2. Membrane Transporter/Ion Channel
  3. EAAT
  4. 5-Fluoro-L-tryptophan

5-Fluoro-L-tryptophan  (Synonyms: L-5-Fluorotryptophan)

Cat. No.: HY-21045 Purity: 99.99%
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Handling Instructions Technical Support

5-Fluoro-L-tryptophan is a competitive vesicular glutamate transporter (VGLUT) inhibitor. 5-Fluoro-L-tryptophan is promising for research of diseases associated with the neurotransmitter systems.

For research use only. We do not sell to patients.

5-Fluoro-L-tryptophan Chemical Structure

5-Fluoro-L-tryptophan Chemical Structure

CAS No. : 16626-02-1

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Based on 1 publication(s) in Google Scholar

5-Fluoro-L-tryptophan Related Antibodies

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Description

5-Fluoro-L-tryptophan is a competitive vesicular glutamate transporter (VGLUT) inhibitor. 5-Fluoro-L-tryptophan is promising for research of diseases associated with the neurotransmitter systems[1].

Molecular Weight

222.22

Formula

C11H11FN2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@@H](N)CC1=CNC2=C1C=C(F)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 4 mg/mL (18.00 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5000 mL 22.5002 mL 45.0005 mL
5 mM 0.9000 mL 4.5000 mL 9.0001 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.99%

COA (250 KB) HNMR (124 KB) RP-HPLC (259 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.5000 mL 22.5002 mL 45.0004 mL 112.5011 mL
5 mM 0.9000 mL 4.5000 mL 9.0001 mL 22.5002 mL
10 mM 0.4500 mL 2.2500 mL 4.5000 mL 11.2501 mL
15 mM 0.3000 mL 1.5000 mL 3.0000 mL 7.5001 mL
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5-Fluoro-L-tryptophan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Fluoro-L-tryptophan16626-02-1L-5-FluorotryptophanEAATExcitatory amino acid transporter Glutamate transporter| VGLUTdiseases associated with the neurotransmitter systemsInhibitorinhibitorinhibit

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