Standard)	Others	Metabolic Disease
Tubuloside A (Standard) is the analytical standard of Tubuloside A. This product is intended for research and analytical applications. Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-121174

Alaternin Catharticin	NO Synthase CDK Tyrosinase Reactive Oxygen Species	Metabolic Disease
Alaternin (Catharticin) is an anthraquinone compound with antioxidant and hepatoprotective activities. Alaternin has an inhibitory activity against hydroxyl radicals generated in a cell-free chemical system (FeSO₄/H₂O₂) with an IC₅₀ value of 3.05 μM. Alaternin exhibits hepatoprotective activity against Tacrine (HY-111338)-induced toxicity in human hepatic HepG2 cells with an EC₅₀ value of 4.02 μM .

HY-139637

(±)-Silybin Silibinin (mixture of Silybin A and Silybin B)	Apoptosis	Cancer
(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N1616

1β-Hydroxyeuscaphic acid	Apoptosis	Others
1β-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis .

HY-150521

Hispolon	Antibiotic	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities .

HY-N1214

Squalene Super Squalene; trans-Squalene; AddaVax	Endogenous Metabolite Reactive Oxygen Species Fungal	Infection Cardiovascular Disease Cancer
Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-129577

Aplysin	Necroptosis	Inflammation/Immunology Cancer
Aplysin is a brominated sesquiterpene with an isoprene backbone that exhibits hepatoprotective, immunomodulatory, and antitumor activities. Aplysin effectively prevents spontaneous pancreatic necrosis and inflammatory responses in NOD mice .

HY-N0344

Farrerol 2 Publications Verification	Others	Neurological Disease Inflammation/Immunology Cancer
Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .

HY-N0779A

Silybin 3 Publications Verification Silibinin	Apoptosis	Inflammation/Immunology Cancer
Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N0017

Bergenin 4 Publications Verification Cuscutin	NF-κB Autophagy Apoptosis Bacterial Fungal Virus Protease	Infection Inflammation/Immunology Cancer
Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties .

HY-162583

PDE4-IN-17	Phosphodiesterase (PDE)	Inflammation/Immunology
PDE4-IN-17 (compound 4e) is a potent PDE4 inhibitor. PDE4-IN-17 inhibits PDE4B and PDE4D with IC₅₀s of 10.0 and 15.2 nM, respectively. PDE4-IN-17 has good oral bioavailability (F=66%) and longer half-life (t_1/2=2.0 h) in SD rats .

HY-N12706

Heilaohuguosu G	Endogenous Metabolite	Endocrinology
Heilaohuguosu G (compound 7) is a cyclolignan with hepatoprotective activity. Heilaohuguosu G against APAP toxicity with cell survival rates at 10 μM of 45.7% in HepG-2 cells .

HY-118383

Agathisflavone	Parasite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats .

HY-N3646

Cudratricusxanthone A	Others	Others Neurological Disease Inflammation/Immunology Cancer
Cudratricusxanthone A is isolated from Cudrania tricuspidata, and has anti-inflammatory, hepatoprotective, and anti-proliferative activities. Cudratricusxanthone A inhibits osteoclast differentiation and function in RAW 264.7 cells and mouse bone marrow monocytes .

HY-N0222

Avicularin 4 Publications Verification	COX NF-κB PPAR ERK GLUT Apoptosis	Infection Neurological Disease Inflammation/Immunology Cancer
Avicularin is an orally active flavonoid. Avicularin inhibits NF-κB (p65), COX-2 and PPAR-γ activities. Avicularin has anti-inflammatory, anti-infectious anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities .

HY-N1214S

Squalene-d6 Super Squalene-d₆; trans-Squalene-d₆; AddaVax-d₆	Isotope-Labeled Compounds	Others
Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-N2094

Genipin 1-β-D-gentiobioside 1 Publications Verification Genipin 1-gentiobioside; Genipin 1-β-gentiobioside; Genipin gentiobioside	Others	Inflammation/Immunology
Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.

HY-N0344R

Farrerol (Standard)	Akt ERK JNK NF-κB	Infection Inflammation/Immunology Cancer
Farrerol (Standard) is the analytical standard of Farrerol. This product is intended for research and analytical applications. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .

HY-N4113

Glycycoumarin	Keap1-Nrf2 AMPK	Cancer
Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

HY-N2000

Bellidifolin	HIV	Infection Inflammation/Immunology Cancer
Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities . Bellidifolin also acts as a viral protein R (Vpr) inhibitor .

HY-N9966

Sanggenol O	Others	Others
Sanggenol O? is an active product that can be extracted from Morus alba. Sanggenol O? has hepatoprotective and neuroprotective activities with EC₅₀s more than 80 μM in HepG2 and HT22 cells .

HY-125129

Carlinoside	Keap1-Nrf2	Others
Carlinoside is a flavone glycoside with hepatoprotective efficiency. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Carlinoside has the potential to intervene hyperbilirubinemia due to liver dysfunction .

HY-N0691

Schisandrin 3 Publications Verification Schizandrin; Schizandrol; Schizandrol-A	Autophagy	Inflammation/Immunology Cancer
Schisandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schisandrin exhibits antioxidant, hepatoprotective, anti-cancer and anti-inflammatory activities. Schisandrin also can reverses memory impairment in rats .

HY-N1521

Rehmannic acid Lantadene A	Others	Inflammation/Immunology
Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent .

HY-N9096

Gentiside B	Bacterial	Neurological Disease
Gentiside B has neuritogenic activity and induce neurite outgrowth. Gentiside B can be isolated from the root and rhizome of Gentiana rigescens. Gentiana has hepatoprotective, anti-inflammatory, analgesic, antiproliferative and antimicrobial effects .

HY-N0823

Lithospermic acid 3 Publications Verification (+)-Lithospermic acid	NO Synthase AMPK Keap1-Nrf2 Xanthine Oxidase Apoptosis	Cardiovascular Disease Inflammation/Immunology
Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl₄)-induced acute liver damage in vitro and in vivo .

HY-N1214R

Squalene (Standard)	Endogenous Metabolite Reactive Oxygen Species Fungal	Infection Cardiovascular Disease
Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-W068771

(E)-3-(4-Methoxyphenyl)acrylic acid	Endogenous Metabolite	Neurological Disease Metabolic Disease
(E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities .

HY-N2412

Irisolidone	Chloride Channel	Neurological Disease Cancer
Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC₅₀=9.8 μM) .

HY-N0017R

Bergenin (Standard)	NF-κB Autophagy Apoptosis Bacterial Fungal Virus Protease	Infection Inflammation/Immunology Cancer
Bergenin (Standard) is the analytical standard of Bergenin. This product is intended for research and analytical applications. Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties .

HY-N7543

Schisantherin D	HIV	Infection
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC₅₀ of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects .

HY-N0779AR

Silybin (Standard)	Apoptosis	Inflammation/Immunology Cancer
Silybin (Standard) is the analytical standard of Silybin. This product is intended for research and analytical applications. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-146058

NF-κB/PON1-IN-1	NF-κB Reactive Oxygen Species	Cancer
NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC₅₀ = 45.76 µM) and hepatoprotective activities .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N5092

7-Methylcoumarin	Microorganisms Source classification Coumarins Metabolic Disease Phenylpropanoids Disease Research Fields	Bacterial
7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N15155

Vitexin 7-O-β-D-glucopyranoside Vitexin 7-glucoside	Structural Classification Flavonoids Flavones Source classification Amaranthaceae Plants Beta vulgaris var. cicla L. Saccharides Monosaccharides	Others
Vitexin 7-O-β-D-glucopyranoside (Vitexin 7-glucoside) is a flavone glycoside found in Beta vulgaris var. cicla. Vitexin 7-O-β-D-glucopyranoside shows a hepatoprotective activity in primary cultured rat hepatocytes with Carbon tetrachloride (CCl4) (HY-Y0298)-induced cell toxicity .

HY-N1506

Ganodermanontriol	Structural Classification Classification of Application Fields Polyporaceae Source classification Plants Endogenous metabolite Other Terpenoids Human Gut Microbiota Metabolites Microorganisms Terpenoids Ganoderma lucidum (Leyss. Ex Fr.) Karst. Disease Research Fields Cancer	Epigenetic Reader Domain p38 MAPK
Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity .

HY-N1989

Bacoside A	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Scrophulariaceae Metabolic Disease Plants Disease Research Fields Bacopa monnieri (Linn.) Wettst.	Others
Bacoside A exhibits hepatoprotective activity .

HY-N13159

Goodyeroside A	Structural Classification Crocus sativus Linn. Iridaceae Source classification Plants Saccharides Monosaccharides	Others
Goodyeroside A is a glycoside compound derived from the plant Goodyera that exhibits significant hepatoprotective activity. It can inhibit liver damage induced by carbon tetrachloride (HY-Y0298) in primary cultured rat hepatocytes .

HY-N10436

Anti-inflammatory agent 30	Source classification Phenols Dicerothamnus rhinocerotis Plants Umbelliferae	Others
Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10435

Anti-inflammatory agent 29	Source classification Phenols Dicerothamnus rhinocerotis Plants Umbelliferae	Others
Anti-inflammatory agent 29 (Compound 7) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10434

Anti-inflammatory agent 28	Source classification Phenols Dicerothamnus rhinocerotis Plants Umbelliferae	Others
Anti-inflammatory agent 28 (Compound 9) is an anti-inflammatory agent with hepatoprotective activity .

HY-N5092R

7-Methylcoumarin (Standard)	Microorganisms Source classification Coumarins Phenylpropanoids	Reference Standards Others
7-Methylcoumarin (Standard) is the analytical standard of 7-Methylcoumarin. This product is intended for research and analytical applications. 7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N1324

Sanggenon N	Structural Classification Flavanonols Flavonoids Source classification Phenols Polyphenols Plants Moraceae Morus alba Linn.	Others
Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC₅₀ of 23.45 μM .

HY-N0055

Chlorogenic acid Maximum Cited Publications 18 Publications Verification 3-O-Caffeoylquinic acid; Heriguard; NSC-407296	Structural Classification Caprifoliaceae Classification of Application Fields Lonicera japonica Thunb. Anti-aging Source classification Plants Endogenous metabolite Infection Human Gut Microbiota Metabolites Microorganisms Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Inflammation/Immunology Disease Research Fields Cancer	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-N0055R

Chlorogenic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Caprifoliaceae Simple Phenylpropanols Lonicera japonica Thunb. Source classification Phenols Polyphenols Phenylpropanoids Plants Endogenous metabolite	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite
Chlorogenic acid (Standard) is the analytical standard of Chlorogenic acid. This product is intended for research and analytical applications. Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-N11660

weak Hepatoprotective agent-1	Structural Classification Source classification Lignans Phenylpropanoids Plants Compositae Gueldenstaedtia verna (Georgi) Boriss.	Others
weak Hepatoprotective agent-1 (Compound 11) is a natural product that can be isolated from the fruits of Arctium lappa L.. weak Hepatoprotective agent-1 exhibits weak hepatoprotective activities at a concentration of 10 μM .

HY-N2155

Tubuloside A	Structural Classification Classification of Application Fields Simple Phenylpropanols Cistanche deserticola Ma Source classification Phenols Polyphenols Orobanchaceae Metabolic Disease Phenylpropanoids Plants Disease Research Fields	Others
Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-N12442

Sarmenoside III	Structural Classification Source classification Phenols Polyphenols Plants Capparidaceae Cleome chelidonii L.f.	Others
Sarmenoside III is a flavonol glycoside with hepatoprotective activity isolated from Sedum sarmentosum.

HY-N9880

Tamarixin	Structural Classification Monophenols Flavonoids Flavones Leguminosae Source classification Phenols Plants Saccharides Astragalus membranaceus (Fisch.) Bunge Monosaccharides	Bacterial
Tamarixin is flavonoid that isolated from Astragalus tanae Sosn that has hepatoprotective, antioxidant, anticancer, and antimicrobial activities .

HY-N2155R

Tubuloside A (Standard)	Structural Classification Simple Phenylpropanols Cistanche deserticola Ma Source classification Phenols Polyphenols Orobanchaceae Phenylpropanoids Plants	Others
Tubuloside A (Standard) is the analytical standard of Tubuloside A. This product is intended for research and analytical applications. Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-121174

Alaternin Catharticin	Structural Classification Flavonoids Source classification Plants Rhamnaceae Rhamnus saxatilis X. H. Song	NO Synthase CDK Tyrosinase Reactive Oxygen Species
Alaternin (Catharticin) is an anthraquinone compound with antioxidant and hepatoprotective activities. Alaternin has an inhibitory activity against hydroxyl radicals generated in a cell-free chemical system (FeSO₄/H₂O₂) with an IC₅₀ value of 3.05 μM. Alaternin exhibits hepatoprotective activity against Tacrine (HY-111338)-induced toxicity in human hepatic HepG2 cells with an EC₅₀ value of 4.02 μM .

HY-139637

(±)-Silybin Silibinin (mixture of Silybin A and Silybin B)	Structural Classification Flavanonols Flavonoids Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Apoptosis
(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N1616

1β-Hydroxyeuscaphic acid	Triterpenes other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Apoptosis
1β-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis .

HY-150521

Hispolon	Infection Structural Classification Microorganisms Classification of Application Fields Phenols Polyphenols Metabolic Disease Disease Research Fields Cancer	Antibiotic
Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities .

HY-N1214

Squalene Super Squalene; trans-Squalene; AddaVax	Cardiovascular Disease Triterpenes Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms other families Animals Terpenoids Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species Fungal
Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-129577

Aplysin	Structural Classification Natural Products Animals Source classification	Necroptosis
Aplysin is a brominated sesquiterpene with an isoprene backbone that exhibits hepatoprotective, immunomodulatory, and antitumor activities. Aplysin effectively prevents spontaneous pancreatic necrosis and inflammatory responses in NOD mice .

HY-N0344

Farrerol 2 Publications Verification	Structural Classification Rhododendron dauricum Linn. Neurological Disease Classification of Application Fields Source classification Plants Flavonoids Flavonones Phenols Polyphenols Ericaceae Inflammation/Immunology Disease Research Fields	Others
Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .

HY-N0779A

Silybin 3 Publications Verification Silibinin	Structural Classification Classification of Application Fields Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Flavanonols Flavonoids Glycine soya Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Apoptosis
Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N0017

Bergenin 4 Publications Verification Cuscutin	Bergenia purpurascens (Hook. f. et Thoms.) Engl. Infection Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Saxifragaceae Plants Inflammation/Immunology Disease Research Fields	NF-κB Autophagy Apoptosis Bacterial Fungal Virus Protease
Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties .

HY-N12706

Heilaohuguosu G	Structural Classification Source classification Lignans Phenylpropanoids Kadsura coccinea (Lem.) A. C. Smith Plants Schisandraceae	Endogenous Metabolite
Heilaohuguosu G (compound 7) is a cyclolignan with hepatoprotective activity. Heilaohuguosu G against APAP toxicity with cell survival rates at 10 μM of 45.7% in HepG-2 cells .

HY-118383

Agathisflavone	Structural Classification Flavonoids Flavones Source classification Araucariaceae Agathis robusta (C. Moore ex F. Muell.) F. M. Bailey Plants	Parasite
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats .

HY-N3646

Cudratricusxanthone A	Structural Classification Flavonoids Source classification Maclura tricuspidata Carriere Plants Moraceae Other Flavonoids	Others
Cudratricusxanthone A is isolated from Cudrania tricuspidata, and has anti-inflammatory, hepatoprotective, and anti-proliferative activities. Cudratricusxanthone A inhibits osteoclast differentiation and function in RAW 264.7 cells and mouse bone marrow monocytes .

HY-N0222

Avicularin 4 Publications Verification	Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Plants Lauraceae Lindera aggregata (Sims) Kosterm. Inflammation/Immunology Disease Research Fields	COX NF-κB PPAR ERK GLUT Apoptosis
Avicularin is an orally active flavonoid. Avicularin inhibits NF-κB (p65), COX-2 and PPAR-γ activities. Avicularin has anti-inflammatory, anti-infectious anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities .

HY-N2094

Genipin 1-β-D-gentiobioside 1 Publications Verification Genipin 1-gentiobioside; Genipin 1-β-gentiobioside; Genipin gentiobioside	Structural Classification Iridoids Classification of Application Fields Terpenoids Source classification Rubiaceae Plants Gardenia jasminoides Ellis Inflammation/Immunology Disease Research Fields	Others
Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.

HY-N0344R

Farrerol (Standard)	Structural Classification Monophenols Flavonoids Rhododendron dauricum Linn. Flavonones Source classification Phenols Ericaceae Plants	Akt ERK JNK NF-κB
Farrerol (Standard) is the analytical standard of Farrerol. This product is intended for research and analytical applications. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .

HY-N4113

Glycycoumarin	Structural Classification Classification of Application Fields Leguminosae Source classification Coumarins Phenols Polyphenols Phenylpropanoids Plants Glycyrrhiza uralensis Fisch. Disease Research Fields Cancer	Keap1-Nrf2 AMPK
Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

HY-N2000

Bellidifolin	Infection Structural Classification Xanthones Classification of Application Fields Source classification Swertia bimaculata (Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark Gentianaceae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	HIV
Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities . Bellidifolin also acts as a viral protein R (Vpr) inhibitor .

HY-N9966

Sanggenol O	Structural Classification Flavonoids Flavonones Source classification Morus alba L. Plants Moraceae	Others
Sanggenol O? is an active product that can be extracted from Morus alba. Sanggenol O? has hepatoprotective and neuroprotective activities with EC₅₀s more than 80 μM in HepG2 and HT22 cells .

HY-125129

Carlinoside	Structural Classification Flavonoids Classification of Application Fields Flavones Cymbopogon citratus Gramineae Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Keap1-Nrf2
Carlinoside is a flavone glycoside with hepatoprotective efficiency. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Carlinoside has the potential to intervene hyperbilirubinemia due to liver dysfunction .

HY-N0691

Schisandrin 3 Publications Verification Schizandrin; Schizandrol; Schizandrol-A	Structural Classification Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields Cancer	Autophagy
Schisandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schisandrin exhibits antioxidant, hepatoprotective, anti-cancer and anti-inflammatory activities. Schisandrin also can reverses memory impairment in rats .

HY-N1521

Rehmannic acid Lantadene A	Triterpenes Classification of Application Fields Terpenoids Verbenaceae Source classification Plants Disease Research Fields Inflammation/Immunology Lantana camaraLinn.	Others
Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent .

HY-N9096

Gentiside B	Structural Classification Gentiana rigescens Franch. ex Hemsl. Source classification Gentianaceae Phenols Polyphenols Plants	Bacterial
Gentiside B has neuritogenic activity and induce neurite outgrowth. Gentiside B can be isolated from the root and rhizome of Gentiana rigescens. Gentiana has hepatoprotective, anti-inflammatory, analgesic, antiproliferative and antimicrobial effects .

HY-N0823

Lithospermic acid 3 Publications Verification (+)-Lithospermic acid	Structural Classification Classification of Application Fields Labiatae Samanea saman (Jacq.) Merr. Source classification Other Phenylpropanoids Phenols Polyphenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	NO Synthase AMPK Keap1-Nrf2 Xanthine Oxidase Apoptosis
Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl₄)-induced acute liver damage in vitro and in vivo .

HY-N1214R

Squalene (Standard)	Triterpenes Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Animals Terpenoids Source classification Plants Endogenous metabolite	Endogenous Metabolite Reactive Oxygen Species Fungal
Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-W068771

(E)-3-(4-Methoxyphenyl)acrylic acid	Structural Classification other families Simple Phenylpropanols Source classification Phenylpropanoids Plants	Endogenous Metabolite
(E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities .

HY-N2412

Irisolidone	Structural Classification Neurological Disease Classification of Application Fields Source classification Pueraria lobata (Willd.) Ohwi var. montana (Lour.)van der Maesen Plants Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Isoflavones Cancer	Chloride Channel
Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC₅₀=9.8 μM) .

HY-N0017R

Bergenin (Standard)	Bergenia purpurascens (Hook. f. et Thoms.) Engl. Structural Classification Source classification Phenols Polyphenols Saxifragaceae Plants	NF-κB Autophagy Apoptosis Bacterial Fungal Virus Protease
Bergenin (Standard) is the analytical standard of Bergenin. This product is intended for research and analytical applications. Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties .

HY-N7543

Schisantherin D	Infection Schisandra sphenanthera Rehd. et Wils Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields	HIV
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC₅₀ of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects .

HY-N0779AR

Silybin (Standard)	Flavanonols Structural Classification Flavonoids Glycine soya Source classification Phenols Polyphenols Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Apoptosis
Silybin (Standard) is the analytical standard of Silybin. This product is intended for research and analytical applications. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N0526

2"-O-Galloylhyperin	Flavonols Structural Classification Classification of Application Fields Source classification Plants Flavonoids Pyrola calliantha H. Andr. Pyrolaceae Phenols Polyphenols Pyrola incarnata Fisch. ex DC. Inflammation/Immunology Disease Research Fields	Others
2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage .

HY-N0692

Schisandrol B 2 Publications Verification Gomisin-A; TJN-101; Wuweizi alcohol-B	Structural Classification Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields Cancer	Reactive Oxygen Species Cytochrome P450 Autophagy
Schisandrol B (Gomisin-A) is a major active constituent of Schisandra chinensis with hepato-protective effects. Schisandrol B inhibits reactive oxygen species (ROS) production. Schisandrol B inhibits the activity of P-glycoprotein and CYP3A and also has anti-inflammatory, anti-diabetic and antioxidant activities .

HY-N10755A

(±)-ε-Viniferin	Structural Classification Paeonia lactiflora Pall. Source classification Phenols Polyphenols Plants Paeoniaceae	Cytochrome P450 Bacterial
(±)-ε-Viniferin is a racemate of ε-Viniferin (HY-N3841). (±)-ε-Viniferin exhibits P450 inhibitory antioxidants, as well as hepato-protective and antimicrobial activities. (±)-ε-Viniferin has antibacterial and antibiofilm activity against Gram-positive bacteria Streptococcus pneumoniae with a MIC of 20 μM .

HY-N0222R

Avicularin (Standard)	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Plants Lauraceae Lindera aggregata (Sims) Kosterm. Inflammation/Immunology Disease Research Fields	COX NF-κB PPAR ERK GLUT Apoptosis
Avicularin (Standard) is the analytical standard of Avicularin. This product is intended for research and analytical applications. Avicularin is an orally active flavonoid. Avicularin inhibits NF-κB (p65), COX-2 and PPAR-γ activities. Avicularin has anti-inflammatory, anti-infectious anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities .

Cat. No.	Product Name	Chemical Structure

HY-152052S

Linalool-d5

Linalool-d₅ is the deuterium labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-N1214S

Squalene-d6
Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-N0368S1

Linalool-13C3

Linalool- ¹³C₃ is ¹³C labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-N0368S2

Linalool-d6

Linalool-d₆ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-N0055S

Chlorogenic acid-13C3

Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

HY-W010410S

Oct-1-en-3-ol-d3

Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

Cat. No.	Product Name		Classification

HY-W010800

Cholesteryl hemisuccinate		Cholesterol
Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth .

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