Search Result
Results for "
fluoro
" in MedChemExpress (MCE) Product Catalog:
42
Biochemical Assay Reagents
25
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W008186
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fluorohydroxybenzoicacid
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Biochemical Assay Reagents
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Others
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4-Fluoro-2-hydroxybenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W021482
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- HY-122473
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SGLT
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Metabolic Disease
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fluoro-Dapagliflozin, a structural analog of Dapagliflozin, is a selective SGLT2 inhibitor with Ki values of 5.3 nM and 330 nM for SGLT2 and SGLT1, respectively. fluoro-Dapagliflozin blocks glucose transport and glucose-coupled currents .
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- HY-CE00554
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- HY-168358
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Drug Derivative
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Others
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4'-Fluoro diazepam is a 1,4-benzodiazepine compound. 4'-Fluoro diazepam is structurally similar to Diazepam, but its has only minimal biological activity .
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- HY-139359
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- HY-170054
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p-fluoro 4-ANBP; Despropionyl N-benzyl p-fluoro norfentanyl
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Drug Intermediate
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Neurological Disease
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Para-fluoro 4-ANBP (p-Fluoro 4-ANBP) is a precursor in the synthesis of Fluoroketamine.
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- HY-172062
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- HY-170055
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m-fluoro 4-ANBP; Despropionyl N-benzyl m-fluoro norfentanyl
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Opioid Receptor
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Neurological Disease
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Meta-fluoro 4-ANBP (m-Fluoro 4-ANBP) is structurally similar to known opioids.
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- HY-116217R
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DNA Methyltransferase
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Cancer
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5-Fluoro-2'-deoxycytidine (Standard) is the analytical standard of 5-Fluoro-2'-deoxycytidine. This product is intended for research and analytical applications. 5-Fluoro-2'-deoxycytidine (FdCyd), a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective proagent of thymidylate synthase inhibitor 5-fluoro-2′-dUMP. 5-Fluoro-2'-deoxycytidine can induce cell cycle arrest in tumor cells through the DNA damage response, and it has anti-tumor activity .
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- HY-139370
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- HY-W002291
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4-fluoro-L-phenylalanine
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Biochemical Assay Reagents
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Others
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p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine specific receptor of Escherichia coli (KD=0.26 μM) .
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- HY-59289
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2-fluoro-6-methoxyphenylboronic acid
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Biochemical Assay Reagents
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Others
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2-Fluoro-6-methoxybenzeneboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007614
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3-fluoro-para-anisaldehyde
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Biochemical Assay Reagents
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Others
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3-Fluoro-4-methoxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W005085
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5-fluoro-O-Anisaldehyde
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Biochemical Assay Reagents
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Others
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5-Fluoro-2-methoxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-32914
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Biochemical Assay Reagents
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Others
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4-Fluoro-2-methylphenylboronic acid is an arylboronic acid. 4-Fluoro-2-methylphenylboronic acid can be used in synthesis of piperidone when reacting with 3,4-dihydropyridine-1(2H)-carboxylate .
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- HY-135030
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Drug Derivative
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Neurological Disease
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4-Fluoro BZP hydrochloride is a benzylpiperazines (BZP) derivative. Benzylpiperazines are stimulant agents which inhibit monoamine uptake.
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- HY-172058
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- HY-I0561
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5-Bromo-2-fluoro-benzaldehyde
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Biochemical Assay Reagents
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Others
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2-Fluoro-5-bromobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-160428
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- HY-172049
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- HY-172048
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- HY-172047
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- HY-44481
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Drug Intermediate
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Others
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3'-Fluoro-4'-methylacetanilide is a drug intermediate for synthesis of various active compounds.
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- HY-30051
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- HY-20138
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Drug Intermediate
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Others
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2-Fluoro-5-formylbenzonitrile is a drug intermediate for synthesis of various active compounds.
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- HY-41559
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Drug Intermediate
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Others
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2-Fluoro-5-formylbenzoic acid is a drug intermediate for synthesis of various active compounds.
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- HY-44532
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Drug Intermediate
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Others
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5-Fluoro-2-hydroxynicotinaldehyde is a drug intermediate for synthesis of various active compounds.
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- HY-172036
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- HY-W070813
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- HY-W008356
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Drug Intermediate
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Infection
Metabolic Disease
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2-Fluoro-4-iodobenzonitrile is a building block, which can be used to synthesize L. infantum trypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors. 2-Fluoro-4-iodo benzonitrile can also be used to synthesize transient receptor potential ankyrin 1 (TRPA1) antagonists .
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- HY-W744592
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- HY-W104076
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Drug Metabolite
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Others
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2-Amino-2'-fluoro-5-nitrobenzophenone is a precursor in the synthesis of benzodiazepines. 2-Amino-2'-fluoro-5-nitrobenzophenone is also an acid hydrolysis product of Flunitrazepam.
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- HY-W318448
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- HY-116217
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FdCyd; NSC-48006
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DNA Methyltransferase
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Cancer
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5-Fluoro-2'-deoxycytidine (FdCyd), a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective proagent of thymidylate synthase inhibitor 5-fluoro-2′-dUMP. 5-Fluoro-2'-deoxycytidine can induce cell cycle arrest in tumor cells through the DNA damage response, and it has anti-tumor activity .
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- HY-W616732
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- HY-172044
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- HY-172045
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- HY-158943
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- HY-155878A
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- HY-155878
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- HY-W1023070
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5-HT Receptor
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Neurological Disease
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4-fluoro MBZP is a new psychoactive substance that belongs to the phenylpiperazine class of compounds and can be used to study the 5-HT2 receptors in the central nervous system .
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- HY-W002914
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Biochemical Assay Reagents
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Others
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5-Fluoro-2-oxoindoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007531
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Biochemical Assay Reagents
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Others
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2-Fluoro-5-iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W008088
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Biochemical Assay Reagents
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Others
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4-Fluoro-3-nitrobenzonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-32923
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Biochemical Assay Reagents
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Others
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2-Fluoro-3-methoxyphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007428
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Biochemical Assay Reagents
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Others
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3-Fluoro-2-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-34656
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Biochemical Assay Reagents
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Others
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5-Fluoro-2-pyridinecarbonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W008187
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Biochemical Assay Reagents
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Others
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4-Fluoro-3-nitrobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-32924
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Biochemical Assay Reagents
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Others
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5-Fluoro-2-methoxyphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W008027
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Biochemical Assay Reagents
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Others
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3-Fluoro-4-formylphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-142907S
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- HY-W012392
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Biochemical Assay Reagents
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Others
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3-Fluoro-4-iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-139388
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- HY-W460227
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Ligands for E3 Ligase
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Cancer
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Lenalidomide-4-Br-7-fluoro is a derivative of Lenalidomide with a flouride and bromide groups on the benzyl ring.
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- HY-161501
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GLUT
Topoisomerase
Apoptosis
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Cancer
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3-Fluoro-evodiamine glucose (Compound 8) is an evodiamine-glucose conjugate. 3-Fluoro-evodiamine glucose activates the expression of glucose transporter 1 (GLUT1), and inhibits topoisomerase I/II. 3-Fluoro-evodiamine glucose induces apoptosis and arrests the cell cycle at G2/M phase. 3-Fluoro-evodiamine glucose exhibits antitumor efficacy in vivo and in vitro, without significant toxicity .
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- HY-W704668
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- HY-132160
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ADC Payload
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Cancer
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7-Aminomethyl-10-methyl-11-fluoro camptothecin is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158). 7-Aminomethyl-10-methyl-11-fluoro camptothecin can be used for the synthesis of camptothecin antibody-drug conjugate (ADC) .
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- HY-W011526
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- HY-172037
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- HY-172035
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- HY-W007613
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Biochemical Assay Reagents
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Others
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7-Fluoro-1H-indole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-32922
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Biochemical Assay Reagents
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Others
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(3-Fluoro-4-methoxyphenyl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W000994
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Biochemical Assay Reagents
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Others
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(3-Fluoro-2-formylphenyl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-P5372
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Protease Activated Receptor (PAR)
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Others
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Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biological active peptide. (Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This peptide is a PAR-1 selective agonist displaying a high level of specificity to PAR-1 over PAR-2. The specificity of peptide was evaluated in cell-based calcium signaling assay using HEK293 cells. PAR-1 selective agonists can be used to study PAR-1 activation in vivo. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.)
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- HY-CE00162
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(2S,3R)-3-fluoro-2-methylhexadecanoyl-coenzyme A
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Biochemical Assay Reagents
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Others
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(2S,3R)-3-Fluoro-2-methylhexadecanoyl-CoA ((2S,3R)-3-Fluoro-2-methylhexadecanoyl-coenzyme A) is a derivative of Coenzyme A (HY-128851).
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- HY-CE00001
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(2R,3S)-3-fluoro-2-methylhexadecanoyl-coenzyme A
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Biochemical Assay Reagents
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Others
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(2R,3S)-3-Fluoro-2-methylhexadecanoyl-CoA ((2R,3S)-3-Fluoro-2-methylhexadecanoyl-coenzyme A) is a derivative of Coenzyme A (HY-128851).
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- HY-W751668
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![B-[2-Fluoro-3-(methoxy-d3)phenyl]boronic Acid](//file.medchemexpress.eu/product_pic/hy-w751668.gif)
- HY-W012808S
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- HY-78863
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Drug Intermediate
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Others
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4-Fluoro-2-Methoxy-5-Nitroaniline is a drug intermediate for synthesis of various active compounds.
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- HY-65268
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Drug Intermediate
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Others
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4-Fluoro-5-hydroxy-2-methylindole is a drug intermediate for synthesis of various active compounds.
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- HY-77865
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Drug Intermediate
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Others
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4-Fluoro-5-isopropyl-2-methoxyphenylboronic acid is a drug intermediate for synthesis of various active compounds.
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- HY-23946
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Drug Intermediate
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Others
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5-Fluoro-2-methylpyridin-3-amine is a drug intermediate for synthesis of various active compounds.
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- HY-W016336
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- HY-132160A
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ADC Payload
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Cancer
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7-Aminomethyl-10-methyl-11-fluoro camptothecin TFA is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158). 7-Aminomethyl-10-methyl-11-fluoro camptothecin TFA can be used for the synthesis of camptothecin antibody-drug conjugate (ADC) .
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- HY-W768607
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- HY-34673
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o-Iodofluorobenzene
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Biochemical Assay Reagents
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Others
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1-Fluoro-2-iodobenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W743525
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- HY-W141942
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- HY-W009794
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- HY-66016
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Drug Intermediate
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Others
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3-[(2-Fluoro-4-iodophenyl)amino]isonicotinic acid is a drug intermediate for synthesis of various active compounds.
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![3-[(2-Fluoro-4-iodophenyl)amino]isonicotinic acid](//file.medchemexpress.eu/product_pic/hy-66016.gif)
- HY-W007161
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Bacterial
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Infection
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8-Desmethoxy-8-fluoro Moxifloxacin (Compound 07) is an antibacterial agent, and has bactericidal activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis .
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- HY-W015849S
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- HY-163210
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Ligands for E3 Ligase
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Cancer
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Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride (ZJT1) is an E3 ubiquitin ligase cereblon based on Pomalidomide (HY-10984) (CRBN) ligand for recruitment of cereblon protein. Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride can be linked to protein ligand by linker to form PROTAC .
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- HY-172043
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- HY-172032
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- HY-152298
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Nucleoside Antimetabolite/Analog
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Others
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5-Fluoro-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-79295
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N-BOC-3-fluoro-D-phenylalanine; N-tert-Butoxycarbonyl-3-fluoro-D-phenylalanine
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Amino Acid Derivatives
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Others
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N-BOC-3-Fluoro-D-phenylalanine is a phenylalanine derivative .
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- HY-D0111
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4-fluorobenzofurazan
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Fluorescent Dye
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Others
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4-Fluoro-2,1,3-benzoxadiazol (4-Fluorobenzofurazan) is a fluorescent benzofurazan derivative .
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- HY-77021
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- HY-152522
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Nucleoside Antimetabolite/Analog
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Others
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5-Fluoro-4’-C-methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
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- HY-152526
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Nucleoside Antimetabolite/Analog
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Others
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5-Fluoro-4’-C-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-21045
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L-5-fluorotryptophan
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EAAT
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Neurological Disease
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5-Fluoro-L-tryptophan is a competitive vesicular glutamate transporter (VGLUT) inhibitor. 5-Fluoro-L-tryptophan is promising for research of diseases associated with the neurotransmitter systems .
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- HY-114553
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5F-PB-22 3-carboxyindole metabolite
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Cannabinoid Receptor
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Neurological Disease
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5-Fluoro PB-22 3-carboxyindole metabolite (5F-PB-22 3-carboxyindole metabolite) is a metabolite of 5-fluoro PB-22. 5-Fluoro PB-22 is a synthetic cannabinoid .
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- HY-W074978
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3-fluorovaline
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Bacterial
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3-Fluoro-DL-valine (3-Fluorovaline) is an unnatural amino acid that has the activity of inhibiting the growth of certain bacteria. 3-Fluoro-DL-valine can also be used in peptide synthesis, providing a variety of options for the synthesis of specific bioactive peptides. The unique structure of 3-Fluoro-DL-valine makes it a potential application prospect in compound research and development.
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- HY-43552
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Drug Intermediate
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Others
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2-Amino-6-fluoro-4-(2-methoxyethoxy)benzonitrile is a drug intermediate for synthesis of various active compounds.
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- HY-W042139
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Drug Intermediate
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Others
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Methyl 6-fluoro-1H-indole-4-carboxylate is a drug intermediate for synthesis of various active compounds.
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- HY-W288676
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Biochemical Assay Reagents
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Others
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6-Fluoro-3-indolyl-β-D-galactopyranoside is a chromogenic enzyme substrate commonly used in microbiology to detect the expression of β-galactosidase in bacterial colonies.
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- HY-152640
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Nucleoside Antimetabolite/Analog
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Cancer
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5-Fluoro-4’-thio-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W002924
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Biochemical Assay Reagents
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Others
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6-Chloro-2-fluoro-9H-purine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W104477
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Others
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Metabolic Disease
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3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association .
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- HY-77026
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- HY-I0124
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- HY-D0102
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ABD-F
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Fluorescent Dye
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Others
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4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent for the sensitive and specific detection of thiols. 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole has low fluorescence background, and good stability of fluorophor .
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- HY-148167
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DNA/RNA Synthesis
Virus Protease
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Infection
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2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication .
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- HY-W681014
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5-HT Receptor
Dopamine Receptor
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Neurological Disease
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5-Fluoro-α-methyltryptamine hydrochloride may cause an increase in intracellular levels of 5-HT followed by an increase in 5-HT release. 5-Fluoro-α-methyltryptamine hydrochloride exhibits EC50 values of 37 nM, 14 nM, 78 nM and 8.47 nM for DA, 5HT, NE and 5-HT2A, respectively .
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- HY-23660
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Drug Intermediate
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Others
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5-Fluoro-2-(1H-pyrrol-1-yl)aniline is a drug intermediate for synthesis of various active compounds.
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- HY-157386S
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- HY-141637S
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- HY-146990S
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- HY-152763
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Nucleoside Antimetabolite/Analog
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Others
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2’-Deoxy-2’-fluoro-5-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-77151
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- HY-118583A
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β-(4-fluorophenyl)-GABA hydrochloride; F-Phenibut hydrochloride
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Drug Derivative
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Neurological Disease
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4-Fluoro phenibut (β-(4-Fluorophenyl)-GABA) hydrochloride is a Gabapentinoid and is structurally similar to known nootropics .
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- HY-I0125
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- HY-155869
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5-fluoro-2′-deoxycytidine 5′-triphosphate
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DNA/RNA Synthesis
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Others
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5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
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- HY-155869A
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5-fluoro-2′-deoxycytidine 5′-triphosphate sodium
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DNA/RNA Synthesis
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Others
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5-fluoro-dCTP sodium is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
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- HY-154136
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Nucleoside Antimetabolite/Analog
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Cancer
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5-Fluoro-3’-beta-C-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-D0785
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4-fluoro-7-nitrobenzofurazan
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Fluorescent Dye
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Others
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NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent which is developed for amino acid analysis. NBD-F reacts with primary or secondary amines to produce a fluorescent product and used for analysis of amino acids and low molecular weight amines .
|
-
- HY-152612
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-5-hydroxymethyl arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-W001260S
-
|
4-Cyano-2-fluorobenzyl alcohol-d2
|
Isotope-Labeled Compounds
|
Others
|
|
3-Fluoro-4-(hydroxymethyl)benzonitrile-d2 is the deuterium labeled 3-Fluoro-4-(hydroxymethyl)benzonitrile (HY-W001260).
|
-
- HY-128710
-
|
2'-Deoxy-2'-fluoro-5-Methyluridine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2) .
|
-
- HY-78467S
-
-
- HY-152820
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-152757
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152754
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152753
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152760
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W539754
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'-Deoxy-2'-fluoro-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152302
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-3’-fluoro-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152761
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-5-methoxyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152329
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152674
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2′-Deoxy-2′-fluoro-5-methoxy-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-W768211
-
-
- HY-152811
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-42121
-
|
4-Bromo-2-fluoroiodobenzene
|
Biochemical Assay Reagents
|
Others
|
|
4-Bromo-2-fluoro-1-iodobenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W342664
-
|
FIRU
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-Deoxy-2'-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-116705
-
|
|
Glycosyltransferase
|
Cancer
|
|
2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma .
|
-
- HY-152813
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2′-Deoxy-2′-fluoro-4-deoxy-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152489
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Chloro-2’-deoxy-2’-fluoro inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154531
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′,3′-Dideoxy-3′-fluoro-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154203
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
4-Deoxy-3’-deoxy-3’-fluoro uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152815
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2′-Deoxy-2′-fluoro-3-deaza-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152390
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-45409
-
|
2'-F-dU Phosphoramidite
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA .
|
-
- HY-125150
-
-
- HY-48973
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-W089288
-
|
N6-Benzoyl-2'-fluoro-2'-deoxyadenosine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'-F-Bz-A (N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
|
-
- HY-154246
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152736
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-141637
-
|
2-fluoro-2-deoxy-D-glucose; 2-Deoxy-2-fluoro-D-glucopyranose
|
Biochemical Assay Reagents
|
Others
|
|
2-Deoxy-2-fluoro-D-glucose, a radiolabeled glucose analog, is commonly used in medical imaging techniques such as positron emission tomography (PET) scans. FDG has unique chemical properties that allow it to be taken up by cells that actively metabolize glucose, such as cancer cells or inflamed tissue. Once absorbed, FDG emits positrons that can be detected in 2-Deoxy-2-fluoro-D-glucose scans, producing images that highlight areas of high metabolic activity in the body. This makes it a useful tool for diagnosing and monitoring a variety of diseases, including cancer and neurological disorders.
|
-
- HY-154037
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-3'-fluoro-2',3'-dideoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154605
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-iso-Butyroyl-2’-fluoro-2’-deoxyarabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154414
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-W334680
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin](//file.medchemexpress.eu/product_pic/hy-w334680.gif)
- HY-154612
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-4’-thio-a-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W382140
-
|
|
HCV
|
Infection
|
|
4′-C-Fluoro-2′-C-methyluridine is a nucleotide analog, which exhibits antiviral activity against hepatitis C virus (HCV) .
|
-
- HY-152350
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-4’-thio-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152527
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W599086
-
|
|
Drug Intermediate
|
Others
|
|
3-((tert-Butoxycarbonyl)amino)-7-fluoro-8-((triisopropylsilyl)ethynyl)naphthalen-1-yl trifluoromethanesulfonate is a drug intermediate for synthesis of various active compounds.
|
-
- HY-152392
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Fluoro-2’-deoxy-N6,N6-dimethylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154463
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-iso-Butyroyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154321
-
-
- HY-W072701
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-43553
-
|
|
Drug Intermediate
|
Others
|
|
tert-Butyl (4-((5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl)amino)phenyl)carbamate is a drug intermediate for synthesis of various active compounds.
|
-
- HY-154608
-
|
|
DNA/RNA Synthesis
|
Others
|
|
3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluoro uridine-2’-CED-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-154362A
-
-
- HY-W046071
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-trans-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-154352
-
-
- HY-154236
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-21997
-
|
|
DNA/RNA Synthesis
Drug Intermediate
|
Others
|
|
DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity .
|
-
- HY-W068075A
-
|
|
Drug Intermediate
|
Others
|
|
(S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethanamine dihydrochloride is a drug intermediate for synthesis of various active compounds.
|
-
- HY-B1516
-
|
3'-fluoro-3'-deoxythymidine; 3′-Deoxy-3′-fluorothymidine; FLT
|
DNA/RNA Synthesis
Orthopoxvirus
|
Infection
Cancer
|
|
Alovudine (3'-Fluoro-3'-deoxythymidine) is a mtDNA synthesis inhibitor and a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus and anti-leukemic activity .
|
-
- HY-152364
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154779R
-
|
|
Nucleoside Antimetabolite/Analog
Reference Standards
|
Cancer
|
|
5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine (Standard) is the analytical standard of 5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine. This product is intended for research and analytical applications. 5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine (Standard)](//file.medchemexpress.eu/product_pic/hy-154779r.gif)
- HY-169440
-
|
6-F-DET
|
5-HT Receptor
|
Others
|
|
6-Fluoro-N,N-diethyltryptamine (6-F-DET) has affinity for 5-HT2A receptors .
|
-
- HY-W008147
-
|
|
Drug Intermediate
|
Others
|
|
3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a drug intermediate for synthesis of various active compounds.
|
-
- HY-W076405
-
|
|
Drug Intermediate
|
Others
|
|
3-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is a drug intermediate for synthesis of various active compounds.
|
-
- HY-43489
-
|
|
Drug Intermediate
|
Others
|
|
5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl acetate is a drug intermediate for synthesis of various active compounds.
|
-
- HY-141637S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-Deoxy-2-fluoro-D-glucose- 13C,d7 is the 13C-labeled and deuterium labeled 2-Deoxy-2-fluoro-D-glucose (HY-141637) . 2-Deoxy-2-fluoro-D-glucose, a radiolabeled glucose analog, is commonly used in medical imaging techniques such as positron emission tomography (PET) scans. FDG has unique chemical properties that allow it to be taken up by cells that actively metabolize glucose, such as cancer cells or inflamed tissue. Once absorbed, FDG emits positrons that can be detected in 2-Deoxy-2-fluoro-D-glucose scans, producing images that highlight areas of high metabolic activity in the body. This makes it a useful tool for diagnosing and monitoring a variety of diseases, including cancer and neurological disorders.
|
-
- HY-134554
-
|
|
Drug Derivative
|
Cancer
|
|
5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is an impurity in the synthesis of Capecitabine (HY-B0016) .
|
-
- HY-W003222
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-tert-Boc-cis-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-134033A
-
|
2'-fluoro dATP
|
DNA/RNA Synthesis
Drug Derivative
|
Infection
|
|
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium (2'-fluoro dATP) is a fluorinated derivative of ATP (HY-B2176). 2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium is a substrate and an inhibitor for E.coli DNA-dependent RNA polymerase, with a Ki of 200 µM .
|
-
- HY-152759
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-xylocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152584
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-xyloguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152554
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-xyloadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W555583
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152532
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152605
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-arabino-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W017749
-
-
- HY-154409
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-W854371
-
|
|
Biochemical Assay Reagents
|
Others
|
|
D-Arabinofuranose,2-deoxy-2-fluoro,1,3,5-triacetateis a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-154611
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W061614
-
|
|
Amino Acid Derivatives
|
Others
|
|
(4R)-1-Boc-4-fluoro-D-proline is an amino acid derivative that can be used for preparation of peptidomimetics, dihydropyridopyrimidines and pyridopyrimidines .
|
-
- HY-152348
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154315
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154316
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-3-Deaza-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154312
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3,5-Di-O-benzoyl-2-deoxy-2-fluoro-5-trifluoromethyl-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W416378S
-
|
N,N-Diisopropyl-4-fluorobenzamide-d4
|
Isotope-Labeled Compounds
|
Others
|
|
4-Fluoro-N,N-diisopropylbenzamide-d4 (N,N-Diisopropyl-4-fluorobenzamide-d4) is the deuterium labeled 4-Fluoro-N,N-diisopropylbenzamide (HY-W416378) .
|
-
- HY-148019
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-Deoxy-2′-fluoro-N-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154296
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-ara-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-42565
-
|
|
Drug Intermediate
|
Others
|
|
(2R,3S)-2-(4-(Cyclopentylamino)phenyl)-1-(2-fluoro-6-methylbenzoyl)piperidine-3-carboxylic acid is a drug intermediate for synthesis of various active compounds.
|
-
- HY-154459
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-2’-deoxy-5’-O-DMTr-2’-fluoro- 5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-I0622
-
|
((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate
|
Drug Intermediate
|
Others
|
|
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine (((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate) is a drug intermediate for synthesis of various active compounds.
|
-
- HY-20133
-
|
|
Drug Intermediate
|
Others
|
|
4-((2-Cyanopropan-2-yl)amino)-2-fluoro-N-methylbenzamide is a drug intermediate for synthesis of various active compounds.
|
-
- HY-W113972
-
|
2′-Deoxy-2′-fluoro-N-isobutyrylguanosine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'-F-iBu-G (2′-Deoxy-2′-fluoro-N-isobutyrylguanosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
|
-
- HY-132158
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin antibody-drug conjugate (ADC) .
|
-
- HY-W092426
-
|
|
Drug Intermediate
|
Others
|
|
2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a drug intermediate for synthesis of various active compounds.
|
-
- HY-115738
-
-
- HY-W128788A
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-b-D-arabinocytidine(hydrochloride) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-78066
-
|
6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
|
Drug Intermediate
|
Others
|
|
Abemaciclib Impurity 1 (6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole) is a drug intermediate for synthesis of various active compounds.
|
-
- HY-154078
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154726
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro- N3-(2S)-(2-amino-3-carbonyl)-propyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154071
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154083
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154072
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154447
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154231
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W141392
-
|
|
Nucleoside Antimetabolite/Analog
Xanthine Oxidase
|
Cancer
|
|
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
-
- HY-152504
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N1-methyladensoine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154291
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-3’-fluoro-N1-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154133
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-3’-fluoro-xylo-5-methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152340
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Amino-2’-deoxy-5-fluoro-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154295
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N1-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152301
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-N6-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152403
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-3’-fluoro-xylo-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154134
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-3’-fluoro-xylo-5-trifluoromethyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W355280
-
|
|
Biochemical Assay Reagents
|
Others
|
|
α-D-Glucopyranoside,methyl 4-deoxy-4-fluoro,2,3,6-tribenzoate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-154185
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-methyl-β-D-arabino-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W415930
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-Deoxy-3-fluoro-D-galactose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W415934
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Deoxy-4-fluoro-D-mannose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W357096
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Deoxy-4-fluoro-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W415931
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-Deoxy-3-fluoro-D-mannose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W743751
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Deoxy-2-fluoro-D-galactose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W285163S
-
|
Formyl Ciprofloxacin-d8
|
Isotope-Labeled Compounds
|
Others
|
|
1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-d8 is deuterated labeled 1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid.
|
-
- HY-W038588
-
|
|
Drug Intermediate
|
Others
|
|
2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-en-1-one is a drug intermediate for synthesis of various active compounds.
|
-
- HY-152457
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-3’-fluoro-beta-D-xylo-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-44072
-
|
|
Drug Intermediate
|
Others
|
|
7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4-dione is a drug intermediate for synthesis of various active compounds.
|
-
![7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4-dione](//file.medchemexpress.eu/product_pic/hy-44072.gif)
- HY-152782
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W009538
-
|
5-fluoro-5'-deoxycytidine
|
Nucleoside Antimetabolite/Analog
DNA/RNA Synthesis
Drug Metabolite
|
Cancer
|
|
5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
|
-
- HY-152634
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152492
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N1-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W128788
-
|
4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-b-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152585
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-152597
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-154362
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-45492
-
|
2'-F-ibu-dG Phosphoramidite
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine .
|
-
- HY-152705
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
5-Bromo-2’-deoxy-2’-fluoro-beta-D-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-112120
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine ((2R,3S,4S,5R)-2-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W096852
-
|
|
Drug Intermediate
|
Others
|
|
((2-Fluoro-6-(methoxymethoxy)-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-yl)ethynyl)triisopropylsilane is a drug intermediate for synthesis of various active compounds.
|
-
- HY-W699426
-
|
|
Biochemical Assay Reagents
|
Others
|
|
D-Galactopyranose,4-deoxy-4-fluoro,tetraacetate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-152880
-
|
T 70179
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-arabino-tubercidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-23171
-
-
- HY-48671
-
|
|
Drug Intermediate
|
Others
|
|
((6-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-((triisopropylsilyl)ethynyl)naphthalen-2-yl)oxy)triisopropylsilane is a drug intermediate for synthesis of various active compounds.
|
-
- HY-154779
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine](//file.medchemexpress.eu/product_pic/hy-154779.gif)
- HY-152769
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2-Methoxy-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152378
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152864
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
6-Methylpurine-2’-deoxy-2’-fluoro-beta-D-arabinoriboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152349
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-β-D-arabino-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154680
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154727
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N3-(3-aminopropyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154682
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154489
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154723
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N3-(4-hydroxybenzyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154410
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-152374
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3’-Deoxy-3’-fluoro-N6,N6-dimethyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-49198
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152987
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .
|
-
![7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine](//file.medchemexpress.eu/product_pic/hy-152987.gif)
- HY-W739643
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Methyl 4-deoxy-4-fluoro-α-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W599085
-
|
|
Drug Intermediate
|
Others
|
|
tert-Butyl (6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-((triisopropylsilyl)ethynyl)naphthalen-2-yl)carbamate is a drug intermediate for synthesis of various active compounds.
|
-
- HY-152661
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152404
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-3’-fluoro-xylo-N6-(m-methoxybenzyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154412
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152762
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154135
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-Deoxy-3’-fluoro-xylo-N6-(p-methoxybenzyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152691
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-152310
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N4-(n-Palmitoyl)-4’-azido-2’-deoxy-2’-fluoro-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities . N4-(n-Palmitoyl)-4’-azido-2’-deoxy-2’-fluoro-arabinocytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-152792
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]uridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
![2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]uridine](//file.medchemexpress.eu/product_pic/hy-152792.gif)
- HY-152785
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154725
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![2’-Deoxy-2’-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine](//file.medchemexpress.eu/product_pic/hy-154725.gif)
- HY-152689
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152780
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W096600
-
|
1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos
|
Glycosyltransferase
|
Cancer
|
|
2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) acts as a potent fucosyltransferase (FUT) inhibitor .
|
-
- HY-152373
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154681
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N3-[(pyrid-4-yl)methyl]uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![2’-Deoxy-2’-fluoro-N3-[(pyrid-4-yl)methyl]uridine](//file.medchemexpress.eu/product_pic/hy-154681.gif)
- HY-152695
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W009538R
-
|
5-fluoro-5'-deoxycytidine (Standard)
|
Nucleoside Antimetabolite/Analog
Reference Standards
DNA/RNA Synthesis
Drug Metabolite
|
Cancer
|
|
5'-Deoxy-5-fluorocytidine (Standard) is the analytical standard of 5'-Deoxy-5-fluorocytidine (HY-W009538). This product is intended for research and analytical applications. 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
|
-
- HY-154683
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154583
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’,5’-Bis-O-benzoyl-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154555
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152766
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
6-(Thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152460
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Chloro-N6-cyclopentyl-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W699259
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Phenylmethyl 2-(acetylamino)-2,4-dideoxy-4-fluoro-α-D-glucopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-152772
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2-Amino-6-chloropurine-9-beta-D-(2’-deoxy-2’-fluoro)-arabinoriboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152690
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]-beta-D-arabinouridine](//file.medchemexpress.eu/product_pic/hy-152690.gif)
- HY-152734
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152809
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152727
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154658
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N3-[(pyrid-4-yl)methyl]-beta-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![2’-Deoxy-2’-fluoro-N3-[(pyrid-4-yl)methyl]-beta-D-arabinouridine](//file.medchemexpress.eu/product_pic/hy-154658.gif)
- HY-154643
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152776
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152791
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-methyl-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-147080
-
|
ARC1905
|
Complement System
|
Others
|
|
Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system. Avacincaptad pegol sodium treats Geographic atrophy (GA) mice .
|
-
- HY-148457
-
|
|
Complement System
|
Infection
Inflammation/Immunology
|
|
Avacincaptad pegol, which is a pegylated aptamer, has garnered significant attention as a C5 complement inhibitor that may reduce inflammation-related retinal pigment epithelium (RPE) damage. Avacincaptad pegol caqn be used for the research of stargardt macular dystrophy (STGD1) and geographic atrophy (GA) .
|
-
- HY-132587
-
|
ALN-AT3SC; SAR439774
|
Small Interfering RNA (siRNA)
Factor Xa
|
Others
|
|
Fitusiran (ALN-AT3SC), an small interfering RNA, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. Fitusiran increases thrombin generation and has the potential for the research of the hemophilia .
|
-
- HY-154604
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-147278
-
-
- HY-145720
-
-
- HY-109561
-
|
EYE001; NX1838
|
VEGFR
|
Metabolic Disease
Inflammation/Immunology
|
|
Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) .
|
-
- HY-132610
-
|
ALN-AS1
|
Small Interfering RNA (siRNA)
|
Neurological Disease
|
|
Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid and porphobilinogen levels. Givosiran can be used for the research of acute intermittent porphyria .
|
-
- HY-154618
-
|
|
DNA/RNA Synthesis
|
Others
|
|
N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-3’-deoxy-3’-fluoro-beta-D-xylofuranosyl cytidine-2’-CED-phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-132602
-
|
MRG-201
|
MicroRNA
|
Inflammation/Immunology
|
|
Remlarsen (MRG-201), a miR-29b mimic, acts a miR-29b agonist. Remlarsen has the potential for preventiong formation of a fibrotic scar or cutaneous fibrosis .
|
-
- HY-154733
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
![9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine](//file.medchemexpress.eu/product_pic/hy-154733.gif)
- HY-147425
-
-
- HY-132591
-
-
- HY-152709
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154118
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabino-6-azidouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154676
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Purine-9-b-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-132604
-
|
ARO-AAT
|
Small Interfering RNA (siRNA)
|
Metabolic Disease
|
|
Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease.
|
-
- HY-132613
-
|
|
Small Interfering RNA (siRNA)
|
Metabolic Disease
|
|
Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) .
|
-
- HY-132588
-
|
ALN-G01
|
Small Interfering RNA (siRNA)
|
Metabolic Disease
|
|
Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1) .
|
-
- HY-154679
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152788
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W009538S
-
|
5-fluoro-5'-deoxycytidine-d3
|
Nucleoside Antimetabolite/Analog
Isotope-Labeled Compounds
DNA/RNA Synthesis
Drug Metabolite
|
Cancer
|
|
5'-Deoxy-5-fluorocytidine-d3 is deuterated labeled 5'-Deoxy-5-fluorocytidine (HY-W009538). 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
|
-
- HY-154335
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-132589
-
-
- HY-152485
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Amino-N6,N6-dimethyl-2’-deoxy-2’-fluoro-beta-D-arabino-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154675
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Aminopurine-9-beta-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152686
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154678
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-152676
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-152687
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl) pyridin-3-yl]purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl) pyridin-3-yl]purine](//file.medchemexpress.eu/product_pic/hy-152687.gif)
- HY-152704
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine](//file.medchemexpress.eu/product_pic/hy-152704.gif)
- HY-154662
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![2’-Deoxy-2’-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine](//file.medchemexpress.eu/product_pic/hy-154662.gif)
- HY-154724
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoro-N3-(2S)-[2-(tert-butoxy-carbonyl)-amino-3-carbonyl]propyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
![2’-Deoxy-2’-fluoro-N3-(2S)-[2-(tert-butoxy-carbonyl)-amino-3-carbonyl]propyluridine](//file.medchemexpress.eu/product_pic/hy-154724.gif)
- HY-152773
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-W605935
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2-Amino-6-chloropurine -9-beta-D-(2’-deoxy-3’,5’-di-O-benzoyl-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W699260
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Benzyl 2-acetamido-3,6-di-O-benzoyl-2,4-dideoxy-4-fluoro-α-D-glucopyranose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-Glycan recognition and the role of glycans in biological systems. This field is closely related to basic research, biomedicine and biotechnology.
|
-
- HY-W020420
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
6-Chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W550484
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2,6-Dichloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl)-9H-purine arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-48099
-
|
|
Drug Intermediate
|
Others
|
|
tert-Butyl (S)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-3-(2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate is a drug intermediate for synthesis of various active compounds.
|
-
![tert-Butyl (S)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-3-(2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate](//file.medchemexpress.eu/product_pic/hy-48099.gif)
- HY-W009538S1
-
|
5-fluoro-5'-deoxycytidine-13C5
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Drug Metabolite
|
Cancer
|
|
5'-Deoxy-5-fluorocytidine-13C5 is the 13C labeled isotope of 5'-Deoxy-5-fluorocytidine (HY-W009538). 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
|
-
- HY-77931
-
|
VX-661 intermediate
|
Drug Intermediate
|
Others
|
|
(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol (VX-661 intermediate) is a drug intermediate for synthesis of various active compounds.
|
-
![(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol](//file.medchemexpress.eu/product_pic/hy-77931.gif)
- HY-Y0680
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Fluoro-3-chloroaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W001028
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-Fluoro-2-formylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007331
-
|
|
Biochemical Assay Reagents
|
Others
|
|
5-Fluoro-2-hydroxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-169803
-
|
|
Prostaglandin Receptor
|
Cardiovascular Disease
|
|
L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, composed of (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-l-yl acetic acid. The IC50s of (-) and (+) configurations for TxA2 are 0.27 nM and 124 nM, respectively.
|
-
- HY-P2496
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB .
|
-
- HY-W377455
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (2',5-difluoro-2'-deoxy-1-arabinosyluracil) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-W013775S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid-d8 hydrochloride is the deuterium labeled 9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride .
|
-
- HY-W114781
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-(4-Fluorophenyl)-N-methylmethanamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-100705
-
|
6-Nitroveratraldehyde
|
Drug Intermediate
|
Neurological Disease
|
|
DMNB (6-Nitroveratraldehyde), a precursor, can be used for the synthesis no-carrier-added 6-[ 18F]fluoro-L-DOPA (6-FDOPA). No-Carrier-Added (NCA) 6-[18F]fluoro-L-dopa (6-FDOPA) is being produced routinely for PET investigations of dopaminergic systems .
|
-
- HY-128710R
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-Fluorothymidine (Standard) is the analytical standard of 2'-Fluorothymidine. This product is intended for research and analytical applications. 2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2) .
|
-
- HY-159045
-
|
p-fluoro-SAHA
|
HDAC
|
Cancer
|
|
F-SAHA is a HDAC inhibitor (HDACi) and its 18F labeled derivative can be used in tumor imaging research .
|
-
- HY-W577257
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
5-Fluoro-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione is a fluorinated E3 ligase activator. Thalidomide-1-Me,5-F may be used for further derivitization by SNAr.
|
-
- HY-12807A
-
|
5-fluoro-2-indolyl deschlorohalopemide hydrochloride
|
Phospholipase
|
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
Cancer
|
|
FIPI hydrochloride is a phospholipase D (PLD) inhibitor with an IC50 for PLD1 and PLD2 of about 25 nM. FIPI hydrochloride regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI hydrochloride can be used in cancer research. In addition, FIPI hydrochloride can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function .
|
-
- HY-12807
-
FIPI
4 Publications Verification
5-fluoro-2-indolyl deschlorohalopemide
|
Phospholipase
|
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
Cancer
|
|
FIPI is a phospholipase D (PLD) inhibitor with an IC50 for PLD1 and PLD2 of about 25 nM. FIPI regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI can be used in cancer research. In addition, FIPI can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function .
|
-
- HY-106379
-
|
GR-87442
|
5-HT Receptor
|
Neurological Disease
|
|
Lurosetron (GR-87442) is a 6-fluoro analogue of Alosetron (HY-70050A). Lurosetron is a serotonin 5-HT3 receptor antagonist. Lurosetron inhibits recombinant (rbt) CYP1A2, with an IC50 of 0.1 μM. Lurosetron also inhibits other CYP isoforms, including rbtCYP2C9 and rbtCYP3A4 with IC50s ranging between 3.5 μM and 16 μM. .
|
-
- HY-W740364
-
|
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Orthopoxvirus
|
Cancer
|
|
3'-Deoxy-3'-fluorothymidine-d3 is the deuterium labeled Alovudine (HY-B1516). Alovudine (3'-Fluoro-3'-deoxythymidine) is a mtDNA synthesis inhibitor and a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus and anti-leukemic activity .
|
-
- HY-482934
-
|
2'-fluoro-2'-deoxyinosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-Deoxy-2’-fluoroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-77932S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Dibenzyloxy Tezacaftor-d4 is the deuterium labeled (R)-N-(1-(3-(benzyloxy)-2-hydroxypropyl)-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-5-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide (HY-77932).
|
-
- HY-W008598
-
|
p-fluorophenacyl bromide
|
DNA/RNA Synthesis
|
Cancer
|
|
2-Bromo-4'-fluoroacetophenone is a photoinduced DNA cleaving agent that serves as a precursor for fluoro-substituted phenyl radicals, generating highly reactive radicals upon illumination to mediate DNA strand breakage.
|
-
- HY-B0021
-
|
Ro 21-9738; 5-fluoro-5'-deoxyuridine; 5'-DFUR
|
Thymidylate Synthase
|
Cancer
|
|
Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .
|
-
- HY-100496
-
|
4'-fluoro-5'-O-sulfamoyladenosine; NSC 521007
|
Bacterial
|
Infection
|
|
Nucleocidin is an antitrypanosomal antibiotic, inhibiting the transfer of labeled amino acid from S-RNA to protein.
|
-
- HY-150760
-
|
GSK2485852
|
HCV
|
Inflammation/Immunology
|
|
GSK5852 (GSK2485852) is an HCV NS5B polymerase inhibitor, with an IC50 value of 50 nM. GSK5852 displays antiviral activity and inhibits HCV with EC50s of 3.0 nM (genotype 1a, GT1a) and 1.7 nM (GT1b), respectively .
|
-
- HY-W016819B
-
|
5-fluorouracil-6-carboxylic acid Mono(hydrate); 5-FOA; 5-fluoro OA
|
Thymidylate Synthase
Parasite
|
Infection
|
|
5-Fluoroorotic acid monohydrate is the monohydrate salt form of 5-Fluoroorotic acid (HY-W016819).
5-Fluoroorotic acid monohydrate is the inhibitor for thymidylate synthase that acts as a selective agent in yeast molecular genetics. 5-Fluoroorotic acid monohydrate exhibits antimalarial activity .
|
-
- HY-W010023
-
|
3-Bromo-5-fluoro-2-pyridinamine
|
Biochemical Assay Reagents
|
Others
|
|
2-Amino-3-bromo-5-fluoropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W115309
-
|
5'-DMT-2'-F-ibu-dG
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets .
|
-
- HY-W800683
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Azide-TFP-Amide-SS-Sulfo-NHS consists of an aryl azide, a cleavable disulfide bond, and an NHS ester. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The NHS ester reacts with amines. The disulfide bond can be cleaved by reducing agents.
|
-
- HY-100449A
-
|
|
Prostaglandin Receptor
|
Endocrinology
|
|
(S)-AL 8810 is an 11β-fluoro analog of PGF2α that acts as a potent and selective antagonist at the FP receptor. (S)-AL 8810 is the C-15 epimer of AL 8810, having the
inverse, (S), or "natural" configuration at C-15 relative to AL 8810, which is 15-(R) .
|
-
- HY-B0021R
-
|
Ro 21-9738 (Standard); 5-fluoro-5'-deoxyuridine (Standard); 5'-DFUR (Standard)
|
Thymidylate Synthase
Reference Standards
|
Cancer
|
|
Doxifluridine (Standard) is the analytical standard of Doxifluridine. This product is intended for research and analytical applications. Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .
|
-
- HY-U00323
-
-
- HY-W800632
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Azide-TFP-Amide-SS-propionic acid contains an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The carboxylic acid can be reacted with amines in the presence of an activator to form an amide bond. The disulfide bond can be cleaved via reducing agents.
|
-
- HY-124200
-
|
|
Prostaglandin Receptor
|
Endocrinology
|
|
AL 8810 (Item No. 16735) is an 11β-fluoro analog of prostaglandin F2α which acts as a potent and selective antagonist at the FP receptor. AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost (HY-B0577) and Travoprost (HY-B0584).
|
-
- HY-136649
-
|
AfTP tetralithium, 2′-fluoro-2′-deoxy-ATP tetralithium）
|
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium is an ATP analog, it exerted a strong but mixed-type inhibition on poly(AU) synthesis.
|
-
- HY-W800635
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Azide-TFP-Amide-PEG4-acid contains an aryl azide and a carboxylic acid with a PEG spacer to increase aqueous solubility and decrease steric hinderance during ligation. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The carboxylic acid can be reacted with amines in the presence of an activator to form an amide bond.
|
-
- HY-W014431S
-
|
3-fluoro-5-bromochlorobenzene-d3
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-3-chloro-5-fluorobenzene-d3 is the deuterium labeled 1-Bromo-3-chloro-5-fluorobenzene .
|
-
- HY-45491
-
|
2'-F-Ac-dC Phosphoramidite; DMT-2′fluoro-dC(ac) Phosphoramidite
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .
|
-
- HY-12504
-
Pyr6
1 Publications Verification
N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide
|
CRAC Channel
|
Others
|
|
Pyr6 is a selective store operated calcium entry (SOCE) inhibitor with an IC50 of 0.49 μM. Pyr6 displays 37-fold higher potency for RBL SOCE than for TRPC3 ROCE .
|
-
- HY-W039442
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP .
|
-
- HY-400770
-
|
1-(2-Amino-4-fluoro-5-methylphenyl)-2-chloroethanone
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
MC-GGFG-AM-(10Me-11F-Camptothecin) intermediate-1 (compound 19-2) is an intermediate for the synthesis of MC-GGFG-AM-(10Me-11F-Camptothecin) (HY-153360). Modifying groups can be added group. MC-GGFG-AM-(10Me-11F-Camptothecin) is a drug-linker conjugate used in the synthesis of ADCs .
|
-
- HY-Y0225S
-
-
- HY-W034041
-
|
Tris(2-(4-fluorophenyl)pyridine)iridium; Tris[5-fluoro-2-(2-pyridinyl-kN)phenyl-kC]iridium(III)
|
Endogenous Metabolite
|
|
|
Ir(pF-ppy)3 (Tris(2-(4-fluorophenyl)pyridine)iridium) is a compound that catalyzes photoreactions and has excellent photocatalytic activity. Ir(pF-ppy)3 can be used as a catalyst in organic reactions, especially in photocatalytic synthesis. Ir(pF-ppy)3 shows its unique advantages in promoting electron transfer and improving reaction selectivity. Ir(pF-ppy)3 is also used to improve the efficiency of displays and solar cells.
|
-
- HY-B0021S
-
|
Ro 21-9738-d2; 5-fluoro-5'-deoxyuridine-d2; 5'-DFUR-d2
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Doxifluridine-d2 is the deuterium labeled Doxifluridine . Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.
|
-
- HY-B0021S1
-
|
Ro 21-9738-d3; 5-fluoro-5'-deoxyuridine-d3; 5'-DFUR-d3
|
Thymidylate Synthase
Isotope-Labeled Compounds
|
Cancer
|
|
Doxifluridine-d3 is deuterated labeled Doxifluridine (HY-B0021). Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .
|
-
- HY-I0096
-
|
|
iGluR
HIV
HIV Integrase
|
Neurological Disease
|
|
Indole-2-carboxylic acid (I2CA) is a competitive antagonist of the glycine site of the NMDA receptor (Ki=15 μM, 5-fluoro-I2CA) and an inhibitor of HIV-1 integrase. Indole-2-carboxylic acid is selective for the glycine site of the NMDA receptor and blocks the enhancement of NMDA receptor by competitively inhibiting the binding of glycine to the NMDA receptor. Indole-2-carboxylic acid can also inhibit the strand transfer activity of HIV-1 integrase by chelating Mg 2+ at the active site of integrase and interacting with the hydrophobic cavity. Indole-2-carboxylic acid can be used in the study of neurological diseases (such as stroke, epilepsy) and HIV-1 infection .
|
-
- HY-42118S
-
|
N-[(4-fluorophenyl)methyl]-1-methyl-4-piperidinamine-d2; (4-fluoro-benzyl)-(1-methyl-piperidin-4-yl)-amine-d2
|
Isotope-Labeled Compounds
|
Others
|
|
4-(4-Fluorobenzylamino)-1-methylpiperidine-d2 (N-[(4-Fluorophenyl)methyl]-1-methyl-4-piperidinamine-d2) is the deuterium labeled 4-(4-Fluorobenzylamino)-1-methylpiperidine.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0102
-
|
ABD-F
|
Fluorescent Dyes/Probes
|
|
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent for the sensitive and specific detection of thiols. 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole has low fluorescence background, and good stability of fluorophor .
|
-
- HY-D0785
-
|
4-fluoro-7-nitrobenzofurazan
|
Fluorescent Dyes/Probes
|
|
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent which is developed for amino acid analysis. NBD-F reacts with primary or secondary amines to produce a fluorescent product and used for analysis of amino acids and low molecular weight amines .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W008186
-
|
fluorohydroxybenzoicacid
|
Biochemical Assay Reagents
|
|
4-Fluoro-2-hydroxybenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002291
-
|
4-fluoro-L-phenylalanine
|
Biochemical Assay Reagents
|
|
p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine specific receptor of Escherichia coli (KD=0.26 μM) .
|
-
- HY-59289
-
|
2-fluoro-6-methoxyphenylboronic acid
|
Biochemical Assay Reagents
|
|
2-Fluoro-6-methoxybenzeneboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007614
-
|
3-fluoro-para-anisaldehyde
|
Biochemical Assay Reagents
|
|
3-Fluoro-4-methoxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W005085
-
|
5-fluoro-O-Anisaldehyde
|
Biochemical Assay Reagents
|
|
5-Fluoro-2-methoxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-32914
-
|
|
Biochemical Assay Reagents
|
|
4-Fluoro-2-methylphenylboronic acid is an arylboronic acid. 4-Fluoro-2-methylphenylboronic acid can be used in synthesis of piperidone when reacting with 3,4-dihydropyridine-1(2H)-carboxylate .
|
-
- HY-I0561
-
|
5-Bromo-2-fluoro-benzaldehyde
|
Biochemical Assay Reagents
|
|
2-Fluoro-5-bromobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002914
-
|
|
Biochemical Assay Reagents
|
|
5-Fluoro-2-oxoindoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007531
-
|
|
Biochemical Assay Reagents
|
|
2-Fluoro-5-iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008088
-
|
|
Biochemical Assay Reagents
|
|
4-Fluoro-3-nitrobenzonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-32923
-
|
|
Biochemical Assay Reagents
|
|
2-Fluoro-3-methoxyphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007428
-
|
|
Biochemical Assay Reagents
|
|
3-Fluoro-2-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-34656
-
|
|
Biochemical Assay Reagents
|
|
5-Fluoro-2-pyridinecarbonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008187
-
|
|
Biochemical Assay Reagents
|
|
4-Fluoro-3-nitrobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-32924
-
|
|
Biochemical Assay Reagents
|
|
5-Fluoro-2-methoxyphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008027
-
|
|
Biochemical Assay Reagents
|
|
3-Fluoro-4-formylphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012392
-
|
|
Biochemical Assay Reagents
|
|
3-Fluoro-4-iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W007613
-
|
|
Biochemical Assay Reagents
|
|
7-Fluoro-1H-indole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-32922
-
|
|
Biochemical Assay Reagents
|
|
(3-Fluoro-4-methoxyphenyl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W000994
-
|
|
Biochemical Assay Reagents
|
|
(3-Fluoro-2-formylphenyl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-34673
-
|
o-Iodofluorobenzene
|
Biochemical Assay Reagents
|
|
1-Fluoro-2-iodobenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W288676
-
|
|
Cell Assay Reagents
|
|
6-Fluoro-3-indolyl-β-D-galactopyranoside is a chromogenic enzyme substrate commonly used in microbiology to detect the expression of β-galactosidase in bacterial colonies.
|
-
- HY-W002924
-
|
|
Biochemical Assay Reagents
|
|
6-Chloro-2-fluoro-9H-purine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-42121
-
|
4-Bromo-2-fluoroiodobenzene
|
Biochemical Assay Reagents
|
|
4-Bromo-2-fluoro-1-iodobenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-141637
-
|
2-fluoro-2-deoxy-D-glucose; 2-Deoxy-2-fluoro-D-glucopyranose
|
Carbohydrates
|
|
2-Deoxy-2-fluoro-D-glucose, a radiolabeled glucose analog, is commonly used in medical imaging techniques such as positron emission tomography (PET) scans. FDG has unique chemical properties that allow it to be taken up by cells that actively metabolize glucose, such as cancer cells or inflamed tissue. Once absorbed, FDG emits positrons that can be detected in 2-Deoxy-2-fluoro-D-glucose scans, producing images that highlight areas of high metabolic activity in the body. This makes it a useful tool for diagnosing and monitoring a variety of diseases, including cancer and neurological disorders.
|
-
- HY-21997
-
|
|
Gene Sequencing and Synthesis
|
|
DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity .
|
-
- HY-W854371
-
|
|
Carbohydrates
|
|
D-Arabinofuranose,2-deoxy-2-fluoro,1,3,5-triacetateis a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W355280
-
|
|
Carbohydrates
|
|
α-D-Glucopyranoside,methyl 4-deoxy-4-fluoro,2,3,6-tribenzoate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W415930
-
|
|
Carbohydrates
|
|
3-Deoxy-3-fluoro-D-galactose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W415934
-
|
|
Carbohydrates
|
|
4-Deoxy-4-fluoro-D-mannose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W357096
-
|
|
Carbohydrates
|
|
4-Deoxy-4-fluoro-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W415931
-
|
|
Carbohydrates
|
|
3-Deoxy-3-fluoro-D-mannose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W743751
-
|
|
Carbohydrates
|
|
2-Deoxy-2-fluoro-D-galactose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W699426
-
|
|
Carbohydrates
|
|
D-Galactopyranose,4-deoxy-4-fluoro,tetraacetate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W739643
-
|
|
Carbohydrates
|
|
Methyl 4-deoxy-4-fluoro-α-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W699259
-
|
|
Carbohydrates
|
|
Phenylmethyl 2-(acetylamino)-2,4-dideoxy-4-fluoro-α-D-glucopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W699260
-
|
|
Carbohydrates
|
|
Benzyl 2-acetamido-3,6-di-O-benzoyl-2,4-dideoxy-4-fluoro-α-D-glucopyranose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-Glycan recognition and the role of glycans in biological systems. This field is closely related to basic research, biomedicine and biotechnology.
|
-
- HY-Y0680
-
|
|
Biochemical Assay Reagents
|
|
4-Fluoro-3-chloroaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W001028
-
|
|
Biochemical Assay Reagents
|
|
3-Fluoro-2-formylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007331
-
|
|
Biochemical Assay Reagents
|
|
5-Fluoro-2-hydroxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W114781
-
|
|
Biochemical Assay Reagents
|
|
1-(4-Fluorophenyl)-N-methylmethanamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010023
-
|
3-Bromo-5-fluoro-2-pyridinamine
|
Biochemical Assay Reagents
|
|
2-Amino-3-bromo-5-fluoropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W021482
-
-
- HY-W009794
-
-
- HY-79295
-
|
N-BOC-3-fluoro-D-phenylalanine; N-tert-Butoxycarbonyl-3-fluoro-D-phenylalanine
|
Amino Acid Derivatives
|
Others
|
|
N-BOC-3-Fluoro-D-phenylalanine is a phenylalanine derivative .
|
-
- HY-77026
-
-
- HY-I0124
-
-
- HY-P5373
-
|
|
Peptides
|
Others
|
|
Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed
the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the
Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)
|
-
- HY-P5372
-
|
|
Protease Activated Receptor (PAR)
|
Others
|
|
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biological active peptide. (Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This peptide is a PAR-1 selective agonist displaying a high level of specificity to PAR-1 over PAR-2. The specificity of peptide was evaluated in cell-based calcium signaling assay using HEK293 cells. PAR-1 selective agonists can be used to study PAR-1 activation in vivo. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.)
|
-
- HY-W016336
-
-
- HY-W141942
-
-
- HY-77021
-
-
- HY-77151
-
-
- HY-I0125
-
-
- HY-W046071
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-trans-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003222
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-tert-Boc-cis-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W061614
-
|
|
Amino Acid Derivatives
|
Others
|
|
(4R)-1-Boc-4-fluoro-D-proline is an amino acid derivative that can be used for preparation of peptidomimetics, dihydropyridopyrimidines and pyridopyrimidines .
|
-
- HY-P2496
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-I0096
-
|
|
Structural Classification
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
|
iGluR
HIV
HIV Integrase
|
|
Indole-2-carboxylic acid (I2CA) is a competitive antagonist of the glycine site of the NMDA receptor (Ki=15 μM, 5-fluoro-I2CA) and an inhibitor of HIV-1 integrase. Indole-2-carboxylic acid is selective for the glycine site of the NMDA receptor and blocks the enhancement of NMDA receptor by competitively inhibiting the binding of glycine to the NMDA receptor. Indole-2-carboxylic acid can also inhibit the strand transfer activity of HIV-1 integrase by chelating Mg 2+ at the active site of integrase and interacting with the hydrophobic cavity. Indole-2-carboxylic acid can be used in the study of neurological diseases (such as stroke, epilepsy) and HIV-1 infection .
|
-
-
- HY-125150
-
-
-
- HY-100496
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-142907S
-
|
|
|
(2-Fluoro-4-biphenyl)acetic acid-d5 is the deuterium labeled (2-Fluoro-4-biphenyl)acetic acid .
|
-
-
- HY-W001260S
-
|
|
|
3-Fluoro-4-(hydroxymethyl)benzonitrile-d2 is the deuterium labeled 3-Fluoro-4-(hydroxymethyl)benzonitrile (HY-W001260).
|
-
-
- HY-W744592
-
|
|
|
4-Desacetamido-4-fluoro Andarine-d4 is deuterium-labeled 4-Desacetamido-4-fluoro Andarine .
|
-
-
- HY-W704668
-
|
|
|
4-Fluoro-2-(methoxy-d3)-1-nitrobenzene is the deuterium labeled 5-Fluoro-2-nitroanisole (HY-Y0205).
|
-
-
- HY-W751668
-
|
|
|
B-[2-Fluoro-3-(methoxy-d3)phenyl]boronic Acid is the deuterium labeled B-[2-Fluoro-3-(methoxy)phenyl]boronic Acid.
|
-
-
- HY-W012808S
-
|
|
|
2-Fluoro-1,3-bis(methyl)benzene-d6 is the deuterium labeled 2-Fluoro-1,3-dimethylbenzene (HY-W012808) .
|
-
-
- HY-W015849S
-
|
|
|
1-Fluoro-4-methoxybenzene-d4 is the deuterium labeled 1-Fluoro-4-methoxybenzene .
|
-
-
- HY-157386S
-
|
|
|
8-(o-Fluoro-benzyl)theophylline methylsulfonyl- 13C2 is a 13C labeled 8-(o-Fluoro-benzyl)theophylline methylsulfonyl.
|
-
-
- HY-141637S
-
|
|
|
2-Deoxy-2-fluoro-D-glucose- 13C is the 13C labeled 2-Deoxy-2-fluoro-D-glucose .
|
-
-
- HY-146990S
-
|
|
|
3-Deoxy-3-fluoro-D-glucose- 13C is the 13C labeled 3-Deoxy-3-fluoro-D-glucose .
|
-
-
- HY-78467S
-
|
|
|
4-Bromo-2-fluoro-N-methylbenzamide-d3 is the deuterium labeled 4-Bromo-2-fluoro-N-methylbenzamide (HY-78467).
|
-
-
- HY-W768211
-
|
|
|
2-Deoxy-2-fluoro-D-glucose- 13C6 is the 13C-labeled 2-Deoxy-2-fluoro-D-glucose.
|
-
-
- HY-141637S1
-
|
|
|
2-Deoxy-2-fluoro-D-glucose- 13C,d7 is the 13C-labeled and deuterium labeled 2-Deoxy-2-fluoro-D-glucose (HY-141637) . 2-Deoxy-2-fluoro-D-glucose, a radiolabeled glucose analog, is commonly used in medical imaging techniques such as positron emission tomography (PET) scans. FDG has unique chemical properties that allow it to be taken up by cells that actively metabolize glucose, such as cancer cells or inflamed tissue. Once absorbed, FDG emits positrons that can be detected in 2-Deoxy-2-fluoro-D-glucose scans, producing images that highlight areas of high metabolic activity in the body. This makes it a useful tool for diagnosing and monitoring a variety of diseases, including cancer and neurological disorders.
|
-
-
- HY-W416378S
-
|
|
|
4-Fluoro-N,N-diisopropylbenzamide-d4 (N,N-Diisopropyl-4-fluorobenzamide-d4) is the deuterium labeled 4-Fluoro-N,N-diisopropylbenzamide (HY-W416378) .
|
-
-
- HY-W285163S
-
|
|
|
1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-d8 is deuterated labeled 1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid.
|
-
-
- HY-W009538S
-
|
|
|
5'-Deoxy-5-fluorocytidine-d3 is deuterated labeled 5'-Deoxy-5-fluorocytidine (HY-W009538). 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
|
-
-
- HY-W009538S1
-
|
|
|
5'-Deoxy-5-fluorocytidine-13C5 is the 13C labeled isotope of 5'-Deoxy-5-fluorocytidine (HY-W009538). 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
|
-
-
- HY-W013775S
-
|
|
|
9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid-d8 hydrochloride is the deuterium labeled 9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride .
|
-
-
- HY-W740364
-
|
|
|
3'-Deoxy-3'-fluorothymidine-d3 is the deuterium labeled Alovudine (HY-B1516). Alovudine (3'-Fluoro-3'-deoxythymidine) is a mtDNA synthesis inhibitor and a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus and anti-leukemic activity .
|
-
-
- HY-77932S
-
|
|
|
Dibenzyloxy Tezacaftor-d4 is the deuterium labeled (R)-N-(1-(3-(benzyloxy)-2-hydroxypropyl)-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-5-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide (HY-77932).
|
-
-
- HY-W014431S
-
|
|
|
1-Bromo-3-chloro-5-fluorobenzene-d3 is the deuterium labeled 1-Bromo-3-chloro-5-fluorobenzene .
|
-
-
- HY-Y0225S
-
|
|
|
p-Fluorophenol-d6 is the deuterium labeled p-Fluorophenol .
|
-
-
- HY-B0021S
-
|
|
|
Doxifluridine-d2 is the deuterium labeled Doxifluridine . Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.
|
-
-
- HY-B0021S1
-
|
|
|
Doxifluridine-d3 is deuterated labeled Doxifluridine (HY-B0021). Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .
|
-
-
- HY-42118S
-
|
|
|
4-(4-Fluorobenzylamino)-1-methylpiperidine-d2 (N-[(4-Fluorophenyl)methyl]-1-methyl-4-piperidinamine-d2) is the deuterium labeled 4-(4-Fluorobenzylamino)-1-methylpiperidine.
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-152364
-
|
|
|
Alkynes
|
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-152782
-
|
|
|
Azide
|
|
4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-152585
-
|
|
|
Azide
|
|
3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-152597
-
|
|
|
Azide
|
|
3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-152310
-
|
|
|
Azide
|
|
N4-(n-Palmitoyl)-4’-azido-2’-deoxy-2’-fluoro-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities . N4-(n-Palmitoyl)-4’-azido-2’-deoxy-2’-fluoro-arabinocytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-152373
-
|
|
|
Alkynes
|
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154678
-
|
|
|
Azide
|
|
4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W616732
-
-
- HY-160428
-
|
|
|
Nucleoside Phosphoramidites
C
|
|
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite (compound 1B) is a phosphoramidite of 5-Fluoro-2'-deoxycytidine .
|
-
- HY-152298
-
|
|
|
Nucleosides and their Analogs
U
|
|
5-Fluoro-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152522
-
|
|
|
Nucleosides and their Analogs
U
|
|
5-Fluoro-4’-C-methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-152526
-
|
|
|
Nucleosides and their Analogs
C
|
|
5-Fluoro-4’-C-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-152640
-
|
|
|
Nucleosides and their Analogs
C
|
|
5-Fluoro-4’-thio-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-148167
-
|
|
|
Nucleosides and their Analogs
U
|
|
2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication .
|
-
- HY-152763
-
|
|
|
Nucleosides and their Analogs
C
|
|
2’-Deoxy-2’-fluoro-5-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154136
-
|
|
|
Nucleosides and their Analogs
U
|
|
5-Fluoro-3’-beta-C-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152612
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-5-hydroxymethyl arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-152820
-
|
|
|
Nucleosides and their Analogs
U
|
|
2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-152757
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152754
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152753
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152760
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W539754
-
|
|
|
Nucleosides and their Analogs
U
|
|
2'-Deoxy-2'-fluoro-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152302
-
|
|
|
Nucleosides and their Analogs
C
|
|
3’-Deoxy-3’-fluoro-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152761
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-5-methoxyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152329
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152674
-
|
|
|
Nucleosides and their Analogs
U
|
|
2′-Deoxy-2′-fluoro-5-methoxy-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-152811
-
|
|
|
Nucleosides and their Analogs
C
|
|
2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-W342664
-
|
FIRU
|
|
Nucleosides and their Analogs
U
|
|
2'-Deoxy-2'-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152813
-
|
|
|
Nucleosides and their Analogs
U
|
|
2′-Deoxy-2′-fluoro-4-deoxy-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152489
-
|
|
|
Nucleosides and their Analogs
I
|
|
8-Chloro-2’-deoxy-2’-fluoro inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154531
-
|
|
|
Nucleosides and their Analogs
C
|
|
2′,3′-Dideoxy-3′-fluoro-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154203
-
|
|
|
Nucleosides and their Analogs
U
|
|
4-Deoxy-3’-deoxy-3’-fluoro uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152815
-
|
|
|
Nucleosides and their Analogs
U
|
|
2′-Deoxy-2′-fluoro-3-deaza-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152390
-
|
|
|
Nucleosides and their Analogs
A
|
|
2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-45409
-
|
2'-F-dU Phosphoramidite
|
|
Nucleoside Phosphoramidites
U
|
|
DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA .
|
-
- HY-48973
-
|
|
|
Nucleosides and their Analogs
U
|
|
2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-W089288
-
|
N6-Benzoyl-2'-fluoro-2'-deoxyadenosine
|
|
Nucleosides and their Analogs
A
|
|
2'-F-Bz-A (N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
|
-
- HY-154246
-
|
|
|
Nucleosides and their Analogs
A
|
|
2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152736
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154037
-
|
|
|
Nucleosides and their Analogs
A
|
|
N6-Benzoyl-3'-fluoro-2',3'-dideoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154605
-
|
|
|
Nucleosides and their Analogs
G
|
|
N2-iso-Butyroyl-2’-fluoro-2’-deoxyarabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154414
-
|
|
|
Nucleosides and their Analogs
C
|
|
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-W334680
-
|
|
|
Nucleosides and their Analogs
|
|
2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154612
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-4’-thio-a-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152350
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-4’-thio-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152527
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152392
-
|
|
|
Nucleosides and their Analogs
A
|
|
2’-Fluoro-2’-deoxy-N6,N6-dimethylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154463
-
|
|
|
Nucleosides and their Analogs
G
|
|
N2-iso-Butyroyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154321
-
-
- HY-W072701
-
|
|
|
Nucleosides and their Analogs
A
|
|
N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-154608
-
|
|
|
Nucleoside Phosphoramidites
U
|
|
3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluoro uridine-2’-CED-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-154352
-
-
- HY-154236
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-21997
-
|
|
|
Nucleoside Phosphoramidites
A
|
|
DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity .
|
-
- HY-152364
-
|
|
|
Nucleosides and their Analogs
G
|
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-134554
-
- HY-152759
-
|
|
|
Nucleosides and their Analogs
C
|
|
3’-Deoxy-3’-fluoro-xylocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152584
-
|
|
|
Nucleosides and their Analogs
G
|
|
3’-Deoxy-3’-fluoro-xyloguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152554
-
|
|
|
Nucleosides and their Analogs
A
|
|
3’-Deoxy-3’-fluoro-xyloadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-W555583
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152532
-
|
|
|
Nucleosides and their Analogs
G
|
|
2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152605
-
|
|
|
Nucleosides and their Analogs
I
|
|
2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-arabino-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154409
-
|
|
|
Nucleoside Phosphoramidites
A
|
|
2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-154611
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152348
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154315
-
|
|
|
Nucleosides and their Analogs
U
|
|
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154316
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-3-Deaza-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154312
-
|
|
|
Nucleosides and their Analogs
U
|
|
3,5-Di-O-benzoyl-2-deoxy-2-fluoro-5-trifluoromethyl-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-148019
-
|
|
|
Nucleosides and their Analogs
A
|
|
2′-Deoxy-2′-fluoro-N-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154296
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-ara-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154459
-
|
|
|
Nucleosides and their Analogs
C
|
|
N4-Benzoyl-2’-deoxy-5’-O-DMTr-2’-fluoro- 5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-W113972
-
|
2′-Deoxy-2′-fluoro-N-isobutyrylguanosine
|
|
Nucleosides and their Analogs
G
|
|
2'-F-iBu-G (2′-Deoxy-2′-fluoro-N-isobutyrylguanosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
|
- HY-W128788A
-
|
|
|
Nucleosides and their Analogs
C
|
|
2’-Deoxy-2’-fluoro-b-D-arabinocytidine(hydrochloride) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154078
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154726
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro- N3-(2S)-(2-amino-3-carbonyl)-propyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154071
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154083
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154072
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154447
-
|
|
|
Nucleosides and their Analogs
I
|
|
5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154231
-
|
|
|
Nucleosides and their Analogs
G
|
|
2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-W141392
-
|
|
|
Nucleoside Phosphoramidites
I
|
|
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
- HY-152504
-
|
|
|
Nucleosides and their Analogs
A
|
|
2’-Deoxy-2’-fluoro-N1-methyladensoine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154291
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-N1-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154133
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-xylo-5-methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152340
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Amino-2’-deoxy-5-fluoro-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154295
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N1-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152301
-
|
|
|
Nucleosides and their Analogs
A
|
|
3’-Deoxy-3’-fluoro-N6-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152403
-
|
|
|
Nucleosides and their Analogs
C
|
|
3’-Deoxy-3’-fluoro-xylo-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154134
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Deoxy-3’-fluoro-xylo-5-trifluoromethyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154185
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-methyl-β-D-arabino-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152457
-
|
|
|
Nucleosides and their Analogs
I
|
|
3’-Deoxy-3’-fluoro-beta-D-xylo-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152782
-
|
|
|
Nucleosides and their Analogs
U
|
|
4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W009538
-
|
5-fluoro-5'-deoxycytidine
|
|
Nucleosides and their Analogs
C
|
|
5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
|
- HY-152634
-
|
|
|
Nucleosides and their Analogs
A
|
|
8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152492
-
|
|
|
Nucleosides and their Analogs
I
|
|
2’-Deoxy-2’-fluoro-N1-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-W128788
-
|
4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
|
|
Nucleosides and their Analogs
C
|
|
2’-Deoxy-2’-fluoro-b-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152585
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-152597
-
|
|
|
Nucleosides and their Analogs
C
|
|
3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-154362
-
|
|
|
Nucleosides and their Analogs
|
|
1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-45492
-
|
2'-F-ibu-dG Phosphoramidite
|
|
Nucleoside Phosphoramidites
G
|
|
DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine .
|
- HY-152705
-
|
|
|
Nucleosides and their Analogs
C
|
|
5-Bromo-2’-deoxy-2’-fluoro-beta-D-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-112120
-
|
|
|
Nucleosides and their Analogs
|
|
2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine ((2R,3S,4S,5R)-2-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152880
-
|
T 70179
|
|
Nucleosides and their Analogs
|
|
2’-Deoxy-2’-fluoro-arabino-tubercidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154779
-
|
|
|
Nucleosides and their Analogs
C
|
|
5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152769
-
|
|
|
Nucleosides and their Analogs
A
|
|
2-Methoxy-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152378
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152864
-
|
|
|
Nucleosides and their Analogs
|
|
6-Methylpurine-2’-deoxy-2’-fluoro-beta-D-arabinoriboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152349
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-β-D-arabino-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154680
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154727
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-(3-aminopropyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154682
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154489
-
|
|
|
Nucleosides and their Analogs
U
|
|
5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154723
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-(4-hydroxybenzyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154410
-
|
|
|
Nucleosides and their Analogs
U
|
|
5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
- HY-152374
-
|
|
|
Nucleosides and their Analogs
A
|
|
3’-Deoxy-3’-fluoro-N6,N6-dimethyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-49198
-
|
|
|
Nucleosides and their Analogs
C
|
|
2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152987
-
|
|
|
Nucleosides and their Analogs
|
|
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .
|
- HY-152661
-
|
|
|
Nucleosides and their Analogs
A
|
|
2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152404
-
|
|
|
Nucleosides and their Analogs
A
|
|
3’-Deoxy-3’-fluoro-xylo-N6-(m-methoxybenzyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154412
-
|
|
|
Nucleosides and their Analogs
C
|
|
N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152762
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154135
-
|
|
|
Nucleosides and their Analogs
A
|
|
3’-Deoxy-3’-fluoro-xylo-N6-(p-methoxybenzyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152691
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
- HY-152310
-
|
|
|
Nucleosides and their Analogs
C
|
|
N4-(n-Palmitoyl)-4’-azido-2’-deoxy-2’-fluoro-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities . N4-(n-Palmitoyl)-4’-azido-2’-deoxy-2’-fluoro-arabinocytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-152792
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]uridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
- HY-152785
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154725
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152689
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152780
-
|
|
|
Nucleosides and their Analogs
|
|
9-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152373
-
|
|
|
Nucleosides and their Analogs
G
|
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-154681
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-[(pyrid-4-yl)methyl]uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152695
-
|
|
|
Nucleosides and their Analogs
|
|
6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154683
-
|
|
|
Nucleosides and their Analogs
C
|
|
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154583
-
|
|
|
Nucleosides and their Analogs
U
|
|
3’,5’-Bis-O-benzoyl-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154555
-
|
|
|
Nucleosides and their Analogs
U
|
|
5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152766
-
|
|
|
Nucleosides and their Analogs
|
|
6-(Thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152460
-
|
|
|
Nucleosides and their Analogs
A
|
|
2-Chloro-N6-cyclopentyl-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152772
-
|
|
|
Nucleosides and their Analogs
|
|
2-Amino-6-chloropurine-9-beta-D-(2’-deoxy-2’-fluoro)-arabinoriboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152690
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152734
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152809
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152727
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154658
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-[(pyrid-4-yl)methyl]-beta-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154643
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152776
-
|
|
|
Nucleosides and their Analogs
|
|
2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152791
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-methyl-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-147080
-
|
ARC1905
|
|
Aptamers
|
|
Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system. Avacincaptad pegol sodium treats Geographic atrophy (GA) mice .
|
- HY-148457
-
|
|
|
Aptamers
|
|
Avacincaptad pegol, which is a pegylated aptamer, has garnered significant attention as a C5 complement inhibitor that may reduce inflammation-related retinal pigment epithelium (RPE) damage. Avacincaptad pegol caqn be used for the research of stargardt macular dystrophy (STGD1) and geographic atrophy (GA) .
|
- HY-132587
-
|
ALN-AT3SC; SAR439774
|
|
siRNAs
siRNA drugs
|
|
Fitusiran (ALN-AT3SC), an small interfering RNA, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. Fitusiran increases thrombin generation and has the potential for the research of the hemophilia .
|
- HY-154604
-
|
|
|
Nucleoside Phosphoramidites
T
|
|
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
- HY-147278
-
|
Divesiran
|
|
siRNAs
siRNA drugs
|
|
Manusiran (SLN124), a GalNAc conjugated 19-mer siRNA targeting TMPRSS6 (transmembrane protease serine 6), reduces plasma iron and increases hepcidin levels of healthy volunteers [1][2].
|
- HY-145720
-
|
ALN-CC5
|
|
siRNAs
siRNA drugs
|
|
Cemdisiran is an N-acetylgalactosamine (GalNAc) conjugated siRNA for the research of complement-mediated diseases by suppressing liver production of complement 5 (C5) protein.
|
- HY-109561
-
|
EYE001; NX1838
|
|
Aptamers
|
|
Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) .
|
- HY-132592
-
|
WVE-210201
|
|
Antisense Oligonucleotides
|
|
Suvodirsen (WVE-210201) is a oligonucleotide. Suvodirsen has the potential for study Duchenne muscular dystrophy (DMD) .
|
- HY-132610
-
|
ALN-AS1
|
|
siRNAs
siRNA drugs
|
|
Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid and porphobilinogen levels. Givosiran can be used for the research of acute intermittent porphyria .
|
- HY-154618
-
|
|
|
Nucleoside Phosphoramidites
C
|
|
N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-3’-deoxy-3’-fluoro-beta-D-xylofuranosyl cytidine-2’-CED-phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-132602
-
|
MRG-201
|
|
MicroRNAs
|
|
Remlarsen (MRG-201), a miR-29b mimic, acts a miR-29b agonist. Remlarsen has the potential for preventiong formation of a fibrotic scar or cutaneous fibrosis .
|
- HY-154733
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-147425
-
|
SLN360
|
|
siRNAs
siRNA drugs
|
|
Zerlasiran is an apolipoprotein A (ApoA) synthesis reducer .
|
- HY-132591
-
|
ALN-PCSsc
|
|
siRNAs
siRNA drugs
|
|
Inclisiran is a double-stranded small interfering RNA (siRNA) molecule. Inclisiran inhibits the transcription of PCSK9. Inclisiran inhibits Pyroptosis, activates PPARγ, and reduces NLRP3, cleaved caspase-1, IL-1β, and IL-18. Inclisiran has anti-inflammatory, lipid-regulating and anti-atherosclerotic activities. Inclisiran can be used in researches of hyperlipidemia and cardiovascular disease (CVD) .
|
- HY-152709
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154118
-
|
|
|
Nucleosides and their Analogs
U
|
|
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabino-6-azidouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154676
-
|
|
|
Nucleosides and their Analogs
|
|
Purine-9-b-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-132604
-
|
ARO-AAT
|
|
siRNAs
siRNA drugs
|
|
Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease.
|
- HY-132613
-
|
|
|
siRNAs
siRNA drugs
|
|
Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) .
|
- HY-132588
-
|
ALN-G01
|
|
siRNAs
siRNA drugs
|
|
Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1) .
|
- HY-154679
-
|
|
|
Nucleosides and their Analogs
|
|
2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152788
-
|
|
|
Nucleosides and their Analogs
|
|
2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154335
-
|
|
|
Nucleosides and their Analogs
|
|
1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-132589
-
|
ALN-TTRsc02
|
|
siRNAs
siRNA drugs
|
|
Vutrisiran (ALN-TTRsc02) is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran can be used for transthyretin (TTR)-mediated amyloidosis research .
|
- HY-152485
-
|
|
|
Nucleosides and their Analogs
A
|
|
2-Amino-N6,N6-dimethyl-2’-deoxy-2’-fluoro-beta-D-arabino-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154675
-
|
|
|
Nucleosides and their Analogs
|
|
2-Aminopurine-9-beta-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152686
-
|
|
|
Nucleosides and their Analogs
|
|
2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154678
-
|
|
|
Nucleosides and their Analogs
U
|
|
4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-152676
-
|
|
|
Nucleosides and their Analogs
|
|
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
- HY-152687
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl) pyridin-3-yl]purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152704
-
|
|
|
Nucleosides and their Analogs
|
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154662
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154724
-
|
|
|
Nucleosides and their Analogs
U
|
|
2’-Deoxy-2’-fluoro-N3-(2S)-[2-(tert-butoxy-carbonyl)-amino-3-carbonyl]propyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152773
-
|
|
|
Nucleosides and their Analogs
|
|
2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-W605935
-
|
|
|
Nucleosides and their Analogs
|
|
2-Amino-6-chloropurine -9-beta-D-(2’-deoxy-3’,5’-di-O-benzoyl-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-W020420
-
|
|
|
Nucleosides and their Analogs
|
|
6-Chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-W550484
-
|
|
|
Nucleosides and their Analogs
|
|
2,6-Dichloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl)-9H-purine arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-482934
-
|
2'-fluoro-2'-deoxyinosine
|
|
Nucleosides and their Analogs
I
|
|
2’-Deoxy-2’-fluoroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-W115309
-
|
5'-DMT-2'-F-ibu-dG
|
|
Nucleosides and their Analogs
G
|
|
DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets .
|
- HY-136649
-
|
AfTP tetralithium, 2′-fluoro-2′-deoxy-ATP tetralithium）
|
|
Nucleotides and their Analogs
|
|
2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium is an ATP analog, it exerted a strong but mixed-type inhibition on poly(AU) synthesis.
|
- HY-45491
-
|
2'-F-Ac-dC Phosphoramidite; DMT-2′fluoro-dC(ac) Phosphoramidite
|
|
Nucleoside Phosphoramidites
C
|
|
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .
|
- HY-W039442
-
|
|
|
Nucleosides and their Analogs
A
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2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP .
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