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Results for "

first-generation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Antibiotic (24) Apoptosis (9) Autophagy (7) Bacterial (28) Calcium Channel (9) Cytochrome P450 (7) Dopamine Receptor (3) Drug Metabolite (1) Endogenous Metabolite (7) FLT3 (1) Fluorescent Dye (1) HBV (1) Histamine Receptor (20) iGluR (3) Isotope-Labeled Compounds (11) NADPH Oxidase (1) P-glycoprotein (8) Parasite (1) Phosphatase (2) Potassium Channel (5) Reference Standards (4)
By Research Areas:	Cancer (31) Cardiovascular Disease (8) Endocrinology (14) Infection (26) Inflammation/Immunology (34) Metabolic Disease (12) Neurological Disease (24)

By Targets:

Adrenergic Receptor (1)

Antibiotic (24)

Apoptosis (9)

Autophagy (7)

Bacterial (28)

Calcium Channel (9)

Cytochrome P450 (7)

Dopamine Receptor (3)

Drug Metabolite (1)

Endogenous Metabolite (7)

FLT3 (1)

Fluorescent Dye (1)

HBV (1)

Histamine Receptor (20)

iGluR (3)

Isotope-Labeled Compounds (11)

NADPH Oxidase (1)

P-glycoprotein (8)

Parasite (1)

Phosphatase (2)

Potassium Channel (5)

Reference Standards (4)

By Research Areas:

Cancer (31)

Cardiovascular Disease (8)

Endocrinology (14)

Infection (26)

Inflammation/Immunology (34)

Metabolic Disease (12)

Neurological Disease (24)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W011651

Carbutamide BZ-55	Phosphatase	Metabolic Disease
Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity .

HY-124789

TBT1	Bacterial Antibiotic	Infection
TBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC₅₀ of 13 µM .

HY-B1252

Cefalonium	Antibiotic Bacterial	Infection Inflammation/Immunology
Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-107329

Cefathiamidine	Bacterial Antibiotic	Infection
Cefathiamidine is a first-generation cephalosporin antibacterial agent and is used to treat infections caused by susceptible bacteria. Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis .

HY-B0657A

Clodronic acid disodium salt 4 Publications Verification Clodronate disodium salt	Apoptosis	Inflammation/Immunology Cancer
Clodronic acid (Clodronate) disodium salt, a first-generation bisphosphonate, is orally active osteoclastic bone resorption inhibitor. Clodronic acid disodium salt can be used in high bone turnover states, Paget ^’s disease and osteolytic bone metastases .

HY-B1252AS

Cefalonium-d4 hydrate	Isotope-Labeled Compounds	Infection
Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-W011651R

Carbutamide (Standard) BZ-55 (Standard)	Phosphatase Reference Standards	Metabolic Disease
Carbutamide (Standard) is the analytical standard of Carbutamide. This product is intended for research and analytical applications. Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity .

HY-B1252A

Cefalonium hydrate	Antibiotic Bacterial	Infection Inflammation/Immunology
Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-124789R

TBT1 (Standard)	Bacterial Antibiotic	Infection
TBT1 (Standard) is the analytical standard of TBT1. This product is intended for research and analytical applications. TBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC50 of 13 µM[1].

HY-B1252R

Cefalonium (Standard)	Antibiotic Bacterial	Infection Inflammation/Immunology
Cefalonium (Standard) is the analytical standard of Cefalonium. This product is intended for research and analytical applications. Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-100850

Piperoxan hydrochloride Benodaine hydrochloride	Adrenergic Receptor	Inflammation/Immunology Endocrinology
Piperoxan (Benodaine) hydrochloride is an α₂ adrenoceptor antagonist. Piperoxan hydrochloride is the first-generation antihistamine.

HY-107329R

Cefathiamidine (Standard)	Bacterial Antibiotic	Infection
Cefathiamidine (Standard) is the analytical standard of Cefathiamidine. This product is intended for research and analytical applications. Cefathiamidine is a first-generation cephalosporin antibacterial agent and is used to treat infections caused by susceptible bacteria. Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis[1][2].

HY-121144

Cefazedone Refosporen	Antibiotic Bacterial	Infection
Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria .

HY-D1458

Peroxyfluor 1	Fluorescent Dye	Cardiovascular Disease Neurological Disease Cancer
Peroxyfluor 1 is a cell-permeable probe for H₂O₂. Peroxyfluor 1 represents a first-generation, green-fluorescent probe .

HY-12505

CX546 4 Publications Verification	iGluR Autophagy	Neurological Disease
CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects .

HY-B0303A

Diphenhydramine hydrochloride 5 Publications Verification	Histamine Receptor Endogenous Metabolite Bacterial Apoptosis	Inflammation/Immunology Endocrinology Cancer
Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-B1296

Promethazine 1 Publications Verification (±)-Promethazine	Histamine Receptor	Neurological Disease Endocrinology
Promethazine is an orally active histamine receptor antagonist . Promethazine is first-generation antihistamine of the phenothiazine family, shows strong sedative and weak antipsychotic effects .

HY-B0881

Acetohexamide	Potassium Channel	Metabolic Disease Cancer
Acetohexamide is a first-generation sulfonylurea agent used in research related to type 2 diabetes; it stimulates the pancreas to secrete insulin.Acetohexamide inhibits ATP-sensitive potassium channels in the β cells of the pancreas .

HY-B0303

Diphenhydramine 5 Publications Verification	Histamine Receptor Bacterial Endogenous Metabolite iGluR	Neurological Disease Inflammation/Immunology Cancer
Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-B0971

Pheniramine maleate Prophenpyridamine maleate; Tripoton maleate; Pheniramine maleate	Histamine Receptor Apoptosis	Inflammation/Immunology Endocrinology
Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-B0971A

Pheniramine Prophenpyridamine; Tripoton; Pheniramine solution	Histamine Receptor Apoptosis	Inflammation/Immunology Cancer
Pheniramine (Prophenpyridamine;Tripoton) is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine displays antitumor effect and induces leukemia cells apoptosis. Pheniramine is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-B1275R

Cephalothin (sodium) (Standard)	Bacterial Antibiotic	Infection
Cephalothin (sodium) (Standard) is the analytical standard of Cephalothin (sodium). This product is intended for research and analytical applications. Cephalothin sodium is a first-generation cephalosporin antibiotic with broad antibacterial activity and is effective against Gram-positive and Gram-negative bacteria.

HY-B1078

Cefazolin sodium 5+ Cited Publications Cephazolin sodium	Bacterial Antibiotic	Infection Neurological Disease Inflammation/Immunology Cancer
Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .

HY-B1301

Triprolidine hydrochloride monohydrate	Histamine Receptor	Neurological Disease Inflammation/Immunology
Triprolidine hydrochloride monohydrate, a first-generation antihistamine, is an oral active histamine H1 antagonist. Triprolidine hydrochloride monohydrate can be used for the research of allergic rhinitis. Triprolidine hydrochloride monohydrate exhibits spinal motor and sensory block in rats .

HY-B1892

Cefazolin 5+ Cited Publications Cephazolin	Antibiotic Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .

HY-B1067R

Antazoline (hydrochloride) (Standard)	Histamine Receptor	Neurological Disease Endocrinology
Antazoline (hydrochloride) (Standard) is the analytical standard of Antazoline (hydrochloride). This product is intended for research and analytical applications. Antazoline (Phenazoline) hydrochloride is a first-generation antihistamine that also has anticholinergic properties and is used to relieve nasal congestion and is also used as eye drops.

HY-B0756

Cefazolin sodium pentahydrate Cephazolin sodium pentahydrate	Antibiotic Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
Cefazolin sodium pentahydrate is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium pentahydrate has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .

HY-B1190A

Cefadroxil hydrate 1 Publications Verification BL-S 578 hydrate	Bacterial Antibiotic	Infection
Cefadroxil hydrate (BL-S 578 hydrate) is an orally active and first-generation cephalosporin with a broad spectrum antibacterial activity. Cefadroxil hydrate (BL-S 578 hydrate) also acts as a substrate of the peptide transporter PEPT1 and PEPT2 .

HY-B0303AS1

Diphenhydramine-d5 hydrochloride	Histamine Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Diphenhydramine-d₅ (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-B0303AS

Diphenhydramine-d6 hydrochloride	Isotope-Labeled Compounds Histamine Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Diphenhydramine-d₆ (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-121144R

Cefazedone (Standard) Refosporen (Standard)	Antibiotic Bacterial	Infection
Cefazedone (Standard) (Refosporen (Standard)) is the analytical standard of Cefazedone (HY-121144). This product is intended for research and analytical applications. Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria .

HY-B0971R

Pheniramine maleate (Standard) Prophenpyridamine maleate (Standard); Tripoton maleate (Standard); Pheniramine maleate (Standard)	Reference Standards Histamine Receptor Apoptosis	Inflammation/Immunology Endocrinology
Pheniramine (maleate) (Standard) is the analytical standard of Pheniramine (maleate). This product is intended for research and analytical applications. Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-B0971AR

Pheniramine (Standard) Prophenpyridamine (Standard); Tripoton (Standard); Pheniramine solution (Standard)	Reference Standards Histamine Receptor Apoptosis	Inflammation/Immunology Cancer
Pheniramine (Standard) is the analytical standard of Pheniramine. This product is intended for research and analytical applications. Pheniramine (Prophenpyridamine;Tripoton) is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine displays antitumor effect and induces leukemia cells apoptosis. Pheniramine is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-B0303AR

Diphenhydramine (hydrochloride) (Standard) 4 Publications Verification	Histamine Receptor Endogenous Metabolite Bacterial	Inflammation/Immunology Endocrinology Cancer
Diphenhydramine (hydrochloride) (Standard) is the analytical standard of Diphenhydramine (hydrochloride). This product is intended for research and analytical applications. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-14263

Pericyazine Propericiazine; RP 8909	Dopamine Receptor	Neurological Disease
Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis . Pericyazine is a selective D2-dopamine receptor antagonist . Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects .

HY-135740

Diphenhydramine N-oxide	Drug Metabolite	Neurological Disease Inflammation/Immunology Cancer
Diphenhydramine N-oxide is a metabolite of Diphenhydramine (HY-B0303). Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine can across the ovine blood-brain barrier (BBB) .

HY-14275

Verapamil Maximum Cited Publications 61 Publications Verification (±)-Verapamil; CP-16533-1	Calcium Channel P-glycoprotein Cytochrome P450	Cardiovascular Disease Metabolic Disease Cancer
Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-A0064

Verapamil hydrochloride Maximum Cited Publications 61 Publications Verification (±)-Verapamil hydrochloride; CP-16533-1 hydrochloride	Calcium Channel P-glycoprotein Cytochrome P450	Cardiovascular Disease Cancer
Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-B0303R

Diphenhydramine (Standard)	Histamine Receptor Bacterial Endogenous Metabolite iGluR	Neurological Disease Inflammation/Immunology Cancer
Diphenhydramine (Standard) is the analytical standard of Diphenhydramine. This product is intended for research and analytical applications. Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-B1078R

Cefazolin (sodium) (Standard) Cephazolin (sodium) (Standard)	Bacterial Antibiotic	Infection Neurological Disease Inflammation/Immunology
Cefazolin (sodium) (Standard) is the analytical standard of Cefazolin (sodium). This product is intended for research and analytical applications. Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .

HY-B1892R

Cefazolin (Standard)	Antibiotic Bacterial	Infection Neurological Disease Inflammation/Immunology
Cefazolin (Standard) is the analytical standard of Cefazolin. This product is intended for research and analytical applications. Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .

HY-B1301R

Triprolidine (hydrochloride monohydrate) (Standard)	Histamine Receptor	Neurological Disease Inflammation/Immunology
Triprolidine (hydrochloride monohydrate) (Standard) is the analytical standard of Triprolidine (hydrochloride monohydrate). This product is intended for research and analytical applications. Triprolidine hydrochloride monohydrate, a first-generation antihistamine, is an oral active histamine H1 antagonist. Triprolidine hydrochloride monohydrate can be used for the research of allergic rhinitis. Triprolidine hydrochloride monohydrate exhibits spinal motor and sensory block in rats .

HY-B1190AR

Cefadroxil (hydrate) (Standard)	Bacterial Antibiotic	Infection
Cefadroxil (hydrate) (Standard) is the analytical standard of Cefadroxil (hydrate). This product is intended for research and analytical applications. Cefadroxil hydrate (BL-S 578 hydrate) is an orally active and first-generation cephalosporin with a broad spectrum antibacterial activity. Cefadroxil hydrate (BL-S 578 hydrate) also acts as a substrate of the peptide transporter PEPT1 and PEPT2 .

HY-B2072AR

Cephaloridine (hydrate) (Standard)	Antibiotic Bacterial	Infection
Cefadroxil (hydrate) (Standard) is the analytical standard of Cefadroxil (hydrate). This product is intended for research and analytical applications. Cefadroxil hydrate (BL-S 578 hydrate) is an orally active and first-generation cephalosporin with a broad spectrum antibacterial activity. Cefadroxil hydrate (BL-S 578 hydrate) also acts as a substrate of the peptide transporter PEPT1 and PEPT2 .

HY-W654098

Cefazolin-13C2,15N sodium	Isotope-Labeled Compounds Antibiotic Bacterial	Inflammation/Immunology
Cefazolin- ¹³C₂, ¹⁵N (sodium) is ¹³C and ¹⁵N labeled Cefazolin (sodium). Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).

HY-A0064S

Verapamil-d3 hydrochloride (±)-Verapamil-d₃ hydrochloride; CP-16533-1-d₃ hydrochloride	Isotope-Labeled Compounds Calcium Channel P-glycoprotein Cytochrome P450	Cardiovascular Disease
Verapamil-d₃ (hydrochloride) is the deuterium labeled Verapamil hydrochloride. Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-109195

Vebicorvir 1 Publications Verification ABI-H0731	HBV	Infection Inflammation/Immunology
Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. Vebicorvir (ABI-H0731) suppresses covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC₅₀s from 1.84 μM to 7.3 μM .

HY-B1892S1

Cefazolin-13C2,15N Cephazolin-¹³C₂,¹⁵N	Isotope-Labeled Compounds Antibiotic Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
Cefazolin- ¹³C₂, ¹⁵N (Cephazolin- ¹³C₂, ¹⁵N) is ¹³C and ¹⁵N labeled Cefazolin. Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .

HY-A0064R

Verapamil (hydrochloride) (Standard) (±)-Verapamil (hydrochloride) (Standard); CP-16533-1 (hydrochloride) (Standard)	Calcium Channel P-glycoprotein Cytochrome P450	Cardiovascular Disease Cancer
Verapamil (hydrochloride) (Standard) is the analytical standard of Verapamil (hydrochloride). This product is intended for research and analytical applications. Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-14275S

Verapamil-d3 (±)-Verapamil-d₃; CP-16533-1-d₃	Isotope-Labeled Compounds Calcium Channel Cytochrome P450 P-glycoprotein	Cardiovascular Disease Metabolic Disease Cancer
Verapamil-d₃ ((±)-Verapamil-d₃) is deuterium labeled Verapamil. Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

Cat. No.	Product Name	Type

HY-D1458

Peroxyfluor 1	Fluorescent Dyes/Probes
Peroxyfluor 1 is a cell-permeable probe for H₂O₂. Peroxyfluor 1 represents a first-generation, green-fluorescent probe .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121144

Cefazedone Refosporen	Infection Structural Classification Animals Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria .

HY-B0303A

Diphenhydramine hydrochloride 5 Publications Verification	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Histamine Receptor Endogenous Metabolite Bacterial Apoptosis
Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-B0303

Diphenhydramine 5 Publications Verification	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Histamine Receptor Bacterial Endogenous Metabolite iGluR
Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-B0303R

Diphenhydramine (Standard)	Structural Classification Alkaloids Other Alkaloids Source classification Endogenous metabolite	Histamine Receptor Bacterial Endogenous Metabolite iGluR
Diphenhydramine (Standard) is the analytical standard of Diphenhydramine. This product is intended for research and analytical applications. Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-121144R

Cefazedone (Standard) Refosporen (Standard)	Structural Classification Animals Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Antibiotic Bacterial
Cefazedone (Standard) (Refosporen (Standard)) is the analytical standard of Cefazedone (HY-121144). This product is intended for research and analytical applications. Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria .

HY-N7814R

2-Hydroxypalmitic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Endogenous Metabolite
Pheniramine (maleate) (Standard) is the analytical standard of Pheniramine (maleate). This product is intended for research and analytical applications. Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-N1514R

Ganoderenic acid B (Standard)	Triterpenes Structural Classification Human Gut Microbiota Metabolites Microorganisms Terpenoids Polyporaceae Source classification Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Endogenous metabolite	P-glycoprotein
Doxylamine (succinate) (Standard) is the analytical standard of Doxylamine (succinate). This product is intended for research and analytical applications. Doxylamine (succinate), a first generation antihistamine, is a histamine (H1) receptor antagonist. Doxylamine is also a local analgesic agent and effective hypnotic agent .

Cat. No.	Product Name	Chemical Structure

HY-B1252AS

Cefalonium-d4 hydrate
Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-B0303AS1

Diphenhydramine-d5 hydrochloride
Diphenhydramine-d₅ (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-B0303AS

Diphenhydramine-d6 hydrochloride
Diphenhydramine-d₆ (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-A0064S

Verapamil-d3 hydrochloride

Verapamil-d₃ (hydrochloride) is the deuterium labeled Verapamil hydrochloride. Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-B0781S

Promethazine-d4 hydrochloride
Promethazine-d₄ (hydrochloride) is the deuterium labeled Promethazine hydrochloride. Promethazine hydrochloride is the first-generation antihistamine; strong antagonist of the H1 receptor and moderate mACh receptor antagonist, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.

HY-W654098

Cefazolin-13C2,15N sodium
Cefazolin- ¹³C₂, ¹⁵N (sodium) is ¹³C and ¹⁵N labeled Cefazolin (sodium). Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).

HY-B1892S1

Cefazolin-13C2,15N
Cefazolin- ¹³C₂, ¹⁵N (Cephazolin- ¹³C₂, ¹⁵N) is ¹³C and ¹⁵N labeled Cefazolin. Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .

HY-14275S

Verapamil-d3
Verapamil-d₃ ((±)-Verapamil-d₃) is deuterium labeled Verapamil. Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-14275S2

Verapamil-d6
Verapamil-d₆ ((±)-Verapamil-d₆) is deuterium labeled Verapamil. Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-14275S1

Verapamil-d7
Verapamil-d₇ is the deuterium labeled Verapamil (HY-14275). Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-A0064S1

Verapamil-d6 hydrochloride

Verapamil-d₆ (CP-16533-1-d₆) hydrochloride is the deuterium labled Verapamil (hydrochloride) (HY-A0064). Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-B0401S

Tolbutamide-d9
Tolbutamide-d₉ is the deuterium labeled Tolbutamide. Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic agent.

HY-B0401S1

Tolbutamide-13C
Tolbutamide- ¹³C is the ¹³C-labeled Tolbutamide. Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic agent.

HY-100641S

4-Hydroxytolbutamide-d9
4-Hydroxytolbutamide-d₉ is the deuterium labeled 4-Hydroxytolbutamide. 4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic .

HY-B0200BS

Cephalexin-d5 monohydrate

Cephalexin-d₅ (monohydrate) is the deuterium labeled Cephalexin monohydrate. Cephalexin monohydrate is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin monohydrate kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-B0200S

Cephalexin-d5
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

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