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Results for "

diarrhea

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Acyltransferase (2) Adenylate Cyclase (1) Adrenergic Receptor (2) AMPK (1) Antibiotic (9) Apoptosis (8) Autophagy (4) Bacterial (11) Biochemical Assay Reagents (1) Calcium Channel (3) CaMK (1) Carboxylesterase (CES) (2) CFTR (2) Chloride Channel (1) Cholinesterase (ChE) (5) CMV (2) COX (2) DNA/RNA Synthesis (5) Endogenous Metabolite (8) Epigenetic Reader Domain (1) FGFR (1) Flavivirus (5) Free Fatty Acid Receptor (1) Fungal (3) GLUT (3) Glycosidase (1) GSK-3 (1) Guanylate Cyclase (3) HCV (1) HDAC (1) Histone Methyltransferase (1) HSV (2) Influenza Virus (2) Interleukin Related (1) Isotope-Labeled Compounds (4) Mitophagy (2) Motilin Receptor (2) mTOR (1) nAChR (1) NF-κB (1) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (2) p38 MAPK (1) Parasite (5) Phosphodiesterase (PDE) (1) PI4K (1) Potassium Channel (5) PPAR (1) Ras (1) Reactive Oxygen Species (ROS) (1) Reference Standards (10) SARS-CoV (2) Tau Protein (1) TGF-β Receptor (1) TNF Receptor (2)
By Research Areas:	Cancer (14) Cardiovascular Disease (5) Infection (27) Inflammation/Immunology (14) Metabolic Disease (17) Neurological Disease (6)
Oligonucleotides:	Release-retarding Agents (1) Nucleotides and their Analogs (1) Nucleosides and their Analogs (1) Thickeners (1) G (1) Emulsifiers (1)

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-154659

Polycarbophil	Biochemical Assay Reagents	Others
Polycarbophil is an orally active hydrophilic polymer. Polycarbophil achieves bioadhesion through hydrogen bonding between carboxyl groups and mucosal surfaces, and prolongs compound retention time and regulates compound release through swelling properties. Polycarbophil relieves constipation and diarrhea .

HY-P5077A

Guanylin (mouse, rat) (TFA)	Guanylate Cyclase	Metabolic Disease
Guanylin (mouse, rat) TFA, a petide, is composed of 15 amino acids. Guanylin (mouse, rat) TFA is an activator of intestinal guanylate cyclase. Guanylin (mouse, rat) TFA can be used for the research of diarrhea .

HY-149276

SLC26A3-IN-2 1 Publications Verification	GLUT	Metabolic Disease
SLC26A3-IN-2 is an orally active inhibitor of anion exchanger protein SLC26A3 (IC₅₀=360 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea .

HY-131976

BVDV-IN-1	Flavivirus	Infection
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of *bovine viral diarrhea* virus (BVDV), with an EC₅₀** of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC) .

HY-155181

CES2-IN-1	Carboxylesterase (CES)	Cancer
CES2-IN-1 (Compound 24) is a reversible and selective CES2 inhibitor (IC₅₀: 6.72 μM for human CES2). CES2-IN-1 reduces the level of CES2 in living cells. CES2-IN-1 is effective against Irinotecan (HY-16562)-induced delayed diarrhea and DSS-induced ulcerative colitis .

HY-155228

LK-44	Others	Inflammation/Immunology
hCES2A-IN-2 (Compound 44) is an orally active human carboxylesterase 2 (hCES2A) inhibitor (IC₅₀: 5.02 μM). hCES2A-IN-2 improves Irinotecan (HY-16562)-induced delayed diarrhea .

HY-B0519C

Tylosin lactate	Bacterial	Infection
Tylosin (lactate) is an anti-bacterial agent that can target spore-forming bacteria. Tylosin (lactate) can increase the levels of Enterococcus and lactobacilli in dogs' feces and help relieve tylosin-responsive diarrhea .

HY-176465

CES2A-IN-3	Carboxylesterase (CES)	Inflammation/Immunology
CES2A-IN-3 (Compound 9d) is a potent serine-targeting covalent human carboxylesterase 2A (hCES2A) inhibitor with an IC₅₀ value of 0.12 nM. CES2A-IN-3 is promising for research of diarrhea and ulcerative colitis .

HY-P5077

Guanylin (mouse, rat)	Guanylate Cyclase	Metabolic Disease
Guanylin (mouse, rat), a petide, is composed of 15 amino acids. Guanylin (mouse, rat) is an activator of intestinal guanylate cyclase. Guanylin (mouse, rat) can be used for the research of diarrhea .

HY-149802

SLC26A3-IN-1	GLUT	Metabolic Disease
SLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC₅₀=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea .

HY-107547

BPIPP	Guanylate Cyclase Adenylate Cyclase	Metabolic Disease
BPIPP is a guanylyl cyclase type C (GC-C) and adenylyl cyclase inhibitor that can suppress cyclic nucleotide synthesis. BPIPP inhibits chloride-ion transport stimulated by activation of guanylyl or adenylyl cyclases, and has the potential for diarrhea research .

HY-A0274

Ramosetron YM060 free base	5-HT Receptor	Others
Ramosetron (YM060 free base) is an orally active 5-HT₃ antagonist that improves dysphoria, interference with activity and food avoidance. Ramosetron is promising for research of irritable bowel syndrome with diarrhea .

HY-401913

endo CNTinh-03	Phosphodiesterase (PDE)	Infection Cancer
Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC₅₀ is 4 μM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model .

HY-N5142

α-Terpineol	Bacterial Antibiotic NF-κB AMPK Fungal	Infection Neurological Disease Metabolic Disease Inflammation/Immunology
α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

HY-105099

Rifalazil KRM-1648; ABI-1648	Antibiotic DNA/RNA Synthesis Bacterial	Infection Inflammation/Immunology
Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase . Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml . Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB) .

HY-107358A

Lidamidine hydrochloride WHR-1142A	Adrenergic Receptor	Others
Lidamidine hydrochloride (WHR-1142A) is an α2-adrenergic receptor agonist and antidiarrheal agent .

HY-105099R

Rifalazil (Standard) KRM-1648 (Standard); ABI-1648 (Standard)	Antibiotic Reference Standards DNA/RNA Synthesis Bacterial	Infection Inflammation/Immunology
Rifalazil (Standard) is the analytical standard of Rifalazil. This product is intended for research and analytical applications. Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase[1]. Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml[3]. Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB)[2].

HY-B0418AS

Loperamide-d6 hydrochloride R-18553-d₆ hydrochloride	Opioid Receptor Autophagy	Neurological Disease Metabolic Disease
Loperamide-d₆ (hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride is an opioid receptor agonist for the treatment of diarrhea .

HY-W009123

Erucamide cis-13-Docosenamide	Endogenous Metabolite	Others
Erucamide inhibits intestinal diarrhea.Erucamide also regulates the volume of body fluids in other organs. Erucamide has the ability to promote angiogenesis .

HY-14603

Clioquinol 5 Publications Verification Iodochlorohydroxyquinoline	Fungal Autophagy Mitophagy Antibiotic Parasite	Infection Cancer
Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic .

HY-122307A

Sulisatin disodium DAN-603 disodium	Bacterial	Metabolic Disease
Sulisatin (DAN-603) disodium is an anionic diarrhea-promoting compound. During oral administration, Sulisatin disodium is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon .

HY-107358

Lidamidine WHR-1142A free base	Adrenergic Receptor	Metabolic Disease
Lidamidine (WHR-1142A free base) is an α2-adrenergic receptor agonist and antidiarrheal agent .

HY-156131

Loperamide ADL 2-1294	Opioid Receptor	Inflammation/Immunology
Loperamide (ADL 2-1294) is a selective μ opioid receptor agonist with K_is of 3, 48 and 1156 nM against μ, δ and κ opioid receptor, respectively. Loperamide can be used as an antidiarrheal agent .

HY-138594

5'-O-TBDMS-N2-ibu-dG	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Infection Cancer
5'-O-TBDMS-N2-ibu-dG is a nucleoside derivative and can be used for lead compounds synthesis with anti-bovine viral diarrhea virus activity .

HY-W009123R

Erucamide (Standard) cis-13-Docosenamide (Standard)	Endogenous Metabolite Reference Standards	Others
Erucamide (Standard) is the analytical standard of Erucamide. This product is intended for research and analytical applications. Erucamide inhibits intestinal diarrhea.Erucamide also regulates the volume of body fluids in other organs. Erucamide has the ability to promote angiogenesis .

HY-14603R

Clioquinol (Standard) Iodochlorohydroxyquinoline (Standard)	Reference Standards Fungal Autophagy Mitophagy Antibiotic Parasite	Infection Cancer
Clioquinol (Standard) is the analytical standard of Clioquinol. This product is intended for research and analytical applications. Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic .

HY-B0595

Ramosetron Hydrochloride YM060	5-HT Receptor	Neurological Disease Inflammation/Immunology Cancer
Ramosetron (YM060 free base) Hydrochloride is an orally active 5-HT₃ antagonist that improves dysphoria, interference with activity and food avoidance. Ramosetron Hydrochloride is promising for research of irritable bowel syndrome with diarrhea .

HY-111613

Pinaverium bromide 4 Publications Verification	Calcium Channel	Cancer
Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients .

HY-126732

L-640876	Antibiotic Bacterial	Infection
L-640876 is a broad-spectrum and orally active lactam antimicrobial agent. L-640876 showa MIC90 of 0.125 pg/mL for the E. coli strains, 2 /mg/mL for the S.choleraerai strains and 4 pg/mL for the S. typhinwrium strains .

HY-114621B

DB772 free base	Flavivirus	Infection
DB772 free base is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 free base also has anti-prion activity .

HY-114621

DB772	Flavivirus	Infection
DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity .

HY-114621A

DB772 hydrate	Flavivirus	Infection
DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity .

HY-135319

Strictinin	Bacterial Antibiotic	Infection
Strictinin is a phenolic compound isolated from Pu'er teas. Strictinin has potential antiviral, antibacterial and laxative activities. Strictinin occurs by accelerating intestinal transit rather than enhancing gastric emptying, increasing food intake, or inducing diarrhea in rats.

HY-103583

KDU731	PI4K Parasite	Infection
KDU731, an orally active C. parvum PI4K inhibitor with an IC₅₀ value of 25 nM, blocks Cryptosporidium infection in vitro and in vivo . KDU731 is a promising agent candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety .

HY-13234

Rifaximin 5 Publications Verification	Bacterial Antibiotic DNA/RNA Synthesis	Infection Cancer
Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .

HY-13234R

Rifaximin (Standard)	Reference Standards Bacterial Antibiotic DNA/RNA Synthesis	Infection Cancer
Rifaximin (Standard) is the analytical standard of Rifaximin. This product is intended for research and analytical applications. Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .

HY-111613S

Pinaverium bromide-d4	Isotope-Labeled Compounds Calcium Channel	Others
Pinaverium bromide-d₄ is deuterium labeled Pinaverium bromide. Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients .

HY-101981

Uridine 5'-monophosphate 1 Publications Verification 5'-Uridylic acid	Endogenous Metabolite Cholinesterase (ChE) Potassium Channel Apoptosis	Cardiovascular Disease Metabolic Disease
Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .

HY-106018A

Mitemcinal fumarate GM 611 fumarate	Motilin Receptor	Others
Mitemcinal fumarate is an oral motilium agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal fumarate may be a constipation suppressant due to its early onset and short duration of action.

HY-N1067

Xanthohumol Maximum Cited Publications 11 Publications Verification	COX Acyltransferase Apoptosis HSV CMV Influenza Virus	Infection Cancer
Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against *bovine viral diarrhea* virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV)**.

HY-N1972

Sennoside C	Others	Neurological Disease Metabolic Disease
Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC₅₀: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases .

HY-111613R

Pinaverium bromide (Standard)	Reference Standards Calcium Channel	Cancer
Pinaverium bromide (Standard) is the analytical standard of Pinaverium bromide. This product is intended for research and analytical applications. Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients .

HY-W013175

Uridine 5'-monophosphate disodium salt 1 Publications Verification 5'-Uridylic acid disodium salt	Endogenous Metabolite Cholinesterase (ChE) Potassium Channel Apoptosis	Cardiovascular Disease Metabolic Disease
Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .

HY-12633

GS-6620	HCV	Inflammation/Immunology
GS-6620 is potent and selective pangenotype HCV inhibitor against HCV replicons of genotypes 1 to 6 (EC₅₀: 0.048 to 0.68 μM). GS-6620 shows limited activities against other viruses, maintaining only some of its activity against the closely related bovine viral diarrhea virus (EC₅₀, 1.5 μM) .

HY-172772

Anti-PEDV agent 1	Flavivirus	Infection
Anti-PEDV agent 1 (Compound D39) is a highly effective anti-Porcine epidemic diarrhea virus (PEDV) agent with an EC₅₀ value of 0.09 μM. Anti-PEDV agent 1 blocks the early internalization of PEDV during viral entry by modulating intracellular Ca ²⁺ homeostasis. Anti-PEDV agent 1 is promising for research of PEDV infections .

HY-106018

Mitemcinal GM 611	Motilin Receptor	Others
Mitemcinal (GM 611) is an oral motilin receptor agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal may be a constipation suppressant due to its early onset and short duration of action .

HY-108772

Crofelemer Provir; SP 303	CFTR Chloride Channel	Others
Crofelemer (Provir) is an orally active antidiarrheal agent. Crofelemer acts on the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC) , which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer can be used in the research of diarrheal diseases .

HY-N1067R

Xanthohumol (Standard)	Reference Standards COX Acyltransferase Apoptosis HSV CMV Influenza Virus	Infection Cancer
Xanthohumol (Standard) is the analytical standard of Xanthohumol. This product is intended for research and analytical applications. Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).

HY-101981R

Uridine 5'-monophosphate (Standard) 5'-Uridylic acid (Standard)	Reference Standards Endogenous Metabolite	Others
Uridine 5'-monophosphate (Standard) is the analytical standard of Uridine 5'-monophosphate. This product is intended for research and analytical applications. Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.

HY-172768

SCUT1-2	Bacterial	Infection
SCUT1-2 is a bifunctional antibacterial agent with good oral bioavailability in mice (F=56.8%). SCUT1-2 can kill the vegetative cells of C. difficile with a MIC of 0.06-0.50 μg/mL, and inhibit spore germination in vitro. SCUT1-2 could alleviate the symptoms of weight loss and diarrhea in mice caused by C. difficile infection (CDI) and prevent recurrent CDI .

Cat. No.	Product Name

HY-L224

Diarrhea-Related Traditional Chinese Medicine Active Compound Library

2,504 compounds

Diarrhea is a disease symptom, and the pathophysiologic basis of diarrhea is a disturbance in intestinal water and electrolyte balance, which may be due to increased secretion of osmotically active electrolytes (secretory diarrhea) or increased intake of osmotically active substances (osmotic diarrhea). Food poisoning, pathogenic bacterial infections, and intestinal-related diseases can all contribute to the development of diarrhea. Traditional Chinese Medicine (TCM) considers diarrhea to be a symptom of an imbalance in the body's systems, particularly related to the functions of the spleen and stomach. Spleen qi deficiency, dampness-heat, liver and spleen disharmony are closely related to diarrhea. Many types of Chinese herbs regulate the function of diarrhea, such as: Dysosmae Verspiellis Rhixoma Et Radix, Ginkgo Semen, Forsythiae Fructus, and Campsis Flos.

MCE can provide 2,504 active monomers that can be obtained from TCM herbs with diarrhea-regulating functions, which can be applied to drug development and disease mechanism research.

Cat. No.	Product Name	Target	Research Area

HY-P5077A

Guanylin (mouse, rat) (TFA)	Guanylate Cyclase	Metabolic Disease
Guanylin (mouse, rat) TFA, a petide, is composed of 15 amino acids. Guanylin (mouse, rat) TFA is an activator of intestinal guanylate cyclase. Guanylin (mouse, rat) TFA can be used for the research of diarrhea .

HY-P5077

Guanylin (mouse, rat)	Guanylate Cyclase	Metabolic Disease
Guanylin (mouse, rat), a petide, is composed of 15 amino acids. Guanylin (mouse, rat) is an activator of intestinal guanylate cyclase. Guanylin (mouse, rat) can be used for the research of diarrhea .

HY-106128

Lagatide BN 52080	Peptides	Infection
Lagatide (BN 52080), a heptapeptide, is a short C-terminal analog of sorbin. Lagatide has proabsorptive and antisecretory effect in the different parts of the intestine. Lagatide can be used for the research of chronic diarrhea .

Cat. No.	Product Name	Chemical Structure

HY-B0418AS

Loperamide-d6 hydrochloride
Loperamide-d₆ (hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride is an opioid receptor agonist for the treatment of diarrhea .

HY-101981S

Uridine 5'-monophosphate-15N2

Uridine 5'-monophosphate- ¹⁵N₂ (5'-Uridylic acid- ¹⁵N₂) is the ¹⁵N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .

HY-W013175S2

Uridine 5'-monophosphate-13C9,15N2 disodium

Uridine 5'-monophosphate- ¹³C₉, ¹⁵N₂ disodium is the ¹³C and ¹⁵N labeled Uridine 5'-monophosphate disodium salt (HY-W013175). Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .

HY-111613S

Pinaverium bromide-d4
Pinaverium bromide-d₄ is deuterium labeled Pinaverium bromide. Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients .

HY-N5142S1

α-Terpineol-d6

α-Terpineol-d₆ is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

Cat. No.	Product Name		Classification