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diabetic diseases

" in MedChemExpress (MCE) Product Catalog:

89

Inhibitors & Agonists

1

Screening Libraries

1

Fluorescent Dye

8

Peptides

4

Inhibitory Antibodies

33

Natural
Products

6

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-164368
    GLUT4 activator 2

    		Phosphodiesterase (PDE) Insulin Receptor Metabolic Disease
    GLUT4 activator 2 (C59) is an insulin sensitizer, which can be used for research of diabetic diseases. GLUT4 activator 2 improves glucose uptake and insulin sensitivity in rodents. GLUT4 activator 2 interacts with Unc119 and Unc119B resulting in increased insulin sensitivity and GLUT4 translocation .
    GLUT4 activator 2
  • HY-128442
    Phenyl sulfate

    Phenyl hydrogen sulfate

    		 Endogenous Metabolite Metabolic Disease
    Phenyl sulfate is an orally active gut microbiota-derived metabolite. Phenyl sulfate induces albuminuria and podocyte damage in experimental models of diabetes. Phenyl sulfate can be used as a disease marker and future therapeutic target in diabetic kidney disease .
    Phenyl sulfate
  • HY-113089A
    Epsilon-(gamma-glutamyl)-lysine TFA

    H-Glu(H-Lys-OH)-OH TFA; γ-Glu-ε-Lys TFA

    		 Endogenous Metabolite Metabolic Disease
    Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
    Epsilon-(gamma-glutamyl)-lysine TFA
  • HY-N2181
    Acetylshikonin
    1 Publications Verification

    		 Cytochrome P450 Apoptosis Bacterial Autophagy Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Acetylshikonin is an oral active anti-cancer, anti-inflammatory, antioxidant, anti-fertility, antibacterial, and neuroprotective agent. Acetylshikonin is a inhibitor of acetylcholinase (AChE) (IC50=34.6 μM) and nonselective cytochrome P450. Acetylshikonin can induce Apoptosis and Autophagy in cancer cells. Acetylshikonin regulates blood glucose, liver fat metabolism, and renal fibrosis, and is used in the study of diabetes, diabetic nephropathy (DN), obesity, and nonalcoholic fatty liver disease (NAFLD) .
    Acetylshikonin
  • HY-N7960
    (2S)-Pteroside A

    		Others Metabolic Disease
    (2S)-Pteroside A is a pteroside from the rhizomes of subsp. aquilinum of bracken fern, which is promising for research of diabetic diseases .
    (2S)-Pteroside A
  • HY-N13194
    (2R)-Pteroside B

    		Others Metabolic Disease
    (2R)-Pteroside B is a pterosin-associated glycoside from the rhizomes of subsp. aquilinum of bracken fern, which is promising for research of diabetic diseases .
    (2R)-Pteroside B
  • HY-153092
    Avenciguat

    BI-685509

    		 Guanylate Cyclase Cardiovascular Disease Metabolic Disease
    Avenciguat (BI-685509) is a potent and orally active sGC activator. Avenciguat restores cyclic guanosine monophosphate (cGMP) and improves functionality of nitric oxide (NO) pathways. Avenciguat can be used in research of chronic kidney disease (CKD) and diabetic kidney disease (DKD) .
    Avenciguat
  • HY-128442R
    Phenyl sulfate (Standard)

    		Endogenous Metabolite Metabolic Disease
    Phenyl sulfate (Standard) is the analytical standard of Phenyl sulfate. This product is intended for research and analytical applications. Phenyl sulfate is an orally active gut microbiota-derived metabolite. Phenyl sulfate induces albuminuria and podocyte damage in experimental models of diabetes. Phenyl sulfate can be used as a disease marker and future therapeutic target in diabetic kidney disease .
    Phenyl sulfate (Standard)
  • HY-161026
    JM-9

    		Toll-like Receptor (TLR) Inflammation/Immunology
    JM-9 is a inhibitor of MD2. JM-9 suppresses high glucose and palmitic acid -induced inflammation in MPMs. JM-9 improves diabetic kidney disease by inhibiting MD2-mediated inflammation .
    JM-9
  • HY-113089
    Epsilon-(gamma-glutamyl)-lysine

    H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys

    		 Endogenous Metabolite Metabolic Disease
    Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
    Epsilon-(gamma-glutamyl)-lysine
  • HY-113089AR
    Epsilon-(gamma-glutamyl)-lysine TFA (Standard)

    		Endogenous Metabolite Metabolic Disease
    Epsilon-(gamma-glutamyl)-lysine (TFA) (Standard) is the analytical standard of Epsilon-(gamma-glutamyl)-lysine (TFA). This product is intended for research and analytical applications. Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
    Epsilon-(gamma-glutamyl)-lysine TFA (Standard)
  • HY-B0202A
    Irbesartan hydrochloride

    SR-47436 hydrochloride; BMS-186295 hydrochloride

    		 Angiotensin Receptor Apoptosis Cardiovascular Disease Neurological Disease Metabolic Disease
    Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .
    Irbesartan hydrochloride
  • HY-B0202
    Irbesartan
    5 Publications Verification

    SR-47436; BMS-186295

    		 Angiotensin Receptor Apoptosis Cardiovascular Disease Endocrinology
    Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .
    Irbesartan
  • HY-B0202S3
    Irbesartan-d7

    SR-47436-d7; BMS-186295-d7

    		 Apoptosis Angiotensin Receptor Isotope-Labeled Compounds Cardiovascular Disease Endocrinology
    Irbesartan-d7 is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .
    Irbesartan-d7
  • HY-B0202AS
    Irbesartan-d7 hydrochloride

    SR-47436-d7 hydrochloride; BMS-186295-d7 hydrochloride

    		 Apoptosis Angiotensin Receptor Isotope-Labeled Compounds Neurological Disease Metabolic Disease
    Irbesartan-d7 hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .
    Irbesartan-d7 hydrochloride
  • HY-N1362
    Salvianolic acid B
    10+ Cited Publications

    Lithospermic acid B

    		 Autophagy Cardiovascular Disease
    Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication.
    Salvianolic acid B
  • HY-150069
    UBX1325

    		Bcl-2 Family Apoptosis Metabolic Disease
    UBX1325 is an Bcl-xL inhibitor that promotes apoptosis in senescent cells. UBX1325 is a potent anti-aging agent that can be used in studies of age-related eye diseases such as diabetic macular oedema (DME), age-related macular degeneration (AMD) and diabetic retinopathy (DR) .
    UBX1325
  • HY-U00059
    Pyrrole-derivative1

    		Drug Derivative Metabolic Disease
    Pyrrole-derivative1 is extracted from patent WO/2002/085851A1, example 2, developed for the treatment of diabetic disease.
    Pyrrole-derivative1
  • HY-N11286
    Tridocosahexaenoylglycerol

    TG-DHA; Meganol D

    		 Others Neurological Disease Metabolic Disease Inflammation/Immunology
    Tridocosahexaenoylglycerol (TG-DHA) is an orally active dietary supplement that improves autoimmune encephalomyelitis in mice. Tridocosahexaenoylglycerol shows beneficial effects on neurodegenerative diseases and also improves macular function in diabetic retinopathy. Tridocosahexaenoylglycerol can be used for research on neurological diseases, inflammatory immune diseases, and metabolic diseases .
    Tridocosahexaenoylglycerol
  • HY-N0502
    Mogroside V
    1 Publications Verification

    		 Reactive Oxygen Species (ROS) Metabolic Disease Cancer
    Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
    Mogroside V
  • HY-N2608
    7-O-Ethylmorroniside

    		Others Metabolic Disease
    7-O-Ethylmorroniside is a iridoid glucoside from the fruit of Cornus officinalis which is a traditional medicine in China and used for the reserch of kidney diseases, including diabetic nephropathy .
    7-O-Ethylmorroniside
  • HY-111603S
    Dobesilate-d6 calcium

    		Isotope-Labeled Compounds Apoptosis Others
    Dobesilate-d6 (calcium) is deuterium labeled Calcium dobesilate. Calcium dobesilate, a vasoprotective, is widely used in chronic venous disease, diabetic retinopathy and the symptoms of haemorrhoidal attack in many countries.
    Dobesilate-d6 calcium
  • HY-N11286R
    Tridocosahexaenoylglycerol (Standard)

    TG-DHA (Standard); Meganol D (Standard)

    		 Reference Standards Others Neurological Disease Metabolic Disease Inflammation/Immunology
    Tridocosahexaenoylglycerol (Standard) is the analytical standard of Tridocosahexaenoylglycerol. This product is intended for research and analytical applications. Tridocosahexaenoylglycerol (TG-DHA) is an orally active dietary supplement that improves autoimmune encephalomyelitis in mice. Tridocosahexaenoylglycerol shows beneficial effects on neurodegenerative diseases and also improves macular function in diabetic retinopathy. Tridocosahexaenoylglycerol can be used for research on neurological diseases, inflammatory immune diseases, and metabolic diseases .
    Tridocosahexaenoylglycerol (Standard)
  • HY-111603
    Calcium dobesilate
    1 Publications Verification

    		 Apoptosis Metabolic Disease Inflammation/Immunology
    Calcium dobesilate is a vascular protector with oral activity that can clear hydroxyl free radicals, with an IC50 of 1.1 pM. Calcium dobesilate has antioxidant activity and helps to reduce oxidative stress and inflammation in the retinas of diabetic mice. Calcium dobesilate can be used to study chronic venous diseases, diabetic retinopathy, and the occurrence of hemorrhoids, among other conditions .
    Calcium dobesilate
  • HY-N15532
    Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside

    		Trk Receptor Neurological Disease
    Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside (Compound 12) is a nerve growth factor (NGF) secretion promoter, which is found in plants of the genus Piper. Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside is promising for research of neurodegenerative diseases (such as Parkinson's disease and Alzheimer's disease) and diabetic polyneuropathy .
    Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside
  • HY-N1362R
    Salvianolic acid B (Standard)

    Lithospermic acid B (Standard)

    		 Reference Standards Autophagy Cardiovascular Disease
    Salvianolic acid B (Standard) is the analytical standard of Salvianolic acid B. This product is intended for research and analytical applications. Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication.
    Salvianolic acid B (Standard)
  • HY-111603R
    Calcium dobesilate (Standard)

    		Reference Standards Apoptosis Others
    Calcium dobesilate (Standard) is the analytical standard of Calcium dobesilate. This product is intended for research and analytical applications. Calcium dobesilate, a vasoprotective, is widely used in chronic venous disease, diabetic retinopathy and the symptoms of haemorrhoidal attack in many countries.
    Calcium dobesilate (Standard)
  • HY-137322
    THX-B

    		Neurotensin Receptor Neurological Disease Metabolic Disease
    THX-B is a potent and non-peptidic p75 NTR (neurotrophin receptor p75) antagonist. THX-B can be used in the research of diabetic kidney disease, neurodegenerative and inflammatory disorders .
    THX-B
  • HY-160186
    20-SOLA

    		Cytochrome P450 Cardiovascular Disease Metabolic Disease Endocrinology
    20-SOLA is an orally active 20-HETE antagonist. 20-SOLA greatly ameliorates changes in blood pressure and renal injury associated with a Streptozotocin (STZ) (HY-13753)-diabetic mouse model. 20-SOLA facilitates the restoration of coronary collateral growth (CCG) after ischemic injury. 20-SOLA can be studied for research in cardiovascular diseases and diabetes .
    20-SOLA
  • HY-P991289
    EBI-031

    		Interleukin Related Inflammation/Immunology
    EBI-031 is a humanized antibody inhibitor targeting IL-6. EBI-031 is a nonsteroidal anti-inflammatory inhibitor. EBI-031 has superior biological efficacy in the management of ocular diseases, such as non-infectious uveitis (NIU) and retinal vascular diseases, and other disease including non-uveitic macular edema and diabetic macular edema .
    EBI-031
  • HY-N0502R
    Mogroside V (Standard)

    		Reactive Oxygen Species (ROS) Reference Standards Metabolic Disease Cancer
    Mogroside V (Standard) is the analytical standard of Mogroside V. This product is intended for research and analytical applications. Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
    Mogroside V (Standard)
  • HY-B1392A
    Esmolol

    		Adrenergic Receptor Caspase Apoptosis Aldose Reductase Neurokinin Receptor Cardiovascular Disease Endocrinology Cancer
    Esmolol is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol exerts its antiarrhythmic effect by activating Neurokinin 1 Receptor. Esmolol attenuates post resuscitation myocardial dysfunction. Esmolol improves diabetic wound healing by inhibiting aldose reductase and the production of advanced glycation end products and promoting fibroblast migration. Esmolol can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers .
    Esmolol
  • HY-B1392
    Esmolol hydrochloride
    3 Publications Verification

    		 Adrenergic Receptor Caspase Apoptosis Aldose Reductase Neurokinin Receptor Cardiovascular Disease Endocrinology Cancer
    Esmolol hydrochloride is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol hydrochloride exerts its antiarrhythmic effect by activating Neurokinin 1 Receptor. Esmolol hydrochloride attenuates post resuscitation myocardial dysfunction. Esmolol hydrochloride improves diabetic wound healing by inhibiting aldose reductase and the production of advanced glycation end products and promoting fibroblast migration. Esmolol hydrochloride can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers .
    Esmolol hydrochloride
  • HY-105185
    Fidarestat
    3 Publications Verification

    SNK 860

    		 Aldose Reductase Metabolic Disease
    Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.
    Fidarestat
  • HY-P9970
    Infliximab
    10+ Cited Publications

    Avakine; CT-P13

    		 TNF Receptor Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2). Infliximab has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research .
    Infliximab
  • HY-17374
    Benfotiamine
    1 Publications Verification

    S-Benzoylthiamine O-monophosphate

    		 SARS-CoV HIV Infection Metabolic Disease Inflammation/Immunology
    Benfotiamine (S-Benzoylthiamine O-monophosphate) is a vitamin B1 derivative that exhihibits potent antioxidative and anti-inflammatory activity. Benfotiamine can be used for the research of various secondary diabetic complications. Benfotiamine also can be used in infectious diseases such as HIV and COVID-19 .
    Benfotiamine
  • HY-159944
    PPARγ agonist 14

    		PPAR Neurological Disease Metabolic Disease Inflammation/Immunology
    PPARγ agonist 14 (compound 3) is a PPARy agonist (EC50=2.4 μM) with anti-diabetic activity. PPARγ agonist 14 can improve intracellular glucose uptake, promote insulin release, and lower blood sugar. In addition, PPARγ agonist 14 also improves mitochondrial function, reduces oxidative stress, and inhibits inflammatory factors. PPARγ agonist 14 can be used in the study of neurodegenerative diseases, neuroinflammatory diseases, and other diseases .
    PPARγ agonist 14
  • HY-141885
    APOL1-IN-1

    		Apolipoprotein Metabolic Disease
    APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD) .
    APOL1-IN-1
  • HY-134769
    OPC-163493

    		Mitochondrial Metabolism Reactive Oxygen Species (ROS) Cardiovascular Disease Metabolic Disease
    OPC-163493 is an orally active and liver-targeted mitochondrial uncoupling agent. OPC-163493 reduces the production of mitochondrial Δψ and ROS. OPC-163493 has anti-diabetic and lipid-lowering effects. In addition, OPC-163493 has a protective effect on cardiovascular disease .
    OPC-163493
  • HY-B1392S
    Esmolol-d7 hydrochloride

    		Isotope-Labeled Compounds Adrenergic Receptor Autophagy Mitophagy Cardiovascular Disease Endocrinology Cancer
    Esmolol-d7 hydrochloride is the deuterium labeled Esmolol hydrochloride (HY-B1392). Esmolol hydrochloride is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol hydrochloride exerts its antiarrhythmic effect by activating Neurokinin 1 Receptordiabetic wound healing by inhibiting (aldose reductase) and the production of advanced glycation end products and promoting fibroblast migration. Esmolol hydrochloride can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers .
    Esmolol-d7 hydrochloride
  • HY-B1392R
    Esmolol hydrochloride (Standard)

    		Reference Standards Adrenergic Receptor Autophagy Mitophagy Cardiovascular Disease Endocrinology Cancer
    Esmolol hydrochloride (Standard) is the analytical standard of Esmolol hydrochloride (HY-B1392).This product is intended for research and analytical applications. Esmolol hydrochloride is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol hydrochloride exerts its antiarrhythmic effect by activating Neurokinin 1 Receptordiabetic wound healing by inhibiting aldose reductase and the production of advanced glycation end products and promoting fibroblast migration. Esmolol hydrochloride can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers .
    Esmolol hydrochloride (Standard)
  • HY-75625
    2-Hydroxy-4-methoxybenzoic acid

    4-Methoxysalicylic Acid

    		 Biochemical Assay Reagents Metabolic Disease Inflammation/Immunology
    2-Hydroxy-4-methoxybenzoic acid (4-Methoxysalicylic Acid) is a phenolic compound isolated from Hemidesmus indicus and other plants. 2-Hydroxy-4-methoxybenzoic acid exhibits anti-diabetic, hypolipidemic, hepatoprotective, and anti-snake venom activities. 2-Hydroxy-4-methoxybenzoic acid can be used in the study of diabetes and its complications, liver diseases, immune-related diseases, and snake venom poisoning .
    2-Hydroxy-4-methoxybenzoic acid
  • HY-D2379
    HMRG

    		Fluorescent Dye Endocrinology Cancer
    HMRG is a type of hydroxymethyl rhodamine green fluorescent scaffold, featuring an open non-cyclic structure. HMRG can produce significant dynamic fluorescence changes through a one-step enzymatic reaction at physiological pH, which is useful for developing various probes. Fluorescent probes based on HMRG can be used for fluorescence detection of diseases such as tumors and diabetic nephropathy .
    HMRG
  • HY-N0680
    Thiamine hydrochloride

    Thiamine chloride hydrochloride; Vitamin B1 hydrochloride

    		 Endogenous Metabolite Keap1-Nrf2 Toll-like Receptor (TLR) NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.Thiamine hydrochloride activates NrF-2/HO-1 and inhibits TLR4, NF-κB. Thiamine hydrochloride has neuroprotective and anti-inflammatory effects. Thiamine hydrochloride can be used in the studys of diabetic complications, neurological diseases, cancers, and colitis .
    Thiamine hydrochloride
  • HY-17374R
    Benfotiamine (Standard)

    S-Benzoylthiamine O-monophosphate (Standard)

    		 Reference Standards HIV SARS-CoV Infection Metabolic Disease Inflammation/Immunology
    Benfotiamine (Standard) is the analytical standard of Benfotiamine. This product is intended for research and analytical applications. Benfotiamine (S-Benzoylthiamine O-monophosphate) is a vitamin B1 derivative that exhihibits potent antioxidative and anti-inflammatory activity. Benfotiamine can be used for the research of various secondary diabetic complications. Benfotiamine also can be used in infectious diseases such as HIV and COVID-19 .
    Benfotiamine (Standard)
  • HY-P9970A
    Infliximab (Anti-TNF-α)

    Avakine (Anti-TNF-α); CT-P13 (Anti-TNF-α)

    		 TNF Receptor Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Infliximab (Anti-TNF-α) (Avakine (Anti-TNF-α)) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab (Anti-TNF-α) prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2). Infliximab (Anti-TNF-α) has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research .
    Infliximab (Anti-TNF-α)
  • HY-N0188
    Esculin
    4 Publications Verification

    		 p38 MAPK Inflammation/Immunology Cancer
    Esculin is a fluorescent coumarin glucoside, the active ingredient in ash bark. Esculin has antidiabetic effects, improves cognitive impairment in experimental diabetic nephropathy (DN) via the MAPK signaling pathway, and exerts antioxidant stress and anti-inflammatory effects. Esculin also has anticancer, antibacterial, antiviral, neuroprotective, antithrombotic, and therapeutic properties for eye diseases .
    Esculin
  • HY-P3247
    [D-Ala2]-GIP (human)

    		Insulin Receptor Neurological Disease Metabolic Disease
    [D-Ala2]-GIP (human) is a GIP receptor agonist. [D-Ala2]-GIP (human) improves glucose tolerance. [D-Ala2]-GIP (human) shows neuroprotective activity in MPTP-induced Parkinson's disease model. [D-Ala2]-GIP (human) also improves cognitive function and hippocampal synaptic plasticity in obese diabetic rats. [D-Ala2]-GIP (human) can be used for research of type 2 diabetes, Parkinson's disease, etc
    [D-Ala2]-GIP (human)
  • HY-B0202R
    Irbesartan (Standard)

    SR-47436 (Standard); BMS-186295 (Standard)

    		 Reference Standards Angiotensin Receptor Apoptosis Cardiovascular Disease Endocrinology
    Irbesartan (Standard) is the analytical standard of Irbesartan. This product is intended for research and analytical applications. Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .
    Irbesartan (Standard)
  • HY-176236
    Lipophagy inducer 1

    		LXR Autophagy Metabolic Disease
    Lipophagy inducer 1 (Compound 2726.007) is a lipophagy inducer. Lipophagy inducer 1 has the primary activity of reducing lipid droplet accumulation and rescuing podocyte cell death. Lipophagy inducer 1 exerts its effects by activating lipophagy and regulating the LXR signaling pathway. Lipophagy inducer 1 can be used in the study of the treatment of diabetic nephropathy (DKD) and other diseases related to lipid metabolism disorders .
    Lipophagy inducer 1

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